MCL coexpression mm9:2691

Phase1 CAGE Peaks

	Short description
Mm9::chr11:58768177..58768198,+	p1@Hist3h2a p1@Trim17
Mm9::chr13:21879349..21879363,+	p1@Hist1h2bp
Mm9::chr18:34911457..34911472,+	p2@ENSMUST00000142855 p2@uc008elg.1 p2@uc008elh.1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0006334	nucleosome assembly	0.000388493293769138
GO:0000786	nucleosome	0.000388493293769138
GO:0031497	chromatin assembly	0.000388493293769138
GO:0065004	protein-DNA complex assembly	0.000388493293769138
GO:0006333	chromatin assembly or disassembly	0.000388493293769138
GO:0000785	chromatin	0.000704443506259013
GO:0006325	establishment and/or maintenance of chromatin architecture	0.00107431626855199
GO:0006323	DNA packaging	0.00107431626855199
GO:0044427	chromosomal part	0.00112818178763081
GO:0065003	macromolecular complex assembly	0.00112818178763081
GO:0005694	chromosome	0.00125034159903033
GO:0022607	cellular component assembly	0.00125034159903033
GO:0051276	chromosome organization and biogenesis	0.00125034159903033
GO:0006259	DNA metabolic process	0.00301669719131127
GO:0006996	organelle organization and biogenesis	0.00917587853939728
GO:0043232	intracellular non-membrane-bound organelle	0.0143509833339534
GO:0043228	non-membrane-bound organelle	0.0143509833339534
GO:0043234	protein complex	0.015371719237048
GO:0003677	DNA binding	0.0204462350410961
GO:0032991	macromolecular complex	0.0219648473661512
GO:0044446	intracellular organelle part	0.0265200604225829
GO:0044422	organelle part	0.0265200604225829
GO:0016043	cellular component organization and biogenesis	0.0265200604225829
GO:0003676	nucleic acid binding	0.0350709108219289
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0391014325529621

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}