Novel motif:1

name:	motif1_TCGNAG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0071460	cellular response to cell-matrix adhesion	2.515949e-10
GO:0010994	free ubiquitin chain polymerization	8.271057e-9
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.905711e-8
GO:0006379	mRNA cleavage	3.770924e-8
GO:0034470	ncRNA processing	1.021054e-7
GO:0040040	thermosensory behavior	1.534554e-7
GO:0006268	DNA unwinding involved in replication	1.858830e-7
GO:2000002	negative regulation of DNA damage checkpoint	1.970207e-7
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.970207e-7
GO:0021551	central nervous system morphogenesis	1.970207e-7
GO:0021588	cerebellum formation	1.970207e-7
GO:0021562	vestibulocochlear nerve development	2.511725e-7
GO:0097039	protein linear polyubiquitination	3.134306e-7
GO:0006853	carnitine shuttle	4.342535e-7
GO:0051549	positive regulation of keratinocyte migration	5.450166e-7
GO:0016233	telomere capping	6.206359e-7
GO:0051488	activation of anaphase-promoting complex activity	6.314233e-7
GO:0019087	transformation of host cell by virus	9.882323e-7
GO:0031848	protection from non-homologous end joining at telomere	1.411093e-6
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	3.231447e-6
GO:0006406	mRNA export from nucleus	4.674314e-6
GO:0021604	cranial nerve structural organization	4.944376e-6
GO:0006353	transcription termination, DNA-dependent	5.453594e-6
GO:0000115	regulation of transcription involved in S phase of mitotic cell cycle	7.268597e-6
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	9.352441e-6
GO:0090103	cochlea morphogenesis	9.893706e-6
GO:0030574	collagen catabolic process	1.018333e-5
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.057255e-5
GO:0060670	branching involved in embryonic placenta morphogenesis	1.321742e-5
GO:0060669	embryonic placenta morphogenesis	1.346355e-5
GO:0048561	establishment of organ orientation	1.388524e-5
GO:0046755	non-lytic virus budding	1.405845e-5
GO:0021602	cranial nerve morphogenesis	1.428249e-5
GO:0015696	ammonium transport	1.433112e-5
GO:0048102	autophagic cell death	1.539656e-5
GO:0090342	regulation of cell aging	1.782236e-5
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.857630e-5
GO:0010498	proteasomal protein catabolic process	1.942331e-5
GO:0023035	CD40 signaling pathway	2.024181e-5
GO:0048702	embryonic neurocranium morphogenesis	2.306710e-5
GO:0051932	synaptic transmission, GABAergic	2.953703e-5
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	3.151521e-5
GO:0008033	tRNA processing	3.300296e-5
GO:0090224	regulation of spindle organization	3.916922e-5
GO:0021603	cranial nerve formation	4.153465e-5
GO:0006544	glycine metabolic process	4.342563e-5
GO:0031442	positive regulation of mRNA 3'-end processing	4.962461e-5
GO:2000774	positive regulation of cellular senescence	5.017668e-5
GO:0035986	senescence-associated heterochromatin focus formation	5.017668e-5
GO:2000772	regulation of cellular senescence	5.169851e-5
GO:2000597	positive regulation of optic nerve formation	5.873194e-5
GO:0061360	optic chiasma development	5.873194e-5
GO:0021633	optic nerve structural organization	5.873194e-5
GO:0035799	ureter maturation	5.873194e-5
GO:0021650	vestibulocochlear nerve formation	5.873194e-5
GO:0001823	mesonephros development	7.830568e-5
GO:0042254	ribosome biogenesis	8.193139e-5
GO:0032365	intracellular lipid transport	8.561012e-5
GO:0006298	mismatch repair	9.214029e-5
GO:0031860	telomeric 3' overhang formation	9.480062e-5
GO:0031081	nuclear pore distribution	9.480062e-5
GO:0090192	regulation of glomerulus development	1.002988e-4
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.072150e-4
GO:0009589	detection of UV	1.072150e-4
GO:0090193	positive regulation of glomerulus development	1.091276e-4
GO:0001302	replicative cell aging	1.097757e-4
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.216964e-4
GO:0021592	fourth ventricle development	1.226802e-4
GO:2000370	positive regulation of clathrin-mediated endocytosis	1.316809e-4
GO:0060606	tube closure	1.329754e-4
GO:0035928	rRNA import into mitochondrion	1.339438e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.340785e-4
GO:2000249	regulation of actin cytoskeleton reorganization	1.462909e-4
GO:0001843	neural tube closure	1.476223e-4
GO:0044243	multicellular organismal catabolic process	1.546206e-4
GO:0001510	RNA methylation	1.592464e-4
GO:0072178	nephric duct morphogenesis	1.653776e-4
GO:0070979	protein K11-linked ubiquitination	1.697155e-4
GO:0006290	pyrimidine dimer repair	1.737908e-4
GO:0014020	primary neural tube formation	1.814523e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.832742e-4
GO:0006405	RNA export from nucleus	1.969051e-4
GO:0009440	cyanate catabolic process	1.989144e-4
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	2.085369e-4
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	2.086190e-4
GO:0006364	rRNA processing	2.091161e-4
GO:0034660	ncRNA metabolic process	2.098342e-4
GO:0009637	response to blue light	2.125631e-4
GO:0006285	base-excision repair, AP site formation	2.573737e-4
GO:0009650	UV protection	2.670660e-4
GO:0030513	positive regulation of BMP signaling pathway	2.721034e-4
GO:0048532	anatomical structure arrangement	2.750080e-4
GO:0031627	telomeric loop formation	2.819905e-4
GO:0030150	protein import into mitochondrial matrix	2.819905e-4
GO:0071585	detoxification of cadmium ion	2.941256e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	3.047904e-4
GO:0051029	rRNA transport	3.167503e-4
GO:0072298	regulation of metanephric glomerulus development	3.209527e-4
GO:0035566	regulation of metanephros size	3.248419e-4
GO:0072176	nephric duct development	3.274949e-4
GO:0007501	mesodermal cell fate specification	3.292783e-4
GO:0060976	coronary vasculature development	3.385720e-4
GO:0032392	DNA geometric change	3.655228e-4
GO:0009235	cobalamin metabolic process	3.712193e-4
GO:0033233	regulation of protein sumoylation	3.725002e-4
GO:0010225	response to UV-C	3.868642e-4
GO:0006398	histone mRNA 3'-end processing	3.892183e-4
GO:0021666	rhombomere 5 formation	4.355341e-4
GO:0021660	rhombomere 3 formation	4.355341e-4
GO:0072177	mesonephric duct development	4.355634e-4
GO:0030433	ER-associated protein catabolic process	4.491393e-4
GO:0001522	pseudouridine synthesis	4.555449e-4
GO:0034389	lipid particle organization	4.632934e-4
GO:0055024	regulation of cardiac muscle tissue development	4.764888e-4
GO:0072171	mesonephric tubule morphogenesis	4.856067e-4
GO:0033683	nucleotide-excision repair, DNA incision	4.901193e-4
GO:0000154	rRNA modification	4.974353e-4
GO:0031507	heterochromatin formation	5.014754e-4
GO:0016569	covalent chromatin modification	5.029655e-4
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	5.069740e-4
GO:0021771	lateral geniculate nucleus development	5.421535e-4
GO:0016570	histone modification	5.581453e-4
GO:0071402	cellular response to lipoprotein particle stimulus	5.676588e-4
GO:0060712	spongiotrophoblast layer development	6.158736e-4
GO:0070734	histone H3-K27 methylation	6.244446e-4
GO:0046784	intronless viral mRNA export from host nucleus	6.354359e-4
GO:0060708	spongiotrophoblast differentiation	6.586479e-4
GO:0060242	contact inhibition	6.649106e-4
GO:0072300	positive regulation of metanephric glomerulus development	7.017052e-4
GO:0045007	depurination	7.196075e-4
GO:0060236	regulation of mitotic spindle organization	7.323798e-4
GO:0006335	DNA replication-dependent nucleosome assembly	7.524317e-4
GO:0032205	negative regulation of telomere maintenance	7.587953e-4
GO:0097029	mature dendritic cell differentiation	7.620489e-4
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	7.643188e-4
GO:0055021	regulation of cardiac muscle tissue growth	7.678393e-4
GO:0010923	negative regulation of phosphatase activity	7.889462e-4
GO:0031915	positive regulation of synaptic plasticity	8.609862e-4
GO:0006284	base-excision repair	8.734585e-4
GO:0022617	extracellular matrix disassembly	9.114523e-4
GO:0015695	organic cation transport	9.425935e-4
GO:0042026	protein refolding	9.697664e-4
GO:0006369	termination of RNA polymerase II transcription	9.770821e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.037949e-3
GO:0035404	histone-serine phosphorylation	1.057752e-3
GO:0060043	regulation of cardiac muscle cell proliferation	1.058921e-3
GO:0050685	positive regulation of mRNA processing	1.070386e-3
GO:0051220	cytoplasmic sequestering of protein	1.078722e-3
GO:0021612	facial nerve structural organization	1.080035e-3
GO:0016072	rRNA metabolic process	1.096278e-3
GO:0006476	protein deacetylation	1.109808e-3
GO:0019532	oxalate transport	1.145267e-3
GO:0032682	negative regulation of chemokine production	1.152848e-3
GO:0032446	protein modification by small protein conjugation	1.154618e-3
GO:0034633	retinol transport	1.158977e-3
GO:0021930	cerebellar granule cell precursor proliferation	1.158977e-3
GO:0072091	regulation of stem cell proliferation	1.198634e-3
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	1.287130e-3
GO:0070086	ubiquitin-dependent endocytosis	1.295249e-3
GO:0034351	negative regulation of glial cell apoptosis	1.309435e-3
GO:0090343	positive regulation of cell aging	1.335684e-3
GO:0060707	trophoblast giant cell differentiation	1.335684e-3
GO:0018022	peptidyl-lysine methylation	1.358558e-3
GO:0017121	phospholipid scrambling	1.380366e-3
GO:0090275	negative regulation of somatostatin secretion	1.407652e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	1.425290e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	1.445765e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.445765e-3
GO:0051154	negative regulation of striated muscle cell differentiation	1.469564e-3
GO:0032984	macromolecular complex disassembly	1.508362e-3
GO:0042823	pyridoxal phosphate biosynthetic process	1.512960e-3
GO:0019348	dolichol metabolic process	1.512960e-3
GO:0043241	protein complex disassembly	1.519638e-3
GO:0030488	tRNA methylation	1.556328e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	1.603943e-3
GO:0043249	erythrocyte maturation	1.603943e-3
GO:0008272	sulfate transport	1.619287e-3
GO:0010172	embryonic body morphogenesis	1.622282e-3
GO:0010912	positive regulation of isomerase activity	1.622898e-3
GO:0032508	DNA duplex unwinding	1.652335e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	1.698326e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	1.699270e-3
GO:0007214	gamma-aminobutyric acid signaling pathway	1.709434e-3
GO:0015909	long-chain fatty acid transport	1.745891e-3
GO:0071169	establishment of protein localization to chromatin	1.773571e-3
GO:2000001	regulation of DNA damage checkpoint	1.776559e-3
GO:0048239	negative regulation of DNA recombination at telomere	1.789689e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	1.789689e-3
GO:0032119	sequestering of zinc ion	1.800736e-3
GO:0006415	translational termination	1.813086e-3
GO:0072180	mesonephric duct morphogenesis	1.820337e-3
GO:0035601	protein deacylation	1.922839e-3
GO:0006301	postreplication repair	1.931095e-3
GO:0055026	negative regulation of cardiac muscle tissue development	1.942426e-3
GO:0071279	cellular response to cobalt ion	1.955829e-3
GO:0021599	abducens nerve formation	1.955829e-3
GO:0010637	negative regulation of mitochondrial fusion	1.955829e-3
GO:0007634	optokinetic behavior	1.955829e-3
GO:0043538	regulation of actin phosphorylation	2.079260e-3
GO:0042941	D-alanine transport	2.079260e-3
GO:0046674	induction of retinal programmed cell death	2.079260e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	2.079260e-3
GO:0001777	T cell homeostatic proliferation	2.079260e-3
GO:0002352	B cell negative selection	2.079260e-3
GO:0032976	release of matrix enzymes from mitochondria	2.079260e-3
GO:0016925	protein sumoylation	2.142819e-3
GO:0001839	neural plate morphogenesis	2.151480e-3
GO:0045292	nuclear mRNA cis splicing, via spliceosome	2.151480e-3
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	2.160955e-3
GO:2000009	negative regulation of protein localization at cell surface	2.189883e-3
GO:0071469	cellular response to alkalinity	2.189883e-3
GO:0018345	protein palmitoylation	2.247083e-3
GO:0034623	cellular macromolecular complex disassembly	2.251657e-3
GO:0006659	phosphatidylserine biosynthetic process	2.264332e-3
GO:0006540	glutamate decarboxylation to succinate	2.282551e-3
GO:0043624	cellular protein complex disassembly	2.338312e-3
GO:0048793	pronephros development	2.349153e-3
GO:0032275	luteinizing hormone secretion	2.445696e-3
GO:0046884	follicle-stimulating hormone secretion	2.445696e-3
GO:0003406	retinal pigment epithelium development	2.445696e-3
GO:0048704	embryonic skeletal system morphogenesis	2.501165e-3
GO:0018026	peptidyl-lysine monomethylation	2.510483e-3
GO:0032088	negative regulation of NF-kappaB transcription factor activity	2.518890e-3
GO:0060023	soft palate development	2.562946e-3
GO:0000022	mitotic spindle elongation	2.592442e-3
GO:0030037	actin filament reorganization involved in cell cycle	2.638035e-3
GO:0016180	snRNA processing	2.644247e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	2.659336e-3
GO:0097152	mesenchymal cell apoptosis	2.659336e-3
GO:0009107	lipoate biosynthetic process	2.659336e-3
GO:0060982	coronary artery morphogenesis	2.659336e-3
GO:0046626	regulation of insulin receptor signaling pathway	2.742439e-3
GO:0042364	water-soluble vitamin biosynthetic process	2.772239e-3
GO:0000959	mitochondrial RNA metabolic process	2.795031e-3
GO:0006546	glycine catabolic process	2.802273e-3
GO:0072385	minus-end-directed organelle transport along microtubule	2.869771e-3
GO:0033235	positive regulation of protein sumoylation	2.896888e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.917686e-3
GO:0055098	response to low-density lipoprotein particle stimulus	2.952362e-3
GO:0090102	cochlea development	3.097091e-3
GO:0009069	serine family amino acid metabolic process	3.102856e-3
GO:0031167	rRNA methylation	3.175219e-3
GO:0042989	sequestering of actin monomers	3.259299e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	3.321510e-3
GO:0001710	mesodermal cell fate commitment	3.326942e-3
GO:0010159	specification of organ position	3.335682e-3
GO:0061013	regulation of mRNA catabolic process	3.339856e-3
GO:0022037	metencephalon development	3.377178e-3
GO:0021754	facial nucleus development	3.443700e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	3.445057e-3
GO:0060272	embryonic skeletal joint morphogenesis	3.498862e-3
GO:0016572	histone phosphorylation	3.659652e-3
GO:0009443	pyridoxal 5'-phosphate salvage	3.712126e-3
GO:0045918	negative regulation of cytolysis	3.713402e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	3.912426e-3
GO:0090402	oncogene-induced senescence	4.063975e-3
GO:0071167	ribonucleoprotein complex import into nucleus	4.139274e-3
GO:0061032	visceral serous pericardium development	4.164725e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.164725e-3
GO:0048210	Golgi vesicle fusion to target membrane	4.164725e-3
GO:0021993	initiation of neural tube closure	4.295576e-3
GO:0006168	adenine salvage	4.295576e-3
GO:0018916	nitrobenzene metabolic process	4.356192e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	4.356192e-3
GO:0006272	leading strand elongation	4.356192e-3
GO:0090129	positive regulation of synapse maturation	4.405651e-3
GO:0060743	epithelial cell maturation involved in prostate gland development	4.487654e-3
GO:0021610	facial nerve morphogenesis	4.491052e-3
GO:0090009	primitive streak formation	4.573054e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	4.573054e-3
GO:0072075	metanephric mesenchyme development	4.596130e-3
GO:0031440	regulation of mRNA 3'-end processing	4.605433e-3
GO:0010458	exit from mitosis	4.636137e-3
GO:0070094	positive regulation of glucagon secretion	4.656558e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	4.751909e-3
GO:0070314	G1 to G0 transition	4.751909e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	4.751909e-3
GO:0035520	monoubiquitinated protein deubiquitination	4.759805e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	4.784087e-3
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	4.931976e-3
GO:0006839	mitochondrial transport	5.011164e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	5.083717e-3
GO:0006363	termination of RNA polymerase I transcription	5.122371e-3
GO:0046501	protoporphyrinogen IX metabolic process	5.200503e-3
GO:0034723	DNA replication-dependent nucleosome organization	5.200503e-3
GO:0060013	righting reflex	5.260030e-3
GO:0060969	negative regulation of gene silencing	5.289063e-3
GO:0072133	metanephric mesenchyme morphogenesis	5.387684e-3
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	5.387913e-3
GO:0006281	DNA repair	5.486993e-3
GO:0090399	replicative senescence	5.492427e-3
GO:0072498	embryonic skeletal joint development	5.534001e-3
GO:0048486	parasympathetic nervous system development	5.638344e-3
GO:0051204	protein insertion into mitochondrial membrane	5.704822e-3
GO:0021561	facial nerve development	5.704822e-3
GO:0072553	terminal button organization	5.749903e-3
GO:0097045	phosphatidylserine exposure on blood platelet	5.749903e-3
GO:0006550	isoleucine catabolic process	5.749903e-3
GO:0009098	leucine biosynthetic process	5.749903e-3
GO:0071569	protein ufmylation	5.794026e-3
GO:0007031	peroxisome organization	5.816845e-3
GO:0097119	postsynaptic density protein 95 clustering	5.883257e-3
GO:0002829	negative regulation of type 2 immune response	5.883257e-3
GO:0097104	postsynaptic membrane assembly	5.883257e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	5.884959e-3
GO:0002149	hypochlorous acid biosynthetic process	5.968702e-3
GO:0097116	gephyrin clustering	5.976271e-3
GO:0021546	rhombomere development	5.985086e-3
GO:0046502	uroporphyrinogen III metabolic process	6.055916e-3
GO:0070366	regulation of hepatocyte differentiation	6.055916e-3
GO:0001672	regulation of chromatin assembly or disassembly	6.062492e-3
GO:0045081	negative regulation of interleukin-10 biosynthetic process	6.095723e-3
GO:0090128	regulation of synapse maturation	6.232050e-3
GO:0001840	neural plate development	6.249930e-3
GO:0035852	horizontal cell localization	6.309205e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	6.309205e-3
GO:0035849	nephric duct elongation	6.309205e-3
GO:0035502	metanephric ureteric bud development	6.309205e-3
GO:0035847	uterine epithelium development	6.309205e-3
GO:0010734	negative regulation of protein glutathionylation	6.309205e-3
GO:0035846	oviduct epithelium development	6.309205e-3
GO:0021548	pons development	6.386242e-3
GO:0060876	semicircular canal formation	6.415942e-3
GO:0060455	negative regulation of gastric acid secretion	6.415942e-3
GO:0032007	negative regulation of TOR signaling cascade	6.437288e-3
GO:0021554	optic nerve development	6.466023e-3
GO:0042942	D-serine transport	6.472050e-3
GO:0046491	L-methylmalonyl-CoA metabolic process	6.472050e-3
GO:0034766	negative regulation of ion transmembrane transport	6.472050e-3
GO:0016575	histone deacetylation	6.594247e-3
GO:0016568	chromatin modification	6.968356e-3
GO:0009304	tRNA transcription	7.019470e-3
GO:0060033	anatomical structure regression	7.319803e-3
GO:0016567	protein ubiquitination	7.729443e-3
GO:0071545	inositol phosphate catabolic process	8.029910e-3
GO:0016576	histone dephosphorylation	8.067388e-3
GO:0006098	pentose-phosphate shunt	8.089548e-3
GO:0008054	cyclin catabolic process	8.217849e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.226966e-3
GO:0061014	positive regulation of mRNA catabolic process	8.297920e-3
GO:0043309	regulation of eosinophil degranulation	8.565904e-3
GO:0021571	rhombomere 5 development	8.589083e-3
GO:0060816	random inactivation of X chromosome	8.620376e-3
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	8.620376e-3
GO:0046670	positive regulation of retinal cell programmed cell death	8.620376e-3
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	8.620376e-3
GO:0032738	positive regulation of interleukin-15 production	8.620376e-3
GO:0009236	cobalamin biosynthetic process	8.620376e-3
GO:0097105	presynaptic membrane assembly	8.639799e-3
GO:0006975	DNA damage induced protein phosphorylation	8.639799e-3
GO:0065002	intracellular protein transmembrane transport	8.726067e-3
GO:0006528	asparagine metabolic process	8.726067e-3
GO:2000543	positive regulation of gastrulation	8.802851e-3
GO:0045719	negative regulation of glycogen biosynthetic process	8.821197e-3
GO:0006654	phosphatidic acid biosynthetic process	8.890479e-3
GO:2000617	positive regulation of histone H3-K9 acetylation	8.926327e-3
GO:0090149	membrane fission involved in mitochondrial fission	8.926327e-3
GO:2000620	positive regulation of histone H4-K16 acetylation	8.926327e-3
GO:0070625	zymogen granule exocytosis	8.926327e-3
GO:0009088	threonine biosynthetic process	8.926327e-3
GO:0070512	positive regulation of histone H4-K20 methylation	8.926327e-3
GO:0003374	dynamin polymerization involved in mitochondrial fission	8.926327e-3
GO:0060391	positive regulation of SMAD protein import into nucleus	9.022656e-3
GO:2000109	regulation of macrophage apoptosis	9.118745e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	9.118745e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	9.118745e-3
GO:0072393	microtubule anchoring at microtubule organizing center	9.186297e-3
GO:0051168	nuclear export	9.232939e-3
GO:0015842	synaptic vesicle amine transport	9.274753e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	9.294604e-3
GO:0001881	receptor recycling	9.570857e-3
GO:0032525	somite rostral/caudal axis specification	9.679237e-3
GO:0046360	2-oxobutyrate biosynthetic process	9.737436e-3
GO:0090234	regulation of kinetochore assembly	9.904530e-3
GO:0090169	regulation of spindle assembly	9.904530e-3
GO:0010107	potassium ion import	9.945369e-3
GO:0002121	inter-male aggressive behavior	9.945369e-3
GO:0006607	NLS-bearing substrate import into nucleus	1.010583e-2
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.017632e-2
GO:0090281	negative regulation of calcium ion import	1.017632e-2
GO:0071584	negative regulation of zinc ion import	1.017632e-2
GO:0035732	nitric oxide storage	1.017632e-2
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	1.017632e-2
GO:0035726	common myeloid progenitor cell proliferation	1.017632e-2
GO:0072111	cell proliferation involved in kidney development	1.018843e-2
GO:0051292	nuclear pore complex assembly	1.037882e-2
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.037882e-2
GO:0002438	acute inflammatory response to antigenic stimulus	1.037882e-2
GO:0072164	mesonephric tubule development	1.039142e-2
GO:0045351	type I interferon biosynthetic process	1.039726e-2
GO:0019048	virus-host interaction	1.049703e-2
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	1.054350e-2
GO:0032066	nucleolus to nucleoplasm transport	1.065861e-2
GO:0048706	embryonic skeletal system development	1.066103e-2
GO:0070934	CRD-mediated mRNA stabilization	1.084142e-2
GO:0006362	transcription elongation from RNA polymerase I promoter	1.095707e-2
GO:0007569	cell aging	1.103812e-2
GO:0042472	inner ear morphogenesis	1.119631e-2
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.124153e-2
GO:0045655	regulation of monocyte differentiation	1.126964e-2
GO:0071480	cellular response to gamma radiation	1.137030e-2
GO:0051865	protein autoubiquitination	1.140830e-2
GO:0006657	CDP-choline pathway	1.149445e-2
GO:0048752	semicircular canal morphogenesis	1.149445e-2
GO:0060045	positive regulation of cardiac muscle cell proliferation	1.161692e-2
GO:0035329	hippo signaling cascade	1.162401e-2
GO:0009264	deoxyribonucleotide catabolic process	1.165332e-2
GO:0031935	regulation of chromatin silencing	1.171060e-2
GO:0010837	regulation of keratinocyte proliferation	1.178049e-2
GO:0090344	negative regulation of cell aging	1.178558e-2
GO:0006273	lagging strand elongation	1.181732e-2
GO:0003062	regulation of heart rate by chemical signal	1.186550e-2
GO:0060596	mammary placode formation	1.224004e-2
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.243515e-2
GO:0046939	nucleotide phosphorylation	1.249966e-2
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	1.263746e-2
GO:0072166	posterior mesonephric tubule development	1.275714e-2
GO:2000466	negative regulation of glycogen (starch) synthase activity	1.275714e-2
GO:0046952	ketone body catabolic process	1.275714e-2
GO:0042572	retinol metabolic process	1.276413e-2
GO:0022613	ribonucleoprotein complex biogenesis	1.283795e-2
GO:0031936	negative regulation of chromatin silencing	1.288019e-2
GO:0046627	negative regulation of insulin receptor signaling pathway	1.290846e-2
GO:0090398	cellular senescence	1.300214e-2
GO:0007344	pronuclear fusion	1.302211e-2
GO:0018027	peptidyl-lysine dimethylation	1.307931e-2
GO:0070647	protein modification by small protein conjugation or removal	1.314361e-2
GO:0033522	histone H2A ubiquitination	1.334446e-2
GO:0007212	dopamine receptor signaling pathway	1.353803e-2
GO:0070106	interleukin-27-mediated signaling pathway	1.354981e-2
GO:0060968	regulation of gene silencing	1.356246e-2
GO:0015919	peroxisomal membrane transport	1.386860e-2
GO:0048291	isotype switching to IgG isotypes	1.386860e-2
GO:0070370	cellular heat acclimation	1.386860e-2
GO:0031591	wybutosine biosynthetic process	1.386860e-2
GO:0002368	B cell cytokine production	1.386860e-2
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.386860e-2
GO:0006393	termination of mitochondrial transcription	1.386860e-2
GO:0033563	dorsal/ventral axon guidance	1.420977e-2
GO:0016241	regulation of macroautophagy	1.420977e-2
GO:0015862	uridine transport	1.420977e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.422621e-2
GO:0007184	SMAD protein import into nucleus	1.435462e-2
GO:0016073	snRNA metabolic process	1.443517e-2
GO:0032226	positive regulation of synaptic transmission, dopaminergic	1.447313e-2
GO:0015908	fatty acid transport	1.448800e-2
GO:0001941	postsynaptic membrane organization	1.461616e-2
GO:0008634	negative regulation of survival gene product expression	1.475369e-2
GO:0035305	negative regulation of dephosphorylation	1.490813e-2
GO:0006783	heme biosynthetic process	1.493236e-2
GO:0070079	histone H4-R3 demethylation	1.534618e-2
GO:0070078	histone H3-R2 demethylation	1.534618e-2
GO:0014816	satellite cell differentiation	1.534618e-2
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.534618e-2
GO:0046620	regulation of organ growth	1.543247e-2
GO:0009067	aspartate family amino acid biosynthetic process	1.545128e-2
GO:0097028	dendritic cell differentiation	1.548401e-2
GO:0035284	brain segmentation	1.552256e-2
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.555426e-2
GO:0048790	maintenance of presynaptic active zone structure	1.593724e-2
GO:2000778	positive regulation of interleukin-6 secretion	1.593724e-2
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.593724e-2
GO:0002118	aggressive behavior	1.605134e-2
GO:0021703	locus ceruleus development	1.611493e-2
GO:0090394	negative regulation of excitatory postsynaptic membrane potential	1.611493e-2
GO:0010933	positive regulation of macrophage tolerance induction	1.611493e-2
GO:0018283	iron incorporation into metallo-sulfur cluster	1.615327e-2
GO:0032006	regulation of TOR signaling cascade	1.617519e-2
GO:0009110	vitamin biosynthetic process	1.623451e-2
GO:0070367	negative regulation of hepatocyte differentiation	1.623615e-2
GO:0043017	positive regulation of lymphotoxin A biosynthetic process	1.623615e-2
GO:0000917	barrier septum formation	1.623615e-2
GO:0009231	riboflavin biosynthetic process	1.623615e-2
GO:0060706	cell differentiation involved in embryonic placenta development	1.636732e-2
GO:0034047	regulation of protein phosphatase type 2A activity	1.641253e-2
GO:0014051	gamma-aminobutyric acid secretion	1.641253e-2
GO:0014912	negative regulation of smooth muscle cell migration	1.642963e-2
GO:0040015	negative regulation of multicellular organism growth	1.644219e-2
GO:0035545	determination of left/right asymmetry in nervous system	1.664156e-2
GO:0048560	establishment of anatomical structure orientation	1.664860e-2
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1.664860e-2
GO:0043089	positive regulation of Cdc42 GTPase activity	1.672514e-2
GO:0042473	outer ear morphogenesis	1.672514e-2
GO:0002726	positive regulation of T cell cytokine production	1.693877e-2
GO:0006261	DNA-dependent DNA replication	1.701409e-2
GO:0015879	carnitine transport	1.725460e-2
GO:0070483	detection of hypoxia	1.770774e-2
GO:0019276	UDP-N-acetylgalactosamine metabolic process	1.770774e-2
GO:0090239	regulation of histone H4 acetylation	1.772345e-2
GO:0021569	rhombomere 3 development	1.772345e-2
GO:0006390	transcription from mitochondrial promoter	1.772345e-2
GO:0055094	response to lipoprotein stimulus	1.812011e-2
GO:0060056	mammary gland involution	1.827589e-2
GO:0035456	response to interferon-beta	1.840048e-2
GO:0031558	induction of apoptosis in response to chemical stimulus	1.849991e-2
GO:0019047	provirus integration	1.850724e-2
GO:0045820	negative regulation of glycolysis	1.860369e-2
GO:0006513	protein monoubiquitination	1.877094e-2
GO:0043380	regulation of memory T cell differentiation	1.886582e-2
GO:0042994	cytoplasmic sequestering of transcription factor	1.910057e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010467	gene expression	4.345360e-10
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.471776e-8
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	2.413778e-7
GO:0016070	RNA metabolic process	4.525302e-7
GO:0090304	nucleic acid metabolic process	5.853740e-7
GO:0031442	positive regulation of mRNA 3'-end processing	6.778332e-7
GO:0061014	positive regulation of mRNA catabolic process	6.976561e-7
GO:0031440	regulation of mRNA 3'-end processing	2.145160e-6
GO:0051930	regulation of sensory perception of pain	2.486238e-6
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	3.015661e-6
GO:0018192	enzyme active site formation via L-cysteine persulfide	3.434532e-6
GO:0042474	middle ear morphogenesis	5.294499e-6
GO:0043461	proton-transporting ATP synthase complex assembly	6.971949e-6
GO:0070845	polyubiquitinated misfolded protein transport	9.304275e-6
GO:0071169	establishment of protein localization to chromatin	1.046227e-5
GO:0006366	transcription from RNA polymerase II promoter	1.076261e-5
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.387969e-5
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.487842e-5
GO:0006352	transcription initiation, DNA-dependent	1.677700e-5
GO:0006999	nuclear pore organization	2.024310e-5
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	2.272696e-5
GO:0051973	positive regulation of telomerase activity	2.929753e-5
GO:0006396	RNA processing	3.400006e-5
GO:0048368	lateral mesoderm development	4.035305e-5
GO:0014826	vein smooth muscle contraction	4.456000e-5
GO:0051865	protein autoubiquitination	4.633726e-5
GO:0021528	commissural neuron differentiation in spinal cord	5.384614e-5
GO:0065004	protein-DNA complex assembly	5.467220e-5
GO:0042254	ribosome biogenesis	6.128635e-5
GO:0097152	mesenchymal cell apoptosis	6.264094e-5
GO:0090042	tubulin deacetylation	6.946900e-5
GO:0033314	mitotic cell cycle DNA replication checkpoint	6.946900e-5
GO:0070846	Hsp90 deacetylation	6.946900e-5
GO:0001759	organ induction	7.362142e-5
GO:0043488	regulation of mRNA stability	7.948156e-5
GO:0006403	RNA localization	8.986439e-5
GO:0007049	cell cycle	9.432832e-5
GO:2001037	positive regulation of tongue muscle cell differentiation	9.719644e-5
GO:0060264	regulation of respiratory burst involved in inflammatory response	1.002950e-4
GO:0085020	protein K6-linked ubiquitination	1.002950e-4
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	1.006135e-4
GO:0034260	negative regulation of GTPase activity	1.049583e-4
GO:0043487	regulation of RNA stability	1.122041e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.165257e-4
GO:0034645	cellular macromolecule biosynthetic process	1.233018e-4
GO:0006412	translation	1.326071e-4
GO:0050685	positive regulation of mRNA processing	1.353833e-4
GO:0006351	transcription, DNA-dependent	1.589776e-4
GO:0034660	ncRNA metabolic process	1.650136e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	1.651025e-4
GO:0060458	right lung development	1.657653e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	1.697040e-4
GO:0032774	RNA biosynthetic process	1.846176e-4
GO:0035633	maintenance of blood-brain barrier	1.926136e-4
GO:0007270	neuron-neuron synaptic transmission	2.021408e-4
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	2.087854e-4
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	2.208776e-4
GO:0050658	RNA transport	2.478848e-4
GO:0044314	protein K27-linked ubiquitination	2.596373e-4
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	2.630917e-4
GO:0001881	receptor recycling	2.630917e-4
GO:0070166	enamel mineralization	2.736724e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.771198e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.771198e-4
GO:0032707	negative regulation of interleukin-23 production	2.771198e-4
GO:0045362	positive regulation of interleukin-1 biosynthetic process	2.771198e-4
GO:0060012	synaptic transmission, glycinergic	3.038587e-4
GO:0032203	telomere formation via telomerase	3.038587e-4
GO:0034661	ncRNA catabolic process	3.039543e-4
GO:0044260	cellular macromolecule metabolic process	3.124637e-4
GO:0046986	negative regulation of hemoglobin biosynthetic process	3.141494e-4
GO:0060710	chorio-allantoic fusion	3.435332e-4
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.476575e-4
GO:0019363	pyridine nucleotide biosynthetic process	3.494710e-4
GO:0061304	retinal blood vessel morphogenesis	3.736120e-4
GO:0035269	protein O-linked mannosylation	3.861109e-4
GO:0009059	macromolecule biosynthetic process	3.941072e-4
GO:0048378	regulation of lateral mesodermal cell fate specification	4.056782e-4
GO:0006383	transcription from RNA polymerase III promoter	4.056782e-4
GO:2001076	positive regulation of metanephric ureteric bud development	4.340044e-4
GO:0007356	thorax and anterior abdomen determination	4.340044e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.340044e-4
GO:0042473	outer ear morphogenesis	4.684311e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	4.729204e-4
GO:2000195	negative regulation of female gonad development	4.931990e-4
GO:0071843	cellular component biogenesis at cellular level	5.283828e-4
GO:0033239	negative regulation of cellular amine metabolic process	5.312900e-4
GO:0006207	'de novo' pyrimidine base biosynthetic process	5.312900e-4
GO:0045109	intermediate filament organization	5.723599e-4
GO:0060914	heart formation	5.806496e-4
GO:0071824	protein-DNA complex subunit organization	5.860721e-4
GO:0071157	negative regulation of cell cycle arrest	5.911443e-4
GO:0060013	righting reflex	6.237966e-4
GO:2000778	positive regulation of interleukin-6 secretion	6.283280e-4
GO:0061301	cerebellum vasculature morphogenesis	6.283280e-4
GO:0035306	positive regulation of dephosphorylation	6.779939e-4
GO:0060446	branching involved in open tracheal system development	7.192954e-4
GO:0090131	mesenchyme migration	7.192954e-4
GO:2000001	regulation of DNA damage checkpoint	7.192954e-4
GO:0060461	right lung morphogenesis	7.192954e-4
GO:0014822	detection of wounding	7.192954e-4
GO:0048371	lateral mesodermal cell differentiation	7.192954e-4
GO:0048613	embryonic ectodermal digestive tract morphogenesis	7.192954e-4
GO:0030970	retrograde protein transport, ER to cytosol	7.515738e-4
GO:0014041	regulation of neuron maturation	7.660899e-4
GO:0006139	nucleobase-containing compound metabolic process	7.792290e-4
GO:0035195	gene silencing by miRNA	9.576040e-4
GO:0072095	regulation of branch elongation involved in ureteric bud branching	9.686364e-4
GO:0061013	regulation of mRNA catabolic process	9.777292e-4
GO:0042363	fat-soluble vitamin catabolic process	9.993739e-4
GO:0038007	netrin-activated signaling pathway	9.993739e-4
GO:0008611	ether lipid biosynthetic process	1.019564e-3
GO:0000238	zygotene	1.019564e-3
GO:0035850	epithelial cell differentiation involved in kidney development	1.021274e-3
GO:0043687	post-translational protein modification	1.023512e-3
GO:0072355	histone H3-T3 phosphorylation	1.048190e-3
GO:0050928	negative regulation of positive chemotaxis	1.048190e-3
GO:0042228	interleukin-8 biosynthetic process	1.048190e-3
GO:0071168	protein localization to chromatin	1.097200e-3
GO:0048143	astrocyte activation	1.131363e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.152779e-3
GO:0035307	positive regulation of protein dephosphorylation	1.159085e-3
GO:0022613	ribonucleoprotein complex biogenesis	1.169613e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	1.182033e-3
GO:0035645	enteric smooth muscle cell differentiation	1.182033e-3
GO:0007497	posterior midgut development	1.182033e-3
GO:0010312	detoxification of zinc ion	1.188532e-3
GO:0016072	rRNA metabolic process	1.236643e-3
GO:0034441	plasma lipoprotein particle oxidation	1.240056e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.251267e-3
GO:0048703	embryonic viscerocranium morphogenesis	1.265001e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.271142e-3
GO:0007051	spindle organization	1.296042e-3
GO:0071498	cellular response to fluid shear stress	1.322607e-3
GO:2000194	regulation of female gonad development	1.358756e-3
GO:0046604	positive regulation of mitotic centrosome separation	1.393488e-3
GO:0051340	regulation of ligase activity	1.418541e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	1.426150e-3
GO:0080164	regulation of nitric oxide metabolic process	1.426150e-3
GO:0051252	regulation of RNA metabolic process	1.465497e-3
GO:0006355	regulation of transcription, DNA-dependent	1.532011e-3
GO:0072160	nephron tubule epithelial cell differentiation	1.544397e-3
GO:2001013	epithelial cell proliferation involve in renal tubule morphogenesis	1.544397e-3
GO:0015870	acetylcholine transport	1.575303e-3
GO:0034447	very-low-density lipoprotein particle clearance	1.585088e-3
GO:0010044	response to aluminum ion	1.637212e-3
GO:0003156	regulation of organ formation	1.664275e-3
GO:0034470	ncRNA processing	1.771984e-3
GO:0034653	retinoic acid catabolic process	1.809363e-3
GO:0006363	termination of RNA polymerase I transcription	1.809363e-3
GO:0008380	RNA splicing	1.818136e-3
GO:0060696	regulation of phospholipid catabolic process	1.889158e-3
GO:0014002	astrocyte development	1.938366e-3
GO:0033037	polysaccharide localization	1.952075e-3
GO:0090310	negative regulation of methylation-dependent chromatin silencing	1.961616e-3
GO:0046755	non-lytic virus budding	1.973837e-3
GO:0015931	nucleobase-containing compound transport	2.030928e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	2.068530e-3
GO:0000415	negative regulation of histone H3-K36 methylation	2.091256e-3
GO:0090103	cochlea morphogenesis	2.106864e-3
GO:0035194	posttranscriptional gene silencing by RNA	2.263809e-3
GO:0006901	vesicle coating	2.318155e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	2.373180e-3
GO:0016071	mRNA metabolic process	2.375433e-3
GO:0014043	negative regulation of neuron maturation	2.467330e-3
GO:0050779	RNA destabilization	2.514454e-3
GO:0034720	histone H3-K4 demethylation	2.514454e-3
GO:0070625	zymogen granule exocytosis	2.625297e-3
GO:0071594	thymocyte aggregation	2.625297e-3
GO:0010933	positive regulation of macrophage tolerance induction	2.625297e-3
GO:0061298	retina vasculature development in camera-type eye	2.628076e-3
GO:0032872	regulation of stress-activated MAPK cascade	2.664036e-3
GO:0051451	myoblast migration	2.685479e-3
GO:0070830	tight junction assembly	2.710394e-3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2.714386e-3
GO:0002438	acute inflammatory response to antigenic stimulus	2.720626e-3
GO:0048857	neural nucleus development	2.735065e-3
GO:0048680	positive regulation of axon regeneration	2.834251e-3
GO:0042659	regulation of cell fate specification	2.835757e-3
GO:0032835	glomerulus development	2.862742e-3
GO:0051583	dopamine uptake	2.920810e-3
GO:0002098	tRNA wobble uridine modification	2.920810e-3
GO:0015862	uridine transport	2.990197e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	3.141109e-3
GO:0060124	positive regulation of growth hormone secretion	3.256192e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	3.256192e-3
GO:2000297	negative regulation of synapse maturation	3.265764e-3
GO:0043153	entrainment of circadian clock by photoperiod	3.265764e-3
GO:0043508	negative regulation of JUN kinase activity	3.278836e-3
GO:0046607	positive regulation of centrosome cycle	3.286307e-3
GO:0000917	barrier septum formation	3.286307e-3
GO:0007052	mitotic spindle organization	3.291872e-3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	3.298889e-3
GO:0006364	rRNA processing	3.345723e-3
GO:0032780	negative regulation of ATPase activity	3.376155e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	3.465106e-3
GO:0009107	lipoate biosynthetic process	3.511561e-3
GO:0060081	membrane hyperpolarization	3.529824e-3
GO:0048484	enteric nervous system development	3.587496e-3
GO:0000070	mitotic sister chromatid segregation	3.818416e-3
GO:0016032	viral reproduction	3.856009e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	3.869314e-3
GO:0003333	amino acid transmembrane transport	3.870922e-3
GO:0051569	regulation of histone H3-K4 methylation	3.881848e-3
GO:0048268	clathrin coat assembly	3.920227e-3
GO:0009108	coenzyme biosynthetic process	3.960195e-3
GO:0021571	rhombomere 5 development	4.007533e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	4.049429e-3
GO:0043587	tongue morphogenesis	4.067245e-3
GO:0006427	histidyl-tRNA aminoacylation	4.091836e-3
GO:0032383	regulation of intracellular cholesterol transport	4.091836e-3
GO:0051355	proprioception involved in equilibrioception	4.091836e-3
GO:0019047	provirus integration	4.091836e-3
GO:0042661	regulation of mesodermal cell fate specification	4.233016e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	4.403366e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	4.524272e-3
GO:0045599	negative regulation of fat cell differentiation	4.558721e-3
GO:0060459	left lung development	4.567200e-3
GO:0060075	regulation of resting membrane potential	4.570547e-3
GO:2000020	positive regulation of male gonad development	4.581582e-3
GO:0000279	M phase	4.621187e-3
GO:0032728	positive regulation of interferon-beta production	4.637573e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	4.692072e-3
GO:0006474	N-terminal protein amino acid acetylation	4.844811e-3
GO:0046501	protoporphyrinogen IX metabolic process	4.953854e-3
GO:0042660	positive regulation of cell fate specification	4.953854e-3
GO:0000076	DNA replication checkpoint	4.953854e-3
GO:0009648	photoperiodism	4.953854e-3
GO:0070170	regulation of tooth mineralization	5.247466e-3
GO:0000819	sister chromatid segregation	5.353538e-3
GO:0006900	membrane budding	5.387458e-3
GO:0034227	tRNA thio-modification	5.457495e-3
GO:0006424	glutamyl-tRNA aminoacylation	5.457560e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	5.457560e-3
GO:0006422	aspartyl-tRNA aminoacylation	5.457560e-3
GO:0051775	response to redox state	5.484299e-3
GO:0097029	mature dendritic cell differentiation	5.484299e-3
GO:0045919	positive regulation of cytolysis	5.484299e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	5.484699e-3
GO:0060923	cardiac muscle cell fate commitment	5.552009e-3
GO:2000380	regulation of mesoderm development	5.594259e-3
GO:0031054	pre-miRNA processing	5.603379e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	5.645122e-3
GO:2000272	negative regulation of receptor activity	5.652886e-3
GO:0048255	mRNA stabilization	5.912772e-3
GO:0046452	dihydrofolate metabolic process	6.022269e-3
GO:0002418	immune response to tumor cell	6.022269e-3
GO:0030150	protein import into mitochondrial matrix	6.022269e-3
GO:0003139	secondary heart field specification	6.066825e-3
GO:0042136	neurotransmitter biosynthetic process	6.074940e-3
GO:0051028	mRNA transport	6.086200e-3
GO:0010587	miRNA catabolic process	6.318689e-3
GO:0051572	negative regulation of histone H3-K4 methylation	6.318689e-3
GO:0046504	glycerol ether biosynthetic process	6.363835e-3
GO:0051145	smooth muscle cell differentiation	6.409176e-3
GO:0009649	entrainment of circadian clock	6.454074e-3
GO:0043555	regulation of translation in response to stress	6.527832e-3
GO:0048701	embryonic cranial skeleton morphogenesis	6.548884e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	6.646579e-3
GO:0016601	Rac protein signal transduction	6.841597e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	7.003403e-3
GO:0000729	DNA double-strand break processing	7.255575e-3
GO:0009051	pentose-phosphate shunt, oxidative branch	7.255575e-3
GO:0000414	regulation of histone H3-K36 methylation	7.255575e-3
GO:0006105	succinate metabolic process	7.337548e-3
GO:0035364	thymine transport	7.339173e-3
GO:0015854	guanine transport	7.339173e-3
GO:0071279	cellular response to cobalt ion	7.339173e-3
GO:0035344	hypoxanthine transport	7.339173e-3
GO:0010637	negative regulation of mitochondrial fusion	7.339173e-3
GO:0015853	adenine transport	7.339173e-3
GO:0006348	chromatin silencing at telomere	7.339173e-3
GO:0032465	regulation of cytokinesis	7.420232e-3
GO:0032530	regulation of microvillus organization	7.509532e-3
GO:0035802	adrenal cortex formation	7.509532e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	7.548274e-3
GO:0021904	dorsal/ventral neural tube patterning	7.571442e-3
GO:0021954	central nervous system neuron development	7.609622e-3
GO:0021516	dorsal spinal cord development	7.752255e-3
GO:0051795	positive regulation of catagen	7.806480e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	7.806480e-3
GO:0032497	detection of lipopolysaccharide	7.806480e-3
GO:0006268	DNA unwinding involved in replication	7.878468e-3
GO:0060561	apoptosis involved in morphogenesis	7.965869e-3
GO:0008634	negative regulation of survival gene product expression	8.003072e-3
GO:0016925	protein sumoylation	8.033446e-3
GO:0070171	negative regulation of tooth mineralization	8.230403e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	8.311764e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	8.514229e-3
GO:0044249	cellular biosynthetic process	8.582729e-3
GO:0034508	centromere complex assembly	8.748518e-3
GO:0019348	dolichol metabolic process	8.816521e-3
GO:0072193	ureter smooth muscle cell differentiation	9.066044e-3
GO:0021526	medial motor column neuron differentiation	9.161999e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	9.161999e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	9.161999e-3
GO:0046836	glycolipid transport	9.161999e-3
GO:0019428	allantoin biosynthetic process	9.164578e-3
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	9.339395e-3
GO:0032288	myelin assembly	9.430350e-3
GO:0060023	soft palate development	9.446374e-3
GO:0031109	microtubule polymerization or depolymerization	9.446374e-3
GO:0022403	cell cycle phase	9.476344e-3
GO:0035089	establishment of apical/basal cell polarity	9.547822e-3
GO:2000178	negative regulation of neural precursor cell proliferation	9.615586e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	9.651579e-3
GO:0048352	paraxial mesoderm structural organization	9.887843e-3
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	9.887843e-3
GO:0021998	neural plate mediolateral regionalization	9.887843e-3
GO:0021587	cerebellum morphogenesis	9.968057e-3
GO:0048818	positive regulation of hair follicle maturation	1.000009e-2
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	1.009126e-2
GO:0002430	complement receptor mediated signaling pathway	1.009126e-2
GO:0016068	type I hypersensitivity	1.009126e-2
GO:0045081	negative regulation of interleukin-10 biosynthetic process	1.012009e-2
GO:0032055	negative regulation of translation in response to stress	1.012009e-2
GO:0046984	regulation of hemoglobin biosynthetic process	1.030227e-2
GO:0032534	regulation of microvillus assembly	1.030227e-2
GO:0061028	establishment of endothelial barrier	1.047497e-2
GO:0046112	nucleobase biosynthetic process	1.100342e-2
GO:0007099	centriole replication	1.117666e-2
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.126778e-2
GO:0070918	production of small RNA involved in gene silencing by RNA	1.131996e-2
GO:0000080	G1 phase of mitotic cell cycle	1.131996e-2
GO:0010889	regulation of sequestering of triglyceride	1.131996e-2
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.145837e-2
GO:0033084	regulation of immature T cell proliferation in thymus	1.146549e-2
GO:0070050	neuron homeostasis	1.146549e-2
GO:0046668	regulation of retinal cell programmed cell death	1.149067e-2
GO:0042089	cytokine biosynthetic process	1.182139e-2
GO:0006397	mRNA processing	1.184363e-2
GO:0070498	interleukin-1-mediated signaling pathway	1.194088e-2
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.209705e-2
GO:0007131	reciprocal meiotic recombination	1.210476e-2
GO:0072298	regulation of metanephric glomerulus development	1.224015e-2
GO:0060711	labyrinthine layer development	1.258771e-2
GO:0072075	metanephric mesenchyme development	1.259448e-2
GO:0021559	trigeminal nerve development	1.279989e-2
GO:0031123	RNA 3'-end processing	1.300853e-2
GO:2000018	regulation of male gonad development	1.305195e-2
GO:0072125	negative regulation of glomerular mesangial cell proliferation	1.312264e-2
GO:0034261	negative regulation of Ras GTPase activity	1.312264e-2
GO:0072278	metanephric comma-shaped body morphogenesis	1.338028e-2
GO:0072284	metanephric S-shaped body morphogenesis	1.338028e-2
GO:0035426	extracellular matrix-cell signaling	1.338028e-2
GO:0060578	superior vena cava morphogenesis	1.371951e-2
GO:0071034	CUT catabolic process	1.371951e-2
GO:0051382	kinetochore assembly	1.371951e-2
GO:0090141	positive regulation of mitochondrial fission	1.371951e-2
GO:0042373	vitamin K metabolic process	1.371951e-2
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	1.371951e-2
GO:0031508	centromeric heterochromatin formation	1.371951e-2
GO:2000987	positive regulation of behavioral fear response	1.373670e-2
GO:0060025	regulation of synaptic activity	1.373670e-2
GO:0003185	sinoatrial valve morphogenesis	1.373670e-2
GO:0035984	cellular response to trichostatin A	1.373670e-2
GO:0003138	primary heart field specification	1.373670e-2
GO:0060438	trachea development	1.374229e-2
GO:0060911	cardiac cell fate commitment	1.376255e-2
GO:0072107	positive regulation of ureteric bud formation	1.376467e-2
GO:0060020	Bergmann glial cell differentiation	1.378595e-2
GO:0043524	negative regulation of neuron apoptosis	1.386425e-2
GO:0007030	Golgi organization	1.406453e-2
GO:0001885	endothelial cell development	1.414411e-2
GO:0021527	spinal cord association neuron differentiation	1.414541e-2
GO:0061088	regulation of sequestering of zinc ion	1.422986e-2
GO:0000395	nuclear mRNA 5'-splice site recognition	1.422986e-2
GO:0001812	positive regulation of type I hypersensitivity	1.422986e-2
GO:0060021	palate development	1.436488e-2
GO:0045039	protein import into mitochondrial inner membrane	1.444240e-2
GO:0043297	apical junction assembly	1.453780e-2
GO:0072215	regulation of metanephros development	1.500866e-2
GO:0032490	detection of molecule of bacterial origin	1.522832e-2
GO:0018279	protein N-linked glycosylation via asparagine	1.522832e-2
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.527983e-2
GO:2000429	negative regulation of neutrophil aggregation	1.527983e-2
GO:2000469	negative regulation of peroxidase activity	1.527983e-2
GO:0071352	cellular response to interleukin-2	1.527983e-2
GO:0042942	D-serine transport	1.527983e-2
GO:0002357	defense response to tumor cell	1.527983e-2
GO:0065002	intracellular protein transmembrane transport	1.527983e-2
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	1.527983e-2
GO:0035726	common myeloid progenitor cell proliferation	1.527983e-2
GO:0051351	positive regulation of ligase activity	1.531125e-2
GO:0008063	Toll signaling pathway	1.546709e-2
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	1.546709e-2
GO:0007019	microtubule depolymerization	1.546709e-2
GO:0002693	positive regulation of cellular extravasation	1.546709e-2
GO:0043586	tongue development	1.569966e-2
GO:0051095	regulation of helicase activity	1.581851e-2
GO:0006538	glutamate catabolic process	1.581851e-2
GO:0048102	autophagic cell death	1.581851e-2
GO:0046580	negative regulation of Ras protein signal transduction	1.587296e-2
GO:0060729	intestinal epithelial structure maintenance	1.601895e-2
GO:0015864	pyrimidine nucleoside transport	1.601895e-2
GO:0021800	cerebral cortex tangential migration	1.610452e-2
GO:0021569	rhombomere 3 development	1.620920e-2
GO:0010556	regulation of macromolecule biosynthetic process	1.622910e-2
GO:0051972	regulation of telomerase activity	1.655530e-2
GO:0051383	kinetochore organization	1.680006e-2
GO:0006668	sphinganine-1-phosphate metabolic process	1.680006e-2
GO:0060265	positive regulation of respiratory burst involved in inflammatory response	1.689621e-2
GO:0050916	sensory perception of sweet taste	1.689621e-2
GO:0002232	leukocyte chemotaxis involved in inflammatory response	1.689621e-2
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.689621e-2
GO:0072074	kidney mesenchyme development	1.724867e-2
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.733868e-2
GO:0014057	positive regulation of acetylcholine secretion	1.733868e-2
GO:0010936	negative regulation of macrophage cytokine production	1.738297e-2
GO:0090030	regulation of steroid hormone biosynthetic process	1.753873e-2
GO:0090073	positive regulation of protein homodimerization activity	1.768333e-2
GO:0006266	DNA ligation	1.768333e-2
GO:0032677	regulation of interleukin-8 production	1.835208e-2
GO:0035993	deltoid tuberosity development	1.838851e-2
GO:0009880	embryonic pattern specification	1.855682e-2
GO:0072102	glomerulus morphogenesis	1.865149e-2
GO:0043558	regulation of translational initiation in response to stress	1.917434e-2
GO:0072060	outer medullary collecting duct development	1.917434e-2
GO:0072061	inner medullary collecting duct development	1.917434e-2
GO:0021644	vagus nerve morphogenesis	1.917434e-2
GO:0019230	proprioception	1.917434e-2
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.917434e-2
GO:0034393	positive regulation of smooth muscle cell apoptosis	1.926112e-2
GO:0042984	regulation of amyloid precursor protein biosynthetic process	1.956132e-2
GO:0090140	regulation of mitochondrial fission	1.972821e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	1.972821e-2
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.972821e-2
GO:0070071	proton-transporting two-sector ATPase complex assembly	1.976740e-2
GO:0061056	sclerotome development	1.982650e-2
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1.982650e-2
GO:0031573	intra-S DNA damage checkpoint	1.982650e-2
GO:0060017	parathyroid gland development	1.990151e-2
GO:0042471	ear morphogenesis	1.993611e-2
GO:0051301	cell division	2.013004e-2
GO:0033081	regulation of T cell differentiation in thymus	2.016023e-2
GO:0010453	regulation of cell fate commitment	2.036403e-2
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.063580e-2
GO:0010468	regulation of gene expression	2.064821e-2
GO:0050847	progesterone receptor signaling pathway	2.091642e-2
GO:0072166	posterior mesonephric tubule development	2.094546e-2
GO:0046340	diacylglycerol catabolic process	2.094546e-2
GO:0032508	DNA duplex unwinding	2.101526e-2
GO:0034446	substrate adhesion-dependent cell spreading	2.126679e-2
GO:0046874	quinolinate metabolic process	2.157315e-2
GO:0007043	cell-cell junction assembly	2.197525e-2
GO:0033083	regulation of immature T cell proliferation	2.210535e-2
GO:0046931	pore complex assembly	2.222047e-2
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.222047e-2
GO:0043583	ear development	2.235513e-2
GO:0070076	histone lysine demethylation	2.247945e-2
GO:0032202	telomere assembly	2.293579e-2
GO:0051292	nuclear pore complex assembly	2.293579e-2
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	2.293579e-2
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	2.295903e-2
GO:0090245	axis elongation involved in somitogenesis	2.295903e-2
GO:0021570	rhombomere 4 development	2.295903e-2
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	2.295903e-2
GO:0000492	box C/D snoRNP assembly	2.295903e-2
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.322287e-2
GO:0042147	retrograde transport, endosome to Golgi	2.323992e-2
GO:2000108	positive regulation of leukocyte apoptosis	2.349085e-2
GO:0007619	courtship behavior	2.374616e-2
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	2.374616e-2
GO:0021884	forebrain neuron development	2.379457e-2
GO:0006415	translational termination	2.393886e-2
GO:0007076	mitotic chromosome condensation	2.425642e-2
GO:0016486	peptide hormone processing	2.485019e-2
GO:0048562	embryonic organ morphogenesis	2.493018e-2
GO:0072164	mesonephric tubule development	2.504636e-2
GO:0042941	D-alanine transport	2.507824e-2
GO:0009443	pyridoxal 5'-phosphate salvage	2.507824e-2
GO:0060033	anatomical structure regression	2.510824e-2
GO:0017145	stem cell division	2.547376e-2
GO:0006405	RNA export from nucleus	2.618547e-2
GO:0050823	peptide antigen stabilization	2.629511e-2
GO:0071786	endoplasmic reticulum tubular network organization	2.629511e-2
GO:0045626	negative regulation of T-helper 1 cell differentiation	2.629511e-2
GO:0032342	aldosterone biosynthetic process	2.629511e-2
GO:0002537	nitric oxide production involved in inflammatory response	2.629511e-2
GO:0032057	negative regulation of translational initiation in response to stress	2.629511e-2
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.629511e-2
GO:0014033	neural crest cell differentiation	2.634964e-2
GO:0045616	regulation of keratinocyte differentiation	2.651889e-2
GO:0006334	nucleosome assembly	2.674185e-2
GO:0021508	floor plate formation	2.739341e-2
GO:0006540	glutamate decarboxylation to succinate	2.739341e-2
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.739341e-2
GO:0050931	pigment cell differentiation	2.748920e-2
GO:0002483	antigen processing and presentation of endogenous peptide antigen	2.760713e-2
GO:0032392	DNA geometric change	2.786508e-2
GO:0010224	response to UV-B	2.831589e-2
GO:0015920	lipopolysaccharide transport	2.863517e-2
GO:0010661	positive regulation of muscle cell apoptosis	2.878413e-2
GO:0032446	protein modification by small protein conjugation	2.880592e-2
GO:0007288	sperm axoneme assembly	2.886148e-2
GO:0007032	endosome organization	2.888525e-2
GO:0022402	cell cycle process	2.889733e-2
GO:0035249	synaptic transmission, glutamatergic	2.895224e-2
GO:0010870	positive regulation of receptor biosynthetic process	2.895282e-2
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	2.895282e-2