MCL coexpression mm9:1674

Phase1 CAGE Peaks

	Short description
Mm9::chr15:102809727..102809760,-	p@chr15:102809727..102809760 -
Mm9::chr15:77776195..77776210,-	p5@Foxred2
Mm9::chr6:117118584..117118602,+	p1@Cxcl12
Mm9::chr6:117123590..117123595,+	p@chr6:117123590..117123595 +
Mm9::chr6:6831986..6832007,-	p4@Dlx5

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007409	axonogenesis	0.00901934359550232
GO:0048667	neuron morphogenesis during differentiation	0.00901934359550232
GO:0048812	neurite morphogenesis	0.00901934359550232
GO:0000904	cellular morphogenesis during differentiation	0.00901934359550232
GO:0031175	neurite development	0.00901934359550232
GO:0048666	neuron development	0.00901934359550232
GO:0032990	cell part morphogenesis	0.00901934359550232
GO:0048858	cell projection morphogenesis	0.00901934359550232
GO:0030030	cell projection organization and biogenesis	0.00901934359550232
GO:0001667	ameboidal cell migration	0.00901934359550232
GO:0030182	neuron differentiation	0.00901934359550232
GO:0048699	generation of neurons	0.00901934359550232
GO:0008354	germ cell migration	0.00901934359550232
GO:0022008	neurogenesis	0.00901934359550232
GO:0050920	regulation of chemotaxis	0.00901934359550232
GO:0050926	regulation of positive chemotaxis	0.00901934359550232
GO:0050921	positive regulation of chemotaxis	0.00901934359550232
GO:0050927	positive regulation of positive chemotaxis	0.00901934359550232
GO:0050930	induction of positive chemotaxis	0.00901934359550232
GO:0050918	positive chemotaxis	0.009791893617895
GO:0008045	motor axon guidance	0.0104907397135622
GO:0009790	embryonic development	0.0116063327177684
GO:0000902	cell morphogenesis	0.0116063327177684
GO:0032989	cellular structure morphogenesis	0.0116063327177684
GO:0030335	positive regulation of cell migration	0.0125410705591239
GO:0009887	organ morphogenesis	0.0125410705591239
GO:0051272	positive regulation of cell motility	0.0139822882165411
GO:0040017	positive regulation of locomotion	0.0139822882165411
GO:0007399	nervous system development	0.0172446645191495
GO:0001569	patterning of blood vessels	0.017938036737885
GO:0007281	germ cell development	0.0212988683119636
GO:0008009	chemokine activity	0.0281424706336528
GO:0042379	chemokine receptor binding	0.0281424706336528
GO:0009880	embryonic pattern specification	0.0287492167075571
GO:0030334	regulation of cell migration	0.033659692211444
GO:0042472	inner ear morphogenesis	0.033659692211444
GO:0042098	T cell proliferation	0.033659692211444
GO:0001664	G-protein-coupled receptor binding	0.033659692211444
GO:0048754	branching morphogenesis of a tube	0.033659692211444
GO:0051270	regulation of cell motility	0.033659692211444
GO:0042471	ear morphogenesis	0.033659692211444
GO:0001763	morphogenesis of a branching structure	0.033659692211444
GO:0030326	embryonic limb morphogenesis	0.033659692211444
GO:0035113	embryonic appendage morphogenesis	0.033659692211444
GO:0040012	regulation of locomotion	0.033659692211444
GO:0048468	cell development	0.033659692211444
GO:0009653	anatomical structure morphogenesis	0.033659692211444
GO:0048839	inner ear development	0.0343997287833733
GO:0032943	mononuclear cell proliferation	0.0343997287833733
GO:0046651	lymphocyte proliferation	0.0343997287833733
GO:0035107	appendage morphogenesis	0.0343997287833733
GO:0035108	limb morphogenesis	0.0343997287833733
GO:0043583	ear development	0.0343997287833733
GO:0060173	limb development	0.0343997287833733
GO:0048736	appendage development	0.0343997287833733
GO:0007411	axon guidance	0.0343997287833733
GO:0048513	organ development	0.0391832757360438
GO:0042330	taxis	0.0425137244937417
GO:0006935	chemotaxis	0.0425137244937417
GO:0042110	T cell activation	0.0478538696364574

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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