MCL coexpression mm9:632

Phase1 CAGE Peaks

	Short description
Mm9::chr10:115614018..115614024,-	p@chr10:115614018..115614024 -
Mm9::chr10:116587456..116587469,-	p@chr10:116587456..116587469 -
Mm9::chr13:16848012..16848016,+	p@chr13:16848012..16848016 +
Mm9::chr13:61036988..61037001,+	p@chr13:61036988..61037001 +
Mm9::chr14:73110565..73110576,-	p@chr14:73110565..73110576 -
Mm9::chr1:195068620..195068627,-	p5@Hsd11b1
Mm9::chr6:3918364..3918381,-	p1@Tfpi2
Mm9::chr6:48522765..48522776,-	p2@Rarres2
Mm9::chr7:129057724..129057744,+	p@chr7:129057724..129057744 +
Mm9::chr7:134306124..134306160,-	p@chr7:134306124..134306160 -
Mm9::chr7:96675672..96675683,-	p6@Prss23

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003845	11-beta-hydroxysteroid dehydrogenase activity	0.0144633758834164

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
embryonic uterus	1.53e-22	4
uterus	1.53e-22	4
female reproductive system	1.55e-21	9
internal female genitalia	4.37e-18	5
female organism	1.48e-17	11
extraembryonic membrane	2.76e-17	3
extraembryonic structure	2.76e-17	3
membranous layer	2.76e-17	3
female reproductive organ	4.24e-17	8
placenta	3.84e-12	2
chorion	3.84e-12	2
allantois	3.84e-12	2
internal genitalia	3.92e-10	9
reproductive structure	3.57e-07	26
reproductive system	3.57e-07	26
uterus or analog	5.73e-07	1
amnion	8.36e-07	1

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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