Novel motif:33

name:	motif33_AGAGCATGAGACGG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0043503	skeletal muscle fiber adaptation	6.913463e-14
GO:0007512	adult heart development	3.680037e-11
GO:0007522	visceral muscle development	1.511833e-10
GO:0051926	negative regulation of calcium ion transport	5.040475e-10
GO:0055009	atrial cardiac muscle tissue morphogenesis	2.330233e-9
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	3.143481e-8
GO:0045750	positive regulation of S phase of mitotic cell cycle	4.013657e-8
GO:0045922	negative regulation of fatty acid metabolic process	1.393481e-7
GO:0051856	adhesion to symbiont	1.452303e-7
GO:0001941	postsynaptic membrane organization	5.122897e-7
GO:0000398	nuclear mRNA splicing, via spliceosome	5.177030e-7
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.223339e-7
GO:0032793	positive regulation of CREB transcription factor activity	6.249947e-7
GO:0046314	phosphocreatine biosynthetic process	6.588383e-7
GO:0050434	positive regulation of viral transcription	7.324090e-7
GO:0014002	astrocyte development	7.679792e-7
GO:0032526	response to retinoic acid	8.044195e-7
GO:0071732	cellular response to nitric oxide	8.199230e-7
GO:0010529	negative regulation of transposition	1.085057e-6
GO:0015816	glycine transport	1.140546e-6
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1.351251e-6
GO:0010991	negative regulation of SMAD protein complex assembly	1.641966e-6
GO:0010765	positive regulation of sodium ion transport	1.643584e-6
GO:0052697	xenobiotic glucuronidation	2.008429e-6
GO:0070980	biphenyl catabolic process	2.008429e-6
GO:0051552	flavone metabolic process	2.008429e-6
GO:0006789	bilirubin conjugation	2.008429e-6
GO:0052696	flavonoid glucuronidation	2.008429e-6
GO:0045618	positive regulation of keratinocyte differentiation	2.013209e-6
GO:0042396	phosphagen biosynthetic process	2.013209e-6
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.433130e-6
GO:0048845	venous blood vessel morphogenesis	3.631581e-6
GO:0000375	RNA splicing, via transesterification reactions	3.696598e-6
GO:0042637	catagen	4.169246e-6
GO:0006032	chitin catabolic process	4.245100e-6
GO:0034447	very-low-density lipoprotein particle clearance	4.374926e-6
GO:0046730	induction of host immune response by virus	4.771657e-6
GO:0035883	enteroendocrine cell differentiation	5.023887e-6
GO:0001974	blood vessel remodeling	5.052381e-6
GO:0010984	regulation of lipoprotein particle clearance	5.335879e-6
GO:0010625	positive regulation of Schwann cell proliferation	5.617632e-6
GO:0034616	response to laminar fluid shear stress	5.869955e-6
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	7.856858e-6
GO:0045606	positive regulation of epidermal cell differentiation	7.856858e-6
GO:0010985	negative regulation of lipoprotein particle clearance	9.049313e-6
GO:0060539	diaphragm development	1.016441e-5
GO:0060743	epithelial cell maturation involved in prostate gland development	1.189632e-5
GO:0060841	venous blood vessel development	1.373266e-5
GO:0032717	negative regulation of interleukin-8 production	1.377513e-5
GO:0071731	response to nitric oxide	1.455290e-5
GO:0060421	positive regulation of heart growth	1.605685e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	1.628800e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	1.655526e-5
GO:0046782	regulation of viral transcription	1.715575e-5
GO:0033239	negative regulation of cellular amine metabolic process	2.006064e-5
GO:0021603	cranial nerve formation	2.408848e-5
GO:0043501	skeletal muscle adaptation	2.441941e-5
GO:0021569	rhombomere 3 development	2.640563e-5
GO:0048075	positive regulation of eye pigmentation	2.649096e-5
GO:0072668	tubulin complex biogenesis	2.709089e-5
GO:0034766	negative regulation of ion transmembrane transport	2.780566e-5
GO:0014888	striated muscle adaptation	2.815948e-5
GO:0002889	regulation of immunoglobulin mediated immune response	2.924880e-5
GO:0009312	oligosaccharide biosynthetic process	2.950854e-5
GO:0071584	negative regulation of zinc ion import	3.373145e-5
GO:0090281	negative regulation of calcium ion import	3.373145e-5
GO:0001909	leukocyte mediated cytotoxicity	3.749186e-5
GO:0035850	epithelial cell differentiation involved in kidney development	3.749420e-5
GO:0046732	active induction of host immune response by virus	3.780059e-5
GO:0010226	response to lithium ion	3.857291e-5
GO:0060124	positive regulation of growth hormone secretion	4.133469e-5
GO:0090141	positive regulation of mitochondrial fission	4.549166e-5
GO:0001886	endothelial cell morphogenesis	4.623186e-5
GO:0006370	mRNA capping	4.629319e-5
GO:0010900	negative regulation of phosphatidylcholine catabolic process	4.706398e-5
GO:0002712	regulation of B cell mediated immunity	4.888756e-5
GO:0045575	basophil activation	4.968750e-5
GO:0001694	histamine biosynthetic process	4.968750e-5
GO:0022617	extracellular matrix disassembly	5.280635e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.415113e-5
GO:0010897	negative regulation of triglyceride catabolic process	5.415113e-5
GO:0009452	RNA capping	5.581548e-5
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	5.708317e-5
GO:0003219	cardiac right ventricle formation	6.288804e-5
GO:0045838	positive regulation of membrane potential	6.594695e-5
GO:0007140	male meiosis	6.864997e-5
GO:0046856	phosphatidylinositol dephosphorylation	7.193190e-5
GO:2000466	negative regulation of glycogen (starch) synthase activity	7.481020e-5
GO:0071474	cellular hyperosmotic response	7.481020e-5
GO:0006352	transcription initiation, DNA-dependent	7.527652e-5
GO:2000001	regulation of DNA damage checkpoint	7.579116e-5
GO:0071874	cellular response to norepinephrine stimulus	7.873742e-5
GO:0071407	cellular response to organic cyclic compound	7.985493e-5
GO:0051013	microtubule severing	8.385198e-5
GO:0006706	steroid catabolic process	8.482659e-5
GO:0048524	positive regulation of viral reproduction	8.703962e-5
GO:0032656	regulation of interleukin-13 production	8.919889e-5
GO:0008617	guanosine metabolic process	8.933279e-5
GO:0060997	dendritic spine morphogenesis	8.934521e-5
GO:0045843	negative regulation of striated muscle tissue development	9.222653e-5
GO:0061302	smooth muscle cell-matrix adhesion	9.496181e-5
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	9.496181e-5
GO:0050792	regulation of viral reproduction	9.510336e-5
GO:0002467	germinal center formation	1.015521e-4
GO:0046839	phospholipid dephosphorylation	1.125756e-4
GO:0032375	negative regulation of cholesterol transport	1.125756e-4
GO:0051890	regulation of cardioblast differentiation	1.126736e-4
GO:0045085	negative regulation of interleukin-2 biosynthetic process	1.149458e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	1.207162e-4
GO:0051005	negative regulation of lipoprotein lipase activity	1.218611e-4
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	1.299488e-4
GO:0050975	sensory perception of touch	1.398047e-4
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	1.518085e-4
GO:0034340	response to type I interferon	1.546870e-4
GO:0006449	regulation of translational termination	1.563500e-4
GO:0072385	minus-end-directed organelle transport along microtubule	1.584310e-4
GO:0033326	cerebrospinal fluid secretion	1.615065e-4
GO:0010923	negative regulation of phosphatase activity	1.657577e-4
GO:0010936	negative regulation of macrophage cytokine production	1.700222e-4
GO:0034436	glycoprotein transport	1.700926e-4
GO:0009720	detection of hormone stimulus	1.700926e-4
GO:0070309	lens fiber cell morphogenesis	1.717394e-4
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	1.798289e-4
GO:0060337	type I interferon-mediated signaling pathway	1.800696e-4
GO:0021546	rhombomere development	1.856946e-4
GO:0043380	regulation of memory T cell differentiation	1.904177e-4
GO:0060020	Bergmann glial cell differentiation	1.936764e-4
GO:2000465	regulation of glycogen (starch) synthase activity	1.994443e-4
GO:0045940	positive regulation of steroid metabolic process	2.137029e-4
GO:0007141	male meiosis I	2.165483e-4
GO:0000387	spliceosomal snRNP assembly	2.204320e-4
GO:2001076	positive regulation of metanephric ureteric bud development	2.258096e-4
GO:0007356	thorax and anterior abdomen determination	2.258096e-4
GO:0070508	cholesterol import	2.271993e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2.412216e-4
GO:0043243	positive regulation of protein complex disassembly	2.448387e-4
GO:0003329	pancreatic PP cell fate commitment	2.495465e-4
GO:0003326	pancreatic A cell fate commitment	2.495465e-4
GO:0014733	regulation of skeletal muscle adaptation	2.501384e-4
GO:0035066	positive regulation of histone acetylation	2.525409e-4
GO:0060123	regulation of growth hormone secretion	2.680460e-4
GO:0072321	chaperone-mediated protein transport	2.783765e-4
GO:0060996	dendritic spine development	2.831017e-4
GO:0048708	astrocyte differentiation	3.043090e-4
GO:0015804	neutral amino acid transport	3.119927e-4
GO:0007007	inner mitochondrial membrane organization	3.194676e-4
GO:0019062	virion attachment to host cell surface receptor	3.325721e-4
GO:0045039	protein import into mitochondrial inner membrane	3.339449e-4
GO:0048486	parasympathetic nervous system development	3.340338e-4
GO:0006379	mRNA cleavage	3.392059e-4
GO:0014057	positive regulation of acetylcholine secretion	3.426953e-4
GO:0045819	positive regulation of glycogen catabolic process	3.594945e-4
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	3.737078e-4
GO:0060923	cardiac muscle cell fate commitment	3.737078e-4
GO:0010893	positive regulation of steroid biosynthetic process	3.787675e-4
GO:0007109	cytokinesis, completion of separation	3.790789e-4
GO:0032425	positive regulation of mismatch repair	3.842166e-4
GO:0007585	respiratory gaseous exchange	3.846024e-4
GO:0046684	response to pyrethroid	3.896805e-4
GO:0045191	regulation of isotype switching	3.997988e-4
GO:0001885	endothelial cell development	4.669329e-4
GO:0060712	spongiotrophoblast layer development	4.764043e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.769266e-4
GO:0035871	protein K11-linked deubiquitination	4.923289e-4
GO:0002719	negative regulation of cytokine production involved in immune response	4.953239e-4
GO:0046814	virion attachment, binding of host cell surface coreceptor	4.973352e-4
GO:0032472	Golgi calcium ion transport	4.973352e-4
GO:0030026	cellular manganese ion homeostasis	4.973352e-4
GO:0032468	Golgi calcium ion homeostasis	4.973352e-4
GO:0060696	regulation of phospholipid catabolic process	5.094367e-4
GO:0007354	zygotic determination of anterior/posterior axis, embryo	5.190649e-4
GO:0097120	receptor localization to synapse	5.267963e-4
GO:0032736	positive regulation of interleukin-13 production	5.267963e-4
GO:0072578	neurotransmitter-gated ion channel clustering	5.267963e-4
GO:0070831	basement membrane assembly	5.295850e-4
GO:0018205	peptidyl-lysine modification	5.374838e-4
GO:0048073	regulation of eye pigmentation	5.460843e-4
GO:0008292	acetylcholine biosynthetic process	5.460843e-4
GO:0031558	induction of apoptosis in response to chemical stimulus	5.682803e-4
GO:0035461	vitamin transmembrane transport	5.754579e-4
GO:0000414	regulation of histone H3-K36 methylation	5.810736e-4
GO:0005993	trehalose catabolic process	5.884622e-4
GO:0070179	D-serine biosynthetic process	5.888737e-4
GO:0051793	medium-chain fatty acid catabolic process	5.888737e-4
GO:0033189	response to vitamin A	6.025040e-4
GO:0003264	regulation of cardioblast proliferation	6.092063e-4
GO:0018879	biphenyl metabolic process	6.180223e-4
GO:0055099	response to high density lipoprotein particle stimulus	6.214573e-4
GO:0034405	response to fluid shear stress	6.258543e-4
GO:0061005	cell differentiation involved in kidney development	6.488494e-4
GO:0072393	microtubule anchoring at microtubule organizing center	6.586158e-4
GO:0002070	epithelial cell maturation	6.825323e-4
GO:0035305	negative regulation of dephosphorylation	6.852095e-4
GO:0007271	synaptic transmission, cholinergic	7.132929e-4
GO:0071681	cellular response to indole-3-methanol	7.157375e-4
GO:0009311	oligosaccharide metabolic process	7.211044e-4
GO:0000244	assembly of spliceosomal tri-snRNP	7.350286e-4
GO:0042723	thiamine-containing compound metabolic process	7.382432e-4
GO:0006353	transcription termination, DNA-dependent	7.449819e-4
GO:0050689	negative regulation of defense response to virus by host	7.547508e-4
GO:0048143	astrocyte activation	7.594845e-4
GO:0002028	regulation of sodium ion transport	7.617324e-4
GO:0045589	regulation of regulatory T cell differentiation	7.639142e-4
GO:0033578	protein glycosylation in Golgi	7.639142e-4
GO:0043491	protein kinase B signaling cascade	7.703580e-4
GO:0045830	positive regulation of isotype switching	7.867707e-4
GO:0008380	RNA splicing	7.897267e-4
GO:0045446	endothelial cell differentiation	7.939513e-4
GO:0006285	base-excision repair, AP site formation	7.988586e-4
GO:0072166	posterior mesonephric tubule development	8.007828e-4
GO:0003230	cardiac atrium development	8.479464e-4
GO:0048642	negative regulation of skeletal muscle tissue development	8.629655e-4
GO:0048771	tissue remodeling	8.673304e-4
GO:0051702	interaction with symbiont	8.689684e-4
GO:0006540	glutamate decarboxylation to succinate	8.699504e-4
GO:0006417	regulation of translation	8.727245e-4
GO:0051177	meiotic sister chromatid cohesion	8.752427e-4
GO:0017004	cytochrome complex assembly	8.891945e-4
GO:0000416	positive regulation of histone H3-K36 methylation	8.891945e-4
GO:0010034	response to acetate	8.926745e-4
GO:0045590	negative regulation of regulatory T cell differentiation	8.926745e-4
GO:0061307	cardiac neural crest cell differentiation involved in heart development	8.988920e-4
GO:0072112	glomerular visceral epithelial cell differentiation	9.203905e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	9.207107e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.472343e-4
GO:0002071	glandular epithelial cell maturation	9.633688e-4
GO:0006701	progesterone biosynthetic process	9.836188e-4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.018842e-3
GO:0001575	globoside metabolic process	1.024318e-3
GO:0035752	lysosomal lumen pH elevation	1.024318e-3
GO:0000046	autophagic vacuole fusion	1.024318e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.024981e-3
GO:0003158	endothelium development	1.035194e-3
GO:0010872	regulation of cholesterol esterification	1.040615e-3
GO:0072194	kidney smooth muscle tissue development	1.051841e-3
GO:0034959	endothelin maturation	1.051841e-3
GO:0010814	substance P catabolic process	1.051841e-3
GO:0010816	calcitonin catabolic process	1.051841e-3
GO:0002064	epithelial cell development	1.082535e-3
GO:0006772	thiamine metabolic process	1.089680e-3
GO:0046070	dGTP metabolic process	1.111927e-3
GO:0045726	positive regulation of integrin biosynthetic process	1.111927e-3
GO:0000920	cytokinetic cell separation	1.111927e-3
GO:0033344	cholesterol efflux	1.117159e-3
GO:0007266	Rho protein signal transduction	1.128356e-3
GO:0051764	actin crosslink formation	1.135775e-3
GO:0042117	monocyte activation	1.153180e-3
GO:0010452	histone H3-K36 methylation	1.154344e-3
GO:0032835	glomerulus development	1.209111e-3
GO:0006884	cell volume homeostasis	1.212495e-3
GO:0022007	convergent extension involved in neural plate elongation	1.258740e-3
GO:0051580	regulation of neurotransmitter uptake	1.259922e-3
GO:0071316	cellular response to nicotine	1.289835e-3
GO:0000089	mitotic metaphase	1.293766e-3
GO:0045076	regulation of interleukin-2 biosynthetic process	1.322011e-3
GO:0045008	depyrimidination	1.325444e-3
GO:0021612	facial nerve structural organization	1.331818e-3
GO:0015734	taurine transport	1.334109e-3
GO:0061032	visceral serous pericardium development	1.334109e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.334109e-3
GO:0048210	Golgi vesicle fusion to target membrane	1.334109e-3
GO:0010693	negative regulation of alkaline phosphatase activity	1.345847e-3
GO:0006283	transcription-coupled nucleotide-excision repair	1.356012e-3
GO:0019064	viral envelope fusion with host membrane	1.356598e-3
GO:0007179	transforming growth factor beta receptor signaling pathway	1.359748e-3
GO:0043149	stress fiber assembly	1.363812e-3
GO:0048477	oogenesis	1.403664e-3
GO:0070625	zymogen granule exocytosis	1.433254e-3
GO:0090149	membrane fission involved in mitochondrial fission	1.433254e-3
GO:0014895	smooth muscle hypertrophy	1.433254e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.433254e-3
GO:0002082	regulation of oxidative phosphorylation	1.433254e-3
GO:0003374	dynamin polymerization involved in mitochondrial fission	1.433254e-3
GO:0006026	aminoglycan catabolic process	1.434974e-3
GO:0090140	regulation of mitochondrial fission	1.439272e-3
GO:0030828	positive regulation of cGMP biosynthetic process	1.440633e-3
GO:0042942	D-serine transport	1.443785e-3
GO:0007023	post-chaperonin tubulin folding pathway	1.468640e-3
GO:0032836	glomerular basement membrane development	1.478207e-3
GO:0006828	manganese ion transport	1.518454e-3
GO:0070383	DNA cytosine deamination	1.555684e-3
GO:0021570	rhombomere 4 development	1.555684e-3
GO:0032423	regulation of mismatch repair	1.608287e-3
GO:0002513	tolerance induction to self antigen	1.620943e-3
GO:0001826	inner cell mass cell differentiation	1.672100e-3
GO:0060252	positive regulation of glial cell proliferation	1.695704e-3
GO:0043586	tongue development	1.723811e-3
GO:0043382	positive regulation of memory T cell differentiation	1.731457e-3
GO:0016188	synaptic vesicle maturation	1.743047e-3
GO:0071585	detoxification of cadmium ion	1.747531e-3
GO:0070946	neutrophil mediated killing of gram-positive bacterium	1.747531e-3
GO:0002703	regulation of leukocyte mediated immunity	1.780671e-3
GO:0051569	regulation of histone H3-K4 methylation	1.795840e-3
GO:0072075	metanephric mesenchyme development	1.807399e-3
GO:0003382	epithelial cell morphogenesis	1.827302e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.845584e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.888805e-3
GO:0070483	detection of hypoxia	1.918881e-3
GO:0090324	negative regulation of oxidative phosphorylation	1.920258e-3
GO:0010255	glucose mediated signaling pathway	1.920258e-3
GO:0070873	regulation of glycogen metabolic process	1.932957e-3
GO:0030302	deoxynucleotide transport	1.939584e-3
GO:0009804	coumarin metabolic process	1.939584e-3
GO:0034384	high-density lipoprotein particle clearance	1.963465e-3
GO:0016559	peroxisome fission	1.977001e-3
GO:0071280	cellular response to copper ion	1.977001e-3
GO:0070294	renal sodium ion absorption	1.983627e-3
GO:0070875	positive regulation of glycogen metabolic process	1.989558e-3
GO:0060126	somatotropin secreting cell differentiation	2.000814e-3
GO:0002026	regulation of the force of heart contraction	2.010251e-3
GO:0006354	transcription elongation, DNA-dependent	2.028665e-3
GO:0006244	pyrimidine nucleotide catabolic process	2.031724e-3
GO:0072195	kidney smooth muscle cell differentiation	2.040095e-3
GO:0072105	ureteric peristalsis	2.040095e-3
GO:0051668	localization within membrane	2.048298e-3
GO:2000543	positive regulation of gastrulation	2.057981e-3
GO:0046622	positive regulation of organ growth	2.099171e-3
GO:0070734	histone H3-K27 methylation	2.117562e-3
GO:0006707	cholesterol catabolic process	2.144382e-3
GO:0021783	preganglionic parasympathetic nervous system development	2.145072e-3
GO:0050720	interleukin-1 beta biosynthetic process	2.156936e-3
GO:0021599	abducens nerve formation	2.156936e-3
GO:0061090	positive regulation of sequestering of zinc ion	2.156936e-3
GO:0016191	synaptic vesicle uncoating	2.156936e-3
GO:0007634	optokinetic behavior	2.156936e-3
GO:0043538	regulation of actin phosphorylation	2.201802e-3
GO:0051089	constitutive protein ectodomain proteolysis	2.201802e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	2.201802e-3
GO:0007285	primary spermatocyte growth	2.201802e-3
GO:0055005	ventricular cardiac myofibril development	2.210650e-3
GO:0051891	positive regulation of cardioblast differentiation	2.238427e-3
GO:0021571	rhombomere 5 development	2.273560e-3
GO:0033119	negative regulation of RNA splicing	2.279252e-3
GO:0055026	negative regulation of cardiac muscle tissue development	2.299448e-3
GO:0042267	natural killer cell mediated cytotoxicity	2.321380e-3
GO:0016078	tRNA catabolic process	2.345041e-3
GO:0007198	inhibition of adenylate cyclase activity by serotonin receptor signaling pathway	2.345041e-3
GO:0001682	tRNA 5'-leader removal	2.345041e-3
GO:0090128	regulation of synapse maturation	2.370170e-3
GO:0043462	regulation of ATPase activity	2.370618e-3
GO:0048148	behavioral response to cocaine	2.435274e-3
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	2.481348e-3
GO:0006538	glutamate catabolic process	2.543156e-3
GO:0007352	zygotic specification of dorsal/ventral axis	2.543156e-3
GO:0002238	response to molecule of fungal origin	2.637500e-3
GO:0070943	neutrophil mediated killing of symbiont cell	2.665074e-3
GO:0042760	very long-chain fatty acid catabolic process	2.665074e-3
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	2.667085e-3
GO:0042167	heme catabolic process	2.741601e-3
GO:0051927	negative regulation of calcium ion transport via voltage-gated calcium channel activity	2.838465e-3
GO:0018023	peptidyl-lysine trimethylation	2.840730e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	2.852015e-3
GO:0060973	cell migration involved in heart development	2.857453e-3
GO:0045351	type I interferon biosynthetic process	2.857453e-3
GO:0072189	ureter development	2.887514e-3
GO:0010692	regulation of alkaline phosphatase activity	2.887514e-3
GO:0043932	ossification involved in bone remodeling	2.972132e-3
GO:0006054	N-acetylneuraminate metabolic process	2.976169e-3
GO:0001807	regulation of type IV hypersensitivity	2.976169e-3
GO:0071108	protein K48-linked deubiquitination	2.981945e-3
GO:0032202	telomere assembly	3.013168e-3
GO:0090129	positive regulation of synapse maturation	3.013168e-3
GO:0010536	positive regulation of activation of Janus kinase activity	3.013168e-3
GO:0003266	regulation of secondary heart field cardioblast proliferation	3.013168e-3
GO:0003417	growth plate cartilage development	3.029047e-3
GO:0048320	axial mesoderm formation	3.063748e-3
GO:0046683	response to organophosphorus	3.086953e-3
GO:0051148	negative regulation of muscle cell differentiation	3.114657e-3
GO:0060837	blood vessel endothelial cell differentiation	3.124417e-3
GO:0034776	response to histamine	3.124417e-3
GO:0030902	hindbrain development	3.138428e-3
GO:0071236	cellular response to antibiotic	3.188091e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	3.203095e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	3.226986e-3
GO:0030852	regulation of granulocyte differentiation	3.242352e-3
GO:0042398	cellular modified amino acid biosynthetic process	3.243106e-3
GO:0018022	peptidyl-lysine methylation	3.316305e-3
GO:0060177	regulation of angiotensin metabolic process	3.316305e-3
GO:0045066	regulatory T cell differentiation	3.319351e-3
GO:0006473	protein acetylation	3.361874e-3
GO:0070857	regulation of bile acid biosynthetic process	3.396262e-3
GO:2000109	regulation of macrophage apoptosis	3.398814e-3
GO:0003209	cardiac atrium morphogenesis	3.403045e-3
GO:0032606	type I interferon production	3.416951e-3
GO:0018963	phthalate metabolic process	3.416951e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.429337e-3
GO:0034330	cell junction organization	3.433856e-3
GO:0017148	negative regulation of translation	3.479504e-3
GO:0035303	regulation of dephosphorylation	3.485039e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	3.594404e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	3.594404e-3
GO:0045006	DNA deamination	3.594404e-3
GO:0050765	negative regulation of phagocytosis	3.642059e-3
GO:0006047	UDP-N-acetylglucosamine metabolic process	3.834965e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	3.834965e-3
GO:0030433	ER-associated protein catabolic process	3.911780e-3
GO:0010621	negative regulation of transcription by transcription factor localization	3.979547e-3
GO:0070141	response to UV-A	3.982000e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	4.006755e-3
GO:0009817	defense response to fungus, incompatible interaction	4.006755e-3
GO:0003014	renal system process	4.026496e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	4.029683e-3
GO:0032411	positive regulation of transporter activity	4.051627e-3
GO:0035499	carnosine biosynthetic process	4.079413e-3
GO:0016242	negative regulation of macroautophagy	4.079413e-3
GO:0003181	atrioventricular valve morphogenesis	4.096366e-3
GO:0016579	protein deubiquitination	4.099455e-3
GO:0035815	positive regulation of renal sodium excretion	4.108597e-3
GO:0000578	embryonic axis specification	4.123439e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	4.150009e-3
GO:0051131	chaperone-mediated protein complex assembly	4.156241e-3
GO:0051571	positive regulation of histone H3-K4 methylation	4.207632e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	4.259077e-3
GO:0045175	basal protein localization	4.259950e-3
GO:0051665	membrane raft localization	4.352178e-3
GO:0030826	regulation of cGMP biosynthetic process	4.403529e-3
GO:0045901	positive regulation of translational elongation	4.411030e-3
GO:0045905	positive regulation of translational termination	4.411030e-3
GO:0006452	translational frameshifting	4.411030e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	4.512348e-3
GO:0014056	regulation of acetylcholine secretion	4.515986e-3
GO:0009298	GDP-mannose biosynthetic process	4.568692e-3
GO:0015788	UDP-N-acetylglucosamine transport	4.583766e-3
GO:0006474	N-terminal protein amino acid acetylation	4.592420e-3
GO:0009225	nucleotide-sugar metabolic process	4.655796e-3
GO:0048635	negative regulation of muscle organ development	4.665526e-3
GO:0045109	intermediate filament organization	4.746300e-3
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	4.782948e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	4.804168e-3
GO:0035284	brain segmentation	4.804168e-3
GO:0000090	mitotic anaphase	4.840026e-3
GO:0002002	regulation of angiotensin levels in blood	4.887063e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	4.945820e-3
GO:0060426	lung vasculature development	4.981798e-3
GO:0070345	negative regulation of fat cell proliferation	5.011701e-3
GO:0050890	cognition	5.019527e-3
GO:0060319	primitive erythrocyte differentiation	5.058599e-3
GO:0002575	basophil chemotaxis	5.058599e-3
GO:0016137	glycoside metabolic process	5.137797e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	5.137797e-3
GO:2000209	regulation of anoikis	5.223571e-3
GO:0007379	segment specification	5.278669e-3
GO:0045911	positive regulation of DNA recombination	5.339097e-3
GO:0032792	negative regulation of CREB transcription factor activity	5.343431e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	5.394395e-3
GO:0032506	cytokinetic process	5.420482e-3
GO:0043500	muscle adaptation	5.435416e-3
GO:0016264	gap junction assembly	5.439509e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	5.472934e-3
GO:0021610	facial nerve morphogenesis	5.550879e-3
GO:0003416	endochondral bone growth	5.555208e-3
GO:0007021	tubulin complex assembly	5.604347e-3
GO:0050764	regulation of phagocytosis	5.758947e-3
GO:0042472	inner ear morphogenesis	5.830366e-3
GO:0090103	cochlea morphogenesis	5.888282e-3
GO:0033146	regulation of estrogen receptor signaling pathway	5.925525e-3
GO:2001014	regulation of skeletal muscle cell differentiation	5.931059e-3
GO:0071318	cellular response to ATP	6.117569e-3
GO:0009404	toxin metabolic process	6.216079e-3
GO:0019852	L-ascorbic acid metabolic process	6.236581e-3
GO:0019747	regulation of isoprenoid metabolic process	6.253382e-3
GO:0002457	T cell antigen processing and presentation	6.253382e-3
GO:0010477	response to sulfur dioxide	6.253382e-3
GO:0051902	negative regulation of mitochondrial depolarization	6.272365e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	6.335080e-3
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	6.347473e-3
GO:0032957	inositol trisphosphate metabolic process	6.376593e-3
GO:0033003	regulation of mast cell activation	6.392088e-3
GO:0070858	negative regulation of bile acid biosynthetic process	6.402894e-3
GO:0002250	adaptive immune response	6.508647e-3
GO:0001773	myeloid dendritic cell activation	6.514091e-3
GO:0060561	apoptosis involved in morphogenesis	6.544956e-3
GO:0006700	C21-steroid hormone biosynthetic process	6.558275e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	6.566479e-3
GO:0048488	synaptic vesicle endocytosis	6.567598e-3
GO:0042104	positive regulation of activated T cell proliferation	6.612582e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	6.735458e-3
GO:0071105	response to interleukin-11	6.735458e-3
GO:0006713	glucocorticoid catabolic process	6.735458e-3
GO:0090370	negative regulation of cholesterol efflux	6.829920e-3
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	6.829920e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	6.829920e-3
GO:0032119	sequestering of zinc ion	6.829920e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	6.856553e-3
GO:0043049	otic placode formation	6.873120e-3
GO:0030432	peristalsis	6.873120e-3
GO:0043543	protein acylation	6.877800e-3
GO:0045113	regulation of integrin biosynthetic process	6.906297e-3
GO:0003310	pancreatic A cell differentiation	7.005715e-3
GO:0006546	glycine catabolic process	7.090473e-3
GO:0035712	T-helper 2 cell activation	7.091560e-3
GO:2000525	positive regulation of T cell costimulation	7.091560e-3
GO:0071954	chemokine (C-C motif) ligand 11 production	7.091560e-3
GO:0035709	memory T cell activation	7.091560e-3
GO:0002215	defense response to nematode	7.091560e-3
GO:0015878	biotin transport	7.091560e-3
GO:0015887	pantothenate transmembrane transport	7.091560e-3
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	7.091560e-3
GO:0060977	coronary vasculature morphogenesis	7.113678e-3
GO:0042178	xenobiotic catabolic process	7.138425e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0070646	protein modification by small protein removal	1.390297e-12
GO:0016579	protein deubiquitination	1.211142e-11
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.637368e-9
GO:0003229	ventricular cardiac muscle tissue development	6.772919e-9
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.245005e-8
GO:0007522	visceral muscle development	1.270237e-7
GO:0003230	cardiac atrium development	2.135292e-7
GO:0060696	regulation of phospholipid catabolic process	3.472141e-7
GO:0055010	ventricular cardiac muscle tissue morphogenesis	5.469414e-7
GO:0048340	paraxial mesoderm morphogenesis	6.143414e-7
GO:0030509	BMP signaling pathway	7.486412e-7
GO:0034447	very-low-density lipoprotein particle clearance	1.248226e-6
GO:0051055	negative regulation of lipid biosynthetic process	1.330562e-6
GO:0042254	ribosome biogenesis	1.874243e-6
GO:0015780	nucleotide-sugar transport	1.953789e-6
GO:0033239	negative regulation of cellular amine metabolic process	1.964725e-6
GO:0016072	rRNA metabolic process	3.327351e-6
GO:0033143	regulation of steroid hormone receptor signaling pathway	3.385052e-6
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	5.207825e-6
GO:0009303	rRNA transcription	5.501647e-6
GO:0048532	anatomical structure arrangement	5.895322e-6
GO:0060012	synaptic transmission, glycinergic	6.214341e-6
GO:0031558	induction of apoptosis in response to chemical stimulus	6.419702e-6
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	6.705467e-6
GO:0022417	protein maturation by protein folding	6.705467e-6
GO:0006941	striated muscle contraction	1.089093e-5
GO:0045833	negative regulation of lipid metabolic process	1.449332e-5
GO:0030049	muscle filament sliding	1.481797e-5
GO:0006364	rRNA processing	1.492977e-5
GO:0003209	cardiac atrium morphogenesis	1.521205e-5
GO:0048339	paraxial mesoderm development	1.559548e-5
GO:2000657	negative regulation of apolipoprotein binding	1.708131e-5
GO:0006409	tRNA export from nucleus	1.708131e-5
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	1.708131e-5
GO:0042476	odontogenesis	2.097871e-5
GO:2000378	negative regulation of reactive oxygen species metabolic process	2.173698e-5
GO:0032288	myelin assembly	2.326565e-5
GO:0018924	mandelate metabolic process	2.357456e-5
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.421735e-5
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	2.694377e-5
GO:0035621	ER to Golgi ceramide transport	2.694377e-5
GO:0032218	riboflavin transport	2.694377e-5
GO:0043462	regulation of ATPase activity	2.989305e-5
GO:2000736	regulation of stem cell differentiation	3.093897e-5
GO:0009081	branched chain family amino acid metabolic process	3.162727e-5
GO:0070647	protein modification by small protein conjugation or removal	4.317887e-5
GO:0043558	regulation of translational initiation in response to stress	4.353940e-5
GO:0048739	cardiac muscle fiber development	4.410883e-5
GO:0045806	negative regulation of endocytosis	4.561636e-5
GO:0050665	hydrogen peroxide biosynthetic process	6.055915e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	6.083025e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	6.083025e-5
GO:0043555	regulation of translation in response to stress	6.322944e-5
GO:0032328	alanine transport	6.373952e-5
GO:0048352	paraxial mesoderm structural organization	6.697511e-5
GO:0021998	neural plate mediolateral regionalization	6.697511e-5
GO:0008334	histone mRNA metabolic process	7.203484e-5
GO:0060033	anatomical structure regression	7.761476e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	7.905598e-5
GO:0015669	gas transport	7.927451e-5
GO:0045872	positive regulation of rhodopsin gene expression	8.196572e-5
GO:0043252	sodium-independent organic anion transport	8.196572e-5
GO:0043243	positive regulation of protein complex disassembly	8.566928e-5
GO:0070079	histone H4-R3 demethylation	8.765870e-5
GO:0070078	histone H3-R2 demethylation	8.765870e-5
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	8.765870e-5
GO:0023035	CD40 signaling pathway	8.765870e-5
GO:0021603	cranial nerve formation	9.162379e-5
GO:0021943	formation of radial glial scaffolds	9.278874e-5
GO:0003093	regulation of glomerular filtration	9.973252e-5
GO:0006668	sphinganine-1-phosphate metabolic process	1.015711e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.031926e-4
GO:0009083	branched chain family amino acid catabolic process	1.044251e-4
GO:0071104	response to interleukin-9	1.064045e-4
GO:0044062	regulation of excretion	1.087756e-4
GO:0055008	cardiac muscle tissue morphogenesis	1.114664e-4
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.117336e-4
GO:0033129	positive regulation of histone phosphorylation	1.124194e-4
GO:0051005	negative regulation of lipoprotein lipase activity	1.184225e-4
GO:0018205	peptidyl-lysine modification	1.328354e-4
GO:0097039	protein linear polyubiquitination	1.374518e-4
GO:0030913	paranodal junction assembly	1.378741e-4
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	1.442543e-4
GO:0051004	regulation of lipoprotein lipase activity	1.491195e-4
GO:0000460	maturation of 5.8S rRNA	1.536289e-4
GO:0008366	axon ensheathment	1.687363e-4
GO:0001964	startle response	1.745044e-4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	1.763803e-4
GO:0045793	positive regulation of cell size	1.884725e-4
GO:0046784	intronless viral mRNA export from host nucleus	1.917896e-4
GO:0060541	respiratory system development	1.987873e-4
GO:0006401	RNA catabolic process	2.050860e-4
GO:0003218	cardiac left ventricle formation	2.051423e-4
GO:0006360	transcription from RNA polymerase I promoter	2.054493e-4
GO:0042508	tyrosine phosphorylation of Stat1 protein	2.139949e-4
GO:0032287	peripheral nervous system myelin maintenance	2.173047e-4
GO:2000739	regulation of mesenchymal stem cell differentiation	2.195270e-4
GO:0022613	ribonucleoprotein complex biogenesis	2.214438e-4
GO:0045040	protein import into mitochondrial outer membrane	2.276733e-4
GO:0071294	cellular response to zinc ion	2.282027e-4
GO:0071397	cellular response to cholesterol	2.291000e-4
GO:0071529	cementum mineralization	2.299089e-4
GO:0006449	regulation of translational termination	2.299089e-4
GO:0009889	regulation of biosynthetic process	2.317317e-4
GO:0060039	pericardium development	2.342210e-4
GO:0031326	regulation of cellular biosynthetic process	2.353020e-4
GO:0001880	Mullerian duct regression	2.353271e-4
GO:0010724	regulation of definitive erythrocyte differentiation	2.353271e-4
GO:0070172	positive regulation of tooth mineralization	2.391453e-4
GO:0032774	RNA biosynthetic process	2.467155e-4
GO:0072086	specification of loop of Henle identity	2.495269e-4
GO:0031323	regulation of cellular metabolic process	2.568478e-4
GO:0006351	transcription, DNA-dependent	2.605916e-4
GO:0034382	chylomicron remnant clearance	2.724175e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	2.748139e-4
GO:0016568	chromatin modification	3.004806e-4
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	3.051374e-4
GO:0071711	basement membrane organization	3.148844e-4
GO:0009082	branched chain family amino acid biosynthetic process	3.148844e-4
GO:0071843	cellular component biogenesis at cellular level	3.285600e-4
GO:0007260	tyrosine phosphorylation of STAT protein	3.448058e-4
GO:0021570	rhombomere 4 development	3.535585e-4
GO:0001977	renal system process involved in regulation of blood volume	3.575509e-4
GO:0006398	histone mRNA 3'-end processing	3.593137e-4
GO:0035441	cell migration involved in vasculogenesis	3.593137e-4
GO:0051171	regulation of nitrogen compound metabolic process	3.595939e-4
GO:0031117	positive regulation of microtubule depolymerization	3.654486e-4
GO:2000426	negative regulation of apoptotic cell clearance	3.725987e-4
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.725987e-4
GO:0048291	isotype switching to IgG isotypes	3.933047e-4
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	3.933047e-4
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	3.933047e-4
GO:0002368	B cell cytokine production	3.933047e-4
GO:0002731	negative regulation of dendritic cell cytokine production	3.933047e-4
GO:0045221	negative regulation of FasL biosynthetic process	3.933047e-4
GO:0006308	DNA catabolic process	4.034817e-4
GO:0045922	negative regulation of fatty acid metabolic process	4.075286e-4
GO:0032900	negative regulation of neurotrophin production	4.114441e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	4.114441e-4
GO:0032244	positive regulation of nucleoside transport	4.114441e-4
GO:0014057	positive regulation of acetylcholine secretion	4.114441e-4
GO:0010045	response to nickel ion	4.114441e-4
GO:0035815	positive regulation of renal sodium excretion	4.132584e-4
GO:0060415	muscle tissue morphogenesis	4.196443e-4
GO:0060192	negative regulation of lipase activity	4.327352e-4
GO:0016070	RNA metabolic process	4.374038e-4
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	4.518121e-4
GO:0010501	RNA secondary structure unwinding	4.518121e-4
GO:0030262	apoptotic nuclear change	4.568192e-4
GO:0060760	positive regulation of response to cytokine stimulus	4.594364e-4
GO:0060026	convergent extension	4.695767e-4
GO:0043622	cortical microtubule organization	4.712722e-4
GO:0030103	vasopressin secretion	4.712722e-4
GO:0007231	osmosensory signaling pathway	4.712722e-4
GO:0070936	protein K48-linked ubiquitination	4.768991e-4
GO:0007379	segment specification	4.959444e-4
GO:0006473	protein acetylation	5.003893e-4
GO:0042552	myelination	5.129499e-4
GO:0000302	response to reactive oxygen species	5.151327e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.210214e-4
GO:0045083	negative regulation of interleukin-12 biosynthetic process	5.210214e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	5.286192e-4
GO:0050684	regulation of mRNA processing	5.633094e-4
GO:0008612	peptidyl-lysine modification to hypusine	5.682109e-4
GO:0048596	embryonic camera-type eye morphogenesis	5.707773e-4
GO:0060765	regulation of androgen receptor signaling pathway	5.764207e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	5.811756e-4
GO:0003409	optic cup structural organization	5.814557e-4
GO:0021623	oculomotor nerve formation	5.814557e-4
GO:0003404	optic vesicle morphogenesis	5.814557e-4
GO:0007029	endoplasmic reticulum organization	6.166308e-4
GO:0007405	neuroblast proliferation	6.285553e-4
GO:0006325	chromatin organization	6.891723e-4
GO:0050995	negative regulation of lipid catabolic process	7.008902e-4
GO:0016570	histone modification	7.194781e-4
GO:0061003	positive regulation of dendritic spine morphogenesis	7.422199e-4
GO:0021773	striatal medium spiny neuron differentiation	7.532907e-4
GO:0010656	negative regulation of muscle cell apoptosis	8.007185e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	8.150651e-4
GO:0006936	muscle contraction	8.183067e-4
GO:0003334	keratinocyte development	8.186846e-4
GO:0032663	regulation of interleukin-2 production	8.269208e-4
GO:0042503	tyrosine phosphorylation of Stat3 protein	8.453187e-4
GO:0031947	negative regulation of glucocorticoid biosynthetic process	8.453187e-4
GO:0010985	negative regulation of lipoprotein particle clearance	8.501008e-4
GO:0051084	'de novo' posttranslational protein folding	8.573848e-4
GO:0015671	oxygen transport	8.739202e-4
GO:0032365	intracellular lipid transport	8.762809e-4
GO:0051099	positive regulation of binding	8.828152e-4
GO:0006551	leucine metabolic process	8.832559e-4
GO:0071281	cellular response to iron ion	8.846647e-4
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	8.846647e-4
GO:0021932	hindbrain radial glia guided cell migration	8.927740e-4
GO:0001963	synaptic transmission, dopaminergic	9.103062e-4
GO:0045905	positive regulation of translational termination	9.113978e-4
GO:0006452	translational frameshifting	9.113978e-4
GO:0045901	positive regulation of translational elongation	9.113978e-4
GO:0045843	negative regulation of striated muscle tissue development	9.356067e-4
GO:0003012	muscle system process	9.437330e-4
GO:0016569	covalent chromatin modification	9.471467e-4
GO:0048341	paraxial mesoderm formation	9.741535e-4
GO:0070170	regulation of tooth mineralization	9.879074e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.028036e-3
GO:0080090	regulation of primary metabolic process	1.048199e-3
GO:0048644	muscle organ morphogenesis	1.066215e-3
GO:0010556	regulation of macromolecule biosynthetic process	1.066747e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	1.076786e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	1.076786e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	1.076786e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.076786e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	1.076786e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.076786e-3
GO:0097107	postsynaptic density assembly	1.076786e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	1.076786e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	1.076786e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	1.076786e-3
GO:0070194	synaptonemal complex disassembly	1.123203e-3
GO:0002730	regulation of dendritic cell cytokine production	1.123203e-3
GO:0006402	mRNA catabolic process	1.143896e-3
GO:0035813	regulation of renal sodium excretion	1.175735e-3
GO:0010984	regulation of lipoprotein particle clearance	1.175735e-3
GO:0021604	cranial nerve structural organization	1.237017e-3
GO:0021904	dorsal/ventral neural tube patterning	1.255573e-3
GO:0071034	CUT catabolic process	1.277531e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.277531e-3
GO:0018394	peptidyl-lysine acetylation	1.300303e-3
GO:0002027	regulation of heart rate	1.301443e-3
GO:0015808	L-alanine transport	1.311386e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	1.390183e-3
GO:0019369	arachidonic acid metabolic process	1.413706e-3
GO:0031959	mineralocorticoid receptor signaling pathway	1.432868e-3
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.446616e-3
GO:0070252	actin-mediated cell contraction	1.448386e-3
GO:0090304	nucleic acid metabolic process	1.449014e-3
GO:0071845	cellular component disassembly at cellular level	1.509742e-3
GO:0010725	regulation of primitive erythrocyte differentiation	1.549888e-3
GO:0006780	uroporphyrinogen III biosynthetic process	1.549888e-3
GO:0034505	tooth mineralization	1.551411e-3
GO:0021861	forebrain radial glial cell differentiation	1.610775e-3
GO:0033146	regulation of estrogen receptor signaling pathway	1.631732e-3
GO:0051590	positive regulation of neurotransmitter transport	1.648789e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	1.648789e-3
GO:0043353	enucleate erythrocyte differentiation	1.652513e-3
GO:0061143	alveolar primary septum development	1.655955e-3
GO:0031076	embryonic camera-type eye development	1.667853e-3
GO:0018393	internal peptidyl-lysine acetylation	1.745327e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.750197e-3
GO:0060428	lung epithelium development	1.756822e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	1.793423e-3
GO:0019751	polyol metabolic process	1.867888e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.872583e-3
GO:0002830	positive regulation of type 2 immune response	1.880941e-3
GO:0006690	icosanoid metabolic process	1.882781e-3
GO:0043921	modulation by host of viral transcription	1.887726e-3
GO:0043633	polyadenylation-dependent RNA catabolic process	1.949999e-3
GO:0034276	kynurenic acid biosynthetic process	1.949999e-3
GO:0002534	cytokine production involved in inflammatory response	1.949999e-3
GO:0032924	activin receptor signaling pathway	1.985990e-3
GO:0030851	granulocyte differentiation	2.001971e-3
GO:0090245	axis elongation involved in somitogenesis	2.006651e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	2.006651e-3
GO:0061036	positive regulation of cartilage development	2.025685e-3
GO:0060040	retinal bipolar neuron differentiation	2.036591e-3
GO:0051013	microtubule severing	2.036591e-3
GO:0046782	regulation of viral transcription	2.038515e-3
GO:0051085	chaperone mediated protein folding requiring cofactor	2.045929e-3
GO:0071333	cellular response to glucose stimulus	2.065759e-3
GO:0051481	reduction of cytosolic calcium ion concentration	2.077754e-3
GO:2000377	regulation of reactive oxygen species metabolic process	2.083494e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	2.106918e-3
GO:0033235	positive regulation of protein sumoylation	2.139516e-3
GO:0006937	regulation of muscle contraction	2.151006e-3
GO:0071476	cellular hypotonic response	2.154536e-3
GO:0009880	embryonic pattern specification	2.155969e-3
GO:0045908	negative regulation of vasodilation	2.208422e-3
GO:0045819	positive regulation of glycogen catabolic process	2.208422e-3
GO:0030324	lung development	2.211975e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	2.236103e-3
GO:0072321	chaperone-mediated protein transport	2.236103e-3
GO:0009950	dorsal/ventral axis specification	2.237484e-3
GO:0048048	embryonic eye morphogenesis	2.244715e-3
GO:0022411	cellular component disassembly	2.311387e-3
GO:0018108	peptidyl-tyrosine phosphorylation	2.323374e-3
GO:0000738	DNA catabolic process, exonucleolytic	2.375498e-3
GO:0006921	cellular component disassembly involved in apoptosis	2.382005e-3
GO:0032693	negative regulation of interleukin-10 production	2.443825e-3
GO:0048635	negative regulation of muscle organ development	2.448573e-3
GO:0072070	loop of Henle development	2.476141e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.488340e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	2.531785e-3
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	2.531785e-3
GO:0030323	respiratory tube development	2.572619e-3
GO:0032928	regulation of superoxide anion generation	2.666663e-3
GO:0060973	cell migration involved in heart development	2.741199e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	2.748491e-3
GO:0048261	negative regulation of receptor-mediated endocytosis	2.922078e-3
GO:0042977	activation of JAK2 kinase activity	2.932533e-3
GO:0033275	actin-myosin filament sliding	2.936729e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	2.970574e-3
GO:0019226	transmission of nerve impulse	2.975011e-3
GO:0046580	negative regulation of Ras protein signal transduction	2.979287e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	2.982447e-3
GO:0070723	response to cholesterol	3.033949e-3
GO:0090231	regulation of spindle checkpoint	3.053844e-3
GO:0035641	locomotory exploration behavior	3.110343e-3
GO:0035409	histone H3-Y41 phosphorylation	3.159069e-3
GO:0008636	activation of caspase activity by protein phosphorylation	3.159069e-3
GO:0032239	regulation of nucleobase-containing compound transport	3.166514e-3
GO:0042554	superoxide anion generation	3.223565e-3
GO:0072210	metanephric nephron development	3.242153e-3
GO:0090102	cochlea development	3.253197e-3
GO:0006968	cellular defense response	3.278155e-3
GO:0021535	cell migration in hindbrain	3.343917e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	3.371564e-3
GO:0021785	branchiomotor neuron axon guidance	3.371564e-3
GO:0071322	cellular response to carbohydrate stimulus	3.376569e-3
GO:0048747	muscle fiber development	3.435098e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	3.478834e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.478834e-3
GO:0001973	adenosine receptor signaling pathway	3.497003e-3
GO:0010225	response to UV-C	3.513105e-3
GO:0006403	RNA localization	3.517168e-3
GO:0006546	glycine catabolic process	3.545383e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	3.574929e-3
GO:0072015	glomerular visceral epithelial cell development	3.576848e-3
GO:0014029	neural crest formation	3.576848e-3
GO:0072081	specification of nephron tubule identity	3.839957e-3
GO:0002339	B cell selection	3.839957e-3
GO:0061153	trachea gland development	3.839957e-3
GO:0010035	response to inorganic substance	3.995376e-3
GO:0061205	paramesonephric duct development	4.007018e-3
GO:0043388	positive regulation of DNA binding	4.042711e-3
GO:0019376	galactolipid catabolic process	4.076460e-3
GO:0043543	protein acylation	4.097863e-3
GO:0043044	ATP-dependent chromatin remodeling	4.120237e-3
GO:0072014	proximal tubule development	4.127063e-3
GO:0006342	chromatin silencing	4.224737e-3
GO:0051891	positive regulation of cardioblast differentiation	4.329262e-3
GO:0042699	follicle-stimulating hormone signaling pathway	4.518062e-3
GO:0006288	base-excision repair, DNA ligation	4.518062e-3
GO:0006940	regulation of smooth muscle contraction	4.525135e-3
GO:0006338	chromatin remodeling	4.528845e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	4.533106e-3
GO:0006654	phosphatidic acid biosynthetic process	4.634073e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	4.641763e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	4.732238e-3
GO:0060164	regulation of timing of neuron differentiation	4.907834e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	4.929578e-3
GO:0051058	negative regulation of small GTPase mediated signal transduction	4.957778e-3
GO:0050689	negative regulation of defense response to virus by host	4.984869e-3
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	4.984869e-3
GO:0048593	camera-type eye morphogenesis	5.006537e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	5.017098e-3
GO:0006475	internal protein amino acid acetylation	5.036243e-3
GO:0002579	positive regulation of antigen processing and presentation	5.061599e-3
GO:0060029	convergent extension involved in organogenesis	5.062349e-3
GO:0016075	rRNA catabolic process	5.078962e-3
GO:0034720	histone H3-K4 demethylation	5.078962e-3
GO:0010595	positive regulation of endothelial cell migration	5.152504e-3
GO:0008635	activation of caspase activity by cytochrome c	5.201064e-3
GO:0018279	protein N-linked glycosylation via asparagine	5.240255e-3
GO:0090257	regulation of muscle system process	5.368060e-3
GO:0006289	nucleotide-excision repair	5.407104e-3
GO:0060325	face morphogenesis	5.471368e-3
GO:0043966	histone H3 acetylation	5.471675e-3
GO:0030223	neutrophil differentiation	5.509194e-3
GO:0021557	oculomotor nerve development	5.509194e-3
GO:0034421	post-translational protein acetylation	5.538820e-3
GO:0045110	intermediate filament bundle assembly	5.538820e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	5.538820e-3
GO:0060032	notochord regression	5.561061e-3
GO:0048382	mesendoderm development	5.561061e-3
GO:0051586	positive regulation of dopamine uptake	5.561061e-3
GO:2000178	negative regulation of neural precursor cell proliferation	5.562645e-3
GO:0090274	positive regulation of somatostatin secretion	5.646817e-3
GO:0071028	nuclear mRNA surveillance	5.646817e-3
GO:2000706	negative regulation of dense core granule biogenesis	5.646817e-3
GO:2000798	negative regulation of amniotic stem cell differentiation	5.646817e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	5.646817e-3
GO:0048047	mating behavior, sex discrimination	5.646817e-3
GO:0002124	territorial aggressive behavior	5.646817e-3
GO:0043538	regulation of actin phosphorylation	5.646817e-3
GO:0043312	neutrophil degranulation	5.680138e-3
GO:0050882	voluntary musculoskeletal movement	5.687334e-3
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	5.687334e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	5.687334e-3
GO:0022007	convergent extension involved in neural plate elongation	5.687334e-3
GO:0002175	protein localization to paranode region of axon	5.687334e-3
GO:0003208	cardiac ventricle morphogenesis	5.687819e-3
GO:0006355	regulation of transcription, DNA-dependent	5.812189e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	5.813389e-3
GO:0051252	regulation of RNA metabolic process	5.819332e-3
GO:0035887	aortic smooth muscle cell differentiation	5.996232e-3
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	6.001522e-3
GO:0042989	sequestering of actin monomers	6.039654e-3
GO:0045814	negative regulation of gene expression, epigenetic	6.319949e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	6.336144e-3
GO:0071895	odontoblast differentiation	6.340862e-3
GO:0032222	regulation of synaptic transmission, cholinergic	6.340862e-3
GO:0009247	glycolipid biosynthetic process	6.388557e-3
GO:0044265	cellular macromolecule catabolic process	6.398529e-3
GO:0060235	lens induction in camera-type eye	6.442880e-3
GO:0016573	histone acetylation	6.457998e-3
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	6.634152e-3
GO:0001516	prostaglandin biosynthetic process	6.680702e-3
GO:0006487	protein N-linked glycosylation	6.699420e-3
GO:0010557	positive regulation of macromolecule biosynthetic process	6.768718e-3
GO:0051851	modification by host of symbiont morphology or physiology	6.773417e-3
GO:0048143	astrocyte activation	6.797530e-3
GO:0051403	stress-activated MAPK cascade	6.826698e-3
GO:0006659	phosphatidylserine biosynthetic process	6.826698e-3
GO:2000425	regulation of apoptotic cell clearance	6.862494e-3
GO:0031328	positive regulation of cellular biosynthetic process	6.923346e-3
GO:0072112	glomerular visceral epithelial cell differentiation	6.964644e-3
GO:0001508	regulation of action potential	6.998385e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	7.010859e-3
GO:0031427	response to methotrexate	7.010859e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	7.010859e-3
GO:0032092	positive regulation of protein binding	7.096523e-3
GO:0043491	protein kinase B signaling cascade	7.161449e-3
GO:2000741	positive regulation of mesenchymal stem cell differentiation	7.171206e-3
GO:0001678	cellular glucose homeostasis	7.199342e-3
GO:0033119	negative regulation of RNA splicing	7.500391e-3
GO:0050905	neuromuscular process	7.530405e-3
GO:0035640	exploration behavior	7.583652e-3
GO:0071470	cellular response to osmotic stress	7.668251e-3
GO:0060689	cell differentiation involved in salivary gland development	7.687094e-3
GO:0046007	negative regulation of activated T cell proliferation	7.687094e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	7.687094e-3
GO:0001707	mesoderm formation	7.689491e-3
GO:0035261	external genitalia morphogenesis	7.841484e-3
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	7.862646e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	7.862646e-3
GO:0046670	positive regulation of retinal cell programmed cell death	7.862646e-3
GO:0006550	isoleucine catabolic process	7.882134e-3
GO:0009098	leucine biosynthetic process	7.882134e-3
GO:0003273	cell migration involved in endocardial cushion formation	7.882134e-3
GO:0019400	alditol metabolic process	7.899648e-3
GO:0033233	regulation of protein sumoylation	8.035809e-3
GO:0045216	cell-cell junction organization	8.109469e-3
GO:0009891	positive regulation of biosynthetic process	8.126267e-3
GO:0007369	gastrulation	8.131055e-3
GO:0010594	regulation of endothelial cell migration	8.235400e-3
GO:0042036	negative regulation of cytokine biosynthetic process	8.258241e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	8.312491e-3
GO:0003171	atrioventricular valve development	8.367992e-3
GO:0048069	eye pigmentation	8.391181e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	8.537985e-3
GO:0051298	centrosome duplication	8.627916e-3
GO:0045655	regulation of monocyte differentiation	8.647761e-3
GO:0048332	mesoderm morphogenesis	8.782909e-3
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	8.807007e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	8.816764e-3
GO:0070483	detection of hypoxia	8.816764e-3
GO:0007089	traversing start control point of mitotic cell cycle	8.816764e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	8.816764e-3
GO:0048167	regulation of synaptic plasticity	8.830694e-3
GO:0034509	centromeric core chromatin assembly	8.868603e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	8.868603e-3
GO:0008016	regulation of heart contraction	9.047490e-3
GO:0042335	cuticle development	9.054826e-3
GO:0070370	cellular heat acclimation	9.054826e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	9.054826e-3
GO:0032077	positive regulation of deoxyribonuclease activity	9.054826e-3
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.054826e-3
GO:0034589	hydroxyproline transport	9.070990e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	9.070990e-3
GO:0015826	threonine transport	9.070990e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	9.122164e-3
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	9.277321e-3
GO:0002827	positive regulation of T-helper 1 type immune response	9.277321e-3
GO:0072655	establishment of protein localization in mitochondrion	9.331570e-3
GO:0001961	positive regulation of cytokine-mediated signaling pathway	9.475851e-3
GO:0009913	epidermal cell differentiation	9.525691e-3
GO:0043270	positive regulation of ion transport	9.547614e-3
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	9.724514e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	9.724514e-3
GO:2000243	positive regulation of reproductive process	9.740822e-3
GO:0060088	auditory receptor cell stereocilium organization	9.935841e-3
GO:0003214	cardiac left ventricle morphogenesis	9.978699e-3
GO:0033153	T cell receptor V(D)J recombination	1.009872e-2
GO:0060743	epithelial cell maturation involved in prostate gland development	1.011376e-2
GO:0002344	B cell affinity maturation	1.011376e-2
GO:0072092	ureteric bud invasion	1.020559e-2
GO:0030033	microvillus assembly	1.020559e-2
GO:0006651	diacylglycerol biosynthetic process	1.020559e-2
GO:0042026	protein refolding	1.026184e-2
GO:0001886	endothelial cell morphogenesis	1.026184e-2
GO:0061004	pattern specification involved in kidney development	1.050897e-2
GO:0060255	regulation of macromolecule metabolic process	1.057593e-2
GO:0032516	positive regulation of phosphoprotein phosphatase activity	1.071762e-2
GO:0006693	prostaglandin metabolic process	1.076999e-2
GO:0042475	odontogenesis of dentine-containing tooth	1.079397e-2
GO:0010467	gene expression	1.085219e-2
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.095696e-2
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	1.122541e-2
GO:0002724	regulation of T cell cytokine production	1.140519e-2
GO:0002093	auditory receptor cell morphogenesis	1.141223e-2
GO:0021516	dorsal spinal cord development	1.154883e-2
GO:0007043	cell-cell junction assembly	1.157303e-2