MCL coexpression mm9:2227

Phase1 CAGE Peaks

	Short description
Mm9::chr17:85082363..85082364,+	p9@Abcg8
Mm9::chr9:65142082..65142148,+	p1@Clpx
Mm9::chr9:65142177..65142182,+	p5@Clpx
Mm9::chr9:65142202..65142224,+	p2@Clpx

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016887	ATPase activity	0.00830959984734495
GO:0017111	nucleoside-triphosphatase activity	0.00830959984734495
GO:0016462	pyrophosphatase activity	0.00830959984734495
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.00830959984734495
GO:0016817	hydrolase activity, acting on acid anhydrides	0.00830959984734495
GO:0015914	phospholipid transport	0.0115437245738271
GO:0015918	sterol transport	0.0115437245738271
GO:0042632	cholesterol homeostasis	0.0115437245738271
GO:0055088	lipid homeostasis	0.0115437245738271
GO:0055092	sterol homeostasis	0.0115437245738271
GO:0005524	ATP binding	0.0240962924438208
GO:0032559	adenyl ribonucleotide binding	0.0240962924438208
GO:0030554	adenyl nucleotide binding	0.024510434709358
GO:0032553	ribonucleotide binding	0.0295121511402081
GO:0032555	purine ribonucleotide binding	0.0295121511402081
GO:0017076	purine nucleotide binding	0.0295121511402081
GO:0006869	lipid transport	0.0295121511402081
GO:0000166	nucleotide binding	0.0346050328385511
GO:0016787	hydrolase activity	0.0404228566653644
GO:0006810	transport	0.0474632145525022
GO:0051234	establishment of localization	0.0476778227116422

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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