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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0001709;cell fate determination;0.000230308074329499;14462,232174!GO:0042445;hormone metabolic process;0.0013518082623688;14462,232174!GO:0045165;cell fate commitment;0.00137684174870896;14462,232174!GO:0032753;positive regulation of interleukin-4 production;0.00380759327233879;14462!GO:0032673;regulation of interleukin-4 production;0.00609198234583313;14462!GO:0048485;sympathetic nervous system development;0.00652694513134735;14462!GO:0042421;norepinephrine biosynthetic process;0.00652694513134735;14462!GO:0042415;norepinephrine metabolic process;0.00761435209513292;14462!GO:0048384;retinoic acid receptor signaling pathway;0.00761435209513292;232174!GO:0032633;interleukin-4 production;0.00761435209513292;14462!GO:0048483;autonomic nervous system development;0.00969046256227709;14462!GO:0042573;retinoic acid metabolic process;0.0101510787109361;232174!GO:0007140;male meiosis;0.0101510787109361;232174!GO:0009954;proximal/distal pattern formation;0.0101510787109361;232174!GO:0042423;catecholamine biosynthetic process;0.0101510787109361;14462!GO:0042136;neurotransmitter biosynthetic process;0.0123706101935708;14462!GO:0006776;vitamin A metabolic process;0.0143285785579013;232174!GO:0030522;intracellular receptor-mediated signaling pathway;0.0152232802682254;232174!GO:0001819;positive regulation of cytokine production;0.0160236271775587;14462!GO:0006775;fat-soluble vitamin metabolic process;0.0167437725060497;232174!GO:0042401;biogenic amine biosynthetic process;0.0173951736223902;14462!GO:0042398;amino acid derivative biosynthetic process;0.0182619282851489;14462!GO:0018958;phenol metabolic process;0.0182619282851489;14462!GO:0006584;catecholamine metabolic process;0.0182619282851489;14462!GO:0001817;regulation of cytokine production;0.0182619282851489;14462!GO:0042446;hormone biosynthetic process;0.02085066892257;14462!GO:0042133;neurotransmitter metabolic process;0.02085066892257;14462!GO:0042035;regulation of cytokine biosynthetic process;0.026680634111376;14462!GO:0009309;amine biosynthetic process;0.026680634111376;14462!GO:0042089;cytokine biosynthetic process;0.026680634111376;14462!GO:0042107;cytokine metabolic process;0.026680634111376;14462!GO:0006766;vitamin metabolic process;0.026680634111376;232174!GO:0030326;embryonic limb morphogenesis;0.026680634111376;232174!GO:0035113;embryonic appendage morphogenesis;0.026680634111376;232174!GO:0006576;biogenic amine metabolic process;0.026680634111376;14462!GO:0051327;M phase of meiotic cell cycle;0.026680634111376;232174!GO:0007126;meiosis;0.026680634111376;232174!GO:0051321;meiotic cell cycle;0.026680634111376;232174!GO:0035107;appendage morphogenesis;0.026680634111376;232174!GO:0035108;limb morphogenesis;0.026680634111376;232174!GO:0044271;nitrogen compound biosynthetic process;0.026680634111376;14462!GO:0048869;cellular developmental process;0.026680634111376;14462,232174!GO:0030154;cell differentiation;0.026680634111376;14462,232174!GO:0060173;limb development;0.026680634111376;232174!GO:0048736;appendage development;0.026680634111376;232174!GO:0006575;amino acid derivative metabolic process;0.0284484799788564;14462!GO:0001505;regulation of neurotransmitter levels;0.0284484799788564;14462!GO:0001816;cytokine production;0.0308517453939281;14462!GO:0048856;anatomical structure development;0.0308517453939281;14462,232174!GO:0006725;aromatic compound metabolic process;0.034315035247569;14462!GO:0007275;multicellular organismal development;0.0371332501642451;14462,232174!GO:0006417;regulation of translation;0.0382321834006277;14462!GO:0031326;regulation of cellular biosynthetic process;0.0397928047893852;14462!GO:0046914;transition metal ion binding;0.0400064471977561;14462,232174!GO:0003002;regionalization;0.0405438248376606;232174!GO:0009889;regulation of biosynthetic process;0.0419776548845426;14462!GO:0016563;transcription activator activity;0.0473309004601403;14462!GO:0007268;synaptic transmission;0.0492356523214464;14462!GO:0007283;spermatogenesis;0.0492356523214464;232174!GO:0048232;male gamete generation;0.0492356523214464;232174!GO:0048598;embryonic morphogenesis;0.0499103697559423;232174!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0001709;cell fate determination;0.000230308074329499;14462,232174!GO:0042445;hormone metabolic process;0.0013518082623688;14462,232174!GO:0045165;cell fate commitment;0.00137684174870896;14462,232174!GO:0032753;positive regulation of interleukin-4 production;0.00380759327233879;14462!GO:0032673;regulation of interleukin-4 production;0.00609198234583313;14462!GO:0048485;sympathetic nervous system development;0.00652694513134735;14462!GO:0042421;norepinephrine biosynthetic process;0.00652694513134735;14462!GO:0042415;norepinephrine metabolic process;0.00761435209513292;14462!GO:0048384;retinoic acid receptor signaling pathway;0.00761435209513292;232174!GO:0032633;interleukin-4 production;0.00761435209513292;14462!GO:0048483;autonomic nervous system development;0.00969046256227709;14462!GO:0042573;retinoic acid metabolic process;0.0101510787109361;232174!GO:0007140;male meiosis;0.0101510787109361;232174!GO:0009954;proximal/distal pattern formation;0.0101510787109361;232174!GO:0042423;catecholamine biosynthetic process;0.0101510787109361;14462!GO:0042136;neurotransmitter biosynthetic process;0.0123706101935708;14462!GO:0006776;vitamin A metabolic process;0.0143285785579013;232174!GO:0030522;intracellular receptor-mediated signaling pathway;0.0152232802682254;232174!GO:0001819;positive regulation of cytokine production;0.0160236271775587;14462!GO:0006775;fat-soluble vitamin metabolic process;0.0167437725060497;232174!GO:0042401;biogenic amine biosynthetic process;0.0173951736223902;14462!GO:0042398;amino acid derivative biosynthetic process;0.0182619282851489;14462!GO:0018958;phenol metabolic process;0.0182619282851489;14462!GO:0006584;catecholamine metabolic process;0.0182619282851489;14462!GO:0001817;regulation of cytokine production;0.0182619282851489;14462!GO:0042446;hormone biosynthetic process;0.02085066892257;14462!GO:0042133;neurotransmitter metabolic process;0.02085066892257;14462!GO:0042035;regulation of cytokine biosynthetic process;0.026680634111376;14462!GO:0009309;amine biosynthetic process;0.026680634111376;14462!GO:0042089;cytokine biosynthetic process;0.026680634111376;14462!GO:0042107;cytokine metabolic process;0.026680634111376;14462!GO:0006766;vitamin metabolic process;0.026680634111376;232174!GO:0030326;embryonic limb morphogenesis;0.026680634111376;232174!GO:0035113;embryonic appendage morphogenesis;0.026680634111376;232174!GO:0006576;biogenic amine metabolic process;0.026680634111376;14462!GO:0051327;M phase of meiotic cell cycle;0.026680634111376;232174!GO:0007126;meiosis;0.026680634111376;232174!GO:0051321;meiotic cell cycle;0.026680634111376;232174!GO:0035107;appendage morphogenesis;0.026680634111376;232174!GO:0035108;limb morphogenesis;0.026680634111376;232174!GO:0044271;nitrogen compound biosynthetic process;0.026680634111376;14462!GO:0048869;cellular developmental process;0.026680634111376;14462,232174!GO:0030154;cell differentiation;0.026680634111376;14462,232174!GO:0060173;limb development;0.026680634111376;232174!GO:0048736;appendage development;0.026680634111376;232174!GO:0006575;amino acid derivative metabolic process;0.0284484799788564;14462!GO:0001505;regulation of neurotransmitter levels;0.0284484799788564;14462!GO:0001816;cytokine production;0.0308517453939281;14462!GO:0048856;anatomical structure development;0.0308517453939281;14462,232174!GO:0006725;aromatic compound metabolic process;0.034315035247569;14462!GO:0007275;multicellular organismal development;0.0371332501642451;14462,232174!GO:0006417;regulation of translation;0.0382321834006277;14462!GO:0031326;regulation of cellular biosynthetic process;0.0397928047893852;14462!GO:0046914;transition metal ion binding;0.0400064471977561;14462,232174!GO:0003002;regionalization;0.0405438248376606;232174!GO:0009889;regulation of biosynthetic process;0.0419776548845426;14462!GO:0016563;transcription activator activity;0.0473309004601403;14462!GO:0007268;synaptic transmission;0.0492356523214464;14462!GO:0007283;spermatogenesis;0.0492356523214464;232174!GO:0048232;male gamete generation;0.0492356523214464;232174!GO:0048598;embryonic morphogenesis;0.0499103697559423;232174!
}}

Revision as of 11:24, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr2:9809357..9809371,-p2@Gata3
Mm9::chr2:9809374..9809396,-p4@Gata3
Mm9::chr2:9809402..9809422,-p5@Gata3
Mm9::chr2:9809579..9809627,-p7@Gata3
Mm9::chr2:9811653..9811662,-p8@Gata3
Mm9::chr6:84543910..84543916,-p3@Cyp26b1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001709cell fate determination0.000230308074329499
GO:0042445hormone metabolic process0.0013518082623688
GO:0045165cell fate commitment0.00137684174870896
GO:0032753positive regulation of interleukin-4 production0.00380759327233879
GO:0032673regulation of interleukin-4 production0.00609198234583313
GO:0048485sympathetic nervous system development0.00652694513134735
GO:0042421norepinephrine biosynthetic process0.00652694513134735
GO:0042415norepinephrine metabolic process0.00761435209513292
GO:0048384retinoic acid receptor signaling pathway0.00761435209513292
GO:0032633interleukin-4 production0.00761435209513292
GO:0048483autonomic nervous system development0.00969046256227709
GO:0042573retinoic acid metabolic process0.0101510787109361
GO:0007140male meiosis0.0101510787109361
GO:0009954proximal/distal pattern formation0.0101510787109361
GO:0042423catecholamine biosynthetic process0.0101510787109361
GO:0042136neurotransmitter biosynthetic process0.0123706101935708
GO:0006776vitamin A metabolic process0.0143285785579013
GO:0030522intracellular receptor-mediated signaling pathway0.0152232802682254
GO:0001819positive regulation of cytokine production0.0160236271775587
GO:0006775fat-soluble vitamin metabolic process0.0167437725060497
GO:0042401biogenic amine biosynthetic process0.0173951736223902
GO:0042398amino acid derivative biosynthetic process0.0182619282851489
GO:0018958phenol metabolic process0.0182619282851489
GO:0006584catecholamine metabolic process0.0182619282851489
GO:0001817regulation of cytokine production0.0182619282851489
GO:0042446hormone biosynthetic process0.02085066892257
GO:0042133neurotransmitter metabolic process0.02085066892257
GO:0042035regulation of cytokine biosynthetic process0.026680634111376
GO:0009309amine biosynthetic process0.026680634111376
GO:0042089cytokine biosynthetic process0.026680634111376
GO:0042107cytokine metabolic process0.026680634111376
GO:0006766vitamin metabolic process0.026680634111376
GO:0030326embryonic limb morphogenesis0.026680634111376
GO:0035113embryonic appendage morphogenesis0.026680634111376
GO:0006576biogenic amine metabolic process0.026680634111376
GO:0051327M phase of meiotic cell cycle0.026680634111376
GO:0007126meiosis0.026680634111376
GO:0051321meiotic cell cycle0.026680634111376
GO:0035107appendage morphogenesis0.026680634111376
GO:0035108limb morphogenesis0.026680634111376
GO:0044271nitrogen compound biosynthetic process0.026680634111376
GO:0048869cellular developmental process0.026680634111376
GO:0030154cell differentiation0.026680634111376
GO:0060173limb development0.026680634111376
GO:0048736appendage development0.026680634111376
GO:0006575amino acid derivative metabolic process0.0284484799788564
GO:0001505regulation of neurotransmitter levels0.0284484799788564
GO:0001816cytokine production0.0308517453939281
GO:0048856anatomical structure development0.0308517453939281
GO:0006725aromatic compound metabolic process0.034315035247569
GO:0007275multicellular organismal development0.0371332501642451
GO:0006417regulation of translation0.0382321834006277
GO:0031326regulation of cellular biosynthetic process0.0397928047893852
GO:0046914transition metal ion binding0.0400064471977561
GO:0003002regionalization0.0405438248376606
GO:0009889regulation of biosynthetic process0.0419776548845426
GO:0016563transcription activator activity0.0473309004601403
GO:0007268synaptic transmission0.0492356523214464
GO:0007283spermatogenesis0.0492356523214464
GO:0048232male gamete generation0.0492356523214464
GO:0048598embryonic morphogenesis0.0499103697559423



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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