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MCL coexpression mm9:1401: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0042392;sphingosine-1-phosphate phosphatase activity;0.00416358505650466;81535!GO:0006668;sphinganine-1-phosphate metabolic process;0.00416358505650466;81535!GO:0006667;sphinganine metabolic process;0.00416358505650466;81535!GO:0006670;sphingosine metabolic process;0.00468390486943811;81535!GO:0015858;nucleoside transport;0.00499602832032906;63959!GO:0005337;nucleoside transmembrane transporter activity;0.00624452212389284;63959!GO:0015932;nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity;0.00624452212389284;63959!GO:0046519;sphingoid metabolic process;0.0195045077024436;81535!GO:0006665;sphingolipid metabolic process;0.0291131581899379;81535!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.0342997033477839;63959!
|gostat_on_MCL_coexpression=GO:0042392;sphingosine-1-phosphate phosphatase activity;0.00416358505650466;81535!GO:0006668;sphinganine-1-phosphate metabolic process;0.00416358505650466;81535!GO:0006667;sphinganine metabolic process;0.00416358505650466;81535!GO:0006670;sphingosine metabolic process;0.00468390486943811;81535!GO:0015858;nucleoside transport;0.00499602832032906;63959!GO:0005337;nucleoside transmembrane transporter activity;0.00624452212389284;63959!GO:0015932;nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity;0.00624452212389284;63959!GO:0046519;sphingoid metabolic process;0.0195045077024436;81535!GO:0006665;sphingolipid metabolic process;0.0291131581899379;81535!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.0342997033477839;63959!
}}
}}

Revision as of 12:56, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr17:45729811..45729845,-p10@Slc29a1
Mm9::chr1:108665556..108665561,-p@chr1:108665556..108665561
-
Mm9::chr5:104865387..104865406,+p2@Spp1
Mm9::chr5:104866664..104866675,+p@chr5:104866664..104866675
+
Mm9::chr5:104869282..104869337,+p@chr5:104869282..104869337
+
Mm9::chr5:104869513..104869546,+p@chr5:104869513..104869546
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042392sphingosine-1-phosphate phosphatase activity0.00416358505650466
GO:0006668sphinganine-1-phosphate metabolic process0.00416358505650466
GO:0006667sphinganine metabolic process0.00416358505650466
GO:0006670sphingosine metabolic process0.00468390486943811
GO:0015858nucleoside transport0.00499602832032906
GO:0005337nucleoside transmembrane transporter activity0.00624452212389284
GO:0015932nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity0.00624452212389284
GO:0046519sphingoid metabolic process0.0195045077024436
GO:0006665sphingolipid metabolic process0.0291131581899379
GO:0015931nucleobase, nucleoside, nucleotide and nucleic acid transport0.0342997033477839



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}