MCL coexpression mm9:223: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9 | ||
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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0986886653414259,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.247021199245269,0.24749028480297,0,0,0,0,0,0.163875090269313,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.28216905172576,0,0.182264238536694,0.247272523425973,0.0819907263755358,0.172230290669061,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.03677367261284,0.116844694267823,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.164449590503707,0,0.0688732037536692,0,0,0,0.161464196262218,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0242538736058389,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0051179;localization;0.0353914425026023;226359,16170,110784,50884,14799,74020,12323!GO:0045175;basal protein localization;0.0353914425026023;50884!GO:0030950;establishment and/or maintenance of actin cytoskeleton polarity;0.0353914425026023;50884!GO:0032879;regulation of localization;0.0353914425026023;50884!GO:0030952;establishment and/or maintenance of cytoskeleton polarity;0.0353914425026023;50884!GO:0032880;regulation of protein localization;0.0353914425026023;50884!GO:0007509;mesoderm migration;0.0423930149218979;50884!GO:0008078;mesodermal cell migration;0.0423930149218979;50884!GO:0007354;zygotic determination of anterior/posterior axis, embryo;0.0423930149218979;50884!GO:0007616;long-term memory;0.0423930149218979;14799!GO:0006883;cellular sodium ion homeostasis;0.0423930149218979;110784!GO:0055078;sodium ion homeostasis;0.0423930149218979;110784!GO:0031623;receptor internalization;0.0423930149218979;14799!GO:0048570;notochord morphogenesis;0.0423930149218979;50884!GO:0048617;embryonic foregut morphogenesis;0.0423930149218979;50884!GO:0010172;embryonic body morphogenesis;0.0423930149218979;50884!GO:0007440;foregut morphogenesis;0.0423930149218979;50884!GO:0001601;peptide YY receptor activity;0.0423930149218979;18167!GO:0000578;embryonic axis specification;0.0423930149218979;50884!GO:0008595;determination of anterior/posterior axis, embryo;0.0423930149218979;50884!GO:0010171;body morphogenesis;0.0423930149218979;50884!GO:0007351;tripartite regional subdivision;0.0423930149218979;50884!GO:0007350;blastoderm segmentation;0.0423930149218979;50884!GO:0005954;calcium- and calmodulin-dependent protein kinase complex;0.0423930149218979;12323!GO:0048611;embryonic ectodermal gut development;0.0423930149218979;50884!GO:0048613;embryonic ectodermal gut morphogenesis;0.0423930149218979;50884!GO:0050920;regulation of chemotaxis;0.0423930149218979;16170!GO:0050926;regulation of positive chemotaxis;0.0423930149218979;16170!GO:0030004;cellular monovalent inorganic cation homeostasis;0.0423930149218979;110784!GO:0050921;positive regulation of chemotaxis;0.0423930149218979;16170!GO:0030903;notochord development;0.0423930149218979;50884!GO:0050927;positive regulation of positive chemotaxis;0.0423930149218979;16170!GO:0055067;monovalent inorganic cation homeostasis;0.0423930149218979;110784!GO:0050930;induction of positive chemotaxis;0.0423930149218979;16170!GO:0045176;apical protein localization;0.0423930149218979;50884!GO:0042074;cell migration involved in gastrulation;0.0434669182047715;50884!GO:0050821;protein stabilization;0.0434669182047715;50884!GO:0048558;embryonic gut morphogenesis;0.0434669182047715;50884!GO:0050918;positive chemotaxis;0.0434669182047715;16170!GO:0048340;paraxial mesoderm morphogenesis;0.0443380607181023;50884!GO:0031647;regulation of protein stability;0.0443380607181023;50884!GO:0048557;embryonic digestive tract morphogenesis;0.0443380607181023;50884!GO:0008105;asymmetric protein localization;0.0443380607181023;50884!GO:0007439;ectodermal gut development;0.0470607998849367;50884!GO:0048567;ectodermal gut morphogenesis;0.0470607998849367;50884!GO:0048547;gut morphogenesis;0.0495491070566289;50884!GO:0009948;anterior/posterior axis specification;0.0495491070566289;50884! | |gostat_on_MCL_coexpression=GO:0051179;localization;0.0353914425026023;226359,16170,110784,50884,14799,74020,12323!GO:0045175;basal protein localization;0.0353914425026023;50884!GO:0030950;establishment and/or maintenance of actin cytoskeleton polarity;0.0353914425026023;50884!GO:0032879;regulation of localization;0.0353914425026023;50884!GO:0030952;establishment and/or maintenance of cytoskeleton polarity;0.0353914425026023;50884!GO:0032880;regulation of protein localization;0.0353914425026023;50884!GO:0007509;mesoderm migration;0.0423930149218979;50884!GO:0008078;mesodermal cell migration;0.0423930149218979;50884!GO:0007354;zygotic determination of anterior/posterior axis, embryo;0.0423930149218979;50884!GO:0007616;long-term memory;0.0423930149218979;14799!GO:0006883;cellular sodium ion homeostasis;0.0423930149218979;110784!GO:0055078;sodium ion homeostasis;0.0423930149218979;110784!GO:0031623;receptor internalization;0.0423930149218979;14799!GO:0048570;notochord morphogenesis;0.0423930149218979;50884!GO:0048617;embryonic foregut morphogenesis;0.0423930149218979;50884!GO:0010172;embryonic body morphogenesis;0.0423930149218979;50884!GO:0007440;foregut morphogenesis;0.0423930149218979;50884!GO:0001601;peptide YY receptor activity;0.0423930149218979;18167!GO:0000578;embryonic axis specification;0.0423930149218979;50884!GO:0008595;determination of anterior/posterior axis, embryo;0.0423930149218979;50884!GO:0010171;body morphogenesis;0.0423930149218979;50884!GO:0007351;tripartite regional subdivision;0.0423930149218979;50884!GO:0007350;blastoderm segmentation;0.0423930149218979;50884!GO:0005954;calcium- and calmodulin-dependent protein kinase complex;0.0423930149218979;12323!GO:0048611;embryonic ectodermal gut development;0.0423930149218979;50884!GO:0048613;embryonic ectodermal gut morphogenesis;0.0423930149218979;50884!GO:0050920;regulation of chemotaxis;0.0423930149218979;16170!GO:0050926;regulation of positive chemotaxis;0.0423930149218979;16170!GO:0030004;cellular monovalent inorganic cation homeostasis;0.0423930149218979;110784!GO:0050921;positive regulation of chemotaxis;0.0423930149218979;16170!GO:0030903;notochord development;0.0423930149218979;50884!GO:0050927;positive regulation of positive chemotaxis;0.0423930149218979;16170!GO:0055067;monovalent inorganic cation homeostasis;0.0423930149218979;110784!GO:0050930;induction of positive chemotaxis;0.0423930149218979;16170!GO:0045176;apical protein localization;0.0423930149218979;50884!GO:0042074;cell migration involved in gastrulation;0.0434669182047715;50884!GO:0050821;protein stabilization;0.0434669182047715;50884!GO:0048558;embryonic gut morphogenesis;0.0434669182047715;50884!GO:0050918;positive chemotaxis;0.0434669182047715;16170!GO:0048340;paraxial mesoderm morphogenesis;0.0443380607181023;50884!GO:0031647;regulation of protein stability;0.0443380607181023;50884!GO:0048557;embryonic digestive tract morphogenesis;0.0443380607181023;50884!GO:0008105;asymmetric protein localization;0.0443380607181023;50884!GO:0007439;ectodermal gut development;0.0470607998849367;50884!GO:0048567;ectodermal gut morphogenesis;0.0470607998849367;50884!GO:0048547;gut morphogenesis;0.0495491070566289;50884!GO:0009948;anterior/posterior axis specification;0.0495491070566289;50884! | ||
}} | }} |
Revision as of 12:38, 11 October 2012
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0051179 | localization | 0.0353914425026023 |
GO:0045175 | basal protein localization | 0.0353914425026023 |
GO:0030950 | establishment and/or maintenance of actin cytoskeleton polarity | 0.0353914425026023 |
GO:0032879 | regulation of localization | 0.0353914425026023 |
GO:0030952 | establishment and/or maintenance of cytoskeleton polarity | 0.0353914425026023 |
GO:0032880 | regulation of protein localization | 0.0353914425026023 |
GO:0007509 | mesoderm migration | 0.0423930149218979 |
GO:0008078 | mesodermal cell migration | 0.0423930149218979 |
GO:0007354 | zygotic determination of anterior/posterior axis, embryo | 0.0423930149218979 |
GO:0007616 | long-term memory | 0.0423930149218979 |
GO:0006883 | cellular sodium ion homeostasis | 0.0423930149218979 |
GO:0055078 | sodium ion homeostasis | 0.0423930149218979 |
GO:0031623 | receptor internalization | 0.0423930149218979 |
GO:0048570 | notochord morphogenesis | 0.0423930149218979 |
GO:0048617 | embryonic foregut morphogenesis | 0.0423930149218979 |
GO:0010172 | embryonic body morphogenesis | 0.0423930149218979 |
GO:0007440 | foregut morphogenesis | 0.0423930149218979 |
GO:0001601 | peptide YY receptor activity | 0.0423930149218979 |
GO:0000578 | embryonic axis specification | 0.0423930149218979 |
GO:0008595 | determination of anterior/posterior axis, embryo | 0.0423930149218979 |
GO:0010171 | body morphogenesis | 0.0423930149218979 |
GO:0007351 | tripartite regional subdivision | 0.0423930149218979 |
GO:0007350 | blastoderm segmentation | 0.0423930149218979 |
GO:0005954 | calcium- and calmodulin-dependent protein kinase complex | 0.0423930149218979 |
GO:0048611 | embryonic ectodermal gut development | 0.0423930149218979 |
GO:0048613 | embryonic ectodermal gut morphogenesis | 0.0423930149218979 |
GO:0050920 | regulation of chemotaxis | 0.0423930149218979 |
GO:0050926 | regulation of positive chemotaxis | 0.0423930149218979 |
GO:0030004 | cellular monovalent inorganic cation homeostasis | 0.0423930149218979 |
GO:0050921 | positive regulation of chemotaxis | 0.0423930149218979 |
GO:0030903 | notochord development | 0.0423930149218979 |
GO:0050927 | positive regulation of positive chemotaxis | 0.0423930149218979 |
GO:0055067 | monovalent inorganic cation homeostasis | 0.0423930149218979 |
GO:0050930 | induction of positive chemotaxis | 0.0423930149218979 |
GO:0045176 | apical protein localization | 0.0423930149218979 |
GO:0042074 | cell migration involved in gastrulation | 0.0434669182047715 |
GO:0050821 | protein stabilization | 0.0434669182047715 |
GO:0048558 | embryonic gut morphogenesis | 0.0434669182047715 |
GO:0050918 | positive chemotaxis | 0.0434669182047715 |
GO:0048340 | paraxial mesoderm morphogenesis | 0.0443380607181023 |
GO:0031647 | regulation of protein stability | 0.0443380607181023 |
GO:0048557 | embryonic digestive tract morphogenesis | 0.0443380607181023 |
GO:0008105 | asymmetric protein localization | 0.0443380607181023 |
GO:0007439 | ectodermal gut development | 0.0470607998849367 |
GO:0048567 | ectodermal gut morphogenesis | 0.0470607998849367 |
GO:0048547 | gut morphogenesis | 0.0495491070566289 |
GO:0009948 | anterior/posterior axis specification | 0.0495491070566289 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|
Ontology term | p-value | n |
---|
Ontology term | p-value | n |
---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |