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MCL coexpression mm9:1113

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:31898496..31898519,+p3@Foxc1
Mm9::chr13:31898529..31898542,+p5@Foxc1
Mm9::chr13:31898637..31898653,+p2@Foxc1
Mm9::chr13:31898729..31898761,+p1@Foxc1
Mm9::chr13:31900702..31900717,+p@chr13:31900702..31900717
+
Mm9::chr13:31911932..31911937,+p@chr13:31911932..31911937
+
Mm9::chr1:95132413..95132419,+p1@Sned1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032808lacrimal gland development0.0132190355174424
GO:0008301DNA bending activity0.0132190355174424
GO:0048844artery morphogenesis0.0132190355174424
GO:0055010ventricular cardiac muscle morphogenesis0.0132190355174424
GO:0001945lymph vessel development0.0132190355174424
GO:0048341paraxial mesoderm formation0.0132190355174424
GO:0055008cardiac muscle morphogensis0.0132190355174424
GO:0008354germ cell migration0.0132190355174424
GO:0046620regulation of organ growth0.0132190355174424
GO:0048644muscle morphogenesis0.0132190355174424
GO:0014855striated muscle cell proliferation0.0132190355174424
GO:0060038cardiac muscle cell proliferation0.0132190355174424
GO:0048340paraxial mesoderm morphogenesis0.0137270838347131
GO:0035265organ growth0.014160535876671
GO:0033002muscle cell proliferation0.014160535876671
GO:0048339paraxial mesoderm development0.014160535876671
GO:0035050embryonic heart tube development0.014160535876671
GO:0035272exocrine system development0.014160535876671
GO:0048010vascular endothelial growth factor receptor signaling pathway0.014160535876671
GO:0030199collagen fibril organization0.014160535876671
GO:0001974blood vessel remodeling0.014160535876671
GO:0001541ovarian follicle development0.0150651585630029
GO:0006022aminoglycan metabolic process0.0150651585630029
GO:0030203glycosaminoglycan metabolic process0.0150651585630029
GO:0003705RNA polymerase II transcription factor activity, enhancer binding0.0150651585630029
GO:0001707mesoderm formation0.0178320069727805
GO:0048332mesoderm morphogenesis0.0178320069727805
GO:0001704formation of primary germ layer0.0178320069727805
GO:0022601menstrual cycle phase0.0178320069727805
GO:0022602menstrual cycle process0.0178320069727805
GO:0014032neural crest cell development0.0178320069727805
GO:0014033neural crest cell differentiation0.0178320069727805
GO:0001657ureteric bud development0.0178320069727805
GO:0003007heart morphogenesis0.0178320069727805
GO:0003018vascular process in circulatory system0.0178320069727805
GO:0035150regulation of tube size0.0178320069727805
GO:0050880regulation of blood vessel size0.0178320069727805
GO:0008585female gonad development0.0178320069727805
GO:0046545development of primary female sexual characteristics0.0178320069727805
GO:0046660female sex differentiation0.0178320069727805
GO:0048762mesenchymal cell differentiation0.0183965889740283
GO:0014031mesenchymal cell development0.0183965889740283
GO:0042698menstrual cycle0.018428993404754
GO:0001656metanephros development0.020258643524998
GO:0007498mesoderm development0.021490739919511
GO:0007219Notch signaling pathway0.021490739919511
GO:0008406gonad development0.021490739919511
GO:0048608reproductive structure development0.0218670327202715
GO:0030198extracellular matrix organization and biogenesis0.0229696108243786
GO:0045137development of primary sexual characteristics0.0229696108243786
GO:0007369gastrulation0.0239868528313534
GO:0007160cell-matrix adhesion0.0239868528313534
GO:0031589cell-substrate adhesion0.0246583985634568
GO:0048609reproductive process in a multicellular organism0.0246583985634568
GO:0032504multicellular organism reproduction0.0246583985634568
GO:0001822kidney development0.0246583985634568
GO:0007548sex differentiation0.0246583985634568
GO:0048732gland development0.0246583985634568
GO:0048729tissue morphogenesis0.0246583985634568
GO:0043010camera-type eye development0.0246583985634568
GO:0003702RNA polymerase II transcription factor activity0.0246583985634568
GO:0006916anti-apoptosis0.0248160060337054
GO:0001655urogenital system development0.0248160060337054
GO:0003006reproductive developmental process0.0265876745998625
GO:0001503ossification0.0276356212817596
GO:0031214biomineral formation0.0276356212817596
GO:0008015blood circulation0.0276356212817596
GO:0003013circulatory system process0.0276356212817596
GO:0043062extracellular structure organization and biogenesis0.0283787282681677
GO:0046849bone remodeling0.0289682437536967
GO:0001654eye development0.0289682437536967
GO:0001701in utero embryonic development0.0326725206490609
GO:0048771tissue remodeling0.0327647466503692
GO:0035239tube morphogenesis0.0387242158163404
GO:0040008regulation of growth0.0387242158163404
GO:0043066negative regulation of apoptosis0.0387242158163404
GO:0043069negative regulation of programmed cell death0.0387322107229055
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0412606140285013
GO:0007517muscle development0.0414846881416702
GO:0007507heart development0.0419486472036053
GO:0048514blood vessel morphogenesis0.0421584126785717
GO:0001501skeletal development0.0431779244119272
GO:0007420brain development0.0431779244119272
GO:0007423sensory organ development0.0431779244119272
GO:0048646anatomical structure formation0.0431779244119272
GO:0045944positive regulation of transcription from RNA polymerase II promoter0.0451391350298262
GO:0035295tube development0.0451391350298262
GO:0001568blood vessel development0.0451391350298262
GO:0022414reproductive process0.0451391350298262
GO:0001944vasculature development0.0451391350298262
GO:0043009chordate embryonic development0.0478740204096205
GO:0009792embryonic development ending in birth or egg hatching0.0479924919607441
GO:0007417central nervous system development0.0489506362419057
GO:0045893positive regulation of transcription, DNA-dependent0.0494713306399622



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
compound organ2.71e-1143
structure with developmental contribution from neural crest6.98e-1192
surface structure2.77e-0722
ecto-epithelium3.06e-0773
cardiovascular system5.96e-0723
circulatory system5.96e-0723


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.08574
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.694761
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.11.04397
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.648475
MA0056.10
MA0057.10.117936
MA0058.10.384683
MA0059.10.397033
MA0060.11.90283
MA0061.11.33382
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.121435
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.490396
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.598004
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.12.88877
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.10.311187
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.11.74348
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.13.7618
MA0145.11.05551
MA0146.10.0256827
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.20.573016
MA0039.21.06357
MA0138.20.727395
MA0002.20.592533
MA0137.21.70505
MA0104.20.218974
MA0047.20.626803
MA0112.21.05549
MA0065.20.305574
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.126143
MA0155.10.102995
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.10.878466
MA0163.10.0280055
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.323753
MA0102.21.65195
MA0258.10.246285
MA0259.10.26402
MA0442.10
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