Novel motif:2

name:	motif2_GCTGGAGG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	8.290525e-14
GO:0046628	positive regulation of insulin receptor signaling pathway	4.182512e-12
GO:0060033	anatomical structure regression	2.589211e-11
GO:0010984	regulation of lipoprotein particle clearance	4.355080e-11
GO:0060351	cartilage development involved in endochondral bone morphogenesis	6.285619e-11
GO:0035814	negative regulation of renal sodium excretion	6.291177e-11
GO:0010625	positive regulation of Schwann cell proliferation	7.766284e-11
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	4.623185e-10
GO:0050902	leukocyte adhesive activation	4.623185e-10
GO:2000467	positive regulation of glycogen (starch) synthase activity	4.722854e-10
GO:2000465	regulation of glycogen (starch) synthase activity	1.086347e-9
GO:0008078	mesodermal cell migration	2.695714e-9
GO:0035104	positive regulation of transcription via sterol regulatory element binding	5.564215e-9
GO:0010624	regulation of Schwann cell proliferation	8.337830e-9
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	9.835837e-9
GO:0043491	protein kinase B signaling cascade	1.826353e-8
GO:0003009	skeletal muscle contraction	2.279822e-8
GO:0019884	antigen processing and presentation of exogenous antigen	4.832481e-8
GO:0090031	positive regulation of steroid hormone biosynthetic process	5.541944e-8
GO:0045415	negative regulation of interleukin-8 biosynthetic process	7.381499e-8
GO:0032933	SREBP-mediated signaling pathway	7.480128e-8
GO:0006884	cell volume homeostasis	7.946269e-8
GO:0010985	negative regulation of lipoprotein particle clearance	8.136397e-8
GO:0034505	tooth mineralization	1.049544e-7
GO:0071460	cellular response to cell-matrix adhesion	1.147274e-7
GO:0043206	fibril organization	1.245255e-7
GO:0007522	visceral muscle development	1.854908e-7
GO:0046626	regulation of insulin receptor signaling pathway	2.495430e-7
GO:0019048	virus-host interaction	3.268683e-7
GO:0060251	regulation of glial cell proliferation	3.724807e-7
GO:0031444	slow-twitch skeletal muscle fiber contraction	3.789286e-7
GO:0032964	collagen biosynthetic process	4.188880e-7
GO:0002268	follicular dendritic cell differentiation	5.139985e-7
GO:0042074	cell migration involved in gastrulation	5.302732e-7
GO:0006349	regulation of gene expression by genetic imprinting	5.454143e-7
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	5.592006e-7
GO:0002478	antigen processing and presentation of exogenous peptide antigen	8.289140e-7
GO:0040040	thermosensory behavior	8.586765e-7
GO:0003062	regulation of heart rate by chemical signal	1.089680e-6
GO:0010821	regulation of mitochondrion organization	1.194993e-6
GO:0050779	RNA destabilization	1.198558e-6
GO:0001880	Mullerian duct regression	1.334187e-6
GO:0006544	glycine metabolic process	1.373367e-6
GO:0060349	bone morphogenesis	1.440675e-6
GO:0045908	negative regulation of vasodilation	1.442388e-6
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.451250e-6
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.611889e-6
GO:0006706	steroid catabolic process	1.979142e-6
GO:0007509	mesoderm migration involved in gastrulation	2.171464e-6
GO:0033209	tumor necrosis factor-mediated signaling pathway	2.398097e-6
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	2.466475e-6
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	2.716998e-6
GO:0009155	purine deoxyribonucleotide catabolic process	2.806131e-6
GO:0030225	macrophage differentiation	2.993157e-6
GO:0002315	marginal zone B cell differentiation	3.976414e-6
GO:0045064	T-helper 2 cell differentiation	3.976414e-6
GO:0006261	DNA-dependent DNA replication	4.011697e-6
GO:0060348	bone development	4.087904e-6
GO:0045109	intermediate filament organization	4.590602e-6
GO:0010982	regulation of high-density lipoprotein particle clearance	5.778834e-6
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	6.380024e-6
GO:0002906	negative regulation of mature B cell apoptosis	6.380024e-6
GO:0006853	carnitine shuttle	6.500280e-6
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	6.669172e-6
GO:0045725	positive regulation of glycogen biosynthetic process	7.762429e-6
GO:0046339	diacylglycerol metabolic process	7.958857e-6
GO:0015816	glycine transport	8.822820e-6
GO:0051561	elevation of mitochondrial calcium ion concentration	9.217380e-6
GO:0043542	endothelial cell migration	9.757247e-6
GO:0002886	regulation of myeloid leukocyte mediated immunity	9.984127e-6
GO:0046314	phosphocreatine biosynthetic process	1.045866e-5
GO:0030198	extracellular matrix organization	1.147761e-5
GO:0030851	granulocyte differentiation	1.262099e-5
GO:0006707	cholesterol catabolic process	1.270143e-5
GO:0090311	regulation of protein deacetylation	1.304156e-5
GO:0035811	negative regulation of urine volume	1.314227e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.373238e-5
GO:0031063	regulation of histone deacetylation	1.440046e-5
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.448955e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.610569e-5
GO:0048548	regulation of pinocytosis	1.629265e-5
GO:0051085	chaperone mediated protein folding requiring cofactor	1.631323e-5
GO:0034224	cellular response to zinc ion starvation	1.663944e-5
GO:0060669	embryonic placenta morphogenesis	1.706800e-5
GO:0060350	endochondral bone morphogenesis	1.767654e-5
GO:0060252	positive regulation of glial cell proliferation	1.770258e-5
GO:0035094	response to nicotine	1.775822e-5
GO:0030046	parallel actin filament bundle assembly	1.793640e-5
GO:0045906	negative regulation of vasoconstriction	1.849835e-5
GO:0044062	regulation of excretion	1.907579e-5
GO:0043462	regulation of ATPase activity	1.937959e-5
GO:2000251	positive regulation of actin cytoskeleton reorganization	1.945276e-5
GO:0044236	multicellular organismal metabolic process	2.120026e-5
GO:0019087	transformation of host cell by virus	2.135310e-5
GO:0090199	regulation of release of cytochrome c from mitochondria	2.143177e-5
GO:0033505	floor plate morphogenesis	2.228478e-5
GO:0022038	corpus callosum development	2.355615e-5
GO:0018205	peptidyl-lysine modification	2.441273e-5
GO:0043534	blood vessel endothelial cell migration	2.512377e-5
GO:0048705	skeletal system morphogenesis	2.520898e-5
GO:0035105	sterol regulatory element binding protein import into nucleus	2.589246e-5
GO:0043304	regulation of mast cell degranulation	2.774836e-5
GO:0032863	activation of Rac GTPase activity	2.820118e-5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	2.823477e-5
GO:0060706	cell differentiation involved in embryonic placenta development	2.845809e-5
GO:0045794	negative regulation of cell volume	2.891639e-5
GO:0019388	galactose catabolic process	2.933844e-5
GO:0009070	serine family amino acid biosynthetic process	2.952824e-5
GO:0002071	glandular epithelial cell maturation	3.066535e-5
GO:0033235	positive regulation of protein sumoylation	3.093410e-5
GO:0060124	positive regulation of growth hormone secretion	3.137851e-5
GO:0070256	negative regulation of mucus secretion	3.174028e-5
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	3.174028e-5
GO:0010718	positive regulation of epithelial to mesenchymal transition	3.212570e-5
GO:0043300	regulation of leukocyte degranulation	3.303833e-5
GO:0043088	regulation of Cdc42 GTPase activity	3.379826e-5
GO:0060073	micturition	3.412679e-5
GO:0048627	myoblast development	3.445961e-5
GO:0001909	leukocyte mediated cytotoxicity	3.499256e-5
GO:0060346	bone trabecula formation	3.899215e-5
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.905833e-5
GO:0060020	Bergmann glial cell differentiation	3.907661e-5
GO:0071732	cellular response to nitric oxide	3.965025e-5
GO:0006475	internal protein amino acid acetylation	4.042202e-5
GO:0055009	atrial cardiac muscle tissue morphogenesis	4.136803e-5
GO:0060670	branching involved in embryonic placenta morphogenesis	4.148651e-5
GO:0006012	galactose metabolic process	4.239362e-5
GO:0071071	regulation of phospholipid biosynthetic process	4.351959e-5
GO:0044259	multicellular organismal macromolecule metabolic process	4.423528e-5
GO:0010511	regulation of phosphatidylinositol biosynthetic process	4.445383e-5
GO:0070875	positive regulation of glycogen metabolic process	4.523309e-5
GO:0010717	regulation of epithelial to mesenchymal transition	4.618331e-5
GO:0044243	multicellular organismal catabolic process	4.748613e-5
GO:0002017	regulation of blood volume by renal aldosterone	4.971523e-5
GO:0051013	microtubule severing	4.998929e-5
GO:0019064	viral envelope fusion with host membrane	4.998929e-5
GO:0031017	exocrine pancreas development	5.045493e-5
GO:0018277	protein deamination	5.420844e-5
GO:0006353	transcription termination, DNA-dependent	5.426616e-5
GO:0034969	histone arginine methylation	5.695428e-5
GO:0000389	nuclear mRNA 3'-splice site recognition	5.886003e-5
GO:0014848	urinary tract smooth muscle contraction	5.894625e-5
GO:0071072	negative regulation of phospholipid biosynthetic process	6.265631e-5
GO:0070327	thyroid hormone transport	6.316286e-5
GO:0005979	regulation of glycogen biosynthetic process	6.401879e-5
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	6.481718e-5
GO:0015695	organic cation transport	6.755928e-5
GO:0002432	granuloma formation	6.863369e-5
GO:0032012	regulation of ARF protein signal transduction	7.164261e-5
GO:0032963	collagen metabolic process	7.172445e-5
GO:0043487	regulation of RNA stability	7.276667e-5
GO:0018393	internal peptidyl-lysine acetylation	7.781185e-5
GO:0006545	glycine biosynthetic process	7.873351e-5
GO:0032526	response to retinoic acid	7.876315e-5
GO:0071316	cellular response to nicotine	7.987597e-5
GO:0071514	genetic imprinting	8.179285e-5
GO:0090200	positive regulation of release of cytochrome c from mitochondria	8.266279e-5
GO:0010900	negative regulation of phosphatidylcholine catabolic process	8.303033e-5
GO:0006083	acetate metabolic process	8.303033e-5
GO:0090102	cochlea development	8.410720e-5
GO:0050746	regulation of lipoprotein metabolic process	8.442162e-5
GO:0033233	regulation of protein sumoylation	8.503181e-5
GO:0072337	modified amino acid transport	9.038259e-5
GO:0051956	negative regulation of amino acid transport	9.189024e-5
GO:0046814	virion attachment, binding of host cell surface coreceptor	9.230340e-5
GO:0043543	protein acylation	9.379014e-5
GO:0051438	regulation of ubiquitin-protein ligase activity	9.439542e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	9.804416e-5
GO:0006473	protein acetylation	1.000298e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	1.036241e-4
GO:0061144	alveolar secondary septum development	1.041502e-4
GO:0018394	peptidyl-lysine acetylation	1.062318e-4
GO:0035313	wound healing, spreading of epidermal cells	1.071553e-4
GO:0000022	mitotic spindle elongation	1.113703e-4
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	1.113703e-4
GO:0002636	positive regulation of germinal center formation	1.123739e-4
GO:0000302	response to reactive oxygen species	1.152972e-4
GO:0007020	microtubule nucleation	1.168899e-4
GO:0045932	negative regulation of muscle contraction	1.216087e-4
GO:0048703	embryonic viscerocranium morphogenesis	1.226757e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	1.243825e-4
GO:0043303	mast cell degranulation	1.246192e-4
GO:0001957	intramembranous ossification	1.256428e-4
GO:0060872	semicircular canal development	1.262878e-4
GO:0010822	positive regulation of mitochondrion organization	1.276908e-4
GO:0015696	ammonium transport	1.289013e-4
GO:0055093	response to hyperoxia	1.409607e-4
GO:0006360	transcription from RNA polymerase I promoter	1.469874e-4
GO:0010896	regulation of triglyceride catabolic process	1.486425e-4
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.490739e-4
GO:0015879	carnitine transport	1.532897e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.566594e-4
GO:0010897	negative regulation of triglyceride catabolic process	1.566594e-4
GO:0009264	deoxyribonucleotide catabolic process	1.567066e-4
GO:0046730	induction of host immune response by virus	1.643184e-4
GO:0032006	regulation of TOR signaling cascade	1.692584e-4
GO:0051546	keratinocyte migration	1.746911e-4
GO:0022617	extracellular matrix disassembly	1.764259e-4
GO:0060711	labyrinthine layer development	1.782011e-4
GO:0035470	positive regulation of vascular wound healing	1.799692e-4
GO:0015747	urate transport	1.799692e-4
GO:0042396	phosphagen biosynthetic process	1.826708e-4
GO:0045799	positive regulation of chromatin assembly or disassembly	1.919391e-4
GO:0035499	carnosine biosynthetic process	1.919391e-4
GO:0002385	mucosal immune response	1.922945e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	2.049130e-4
GO:0006289	nucleotide-excision repair	2.163281e-4
GO:0021508	floor plate formation	2.170435e-4
GO:0048549	positive regulation of pinocytosis	2.170435e-4
GO:0070873	regulation of glycogen metabolic process	2.172931e-4
GO:0051591	response to cAMP	2.188269e-4
GO:0006283	transcription-coupled nucleotide-excision repair	2.197163e-4
GO:0043314	negative regulation of neutrophil degranulation	2.198545e-4
GO:0090086	negative regulation of protein deubiquitination	2.264644e-4
GO:0071242	cellular response to ammonium ion	2.264644e-4
GO:0001977	renal system process involved in regulation of blood volume	2.277851e-4
GO:0035813	regulation of renal sodium excretion	2.298726e-4
GO:0044319	wound healing, spreading of cells	2.394166e-4
GO:0060343	trabecula formation	2.417252e-4
GO:0090103	cochlea morphogenesis	2.430441e-4
GO:0031330	negative regulation of cellular catabolic process	2.449316e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	2.462045e-4
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2.472364e-4
GO:0006268	DNA unwinding involved in replication	2.485411e-4
GO:0003084	positive regulation of systemic arterial blood pressure	2.507807e-4
GO:0071394	cellular response to testosterone stimulus	2.649494e-4
GO:0070345	negative regulation of fat cell proliferation	2.702236e-4
GO:0071300	cellular response to retinoic acid	2.704430e-4
GO:0061038	uterus morphogenesis	2.859857e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	2.863244e-4
GO:0048242	epinephrine secretion	2.895368e-4
GO:0045575	basophil activation	2.962080e-4
GO:0001694	histamine biosynthetic process	2.962080e-4
GO:0035854	eosinophil fate commitment	3.007002e-4
GO:0030222	eosinophil differentiation	3.007002e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	3.026613e-4
GO:0045217	cell-cell junction maintenance	3.040498e-4
GO:0055010	ventricular cardiac muscle tissue morphogenesis	3.040734e-4
GO:0014832	urinary bladder smooth muscle contraction	3.090949e-4
GO:0090312	positive regulation of protein deacetylation	3.239871e-4
GO:0015939	pantothenate metabolic process	3.260484e-4
GO:0045940	positive regulation of steroid metabolic process	3.279247e-4
GO:0045655	regulation of monocyte differentiation	3.313552e-4
GO:0001300	chronological cell aging	3.334652e-4
GO:0045657	positive regulation of monocyte differentiation	3.428489e-4
GO:0043985	histone H4-R3 methylation	3.455334e-4
GO:0001546	preantral ovarian follicle growth	3.537241e-4
GO:0035732	nitric oxide storage	3.537241e-4
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	3.537241e-4
GO:0035726	common myeloid progenitor cell proliferation	3.537241e-4
GO:0031065	positive regulation of histone deacetylation	3.612537e-4
GO:0060014	granulosa cell differentiation	3.651695e-4
GO:0051005	negative regulation of lipoprotein lipase activity	3.667405e-4
GO:0006458	'de novo' protein folding	3.676541e-4
GO:0002678	positive regulation of chronic inflammatory response	3.716364e-4
GO:0003229	ventricular cardiac muscle tissue development	3.726389e-4
GO:0046732	active induction of host immune response by virus	3.750114e-4
GO:0048708	astrocyte differentiation	3.781844e-4
GO:2000273	positive regulation of receptor activity	4.070064e-4
GO:0002448	mast cell mediated immunity	4.108603e-4
GO:0032425	positive regulation of mismatch repair	4.312923e-4
GO:0021562	vestibulocochlear nerve development	4.312923e-4
GO:0002443	leukocyte mediated immunity	4.359967e-4
GO:0000422	mitochondrion degradation	4.390698e-4
GO:0061304	retinal blood vessel morphogenesis	4.431734e-4
GO:0050861	positive regulation of B cell receptor signaling pathway	4.463763e-4
GO:0002426	immunoglobulin production in mucosal tissue	4.527987e-4
GO:0032793	positive regulation of CREB transcription factor activity	4.542474e-4
GO:0061370	testosterone biosynthetic process	4.636116e-4
GO:0060160	negative regulation of dopamine receptor signaling pathway	4.636116e-4
GO:0050756	fractalkine metabolic process	4.636116e-4
GO:0033595	response to genistein	4.636116e-4
GO:0033006	regulation of mast cell activation involved in immune response	4.677240e-4
GO:0019883	antigen processing and presentation of endogenous antigen	4.720232e-4
GO:0007028	cytoplasm organization	4.857908e-4
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	4.883283e-4
GO:0032796	uropod organization	4.991365e-4
GO:0040015	negative regulation of multicellular organism growth	5.233141e-4
GO:0000084	S phase of mitotic cell cycle	5.294156e-4
GO:0046110	xanthine metabolic process	5.366834e-4
GO:0015858	nucleoside transport	5.398522e-4
GO:0002921	negative regulation of humoral immune response	5.440429e-4
GO:0043585	nose morphogenesis	5.467648e-4
GO:0043353	enucleate erythrocyte differentiation	5.483715e-4
GO:0006354	transcription elongation, DNA-dependent	5.534592e-4
GO:0090205	positive regulation of cholesterol metabolic process	5.551333e-4
GO:0002026	regulation of the force of heart contraction	5.756715e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	5.839312e-4
GO:0031365	N-terminal protein amino acid modification	5.950815e-4
GO:0046718	entry of virus into host cell	6.027952e-4
GO:0017187	peptidyl-glutamic acid carboxylation	6.028748e-4
GO:0061383	trabecula morphogenesis	6.057120e-4
GO:0006423	cysteinyl-tRNA aminoacylation	6.071512e-4
GO:0070943	neutrophil mediated killing of symbiont cell	6.261819e-4
GO:0044258	intestinal lipid catabolic process	6.380331e-4
GO:0018350	protein esterification	6.380331e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	6.380331e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	6.416023e-4
GO:0001560	regulation of cell growth by extracellular stimulus	6.463325e-4
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	6.498817e-4
GO:0048382	mesendoderm development	6.498817e-4
GO:0097045	phosphatidylserine exposure on blood platelet	6.518744e-4
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	6.518744e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	6.518744e-4
GO:0055026	negative regulation of cardiac muscle tissue development	6.534028e-4
GO:0045948	positive regulation of translational initiation	6.545106e-4
GO:0043313	regulation of neutrophil degranulation	6.546162e-4
GO:0051444	negative regulation of ubiquitin-protein ligase activity	6.594737e-4
GO:0007288	sperm axoneme assembly	6.835464e-4
GO:0014002	astrocyte development	6.939723e-4
GO:0060828	regulation of canonical Wnt receptor signaling pathway	6.949872e-4
GO:0016573	histone acetylation	6.961387e-4
GO:0051298	centrosome duplication	7.060467e-4
GO:0031668	cellular response to extracellular stimulus	7.113327e-4
GO:0060707	trophoblast giant cell differentiation	7.227945e-4
GO:0060215	primitive hemopoiesis	7.265923e-4
GO:0050434	positive regulation of viral transcription	7.323097e-4
GO:2000249	regulation of actin cytoskeleton reorganization	7.405408e-4
GO:0023019	signal transduction involved in regulation of gene expression	7.442250e-4
GO:0061143	alveolar primary septum development	7.488866e-4
GO:0044342	type B pancreatic cell proliferation	7.488866e-4
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	7.488866e-4
GO:0010918	positive regulation of mitochondrial membrane potential	7.488866e-4
GO:0006449	regulation of translational termination	7.498258e-4
GO:0002679	respiratory burst involved in defense response	7.808986e-4
GO:0032008	positive regulation of TOR signaling cascade	7.862009e-4
GO:0035247	peptidyl-arginine omega-N-methylation	7.971714e-4
GO:0035573	N-terminal peptidyl-serine trimethylation	8.009578e-4
GO:0035572	N-terminal peptidyl-serine dimethylation	8.009578e-4
GO:0018012	N-terminal peptidyl-alanine trimethylation	8.009578e-4
GO:0018016	N-terminal peptidyl-proline dimethylation	8.009578e-4
GO:0061157	mRNA destabilization	8.186957e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	8.186957e-4
GO:0051693	actin filament capping	8.338417e-4
GO:0033590	response to cobalamin	8.373752e-4
GO:0006117	acetaldehyde metabolic process	8.373752e-4
GO:0006342	chromatin silencing	8.471376e-4
GO:0048320	axial mesoderm formation	8.498768e-4
GO:0060620	regulation of cholesterol import	8.498768e-4
GO:0002513	tolerance induction to self antigen	8.514871e-4
GO:0043299	leukocyte degranulation	8.596481e-4
GO:0090207	regulation of triglyceride metabolic process	8.747442e-4
GO:0051017	actin filament bundle assembly	8.757860e-4
GO:0051788	response to misfolded protein	8.781383e-4
GO:0060621	negative regulation of cholesterol import	8.888903e-4
GO:0032321	positive regulation of Rho GTPase activity	8.891255e-4
GO:0033146	regulation of estrogen receptor signaling pathway	8.936637e-4
GO:0051340	regulation of ligase activity	8.943122e-4
GO:0050747	positive regulation of lipoprotein metabolic process	9.051173e-4
GO:0060696	regulation of phospholipid catabolic process	9.224014e-4
GO:0006285	base-excision repair, AP site formation	9.272464e-4
GO:0032383	regulation of intracellular cholesterol transport	9.456187e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	9.456187e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	9.603548e-4
GO:0090085	regulation of protein deubiquitination	9.633807e-4
GO:0018208	peptidyl-proline modification	9.751159e-4
GO:0030221	basophil differentiation	9.868828e-4
GO:0046655	folic acid metabolic process	1.008992e-3
GO:0001941	postsynaptic membrane organization	1.008992e-3
GO:0032862	activation of Rho GTPase activity	1.055001e-3
GO:0035089	establishment of apical/basal cell polarity	1.057544e-3
GO:0046006	regulation of activated T cell proliferation	1.064674e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.100480e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.112536e-3
GO:0002579	positive regulation of antigen processing and presentation	1.118841e-3
GO:0060083	smooth muscle contraction involved in micturition	1.126450e-3
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1.126450e-3
GO:0000093	mitotic telophase	1.136091e-3
GO:0035095	behavioral response to nicotine	1.146344e-3
GO:0048255	mRNA stabilization	1.163808e-3
GO:0035364	thymine transport	1.201327e-3
GO:0035344	hypoxanthine transport	1.201327e-3
GO:0021528	commissural neuron differentiation in spinal cord	1.201327e-3
GO:0015854	guanine transport	1.201327e-3
GO:0007271	synaptic transmission, cholinergic	1.203884e-3
GO:0007172	signal complex assembly	1.213369e-3
GO:0032312	regulation of ARF GTPase activity	1.216394e-3
GO:0071549	cellular response to dexamethasone stimulus	1.230706e-3
GO:0010742	macrophage derived foam cell differentiation	1.235774e-3
GO:0030574	collagen catabolic process	1.240036e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	1.240802e-3
GO:0042335	cuticle development	1.250634e-3
GO:0010986	positive regulation of lipoprotein particle clearance	1.250634e-3
GO:0032417	positive regulation of sodium:hydrogen antiporter activity	1.299170e-3
GO:0031536	positive regulation of exit from mitosis	1.302259e-3
GO:0043488	regulation of mRNA stability	1.335300e-3
GO:0032423	regulation of mismatch repair	1.366309e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.366309e-3
GO:0007296	vitellogenesis	1.369680e-3
GO:0060713	labyrinthine layer morphogenesis	1.374854e-3
GO:0031284	positive regulation of guanylate cyclase activity	1.379671e-3
GO:0015742	alpha-ketoglutarate transport	1.379671e-3
GO:0031670	cellular response to nutrient	1.385572e-3
GO:0090150	establishment of protein localization in membrane	1.391050e-3
GO:0048733	sebaceous gland development	1.419853e-3
GO:0097107	postsynaptic density assembly	1.420983e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.420983e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	1.455132e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.488578e-3
GO:0009817	defense response to fungus, incompatible interaction	1.488578e-3
GO:0010288	response to lead ion	1.497498e-3
GO:0051084	'de novo' posttranslational protein folding	1.529664e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.538934e-3
GO:0000216	M/G1 transition of mitotic cell cycle	1.566524e-3
GO:0050881	musculoskeletal movement	1.579101e-3
GO:0033037	polysaccharide localization	1.607822e-3
GO:0032462	regulation of protein homooligomerization	1.668611e-3
GO:0071956	cellular component maintenance at cellular level	1.677313e-3
GO:0003416	endochondral bone growth	1.677313e-3
GO:0030206	chondroitin sulfate biosynthetic process	1.685944e-3
GO:0000413	protein peptidyl-prolyl isomerization	1.687633e-3
GO:0000132	establishment of mitotic spindle orientation	1.733125e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	1.741402e-3
GO:0022616	DNA strand elongation	1.741402e-3
GO:0030007	cellular potassium ion homeostasis	1.757690e-3
GO:0045112	integrin biosynthetic process	1.778952e-3
GO:0006560	proline metabolic process	1.778952e-3
GO:0090130	tissue migration	1.779616e-3
GO:0060253	negative regulation of glial cell proliferation	1.791609e-3
GO:0071731	response to nitric oxide	1.806787e-3
GO:0007184	SMAD protein import into nucleus	1.806787e-3
GO:0070489	T cell aggregation	1.843447e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.880441e-3
GO:0021526	medial motor column neuron differentiation	1.896653e-3
GO:0043306	positive regulation of mast cell degranulation	1.915651e-3
GO:0007044	cell-substrate junction assembly	1.926611e-3
GO:0009253	peptidoglycan catabolic process	1.983988e-3
GO:0061205	paramesonephric duct development	1.983988e-3
GO:0009651	response to salt stress	1.991658e-3
GO:0051580	regulation of neurotransmitter uptake	2.017070e-3
GO:0048752	semicircular canal morphogenesis	2.025566e-3
GO:0010225	response to UV-C	2.050447e-3
GO:0007506	gonadal mesoderm development	2.055436e-3
GO:0016048	detection of temperature stimulus	2.056751e-3
GO:0060169	negative regulation of adenosine receptor signaling pathway	2.077966e-3
GO:0060407	negative regulation of penile erection	2.077966e-3
GO:0002314	germinal center B cell differentiation	2.077966e-3
GO:0046111	xanthine biosynthetic process	2.077966e-3
GO:0046061	dATP catabolic process	2.077966e-3
GO:0006157	deoxyadenosine catabolic process	2.077966e-3
GO:0001829	trophectodermal cell differentiation	2.079424e-3
GO:0060179	male mating behavior	2.090258e-3
GO:2000188	regulation of cholesterol homeostasis	2.090258e-3
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	2.090258e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	2.168831e-3
GO:0050872	white fat cell differentiation	2.213279e-3
GO:0071299	cellular response to vitamin A	2.246670e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	2.272622e-3
GO:0042267	natural killer cell mediated cytotoxicity	2.276620e-3
GO:0002676	regulation of chronic inflammatory response	2.298351e-3
GO:0016032	viral reproduction	2.366827e-3
GO:0045806	negative regulation of endocytosis	2.369319e-3
GO:0060956	endocardial cell differentiation	2.376495e-3
GO:0061302	smooth muscle cell-matrix adhesion	2.456929e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.456929e-3
GO:0046607	positive regulation of centrosome cycle	2.456929e-3
GO:0035845	photoreceptor cell outer segment organization	2.456929e-3
GO:0042994	cytoplasmic sequestering of transcription factor	2.475662e-3
GO:0032464	positive regulation of protein homooligomerization	2.483968e-3
GO:0070309	lens fiber cell morphogenesis	2.523255e-3
GO:0071874	cellular response to norepinephrine stimulus	2.563948e-3
GO:0060084	synaptic transmission involved in micturition	2.563948e-3
GO:0003105	negative regulation of glomerular filtration	2.563948e-3
GO:0070483	detection of hypoxia	2.609357e-3
GO:0019318	hexose metabolic process	2.637861e-3
GO:0009069	serine family amino acid metabolic process	2.638156e-3
GO:0051645	Golgi localization	2.696315e-3
GO:0051365	cellular response to potassium ion starvation	2.696315e-3
GO:0021570	rhombomere 4 development	2.696315e-3
GO:0006097	glyoxylate cycle	2.696315e-3
GO:0030157	pancreatic juice secretion	2.779386e-3
GO:0032319	regulation of Rho GTPase activity	2.792772e-3
GO:0033504	floor plate development	2.801959e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	2.826997e-3
GO:0043467	regulation of generation of precursor metabolites and energy	2.832342e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	2.885541e-3
GO:0042104	positive regulation of activated T cell proliferation	2.917188e-3
GO:0009304	tRNA transcription	2.945185e-3
GO:0071496	cellular response to external stimulus	2.952094e-3
GO:0072011	glomerular endothelium development	3.069703e-3
GO:0072144	glomerular mesangial cell development	3.069703e-3
GO:0060035	notochord cell development	3.069703e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	3.079672e-3
GO:0015809	arginine transport	3.111939e-3
GO:0032926	negative regulation of activin receptor signaling pathway	3.126813e-3
GO:0060123	regulation of growth hormone secretion	3.139038e-3
GO:0015862	uridine transport	3.142298e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	3.146351e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	3.152115e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	3.219719e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	3.304449e-3
GO:0016056	rhodopsin mediated signaling pathway	3.310853e-3
GO:0006013	mannose metabolic process	3.391722e-3
GO:0060998	regulation of dendritic spine development	3.410019e-3
GO:0071392	cellular response to estradiol stimulus	3.455444e-3
GO:0042093	T-helper cell differentiation	3.455444e-3
GO:0031297	replication fork processing	3.519029e-3
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	3.519029e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	3.559944e-3
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	3.598637e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0060192	negative regulation of lipase activity	7.771046e-10
GO:0050995	negative regulation of lipid catabolic process	4.802686e-9
GO:0072109	glomerular mesangium development	7.903130e-9
GO:0033700	phospholipid efflux	1.924874e-8
GO:0072124	regulation of glomerular mesangial cell proliferation	3.350188e-8
GO:0007522	visceral muscle development	4.201374e-8
GO:0051005	negative regulation of lipoprotein lipase activity	5.166701e-8
GO:0034382	chylomicron remnant clearance	5.166701e-8
GO:0031331	positive regulation of cellular catabolic process	5.436244e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.495782e-8
GO:0042304	regulation of fatty acid biosynthetic process	7.902019e-8
GO:0071072	negative regulation of phospholipid biosynthetic process	1.070520e-7
GO:0071071	regulation of phospholipid biosynthetic process	1.092978e-7
GO:0009082	branched chain family amino acid biosynthetic process	1.447139e-7
GO:0033344	cholesterol efflux	1.451982e-7
GO:0032365	intracellular lipid transport	1.459824e-7
GO:0043462	regulation of ATPase activity	1.577567e-7
GO:0050994	regulation of lipid catabolic process	1.624089e-7
GO:0046890	regulation of lipid biosynthetic process	1.673787e-7
GO:0045833	negative regulation of lipid metabolic process	2.023181e-7
GO:0090192	regulation of glomerulus development	2.890749e-7
GO:0050779	RNA destabilization	3.130622e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	7.817280e-7
GO:0010897	negative regulation of triglyceride catabolic process	7.817280e-7
GO:0048246	macrophage chemotaxis	1.205814e-6
GO:0045862	positive regulation of proteolysis	1.272901e-6
GO:0071316	cellular response to nicotine	1.495216e-6
GO:0002439	chronic inflammatory response to antigenic stimulus	1.495216e-6
GO:0002036	regulation of L-glutamate transport	1.829964e-6
GO:0072044	collecting duct development	1.848326e-6
GO:0032367	intracellular cholesterol transport	1.954666e-6
GO:0051956	negative regulation of amino acid transport	2.453188e-6
GO:0072144	glomerular mesangial cell development	2.576414e-6
GO:0009948	anterior/posterior axis specification	2.622105e-6
GO:0045749	negative regulation of S phase of mitotic cell cycle	2.757814e-6
GO:0030049	muscle filament sliding	3.646989e-6
GO:0048484	enteric nervous system development	3.789361e-6
GO:0060621	negative regulation of cholesterol import	4.282685e-6
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	4.308562e-6
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	4.342638e-6
GO:0003219	cardiac right ventricle formation	4.732655e-6
GO:0032049	cardiolipin biosynthetic process	4.928574e-6
GO:0008595	anterior/posterior axis specification, embryo	5.959820e-6
GO:0031442	positive regulation of mRNA 3'-end processing	7.129187e-6
GO:0072125	negative regulation of glomerular mesangial cell proliferation	7.138254e-6
GO:0003229	ventricular cardiac muscle tissue development	7.322252e-6
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	7.441806e-6
GO:0002268	follicular dendritic cell differentiation	7.554470e-6
GO:0072215	regulation of metanephros development	8.127862e-6
GO:0010985	negative regulation of lipoprotein particle clearance	8.526748e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	8.614014e-6
GO:0031329	regulation of cellular catabolic process	1.017985e-5
GO:0070328	triglyceride homeostasis	1.033972e-5
GO:0090183	regulation of kidney development	1.041919e-5
GO:0007422	peripheral nervous system development	1.050699e-5
GO:0048739	cardiac muscle fiber development	1.109639e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1.249241e-5
GO:0072110	glomerular mesangial cell proliferation	1.284984e-5
GO:0061046	regulation of branching involved in lung morphogenesis	1.293847e-5
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.299404e-5
GO:0051055	negative regulation of lipid biosynthetic process	1.339906e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.427714e-5
GO:0045994	positive regulation of translational initiation by iron	1.427714e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.427714e-5
GO:0002037	negative regulation of L-glutamate transport	1.427714e-5
GO:0035441	cell migration involved in vasculogenesis	1.653044e-5
GO:0007386	compartment pattern specification	1.798941e-5
GO:0045930	negative regulation of mitotic cell cycle	1.828339e-5
GO:0043691	reverse cholesterol transport	1.868286e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	2.062169e-5
GO:0044240	multicellular organismal lipid catabolic process	2.118406e-5
GO:0061014	positive regulation of mRNA catabolic process	2.194521e-5
GO:0060444	branching involved in mammary gland duct morphogenesis	2.251049e-5
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	2.305876e-5
GO:0072143	mesangial cell development	2.332292e-5
GO:0060033	anatomical structure regression	2.362322e-5
GO:0033085	negative regulation of T cell differentiation in thymus	2.389644e-5
GO:0003002	regionalization	2.414955e-5
GO:0010718	positive regulation of epithelial to mesenchymal transition	2.729086e-5
GO:0048261	negative regulation of receptor-mediated endocytosis	2.817474e-5
GO:0032571	response to vitamin K	3.009323e-5
GO:0090102	cochlea development	3.387804e-5
GO:0060693	regulation of branching involved in salivary gland morphogenesis	3.400589e-5
GO:0071333	cellular response to glucose stimulus	3.421667e-5
GO:0046580	negative regulation of Ras protein signal transduction	3.447172e-5
GO:0001678	cellular glucose homeostasis	3.455592e-5
GO:0003156	regulation of organ formation	3.465490e-5
GO:0033088	negative regulation of immature T cell proliferation in thymus	3.476044e-5
GO:0034447	very-low-density lipoprotein particle clearance	3.504981e-5
GO:0006863	purine base transport	3.708139e-5
GO:0045792	negative regulation of cell size	4.210709e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	4.308299e-5
GO:0006817	phosphate ion transport	4.324865e-5
GO:0000305	response to oxygen radical	4.457983e-5
GO:0065005	protein-lipid complex assembly	4.488445e-5
GO:0014015	positive regulation of gliogenesis	4.595308e-5
GO:0006474	N-terminal protein amino acid acetylation	5.084515e-5
GO:0031440	regulation of mRNA 3'-end processing	5.614496e-5
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	6.266925e-5
GO:0071300	cellular response to retinoic acid	6.418812e-5
GO:0045080	positive regulation of chemokine biosynthetic process	6.425757e-5
GO:0051058	negative regulation of small GTPase mediated signal transduction	6.545441e-5
GO:0010984	regulation of lipoprotein particle clearance	6.696420e-5
GO:0033083	regulation of immature T cell proliferation	6.844657e-5
GO:0071322	cellular response to carbohydrate stimulus	7.033932e-5
GO:0015802	basic amino acid transport	7.110578e-5
GO:0019048	virus-host interaction	7.839204e-5
GO:0060688	regulation of morphogenesis of a branching structure	8.377078e-5
GO:0045618	positive regulation of keratinocyte differentiation	8.537611e-5
GO:0072074	kidney mesenchyme development	8.595409e-5
GO:0072012	glomerulus vasculature development	8.937870e-5
GO:0003205	cardiac chamber development	9.356281e-5
GO:0010717	regulation of epithelial to mesenchymal transition	9.946720e-5
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	1.022955e-4
GO:0071422	succinate transmembrane transport	1.035364e-4
GO:0046889	positive regulation of lipid biosynthetic process	1.040421e-4
GO:0006558	L-phenylalanine metabolic process	1.049157e-4
GO:0045606	positive regulation of epidermal cell differentiation	1.064722e-4
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.080793e-4
GO:0032048	cardiolipin metabolic process	1.082246e-4
GO:0090103	cochlea morphogenesis	1.155013e-4
GO:0003206	cardiac chamber morphogenesis	1.155149e-4
GO:0042267	natural killer cell mediated cytotoxicity	1.164408e-4
GO:0071299	cellular response to vitamin A	1.216585e-4
GO:0060620	regulation of cholesterol import	1.233597e-4
GO:0010823	negative regulation of mitochondrion organization	1.363631e-4
GO:0060026	convergent extension	1.372722e-4
GO:0003209	cardiac atrium morphogenesis	1.396748e-4
GO:0001710	mesodermal cell fate commitment	1.414126e-4
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.437739e-4
GO:0000271	polysaccharide biosynthetic process	1.451268e-4
GO:0014829	vascular smooth muscle contraction	1.477968e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.485779e-4
GO:0045055	regulated secretory pathway	1.551705e-4
GO:0061013	regulation of mRNA catabolic process	1.557000e-4
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.678667e-4
GO:0048332	mesoderm morphogenesis	1.700224e-4
GO:0043587	tongue morphogenesis	1.725758e-4
GO:0045940	positive regulation of steroid metabolic process	1.736608e-4
GO:0071529	cementum mineralization	1.895783e-4
GO:0034369	plasma lipoprotein particle remodeling	1.932198e-4
GO:0009103	lipopolysaccharide biosynthetic process	1.937953e-4
GO:0001885	endothelial cell development	1.976251e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.989601e-4
GO:0014037	Schwann cell differentiation	2.038650e-4
GO:0007501	mesodermal cell fate specification	2.176942e-4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	2.239215e-4
GO:0002221	pattern recognition receptor signaling pathway	2.315789e-4
GO:0032375	negative regulation of cholesterol transport	2.319231e-4
GO:0072015	glomerular visceral epithelial cell development	2.457769e-4
GO:0006559	L-phenylalanine catabolic process	2.457769e-4
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.505626e-4
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.505626e-4
GO:0000185	activation of MAPKKK activity	2.630672e-4
GO:0003231	cardiac ventricle development	2.745925e-4
GO:0014044	Schwann cell development	2.772705e-4
GO:0071803	positive regulation of podosome assembly	3.041861e-4
GO:0030241	skeletal muscle myosin thick filament assembly	3.041861e-4
GO:0042363	fat-soluble vitamin catabolic process	3.041861e-4
GO:0034375	high-density lipoprotein particle remodeling	3.111791e-4
GO:0006656	phosphatidylcholine biosynthetic process	3.119589e-4
GO:0033084	regulation of immature T cell proliferation in thymus	3.139016e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	3.148204e-4
GO:0045922	negative regulation of fatty acid metabolic process	3.149936e-4
GO:0014040	positive regulation of Schwann cell differentiation	3.151271e-4
GO:0006668	sphinganine-1-phosphate metabolic process	3.151271e-4
GO:0033239	negative regulation of cellular amine metabolic process	3.191560e-4
GO:0060696	regulation of phospholipid catabolic process	3.196310e-4
GO:0021515	cell differentiation in spinal cord	3.234564e-4
GO:0003230	cardiac atrium development	3.234564e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.358494e-4
GO:0002739	regulation of cytokine secretion involved in immune response	3.380410e-4
GO:0045687	positive regulation of glial cell differentiation	3.525504e-4
GO:0014824	artery smooth muscle contraction	3.538269e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	3.538269e-4
GO:0048012	hepatocyte growth factor receptor signaling pathway	3.547358e-4
GO:0042149	cellular response to glucose starvation	3.560979e-4
GO:0046470	phosphatidylcholine metabolic process	3.570336e-4
GO:0003215	cardiac right ventricle morphogenesis	3.713993e-4
GO:0072017	distal tubule development	3.777078e-4
GO:0030421	defecation	3.820859e-4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	3.857914e-4
GO:0001886	endothelial cell morphogenesis	3.857914e-4
GO:0032148	activation of protein kinase B activity	3.857914e-4
GO:0002227	innate immune response in mucosa	3.884424e-4
GO:0018230	peptidyl-L-cysteine S-palmitoylation	3.976959e-4
GO:0043299	leukocyte degranulation	4.044635e-4
GO:0060744	mammary gland branching involved in thelarche	4.075129e-4
GO:0060070	canonical Wnt receptor signaling pathway	4.115246e-4
GO:0045073	regulation of chemokine biosynthetic process	4.214104e-4
GO:0021904	dorsal/ventral neural tube patterning	4.244712e-4
GO:0060923	cardiac muscle cell fate commitment	4.341732e-4
GO:0043491	protein kinase B signaling cascade	4.468114e-4
GO:0010896	regulation of triglyceride catabolic process	4.485759e-4
GO:0072111	cell proliferation involved in kidney development	4.728143e-4
GO:0003208	cardiac ventricle morphogenesis	4.771270e-4
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	4.810692e-4
GO:0032321	positive regulation of Rho GTPase activity	4.911806e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	4.997527e-4
GO:0042373	vitamin K metabolic process	5.027465e-4
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	5.049752e-4
GO:0014807	regulation of somitogenesis	5.049752e-4
GO:0072298	regulation of metanephric glomerulus development	5.158208e-4
GO:0032495	response to muramyl dipeptide	5.162486e-4
GO:0060638	mesenchymal-epithelial cell signaling	5.164347e-4
GO:0006546	glycine catabolic process	5.328019e-4
GO:0009894	regulation of catabolic process	5.428051e-4
GO:0002758	innate immune response-activating signal transduction	5.435241e-4
GO:0006982	response to lipid hydroperoxide	5.620935e-4
GO:0051323	metaphase	5.620935e-4
GO:0006171	cAMP biosynthetic process	5.693588e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	5.756904e-4
GO:0010511	regulation of phosphatidylinositol biosynthetic process	6.483792e-4
GO:0015760	glucose-6-phosphate transport	6.483792e-4
GO:0071827	plasma lipoprotein particle organization	6.600891e-4
GO:0001658	branching involved in ureteric bud morphogenesis	6.749905e-4
GO:0072205	metanephric collecting duct development	7.117528e-4
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	7.298368e-4
GO:0043031	negative regulation of macrophage activation	7.298368e-4
GO:0072278	metanephric comma-shaped body morphogenesis	7.405257e-4
GO:0050935	iridophore differentiation	7.405257e-4
GO:0072284	metanephric S-shaped body morphogenesis	7.405257e-4
GO:0048937	lateral line nerve glial cell development	7.405257e-4
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	7.405257e-4
GO:0009098	leucine biosynthetic process	8.104052e-4
GO:0035674	tricarboxylic acid transmembrane transport	8.104052e-4
GO:0006550	isoleucine catabolic process	8.104052e-4
GO:0032319	regulation of Rho GTPase activity	8.116091e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	8.127756e-4
GO:0060675	ureteric bud morphogenesis	8.241127e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	8.323203e-4
GO:0051156	glucose 6-phosphate metabolic process	8.323203e-4
GO:0006867	asparagine transport	8.323203e-4
GO:0001823	mesonephros development	8.415224e-4
GO:0021681	cerebellar granular layer development	8.491736e-4
GO:2000826	regulation of heart morphogenesis	8.647140e-4
GO:2001037	positive regulation of tongue muscle cell differentiation	9.147928e-4
GO:0051639	actin filament network formation	9.147928e-4
GO:0034653	retinoic acid catabolic process	9.147928e-4
GO:0033590	response to cobalamin	9.170496e-4
GO:0045581	negative regulation of T cell differentiation	9.442611e-4
GO:0061136	regulation of proteasomal protein catabolic process	9.503829e-4
GO:0009584	detection of visible light	9.565297e-4
GO:0000089	mitotic metaphase	9.732362e-4
GO:2000194	regulation of female gonad development	9.735108e-4
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	9.808270e-4
GO:2001076	positive regulation of metanephric ureteric bud development	9.848768e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	9.848768e-4
GO:0007356	thorax and anterior abdomen determination	9.848768e-4
GO:0006189	'de novo' IMP biosynthetic process	9.848768e-4
GO:2000027	regulation of organ morphogenesis	9.897511e-4
GO:0015747	urate transport	1.031849e-3
GO:0030300	regulation of intestinal cholesterol absorption	1.040983e-3
GO:0030818	negative regulation of cAMP biosynthetic process	1.045461e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	1.052309e-3
GO:0072179	nephric duct formation	1.062898e-3
GO:0043154	negative regulation of caspase activity	1.131938e-3
GO:0030513	positive regulation of BMP signaling pathway	1.142607e-3
GO:0045103	intermediate filament-based process	1.142607e-3
GO:2000195	negative regulation of female gonad development	1.161841e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	1.161841e-3
GO:0050685	positive regulation of mRNA processing	1.179512e-3
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1.197871e-3
GO:0055090	acylglycerol homeostasis	1.197871e-3
GO:0001667	ameboidal cell migration	1.199600e-3
GO:0044341	sodium-dependent phosphate transport	1.237870e-3
GO:0048706	embryonic skeletal system development	1.238503e-3
GO:0030301	cholesterol transport	1.249639e-3
GO:0034505	tooth mineralization	1.264263e-3
GO:0042593	glucose homeostasis	1.328469e-3
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.361383e-3
GO:0071506	cellular response to mycophenolic acid	1.361383e-3
GO:0045218	zonula adherens maintenance	1.361383e-3
GO:0050917	sensory perception of umami taste	1.361383e-3
GO:0072011	glomerular endothelium development	1.387850e-3
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.387850e-3
GO:0050823	peptide antigen stabilization	1.387850e-3
GO:0045980	negative regulation of nucleotide metabolic process	1.402796e-3
GO:0030509	BMP signaling pathway	1.423881e-3
GO:0019430	removal of superoxide radicals	1.444535e-3
GO:0034101	erythrocyte homeostasis	1.470330e-3
GO:0030198	extracellular matrix organization	1.477598e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.484627e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.523178e-3
GO:0035645	enteric smooth muscle cell differentiation	1.523178e-3
GO:0007497	posterior midgut development	1.523178e-3
GO:0090184	positive regulation of kidney development	1.532011e-3
GO:0070245	positive regulation of thymocyte apoptosis	1.532011e-3
GO:0010948	negative regulation of cell cycle process	1.571289e-3
GO:0052200	response to host defenses	1.576184e-3
GO:0034372	very-low-density lipoprotein particle remodeling	1.589895e-3
GO:0008203	cholesterol metabolic process	1.623686e-3
GO:0000303	response to superoxide	1.638492e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.651389e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	1.651389e-3
GO:0048295	positive regulation of isotype switching to IgE isotypes	1.661980e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	1.661980e-3
GO:0002275	myeloid cell activation involved in immune response	1.691066e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.718452e-3
GO:0015851	nucleobase transport	1.721568e-3
GO:0090086	negative regulation of protein deubiquitination	1.722607e-3
GO:0050655	dermatan sulfate proteoglycan metabolic process	1.722607e-3
GO:0009642	response to light intensity	1.722607e-3
GO:0097006	regulation of plasma lipoprotein particle levels	1.741667e-3
GO:0032374	regulation of cholesterol transport	1.741837e-3
GO:0070243	regulation of thymocyte apoptosis	1.748341e-3
GO:0070234	positive regulation of T cell apoptosis	1.750080e-3
GO:0001570	vasculogenesis	1.751433e-3
GO:0035372	protein localization to microtubule	1.785446e-3
GO:0007140	male meiosis	1.829635e-3
GO:0048754	branching morphogenesis of a tube	1.842020e-3
GO:0006572	tyrosine catabolic process	1.851328e-3
GO:0090218	positive regulation of lipid kinase activity	1.875351e-3
GO:0001829	trophectodermal cell differentiation	1.926751e-3
GO:0060065	uterus development	1.991700e-3
GO:0016125	sterol metabolic process	2.053412e-3
GO:0046849	bone remodeling	2.074883e-3
GO:2000573	positive regulation of DNA biosynthetic process	2.139649e-3
GO:0045662	negative regulation of myoblast differentiation	2.145039e-3
GO:0033692	cellular polysaccharide biosynthetic process	2.192490e-3
GO:0045921	positive regulation of exocytosis	2.194994e-3
GO:0003222	ventricular trabecular myocardium morphogenesis	2.210436e-3
GO:0031536	positive regulation of exit from mitosis	2.246771e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	2.261133e-3
GO:0007440	foregut morphogenesis	2.263090e-3
GO:0045723	positive regulation of fatty acid biosynthetic process	2.278726e-3
GO:0001755	neural crest cell migration	2.328639e-3
GO:0044058	regulation of digestive system process	2.339373e-3
GO:0072203	cell proliferation involved in metanephros development	2.359799e-3
GO:0010656	negative regulation of muscle cell apoptosis	2.365962e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	2.366046e-3
GO:0046039	GTP metabolic process	2.385586e-3
GO:0071257	cellular response to electrical stimulus	2.388190e-3
GO:0045104	intermediate filament cytoskeleton organization	2.395717e-3
GO:0032488	Cdc42 protein signal transduction	2.409389e-3
GO:0032862	activation of Rho GTPase activity	2.481274e-3
GO:0000578	embryonic axis specification	2.494244e-3
GO:0045834	positive regulation of lipid metabolic process	2.531171e-3
GO:0045684	positive regulation of epidermis development	2.543602e-3
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	2.552004e-3
GO:0031581	hemidesmosome assembly	2.557359e-3
GO:0022011	myelination in peripheral nervous system	2.557359e-3
GO:0072498	embryonic skeletal joint development	2.571930e-3
GO:0006405	RNA export from nucleus	2.572152e-3
GO:0000060	protein import into nucleus, translocation	2.572152e-3
GO:0061077	chaperone-mediated protein folding	2.577245e-3
GO:0015809	arginine transport	2.607096e-3
GO:0060981	cell migration involved in coronary angiogenesis	2.625565e-3
GO:0071670	smooth muscle cell chemotaxis	2.625565e-3
GO:0051725	protein de-ADP-ribosylation	2.625565e-3
GO:0002224	toll-like receptor signaling pathway	2.671864e-3
GO:0072112	glomerular visceral epithelial cell differentiation	2.684646e-3
GO:0006927	transformed cell apoptosis	2.712799e-3
GO:0042274	ribosomal small subunit biogenesis	2.719687e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	2.762418e-3
GO:0046487	glyoxylate metabolic process	2.794999e-3
GO:0032682	negative regulation of chemokine production	2.794999e-3
GO:0009896	positive regulation of catabolic process	2.804289e-3
GO:0042415	norepinephrine metabolic process	2.834285e-3
GO:0090209	negative regulation of triglyceride metabolic process	2.892053e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.942967e-3
GO:0010159	specification of organ position	2.942967e-3
GO:0032012	regulation of ARF protein signal transduction	2.957921e-3
GO:0007141	male meiosis I	2.959312e-3
GO:0010288	response to lead ion	2.973776e-3
GO:0035520	monoubiquitinated protein deubiquitination	2.988565e-3
GO:0071460	cellular response to cell-matrix adhesion	2.988565e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	2.988565e-3
GO:0060160	negative regulation of dopamine receptor signaling pathway	2.990217e-3
GO:0070845	polyubiquitinated misfolded protein transport	2.990217e-3
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	2.990217e-3
GO:0015746	citrate transport	2.990217e-3
GO:0009817	defense response to fungus, incompatible interaction	2.990217e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	2.990217e-3
GO:0033591	response to L-ascorbic acid	3.022280e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	3.024151e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	3.028531e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	3.048548e-3
GO:0030218	erythrocyte differentiation	3.095186e-3
GO:0001707	mesoderm formation	3.098984e-3
GO:0035306	positive regulation of dephosphorylation	3.102564e-3
GO:0021871	forebrain regionalization	3.148087e-3
GO:0060272	embryonic skeletal joint morphogenesis	3.148962e-3
GO:0009952	anterior/posterior pattern specification	3.168810e-3
GO:0034442	regulation of lipoprotein oxidation	3.298127e-3
GO:0072006	nephron development	3.354398e-3
GO:0042703	menstruation	3.365060e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.365060e-3
GO:0019101	female somatic sex determination	3.365060e-3
GO:0060299	negative regulation of sarcomere organization	3.365060e-3
GO:0001579	medium-chain fatty acid transport	3.365060e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	3.365060e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	3.365060e-3
GO:0006285	base-excision repair, AP site formation	3.365060e-3
GO:0043586	tongue development	3.397181e-3
GO:0030865	cortical cytoskeleton organization	3.469275e-3
GO:0060037	pharyngeal system development	3.472475e-3
GO:0046855	inositol phosphate dephosphorylation	3.483934e-3
GO:0072178	nephric duct morphogenesis	3.507972e-3
GO:0021520	spinal cord motor neuron cell fate specification	3.507972e-3
GO:0060686	negative regulation of prostatic bud formation	3.629638e-3
GO:0050908	detection of light stimulus involved in visual perception	3.629638e-3
GO:0050748	negative regulation of lipoprotein metabolic process	3.636766e-3
GO:0071044	histone mRNA catabolic process	3.671855e-3
GO:0010893	positive regulation of steroid biosynthetic process	3.699339e-3
GO:0030219	megakaryocyte differentiation	3.763582e-3
GO:0061138	morphogenesis of a branching epithelium	3.812144e-3
GO:0016032	viral reproduction	3.927503e-3
GO:0006415	translational termination	3.947202e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	3.962033e-3
GO:0002115	store-operated calcium entry	3.962033e-3
GO:0035307	positive regulation of protein dephosphorylation	4.001367e-3
GO:0060685	regulation of prostatic bud formation	4.020744e-3
GO:0051450	myoblast proliferation	4.020744e-3
GO:0007498	mesoderm development	4.052281e-3
GO:0009895	negative regulation of catabolic process	4.053470e-3
GO:0001763	morphogenesis of a branching structure	4.063056e-3
GO:0048793	pronephros development	4.063395e-3
GO:0045620	negative regulation of lymphocyte differentiation	4.074561e-3
GO:0031034	myosin filament assembly	4.088620e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	4.114340e-3
GO:0051148	negative regulation of muscle cell differentiation	4.383614e-3
GO:0051588	regulation of neurotransmitter transport	4.435470e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	4.450080e-3
GO:0060485	mesenchyme development	4.470422e-3
GO:0061097	regulation of protein tyrosine kinase activity	4.479915e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	4.480598e-3
GO:0002385	mucosal immune response	4.494794e-3
GO:0060029	convergent extension involved in organogenesis	4.576706e-3
GO:0018106	peptidyl-histidine phosphorylation	4.610742e-3
GO:0003266	regulation of secondary heart field cardioblast proliferation	4.644568e-3
GO:0015914	phospholipid transport	4.660291e-3
GO:0031639	plasminogen activation	4.749820e-3
GO:0006297	nucleotide-excision repair, DNA gap filling	4.749820e-3
GO:0006603	phosphocreatine metabolic process	4.749820e-3
GO:0060710	chorio-allantoic fusion	4.847111e-3
GO:0007044	cell-substrate junction assembly	4.847710e-3
GO:0072050	S-shaped body morphogenesis	4.855479e-3
GO:0060707	trophoblast giant cell differentiation	4.855479e-3
GO:0072049	comma-shaped body morphogenesis	4.855479e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	4.864934e-3
GO:0019853	L-ascorbic acid biosynthetic process	4.896762e-3
GO:0061049	cell growth involved in cardiac muscle cell development	4.937499e-3
GO:0072255	metanephric glomerular mesangial cell development	4.937499e-3
GO:0045064	T-helper 2 cell differentiation	4.937499e-3
GO:0072264	metanephric glomerular endothelium development	4.937499e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	4.937499e-3
GO:0003104	positive regulation of glomerular filtration	4.937499e-3
GO:0038001	paracrine signaling	4.937499e-3
GO:0008065	establishment of blood-nerve barrier	4.937499e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	4.937499e-3
GO:0009190	cyclic nucleotide biosynthetic process	4.997507e-3
GO:0000460	maturation of 5.8S rRNA	5.004257e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	5.012188e-3
GO:0019049	evasion of host defenses by virus	5.012188e-3
GO:0034377	plasma lipoprotein particle assembly	5.042756e-3
GO:0060976	coronary vasculature development	5.065245e-3
GO:0021978	telencephalon regionalization	5.114157e-3
GO:0010872	regulation of cholesterol esterification	5.126734e-3
GO:0072075	metanephric mesenchyme development	5.136115e-3
GO:0072198	mesenchymal cell proliferation involved in ureter development	5.138324e-3
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	5.138324e-3
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	5.138324e-3
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	5.138324e-3
GO:0072192	ureter epithelial cell differentiation	5.138324e-3
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	5.138324e-3
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	5.138324e-3
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	5.138324e-3
GO:0090194	negative regulation of glomerulus development	5.138324e-3
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	5.138324e-3
GO:0061151	BMP signaling pathway involved in renal system segmentation	5.138324e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	5.138324e-3
GO:0048392	intermediate mesodermal cell differentiation	5.138324e-3
GO:0007500	mesodermal cell fate determination	5.138324e-3
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	5.138324e-3
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	5.138324e-3
GO:0055020	positive regulation of cardiac muscle fiber development	5.138324e-3
GO:0071893	BMP signaling pathway involved in nephric duct formation	5.138324e-3
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	5.138324e-3
GO:0061155	pulmonary artery endothelial tube morphogenesis	5.138324e-3
GO:0060503	bud dilation involved in lung branching	5.138324e-3
GO:0090193	positive regulation of glomerulus development	5.317650e-3
GO:0048568	embryonic organ development	5.335610e-3
GO:0032472	Golgi calcium ion transport	5.335933e-3
GO:0032468	Golgi calcium ion homeostasis	5.335933e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.335933e-3
GO:0031296	B cell costimulation	5.335933e-3
GO:0030026	cellular manganese ion homeostasis	5.335933e-3
GO:0034381	plasma lipoprotein particle clearance	5.340879e-3
GO:0033081	regulation of T cell differentiation in thymus	5.376337e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	5.452581e-3
GO:0048340	paraxial mesoderm morphogenesis	5.452581e-3
GO:0006184	GTP catabolic process	5.490093e-3
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	5.502482e-3
GO:0035304	regulation of protein dephosphorylation	5.514710e-3
GO:0007614	short-term memory	5.514886e-3
GO:0006406	mRNA export from nucleus	5.529917e-3
GO:0048251	elastic fiber assembly	5.535906e-3
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	5.536575e-3
GO:0071294	cellular response to zinc ion	5.536575e-3