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MCL coexpression mm9:76

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:52410401..52410408,+p6@Slc35f1
Mm9::chr10:83903430..83903450,-p3@Nuak1
Mm9::chr11:110340662..110340679,+p4@Map2k6
Mm9::chr11:110340687..110340700,+p5@Map2k6
Mm9::chr11:113480632..113480660,+p1@Sstr2
Mm9::chr11:69843632..69843643,+p28@Dlg4
Mm9::chr11:70040791..70040799,-p@chr11:70040791..70040799
-
Mm9::chr11:98182595..98182598,-p@chr11:98182595..98182598
-
Mm9::chr11:98187374..98187396,-p@chr11:98187374..98187396
-
Mm9::chr11:98187500..98187512,-p@chr11:98187500..98187512
-
Mm9::chr11:98187516..98187525,-p@chr11:98187516..98187525
-
Mm9::chr11:98187616..98187626,+p@chr11:98187616..98187626
+
Mm9::chr11:98187765..98187774,-p@chr11:98187765..98187774
-
Mm9::chr11:98188005..98188016,-p@chr11:98188005..98188016
-
Mm9::chr11:98189657..98189671,-p@chr11:98189657..98189671
-
Mm9::chr11:98190918..98190951,-p1@Neurod2
Mm9::chr11:98233288..98233299,+p@chr11:98233288..98233299
+
Mm9::chr12:28025601..28025611,-p@chr12:28025601..28025611
-
Mm9::chr12:50478644..50478659,+p@chr12:50478644..50478659
+
Mm9::chr12:50478755..50478772,+p@chr12:50478755..50478772
+
Mm9::chr12:50478808..50478838,+p@chr12:50478808..50478838
+
Mm9::chr12:50482811..50482817,-p@chr12:50482811..50482817
-
Mm9::chr12:50482961..50482982,+p@chr12:50482961..50482982
+
Mm9::chr12:50483044..50483065,+p@chr12:50483044..50483065
+
Mm9::chr12:50483639..50483654,+p1@Foxg1
Mm9::chr12:50483663..50483678,+p3@Foxg1
Mm9::chr12:50484904..50484950,+p@chr12:50484904..50484950
+
Mm9::chr12:50485112..50485144,+p@chr12:50485112..50485144
+
Mm9::chr12:50485245..50485269,+p@chr12:50485245..50485269
+
Mm9::chr12:50485274..50485303,+p@chr12:50485274..50485303
+
Mm9::chr12:50485343..50485352,+p@chr12:50485343..50485352
+
Mm9::chr12:50485353..50485385,+p@chr12:50485353..50485385
+
Mm9::chr12:50485497..50485510,+p@chr12:50485497..50485510
+
Mm9::chr12:50485547..50485567,+p@chr12:50485547..50485567
+
Mm9::chr12:50485922..50485933,+p11@Foxg1
Mm9::chr12:50485948..50485959,+p7@Foxg1
Mm9::chr12:50485973..50486015,+p2@Foxg1
Mm9::chr12:50486431..50486450,+p@chr12:50486431..50486450
+
Mm9::chr12:50486639..50486645,+p@chr12:50486639..50486645
+
Mm9::chr12:51050188..51050205,+p@chr12:51050188..51050205
+
Mm9::chr12:71214719..71214755,-p@chr12:71214719..71214755
-
Mm9::chr13:29045252..29045271,-p5@Sox4
Mm9::chr13:29045274..29045293,-p6@Sox4
Mm9::chr13:29045296..29045307,-p8@Sox4
Mm9::chr13:29045308..29045318,-p10@Sox4
Mm9::chr13:29045321..29045337,-p2@Sox4
Mm9::chr13:77186886..77186936,-p3@Ankrd32
Mm9::chr13:83854934..83854950,+p@chr13:83854934..83854950
+
Mm9::chr13:83878479..83878492,+p1@ENSMUST00000052354
Mm9::chr14:13175827..13175832,-p@chr14:13175827..13175832
-
Mm9::chr14:13176244..13176263,-p@chr14:13176244..13176263
-
Mm9::chr14:13178147..13178185,-p1@Fezf2
Mm9::chr14:13178294..13178303,-p7@Fezf2
Mm9::chr14:13178323..13178347,-p3@Fezf2
Mm9::chr14:13178361..13178386,-p2@Fezf2
Mm9::chr14:22319505..22319521,-p@chr14:22319505..22319521
-
Mm9::chr15:103344762..103344783,+p@chr15:103344762..103344783
+
Mm9::chr15:30103246..30103251,-p@chr15:30103246..30103251
-
Mm9::chr15:43615527..43615530,-p@chr15:43615527..43615530
-
Mm9::chr15:44578120..44578143,-p@chr15:44578120..44578143
-
Mm9::chr15:66663187..66663230,-p9@Sla
Mm9::chr15:83602482..83602487,+p@chr15:83602482..83602487
+
Mm9::chr15:83610405..83610418,+p3@Mpped1
Mm9::chr15:83610429..83610463,+p2@Mpped1
Mm9::chr15:83610464..83610516,+p1@Mpped1
Mm9::chr15:83614756..83614778,+p7@Mpped1
Mm9::chr15:85408549..85408562,-p8@Wnt7b
Mm9::chr15:85408566..85408584,-p6@Wnt7b
Mm9::chr18:65048385..65048406,-p@chr18:65048385..65048406
-
Mm9::chr18:65048430..65048437,-p@chr18:65048430..65048437
-
Mm9::chr18:67020112..67020139,-p1@Mc4r
Mm9::chr18:67020151..67020162,-p2@Mc4r
Mm9::chr18:69753108..69753139,+p8@Tcf4
Mm9::chr18:69753145..69753159,+p14@Tcf4
Mm9::chr18:69753168..69753186,+p12@Tcf4
Mm9::chr18:69753200..69753211,+p@chr18:69753200..69753211
+
Mm9::chr18:69753237..69753261,+p@chr18:69753237..69753261
+
Mm9::chr18:69753278..69753292,+p@chr18:69753278..69753292
+
Mm9::chr1:173959095..173959106,-p@chr1:173959095..173959106
-
Mm9::chr1:178927083..178927100,+p@chr1:178927083..178927100
+
Mm9::chr1:179372543..179372557,+p9@Zfp238
Mm9::chr1:179372625..179372654,+p4@Zfp238
Mm9::chr1:179372666..179372678,+p11@Zfp238
Mm9::chr1:179374820..179374831,+p3@Zfp238
Mm9::chr1:179374862..179374873,+p6@Zfp238
Mm9::chr1:179375791..179375803,+p10@Zfp238
Mm9::chr1:179377246..179377266,+p@chr1:179377246..179377266
+
Mm9::chr1:179377320..179377331,+p@chr1:179377320..179377331
+
Mm9::chr1:179377595..179377604,+p@chr1:179377595..179377604
+
Mm9::chr1:41800521..41800543,+p@chr1:41800521..41800543
+
Mm9::chr1:41800574..41800586,+p@chr1:41800574..41800586
+
Mm9::chr1:42708169..42708173,-p@chr1:42708169..42708173
-
Mm9::chr1:42752654..42752665,+p5@Pou3f3
Mm9::chr1:56853013..56853024,-p@chr1:56853013..56853024
-
Mm9::chr1:56928204..56928208,-p@chr1:56928204..56928208
-
Mm9::chr1:56928531..56928535,-p@chr1:56928531..56928535
-
Mm9::chr1:56955934..56955944,-p@chr1:56955934..56955944
-
Mm9::chr1:57026671..57026694,-p@chr1:57026671..57026694
-
Mm9::chr1:57028111..57028122,-p9@Satb2
Mm9::chr1:57028125..57028149,-p2@Satb2
Mm9::chr1:57028157..57028173,-p3@Satb2
Mm9::chr1:57028182..57028191,-p11@Satb2
Mm9::chr1:57028295..57028349,+p1@9130024F11Rik
Mm9::chr1:57028594..57028604,-p10@Satb2
Mm9::chr1:57028606..57028625,-p4@Satb2
Mm9::chr1:57028877..57028888,+p@chr1:57028877..57028888
+
Mm9::chr1:57029024..57029050,+p@chr1:57029024..57029050
+
Mm9::chr1:57029399..57029433,+p@chr1:57029399..57029433
+
Mm9::chr1:57030876..57030880,+p@chr1:57030876..57030880
+
Mm9::chr2:151906844..151906873,+p3@Scrt2
Mm9::chr2:61642558..61642595,+p3@Tbr1
Mm9::chr2:61642631..61642684,+p1@Tbr1
Mm9::chr2:61642695..61642702,+p5@Tbr1
Mm9::chr2:61642743..61642758,+p2@Tbr1
Mm9::chr2:61642814..61642823,+p@chr2:61642814..61642823
+
Mm9::chr2:61643033..61643053,+p@chr2:61643033..61643053
+
Mm9::chr2:61643081..61643095,+p@chr2:61643081..61643095
+
Mm9::chr2:61643097..61643110,+p@chr2:61643097..61643110
+
Mm9::chr2:61650563..61650574,+p@chr2:61650563..61650574
+
Mm9::chr2:61651001..61651017,+p@chr2:61651001..61651017
+
Mm9::chr2:6792577..6792584,+p@chr2:6792577..6792584
+
Mm9::chr2:6806151..6806167,-p28@Celf2
Mm9::chr2:6806188..6806236,-p19@Celf2
Mm9::chr2:6806268..6806283,-p21@Celf2
Mm9::chr2:6806301..6806314,-p22@Celf2
Mm9::chr2:75086522..75086539,+p@chr2:75086522..75086539
+
Mm9::chr3:17954233..17954249,+p1@Bhlhe22
Mm9::chr3:17954392..17954407,+p2@Bhlhe22
Mm9::chr3:84108569..84108582,-p22@Trim2
Mm9::chr3:84108600..84108614,-p13@Trim2
Mm9::chr3:84108655..84108675,-p12@Trim2
Mm9::chr4:102997512..102997558,+p@chr4:102997512..102997558
+
Mm9::chr4:22413708..22413719,-p@chr4:22413708..22413719
-
Mm9::chr4:22413749..22413760,-p@chr4:22413749..22413760
-
Mm9::chr4:82138721..82138755,-p@chr4:82138721..82138755
-
Mm9::chr4:82144326..82144337,-p@chr4:82144326..82144337
-
Mm9::chr4:82145196..82145229,-p7@Nfib
Mm9::chr4:82145232..82145259,-p9@Nfib
Mm9::chr4:82155488..82155496,+p@chr4:82155488..82155496
+
Mm9::chr4:82879069..82879081,-p8@Ttc39b
Mm9::chr5:90312346..90312368,-p2@Adamts3
Mm9::chr6:144152590..144152602,-p22@Sox5
Mm9::chr6:144152648..144152680,-p5@Sox5
Mm9::chr6:144152701..144152714,-p24@Sox5
Mm9::chr6:144157869..144157876,-p26@Sox5
Mm9::chr6:144157880..144157889,-p25@Sox5
Mm9::chr6:144157893..144157905,-p14@Sox5
Mm9::chr6:144157924..144157955,-p2@Sox5
Mm9::chr6:144157960..144157967,-p20@Sox5
Mm9::chr6:144157968..144157989,-p7@Sox5
Mm9::chr6:144157991..144158007,-p9@Sox5
Mm9::chr6:144158153..144158167,-p19@Sox5
Mm9::chr6:144158183..144158210,-p11@Sox5
Mm9::chr6:144158267..144158282,-p16@Sox5
Mm9::chr6:55628519..55628533,-p@chr6:55628519..55628533
-
Mm9::chr6:55628542..55628563,-p@chr6:55628542..55628563
-
Mm9::chr6:55629052..55629066,-p@chr6:55629052..55629066
-
Mm9::chr6:55629608..55629628,-p@chr6:55629608..55629628
-
Mm9::chr6:55631042..55631102,-p1@Neurod6
Mm9::chr6:55631181..55631195,+p@chr6:55631181..55631195
+
Mm9::chr6:55631202..55631233,+p@chr6:55631202..55631233
+
Mm9::chr6:55631251..55631265,-p2@Neurod6
Mm9::chr6:55631282..55631299,+p@chr6:55631282..55631299
+
Mm9::chr6:55631324..55631335,-p3@Neurod6
Mm9::chr7:86531829..86531867,-p2@Rlbp1
Mm9::chr7:86680883..86680947,+p@chr7:86680883..86680947
+
Mm9::chr8:71658592..71658596,-p@chr8:71658592..71658596
-
Mm9::chr8:71708076..71708139,-p1@ENSMUST00000172413
p1@uc009lxb.1
Mm9::chr8:8621291..8621320,-p@chr8:8621291..8621320
-
Mm9::chr9:107407918..107407940,+p5@Cacna2d2
Mm9::chr9:118394263..118394288,+p@chr9:118394263..118394288
+
Mm9::chr9:120954001..120954018,-p6@Ulk4
Mm9::chr9:58046928..58046939,-p@chr9:58046928..58046939
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0065007biological regulation6.92642685468837e-08
GO:0006355regulation of transcription, DNA-dependent9.84396779962737e-08
GO:0006351transcription, DNA-dependent9.84396779962737e-08
GO:0032774RNA biosynthetic process9.84396779962737e-08
GO:0003677DNA binding9.84396779962737e-08
GO:0019222regulation of metabolic process9.84396779962737e-08
GO:0045449regulation of transcription9.84396779962737e-08
GO:0050789regulation of biological process9.84396779962737e-08
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process1.1686848142673e-07
GO:0006350transcription1.28526040306994e-07
GO:0010468regulation of gene expression1.94151723713076e-07
GO:0031323regulation of cellular metabolic process3.29084677911261e-07
GO:0050794regulation of cellular process6.13238654211701e-07
GO:0016070RNA metabolic process7.27563497338756e-07
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process1.20682343817744e-06
GO:0010467gene expression1.28229738144171e-06
GO:0043283biopolymer metabolic process3.34520698961319e-06
GO:0003676nucleic acid binding1.16785624495997e-05
GO:0003700transcription factor activity1.55499946371682e-05
GO:0007275multicellular organismal development0.00010835014899739
GO:0032501multicellular organismal process0.000115261877887468
GO:0043170macromolecule metabolic process0.000271144404853417
GO:0007420brain development0.000294810163091713
GO:0030900forebrain development0.000481132545249111
GO:0048666neuron development0.000612359123428026
GO:0007417central nervous system development0.000775517727305473
GO:0048856anatomical structure development0.000775517727305473
GO:0044238primary metabolic process0.000905910292692037
GO:0048731system development0.000915354416258053
GO:0044237cellular metabolic process0.000915354416258053
GO:0005667transcription factor complex0.0010319370587749
GO:0007399nervous system development0.00105563528805409
GO:0030182neuron differentiation0.00144262815090391
GO:0032502developmental process0.00149242453091425
GO:0007409axonogenesis0.00177430338629772
GO:0048667neuron morphogenesis during differentiation0.00208792384673866
GO:0048812neurite morphogenesis0.00208792384673866
GO:0008038neuron recognition0.00217910028963226
GO:0048699generation of neurons0.00222458909236768
GO:0005634nucleus0.00226916841375991
GO:0044451nucleoplasm part0.00262943763722978
GO:0022008neurogenesis0.00286207671032103
GO:0000904cellular morphogenesis during differentiation0.00291468213444351
GO:0005654nucleoplasm0.00309812654676973
GO:0048513organ development0.00309812654676973
GO:0007411axon guidance0.0032570022222967
GO:0031175neurite development0.0032570022222967
GO:0048869cellular developmental process0.00353719730615721
GO:0030154cell differentiation0.00353719730615721
GO:0031981nuclear lumen0.00691639763886853
GO:0032990cell part morphogenesis0.00937243738238856
GO:0048858cell projection morphogenesis0.00937243738238856
GO:0030030cell projection organization and biogenesis0.00937243738238856
GO:0043233organelle lumen0.0117109348003719
GO:0031974membrane-enclosed lumen0.0117109348003719
GO:0031234extrinsic to internal side of plasma membrane0.0126582396021272
GO:0031017exocrine pancreas development0.0126582396021272
GO:0045780positive regulation of bone resorption0.0126582396021272
GO:000550211-cis retinal binding0.0126582396021272
GO:0007610behavior0.014656350765791
GO:0045595regulation of cell differentiation0.0167368999207396
GO:0030902hindbrain development0.0168607545440724
GO:0050808synapse organization and biogenesis0.0179072174004843
GO:0008037cell recognition0.0179072174004843
GO:0016199axon midline choice point recognition0.0226121789953236
GO:0021985neurohypophysis development0.0226121789953236
GO:0040014regulation of multicellular organism growth0.0237680273215628
GO:0006357regulation of transcription from RNA polymerase II promoter0.0262744348725975
GO:0035264multicellular organism growth0.0306397961167397
GO:0021854hypothalamus development0.0306397961167397
GO:0014002astrocyte development0.0306397961167397
GO:0021979hypothalamus cell differentiation0.0306397961167397
GO:0017074procollagen N-endopeptidase activity0.0306397961167397
GO:0006366transcription from RNA polymerase II promoter0.0346492066172554
GO:0044428nuclear part0.0353018013867202
GO:0016198axon choice point recognition0.0386979496977745
GO:0060024rhythmic synaptic transmission0.0386979496977745
GO:0032989cellular structure morphogenesis0.0441591472987605
GO:0000902cell morphogenesis0.0441591472987605
GO:0004994somatostatin receptor activity0.0459446533668452
GO:0016188synaptic vesicle maturation0.0459446533668452



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron of cerebral cortex1.87e-106

Uber Anatomy
Ontology termp-valuen
brain grey matter1.47e-2829
regional part of telencephalon1.47e-2829
telencephalon1.47e-2829
cerebral cortex9.04e-2521
cerebral hemisphere9.04e-2521
pallium9.04e-2521
gray matter3.97e-2334
regional part of forebrain6.73e-2139
forebrain6.73e-2139
future forebrain6.73e-2139
anterior neural tube3.65e-2040
regional part of cerebral cortex7.12e-1917
pre-chordal neural plate1.57e-1849
brain2.10e-1747
future brain2.10e-1747
regional part of brain1.92e-1646
occipital lobe7.12e-1510
visual cortex7.12e-1510
neocortex7.12e-1510
regional part of nervous system7.83e-1454
neural tube1.32e-1352
neural rod1.32e-1352
future spinal cord1.32e-1352
neural keel1.32e-1352
neurectoderm4.00e-1264
neural plate4.00e-1264
presumptive neural plate4.00e-1264
central nervous system8.04e-1073
ecto-epithelium1.34e-0973
nervous system2.44e-0975
ectoderm-derived structure2.28e-0795
ectoderm2.28e-0795
presumptive ectoderm2.28e-0795
corpus striatum6.15e-075
striatum6.15e-075
ventral part of telencephalon6.15e-075
future corpus striatum6.15e-075


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.263823
MA0004.10.0012989
MA0006.10.231218
MA0007.10.0505522
MA0009.10.682931
MA0014.11.13338
MA0017.10.0148939
MA0019.10.257204
MA0024.10.0637932
MA0025.10.275935
MA0027.11.19613
MA0028.10.00173642
MA0029.10.298051
MA0030.10.309118
MA0031.10.437829
MA0038.11.12383
MA0040.10.442355
MA0041.10.236508
MA0042.10.198109
MA0043.10.1509
MA0046.10.262558
MA0048.10.117703
MA0050.11.70471
MA0051.19.45511
MA0052.10.0982979
MA0055.10.184004
MA0056.10
MA0057.13.95797
MA0058.18.56955e-05
MA0059.10.00585197
MA0060.10.123981
MA0061.10.393186
MA0063.10
MA0066.10.812649
MA0067.10.403548
MA0068.14.41113
MA0069.12.44324
MA0070.12.90813
MA0071.10.727761
MA0072.10.087824
MA0073.123.4069
MA0074.10.202424
MA0076.13.10463e-05
MA0077.10.380895
MA0078.10.263505
MA0081.10.130288
MA0083.10.0381923
MA0084.10.330537
MA0087.10.285193
MA0088.10.239954
MA0089.10
MA0090.10.000553603
MA0091.10.315315
MA0092.13.01792
MA0093.15.68504e-05
MA0095.10
MA0098.10
MA0100.10.180803
MA0101.10.0169289
MA0103.10.000468985
MA0105.12.95188
MA0106.10.634559
MA0107.10.0317563
MA0108.20.162931
MA0109.10
MA0111.10.00312008
MA0113.10.00599876
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MA0117.10.55926
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MA0122.10.333937
MA0124.10.339763
MA0125.10.259154
MA0130.10
MA0131.10.131903
MA0132.10
MA0133.10
MA0135.11.10127
MA0136.10.00280062
MA0139.10.0520241
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MA0141.10.0304941
MA0142.10.108778
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MA0144.10.000460659
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MA0147.10.00447681
MA0148.10.0798835
MA0149.10.176959
MA0062.24.46449e-08
MA0035.20.108847
MA0039.20.0634062
MA0138.20.123621
MA0002.20.0828069
MA0137.20.0286424
MA0104.20.00803835
MA0047.20.184772
MA0112.20.531624
MA0065.20.90439
MA0150.10.0245787
MA0151.10
MA0152.10.302889
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MA0156.10.000603905
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MA0161.10
MA0162.19.64691
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MA0080.20.00126785
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MA0099.20.117275
MA0079.237.2136
MA0102.20.369479
MA0258.10.582767
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MA0442.10