MCL coexpression mm9:1036

Phase1 CAGE Peaks

	Short description
Mm9::chr10:6373383..6373454,-	p1@Mthfd1l
Mm9::chr14:52817186..52817193,+	p1@ENSMUST00000143086 p1@uc007tos.1
Mm9::chr15:79913772..79913789,-	p1@Gm12816 p1@LOC674810 p1@Rpl3
Mm9::chr17:24665188..24665209,+	p1@2610019E17Rik
Mm9::chr17:24856834..24856861,-	p1@Snhg9
Mm9::chr3:123211248..123211259,-	p1@Snhg8
Mm9::chr9:88417714..88417733,-	p1@ENSMUST00000034997 p1@uc009qys.1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0044249	cellular biosynthetic process	0.00253564774886875
GO:0009257	10-formyltetrahydrofolate biosynthetic process	0.00253564774886875
GO:0003735	structural constituent of ribosome	0.00253564774886875
GO:0005840	ribosome	0.00253564774886875
GO:0009058	biosynthetic process	0.00253564774886875
GO:0009256	10-formyltetrahydrofolate metabolic process	0.00253564774886875
GO:0004329	formate-tetrahydrofolate ligase activity	0.00253564774886875
GO:0009396	folic acid and derivative biosynthetic process	0.00776329406794076
GO:0006412	translation	0.00887039156264768
GO:0030529	ribonucleoprotein complex	0.00887039156264768
GO:0006760	folic acid and derivative metabolic process	0.00887039156264768
GO:0009059	macromolecule biosynthetic process	0.0161856074324591
GO:0044444	cytoplasmic part	0.0195166510969675
GO:0006752	group transfer coenzyme metabolic process	0.0341338087604507
GO:0046483	heterocycle metabolic process	0.0389122065212837
GO:0006730	one-carbon compound metabolic process	0.0425345502092769
GO:0009108	coenzyme biosynthetic process	0.0431377310490122
GO:0051188	cofactor biosynthetic process	0.0470887349534143
GO:0043232	intracellular non-membrane-bound organelle	0.0474648560494127
GO:0043228	non-membrane-bound organelle	0.0474648560494127
GO:0006725	aromatic compound metabolic process	0.0474648560494127

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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