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<html>
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text-align:left;
text-align:left;
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rexp_median_data.push([rexp_sample[i1], rexp_median_values[i1]]);
rexp_median_data.push([rexp_sample[i1], rexp_median_values[i1]]);
}
}
    $('#coexpression_dpi_cluster_scores_median_table').dataTable({
  var coexpression_dpi_cluster_scores_table =  $('#coexpression_dpi_cluster_scores_median_table').DataTable({
"sScrollY": "300px",
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"bScrollCollapse": true,
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lengthMenu: [[10, 50, -1], [10, 50, "All"]],
"aoColumns": [{ "sTitle": "FF samples",  "bSortable": false, "fnRender": function(obj) {
data: rexp_median_data,
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columns: [{ title: "FF samples",  orderable: false, render: function ( data, type, row, meta ) {
var elems = id.split('.');
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} },{ "sTitle": "Score", "sType": "numeric" }],
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                  return numb.toFixed(2) ;
} }],
order: [[ 1, "desc" ]],
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// ontology enrichment table
// ontology enrichment table
$('.enrichment_list').dataTable({
 
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"bScrollCollapse": true,
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order: [[ 1, "asc" ]]
});
});


// ffcp list
// ffcp list
$('.ffcp_list').dataTable();
var ffcp_list_table=$('.ffcp_list').DataTable({
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lengthMenu: [[10, 25, 50, 100], [10, 25, 50, 100]],
order: [[ 0, "asc" ]]
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} );
} );
</script>
</script>
</html>
</html>
 
<br>


== Phase1 CAGE Peaks ==
== Phase1 CAGE Peaks ==
{{#ask:[[Category:FFCP]][[FFCP_PHASE2:+]][[Species::Mouse (Mus musculus)]][[MCL_coexpression_id::{{PAGENAME}}]]|?Short_description|format=ttable|class=ffcp_list stripe cell-border order-column compact|limit=20000}}
<br>


{{#ask:[[Category:FFCP]][[Species::Mouse (Mus musculus)]][[MCL_coexpression_id::{{PAGENAME}}]]|?Short_description|format=ttable|class=ffcp_list|limit=20000}}
{{Fontsize|3|Enriched pathways on this co-expression cluster}}{{#info:<b>Summary:</b>
 
<br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont
 
<br>
== GOStat results on Coexpression cluster  ==
<br>link to source dataset
{{#info:The results for GOStat analysis on co-expressed clusters("All" category). <br>Analyst: Erik Arner}}
<br>[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Co-expression_clusters/mm9_co-expression_modules.tar.gz  data]
}}
<br>
----
{{#if:{{{gostat_on_MCL_coexpression}}}|
{{#if:{{{gostat_on_MCL_coexpression}}}|
<html>
<html>
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// GOstat results table start
// GOstat results table start
     var oTable =  $('#gostat_table').dataTable({
     var oTable =  $('#gostat_table').DataTable({
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lengthMenu: [[10, 50, -1], [10, 50, "All"]],
columnDefs: [ { type: "html-num", targets: [2],render: function ( data, type, row, meta ) {
                  var num =data;
                  return exp_converter(num,2,"e");
} }],
order: [[2,'asc']]
});
});


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$('#gostat_table_export_tool').before( oTableTools.dom.container );
// GOstat results table end
// GOstat results table end
});
});
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</html>
</html>


 
<table id="gostat_table" class="stripe cell-border order-column compact"><html><thead></html><tr><th>GO ID</th><th>GO name</th><th>FDR corrected p-value</th></tr><html></thead><tbody></html>
<span id="gostat_table_export_tool"></span>
<table id="gostat_table"><html><thead></html><tr><th>GO ID</th><th>GO name</th><th>FDR corrected p-value</th></tr><html></thead><tbody></html>
<tr>
<tr>
{{#arraymap:{{{gostat_on_MCL_coexpression}}}|!|$
{{#arraymap:{{{gostat_on_MCL_coexpression}}}|!|$
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|no results for this coexpression
|no results for this coexpression
}}
}}
 
<br><br>
 
{{Fontsize|3|Relative expression of the co-expression cluster over median }}{{#info: <br>Analyst: }}
 
----
== Relative expression of the co-expression cluster -Median- ==
<div id="relative_exp_of_coexp_table_button"></div><br>
{{#info: <br>Analyst: }}
<table id="coexpression_dpi_cluster_scores_median_table" class="stripe cell-border order-column compact"></table>
<table id="coexpression_dpi_cluster_scores_median_table"></table>
{{#array_recordprops:coexpression_dpi_cluster_scores_median
{{#array_recordprops:coexpression_dpi_cluster_scores_median
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|12158-128G7;12533,11850-124I5;13242,11851-124I6;13233,11848-124I3;13542,11849-124I4;13197,11852-124I7;13236,11853-124I8;13210,11818-124E9;13221,11816-124E7;13219,11820-124F2;13226,11815-124E6;13218,11819-124F1;13225,11813-124E4;13217,11817-124E8;13220,11774-124A1;13079,11776-124A3;13213,11778-124A5;13506,11775-124A2;13212,11777-124A4;13214,11779-124A6;13201,10001-101A3;10609,12972-138H2;11058,12988-138I9;12980,10262-104D1;13211,10263-104D2;13200,11845-124H9;13228,11846-124I1;13231,11847-124I2;13240,10252-104B9;13199,10253-104C1;13232,10260-104C8;13234,13063-139I3;12449,13129-140G6;12668,13195-141E9;12770,12228-129F5;12555,12229-129F6;12556,12230-129F7;12557,12159-128G8;12539,12161-128H1;12198,12163-128H3;12542,12160-128G9;12540,12162-128H2;12541,12164-128H4;12543,11484-119D8;11055,11485-119D9;11056,11299-117B3;11297,11708-123B7;13077,11550-120C2;12076,11709-123B8;12129,11551-120C3;12077,11552-120C4;12078,11633-122C4;12107,11856-125A2;13531,11854-124I9;13509,11855-125A1;13511,11711-123C1;12355,11729-123E1;12356,11634-122C5;12353,11713-123C3;12131,11731-123E3;12357,11636-122C7;12108,11716-123C6;12132,11639-122D1;12109,11717-123C7;12628,11735-123E7;12633,11640-122D2;12616,11718-123C8;12629,11736-123E8;12634,11724-123D5;12025,11742-123F5;11947,11647-122D9;12112,11738-123F1;12635,11643-122D5;12618,11721-123D2;12133,11739-123F2;12359,11644-122D6;12110,11722-123D3;12631,11740-123F3;12636,11645-122D7;12619,11723-123D4;12134,11741-123F4;12360,11646-122D8;12111,11489-119E4;12612,11490-119E5;12614,11770-123I6;12643,11725-123D6;12632,11743-123F6;12638,11648-122E1;12113,11728-123D9;12507,11746-123F9;12573,11830-124G3;13209,11825-124F7;13196,11714-123C4;13078,11637-122C8;12615,11822-124F4;13090,11824-124F6;13091,10003-101A7;10611,12338-130I7;11939,12460-132E3;13275,12582-133I8;13324,12157-128G6;12532,12971-138H1;13407,12987-138I8;13408,13003-139B6;13409,13367-143G1;13739,13368-143G2;13740,13369-143G3;13741,10008-101B6;10613,1063-29H9;10475,49-24D7;10508,406-44C5;11038,1254-43D6;11004,1263-45I1;11043,1262-18F5;11026,1311-23C1;11191,1377-27I3;11223,583-22A8;10488,46-23H1;10498,56-12G2;10483,1985-43F5;11227,1525-43A6;11225,1350-25C3;11195,37-13H4;10467,15-8B2;10494,1395-42I2;11135,36-18H7;10468,12122-128C7;12550,12125-128D1;12203,12128-128D4;12551,16-22A4;10501,19-21D8;10487,630-43F1;11226,12-14D5;10473,1392-42F2;11107,20-12F2;10482,1388-42B2;11201,1310-23B1;11218,1387-42A2;11199,58-23B2;10490,31-12G4;10484,345-16C6;11016,399-16E2;10521,426-16C9;10593,1261-18D4;11023,633-15C6;11207,1532-43E7;11140,1551-44G8;11205,777-19A2;11188,335-25E2;10596,359-14H2;10600,384-1E2;10589,413-26A8;10577,437-20E7;11007,1517-43C4;10598,1520-43B5;11008,1564-45I6;11044,12123-128C8;12206,12126-128D2;12202,12129-128D5;11928,331-24E9;10586,353-12F5;11015,376-3I9;11013,403-26D4;10597,431-16C8;11017,457-17C6;11021,479-18E5;11025,1283-20G3;11030,639-21E3;11213,1349-25I2;11221,749-24G1;11118,782-15G1;11209,821-26I6;11127,1351-25D3;11196,1390-42D2;11202,13-16E8;10478,627-43G1;11228,860-29I3;10506,178-9A3;10496,1251-16I5;11019,381-16D5;11010,976-16D8;10602,463-22H4;10585,482-18D3;10582,1289-20F7;10526,644-26D1;11126,1322-23E9;11192,688-20B8;11102,720-20F2;11095,755-23A5;11098,827-18D1;11187,1352-25E3;11121,1384-42G1;11131,411-4I9;10606,434-16F8;10997,464-22A5;10584,483-18I2;11028,1288-20C7;11001,646-21G7;11214,758-6D5;11206,832-19I1;11113,1353-25F3;11122,1385-42H1;11203,508-5B2;10466,355-15F8;10601,378-3H6;10524,409-16E1;10594,433-16D7;10520,462-17F5;10523,481-18A3;10510,499-43G4;10579,641-24F4;11117,1345-25G2;11123,684-20A8;11101,716-20H2;11103,751-24B9;11115,823-25A3;11220,1368-26H1;11198,1382-42D1;11106,28-22B1;10474,354-16G2;10522,404-26F8;10604,432-17C5;11020,458-17B6;10998,480-44A6;10605,1287-20I6;10583,640-42C6;11224,683-20E5;11212,715-19A3;11111,750-23E6;11219,822-18A4;11109,1359-25C7;11119,1394-42H2;11133,3560-170A1;11457,3632-171A1;11532,595-22B6;10480,588-5H2;10476,17-12C2;10477,1396-42A3;11200,1830-49C7;11093,1389-42C2;11129,11810-124E1;13087,11811-124E2;13088,11812-124E3;13089,11807-124D7;13084,11808-124D8;13085,11809-124D9;13086,11804-124D4;13081,11805-124D5;13082,11806-124D6;13083,18-22I9;10489,91-2I7;10507,505-44H7;11040,1299-22I4;11217,988-6G6;10500,34-16E4;10486,405-44F4;11012,1556-45F2;11042,460-26E5;11003,1558-45G3;10599,1535-43I7;10580,645-26G9;11105,1531-43D7;11138,1539-43D8;11139,787-43B6;11136,1555-45E2;11094,1548-44H5;11182,21-1G8;10493,346-16E6;11018,370-44C7;11009,398-44A5;11037,427-16B9;10592,449-43F6;11036,1265-44F5;11039,1308-22E9;11190,539-13I7;10472,577-18G3;10464,859-1F8;10470,30-1C3;10492,650-25G4;11124,662-22H3;11215,693-20I5;11097,762-6C4;11108,790-21I1;11114,24-13C9;10505,25-2G2;10465,461-43C1;11035,1271-21F2;11011,752-24D1;11116,824-19H1;11112,1354-25G3;11099,12121-128C6;12534,12124-128C9;12535,12127-128D3;12536,33-1H6;10503,356-43E3;10588,1252-16G8;10603,459-17D4;11022,1035-18D5;11006,1286-20C6;10999,1340-24B8;11193,718-18A9;11210,1355-25E4;11104,1386-42I1;11134,59-29C1;10469,57-7G5;10504,389-23F5;11031,443-27C5;11034,470-26G5;11033,486-18I5;11029,503-18G5;11027,1300-22B7;11189,726-26I4;11222,763-44D9;11204,839-18H3;11110,1391-42E2;11130,38-12B5;10471,402-44I4;11041,430-45I2;11005,456-26C5;11002,478-18C1;10581,1273-19G4;10595,1541-43F8;11181,2104-43C7;11137,681-26C4;11197,713-19D3;11211,748-24E4;11194,820-7A2;11186,1362-25G7;11125,1393-42G2;11132,32-1B4;10499,13297-142H3;13526,13283-142F7;13481,13290-142G5;13519,879-12E4;10481,590-15F5;10497,92-27E5;10509,89-27D5;10502,51-27F8;10491,10235-104A1;13031,10236-104A2;13032,10237-104A3;13033,10349-105D7;13820,10238-104A4;13034,10239-104A5;13035,10240-104A6;13036,10241-104A7;13037,10242-104A8;13038,10243-104A9;13039,324-5I8;11014,857-27C9;10587,372-23H2;10512,420-27D2;10578,395-14B1;10519,453-14F2;10514,3139-67G5;10479,3139-67G5;10495,3139-67G5;10511,3139-67G5;10527,3139-67G5;10591,3139-67G5;10607,3139-67G5;10623,3139-67G5;10639,3139-67G5;10655,3139-67G5;10725,3139-67G5;10749,3139-67G5;10840,3139-67G5;10856,3139-67G5;10880,3139-67G5;11000,3139-67G5;11024,3139-67G5;11032,3139-67G5;11048,3139-67G5;11072,3139-67G5;11080,3139-67G5;11096,3139-67G5;11120,3139-67G5;11128,3139-67G5;11184,3139-67G5;11208,3139-67G5;11216,3139-67G5;11246,3139-67G5;11278,490-9F9;10513,475-3I5;10517,493-3B3;10516,657-19C2;10525,659-23C6;10576,692-21D1;10515,761-6B4;10518
|{{{coexpression_dpi_cluster_scores_median}}}
|{{{coexpression_dpi_cluster_scores_median}}}
}}
}}
 
<br><br>
 
{{Fontsize|3|Enriched sample ontology terms on this co-expression cluster}}{{#info:<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji
== Ontology enrichment ==
<br><br>links to source dataset<br><br>
{{#info: <br>Analyst: }}
{{#if:{{{ontology_enrichment_celltype}}}|[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Sample_ontology_enrichment_of_coexpression_clusters/mcl_mm9_clusters_relative_exp_enrichment_cell_type.txt.gz  cell_data]|}}<br>
{{#if:{{{ontology_enrichment_uberon}}}|[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Sample_ontology_enrichment_of_coexpression_clusters/mcl_mm9_clusters_relative_exp_enrichment_uberon.txt.gz  uberon_data]|}}<br>
{{#if:{{{ontology_enrichment_disease}}}|[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Sample_ontology_enrichment_of_coexpression_clusters/mcl_mm9_clusters_relative_exp_enrichment_disease.txt.gz  disease_data]|}}<br>
}}
----
{{#if:{{{ontology_enrichment_celltype}}}|
{{#if:{{{ontology_enrichment_celltype}}}|
<div style="float:left;width:33%;">
<div style="float:left;width:33%;">
<table class="enrichment_list"><caption class="table_title">Cell Type</caption><html><thead></html>
<table class="enrichment_list stripe cell-border order-column compact" id="enrichment_list_cell_type_table"><caption class="table_title">Cell Type</caption><html><thead></html>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<html></thead><tbody></html><tr><td>
<html></thead><tbody></html>
{{#arraymap:{{{ontology_enrichment_celltype}}}|;|$
{{#arraymap:{{{ontology_enrichment_celltype}}}|;|$
|{{#set:MCL_coexpression_mm9_ontology_enrichment_celltype={{#replace:$|!|;}}}}[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}
|{{#ifexist:{{#explode:$|!|0}}|<tr><td>[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}</td></tr>| }}
|</td></tr><tr><td>}}
|
</td></tr>
}}
<html></tbody></html></table>
<html></tbody></html></table>
</div>
</div>
}}{{#if:{{{ontology_enrichment_uberon}}}|
}}{{#if:{{{ontology_enrichment_uberon}}}|
<div style="float:left;width:33%;">
<div style="float:left;width:33%;">
<table class="enrichment_list"><caption class="table_title">Uber Anatomy</caption><html><thead></html>
<table class="enrichment_list stripe cell-border order-column compact" id="enrichment_list_uberon_table"><caption class="table_title">Uber Anatomy</caption><html><thead></html>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<html></thead><tbody></html><tr><td>
<html></thead><tbody></html>
{{#arraymap:{{{ontology_enrichment_uberon}}}|;|$
{{#arraymap:{{{ontology_enrichment_uberon}}}|;|$
|{{#set:MCL_coexpression_mm9_ontology_enrichment_uberon={{#replace:$|!|;}}}}[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}
|{{#ifexist:{{#explode:$|!|0}}|<tr><td>[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}</td></tr>| }}
|</td></tr><tr><td>}}
|}}
</td></tr>
<html></tbody></html></table>
<html></tbody></html></table>
</div>
</div>
}}{{#if:{{{ontology_enrichment_disease}}}|
}}{{#if:{{{ontology_enrichment_disease}}}|
<div style="float:left;width:33%;">
<div style="float:left;width:33%;">
<table class="enrichment_list"><caption class="table_title">Disease</caption><html><thead></html>
<table class="enrichment_list stripe cell-border order-column compact" id="enrichment_list_disease_table"><caption class="table_title">Disease</caption><html><thead></html>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<tr><th>Ontology term</th><th>p-value</th><th>n</th></tr>
<html></thead><tbody></html><tr><td>
<html></thead><tbody></html>
{{#arraymap:{{{ontology_enrichment_disease}}}|;|$
{{#arraymap:{{{ontology_enrichment_disease}}}|;|$
|{{#set:MCL_coexpression_mm9_ontology_enrichment_disease={{#replace:$|!|;}}}}[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}
|{{#ifexist:{{#explode:$|!|0}}|<tr><td>[[{{#explode:$|!|0}}|{{#show:{{#explode:$|!|0}}|?name}}]]</td><td>{{#explode:$|!|1}}</td><td>{{#explode:$|!|2}}</td></tr>| }}
|</td></tr><tr><td>}}
|}}
</td></tr>
<html></tbody></html></table>
<html></tbody></html></table>
</div>
</div>
}}
}}
<div style="clear:both;"></div>
<div style="clear:both;"></div>
 
<br>
 
{{Fontsize|3|TFBS overrepresentation}}{{#info:<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>
== TFBS overrepresentation ==
link to source data <br> Novel motifs <br>
{{#info:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <br>Analyst: Michiel de Hoon}}
[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Co-expression_clusters/mm9.novel_motif.coexpression_clusters_overrepresentation.txt.gz data] <br>
<br> Jaspar motifs <br>
[//fantom.gsc.riken.jp/5/datafiles/phase1.1/extra/Co-expression_clusters/mm9.KNOWN_JASPAR_130.coexpression_clusters_overrepresentation.txt.gz data]
}}
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[[Category:MCL_coexpression_mm9]]
[[Category:MCL_coexpression_mm9]]

Revision as of 16:16, 16 January 2020


Phase1 CAGE Peaks


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
{{{gostat_on_MCL_coexpression}}}



Relative expression of the co-expression cluster over median <br>Analyst:



"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}