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|namespace=
|namespace=
|def="the outermost of the three layers of the meninges surrounding the brain and spinal cord. The other two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid." [Wikipedia:Dura_mater]
|def="the outermost of the three layers of the meninges surrounding the brain and spinal cord. The other two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid." [Wikipedia:Dura_mater]
|xref=BTO:0001637;;EMAPA:17776;;EV:0100313;;FMA:9592;;GAID:691;;MA:0001115;;MESH:A.08.186.566.395;;ncithesaurus:Dura_Mater;;NIF_GrossAnatomy:nlx_anat_090206;;OpenCyc:Mx4rvvmzqZwpEbGdrcN5Y29ycA;;SCTID:362301008
|xref=BTO:0001637;;EMAPA:17776;;EV:0100313;;FMA:9592;;GAID:691;;http://upload.wikimedia.org/wikipedia/commons/8/8e/Meninges-en.svg;;MA:0001115;;MESH:A.08.186.566.395;;ncithesaurus:Dura_Mater;;NIF_GrossAnatomy:nlx_anat_090206;;OpenCyc:Mx4rvvmzqZwpEbGdrcN5Y29ycA;;SCTID:362301008
|is_a=UBERON:0002360
|is_a=UBERON:0002360;;UBERON:0004120;;UBERON:0010314
|synonym="dura" RELATED [BTO:0001637];;"dura mater of neuraxis" EXACT [];;"pachymeninges" EXACT [NIF_GrossAnatomy:nlx_anat_090206]
|synonym="dura" RELATED [BTO:0001637];;"dura mater of neuraxis" EXACT [];;"pachymeninges" EXACT [NIF_GrossAnatomy:nlx_anat_090206]
|comment=
|comment=Function notes: capable of inducing chondrogenesis - requires contact with an epithelium - PMID:16496288. AO notes: in ncit this is divided into periosteal layer and meningeal layer
|alt_id=UBERON:FMA_9592-MA_0001115
|alt_id=UBERON:FMA_9592-MA_0001115
|disjoint_from=
|disjoint_from=
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|obo_creation_date=
|obo_creation_date=
|subset=organ_slim;;uberon_slim
|subset=organ_slim;;uberon_slim
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=UBERON:0007647;;UBERON:0010115
|develops_from=
|has_quality=
|has_quality=
|located_in=
|located_in=
|part_of=UBERON:0002360
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.obo.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;RO:0002161 NCBITaxon:32443
|is_obsolete=
|is_obsolete=
|preceded_by=
|preceded_by=
}}
}}

Revision as of 17:02, 26 June 2012

Name:dura mater
Definition:"the outermost of the three layers of the meninges surrounding the brain and spinal cord. The other two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid." [Wikipedia:Dura_mater]
Xrefs:
links:

BTO:0001637
EMAPA:17776
EV:0100313
FMA:9592
GAID:691
[1]
MA:0001115
MESH:A.08.186.566.395
ncithesaurus:Dura_Mater
NIF_GrossAnatomy:nlx_anat_090206
OpenCyc:Mx4rvvmzqZwpEbGdrcN5Y29ycA

SCTID:362301008
Synonyms: "dura" RELATED [BTO:0001637]
"dura mater of neuraxis" EXACT []
"pachymeninges" EXACT [NIF_GrossAnatomy:nlx_anat_090206]
Comments:Function notes: capable of inducing chondrogenesis - requires contact with an epithelium - PMID:16496288. AO notes: in ncit this is divided into periosteal layer and meningeal layer
Alt_id: UBERON:FMA_9592-MA_0001115
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002360(meninx),UBERON:0004120(mesoderm-derived structure),UBERON:0010314(structure with developmental contribution from neural crest)



Children

derives from:FF:0010041 (human dura mater - adult sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002363 (dura mater), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr5:39892092..39892099,+#_6940ad07e24a0f7893739adf99818e0ep@chr5:39892092..39892099, +
5.42e-195FFCP PHASE2:Hg19::chr3:112931366..112931373,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931366..112931373, -
5.42e-195FFCP PHASE1:Hg19::chr5:122434930..122434939,+#_6940ad07e24a0f7893739adf99818e0ep@chr5:122434930..122434939, +
5.42e-195FFCP PHASE1:Hg19::chr3:112931366..112931373,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931366..112931373, -
5.42e-195FFCP PHASE2:Hg19::chr3:112931383..112931390,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931383..112931390, -
5.42e-195FFCP PHASE2:Hg19::chr8:43349847..43349852,+#_6940ad07e24a0f7893739adf99818e0ep@chr8:43349847..43349852, +
5.42e-195FFCP PHASE1:Hg19::chr8:43349847..43349852,+#_6940ad07e24a0f7893739adf99818e0ep@chr8:43349847..43349852, +
5.42e-195FFCP PHASE1:Hg19::chr10:79398656..79398666,-#_6940ad07e24a0f7893739adf99818e0ep25@KCNMA1
5.42e-195FFCP PHASE2:Hg19::chr2:217560615..217560623,-#_6940ad07e24a0f7893739adf99818e0ep73@IGFBP5
5.42e-195FFCP PHASE2:Hg19::chr4:154712764..154712772,-#_6940ad07e24a0f7893739adf99818e0ep@chr4:154712764..154712772, -
5.42e-195FFCP PHASE2:Hg19::chr2:45234395..45234400,-#_6940ad07e24a0f7893739adf99818e0ep@chr2:45234395..45234400, -
5.42e-195FFCP PHASE1:Hg19::chr3:112931383..112931390,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931383..112931390, -
5.42e-195FFCP PHASE1:Hg19::chr10:78078199..78078208,+#_6940ad07e24a0f7893739adf99818e0ep8@C10orf11
5.42e-195FFCP PHASE2:Hg19::chr3:112931404..112931414,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931404..112931414, -
5.42e-195FFCP PHASE2:Hg19::chr8:48651813..48651830,-#_6940ad07e24a0f7893739adf99818e0ep14@CEBPD
5.42e-195FFCP PHASE1:Hg19::chr8:48651813..48651830,-#_6940ad07e24a0f7893739adf99818e0ep14@CEBPD
5.42e-195FFCP PHASE1:Hg19::chr2:217560615..217560623,-#_6940ad07e24a0f7893739adf99818e0ep73@IGFBP5
5.42e-195FFCP PHASE1:Hg19::chr4:154712764..154712772,-#_6940ad07e24a0f7893739adf99818e0ep@chr4:154712764..154712772, -
5.42e-195FFCP PHASE1:Hg19::chr2:45234395..45234400,-#_6940ad07e24a0f7893739adf99818e0ep@chr2:45234395..45234400, -
5.42e-195FFCP PHASE1:Hg19::chr3:112931404..112931414,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931404..112931414, -
5.42e-195FFCP PHASE2:Hg19::chr10:79398656..79398666,-#_6940ad07e24a0f7893739adf99818e0ep25@KCNMA1
5.42e-195FFCP PHASE2:Hg19::chr3:112931435..112931445,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931435..112931445, -
5.42e-195FFCP PHASE2:Hg19::chr10:78078199..78078208,+#_6940ad07e24a0f7893739adf99818e0ep8@C10orf11
5.42e-195FFCP PHASE2:Hg19::chr5:39892092..39892099,+#_6940ad07e24a0f7893739adf99818e0ep@chr5:39892092..39892099, +
5.42e-195FFCP PHASE1:Hg19::chr3:112931435..112931445,-#_6940ad07e24a0f7893739adf99818e0ep@chr3:112931435..112931445, -
5.42e-195FFCP PHASE2:Hg19::chr5:122434930..122434939,+#_6940ad07e24a0f7893739adf99818e0ep@chr5:122434930..122434939, +
9.37e-99FFCP PHASE1:Hg19::chr9:23524699..23524703,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr9:23524699..23524703, -
9.37e-99FFCP PHASE2:Hg19::chr4:154711058..154711075,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr4:154711058..154711075, +
9.37e-99FFCP PHASE2:Hg19::chr1:66031903..66031907,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr1:66031903..66031907, +
9.37e-99FFCP PHASE2:Hg19::chr8:43349794..43349803,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr8:43349794..43349803, +
9.37e-99FFCP PHASE1:Hg19::chr8:43349794..43349803,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr8:43349794..43349803, +
9.37e-99FFCP PHASE1:Hg19::chr16:73094120..73094122,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr16:73094120..73094122, -
9.37e-99FFCP PHASE2:Hg19::chr7:115135068..115135092,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr7:115135068..115135092, -
9.37e-99FFCP PHASE1:Hg19::chr4:154711058..154711075,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr4:154711058..154711075, +
9.37e-99FFCP PHASE1:Hg19::chr1:66031903..66031907,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr1:66031903..66031907, +
9.37e-99FFCP PHASE2:Hg19::chr16:73094120..73094122,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr16:73094120..73094122, -
9.37e-99FFCP PHASE1:Hg19::chr7:115135068..115135092,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr7:115135068..115135092, -
9.37e-99FFCP PHASE1:Hg19::chr19:2309357..2309359,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr19:2309357..2309359, +
9.37e-99FFCP PHASE2:Hg19::chr8:72274182..72274188,-#_6f25361874e9bf1fcf76447fdddc29d8p18@EYA1
9.37e-99FFCP PHASE1:Hg19::chr8:72274182..72274188,-#_6f25361874e9bf1fcf76447fdddc29d8p18@EYA1
9.37e-99FFCP PHASE2:Hg19::chr19:2309357..2309359,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr19:2309357..2309359, +
9.37e-99FFCP PHASE2:Hg19::chr3:147794257..147794262,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr3:147794257..147794262, +
9.37e-99FFCP PHASE1:Hg19::chr3:147794257..147794262,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr3:147794257..147794262, +
9.37e-99FFCP PHASE1:Hg19::chr18:14221875..14221879,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr18:14221875..14221879, -
9.37e-99FFCP PHASE2:Hg19::chr9:23524699..23524703,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr9:23524699..23524703, -
9.37e-99FFCP PHASE2:Hg19::chr8:43349758..43349771,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr8:43349758..43349771, +
9.37e-99FFCP PHASE1:Hg19::chr8:43349758..43349771,+#_6f25361874e9bf1fcf76447fdddc29d8p@chr8:43349758..43349771, +
9.37e-99FFCP PHASE2:Hg19::chr18:14221875..14221879,-#_6f25361874e9bf1fcf76447fdddc29d8p@chr18:14221875..14221879, -
2.55e-98FFCP PHASE2:Hg19::chr11:44360838..44360846,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp@chr11:44360838..44360846, +
2.55e-98FFCP PHASE1:Hg19::chr1:65990750..65990756,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp@chr1:65990750..65990756, +
2.55e-98FFCP PHASE1:Hg19::chr11:44360838..44360846,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp@chr11:44360838..44360846, +
2.55e-98FFCP PHASE1:Hg19::chr1:183775501..183775512,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp13@RGL1
2.55e-98FFCP PHASE2:Hg19::chr1:183775501..183775512,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp13@RGL1
2.55e-98FFCP PHASE2:Hg19::chr1:65990750..65990756,+#_3ba60e4f611ef0c4c3967a6d667e5f5dp@chr1:65990750..65990756, +
1.23e-66FFCP PHASE2:Hg19::chr9:23524722..23524736,-#_43655a68e68893c3b2c8f875e3e5787fp@chr9:23524722..23524736, -
1.23e-66FFCP PHASE2:Hg19::chr2:45715445..45715482,-#_43655a68e68893c3b2c8f875e3e5787fp@chr2:45715445..45715482, -
1.23e-66FFCP PHASE1:Hg19::chr3:112931461..112931474,-#_43655a68e68893c3b2c8f875e3e5787fp@chr3:112931461..112931474, -
1.23e-66FFCP PHASE2:Hg19::chr4:26165179..26165190,+#_43655a68e68893c3b2c8f875e3e5787fp47@RBPJ
1.23e-66FFCP PHASE1:Hg19::chr9:23524722..23524736,-#_43655a68e68893c3b2c8f875e3e5787fp@chr9:23524722..23524736, -
1.23e-66FFCP PHASE2:Hg19::chr4:154711263..154711272,+#_43655a68e68893c3b2c8f875e3e5787fp@chr4:154711263..154711272, +
1.23e-66FFCP PHASE2:Hg19::chr9:23524772..23524783,-#_43655a68e68893c3b2c8f875e3e5787fp@chr9:23524772..23524783, -
1.23e-66FFCP PHASE1:Hg19::chr2:45715445..45715482,-#_43655a68e68893c3b2c8f875e3e5787fp@chr2:45715445..45715482, -
1.23e-66FFCP PHASE1:Hg19::chr4:26165179..26165190,+#_43655a68e68893c3b2c8f875e3e5787fp47@RBPJ
1.23e-66FFCP PHASE1:Hg19::chr9:23524772..23524783,-#_43655a68e68893c3b2c8f875e3e5787fp@chr9:23524772..23524783, -
1.23e-66FFCP PHASE1:Hg19::chr4:154711263..154711272,+#_43655a68e68893c3b2c8f875e3e5787fp@chr4:154711263..154711272, +
1.23e-66FFCP PHASE2:Hg19::chr3:112931461..112931474,-#_43655a68e68893c3b2c8f875e3e5787fp@chr3:112931461..112931474, -
2.39e-66FFCP PHASE1:Hg19::chr6:55740051..55740056,-#_9f155a09a08b4cb7ffaaa5284e11e98bp5@BMP5
2.39e-66FFCP PHASE2:Hg19::chr6:55740051..55740056,-#_9f155a09a08b4cb7ffaaa5284e11e98bp5@BMP5
4.66e-66FFCP PHASE1:Hg19::chr20:36979501..36979520,-#_f3d36d59a04b84f76de8f0f759b31904p@chr20:36979501..36979520, -
4.66e-66FFCP PHASE2:Hg19::chr11:44360939..44360945,+#_f3d36d59a04b84f76de8f0f759b31904p@chr11:44360939..44360945, +
4.66e-66FFCP PHASE2:Hg19::chr20:36979501..36979520,-#_f3d36d59a04b84f76de8f0f759b31904p@chr20:36979501..36979520, -
4.66e-66FFCP PHASE1:Hg19::chr11:44360939..44360945,+#_f3d36d59a04b84f76de8f0f759b31904p@chr11:44360939..44360945, +
1.46e-50FFCP PHASE2:Hg19::chr2:228028554..228028577,+#_2ceae9038bce7dc68ab03c759815c42bp@chr2:228028554..228028577, +
1.46e-50FFCP PHASE1:Hg19::chr14:61748435..61748448,-#_2ceae9038bce7dc68ab03c759815c42bp17@TMEM30B
1.46e-50FFCP PHASE1:Hg19::chr2:228028554..228028577,+#_2ceae9038bce7dc68ab03c759815c42bp@chr2:228028554..228028577, +
1.46e-50FFCP PHASE1:Hg19::chr13:100622472..100622484,-#_2ceae9038bce7dc68ab03c759815c42bp@chr13:100622472..100622484, -
1.46e-50FFCP PHASE2:Hg19::chr13:100622472..100622484,-#_2ceae9038bce7dc68ab03c759815c42bp@chr13:100622472..100622484, -
1.46e-50FFCP PHASE2:Hg19::chr14:61748435..61748448,-#_2ceae9038bce7dc68ab03c759815c42bp17@TMEM30B
1.46e-50FFCP PHASE2:Hg19::chr5:122434917..122434927,+#_2ceae9038bce7dc68ab03c759815c42bp@chr5:122434917..122434927, +
1.46e-50FFCP PHASE1:Hg19::chr5:122434917..122434927,+#_2ceae9038bce7dc68ab03c759815c42bp@chr5:122434917..122434927, +
2.42e-50FFCP PHASE2:Hg19::chr12:103218428..103218438,-#_a4a9cbd9186eed8915531509c2cb03e8p1@LINC00485
2.42e-50FFCP PHASE2:Hg19::chr10:78078276..78078291,+#_a4a9cbd9186eed8915531509c2cb03e8p7@C10orf11
2.42e-50FFCP PHASE2:Hg19::chr5:122448503..122448506,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr5:122448503..122448506, +
2.42e-50FFCP PHASE1:Hg19::chr11:44360809..44360823,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr11:44360809..44360823, +
2.42e-50FFCP PHASE2:Hg19::chr5:122425429..122425438,+#_a4a9cbd9186eed8915531509c2cb03e8p8@PRDM6
2.42e-50FFCP PHASE1:Hg19::chr5:122448503..122448506,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr5:122448503..122448506, +
2.42e-50FFCP PHASE2:Hg19::chr7:70060849..70060859,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr7:70060849..70060859, +
2.42e-50FFCP PHASE1:Hg19::chr7:70060849..70060859,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr7:70060849..70060859, +
2.42e-50FFCP PHASE1:Hg19::chr12:103218428..103218438,-#_a4a9cbd9186eed8915531509c2cb03e8p1@LINC00485
2.42e-50FFCP PHASE1:Hg19::chr5:122425429..122425438,+#_a4a9cbd9186eed8915531509c2cb03e8p8@PRDM6
2.42e-50FFCP PHASE1:Hg19::chr10:78078276..78078291,+#_a4a9cbd9186eed8915531509c2cb03e8p7@C10orf11
2.42e-50FFCP PHASE2:Hg19::chr11:44360809..44360823,+#_a4a9cbd9186eed8915531509c2cb03e8p@chr11:44360809..44360823, +
3.99e-50FFCP PHASE2:Hg19::chr5:67750872..67750876,+#_fd1ee7ce8102716e13027f771a970b21p@chr5:67750872..67750876, +
3.99e-50FFCP PHASE1:Hg19::chr5:67750872..67750876,+#_fd1ee7ce8102716e13027f771a970b21p@chr5:67750872..67750876, +
6.58e-50FFCP PHASE2:Hg19::chr11:114173606..114173612,+#_674bf034d0ae4b4b067e3b5a067d4ca0p@chr11:114173606..114173612, +
6.58e-50FFCP PHASE1:Hg19::chr14:72053507..72053516,+#_674bf034d0ae4b4b067e3b5a067d4ca0p@chr14:72053507..72053516, +
6.58e-50FFCP PHASE1:Hg19::chr11:114173606..114173612,+#_674bf034d0ae4b4b067e3b5a067d4ca0p@chr11:114173606..114173612, +
6.58e-50FFCP PHASE2:Hg19::chr14:72053507..72053516,+#_674bf034d0ae4b4b067e3b5a067d4ca0p@chr14:72053507..72053516, +
6.62e-41FFCP PHASE2:Hg19::chr1:119543994..119544001,-#_c2d85dbf2303c6d8c63b82eee85019bdp2@ENST00000439394
6.62e-41FFCP PHASE2:Hg19::chr5:39892121..39892134,+#_c2d85dbf2303c6d8c63b82eee85019bdp@chr5:39892121..39892134, +