MCL coexpression mm9:1359

Phase1 CAGE Peaks

	Short description
Mm9::chr14:29323284..29323305,+	p11@Wnt5a
Mm9::chr18:58369710..58369721,-	p1@Fbn2 p1@LOC100047082
Mm9::chr1:12682486..12682500,+	p7@Sulf1
Mm9::chr1:12682514..12682566,+	p2@Sulf1
Mm9::chr1:12682570..12682620,+	p1@Sulf1
Mm9::chr1:12682623..12682635,+	p6@Sulf1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030326	embryonic limb morphogenesis	0.00065475994242359
GO:0035113	embryonic appendage morphogenesis	0.00065475994242359
GO:0035107	appendage morphogenesis	0.00065475994242359
GO:0035108	limb morphogenesis	0.00065475994242359
GO:0048736	appendage development	0.00065475994242359
GO:0060173	limb development	0.00065475994242359
GO:0048598	embryonic morphogenesis	0.00364497440348794
GO:0008449	N-acetylglucosamine-6-sulfatase activity	0.00388934532256473
GO:0004065	arylsulfatase activity	0.00388934532256473
GO:0005578	proteinaceous extracellular matrix	0.004908708499464
GO:0001527	microfibril	0.00530307154345109
GO:0043205	fibril	0.00583305907228608
GO:0005615	extracellular space	0.00685678692274165
GO:0044421	extracellular region part	0.00758169276701373
GO:0009790	embryonic development	0.00801825903984703
GO:0008484	sulfuric ester hydrolase activity	0.00801825903984703
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	0.0137143189205113
GO:0032502	developmental process	0.0142864295074839
GO:0005509	calcium ion binding	0.0198651830124596
GO:0007254	JNK cascade	0.0250313368902236
GO:0031098	stress-activated protein kinase signaling pathway	0.0254983854132012
GO:0006790	sulfur metabolic process	0.0290711091763703
GO:0005201	extracellular matrix structural constituent	0.0290711091763703
GO:0030324	lung development	0.0290711091763703
GO:0009653	anatomical structure morphogenesis	0.0290711091763703
GO:0030323	respiratory tube development	0.0290711091763703
GO:0044420	extracellular matrix part	0.0395641908496913
GO:0000165	MAPKKK cascade	0.0483697919197377
GO:0016055	Wnt receptor signaling pathway	0.0483697919197377

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
multi-cellular organism	5.25e-10	333

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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