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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0009897;external side of plasma membrane;0.00912791783016858;22163,21936!GO:0009986;cell surface;0.00912791783016858;22163,21936!GO:0050710;negative regulation of cytokine secretion;0.00912791783016858;22163!GO:0050709;negative regulation of protein secretion;0.00912791783016858;22163!GO:0043120;tumor necrosis factor binding;0.00912791783016858;22163!GO:0008517;folic acid transporter activity;0.00912791783016858;64931!GO:0005031;tumor necrosis factor receptor activity;0.00912791783016858;22163!GO:0050707;regulation of cytokine secretion;0.00912791783016858;22163!GO:0005035;death receptor activity;0.00912791783016858;22163!GO:0050663;cytokine secretion;0.00985734105678631;22163!GO:0051183;vitamin transporter activity;0.0104538964262594;64931!GO:0051184;cofactor transporter activity;0.010950800927537;64931!GO:0005542;folic acid binding;0.0126334626276267;64931!GO:0051048;negative regulation of secretion;0.0140749730015192;22163!GO:0050708;regulation of protein secretion;0.0153235624722565;22163!GO:0006915;apoptosis;0.0261885469613398;22163,21936!GO:0012501;programmed cell death;0.0261885469613398;22163,21936!GO:0009306;protein secretion;0.0261885469613398;22163!GO:0008219;cell death;0.0261885469613398;22163,21936!GO:0016265;death;0.0261885469613398;22163,21936!GO:0051046;regulation of secretion;0.0405275446485512;22163!GO:0004872;receptor activity;0.0422874158580565;22163,64931,21936!GO:0019955;cytokine binding;0.0458356463213889;22163!GO:0060089;molecular transducer activity;0.0458356463213889;22163,64931,21936!GO:0004871;signal transducer activity;0.0458356463213889;22163,64931,21936!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0009897;external side of plasma membrane;0.00912791783016858;22163,21936!GO:0009986;cell surface;0.00912791783016858;22163,21936!GO:0050710;negative regulation of cytokine secretion;0.00912791783016858;22163!GO:0050709;negative regulation of protein secretion;0.00912791783016858;22163!GO:0043120;tumor necrosis factor binding;0.00912791783016858;22163!GO:0008517;folic acid transporter activity;0.00912791783016858;64931!GO:0005031;tumor necrosis factor receptor activity;0.00912791783016858;22163!GO:0050707;regulation of cytokine secretion;0.00912791783016858;22163!GO:0005035;death receptor activity;0.00912791783016858;22163!GO:0050663;cytokine secretion;0.00985734105678631;22163!GO:0051183;vitamin transporter activity;0.0104538964262594;64931!GO:0051184;cofactor transporter activity;0.010950800927537;64931!GO:0005542;folic acid binding;0.0126334626276267;64931!GO:0051048;negative regulation of secretion;0.0140749730015192;22163!GO:0050708;regulation of protein secretion;0.0153235624722565;22163!GO:0006915;apoptosis;0.0261885469613398;22163,21936!GO:0012501;programmed cell death;0.0261885469613398;22163,21936!GO:0009306;protein secretion;0.0261885469613398;22163!GO:0008219;cell death;0.0261885469613398;22163,21936!GO:0016265;death;0.0261885469613398;22163,21936!GO:0051046;regulation of secretion;0.0405275446485512;22163!GO:0004872;receptor activity;0.0422874158580565;22163,64931,21936!GO:0019955;cytokine binding;0.0458356463213889;22163!GO:0060089;molecular transducer activity;0.0458356463213889;22163,64931,21936!GO:0004871;signal transducer activity;0.0458356463213889;22163,64931,21936!
}}

Revision as of 11:09, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr13:105078012..105078042,+p4@Adamts6
Mm9::chr13:105412781..105412798,+p@chr13:105412781..105412798
+
Mm9::chr19:10800783..10800787,-p@chr19:10800783..10800787
-
Mm9::chr2:153104456..153104461,+p@chr2:153104456..153104461
+
Mm9::chr4:155387944..155387958,+p1@Tnfrsf4
Mm9::chr4:155387967..155387981,+p2@Tnfrsf4
Mm9::chr4:155388007..155388018,+p3@Tnfrsf4
Mm9::chr4:155400315..155400334,-p@chr4:155400315..155400334
-
Mm9::chr4:155400413..155400480,+p1@Tnfrsf18
Mm9::chr6:129189762..129189789,-p@chr6:129189762..129189789
-
Mm9::chr6:129189813..129189824,-p@chr6:129189813..129189824
-
Mm9::chr6:129189844..129189851,-p@chr6:129189844..129189851
-
Mm9::chr8:84290231..84290238,+p@chr8:84290231..84290238
+
Mm9::chr9:107200546..107200558,-p@chr9:107200546..107200558
-
Mm9::chr9:107200687..107200702,+p@chr9:107200687..107200702
+
Mm9::chr9:14708434..14708444,-p8@Folr4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0009897external side of plasma membrane0.00912791783016858
GO:0009986cell surface0.00912791783016858
GO:0050710negative regulation of cytokine secretion0.00912791783016858
GO:0050709negative regulation of protein secretion0.00912791783016858
GO:0043120tumor necrosis factor binding0.00912791783016858
GO:0008517folic acid transporter activity0.00912791783016858
GO:0005031tumor necrosis factor receptor activity0.00912791783016858
GO:0050707regulation of cytokine secretion0.00912791783016858
GO:0005035death receptor activity0.00912791783016858
GO:0050663cytokine secretion0.00985734105678631
GO:0051183vitamin transporter activity0.0104538964262594
GO:0051184cofactor transporter activity0.010950800927537
GO:0005542folic acid binding0.0126334626276267
GO:0051048negative regulation of secretion0.0140749730015192
GO:0050708regulation of protein secretion0.0153235624722565
GO:0006915apoptosis0.0261885469613398
GO:0012501programmed cell death0.0261885469613398
GO:0009306protein secretion0.0261885469613398
GO:0008219cell death0.0261885469613398
GO:0016265death0.0261885469613398
GO:0051046regulation of secretion0.0405275446485512
GO:0004872receptor activity0.0422874158580565
GO:0019955cytokine binding0.0458356463213889
GO:0060089molecular transducer activity0.0458356463213889
GO:0004871signal transducer activity0.0458356463213889



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}