Novel motif:142

name:	motif142_TCATATAGAGAAGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0051915	induction of synaptic plasticity by chemical substance	2.357516e-16
GO:0047497	mitochondrion transport along microtubule	4.332547e-16
GO:0051654	establishment of mitochondrion localization	1.327902e-14
GO:0048676	axon extension involved in development	1.557069e-14
GO:0014823	response to activity	1.898118e-13
GO:0010661	positive regulation of muscle cell apoptosis	2.000218e-13
GO:0014012	peripheral nervous system axon regeneration	3.643418e-13
GO:0048678	response to axon injury	4.492348e-13
GO:0048066	developmental pigmentation	5.687147e-12
GO:0010666	positive regulation of cardiac muscle cell apoptosis	6.625289e-12
GO:0051646	mitochondrion localization	6.648055e-12
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.442231e-11
GO:0033591	response to L-ascorbic acid	1.773466e-11
GO:0022407	regulation of cell-cell adhesion	2.001326e-11
GO:0061162	establishment of monopolar cell polarity	2.111758e-11
GO:0007026	negative regulation of microtubule depolymerization	3.103700e-11
GO:0031331	positive regulation of cellular catabolic process	3.306808e-11
GO:0031114	regulation of microtubule depolymerization	5.344692e-11
GO:0022409	positive regulation of cell-cell adhesion	1.121112e-10
GO:0001306	age-dependent response to oxidative stress	1.495348e-10
GO:0031103	axon regeneration	1.536547e-10
GO:0051094	positive regulation of developmental process	2.810156e-10
GO:0050931	pigment cell differentiation	3.532889e-10
GO:0070253	somatostatin secretion	4.117381e-10
GO:0032812	positive regulation of epinephrine secretion	4.117381e-10
GO:0031915	positive regulation of synaptic plasticity	4.138371e-10
GO:0010970	microtubule-based transport	6.117696e-10
GO:0030307	positive regulation of cell growth	6.149136e-10
GO:0032364	oxygen homeostasis	8.978708e-10
GO:0070997	neuron death	1.215386e-9
GO:0030162	regulation of proteolysis	1.269735e-9
GO:0006582	melanin metabolic process	1.319914e-9
GO:0042345	regulation of NF-kappaB import into nucleus	1.356426e-9
GO:0014912	negative regulation of smooth muscle cell migration	1.742746e-9
GO:0008089	anterograde axon cargo transport	2.802698e-9
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2.911735e-9
GO:0031116	positive regulation of microtubule polymerization	4.140294e-9
GO:0030705	cytoskeleton-dependent intracellular transport	4.692110e-9
GO:0060052	neurofilament cytoskeleton organization	5.577576e-9
GO:0048773	erythrophore differentiation	6.224560e-9
GO:0034021	response to silicon dioxide	6.224560e-9
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	6.224560e-9
GO:0001315	age-dependent response to reactive oxygen species	6.224560e-9
GO:0042346	positive regulation of NF-kappaB import into nucleus	8.795100e-9
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.025455e-8
GO:0045110	intermediate filament bundle assembly	1.027417e-8
GO:0043438	acetoacetic acid metabolic process	1.079410e-8
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	1.122940e-8
GO:0032722	positive regulation of chemokine production	1.184716e-8
GO:0007018	microtubule-based movement	1.822473e-8
GO:0072384	organelle transport along microtubule	1.946192e-8
GO:0033693	neurofilament bundle assembly	2.020448e-8
GO:0031112	positive regulation of microtubule polymerization or depolymerization	2.092188e-8
GO:0090287	regulation of cellular response to growth factor stimulus	2.187492e-8
GO:0042221	response to chemical stimulus	2.224225e-8
GO:0051881	regulation of mitochondrial membrane potential	2.301583e-8
GO:0008285	negative regulation of cell proliferation	2.681851e-8
GO:0001578	microtubule bundle formation	2.709722e-8
GO:0007154	cell communication	2.933782e-8
GO:0007568	aging	3.327445e-8
GO:0033483	gas homeostasis	3.464422e-8
GO:0043242	negative regulation of protein complex disassembly	3.464849e-8
GO:2000026	regulation of multicellular organismal development	3.474718e-8
GO:0045617	negative regulation of keratinocyte differentiation	3.693248e-8
GO:0050877	neurological system process	3.763374e-8
GO:0048522	positive regulation of cellular process	4.581820e-8
GO:0045595	regulation of cell differentiation	4.736740e-8
GO:0010665	regulation of cardiac muscle cell apoptosis	4.896314e-8
GO:0070507	regulation of microtubule cytoskeleton organization	5.219670e-8
GO:0014910	regulation of smooth muscle cell migration	5.329562e-8
GO:0019605	butyrate metabolic process	6.215266e-8
GO:0042127	regulation of cell proliferation	6.947710e-8
GO:0043473	pigmentation	7.771301e-8
GO:0019896	axon transport of mitochondrion	8.249839e-8
GO:0010660	regulation of muscle cell apoptosis	8.430719e-8
GO:0043244	regulation of protein complex disassembly	8.681209e-8
GO:0032642	regulation of chemokine production	1.052400e-7
GO:0046902	regulation of mitochondrial membrane permeability	1.216497e-7
GO:0031102	neuron projection regeneration	1.350006e-7
GO:0017085	response to insecticide	1.355353e-7
GO:0042427	serotonin biosynthetic process	1.388465e-7
GO:0048630	skeletal muscle tissue growth	1.531527e-7
GO:0045104	intermediate filament cytoskeleton organization	1.780535e-7
GO:0016358	dendrite development	1.878963e-7
GO:0031334	positive regulation of protein complex assembly	1.947269e-7
GO:0010662	regulation of striated muscle cell apoptosis	2.041260e-7
GO:0045861	negative regulation of proteolysis	2.089143e-7
GO:0009896	positive regulation of catabolic process	2.120849e-7
GO:0045605	negative regulation of epidermal cell differentiation	2.334358e-7
GO:0070093	negative regulation of glucagon secretion	2.384438e-7
GO:0010035	response to inorganic substance	2.429256e-7
GO:0010942	positive regulation of cell death	2.493432e-7
GO:0043068	positive regulation of programmed cell death	2.857664e-7
GO:0048589	developmental growth	3.295796e-7
GO:0031113	regulation of microtubule polymerization	3.439954e-7
GO:0070163	regulation of adiponectin secretion	3.979228e-7
GO:0045103	intermediate filament-based process	4.392675e-7
GO:0031110	regulation of microtubule polymerization or depolymerization	4.394655e-7
GO:0048675	axon extension	4.553100e-7
GO:0051402	neuron apoptosis	4.760101e-7
GO:0045862	positive regulation of proteolysis	4.942561e-7
GO:0032757	positive regulation of interleukin-8 production	5.379845e-7
GO:0009987	cellular process	5.670438e-7
GO:0010574	regulation of vascular endothelial growth factor production	6.024587e-7
GO:0046459	short-chain fatty acid metabolic process	6.739463e-7
GO:0051716	cellular response to stimulus	6.793692e-7
GO:0042438	melanin biosynthetic process	6.802823e-7
GO:2000172	regulation of branching morphogenesis of a nerve	7.078020e-7
GO:0070092	regulation of glucagon secretion	7.387666e-7
GO:0032886	regulation of microtubule-based process	7.621242e-7
GO:0045597	positive regulation of cell differentiation	7.662266e-7
GO:0032387	negative regulation of intracellular transport	7.977396e-7
GO:0019748	secondary metabolic process	8.160684e-7
GO:0010038	response to metal ion	8.711542e-7
GO:0050665	hydrogen peroxide biosynthetic process	8.902157e-7
GO:0023052	signaling	9.028456e-7
GO:0042493	response to drug	9.305738e-7
GO:0051149	positive regulation of muscle cell differentiation	9.750660e-7
GO:0043065	positive regulation of apoptosis	1.202336e-6
GO:0031099	regeneration	1.247777e-6
GO:0071456	cellular response to hypoxia	1.273042e-6
GO:0016310	phosphorylation	1.300438e-6
GO:0050670	regulation of lymphocyte proliferation	1.343281e-6
GO:0032386	regulation of intracellular transport	1.346672e-6
GO:0010575	positive regulation vascular endothelial growth factor production	1.399459e-6
GO:0032330	regulation of chondrocyte differentiation	1.399644e-6
GO:0010033	response to organic substance	1.440740e-6
GO:0045663	positive regulation of myoblast differentiation	1.453301e-6
GO:0002063	chondrocyte development	1.486617e-6
GO:0050793	regulation of developmental process	1.490300e-6
GO:0071361	cellular response to ethanol	1.579755e-6
GO:0070164	negative regulation of adiponectin secretion	1.754005e-6
GO:0060355	positive regulation of cell adhesion molecule production	1.754005e-6
GO:0035505	positive regulation of myosin light chain kinase activity	1.754005e-6
GO:0007166	cell surface receptor linked signaling pathway	1.818430e-6
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.959642e-6
GO:0032944	regulation of mononuclear cell proliferation	2.100077e-6
GO:0006468	protein phosphorylation	2.366238e-6
GO:0046627	negative regulation of insulin receptor signaling pathway	2.382720e-6
GO:0042993	positive regulation of transcription factor import into nucleus	2.392194e-6
GO:0043254	regulation of protein complex assembly	2.469994e-6
GO:0010647	positive regulation of cell communication	2.617339e-6
GO:0042990	regulation of transcription factor import into nucleus	2.669010e-6
GO:0006259	DNA metabolic process	2.933757e-6
GO:0009725	response to hormone stimulus	3.049008e-6
GO:0007252	I-kappaB phosphorylation	3.089892e-6
GO:0014041	regulation of neuron maturation	3.210757e-6
GO:0002062	chondrocyte differentiation	3.265460e-6
GO:0006996	organelle organization	3.417646e-6
GO:0035426	extracellular matrix-cell signaling	3.548113e-6
GO:0032273	positive regulation of protein polymerization	3.565108e-6
GO:0050772	positive regulation of axonogenesis	3.809096e-6
GO:0023056	positive regulation of signaling	3.843991e-6
GO:0042628	mating plug formation	3.952034e-6
GO:0061110	dense core granule biogenesis	3.952034e-6
GO:0090331	negative regulation of platelet aggregation	3.952034e-6
GO:0061108	seminal vesicle epithelium development	3.952034e-6
GO:0045683	negative regulation of epidermis development	4.297055e-6
GO:0020027	hemoglobin metabolic process	4.327462e-6
GO:0043434	response to peptide hormone stimulus	4.447389e-6
GO:0050896	response to stimulus	4.840163e-6
GO:0003032	detection of oxygen	4.905061e-6
GO:0002765	immune response-inhibiting signal transduction	5.082522e-6
GO:0009612	response to mechanical stimulus	5.162180e-6
GO:0048588	developmental cell growth	5.262231e-6
GO:0048743	positive regulation of skeletal muscle fiber development	5.269941e-6
GO:0001660	fever generation	5.553182e-6
GO:0034123	positive regulation of toll-like receptor signaling pathway	5.873177e-6
GO:0043497	regulation of protein heterodimerization activity	6.275789e-6
GO:0009124	nucleoside monophosphate biosynthetic process	6.313006e-6
GO:0048742	regulation of skeletal muscle fiber development	6.643738e-6
GO:0033129	positive regulation of histone phosphorylation	6.667270e-6
GO:0046219	indolalkylamine biosynthetic process	6.747161e-6
GO:0001808	negative regulation of type IV hypersensitivity	6.945628e-6
GO:0042440	pigment metabolic process	7.694615e-6
GO:0050808	synapse organization	8.281371e-6
GO:0042325	regulation of phosphorylation	8.432713e-6
GO:0048518	positive regulation of biological process	8.552692e-6
GO:0003085	negative regulation of systemic arterial blood pressure	8.804469e-6
GO:0051494	negative regulation of cytoskeleton organization	9.252784e-6
GO:0001807	regulation of type IV hypersensitivity	9.303417e-6
GO:0018107	peptidyl-threonine phosphorylation	9.729598e-6
GO:0045616	regulation of keratinocyte differentiation	9.792840e-6
GO:0048807	female genitalia morphogenesis	9.953122e-6
GO:0010941	regulation of cell death	9.992209e-6
GO:0001932	regulation of protein phosphorylation	1.012540e-5
GO:0007296	vitellogenesis	1.019282e-5
GO:0001836	release of cytochrome c from mitochondria	1.042407e-5
GO:0023051	regulation of signaling	1.047514e-5
GO:0042327	positive regulation of phosphorylation	1.077850e-5
GO:0007219	Notch signaling pathway	1.092458e-5
GO:0045354	regulation of interferon-alpha biosynthetic process	1.118524e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.229856e-5
GO:0040007	growth	1.232196e-5
GO:0007499	ectoderm and mesoderm interaction	1.311198e-5
GO:0043627	response to estrogen stimulus	1.369111e-5
GO:0009966	regulation of signal transduction	1.387284e-5
GO:0060284	regulation of cell development	1.422631e-5
GO:0035690	cellular response to drug	1.486721e-5
GO:0045773	positive regulation of axon extension	1.597621e-5
GO:0046626	regulation of insulin receptor signaling pathway	1.601490e-5
GO:0016202	regulation of striated muscle tissue development	1.619212e-5
GO:0009161	ribonucleoside monophosphate metabolic process	1.638399e-5
GO:0007267	cell-cell signaling	1.653478e-5
GO:0009719	response to endogenous stimulus	1.801974e-5
GO:0032755	positive regulation of interleukin-6 production	1.820379e-5
GO:0034111	negative regulation of homotypic cell-cell adhesion	1.870818e-5
GO:0048873	homeostasis of number of cells within a tissue	1.881140e-5
GO:0007165	signal transduction	1.961627e-5
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	2.025741e-5
GO:0032268	regulation of cellular protein metabolic process	2.032021e-5
GO:0007569	cell aging	2.048722e-5
GO:0043067	regulation of programmed cell death	2.060261e-5
GO:0040012	regulation of locomotion	2.067098e-5
GO:0002437	inflammatory response to antigenic stimulus	2.076245e-5
GO:0007292	female gamete generation	2.144369e-5
GO:0051130	positive regulation of cellular component organization	2.163017e-5
GO:0032270	positive regulation of cellular protein metabolic process	2.177629e-5
GO:0019220	regulation of phosphate metabolic process	2.186618e-5
GO:0044087	regulation of cellular component biogenesis	2.368589e-5
GO:0071453	cellular response to oxygen levels	2.384431e-5
GO:0033273	response to vitamin	2.440952e-5
GO:0048147	negative regulation of fibroblast proliferation	2.482012e-5
GO:0070059	apoptosis in response to endoplasmic reticulum stress	2.499784e-5
GO:0048505	regulation of timing of cell differentiation	2.516253e-5
GO:0006950	response to stress	2.518584e-5
GO:0010604	positive regulation of macromolecule metabolic process	2.572089e-5
GO:0018210	peptidyl-threonine modification	2.625034e-5
GO:0045937	positive regulation of phosphate metabolic process	2.641898e-5
GO:0014805	smooth muscle adaptation	2.663801e-5
GO:0032647	regulation of interferon-alpha production	2.663801e-5
GO:0048660	regulation of smooth muscle cell proliferation	2.668415e-5
GO:0042981	regulation of apoptosis	2.725391e-5
GO:0010226	response to lithium ion	2.760781e-5
GO:0070663	regulation of leukocyte proliferation	2.834462e-5
GO:0030318	melanocyte differentiation	2.873387e-5
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	3.153583e-5
GO:0006928	cellular component movement	3.172915e-5
GO:0045671	negative regulation of osteoclast differentiation	3.194242e-5
GO:0031401	positive regulation of protein modification process	3.271447e-5
GO:0030334	regulation of cell migration	3.328737e-5
GO:0051043	regulation of membrane protein ectodomain proteolysis	3.339225e-5
GO:0006089	lactate metabolic process	3.487972e-5
GO:0048662	negative regulation of smooth muscle cell proliferation	3.497512e-5
GO:0051239	regulation of multicellular organismal process	3.659806e-5
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	3.675409e-5
GO:0001816	cytokine production	3.721683e-5
GO:0009072	aromatic amino acid family metabolic process	3.762410e-5
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	3.775266e-5
GO:0015939	pantothenate metabolic process	3.775266e-5
GO:0048634	regulation of muscle organ development	3.788210e-5
GO:0090066	regulation of anatomical structure size	3.797503e-5
GO:0008088	axon cargo transport	3.832945e-5
GO:0010573	vascular endothelial growth factor production	3.870058e-5
GO:0001546	preantral ovarian follicle growth	3.905753e-5
GO:0006796	phosphate-containing compound metabolic process	4.069194e-5
GO:0032108	negative regulation of response to nutrient levels	4.136385e-5
GO:0034110	regulation of homotypic cell-cell adhesion	4.168014e-5
GO:0033127	regulation of histone phosphorylation	4.184310e-5
GO:2000173	negative regulation of branching morphogenesis of a nerve	4.237507e-5
GO:0033689	negative regulation of osteoblast proliferation	4.325766e-5
GO:0019430	removal of superoxide radicals	4.368514e-5
GO:0051541	elastin metabolic process	4.418195e-5
GO:0045080	positive regulation of chemokine biosynthetic process	4.579295e-5
GO:0010638	positive regulation of organelle organization	4.746492e-5
GO:0010907	positive regulation of glucose metabolic process	4.779608e-5
GO:0045355	negative regulation of interferon-alpha biosynthetic process	4.802108e-5
GO:0038003	opioid receptor signaling pathway	4.959115e-5
GO:0030889	negative regulation of B cell proliferation	5.082048e-5
GO:0010646	regulation of cell communication	5.106250e-5
GO:0046827	positive regulation of protein export from nucleus	5.135544e-5
GO:0051128	regulation of cellular component organization	5.295407e-5
GO:0009156	ribonucleoside monophosphate biosynthetic process	5.418195e-5
GO:0042554	superoxide anion generation	5.423300e-5
GO:0007005	mitochondrion organization	5.432055e-5
GO:0071248	cellular response to metal ion	5.462795e-5
GO:0008090	retrograde axon cargo transport	5.522022e-5
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.555358e-5
GO:0030730	sequestering of triglyceride	5.580170e-5
GO:0045927	positive regulation of growth	5.609807e-5
GO:0051640	organelle localization	5.671545e-5
GO:0032770	positive regulation of monooxygenase activity	5.672721e-5
GO:0042428	serotonin metabolic process	5.875856e-5
GO:0009888	tissue development	5.969186e-5
GO:0048753	pigment granule organization	5.970816e-5
GO:0033554	cellular response to stress	6.091590e-5
GO:0060197	cloacal septation	6.123436e-5
GO:0071841	cellular component organization or biogenesis at cellular level	6.364263e-5
GO:0044281	small molecule metabolic process	6.506024e-5
GO:0001934	positive regulation of protein phosphorylation	6.587256e-5
GO:0007416	synapse assembly	6.618515e-5
GO:0071223	cellular response to lipoteichoic acid	6.632686e-5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	6.710874e-5
GO:0045661	regulation of myoblast differentiation	6.724522e-5
GO:0051606	detection of stimulus	6.859815e-5
GO:0042129	regulation of T cell proliferation	6.936168e-5
GO:0071637	regulation of monocyte chemotactic protein-1 production	6.938872e-5
GO:0010975	regulation of neuron projection development	6.973052e-5
GO:0070887	cellular response to chemical stimulus	7.064608e-5
GO:0009595	detection of biotic stimulus	7.247714e-5
GO:0015887	pantothenate transmembrane transport	7.271066e-5
GO:0015878	biotin transport	7.271066e-5
GO:0010332	response to gamma radiation	7.497181e-5
GO:0009123	nucleoside monophosphate metabolic process	7.686005e-5
GO:0032872	regulation of stress-activated MAPK cascade	7.815624e-5
GO:0009967	positive regulation of signal transduction	7.847119e-5
GO:0045410	positive regulation of interleukin-6 biosynthetic process	7.893661e-5
GO:2000145	regulation of cell motility	7.922971e-5
GO:0010193	response to ozone	7.932111e-5
GO:0007610	behavior	7.969556e-5
GO:0019079	viral genome replication	8.158776e-5
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	8.255271e-5
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	8.255271e-5
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	8.255271e-5
GO:0045428	regulation of nitric oxide biosynthetic process	8.319728e-5
GO:0048583	regulation of response to stimulus	8.483989e-5
GO:0033043	regulation of organelle organization	8.887647e-5
GO:0031399	regulation of protein modification process	8.888776e-5
GO:0009893	positive regulation of metabolic process	8.992983e-5
GO:0007017	microtubule-based process	9.039783e-5
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	9.048998e-5
GO:0046822	regulation of nucleocytoplasmic transport	9.366354e-5
GO:0071842	cellular component organization at cellular level	9.607080e-5
GO:0006691	leukotriene metabolic process	9.805199e-5
GO:0001649	osteoblast differentiation	9.842892e-5
GO:0002904	positive regulation of B cell apoptosis	9.873670e-5
GO:0010564	regulation of cell cycle process	9.976735e-5
GO:0055072	iron ion homeostasis	1.029608e-4
GO:0032308	positive regulation of prostaglandin secretion	1.047537e-4
GO:0051051	negative regulation of transport	1.050419e-4
GO:0050996	positive regulation of lipid catabolic process	1.060473e-4
GO:0042176	regulation of protein catabolic process	1.091361e-4
GO:0031346	positive regulation of cell projection organization	1.107694e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.154225e-4
GO:0044060	regulation of endocrine process	1.159480e-4
GO:0006586	indolalkylamine metabolic process	1.159480e-4
GO:0051153	regulation of striated muscle cell differentiation	1.180778e-4
GO:0050671	positive regulation of lymphocyte proliferation	1.182462e-4
GO:0021542	dentate gyrus development	1.193089e-4
GO:0009593	detection of chemical stimulus	1.202395e-4
GO:0050865	regulation of cell activation	1.218135e-4
GO:0042306	regulation of protein import into nucleus	1.219887e-4
GO:0060485	mesenchyme development	1.247152e-4
GO:0060249	anatomical structure homeostasis	1.247152e-4
GO:0010676	positive regulation of cellular carbohydrate metabolic process	1.285679e-4
GO:0019068	virion assembly	1.299477e-4
GO:0031622	positive regulation of fever generation	1.319309e-4
GO:0031000	response to caffeine	1.319309e-4
GO:0051155	positive regulation of striated muscle cell differentiation	1.328108e-4
GO:0046686	response to cadmium ion	1.343051e-4
GO:0045604	regulation of epidermal cell differentiation	1.363894e-4
GO:0014050	negative regulation of glutamate secretion	1.379254e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.384586e-4
GO:0033059	cellular pigmentation	1.429357e-4
GO:0048312	intracellular distribution of mitochondria	1.449151e-4
GO:0065009	regulation of molecular function	1.466463e-4
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.484792e-4
GO:0007006	mitochondrial membrane organization	1.495567e-4
GO:0032760	positive regulation of tumor necrosis factor production	1.545643e-4
GO:0032271	regulation of protein polymerization	1.584456e-4
GO:0032677	regulation of interleukin-8 production	1.593958e-4
GO:0006916	anti-apoptosis	1.609267e-4
GO:0007417	central nervous system development	1.616671e-4
GO:0010269	response to selenium ion	1.659674e-4
GO:0007268	synaptic transmission	1.690677e-4
GO:0045598	regulation of fat cell differentiation	1.756868e-4
GO:0032501	multicellular organismal process	1.767241e-4
GO:0032946	positive regulation of mononuclear cell proliferation	1.791863e-4
GO:0000303	response to superoxide	1.803501e-4
GO:0009605	response to external stimulus	1.805805e-4
GO:0043393	regulation of protein binding	1.808813e-4
GO:0032481	positive regulation of type I interferon production	1.827998e-4
GO:0014033	neural crest cell differentiation	1.861988e-4
GO:0031652	positive regulation of heat generation	1.887182e-4
GO:0051960	regulation of nervous system development	1.925117e-4
GO:0043412	macromolecule modification	1.934563e-4
GO:0070050	neuron homeostasis	1.964231e-4
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.996265e-4
GO:0019067	viral assembly, maturation, egress, and release	2.012313e-4
GO:0010639	negative regulation of organelle organization	2.052751e-4
GO:0051182	coenzyme transport	2.107283e-4
GO:0045599	negative regulation of fat cell differentiation	2.108638e-4
GO:0032355	response to estradiol stimulus	2.154378e-4
GO:0000186	activation of MAPKK activity	2.177781e-4
GO:0071241	cellular response to inorganic substance	2.191390e-4
GO:0034599	cellular response to oxidative stress	2.192295e-4
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	2.192998e-4
GO:0001837	epithelial to mesenchymal transition	2.222660e-4
GO:0071392	cellular response to estradiol stimulus	2.232474e-4
GO:0072593	reactive oxygen species metabolic process	2.282123e-4
GO:0051965	positive regulation of synapse assembly	2.291695e-4
GO:0051098	regulation of binding	2.319089e-4
GO:0031344	regulation of cell projection organization	2.346190e-4
GO:0032880	regulation of protein localization	2.372700e-4
GO:0045747	positive regulation of Notch signaling pathway	2.409179e-4
GO:0032663	regulation of interleukin-2 production	2.435662e-4
GO:0044089	positive regulation of cellular component biogenesis	2.435796e-4
GO:0045880	positive regulation of smoothened signaling pathway	2.458676e-4
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.475523e-4
GO:0009949	polarity specification of anterior/posterior axis	2.475523e-4
GO:0032879	regulation of localization	2.484287e-4
GO:0014042	positive regulation of neuron maturation	2.503361e-4
GO:0032848	negative regulation of cellular pH reduction	2.503361e-4
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	2.503361e-4
GO:0021747	cochlear nucleus development	2.503361e-4
GO:0042100	B cell proliferation	2.537719e-4
GO:0010044	response to aluminum ion	2.561516e-4
GO:0001558	regulation of cell growth	2.567144e-4
GO:0006954	inflammatory response	2.583428e-4
GO:0045429	positive regulation of nitric oxide biosynthetic process	2.637901e-4
GO:0002694	regulation of leukocyte activation	2.652501e-4
GO:0010042	response to manganese ion	2.656417e-4
GO:0045648	positive regulation of erythrocyte differentiation	2.678507e-4
GO:0034644	cellular response to UV	2.680130e-4
GO:0051179	localization	2.704852e-4
GO:0048513	organ development	2.706290e-4
GO:0032874	positive regulation of stress-activated MAPK cascade	2.722090e-4
GO:0007028	cytoplasm organization	2.722901e-4
GO:0051656	establishment of organelle localization	2.739009e-4
GO:0035880	embryonic nail plate morphogenesis	2.756805e-4
GO:0061002	negative regulation of dendritic spine morphogenesis	2.760773e-4
GO:0014850	response to muscle activity	2.781616e-4
GO:0007600	sensory perception	2.783880e-4
GO:0009165	nucleotide biosynthetic process	2.788017e-4
GO:0050767	regulation of neurogenesis	2.803666e-4
GO:0048871	multicellular organismal homeostasis	2.915947e-4
GO:0060537	muscle tissue development	2.929475e-4
GO:0046688	response to copper ion	2.942589e-4
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	2.990271e-4
GO:0051249	regulation of lymphocyte activation	2.996981e-4
GO:0032728	positive regulation of interferon-beta production	3.023782e-4
GO:0008637	apoptotic mitochondrial changes	3.038118e-4
GO:0048584	positive regulation of response to stimulus	3.044164e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.057860e-4
GO:0032922	circadian regulation of gene expression	3.060637e-4
GO:0045664	regulation of neuron differentiation	3.096967e-4
GO:0031442	positive regulation of mRNA 3'-end processing	3.098517e-4
GO:0031290	retinal ganglion cell axon guidance	3.149994e-4
GO:0007566	embryo implantation	3.214907e-4
GO:0031325	positive regulation of cellular metabolic process	3.245810e-4
GO:0048468	cell development	3.255446e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3.260259e-4
GO:0061035	regulation of cartilage development	3.269381e-4
GO:0014032	neural crest cell development	3.303739e-4
GO:0060045	positive regulation of cardiac muscle cell proliferation	3.316749e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	3.322771e-4
GO:0002821	positive regulation of adaptive immune response	3.324950e-4
GO:0048641	regulation of skeletal muscle tissue development	3.388167e-4
GO:0007626	locomotory behavior	3.422352e-4
GO:0000305	response to oxygen radical	3.460772e-4
GO:2000191	regulation of fatty acid transport	3.464679e-4
GO:0019226	transmission of nerve impulse	3.479649e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	3.485299e-4
GO:0080135	regulation of cellular response to stress	3.534338e-4
GO:0032868	response to insulin stimulus	3.542966e-4
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	3.547819e-4
GO:0015828	tyrosine transport	3.568682e-4
GO:0060350	endochondral bone morphogenesis	3.635859e-4
GO:0048069	eye pigmentation	3.643714e-4
GO:0006808	regulation of nitrogen utilization	3.659384e-4
GO:0070665	positive regulation of leukocyte proliferation	3.747458e-4
GO:0010720	positive regulation of cell development	3.821318e-4
GO:0046148	pigment biosynthetic process	3.834703e-4
GO:0009611	response to wounding	3.881168e-4
GO:0016050	vesicle organization	3.903204e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	3.966605e-4
GO:0007506	gonadal mesoderm development	4.002276e-4
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	4.020181e-4
GO:2000193	positive regulation of fatty acid transport	4.078511e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	4.224671e-4
GO:0035265	organ growth	4.344816e-4
GO:0030111	regulation of Wnt receptor signaling pathway	4.494196e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	4.537981e-4
GO:0032388	positive regulation of intracellular transport	4.570304e-4
GO:0030155	regulation of cell adhesion	4.655480e-4
GO:0030888	regulation of B cell proliferation	4.720335e-4
GO:0090316	positive regulation of intracellular protein transport	4.730331e-4
GO:0042541	hemoglobin biosynthetic process	4.862361e-4
GO:0014031	mesenchymal cell development	4.955041e-4
GO:0060161	positive regulation of dopamine receptor signaling pathway	4.964370e-4
GO:0051270	regulation of cellular component movement	4.977828e-4
GO:0061136	regulation of proteasomal protein catabolic process	4.982510e-4
GO:0045639	positive regulation of myeloid cell differentiation	4.994588e-4
GO:0050769	positive regulation of neurogenesis	4.998846e-4
GO:0045666	positive regulation of neuron differentiation	5.065355e-4
GO:0006801	superoxide metabolic process	5.068963e-4
GO:0001539	ciliary or flagellar motility	5.176532e-4
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	5.315576e-4
GO:0048546	digestive tract morphogenesis	5.414134e-4
GO:0007274	neuromuscular synaptic transmission	5.432187e-4
GO:0001659	temperature homeostasis	5.484985e-4
GO:0051246	regulation of protein metabolic process	5.613886e-4
GO:0048639	positive regulation of developmental growth	5.623870e-4
GO:0010043	response to zinc ion	5.657647e-4
GO:0045732	positive regulation of protein catabolic process	5.666388e-4
GO:0035564	regulation of kidney size	5.686254e-4
GO:0035247	peptidyl-arginine omega-N-methylation	5.686254e-4
GO:0006207	'de novo' pyrimidine base biosynthetic process	5.686254e-4
GO:0019303	D-ribose catabolic process	5.843482e-4
GO:0035246	peptidyl-arginine N-methylation	5.903973e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0045329	carnitine biosynthetic process	1.739479e-10
GO:0044205	'de novo' UMP biosynthetic process	3.869907e-10
GO:0061181	regulation of chondrocyte development	5.535689e-9
GO:0046491	L-methylmalonyl-CoA metabolic process	6.496424e-9
GO:0051127	positive regulation of actin nucleation	1.070125e-8
GO:0006207	'de novo' pyrimidine base biosynthetic process	4.301530e-8
GO:0044271	cellular nitrogen compound biosynthetic process	8.328103e-8
GO:0051125	regulation of actin nucleation	8.485312e-8
GO:0070602	regulation of centromeric sister chromatid cohesion	1.458715e-7
GO:0042327	positive regulation of phosphorylation	2.363159e-7
GO:0045937	positive regulation of phosphate metabolic process	2.601390e-7
GO:0060676	ureteric bud formation	2.772766e-7
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	4.489915e-7
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	4.851159e-7
GO:0045058	T cell selection	5.420874e-7
GO:0006222	UMP biosynthetic process	5.518298e-7
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.816195e-7
GO:0002689	negative regulation of leukocyte chemotaxis	9.754006e-7
GO:0019433	triglyceride catabolic process	1.113722e-6
GO:0006578	betaine biosynthetic process	1.348628e-6
GO:0001934	positive regulation of protein phosphorylation	1.452079e-6
GO:0031579	membrane raft organization	1.538602e-6
GO:0007063	regulation of sister chromatid cohesion	1.538602e-6
GO:0002688	regulation of leukocyte chemotaxis	1.599703e-6
GO:0050854	regulation of antigen receptor-mediated signaling pathway	2.049660e-6
GO:0035414	negative regulation of catenin import into nucleus	2.066495e-6
GO:0032423	regulation of mismatch repair	2.132954e-6
GO:0002685	regulation of leukocyte migration	2.184158e-6
GO:0008283	cell proliferation	2.251857e-6
GO:0010463	mesenchymal cell proliferation	2.877702e-6
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	3.458473e-6
GO:2001051	positive regulation of tendon cell differentiation	4.521977e-6
GO:0021509	roof plate formation	4.521977e-6
GO:0001923	B-1 B cell differentiation	4.521977e-6
GO:0009124	nucleoside monophosphate biosynthetic process	4.600933e-6
GO:0048844	artery morphogenesis	5.229674e-6
GO:0046464	acylglycerol catabolic process	5.256590e-6
GO:0001501	skeletal system development	5.308475e-6
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	5.508570e-6
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	5.571553e-6
GO:0048488	synaptic vesicle endocytosis	6.085194e-6
GO:0007033	vacuole organization	6.355870e-6
GO:0072283	metanephric renal vesicle morphogenesis	7.308575e-6
GO:0051052	regulation of DNA metabolic process	7.833625e-6
GO:0043383	negative T cell selection	8.501153e-6
GO:0043570	maintenance of DNA repeat elements	9.103623e-6
GO:0002686	negative regulation of leukocyte migration	1.009899e-5
GO:0034694	response to prostaglandin stimulus	1.109656e-5
GO:0033077	T cell differentiation in thymus	1.275003e-5
GO:0034374	low-density lipoprotein particle remodeling	1.308020e-5
GO:0035674	tricarboxylic acid transmembrane transport	1.321893e-5
GO:0046112	nucleobase biosynthetic process	1.397687e-5
GO:0072077	renal vesicle morphogenesis	1.401018e-5
GO:0050852	T cell receptor signaling pathway	1.521475e-5
GO:0048489	synaptic vesicle transport	1.570780e-5
GO:0010269	response to selenium ion	1.641357e-5
GO:0042632	cholesterol homeostasis	1.782456e-5
GO:0070836	caveola assembly	1.799828e-5
GO:0070373	negative regulation of ERK1 and ERK2 cascade	1.967860e-5
GO:0045061	thymic T cell selection	2.031912e-5
GO:0001956	positive regulation of neurotransmitter secretion	2.274640e-5
GO:0033484	nitric oxide homeostasis	2.298094e-5
GO:0001932	regulation of protein phosphorylation	2.421687e-5
GO:0046503	glycerolipid catabolic process	2.444815e-5
GO:0009156	ribonucleoside monophosphate biosynthetic process	2.456793e-5
GO:0045060	negative thymic T cell selection	2.561659e-5
GO:0071379	cellular response to prostaglandin stimulus	3.203065e-5
GO:0031401	positive regulation of protein modification process	3.373985e-5
GO:0021870	Cajal-Retzius cell differentiation	3.610885e-5
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	3.610885e-5
GO:0006432	phenylalanyl-tRNA aminoacylation	3.610885e-5
GO:0022603	regulation of anatomical structure morphogenesis	4.269556e-5
GO:0055088	lipid homeostasis	4.540745e-5
GO:0035412	regulation of catenin import into nucleus	4.671703e-5
GO:0048554	positive regulation of metalloenzyme activity	4.901438e-5
GO:0031167	rRNA methylation	4.901438e-5
GO:0050856	regulation of T cell receptor signaling pathway	5.151630e-5
GO:0060840	artery development	5.592987e-5
GO:0009437	carnitine metabolic process	5.673702e-5
GO:0060688	regulation of morphogenesis of a branching structure	5.692599e-5
GO:0007220	Notch receptor processing	6.190328e-5
GO:0031399	regulation of protein modification process	6.388109e-5
GO:0009309	amine biosynthetic process	6.825259e-5
GO:0072087	renal vesicle development	7.126589e-5
GO:0000723	telomere maintenance	7.392920e-5
GO:0015746	citrate transport	8.054352e-5
GO:0050701	interleukin-1 secretion	8.403491e-5
GO:0051338	regulation of transferase activity	8.829651e-5
GO:0032876	negative regulation of DNA endoreduplication	9.532104e-5
GO:0060267	positive regulation of respiratory burst	9.532104e-5
GO:0032612	interleukin-1 production	9.532104e-5
GO:0000154	rRNA modification	9.532104e-5
GO:0051606	detection of stimulus	9.541336e-5
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	9.796499e-5
GO:0042159	lipoprotein catabolic process	9.796499e-5
GO:0010524	positive regulation of calcium ion transport into cytosol	1.005603e-4
GO:0051983	regulation of chromosome segregation	1.023451e-4
GO:0009123	nucleoside monophosphate metabolic process	1.053041e-4
GO:0019752	carboxylic acid metabolic process	1.068266e-4
GO:0006520	cellular amino acid metabolic process	1.110158e-4
GO:0001765	membrane raft assembly	1.117051e-4
GO:0032273	positive regulation of protein polymerization	1.211446e-4
GO:0032200	telomere organization	1.260726e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1.264550e-4
GO:0048485	sympathetic nervous system development	1.348024e-4
GO:0006641	triglyceride metabolic process	1.348956e-4
GO:2000027	regulation of organ morphogenesis	1.354359e-4
GO:0061325	cell proliferation involved in outflow tract morphogenesis	1.365613e-4
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	1.365613e-4
GO:0071422	succinate transmembrane transport	1.368564e-4
GO:0002121	inter-male aggressive behavior	1.368564e-4
GO:0042180	cellular ketone metabolic process	1.375481e-4
GO:0018130	heterocycle biosynthetic process	1.386267e-4
GO:0008652	cellular amino acid biosynthetic process	1.403979e-4
GO:0014812	muscle cell migration	1.494568e-4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1.528228e-4
GO:0009161	ribonucleoside monophosphate metabolic process	1.541988e-4
GO:0032268	regulation of cellular protein metabolic process	1.612752e-4
GO:0034654	nucleobase-containing compound biosynthetic process	1.637747e-4
GO:0015871	choline transport	1.711127e-4
GO:0035229	positive regulation of glutamate-cysteine ligase activity	1.737039e-4
GO:0042110	T cell activation	1.827936e-4
GO:0032270	positive regulation of cellular protein metabolic process	1.875578e-4
GO:0006082	organic acid metabolic process	1.884528e-4
GO:0043488	regulation of mRNA stability	1.886233e-4
GO:0050775	positive regulation of dendrite morphogenesis	1.902689e-4
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	1.907966e-4
GO:0009791	post-embryonic development	1.925698e-4
GO:0009950	dorsal/ventral axis specification	2.000841e-4
GO:0050818	regulation of coagulation	2.006329e-4
GO:0042325	regulation of phosphorylation	2.087440e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	2.112728e-4
GO:0060982	coronary artery morphogenesis	2.122234e-4
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	2.231648e-4
GO:0009218	pyrimidine ribonucleotide metabolic process	2.231648e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2.231648e-4
GO:0050663	cytokine secretion	2.242921e-4
GO:0046007	negative regulation of activated T cell proliferation	2.380002e-4
GO:0009260	ribonucleotide biosynthetic process	2.430783e-4
GO:0060993	kidney morphogenesis	2.473740e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.476428e-4
GO:0007156	homophilic cell adhesion	2.482476e-4
GO:0001933	negative regulation of protein phosphorylation	2.552119e-4
GO:2000104	negative regulation of DNA-dependent DNA replication	2.607401e-4
GO:0043487	regulation of RNA stability	2.657660e-4
GO:0010717	regulation of epithelial to mesenchymal transition	2.735289e-4
GO:0003382	epithelial cell morphogenesis	2.756091e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	2.767952e-4
GO:0007062	sister chromatid cohesion	2.801988e-4
GO:2000679	positive regulation of transcription regulatory region DNA binding	2.810409e-4
GO:0043270	positive regulation of ion transport	2.820258e-4
GO:0051409	response to nitrosative stress	2.880557e-4
GO:0043549	regulation of kinase activity	2.891343e-4
GO:0030282	bone mineralization	2.991480e-4
GO:0060231	mesenchymal to epithelial transition	2.992850e-4
GO:0046642	negative regulation of alpha-beta T cell proliferation	2.999946e-4
GO:0009308	amine metabolic process	3.116391e-4
GO:0009165	nucleotide biosynthetic process	3.171014e-4
GO:0051590	positive regulation of neurotransmitter transport	3.175658e-4
GO:0042326	negative regulation of phosphorylation	3.303626e-4
GO:0044281	small molecule metabolic process	3.476306e-4
GO:0006638	neutral lipid metabolic process	3.497966e-4
GO:0015813	L-glutamate transport	3.574381e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	3.577141e-4
GO:0008285	negative regulation of cell proliferation	3.697354e-4
GO:0019220	regulation of phosphate metabolic process	3.845080e-4
GO:0043984	histone H4-K16 acetylation	3.943972e-4
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	4.001531e-4
GO:0051054	positive regulation of DNA metabolic process	4.033802e-4
GO:0072273	metanephric nephron morphogenesis	4.108628e-4
GO:0045740	positive regulation of DNA replication	4.270793e-4
GO:0007605	sensory perception of sound	4.477830e-4
GO:0071407	cellular response to organic cyclic compound	4.489244e-4
GO:0002683	negative regulation of immune system process	4.612378e-4
GO:0032469	endoplasmic reticulum calcium ion homeostasis	4.635117e-4
GO:0044093	positive regulation of molecular function	4.723208e-4
GO:0051246	regulation of protein metabolic process	4.882926e-4
GO:0050954	sensory perception of mechanical stimulus	5.001196e-4
GO:0046785	microtubule polymerization	5.071247e-4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	5.079098e-4
GO:0048538	thymus development	5.317686e-4
GO:0051928	positive regulation of calcium ion transport	5.331871e-4
GO:0045936	negative regulation of phosphate metabolic process	5.355632e-4
GO:0006577	betaine metabolic process	5.569013e-4
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	5.680332e-4
GO:0051348	negative regulation of transferase activity	5.689807e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	5.873854e-4
GO:0010886	positive regulation of cholesterol storage	5.873854e-4
GO:0060638	mesenchymal-epithelial cell signaling	6.140873e-4
GO:0010564	regulation of cell cycle process	6.140995e-4
GO:0006029	proteoglycan metabolic process	6.262472e-4
GO:0045807	positive regulation of endocytosis	6.312085e-4
GO:0000188	inactivation of MAPK activity	6.449884e-4
GO:0006662	glycerol ether metabolic process	6.529104e-4
GO:0048255	mRNA stabilization	6.661292e-4
GO:0015800	acidic amino acid transport	6.801879e-4
GO:0033674	positive regulation of kinase activity	6.847004e-4
GO:0043407	negative regulation of MAP kinase activity	7.139330e-4
GO:0006275	regulation of DNA replication	7.274996e-4
GO:0015697	quaternary ammonium group transport	7.289050e-4
GO:0010837	regulation of keratinocyte proliferation	7.289050e-4
GO:0007569	cell aging	7.492785e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	7.656728e-4
GO:0050703	interleukin-1 alpha secretion	7.749323e-4
GO:0007402	ganglion mother cell fate determination	7.749323e-4
GO:0008052	sensory organ boundary specification	7.749323e-4
GO:0050860	negative regulation of T cell receptor signaling pathway	8.304589e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	8.345548e-4
GO:0007267	cell-cell signaling	8.391278e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	8.459736e-4
GO:0035058	nonmotile primary cilium assembly	8.597342e-4
GO:0071243	cellular response to arsenic-containing substance	8.678480e-4
GO:0031954	positive regulation of protein autophosphorylation	9.153229e-4
GO:0030098	lymphocyte differentiation	9.433199e-4
GO:0071044	histone mRNA catabolic process	9.607022e-4
GO:0010608	posttranscriptional regulation of gene expression	1.009466e-3
GO:0010738	regulation of protein kinase A signaling cascade	1.019323e-3
GO:0006639	acylglycerol metabolic process	1.045476e-3
GO:0060547	negative regulation of necrotic cell death	1.055639e-3
GO:0045019	negative regulation of nitric oxide biosynthetic process	1.055639e-3
GO:0050773	regulation of dendrite development	1.064124e-3
GO:0045540	regulation of cholesterol biosynthetic process	1.089068e-3
GO:0030204	chondroitin sulfate metabolic process	1.089068e-3
GO:0043368	positive T cell selection	1.103396e-3
GO:0003215	cardiac right ventricle morphogenesis	1.121493e-3
GO:0021756	striatum development	1.129137e-3
GO:0010469	regulation of receptor activity	1.149036e-3
GO:0001919	regulation of receptor recycling	1.150656e-3
GO:0034660	ncRNA metabolic process	1.156919e-3
GO:0044283	small molecule biosynthetic process	1.157836e-3
GO:0030838	positive regulation of actin filament polymerization	1.187184e-3
GO:0051347	positive regulation of transferase activity	1.192422e-3
GO:0042953	lipoprotein transport	1.256688e-3
GO:0010885	regulation of cholesterol storage	1.256688e-3
GO:0018904	organic ether metabolic process	1.260520e-3
GO:0032879	regulation of localization	1.265359e-3
GO:0060075	regulation of resting membrane potential	1.271970e-3
GO:0002690	positive regulation of leukocyte chemotaxis	1.290233e-3
GO:0006282	regulation of DNA repair	1.328259e-3
GO:0044106	cellular amine metabolic process	1.328990e-3
GO:0048854	brain morphogenesis	1.333578e-3
GO:0090317	negative regulation of intracellular protein transport	1.354486e-3
GO:0002687	positive regulation of leukocyte migration	1.377603e-3
GO:0034470	ncRNA processing	1.380237e-3
GO:0010665	regulation of cardiac muscle cell apoptosis	1.388150e-3
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	1.395843e-3
GO:0006206	pyrimidine base metabolic process	1.397484e-3
GO:0034383	low-density lipoprotein particle clearance	1.436908e-3
GO:0006642	triglyceride mobilization	1.436908e-3
GO:0031342	negative regulation of cell killing	1.444941e-3
GO:0001921	positive regulation of receptor recycling	1.468877e-3
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	1.476170e-3
GO:0009968	negative regulation of signal transduction	1.509827e-3
GO:0051450	myoblast proliferation	1.553215e-3
GO:0060973	cell migration involved in heart development	1.579289e-3
GO:0051223	regulation of protein transport	1.580843e-3
GO:0060249	anatomical structure homeostasis	1.610359e-3
GO:0050820	positive regulation of coagulation	1.621345e-3
GO:0043409	negative regulation of MAPKKK cascade	1.630617e-3
GO:0045860	positive regulation of protein kinase activity	1.638244e-3
GO:0051270	regulation of cellular component movement	1.649049e-3
GO:0015711	organic anion transport	1.669939e-3
GO:0051224	negative regulation of protein transport	1.679977e-3
GO:0007030	Golgi organization	1.685705e-3
GO:0090329	regulation of DNA-dependent DNA replication	1.687793e-3
GO:0006467	protein thiol-disulfide exchange	1.705465e-3
GO:0007638	mechanosensory behavior	1.733166e-3
GO:2000145	regulation of cell motility	1.776828e-3
GO:0090183	regulation of kidney development	1.780496e-3
GO:0071333	cellular response to glucose stimulus	1.782821e-3
GO:0001822	kidney development	1.795928e-3
GO:0045859	regulation of protein kinase activity	1.801288e-3
GO:0010884	positive regulation of lipid storage	1.813674e-3
GO:0043001	Golgi to plasma membrane protein transport	1.829001e-3
GO:0007219	Notch signaling pathway	1.860709e-3
GO:0050877	neurological system process	1.919044e-3
GO:0031400	negative regulation of protein modification process	2.003048e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.032955e-3
GO:0072088	nephron epithelium morphogenesis	2.040371e-3
GO:0060263	regulation of respiratory burst	2.047404e-3
GO:0030217	T cell differentiation	2.072823e-3
GO:0042640	anagen	2.076014e-3
GO:0032914	positive regulation of transforming growth factor beta1 production	2.143959e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	2.168169e-3
GO:0010743	regulation of macrophage derived foam cell differentiation	2.168169e-3
GO:0030334	regulation of cell migration	2.170075e-3
GO:0040012	regulation of locomotion	2.213915e-3
GO:0001957	intramembranous ossification	2.244850e-3
GO:0009620	response to fungus	2.258089e-3
GO:0071322	cellular response to carbohydrate stimulus	2.260784e-3
GO:0007040	lysosome organization	2.287627e-3
GO:0060013	righting reflex	2.290875e-3
GO:0007096	regulation of exit from mitosis	2.290875e-3
GO:0007176	regulation of epidermal growth factor-activated receptor activity	2.294009e-3
GO:0045668	negative regulation of osteoblast differentiation	2.301479e-3
GO:0051247	positive regulation of protein metabolic process	2.307744e-3
GO:0050851	antigen receptor-mediated signaling pathway	2.308852e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	2.324692e-3
GO:0072001	renal system development	2.363370e-3
GO:0042982	amyloid precursor protein metabolic process	2.371332e-3
GO:0061033	secretion by lung epithelial cell involved in lung growth	2.389889e-3
GO:0050702	interleukin-1 beta secretion	2.389889e-3
GO:0003338	metanephros morphogenesis	2.414394e-3
GO:0046640	regulation of alpha-beta T cell proliferation	2.414394e-3
GO:0002003	angiotensin maturation	2.419846e-3
GO:0009629	response to gravity	2.424422e-3
GO:0045022	early endosome to late endosome transport	2.619925e-3
GO:0032611	interleukin-1 beta production	2.654535e-3
GO:0009826	unidimensional cell growth	2.654535e-3
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	2.664926e-3
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	2.667587e-3
GO:0090181	regulation of cholesterol metabolic process	2.680766e-3
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	2.700517e-3
GO:0002764	immune response-regulating signaling pathway	2.735586e-3
GO:0061308	cardiac neural crest cell development involved in heart development	2.771502e-3
GO:0031952	regulation of protein autophosphorylation	2.829660e-3
GO:0008202	steroid metabolic process	2.831214e-3
GO:0006469	negative regulation of protein kinase activity	2.853635e-3
GO:0010994	free ubiquitin chain polymerization	2.869074e-3
GO:0040009	regulation of growth rate	2.938582e-3
GO:0032271	regulation of protein polymerization	3.070255e-3
GO:0034369	plasma lipoprotein particle remodeling	3.113289e-3
GO:0031341	regulation of cell killing	3.162241e-3
GO:0001678	cellular glucose homeostasis	3.218670e-3
GO:2000677	regulation of transcription regulatory region DNA binding	3.259686e-3
GO:0002521	leukocyte differentiation	3.271546e-3
GO:0007608	sensory perception of smell	3.287099e-3
GO:0051050	positive regulation of transport	3.293374e-3
GO:0021544	subpallium development	3.308859e-3
GO:0061032	visceral serous pericardium development	3.329001e-3
GO:0001816	cytokine production	3.353067e-3
GO:0060348	bone development	3.412908e-3
GO:0009069	serine family amino acid metabolic process	3.464515e-3
GO:0003211	cardiac ventricle formation	3.472225e-3
GO:0048935	peripheral nervous system neuron development	3.486822e-3
GO:0010656	negative regulation of muscle cell apoptosis	3.618412e-3
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	3.618412e-3
GO:0006893	Golgi to plasma membrane transport	3.650271e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	3.672048e-3
GO:0007250	activation of NF-kappaB-inducing kinase activity	3.763725e-3
GO:0009414	response to water deprivation	3.802937e-3
GO:0050920	regulation of chemotaxis	3.822770e-3
GO:0030836	positive regulation of actin filament depolymerization	3.913825e-3
GO:0042308	negative regulation of protein import into nucleus	3.942204e-3
GO:0051495	positive regulation of cytoskeleton organization	3.980046e-3
GO:0001771	immunological synapse formation	4.065854e-3
GO:0007129	synapsis	4.067840e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	4.175664e-3
GO:0070664	negative regulation of leukocyte proliferation	4.183354e-3
GO:0003207	cardiac chamber formation	4.228411e-3
GO:0002429	immune response-activating cell surface receptor signaling pathway	4.254287e-3
GO:0002253	activation of immune response	4.292489e-3
GO:0009112	nucleobase metabolic process	4.331607e-3
GO:0050665	hydrogen peroxide biosynthetic process	4.341492e-3
GO:0022604	regulation of cell morphogenesis	4.370486e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	4.416914e-3
GO:0030317	sperm motility	4.421487e-3
GO:0006221	pyrimidine nucleotide biosynthetic process	4.443645e-3
GO:0051089	constitutive protein ectodomain proteolysis	4.510749e-3
GO:0021757	caudate nucleus development	4.510749e-3
GO:0021758	putamen development	4.510749e-3
GO:0042594	response to starvation	4.518886e-3
GO:0061097	regulation of protein tyrosine kinase activity	4.612525e-3
GO:0046394	carboxylic acid biosynthetic process	4.653749e-3
GO:0070192	chromosome organization involved in meiosis	4.732558e-3
GO:0003219	cardiac right ventricle formation	4.773264e-3
GO:0016525	negative regulation of angiogenesis	4.776148e-3
GO:0033673	negative regulation of kinase activity	4.857329e-3
GO:0030193	regulation of blood coagulation	5.014723e-3
GO:0008334	histone mRNA metabolic process	5.019745e-3
GO:0002328	pro-B cell differentiation	5.019745e-3
GO:0072522	purine-containing compound biosynthetic process	5.046907e-3
GO:0001775	cell activation	5.132669e-3
GO:0072028	nephron morphogenesis	5.158212e-3
GO:0032066	nucleolus to nucleoplasm transport	5.160699e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	5.283412e-3
GO:0007032	endosome organization	5.421756e-3
GO:0050906	detection of stimulus involved in sensory perception	5.435838e-3
GO:0048483	autonomic nervous system development	5.518615e-3
GO:0035022	positive regulation of Rac protein signal transduction	5.525429e-3
GO:0032924	activin receptor signaling pathway	5.525429e-3
GO:0030432	peristalsis	5.540518e-3
GO:0050435	beta-amyloid metabolic process	5.577807e-3
GO:0030540	female genitalia development	5.597800e-3
GO:0060562	epithelial tube morphogenesis	5.650818e-3
GO:0007568	aging	5.698822e-3
GO:0006509	membrane protein ectodomain proteolysis	5.778224e-3
GO:0030182	neuron differentiation	5.782707e-3
GO:0060055	angiogenesis involved in wound healing	5.815205e-3
GO:0033483	gas homeostasis	5.815205e-3
GO:0006364	rRNA processing	5.851333e-3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	5.921946e-3
GO:0042993	positive regulation of transcription factor import into nucleus	5.925476e-3
GO:0042130	negative regulation of T cell proliferation	6.023953e-3
GO:0060675	ureteric bud morphogenesis	6.090760e-3
GO:0061307	cardiac neural crest cell differentiation involved in heart development	6.099685e-3
GO:0035690	cellular response to drug	6.179941e-3
GO:0001960	negative regulation of cytokine-mediated signaling pathway	6.179941e-3
GO:0006171	cAMP biosynthetic process	6.345894e-3
GO:0034113	heterotypic cell-cell adhesion	6.394156e-3
GO:0018209	peptidyl-serine modification	6.465582e-3
GO:0008064	regulation of actin polymerization or depolymerization	6.469595e-3
GO:0002118	aggressive behavior	6.475654e-3
GO:0007342	fusion of sperm to egg plasma membrane	6.475654e-3
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	6.654527e-3
GO:0007600	sensory perception	6.765389e-3
GO:0030514	negative regulation of BMP signaling pathway	6.783208e-3
GO:0006213	pyrimidine nucleoside metabolic process	6.855630e-3
GO:0035108	limb morphogenesis	6.857690e-3
GO:0033619	membrane protein proteolysis	6.956730e-3
GO:0072528	pyrimidine-containing compound biosynthetic process	7.046614e-3
GO:0006468	protein phosphorylation	7.057591e-3
GO:0048858	cell projection morphogenesis	7.081628e-3
GO:0007268	synaptic transmission	7.168881e-3
GO:0000045	autophagic vacuole assembly	7.269424e-3
GO:0071827	plasma lipoprotein particle organization	7.333559e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	7.435587e-3
GO:0023057	negative regulation of signaling	7.471815e-3
GO:0048705	skeletal system morphogenesis	7.551751e-3
GO:0002682	regulation of immune system process	7.657354e-3
GO:0016337	cell-cell adhesion	7.720947e-3
GO:0009593	detection of chemical stimulus	7.781612e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	7.781674e-3
GO:0043393	regulation of protein binding	7.864460e-3
GO:0010648	negative regulation of cell communication	7.918540e-3
GO:0007346	regulation of mitotic cell cycle	7.987888e-3
GO:0050672	negative regulation of lymphocyte proliferation	8.009298e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	8.305576e-3
GO:0006363	termination of RNA polymerase I transcription	8.305576e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	8.305608e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	8.305608e-3
GO:0034201	response to oleic acid	8.305608e-3
GO:0035910	ascending aorta morphogenesis	8.305608e-3
GO:0006790	sulfur compound metabolic process	8.702188e-3
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	8.727335e-3
GO:0016072	rRNA metabolic process	8.752351e-3
GO:0045821	positive regulation of glycolysis	8.758883e-3
GO:0042987	amyloid precursor protein catabolic process	8.758883e-3
GO:0009116	nucleoside metabolic process	8.763625e-3
GO:0071900	regulation of protein serine/threonine kinase activity	8.790775e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	8.839894e-3
GO:0090068	positive regulation of cell cycle process	9.037588e-3
GO:0042306	regulation of protein import into nucleus	9.086987e-3
GO:0021953	central nervous system neuron differentiation	9.180605e-3
GO:0031223	auditory behavior	9.308525e-3
GO:0001947	heart looping	9.376369e-3
GO:0048812	neuron projection morphogenesis	9.388600e-3
GO:0060571	morphogenesis of an epithelial fold	9.673662e-3
GO:0051569	regulation of histone H3-K4 methylation	9.716105e-3
GO:0032990	cell part morphogenesis	9.834401e-3
GO:0033137	negative regulation of peptidyl-serine phosphorylation	9.945278e-3
GO:0046649	lymphocyte activation	1.006578e-2
GO:0002757	immune response-activating signal transduction	1.011658e-2
GO:0034763	negative regulation of transmembrane transport	1.018153e-2
GO:0042117	monocyte activation	1.021814e-2
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	1.021814e-2
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.021814e-2
GO:0021905	forebrain-midbrain boundary formation	1.021814e-2
GO:0003322	pancreatic A cell development	1.021814e-2
GO:0031109	microtubule polymerization or depolymerization	1.022062e-2
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.022062e-2
GO:0050673	epithelial cell proliferation	1.028624e-2
GO:0050855	regulation of B cell receptor signaling pathway	1.034796e-2
GO:0001657	ureteric bud development	1.038702e-2
GO:0046058	cAMP metabolic process	1.063510e-2
GO:0045026	plasma membrane fusion	1.063534e-2
GO:0051549	positive regulation of keratinocyte migration	1.063534e-2
GO:0051276	chromosome organization	1.064241e-2
GO:0006418	tRNA aminoacylation for protein translation	1.066055e-2
GO:0021773	striatal medium spiny neuron differentiation	1.074279e-2
GO:0042492	gamma-delta T cell differentiation	1.078036e-2
GO:0009100	glycoprotein metabolic process	1.086776e-2
GO:0009953	dorsal/ventral pattern formation	1.091520e-2
GO:0030832	regulation of actin filament length	1.092782e-2
GO:0060173	limb development	1.104271e-2
GO:0008206	bile acid metabolic process	1.127791e-2
GO:0070201	regulation of establishment of protein localization	1.129889e-2
GO:0009120	deoxyribonucleoside metabolic process	1.134213e-2
GO:0030301	cholesterol transport	1.139693e-2
GO:0022612	gland morphogenesis	1.141060e-2
GO:0033157	regulation of intracellular protein transport	1.141861e-2
GO:0051318	G1 phase	1.142268e-2
GO:0090023	positive regulation of neutrophil chemotaxis	1.142268e-2
GO:0045321	leukocyte activation	1.146886e-2
GO:0048814	regulation of dendrite morphogenesis	1.154757e-2
GO:0071902	positive regulation of protein serine/threonine kinase activity	1.156600e-2
GO:0045070	positive regulation of viral genome replication	1.167350e-2
GO:0010828	positive regulation of glucose transport	1.174752e-2
GO:0002064	epithelial cell development	1.175062e-2
GO:0040007	growth	1.177717e-2
GO:0048667	cell morphogenesis involved in neuron differentiation	1.178493e-2
GO:0006534	cysteine metabolic process	1.184116e-2
GO:0021515	cell differentiation in spinal cord	1.193745e-2
GO:0030901	midbrain development	1.206357e-2
GO:0051216	cartilage development	1.217181e-2
GO:0071622	regulation of granulocyte chemotaxis	1.221808e-2
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	1.224213e-2
GO:0006968	cellular defense response	1.224213e-2
GO:0006164	purine nucleotide biosynthetic process	1.227722e-2
GO:0010769	regulation of cell morphogenesis involved in differentiation	1.236474e-2