Novel motif:110

name:	motif110_AGTCGCAGCG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	4.462687e-10
GO:0019087	transformation of host cell by virus	8.748418e-10
GO:0019048	virus-host interaction	2.691059e-8
GO:0016569	covalent chromatin modification	3.636327e-8
GO:0042254	ribosome biogenesis	4.809796e-8
GO:0016570	histone modification	5.758828e-8
GO:0042255	ribosome assembly	7.019678e-8
GO:0018026	peptidyl-lysine monomethylation	1.740110e-7
GO:0018022	peptidyl-lysine methylation	1.864553e-7
GO:0043414	macromolecule methylation	3.691080e-7
GO:0002149	hypochlorous acid biosynthetic process	3.887319e-7
GO:0090141	positive regulation of mitochondrial fission	3.906543e-7
GO:0006369	termination of RNA polymerase II transcription	4.131103e-7
GO:0018027	peptidyl-lysine dimethylation	6.696126e-7
GO:0061157	mRNA destabilization	8.834876e-7
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	8.834876e-7
GO:0006479	protein methylation	1.104506e-6
GO:0034551	mitochondrial respiratory chain complex III assembly	1.458925e-6
GO:0016571	histone methylation	1.525280e-6
GO:0002679	respiratory burst involved in defense response	1.542216e-6
GO:0032042	mitochondrial DNA metabolic process	1.603504e-6
GO:0010523	negative regulation of calcium ion transport into cytosol	2.377516e-6
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4.243192e-6
GO:0051013	microtubule severing	6.293816e-6
GO:2000786	positive regulation of autophagic vacuole assembly	6.311356e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	6.611140e-6
GO:0090140	regulation of mitochondrial fission	6.919786e-6
GO:0065002	intracellular protein transmembrane transport	9.002538e-6
GO:0006264	mitochondrial DNA replication	9.436916e-6
GO:0021526	medial motor column neuron differentiation	1.202417e-5
GO:0048102	autophagic cell death	1.294042e-5
GO:0018119	peptidyl-cysteine S-nitrosylation	1.345093e-5
GO:0001830	trophectodermal cell fate commitment	1.434184e-5
GO:0044088	regulation of vacuole organization	1.744306e-5
GO:0034969	histone arginine methylation	1.938563e-5
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.977129e-5
GO:0070079	histone H4-R3 demethylation	3.002519e-5
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	3.002519e-5
GO:0070078	histone H3-R2 demethylation	3.002519e-5
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	3.478237e-5
GO:0046416	D-amino acid metabolic process	3.478237e-5
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	3.478237e-5
GO:0042093	T-helper cell differentiation	3.667192e-5
GO:0071169	establishment of protein localization to chromatin	3.784259e-5
GO:0070979	protein K11-linked ubiquitination	4.018530e-5
GO:0018198	peptidyl-cysteine modification	4.366392e-5
GO:0071673	positive regulation of smooth muscle cell chemotaxis	4.620652e-5
GO:0032383	regulation of intracellular cholesterol transport	4.720919e-5
GO:0045415	negative regulation of interleukin-8 biosynthetic process	4.971147e-5
GO:0071460	cellular response to cell-matrix adhesion	5.279147e-5
GO:0031442	positive regulation of mRNA 3'-end processing	5.312794e-5
GO:0043985	histone H4-R3 methylation	5.453193e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.607590e-5
GO:0090311	regulation of protein deacetylation	5.771347e-5
GO:0035307	positive regulation of protein dephosphorylation	5.850745e-5
GO:0016577	histone demethylation	5.951441e-5
GO:0019428	allantoin biosynthetic process	6.313020e-5
GO:0071279	cellular response to cobalt ion	6.313020e-5
GO:0010637	negative regulation of mitochondrial fusion	6.313020e-5
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	6.702795e-5
GO:0090344	negative regulation of cell aging	6.769986e-5
GO:0043084	penile erection	7.340071e-5
GO:0007288	sperm axoneme assembly	8.169045e-5
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	8.177600e-5
GO:2000143	negative regulation of transcription initiation, DNA-dependent	8.286316e-5
GO:0006478	peptidyl-tyrosine sulfation	8.787854e-5
GO:0072393	microtubule anchoring at microtubule organizing center	8.955102e-5
GO:0035304	regulation of protein dephosphorylation	9.303906e-5
GO:0035364	thymine transport	9.818835e-5
GO:0035344	hypoxanthine transport	9.818835e-5
GO:0015854	guanine transport	9.818835e-5
GO:0006481	C-terminal protein methylation	1.010362e-4
GO:0060999	positive regulation of dendritic spine development	1.043713e-4
GO:0035306	positive regulation of dephosphorylation	1.079434e-4
GO:0046684	response to pyrethroid	1.100939e-4
GO:0060033	anatomical structure regression	1.152929e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.249411e-4
GO:0016072	rRNA metabolic process	1.297872e-4
GO:0061013	regulation of mRNA catabolic process	1.409361e-4
GO:0090103	cochlea morphogenesis	1.446809e-4
GO:0006364	rRNA processing	1.493648e-4
GO:0090312	positive regulation of protein deacetylation	1.544977e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.629388e-4
GO:0009785	blue light signaling pathway	1.634060e-4
GO:0051457	maintenance of protein location in nucleus	1.726885e-4
GO:0008298	intracellular mRNA localization	1.747651e-4
GO:0061032	visceral serous pericardium development	1.789691e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.789691e-4
GO:0035606	peptidyl-cysteine S-trans-nitrosylation	1.789691e-4
GO:0070179	D-serine biosynthetic process	1.870221e-4
GO:0031118	rRNA pseudouridine synthesis	1.870221e-4
GO:0010735	positive regulation of transcription via serum response element binding	1.917276e-4
GO:0045662	negative regulation of myoblast differentiation	1.993627e-4
GO:0051573	negative regulation of histone H3-K9 methylation	2.127304e-4
GO:0043949	regulation of cAMP-mediated signaling	2.269987e-4
GO:0006482	protein demethylation	2.281054e-4
GO:0021986	habenula development	2.558463e-4
GO:0035470	positive regulation of vascular wound healing	2.563638e-4
GO:0051028	mRNA transport	2.603037e-4
GO:0034968	histone lysine methylation	2.628700e-4
GO:0051290	protein heterotetramerization	2.696266e-4
GO:0046732	active induction of host immune response by virus	2.733341e-4
GO:0060923	cardiac muscle cell fate commitment	2.784274e-4
GO:0072385	minus-end-directed organelle transport along microtubule	2.797884e-4
GO:0071294	cellular response to zinc ion	2.808872e-4
GO:0006406	mRNA export from nucleus	2.810598e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	3.015989e-4
GO:0016598	protein arginylation	3.129413e-4
GO:0048050	post-embryonic eye morphogenesis	3.178407e-4
GO:0006403	RNA localization	3.238276e-4
GO:0035329	hippo signaling cascade	3.293696e-4
GO:0043367	CD4-positive, alpha-beta T cell differentiation	3.371186e-4
GO:0042766	nucleosome mobilization	3.390389e-4
GO:0008078	mesodermal cell migration	3.414144e-4
GO:0043951	negative regulation of cAMP-mediated signaling	3.420416e-4
GO:0032094	response to food	4.121290e-4
GO:0046730	induction of host immune response by virus	4.346373e-4
GO:0090342	regulation of cell aging	4.346728e-4
GO:0008535	respiratory chain complex IV assembly	4.354614e-4
GO:0000389	nuclear mRNA 3'-splice site recognition	4.398543e-4
GO:0006188	IMP biosynthetic process	4.737995e-4
GO:0001840	neural plate development	5.114825e-4
GO:0090102	cochlea development	5.223049e-4
GO:0000414	regulation of histone H3-K36 methylation	5.447315e-4
GO:0019088	immortalization of host cell by virus	5.447579e-4
GO:0006231	dTMP biosynthetic process	5.447579e-4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	5.457112e-4
GO:0009817	defense response to fungus, incompatible interaction	5.457112e-4
GO:0061014	positive regulation of mRNA catabolic process	5.476073e-4
GO:2001037	positive regulation of tongue muscle cell differentiation	6.017496e-4
GO:0097152	mesenchymal cell apoptosis	6.017496e-4
GO:0046078	dUMP metabolic process	6.017496e-4
GO:0060982	coronary artery morphogenesis	6.017496e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	6.047557e-4
GO:0001975	response to amphetamine	6.276898e-4
GO:0006844	acyl carnitine transport	6.345606e-4
GO:0006430	lysyl-tRNA aminoacylation	6.345606e-4
GO:0072166	posterior mesonephric tubule development	6.547065e-4
GO:0060242	contact inhibition	6.547065e-4
GO:0021644	vagus nerve morphogenesis	6.547065e-4
GO:0090129	positive regulation of synapse maturation	6.746095e-4
GO:0015886	heme transport	6.830131e-4
GO:0060744	mammary gland branching involved in thelarche	6.905867e-4
GO:0048268	clathrin coat assembly	6.999203e-4
GO:0035814	negative regulation of renal sodium excretion	7.022778e-4
GO:0022613	ribonucleoprotein complex biogenesis	7.036904e-4
GO:0010742	macrophage derived foam cell differentiation	7.556927e-4
GO:0031063	regulation of histone deacetylation	7.572238e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.900137e-4
GO:0048210	Golgi vesicle fusion to target membrane	7.985278e-4
GO:0007182	common-partner SMAD protein phosphorylation	8.396633e-4
GO:0016241	regulation of macroautophagy	8.468638e-4
GO:0002513	tolerance induction to self antigen	8.568943e-4
GO:0035710	CD4-positive, alpha-beta T cell activation	8.753752e-4
GO:0051102	DNA ligation involved in DNA recombination	9.065106e-4
GO:0009405	pathogenesis	9.114235e-4
GO:0031558	induction of apoptosis in response to chemical stimulus	9.572535e-4
GO:0009637	response to blue light	9.869607e-4
GO:0032802	low-density lipoprotein particle receptor catabolic process	9.979019e-4
GO:0010626	negative regulation of Schwann cell proliferation	1.002457e-3
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	1.012198e-3
GO:0006529	asparagine biosynthetic process	1.072808e-3
GO:0001842	neural fold formation	1.104037e-3
GO:0034470	ncRNA processing	1.124372e-3
GO:0051645	Golgi localization	1.197766e-3
GO:0045064	T-helper 2 cell differentiation	1.197766e-3
GO:0002315	marginal zone B cell differentiation	1.197766e-3
GO:0031427	response to methotrexate	1.205834e-3
GO:0043932	ossification involved in bone remodeling	1.222789e-3
GO:0006177	GMP biosynthetic process	1.269276e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.466297e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.491875e-3
GO:0003329	pancreatic PP cell fate commitment	1.588403e-3
GO:0070734	histone H3-K27 methylation	1.588403e-3
GO:0003326	pancreatic A cell fate commitment	1.588403e-3
GO:0040040	thermosensory behavior	1.730157e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.730157e-3
GO:0002293	alpha-beta T cell differentiation involved in immune response	1.742742e-3
GO:0060976	coronary vasculature development	1.744791e-3
GO:0007509	mesoderm migration involved in gastrulation	1.777196e-3
GO:0033146	regulation of estrogen receptor signaling pathway	1.777827e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	1.805855e-3
GO:0090128	regulation of synapse maturation	1.845475e-3
GO:0097045	phosphatidylserine exposure on blood platelet	1.916134e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.916134e-3
GO:0030704	vitelline membrane formation	1.916134e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	1.916134e-3
GO:0042274	ribosomal small subunit biogenesis	1.956522e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	1.961051e-3
GO:0006670	sphingosine metabolic process	1.987797e-3
GO:0033233	regulation of protein sumoylation	2.052672e-3
GO:0006533	aspartate catabolic process	2.071143e-3
GO:0010835	regulation of protein ADP-ribosylation	2.121699e-3
GO:0035425	autocrine signaling	2.121699e-3
GO:0001839	neural plate morphogenesis	2.155979e-3
GO:0090303	positive regulation of wound healing	2.176232e-3
GO:0031440	regulation of mRNA 3'-end processing	2.200668e-3
GO:0010765	positive regulation of sodium ion transport	2.278917e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2.308956e-3
GO:0006287	base-excision repair, gap-filling	2.308956e-3
GO:0021506	anterior neuropore closure	2.315491e-3
GO:0033692	cellular polysaccharide biosynthetic process	2.409085e-3
GO:0007184	SMAD protein import into nucleus	2.421461e-3
GO:0007549	dosage compensation	2.490492e-3
GO:0031065	positive regulation of histone deacetylation	2.548270e-3
GO:0006346	methylation-dependent chromatin silencing	2.559748e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	2.614462e-3
GO:0071671	regulation of smooth muscle cell chemotaxis	2.636229e-3
GO:0006405	RNA export from nucleus	2.703730e-3
GO:0035852	horizontal cell localization	2.705232e-3
GO:0080009	mRNA methylation	2.705232e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	2.705232e-3
GO:0035849	nephric duct elongation	2.705232e-3
GO:0035847	uterine epithelium development	2.705232e-3
GO:0006781	succinyl-CoA pathway	2.705232e-3
GO:0035502	metanephric ureteric bud development	2.705232e-3
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	2.705232e-3
GO:0035846	oviduct epithelium development	2.705232e-3
GO:0045329	carnitine biosynthetic process	2.729287e-3
GO:0015862	uridine transport	2.866924e-3
GO:0006984	ER-nucleus signaling pathway	2.905035e-3
GO:0034401	regulation of transcription by chromatin organization	2.911393e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	2.911393e-3
GO:0043174	nucleoside salvage	2.946091e-3
GO:0001829	trophectodermal cell differentiation	2.948048e-3
GO:0051586	positive regulation of dopamine uptake	3.092025e-3
GO:0021930	cerebellar granule cell precursor proliferation	3.092025e-3
GO:0002268	follicular dendritic cell differentiation	3.128092e-3
GO:0035247	peptidyl-arginine omega-N-methylation	3.163193e-3
GO:0032060	bleb assembly	3.163193e-3
GO:0060009	Sertoli cell development	3.272695e-3
GO:0021784	postganglionic parasympathetic nervous system development	3.286589e-3
GO:0048486	parasympathetic nervous system development	3.336608e-3
GO:0021568	rhombomere 2 development	3.396087e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	3.431521e-3
GO:0045403	negative regulation of interleukin-4 biosynthetic process	3.431521e-3
GO:2000002	negative regulation of DNA damage checkpoint	3.431521e-3
GO:0060377	negative regulation of mast cell differentiation	3.431521e-3
GO:0021588	cerebellum formation	3.431521e-3
GO:0021551	central nervous system morphogenesis	3.431521e-3
GO:0003192	mitral valve formation	3.431521e-3
GO:0002295	T-helper cell lineage commitment	3.431521e-3
GO:0003195	tricuspid valve formation	3.431521e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	3.507598e-3
GO:0035803	egg coat formation	3.516074e-3
GO:0007100	mitotic centrosome separation	3.516074e-3
GO:0003175	tricuspid valve development	3.737739e-3
GO:0040015	negative regulation of multicellular organism growth	3.889655e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	3.895218e-3
GO:0000416	positive regulation of histone H3-K36 methylation	3.895218e-3
GO:0071281	cellular response to iron ion	3.931692e-3
GO:0043097	pyrimidine nucleoside salvage	3.988532e-3
GO:0022007	convergent extension involved in neural plate elongation	4.133766e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	4.280107e-3
GO:0046670	positive regulation of retinal cell programmed cell death	4.280107e-3
GO:0032077	positive regulation of deoxyribonuclease activity	4.280107e-3
GO:0042256	mature ribosome assembly	4.283652e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	4.283652e-3
GO:0006301	postreplication repair	4.283985e-3
GO:0033058	directional locomotion	4.377237e-3
GO:0034770	histone H4-K20 methylation	4.388601e-3
GO:0015789	UDP-N-acetylgalactosamine transport	4.465280e-3
GO:0015787	UDP-glucuronic acid transport	4.465280e-3
GO:0050658	RNA transport	4.488775e-3
GO:0000002	mitochondrial genome maintenance	4.670718e-3
GO:0030433	ER-associated protein catabolic process	4.695090e-3
GO:0072298	regulation of metanephric glomerulus development	4.755816e-3
GO:0045351	type I interferon biosynthetic process	4.756093e-3
GO:0006730	one-carbon metabolic process	4.793505e-3
GO:0035725	sodium ion transmembrane transport	4.802170e-3
GO:0046499	S-adenosylmethioninamine metabolic process	5.121262e-3
GO:0033057	multicellular organismal reproductive behavior	5.188445e-3
GO:0010701	positive regulation of norepinephrine secretion	5.201996e-3
GO:0010756	positive regulation of plasminogen activation	5.237435e-3
GO:0006423	cysteinyl-tRNA aminoacylation	5.397777e-3
GO:0060455	negative regulation of gastric acid secretion	5.397777e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	5.397777e-3
GO:0010225	response to UV-C	5.404788e-3
GO:0000387	spliceosomal snRNP assembly	5.407399e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	5.408803e-3
GO:0060711	labyrinthine layer development	5.430105e-3
GO:0042711	maternal behavior	5.455325e-3
GO:0009437	carnitine metabolic process	5.488590e-3
GO:0021615	glossopharyngeal nerve morphogenesis	5.495578e-3
GO:0006610	ribosomal protein import into nucleus	5.536567e-3
GO:0022415	viral reproductive process	5.549848e-3
GO:0045136	development of secondary sexual characteristics	5.586135e-3
GO:0003311	pancreatic D cell differentiation	5.614773e-3
GO:0090104	pancreatic E cell differentiation	5.614773e-3
GO:0000027	ribosomal large subunit assembly	5.614773e-3
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	5.718728e-3
GO:0032259	methylation	5.806815e-3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	5.959340e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	5.959340e-3
GO:0045472	response to ether	5.959340e-3
GO:0061302	smooth muscle cell-matrix adhesion	5.959340e-3
GO:0009162	deoxyribonucleoside monophosphate metabolic process	6.081920e-3
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	6.126807e-3
GO:0032244	positive regulation of nucleoside transport	6.156350e-3
GO:0032900	negative regulation of neurotrophin production	6.156350e-3
GO:0070925	organelle assembly	6.301795e-3
GO:0071542	dopaminergic neuron differentiation	6.337274e-3
GO:0014037	Schwann cell differentiation	6.358717e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	6.417419e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	6.417419e-3
GO:0010836	negative regulation of protein ADP-ribosylation	6.417419e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	6.457761e-3
GO:0034970	histone H3-R2 methylation	6.594852e-3
GO:0030513	positive regulation of BMP signaling pathway	6.623807e-3
GO:0046784	intronless viral mRNA export from host nucleus	6.681651e-3
GO:0032926	negative regulation of activin receptor signaling pathway	6.681651e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6.723181e-3
GO:0010498	proteasomal protein catabolic process	6.795613e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	6.837192e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	7.121601e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	7.179283e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	7.179283e-3
GO:0071843	cellular component biogenesis at cellular level	7.335075e-3
GO:0060017	parathyroid gland development	7.595681e-3
GO:0061084	negative regulation of protein refolding	7.689192e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	7.689192e-3
GO:0006004	fucose metabolic process	7.887068e-3
GO:0071585	detoxification of cadmium ion	7.973502e-3
GO:0032264	IMP salvage	7.973502e-3
GO:0032263	GMP salvage	7.973502e-3
GO:0010561	negative regulation of glycoprotein biosynthetic process	8.021330e-3
GO:0006171	cAMP biosynthetic process	8.108122e-3
GO:0016568	chromatin modification	8.114151e-3
GO:0060466	activation of meiosis involved in egg activation	8.151684e-3
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	8.247878e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	8.247878e-3
GO:0001941	postsynaptic membrane organization	8.404457e-3
GO:0021819	layer formation in cerebral cortex	8.427207e-3
GO:0016925	protein sumoylation	8.467904e-3
GO:0046037	GMP metabolic process	8.529071e-3
GO:0042053	regulation of dopamine metabolic process	8.645244e-3
GO:0071280	cellular response to copper ion	8.653347e-3
GO:0016559	peroxisome fission	8.653347e-3
GO:0000413	protein peptidyl-prolyl isomerization	8.678662e-3
GO:0070534	protein K63-linked ubiquitination	8.789049e-3
GO:0046796	viral genome transport in host cell	8.821411e-3
GO:0043519	regulation of myosin II filament organization	8.821411e-3
GO:0007406	negative regulation of neuroblast proliferation	9.054373e-3
GO:0050775	positive regulation of dendrite morphogenesis	9.097419e-3
GO:0006379	mRNA cleavage	9.159141e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	9.171737e-3
GO:0070988	demethylation	9.294646e-3
GO:0060998	regulation of dendritic spine development	9.294850e-3
GO:0060136	embryonic process involved in female pregnancy	9.309227e-3
GO:0050689	negative regulation of defense response to virus by host	9.423584e-3
GO:0046174	polyol catabolic process	9.423584e-3
GO:0009263	deoxyribonucleotide biosynthetic process	9.468404e-3
GO:0043148	mitotic spindle stabilization	9.475189e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	9.475189e-3
GO:0006545	glycine biosynthetic process	9.499049e-3
GO:0006544	glycine metabolic process	9.654702e-3
GO:0006013	mannose metabolic process	1.002757e-2
GO:0043353	enucleate erythrocyte differentiation	1.018701e-2
GO:0010822	positive regulation of mitochondrion organization	1.023011e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.038796e-2
GO:0010722	regulation of ferrochelatase activity	1.038796e-2
GO:0003327	type B pancreatic cell fate commitment	1.038796e-2
GO:0050685	positive regulation of mRNA processing	1.045072e-2
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.047852e-2
GO:0030968	endoplasmic reticulum unfolded protein response	1.051121e-2
GO:0051463	negative regulation of cortisol secretion	1.091870e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.091870e-2
GO:0060125	negative regulation of growth hormone secretion	1.091870e-2
GO:0034971	histone H3-R17 methylation	1.091870e-2
GO:0000088	mitotic prophase	1.091870e-2
GO:0006178	guanine salvage	1.091870e-2
GO:0046038	GMP catabolic process	1.091870e-2
GO:0030851	granulocyte differentiation	1.097494e-2
GO:0060623	regulation of chromosome condensation	1.102730e-2
GO:0071283	cellular response to iron(III) ion	1.102730e-2
GO:2000009	negative regulation of protein localization at cell surface	1.102730e-2
GO:0046680	response to DDT	1.102730e-2
GO:0018872	arsonoacetate metabolic process	1.102730e-2
GO:0043456	regulation of pentose-phosphate shunt	1.102730e-2
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	1.102730e-2
GO:0014733	regulation of skeletal muscle adaptation	1.124869e-2
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.130869e-2
GO:0048561	establishment of organ orientation	1.165504e-2
GO:0060821	inactivation of X chromosome by DNA methylation	1.165504e-2
GO:0019478	D-amino acid catabolic process	1.165504e-2
GO:0019405	alditol catabolic process	1.165504e-2
GO:0002438	acute inflammatory response to antigenic stimulus	1.165504e-2
GO:0007343	egg activation	1.170764e-2
GO:0042414	epinephrine metabolic process	1.183191e-2
GO:0003094	glomerular filtration	1.183191e-2
GO:0071514	genetic imprinting	1.184756e-2
GO:0015827	tryptophan transport	1.192131e-2
GO:0061099	negative regulation of protein tyrosine kinase activity	1.231214e-2
GO:2000772	regulation of cellular senescence	1.269233e-2
GO:0018216	peptidyl-arginine methylation	1.273905e-2
GO:0042069	regulation of catecholamine metabolic process	1.281181e-2
GO:0035928	rRNA import into mitochondrion	1.322126e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.329506e-2
GO:0034660	ncRNA metabolic process	1.330411e-2
GO:0051567	histone H3-K9 methylation	1.349556e-2
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	1.352796e-2
GO:0035246	peptidyl-arginine N-methylation	1.372482e-2
GO:0044003	modification by symbiont of host morphology or physiology	1.379576e-2
GO:0051590	positive regulation of neurotransmitter transport	1.385587e-2
GO:0061100	lung neuroendocrine cell differentiation	1.391699e-2
GO:0061102	stomach neuroendocrine cell differentiation	1.391699e-2
GO:0071259	cellular response to magnetism	1.391699e-2
GO:0061104	adrenal chromaffin cell differentiation	1.391699e-2
GO:0061103	carotid body glomus cell differentiation	1.391699e-2
GO:0060165	regulation of timing of subpallium neuron differentiation	1.391699e-2
GO:0003359	noradrenergic neuron fate commitment	1.391699e-2
GO:0007400	neuroblast fate determination	1.391699e-2
GO:0008292	acetylcholine biosynthetic process	1.391699e-2
GO:0060163	subpallium neuron fate commitment	1.391699e-2
GO:0021932	hindbrain radial glia guided cell migration	1.407104e-2
GO:0014044	Schwann cell development	1.419912e-2
GO:0035372	protein localization to microtubule	1.425864e-2
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.429356e-2
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.429356e-2
GO:0043973	histone H3-K4 acetylation	1.429356e-2
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.429356e-2
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	1.431933e-2
GO:0009440	cyanate catabolic process	1.431933e-2
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.434935e-2
GO:0042273	ribosomal large subunit biogenesis	1.478905e-2
GO:0042074	cell migration involved in gastrulation	1.501002e-2
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.501175e-2
GO:0043045	DNA methylation involved in embryo development	1.501175e-2
GO:0033148	positive regulation of estrogen receptor signaling pathway	1.547183e-2
GO:0061003	positive regulation of dendritic spine morphogenesis	1.596468e-2
GO:0032025	response to cobalt ion	1.631397e-2
GO:0045836	positive regulation of meiosis	1.637303e-2
GO:0044342	type B pancreatic cell proliferation	1.644821e-2
GO:0015680	intracellular copper ion transport	1.644821e-2
GO:0010918	positive regulation of mitochondrial membrane potential	1.644821e-2
GO:0060977	coronary vasculature morphogenesis	1.694947e-2
GO:0006085	acetyl-CoA biosynthetic process	1.694947e-2
GO:0021542	dentate gyrus development	1.708234e-2
GO:0010988	regulation of low-density lipoprotein particle clearance	1.718946e-2
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	1.726381e-2
GO:0016561	protein import into peroxisome matrix, translocation	1.726381e-2
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.740769e-2
GO:0001825	blastocyst formation	1.744238e-2
GO:0018205	peptidyl-lysine modification	1.746089e-2
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.747420e-2
GO:0051030	snRNA transport	1.768737e-2
GO:0006189	'de novo' IMP biosynthetic process	1.768737e-2
GO:0035511	oxidative DNA demethylation	1.776245e-2
GO:0045792	negative regulation of cell size	1.784010e-2
GO:0035308	negative regulation of protein dephosphorylation	1.806076e-2
GO:0019254	carnitine metabolic process, CoA-linked	1.818664e-2
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	1.826980e-2
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	1.826980e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.838941e-2
GO:0033120	positive regulation of RNA splicing	1.877064e-2
GO:0016926	protein desumoylation	1.877262e-2
GO:0005978	glycogen biosynthetic process	1.890003e-2
GO:0009186	deoxyribonucleoside diphosphate metabolic process	1.914494e-2
GO:0031557	induction of programmed cell death in response to chemical stimulus	1.931640e-2
GO:0043308	eosinophil degranulation	1.946539e-2
GO:0042796	snRNA transcription from RNA polymerase III promoter	1.946539e-2
GO:0046674	induction of retinal programmed cell death	1.946539e-2
GO:0051885	positive regulation of anagen	1.946539e-2
GO:0042795	snRNA transcription from RNA polymerase II promoter	1.946539e-2
GO:0048597	post-embryonic camera-type eye morphogenesis	1.946539e-2
GO:0001777	T cell homeostatic proliferation	1.946539e-2
GO:0002352	B cell negative selection	1.946539e-2
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.946539e-2
GO:0014835	myoblast cell differentiation involved in skeletal muscle regeneration	1.946539e-2
GO:0001579	medium-chain fatty acid transport	1.946539e-2
GO:0021764	amygdala development	1.946539e-2
GO:0032976	release of matrix enzymes from mitochondria	1.946539e-2
GO:0070904	transepithelial L-ascorbic acid transport	2.001226e-2
GO:0046604	positive regulation of mitotic centrosome separation	2.023230e-2
GO:0034351	negative regulation of glial cell apoptosis	2.023230e-2
GO:0045200	establishment of neuroblast polarity	2.023230e-2
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	2.026286e-2
GO:0050748	negative regulation of lipoprotein metabolic process	2.037545e-2
GO:0060311	negative regulation of elastin catabolic process	2.063284e-2
GO:0060313	negative regulation of blood vessel remodeling	2.063284e-2
GO:0000917	barrier septum formation	2.063284e-2
GO:0010711	negative regulation of collagen catabolic process	2.063284e-2
GO:0010703	negative regulation of histolysis	2.063284e-2
GO:0002071	glandular epithelial cell maturation	2.063284e-2
GO:0051898	negative regulation of protein kinase B signaling cascade	2.084663e-2
GO:0007020	microtubule nucleation	2.085276e-2
GO:0042088	T-helper 1 type immune response	2.091743e-2
GO:0021603	cranial nerve formation	2.095393e-2
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	2.096858e-2
GO:0007023	post-chaperonin tubulin folding pathway	2.130110e-2
GO:0019230	proprioception	2.187838e-2
GO:0022011	myelination in peripheral nervous system	2.192152e-2
GO:0010424	DNA methylation on cytosine within a CG sequence	2.194745e-2
GO:0017187	peptidyl-glutamic acid carboxylation	2.202587e-2
GO:0048554	positive regulation of metalloenzyme activity	2.211589e-2
GO:0060450	positive regulation of hindgut contraction	2.212339e-2
GO:0021933	radial glia guided migration of cerebellar granule cell	2.212339e-2
GO:0051793	medium-chain fatty acid catabolic process	2.212339e-2
GO:0045925	positive regulation of female receptivity	2.212339e-2
GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA	2.212339e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016926	protein desumoylation	2.496775e-9
GO:0006297	nucleotide-excision repair, DNA gap filling	1.403076e-8
GO:0002536	respiratory burst involved in inflammatory response	1.200637e-7
GO:0014056	regulation of acetylcholine secretion	3.365286e-7
GO:0018023	peptidyl-lysine trimethylation	3.988142e-7
GO:0018364	peptidyl-glutamine methylation	4.404722e-7
GO:0018192	enzyme active site formation via L-cysteine persulfide	5.818532e-7
GO:0060136	embryonic process involved in female pregnancy	7.867469e-7
GO:0014051	gamma-aminobutyric acid secretion	1.009300e-6
GO:0043587	tongue morphogenesis	1.269432e-6
GO:0046605	regulation of centrosome cycle	3.352723e-6
GO:0006344	maintenance of chromatin silencing	3.665346e-6
GO:0006287	base-excision repair, gap-filling	6.925983e-6
GO:0007183	SMAD protein complex assembly	7.520407e-6
GO:0090084	negative regulation of inclusion body assembly	1.048965e-5
GO:0034502	protein localization to chromosome	1.185881e-5
GO:0046599	regulation of centriole replication	1.364852e-5
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.509429e-5
GO:0021528	commissural neuron differentiation in spinal cord	1.778636e-5
GO:0051103	DNA ligation involved in DNA repair	1.798064e-5
GO:0019348	dolichol metabolic process	1.999066e-5
GO:0051586	positive regulation of dopamine uptake	2.186377e-5
GO:0060390	regulation of SMAD protein import into nucleus	3.608851e-5
GO:0015812	gamma-aminobutyric acid transport	4.038962e-5
GO:0035990	tendon cell differentiation	4.127724e-5
GO:0035621	ER to Golgi ceramide transport	4.815421e-5
GO:0034227	tRNA thio-modification	5.599077e-5
GO:0033088	negative regulation of immature T cell proliferation in thymus	5.599077e-5
GO:0060391	positive regulation of SMAD protein import into nucleus	5.735906e-5
GO:0007288	sperm axoneme assembly	6.661018e-5
GO:0003130	BMP signaling pathway involved in heart induction	7.309809e-5
GO:0000910	cytokinesis	7.644113e-5
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	7.790187e-5
GO:0072198	mesenchymal cell proliferation involved in ureter development	7.790187e-5
GO:0072192	ureter epithelial cell differentiation	7.790187e-5
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	7.790187e-5
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	7.790187e-5
GO:0090194	negative regulation of glomerulus development	7.790187e-5
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	7.790187e-5
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	7.790187e-5
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	7.790187e-5
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	7.790187e-5
GO:0007500	mesodermal cell fate determination	7.790187e-5
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	7.790187e-5
GO:0055020	positive regulation of cardiac muscle fiber development	7.790187e-5
GO:0048392	intermediate mesodermal cell differentiation	7.790187e-5
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	7.790187e-5
GO:0060503	bud dilation involved in lung branching	7.790187e-5
GO:0071893	BMP signaling pathway involved in nephric duct formation	7.790187e-5
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	7.790187e-5
GO:0061155	pulmonary artery endothelial tube morphogenesis	7.790187e-5
GO:0061151	BMP signaling pathway involved in renal system segmentation	7.790187e-5
GO:0018243	protein O-linked glycosylation via threonine	7.828942e-5
GO:0018242	protein O-linked glycosylation via serine	7.828942e-5
GO:0021569	rhombomere 3 development	8.671619e-5
GO:0007214	gamma-aminobutyric acid signaling pathway	8.883056e-5
GO:0035993	deltoid tuberosity development	8.906479e-5
GO:0046785	microtubule polymerization	1.022625e-4
GO:0071169	establishment of protein localization to chromatin	1.072653e-4
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.072653e-4
GO:0016142	O-glycoside catabolic process	1.101001e-4
GO:0002098	tRNA wobble uridine modification	1.117411e-4
GO:0001829	trophectodermal cell differentiation	1.331985e-4
GO:0046952	ketone body catabolic process	1.468622e-4
GO:0009817	defense response to fungus, incompatible interaction	1.468622e-4
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	1.589148e-4
GO:0051881	regulation of mitochondrial membrane potential	1.601514e-4
GO:0006493	protein O-linked glycosylation	1.762077e-4
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.921655e-4
GO:0072205	metanephric collecting duct development	1.973415e-4
GO:0009798	axis specification	1.997118e-4
GO:0090169	regulation of spindle assembly	2.045244e-4
GO:0090234	regulation of kinetochore assembly	2.045244e-4
GO:0048671	negative regulation of collateral sprouting	2.165705e-4
GO:0032060	bleb assembly	2.165705e-4
GO:0009992	cellular water homeostasis	2.397126e-4
GO:0032446	protein modification by small protein conjugation	2.399333e-4
GO:0016567	protein ubiquitination	2.422380e-4
GO:0021578	hindbrain maturation	2.675007e-4
GO:0006266	DNA ligation	2.750419e-4
GO:0032287	peripheral nervous system myelin maintenance	2.844724e-4
GO:0046853	inositol or phosphatidylinositol phosphorylation	2.874207e-4
GO:0010452	histone H3-K36 methylation	2.926717e-4
GO:0021750	vestibular nucleus development	3.108425e-4
GO:0021679	cerebellar molecular layer development	3.108425e-4
GO:0010936	negative regulation of macrophage cytokine production	3.108425e-4
GO:0021590	cerebellum maturation	3.108425e-4
GO:0019673	GDP-mannose metabolic process	3.108425e-4
GO:0060674	placenta blood vessel development	3.172672e-4
GO:0050765	negative regulation of phagocytosis	3.397426e-4
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	3.544698e-4
GO:0021696	cerebellar cortex morphogenesis	3.637960e-4
GO:0032782	bile acid secretion	3.698505e-4
GO:0072355	histone H3-T3 phosphorylation	3.698505e-4
GO:0003096	renal sodium ion transport	3.698505e-4
GO:0001579	medium-chain fatty acid transport	3.698505e-4
GO:0060024	rhythmic synaptic transmission	3.953387e-4
GO:0030501	positive regulation of bone mineralization	4.043444e-4
GO:0003254	regulation of membrane depolarization	4.620821e-4
GO:0048670	regulation of collateral sprouting	4.649032e-4
GO:0071922	regulation of cohesin localization to chromatin	5.130838e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	5.130838e-4
GO:0016068	type I hypersensitivity	5.167744e-4
GO:2000772	regulation of cellular senescence	5.191010e-4
GO:0035269	protein O-linked mannosylation	5.231294e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	5.255197e-4
GO:0045226	extracellular polysaccharide biosynthetic process	5.529282e-4
GO:0042921	glucocorticoid receptor signaling pathway	5.637931e-4
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	5.645784e-4
GO:0046604	positive regulation of mitotic centrosome separation	5.716688e-4
GO:0070169	positive regulation of biomineral tissue development	5.863945e-4
GO:0021587	cerebellum morphogenesis	6.673066e-4
GO:0042136	neurotransmitter biosynthetic process	6.729233e-4
GO:0045662	negative regulation of myoblast differentiation	6.749006e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	6.815049e-4
GO:0071174	mitotic cell cycle spindle checkpoint	6.905274e-4
GO:0071168	protein localization to chromatin	7.436829e-4
GO:0002832	negative regulation of response to biotic stimulus	7.439369e-4
GO:0051148	negative regulation of muscle cell differentiation	7.806794e-4
GO:0021707	cerebellar granule cell differentiation	7.831875e-4
GO:0006268	DNA unwinding involved in replication	7.831875e-4
GO:0006284	base-excision repair	7.840796e-4
GO:0060439	trachea morphogenesis	8.333169e-4
GO:0021506	anterior neuropore closure	8.656674e-4
GO:0050883	musculoskeletal movement, spinal reflex action	8.918074e-4
GO:0035229	positive regulation of glutamate-cysteine ligase activity	8.964396e-4
GO:0021603	cranial nerve formation	9.208236e-4
GO:0071247	cellular response to chromate	9.569613e-4
GO:0032353	negative regulation of hormone biosynthetic process	9.723763e-4
GO:0050668	positive regulation of homocysteine metabolic process	1.017004e-3
GO:0045963	negative regulation of dopamine metabolic process	1.017004e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	1.037497e-3
GO:0070078	histone H3-R2 demethylation	1.066863e-3
GO:0070079	histone H4-R3 demethylation	1.066863e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.066863e-3
GO:0006713	glucocorticoid catabolic process	1.066863e-3
GO:0070286	axonemal dynein complex assembly	1.083211e-3
GO:0061154	endothelial tube morphogenesis	1.083211e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.083211e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1.083211e-3
GO:0010824	regulation of centrosome duplication	1.086241e-3
GO:0021610	facial nerve morphogenesis	1.156611e-3
GO:0055025	positive regulation of cardiac muscle tissue development	1.173729e-3
GO:0042660	positive regulation of cell fate specification	1.185247e-3
GO:0042053	regulation of dopamine metabolic process	1.185265e-3
GO:0021612	facial nerve structural organization	1.223048e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	1.224326e-3
GO:0010159	specification of organ position	1.224326e-3
GO:0014047	glutamate secretion	1.224326e-3
GO:2000425	regulation of apoptotic cell clearance	1.229106e-3
GO:0070647	protein modification by small protein conjugation or removal	1.236370e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	1.239019e-3
GO:0031958	corticosteroid receptor signaling pathway	1.292275e-3
GO:0021548	pons development	1.399435e-3
GO:0051900	regulation of mitochondrial depolarization	1.433139e-3
GO:0090086	negative regulation of protein deubiquitination	1.459856e-3
GO:0006474	N-terminal protein amino acid acetylation	1.475774e-3
GO:0018210	peptidyl-threonine modification	1.500264e-3
GO:0071459	protein localization to chromosome, centromeric region	1.541874e-3
GO:0051301	cell division	1.697257e-3
GO:0034587	piRNA metabolic process	1.712841e-3
GO:0016140	O-glycoside metabolic process	1.732678e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.746587e-3
GO:0010735	positive regulation of transcription via serum response element binding	1.795096e-3
GO:0031848	protection from non-homologous end joining at telomere	1.795096e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.845805e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.901912e-3
GO:0035441	cell migration involved in vasculogenesis	2.019887e-3
GO:0060433	bronchus development	2.030852e-3
GO:0070179	D-serine biosynthetic process	2.064561e-3
GO:0031584	activation of phospholipase D activity	2.149104e-3
GO:0010870	positive regulation of receptor biosynthetic process	2.149555e-3
GO:0032967	positive regulation of collagen biosynthetic process	2.239124e-3
GO:0021683	cerebellar granular layer morphogenesis	2.275280e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.275831e-3
GO:0009880	embryonic pattern specification	2.330582e-3
GO:0021697	cerebellar cortex formation	2.384298e-3
GO:0001975	response to amphetamine	2.391618e-3
GO:0043932	ossification involved in bone remodeling	2.635156e-3
GO:0032486	Rap protein signal transduction	2.648273e-3
GO:0042254	ribosome biogenesis	2.668279e-3
GO:0046836	glycolipid transport	2.834104e-3
GO:0060286	flagellar cell motility	2.834104e-3
GO:0008298	intracellular mRNA localization	2.834104e-3
GO:0002003	angiotensin maturation	2.834104e-3
GO:0061156	pulmonary artery morphogenesis	2.883313e-3
GO:0045116	protein neddylation	2.883313e-3
GO:0060440	trachea formation	2.911060e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	2.911060e-3
GO:0051590	positive regulation of neurotransmitter transport	2.911060e-3
GO:0035425	autocrine signaling	2.938284e-3
GO:0021658	rhombomere 3 morphogenesis	2.938284e-3
GO:0048672	positive regulation of collateral sprouting	2.942562e-3
GO:0045221	negative regulation of FasL biosynthetic process	2.967124e-3
GO:0045362	positive regulation of interleukin-1 biosynthetic process	2.967124e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.967124e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.967124e-3
GO:0042450	arginine biosynthetic process via ornithine	2.967124e-3
GO:0048239	negative regulation of DNA recombination at telomere	2.967124e-3
GO:0002731	negative regulation of dendritic cell cytokine production	2.967124e-3
GO:0032707	negative regulation of interleukin-23 production	2.967124e-3
GO:0006430	lysyl-tRNA aminoacylation	2.967124e-3
GO:0030150	protein import into mitochondrial matrix	2.967124e-3
GO:0019676	ammonia assimilation cycle	2.967124e-3
GO:0070585	protein localization in mitochondrion	3.007605e-3
GO:0033692	cellular polysaccharide biosynthetic process	3.078047e-3
GO:0070936	protein K48-linked ubiquitination	3.155966e-3
GO:0051168	nuclear export	3.165462e-3
GO:0048532	anatomical structure arrangement	3.368456e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	3.416110e-3
GO:0008208	C21-steroid hormone catabolic process	3.425705e-3
GO:0042069	regulation of catecholamine metabolic process	3.495783e-3
GO:0003161	cardiac conduction system development	3.584263e-3
GO:0021561	facial nerve development	3.592963e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	3.615523e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	3.735910e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	3.762140e-3
GO:0007422	peripheral nervous system development	3.812735e-3
GO:0007099	centriole replication	3.894024e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	3.921905e-3
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	3.921905e-3
GO:2000426	negative regulation of apoptotic cell clearance	3.946602e-3
GO:0019049	evasion of host defenses by virus	3.946602e-3
GO:0070366	regulation of hepatocyte differentiation	3.946602e-3
GO:0021575	hindbrain morphogenesis	3.953309e-3
GO:0060821	inactivation of X chromosome by DNA methylation	4.004056e-3
GO:0006780	uroporphyrinogen III biosynthetic process	4.004056e-3
GO:0071173	spindle assembly checkpoint	4.022682e-3
GO:0060384	innervation	4.118493e-3
GO:0035849	nephric duct elongation	4.218236e-3
GO:0035846	oviduct epithelium development	4.218236e-3
GO:0035847	uterine epithelium development	4.218236e-3
GO:0070370	cellular heat acclimation	4.218236e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	4.218236e-3
GO:0042335	cuticle development	4.218236e-3
GO:0035852	horizontal cell localization	4.218236e-3
GO:0032077	positive regulation of deoxyribonuclease activity	4.218236e-3
GO:0008052	sensory organ boundary specification	4.218236e-3
GO:0007402	ganglion mother cell fate determination	4.218236e-3
GO:0015853	adenine transport	4.218236e-3
GO:0015854	guanine transport	4.218236e-3
GO:0035356	cellular triglyceride homeostasis	4.218236e-3
GO:0035344	hypoxanthine transport	4.218236e-3
GO:0035364	thymine transport	4.218236e-3
GO:0021695	cerebellar cortex development	4.401997e-3
GO:0001710	mesodermal cell fate commitment	4.577071e-3
GO:0060177	regulation of angiotensin metabolic process	4.782707e-3
GO:0030219	megakaryocyte differentiation	4.945738e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	5.214774e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	5.214774e-3
GO:0021785	branchiomotor neuron axon guidance	5.238608e-3
GO:0032965	regulation of collagen biosynthetic process	5.294212e-3
GO:0060920	pacemaker cell differentiation	5.354530e-3
GO:0030038	contractile actin filament bundle assembly	5.533319e-3
GO:0035912	dorsal aorta morphogenesis	5.533319e-3
GO:0006611	protein export from nucleus	5.621626e-3
GO:0061004	pattern specification involved in kidney development	5.643704e-3
GO:0033083	regulation of immature T cell proliferation	5.673519e-3
GO:0021546	rhombomere development	5.673519e-3
GO:0009996	negative regulation of cell fate specification	5.673519e-3
GO:0046039	GTP metabolic process	5.803883e-3
GO:0018279	protein N-linked glycosylation via asparagine	6.308182e-3
GO:0022037	metencephalon development	6.351575e-3
GO:0048640	negative regulation of developmental growth	6.395435e-3
GO:0090083	regulation of inclusion body assembly	6.423194e-3
GO:0055119	relaxation of cardiac muscle	6.446204e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	6.511057e-3
GO:0048255	mRNA stabilization	6.528082e-3
GO:0035082	axoneme assembly	6.702487e-3
GO:0000917	barrier septum formation	6.776947e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	6.776947e-3
GO:0022417	protein maturation by protein folding	6.776947e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	6.786650e-3
GO:0002002	regulation of angiotensin levels in blood	6.786650e-3
GO:0000089	mitotic metaphase	6.995492e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	7.034711e-3
GO:0042363	fat-soluble vitamin catabolic process	7.034711e-3
GO:0033108	mitochondrial respiratory chain complex assembly	7.130055e-3
GO:0051176	positive regulation of sulfur metabolic process	7.131974e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	7.131974e-3
GO:0048389	intermediate mesoderm development	7.131974e-3
GO:0042256	mature ribosome assembly	7.131974e-3
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	7.132950e-3
GO:0033085	negative regulation of T cell differentiation in thymus	7.256751e-3
GO:0021978	telencephalon regionalization	7.351491e-3
GO:0072655	establishment of protein localization in mitochondrion	7.596737e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	7.758035e-3
GO:0065002	intracellular protein transmembrane transport	7.758035e-3
GO:0034970	histone H3-R2 methylation	7.758035e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	7.758035e-3
GO:0032065	cortical protein anchoring	7.758035e-3
GO:0003210	cardiac atrium formation	7.758035e-3
GO:0003236	sinus venosus morphogenesis	7.758035e-3
GO:0003259	cardioblast anterior-lateral migration	7.758035e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	7.764942e-3
GO:0003350	pulmonary myocardium development	7.764942e-3
GO:0070170	regulation of tooth mineralization	7.764942e-3
GO:0006184	GTP catabolic process	7.803066e-3
GO:0034259	negative regulation of Rho GTPase activity	7.812925e-3
GO:0070625	zymogen granule exocytosis	7.812925e-3
GO:0044314	protein K27-linked ubiquitination	7.812925e-3
GO:0000059	protein import into nucleus, docking	7.812925e-3
GO:0014057	positive regulation of acetylcholine secretion	7.812925e-3
GO:0072193	ureter smooth muscle cell differentiation	7.846101e-3
GO:0016584	nucleosome positioning	7.846101e-3
GO:0006397	mRNA processing	7.883731e-3
GO:0061034	olfactory bulb mitral cell layer development	8.161671e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	8.231679e-3
GO:0021871	forebrain regionalization	8.252713e-3
GO:0008380	RNA splicing	8.331168e-3
GO:0021570	rhombomere 4 development	8.478556e-3
GO:0000096	sulfur amino acid metabolic process	8.581832e-3
GO:0071470	cellular response to osmotic stress	8.604538e-3
GO:0021527	spinal cord association neuron differentiation	8.990563e-3
GO:0021884	forebrain neuron development	9.123042e-3
GO:0006383	transcription from RNA polymerase III promoter	9.180459e-3
GO:0021604	cranial nerve structural organization	9.217835e-3
GO:0090231	regulation of spindle checkpoint	9.261846e-3
GO:0006540	glutamate decarboxylation to succinate	9.334541e-3
GO:0018022	peptidyl-lysine methylation	9.383563e-3
GO:0006396	RNA processing	9.445530e-3
GO:0015937	coenzyme A biosynthetic process	9.833799e-3
GO:0007064	mitotic sister chromatid cohesion	9.861670e-3
GO:0000271	polysaccharide biosynthetic process	1.020559e-2
GO:0061198	fungiform papilla formation	1.021649e-2
GO:0061312	BMP signaling pathway involved in heart development	1.021649e-2
GO:0045819	positive regulation of glycogen catabolic process	1.021649e-2
GO:0060449	bud elongation involved in lung branching	1.049255e-2
GO:0060716	labyrinthine layer blood vessel development	1.058484e-2
GO:0034551	mitochondrial respiratory chain complex III assembly	1.088063e-2
GO:0060376	positive regulation of mast cell differentiation	1.088063e-2
GO:0010845	positive regulation of reciprocal meiotic recombination	1.088063e-2
GO:0003127	detection of nodal flow	1.088063e-2
GO:0072197	ureter morphogenesis	1.098083e-2
GO:0046847	filopodium assembly	1.113571e-2
GO:0060711	labyrinthine layer development	1.121633e-2
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1.144203e-2
GO:0034968	histone lysine methylation	1.152708e-2
GO:0031577	spindle checkpoint	1.155932e-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.225563e-2
GO:0030035	microspike assembly	1.233778e-2
GO:0014037	Schwann cell differentiation	1.237673e-2
GO:0046502	uroporphyrinogen III metabolic process	1.242967e-2
GO:0061360	optic chiasma development	1.242967e-2
GO:0035799	ureter maturation	1.242967e-2
GO:2000597	positive regulation of optic nerve formation	1.242967e-2
GO:0021633	optic nerve structural organization	1.242967e-2
GO:0007144	female meiosis I	1.242967e-2
GO:0021650	vestibulocochlear nerve formation	1.242967e-2
GO:0035562	negative regulation of chromatin binding	1.242967e-2
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	1.245564e-2
GO:0009994	oocyte differentiation	1.248980e-2
GO:0072300	positive regulation of metanephric glomerulus development	1.265232e-2
GO:0061196	fungiform papilla development	1.265232e-2
GO:0032929	negative regulation of superoxide anion generation	1.290207e-2
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.299191e-2
GO:0031365	N-terminal protein amino acid modification	1.302279e-2
GO:0071636	positive regulation of transforming growth factor beta production	1.349419e-2
GO:0033084	regulation of immature T cell proliferation in thymus	1.351679e-2
GO:0048561	establishment of organ orientation	1.356129e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.356129e-2
GO:0071104	response to interleukin-9	1.356129e-2
GO:0042664	negative regulation of endodermal cell fate specification	1.356129e-2
GO:0008295	spermidine biosynthetic process	1.356129e-2
GO:0009088	threonine biosynthetic process	1.356129e-2
GO:0021764	amygdala development	1.356129e-2
GO:0040040	thermosensory behavior	1.356129e-2
GO:0070672	response to interleukin-15	1.366932e-2
GO:0048143	astrocyte activation	1.379840e-2
GO:0006370	mRNA capping	1.379840e-2
GO:0010891	negative regulation of sequestering of triglyceride	1.398676e-2
GO:0003218	cardiac left ventricle formation	1.404911e-2
GO:0048599	oocyte development	1.417384e-2
GO:0000209	protein polyubiquitination	1.437545e-2
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.454235e-2
GO:0007041	lysosomal transport	1.470897e-2
GO:0060125	negative regulation of growth hormone secretion	1.482843e-2
GO:0051463	negative regulation of cortisol secretion	1.482843e-2
GO:0007057	spindle assembly involved in female meiosis I	1.482843e-2
GO:0021920	regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification	1.482843e-2
GO:0035502	metanephric ureteric bud development	1.482843e-2
GO:0034660	ncRNA metabolic process	1.490574e-2
GO:2000171	negative regulation of dendrite development	1.494559e-2
GO:0051204	protein insertion into mitochondrial membrane	1.494559e-2
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.494559e-2
GO:0060914	heart formation	1.500168e-2
GO:0060921	sinoatrial node cell differentiation	1.523232e-2
GO:0030031	cell projection assembly	1.538793e-2
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.551165e-2
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	1.551165e-2
GO:0048665	neuron fate specification	1.564673e-2
GO:0034241	positive regulation of macrophage fusion	1.579185e-2
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.579185e-2
GO:0035750	protein localization to myelin sheath abaxonal region	1.579185e-2
GO:0019047	provirus integration	1.579185e-2
GO:0006409	tRNA export from nucleus	1.579185e-2
GO:0006666	3-keto-sphinganine metabolic process	1.579185e-2
GO:0010983	positive regulation of high-density lipoprotein particle clearance	1.579185e-2
GO:0043524	negative regulation of neuron apoptosis	1.590141e-2
GO:0090192	regulation of glomerulus development	1.614778e-2
GO:0006364	rRNA processing	1.616534e-2
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	1.647182e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.647182e-2
GO:0010172	embryonic body morphogenesis	1.654916e-2
GO:0072044	collecting duct development	1.671940e-2
GO:0042133	neurotransmitter metabolic process	1.681725e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.683454e-2
GO:0016572	histone phosphorylation	1.683454e-2
GO:2001037	positive regulation of tongue muscle cell differentiation	1.695919e-2
GO:0034653	retinoic acid catabolic process	1.695919e-2
GO:0006465	signal peptide processing	1.703237e-2
GO:0010498	proteasomal protein catabolic process	1.707747e-2
GO:0003181	atrioventricular valve morphogenesis	1.710683e-2
GO:0035117	embryonic arm morphogenesis	1.710759e-2
GO:0034441	plasma lipoprotein particle oxidation	1.755728e-2
GO:0046501	protoporphyrinogen IX metabolic process	1.755728e-2
GO:0019388	galactose catabolic process	1.755728e-2
GO:0001893	maternal placenta development	1.757039e-2
GO:0042490	mechanoreceptor differentiation	1.773252e-2
GO:0035567	non-canonical Wnt receptor signaling pathway	1.814092e-2
GO:0072015	glomerular visceral epithelial cell development	1.814793e-2
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.814793e-2
GO:0048793	pronephros development	1.820800e-2
GO:0051028	mRNA transport	1.867895e-2
GO:0090303	positive regulation of wound healing	1.868511e-2
GO:0021571	rhombomere 5 development	1.868511e-2
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	1.868511e-2
GO:0016072	rRNA metabolic process	1.871248e-2
GO:0045906	negative regulation of vasoconstriction	1.883715e-2
GO:0006538	glutamate catabolic process	1.883715e-2
GO:0032508	DNA duplex unwinding	1.890041e-2
GO:0072498	embryonic skeletal joint development	1.922467e-2
GO:2000142	regulation of transcription initiation, DNA-dependent	1.952186e-2
GO:0008333	endosome to lysosome transport	1.962314e-2
GO:0090224	regulation of spindle organization	2.029276e-2
GO:0038007	netrin-activated signaling pathway	2.031776e-2
GO:0034214	protein hexamerization	2.031776e-2
GO:0051013	microtubule severing	2.031776e-2
GO:0021623	oculomotor nerve formation	2.031776e-2
GO:0003404	optic vesicle morphogenesis	2.031776e-2
GO:0003409	optic cup structural organization	2.031776e-2
GO:0043217	myelin maintenance	2.051665e-2
GO:0006511	ubiquitin-dependent protein catabolic process	2.057674e-2
GO:0045778	positive regulation of ossification	2.081697e-2
GO:0070734	histone H3-K27 methylation	2.088220e-2
GO:0006288	base-excision repair, DNA ligation	2.088220e-2
GO:0051084	'de novo' posttranslational protein folding	2.089156e-2
GO:0048701	embryonic cranial skeleton morphogenesis	2.094300e-2
GO:0060113	inner ear receptor cell differentiation	2.111250e-2
GO:0070244	negative regulation of thymocyte apoptosis	2.147017e-2
GO:0010454	negative regulation of cell fate commitment	2.155059e-2
GO:0001834	trophectodermal cell proliferation	2.159411e-2
GO:0045064	T-helper 2 cell differentiation	2.159411e-2
GO:0002719	negative regulation of cytokine production involved in immune response	2.172114e-2
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	2.174173e-2
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	2.185018e-2
GO:0021562	vestibulocochlear nerve development	2.187280e-2
GO:0018126	protein hydroxylation	2.187280e-2
GO:0051329	interphase of mitotic cell cycle	2.197822e-2
GO:0051901	positive regulation of mitochondrial depolarization	2.240546e-2
GO:0021549	cerebellum development	2.262851e-2
GO:0009082	branched chain family amino acid biosynthetic process	2.267109e-2
GO:0030521	androgen receptor signaling pathway	2.270080e-2
GO:0051351	positive regulation of ligase activity	2.301384e-2
GO:0051926	negative regulation of calcium ion transport	2.301384e-2
GO:0060066	oviduct development	2.307473e-2
GO:0003406	retinal pigment epithelium development	2.319023e-2
GO:0000414	regulation of histone H3-K36 methylation	2.319023e-2
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	2.319023e-2
GO:0019941	modification-dependent protein catabolic process	2.360846e-2
GO:0034635	glutathione transport	2.376416e-2
GO:0003278	apoptosis involved in heart morphogenesis	2.376416e-2
GO:0032074	negative regulation of nuclease activity	2.376416e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	2.398858e-2
GO:0006434	seryl-tRNA aminoacylation	2.398858e-2
GO:0006420	arginyl-tRNA aminoacylation	2.398858e-2
GO:0006424	glutamyl-tRNA aminoacylation	2.398858e-2
GO:0003015	heart process	2.400343e-2
GO:0090193	positive regulation of glomerulus development	2.410395e-2
GO:0016188	synaptic vesicle maturation	2.410395e-2
GO:0060789	hair follicle placode formation	2.410395e-2
GO:0030433	ER-associated protein catabolic process	2.425316e-2
GO:0044253	positive regulation of multicellular organismal metabolic process	2.431046e-2
GO:0021681	cerebellar granular layer development	2.447816e-2
GO:0032392	DNA geometric change	2.447816e-2
GO:0045839	negative regulation of mitosis	2.448372e-2
GO:0060272	embryonic skeletal joint morphogenesis	2.452946e-2
GO:0043064	flagellum organization	2.452946e-2
GO:0051325	interphase	2.477682e-2
GO:0000045	autophagic vacuole assembly	2.511775e-2
GO:0072095	regulation of branch elongation involved in ureteric bud branching	2.523072e-2
GO:2000649	regulation of sodium ion transmembrane transporter activity	2.529560e-2
GO:0010561	negative regulation of glycoprotein biosynthetic process	2.529560e-2
GO:0071281	cellular response to iron ion	2.538017e-2
GO:0090187	positive regulation of pancreatic juice secretion	2.610798e-2
GO:0090340	positive regulation of secretion of lysosomal enzymes	2.610798e-2
GO:0051545	negative regulation of elastin biosynthetic process	2.610798e-2
GO:0090108	positive regulation of high-density lipoprotein particle assembly	2.610798e-2
GO:0006653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	2.610798e-2
GO:0060026	convergent extension	2.615563e-2