Novel motif:58

name:	motif58_CGGNAT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:2000465	regulation of glycogen (starch) synthase activity	2.560208e-10
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	2.533555e-9
GO:0006414	translational elongation	4.321773e-9
GO:0016032	viral reproduction	6.308620e-9
GO:0006369	termination of RNA polymerase II transcription	1.487240e-8
GO:0046628	positive regulation of insulin receptor signaling pathway	1.728920e-8
GO:0014057	positive regulation of acetylcholine secretion	4.714360e-8
GO:0048143	astrocyte activation	4.979486e-8
GO:0050434	positive regulation of viral transcription	8.132806e-8
GO:0006353	transcription termination, DNA-dependent	1.439171e-7
GO:0046782	regulation of viral transcription	1.723801e-7
GO:0006415	translational termination	1.849412e-7
GO:0032790	ribosome disassembly	2.220130e-7
GO:2000378	negative regulation of reactive oxygen species metabolic process	2.367296e-7
GO:0019083	viral transcription	5.402517e-7
GO:0044258	intestinal lipid catabolic process	7.775215e-7
GO:0018350	protein esterification	7.775215e-7
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.823945e-7
GO:0015820	leucine transport	8.526112e-7
GO:0035356	cellular triglyceride homeostasis	1.008223e-6
GO:0014056	regulation of acetylcholine secretion	1.757019e-6
GO:0006283	transcription-coupled nucleotide-excision repair	1.865622e-6
GO:0006370	mRNA capping	3.088575e-6
GO:0009452	RNA capping	3.208213e-6
GO:0008033	tRNA processing	3.809284e-6
GO:0006102	isocitrate metabolic process	4.154322e-6
GO:0046626	regulation of insulin receptor signaling pathway	5.174270e-6
GO:0031017	exocrine pancreas development	5.386896e-6
GO:0007140	male meiosis	5.693234e-6
GO:0045725	positive regulation of glycogen biosynthetic process	5.839122e-6
GO:0006289	nucleotide-excision repair	6.038255e-6
GO:2000466	negative regulation of glycogen (starch) synthase activity	7.081697e-6
GO:0009650	UV protection	7.478181e-6
GO:0010626	negative regulation of Schwann cell proliferation	8.639595e-6
GO:0021591	ventricular system development	1.070165e-5
GO:0034633	retinol transport	1.295361e-5
GO:0030853	negative regulation of granulocyte differentiation	1.565864e-5
GO:0031064	negative regulation of histone deacetylation	1.658980e-5
GO:0046521	sphingoid catabolic process	1.691197e-5
GO:0051534	negative regulation of NFAT protein import into nucleus	1.730921e-5
GO:0048524	positive regulation of viral reproduction	1.784349e-5
GO:0006412	translation	1.821585e-5
GO:0048102	autophagic cell death	2.089188e-5
GO:0006368	transcription elongation from RNA polymerase II promoter	2.273361e-5
GO:0008588	release of cytoplasmic sequestered NF-kappaB	2.577305e-5
GO:0007141	male meiosis I	2.758859e-5
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	2.835060e-5
GO:0034623	cellular macromolecular complex disassembly	2.901680e-5
GO:0032984	macromolecular complex disassembly	2.997680e-5
GO:0031643	positive regulation of myelination	3.106154e-5
GO:0030823	regulation of cGMP metabolic process	3.192155e-5
GO:0016071	mRNA metabolic process	3.518600e-5
GO:0042946	glucoside transport	4.516616e-5
GO:0006396	RNA processing	4.965297e-5
GO:0030825	positive regulation of cGMP metabolic process	5.061599e-5
GO:0043624	cellular protein complex disassembly	5.173111e-5
GO:0010509	polyamine homeostasis	5.258169e-5
GO:0043241	protein complex disassembly	5.454029e-5
GO:0040040	thermosensory behavior	5.891931e-5
GO:0006103	2-oxoglutarate metabolic process	6.325516e-5
GO:0034619	cellular chaperone-mediated protein complex assembly	6.496088e-5
GO:0021670	lateral ventricle development	6.547530e-5
GO:0000389	nuclear mRNA 3'-splice site recognition	6.576428e-5
GO:0070875	positive regulation of glycogen metabolic process	6.649022e-5
GO:0003417	growth plate cartilage development	7.047730e-5
GO:0006366	transcription from RNA polymerase II promoter	7.161073e-5
GO:0061360	optic chiasma development	7.634015e-5
GO:2000597	positive regulation of optic nerve formation	7.634015e-5
GO:0021650	vestibulocochlear nerve formation	7.634015e-5
GO:0021633	optic nerve structural organization	7.634015e-5
GO:0035799	ureter maturation	7.634015e-5
GO:0043486	histone exchange	7.638119e-5
GO:0046543	development of secondary female sexual characteristics	7.811716e-5
GO:0045136	development of secondary sexual characteristics	7.902127e-5
GO:0030237	female sex determination	7.922918e-5
GO:0035928	rRNA import into mitochondrion	8.299133e-5
GO:0003406	retinal pigment epithelium development	9.124586e-5
GO:0009062	fatty acid catabolic process	9.831125e-5
GO:0002072	optic cup morphogenesis involved in camera-type eye development	1.002544e-4
GO:0030213	hyaluronan biosynthetic process	1.020481e-4
GO:0033083	regulation of immature T cell proliferation	1.076975e-4
GO:0000080	G1 phase of mitotic cell cycle	1.184465e-4
GO:0019058	viral infectious cycle	1.240095e-4
GO:0021603	cranial nerve formation	1.256598e-4
GO:0000731	DNA synthesis involved in DNA repair	1.256598e-4
GO:0046395	carboxylic acid catabolic process	1.296995e-4
GO:0046778	modification by virus of host mRNA processing	1.297344e-4
GO:0009440	cyanate catabolic process	1.297344e-4
GO:0034470	ncRNA processing	1.319266e-4
GO:0072329	monocarboxylic acid catabolic process	1.329088e-4
GO:0032312	regulation of ARF GTPase activity	1.390406e-4
GO:0043585	nose morphogenesis	1.468022e-4
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.469247e-4
GO:0030157	pancreatic juice secretion	1.479860e-4
GO:0000375	RNA splicing, via transesterification reactions	1.494113e-4
GO:0032863	activation of Rac GTPase activity	1.552920e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	1.578610e-4
GO:0032230	positive regulation of synaptic transmission, GABAergic	1.586679e-4
GO:0070253	somatostatin secretion	1.591463e-4
GO:0032812	positive regulation of epinephrine secretion	1.591463e-4
GO:0018293	protein-FAD linkage	1.646623e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.646623e-4
GO:0032988	ribonucleoprotein complex disassembly	1.658595e-4
GO:0006383	transcription from RNA polymerase III promoter	1.736067e-4
GO:0035815	positive regulation of renal sodium excretion	1.822288e-4
GO:0005979	regulation of glycogen biosynthetic process	1.826284e-4
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.840030e-4
GO:0019303	D-ribose catabolic process	2.006826e-4
GO:0043171	peptide catabolic process	2.153480e-4
GO:0043044	ATP-dependent chromatin remodeling	2.155910e-4
GO:0060253	negative regulation of glial cell proliferation	2.170092e-4
GO:0031914	negative regulation of synaptic plasticity	2.218940e-4
GO:0061054	dermatome development	2.301068e-4
GO:0030178	negative regulation of Wnt receptor signaling pathway	2.301513e-4
GO:0007288	sperm axoneme assembly	2.347550e-4
GO:0031018	endocrine pancreas development	2.447462e-4
GO:0006458	'de novo' protein folding	2.476082e-4
GO:0050432	catecholamine secretion	2.594660e-4
GO:0060356	leucine import	2.732263e-4
GO:2000009	negative regulation of protein localization at cell surface	2.788525e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.957438e-4
GO:0009296	flagellum assembly	3.050274e-4
GO:0042762	regulation of sulfur metabolic process	3.062487e-4
GO:0003329	pancreatic PP cell fate commitment	3.074411e-4
GO:0003326	pancreatic A cell fate commitment	3.074411e-4
GO:0046514	ceramide catabolic process	3.094446e-4
GO:0000154	rRNA modification	3.159328e-4
GO:0034389	lipid particle organization	3.387175e-4
GO:0006930	substrate-dependent cell migration, cell extension	3.418246e-4
GO:0006398	histone mRNA 3'-end processing	3.597948e-4
GO:0051029	rRNA transport	3.712884e-4
GO:0034111	negative regulation of homotypic cell-cell adhesion	3.712884e-4
GO:0043381	negative regulation of memory T cell differentiation	3.773086e-4
GO:0043538	regulation of actin phosphorylation	3.773086e-4
GO:0006409	tRNA export from nucleus	3.895610e-4
GO:0010954	positive regulation of protein processing	4.163545e-4
GO:0035621	ER to Golgi ceramide transport	4.234481e-4
GO:0072553	terminal button organization	4.234481e-4
GO:0033084	regulation of immature T cell proliferation in thymus	4.244477e-4
GO:0051176	positive regulation of sulfur metabolic process	4.351064e-4
GO:0045040	protein import into mitochondrial outer membrane	4.440934e-4
GO:0032228	regulation of synaptic transmission, GABAergic	4.547167e-4
GO:0001886	endothelial cell morphogenesis	4.581503e-4
GO:0042797	tRNA transcription from RNA polymerase III promoter	4.978954e-4
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	4.978954e-4
GO:0035090	maintenance of apical/basal cell polarity	4.992308e-4
GO:0015853	adenine transport	5.310581e-4
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.391027e-4
GO:0045199	maintenance of epithelial cell apical/basal polarity	5.671407e-4
GO:0030208	dermatan sulfate biosynthetic process	5.671407e-4
GO:0006772	thiamine metabolic process	5.884144e-4
GO:0035411	catenin import into nucleus	6.115041e-4
GO:0032855	positive regulation of Rac GTPase activity	6.126914e-4
GO:0030852	regulation of granulocyte differentiation	6.162972e-4
GO:0090103	cochlea morphogenesis	6.289009e-4
GO:0061037	negative regulation of cartilage development	6.344606e-4
GO:0002679	respiratory burst involved in defense response	6.352834e-4
GO:0015886	heme transport	6.352834e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	6.404675e-4
GO:0014819	regulation of skeletal muscle contraction	6.515245e-4
GO:0007023	post-chaperonin tubulin folding pathway	6.515245e-4
GO:0072300	positive regulation of metanephric glomerulus development	6.702148e-4
GO:0071897	DNA biosynthetic process	6.825963e-4
GO:0031558	induction of apoptosis in response to chemical stimulus	6.871621e-4
GO:0006399	tRNA metabolic process	7.468683e-4
GO:0006635	fatty acid beta-oxidation	7.539795e-4
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	7.595230e-4
GO:0042254	ribosome biogenesis	7.706104e-4
GO:0006097	glyoxylate cycle	7.851461e-4
GO:0009301	snRNA transcription	7.930164e-4
GO:0021932	hindbrain radial glia guided cell migration	8.278973e-4
GO:0032674	regulation of interleukin-5 production	8.398535e-4
GO:0045655	regulation of monocyte differentiation	8.554140e-4
GO:0031055	chromatin remodeling at centromere	8.578218e-4
GO:0033260	DNA replication involved in S phase	8.630683e-4
GO:0042450	arginine biosynthetic process via ornithine	8.630683e-4
GO:0031118	rRNA pseudouridine synthesis	8.630683e-4
GO:0008049	male courtship behavior	8.630683e-4
GO:0010734	negative regulation of protein glutathionylation	8.630683e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	8.630683e-4
GO:0001957	intramembranous ossification	8.834371e-4
GO:0021562	vestibulocochlear nerve development	8.882302e-4
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	9.170239e-4
GO:0070873	regulation of glycogen metabolic process	9.424392e-4
GO:0021559	trigeminal nerve development	9.632101e-4
GO:0021526	medial motor column neuron differentiation	1.016294e-3
GO:0010756	positive regulation of plasminogen activation	1.062215e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	1.076181e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	1.083626e-3
GO:0001970	positive regulation of activation of membrane attack complex	1.091126e-3
GO:0009304	tRNA transcription	1.098588e-3
GO:0043491	protein kinase B signaling cascade	1.123290e-3
GO:0014044	Schwann cell development	1.154633e-3
GO:0051084	'de novo' posttranslational protein folding	1.157539e-3
GO:0002121	inter-male aggressive behavior	1.162987e-3
GO:0048069	eye pigmentation	1.165699e-3
GO:0014020	primary neural tube formation	1.173391e-3
GO:0006457	protein folding	1.174708e-3
GO:0043064	flagellum organization	1.183395e-3
GO:0034498	early endosome to Golgi transport	1.184524e-3
GO:0048313	Golgi inheritance	1.184524e-3
GO:0006612	protein targeting to membrane	1.184765e-3
GO:0032754	positive regulation of interleukin-5 production	1.243159e-3
GO:0002149	hypochlorous acid biosynthetic process	1.255896e-3
GO:0032714	negative regulation of interleukin-5 production	1.296513e-3
GO:0002074	extraocular skeletal muscle development	1.317312e-3
GO:0034259	negative regulation of Rho GTPase activity	1.317312e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.317312e-3
GO:0072162	metanephric mesenchymal cell differentiation	1.318864e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	1.326948e-3
GO:0016264	gap junction assembly	1.420839e-3
GO:0042703	menstruation	1.471683e-3
GO:0019101	female somatic sex determination	1.471683e-3
GO:0042375	quinone cofactor metabolic process	1.492657e-3
GO:0044240	multicellular organismal lipid catabolic process	1.495073e-3
GO:0051457	maintenance of protein location in nucleus	1.512755e-3
GO:0006349	regulation of gene expression by genetic imprinting	1.545177e-3
GO:0060707	trophoblast giant cell differentiation	1.574721e-3
GO:0051318	G1 phase	1.585760e-3
GO:0060816	random inactivation of X chromosome	1.676216e-3
GO:0050666	regulation of homocysteine metabolic process	1.679276e-3
GO:0016140	O-glycoside metabolic process	1.679276e-3
GO:0042723	thiamine-containing compound metabolic process	1.752526e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.758095e-3
GO:0070194	synaptonemal complex disassembly	1.758095e-3
GO:0019448	L-cysteine catabolic process	1.758095e-3
GO:0006707	cholesterol catabolic process	1.762582e-3
GO:0001843	neural tube closure	1.784283e-3
GO:0009060	aerobic respiration	1.785091e-3
GO:0016142	O-glycoside catabolic process	1.799237e-3
GO:0006308	DNA catabolic process	1.832278e-3
GO:0044282	small molecule catabolic process	1.865351e-3
GO:0043921	modulation by host of viral transcription	1.876813e-3
GO:0040020	regulation of meiosis	1.886436e-3
GO:0035566	regulation of metanephros size	1.958247e-3
GO:0001778	plasma membrane repair	2.036233e-3
GO:0019556	histidine catabolic process to glutamate and formamide	2.036271e-3
GO:0008272	sulfate transport	2.154871e-3
GO:0021592	fourth ventricle development	2.183800e-3
GO:0003309	type B pancreatic cell differentiation	2.212420e-3
GO:0043114	regulation of vascular permeability	2.215894e-3
GO:0007006	mitochondrial membrane organization	2.227961e-3
GO:0031016	pancreas development	2.269540e-3
GO:0051567	histone H3-K9 methylation	2.280833e-3
GO:0043088	regulation of Cdc42 GTPase activity	2.287745e-3
GO:0003416	endochondral bone growth	2.301751e-3
GO:0021523	somatic motor neuron differentiation	2.316051e-3
GO:0090150	establishment of protein localization in membrane	2.316051e-3
GO:0045963	negative regulation of dopamine metabolic process	2.342858e-3
GO:0050668	positive regulation of homocysteine metabolic process	2.342858e-3
GO:0035445	borate transmembrane transport	2.342858e-3
GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	2.342858e-3
GO:0072595	maintenance of protein localization to organelle	2.350850e-3
GO:0042363	fat-soluble vitamin catabolic process	2.355590e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	2.377242e-3
GO:0001963	synaptic transmission, dopaminergic	2.378349e-3
GO:0010070	zygote asymmetric cell division	2.392971e-3
GO:0009451	RNA modification	2.411344e-3
GO:0060349	bone morphogenesis	2.419544e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	2.444060e-3
GO:0001956	positive regulation of neurotransmitter secretion	2.518563e-3
GO:0001514	selenocysteine incorporation	2.518563e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	2.524726e-3
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	2.533825e-3
GO:0030322	stabilization of membrane potential	2.548308e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.591994e-3
GO:0060606	tube closure	2.603732e-3
GO:0018993	somatic sex determination	2.686704e-3
GO:0010890	positive regulation of sequestering of triglyceride	2.686704e-3
GO:0001757	somite specification	2.732237e-3
GO:0071899	negative regulation of estrogen receptor binding	2.743616e-3
GO:0072201	negative regulation of mesenchymal cell proliferation	2.822989e-3
GO:0006235	dTTP biosynthetic process	3.175026e-3
GO:0000088	mitotic prophase	3.175026e-3
GO:0006281	DNA repair	3.187843e-3
GO:0048708	astrocyte differentiation	3.248429e-3
GO:0030091	protein repair	3.308602e-3
GO:0060708	spongiotrophoblast differentiation	3.313400e-3
GO:0021943	formation of radial glial scaffolds	3.342953e-3
GO:0070245	positive regulation of thymocyte apoptosis	3.350424e-3
GO:0002066	columnar/cuboidal epithelial cell development	3.471363e-3
GO:0006364	rRNA processing	3.542117e-3
GO:0051131	chaperone-mediated protein complex assembly	3.604451e-3
GO:0006354	transcription elongation, DNA-dependent	3.605593e-3
GO:0042373	vitamin K metabolic process	3.620853e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	3.620853e-3
GO:2000273	positive regulation of receptor activity	3.637647e-3
GO:0043973	histone H3-K4 acetylation	3.666939e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.666939e-3
GO:0043418	homocysteine catabolic process	3.666939e-3
GO:0006535	cysteine biosynthetic process from serine	3.666939e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.666939e-3
GO:0019343	cysteine biosynthetic process via cystathionine	3.666939e-3
GO:0019346	transsulfuration	3.666939e-3
GO:0051965	positive regulation of synapse assembly	3.798162e-3
GO:0032288	myelin assembly	3.804657e-3
GO:0000012	single strand break repair	3.814695e-3
GO:0034959	endothelin maturation	3.818105e-3
GO:0010814	substance P catabolic process	3.818105e-3
GO:0010816	calcitonin catabolic process	3.818105e-3
GO:0010815	bradykinin catabolic process	3.848444e-3
GO:0016226	iron-sulfur cluster assembly	3.880309e-3
GO:0016048	detection of temperature stimulus	3.981468e-3
GO:0021535	cell migration in hindbrain	3.992981e-3
GO:0060056	mammary gland involution	4.039194e-3
GO:0045063	T-helper 1 cell differentiation	4.047163e-3
GO:0070831	basement membrane assembly	4.055689e-3
GO:0035646	endosome to melanosome transport	4.055689e-3
GO:0030683	evasion by virus of host immune response	4.055689e-3
GO:0045606	positive regulation of epidermal cell differentiation	4.222365e-3
GO:0071514	genetic imprinting	4.239023e-3
GO:0034660	ncRNA metabolic process	4.289876e-3
GO:0045343	regulation of MHC class I biosynthetic process	4.329382e-3
GO:0051445	regulation of meiotic cell cycle	4.450819e-3
GO:0010821	regulation of mitochondrion organization	4.463430e-3
GO:0046380	N-acetylneuraminate biosynthetic process	4.470944e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	4.470944e-3
GO:0016078	tRNA catabolic process	4.470944e-3
GO:0001682	tRNA 5'-leader removal	4.470944e-3
GO:0072668	tubulin complex biogenesis	4.484489e-3
GO:0055026	negative regulation of cardiac muscle tissue development	4.537521e-3
GO:0043570	maintenance of DNA repeat elements	4.598789e-3
GO:0033091	positive regulation of immature T cell proliferation	4.598789e-3
GO:0060689	cell differentiation involved in salivary gland development	4.709692e-3
GO:0001510	RNA methylation	4.789286e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	4.798655e-3
GO:0045409	negative regulation of interleukin-6 biosynthetic process	4.841376e-3
GO:2000077	negative regulation of type B pancreatic cell development	4.879112e-3
GO:0006422	aspartyl-tRNA aminoacylation	4.963485e-3
GO:0007339	binding of sperm to zona pellucida	4.980596e-3
GO:0007007	inner mitochondrial membrane organization	5.121094e-3
GO:0032107	regulation of response to nutrient levels	5.122115e-3
GO:0061384	heart trabecular morphogenesis	5.170921e-3
GO:0035922	foramen ovale closure	5.204853e-3
GO:0060577	pulmonary vein morphogenesis	5.204853e-3
GO:0003193	pulmonary valve formation	5.204853e-3
GO:0000354	cis assembly of pre-catalytic spliceosome	5.204853e-3
GO:0048703	embryonic viscerocranium morphogenesis	5.376634e-3
GO:0051187	cofactor catabolic process	5.439778e-3
GO:0008065	establishment of blood-nerve barrier	5.490247e-3
GO:0002071	glandular epithelial cell maturation	5.490247e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	5.496343e-3
GO:0045657	positive regulation of monocyte differentiation	5.526952e-3
GO:0021678	third ventricle development	5.631856e-3
GO:0045719	negative regulation of glycogen biosynthetic process	5.673295e-3
GO:0032656	regulation of interleukin-13 production	5.795642e-3
GO:0003344	pericardium morphogenesis	5.858073e-3
GO:0032696	negative regulation of interleukin-13 production	5.863814e-3
GO:0043923	positive regulation by host of viral transcription	5.922590e-3
GO:0007263	nitric oxide mediated signal transduction	6.026236e-3
GO:0060347	heart trabecula formation	6.029557e-3
GO:0051881	regulation of mitochondrial membrane potential	6.109305e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	6.209422e-3
GO:0048103	somatic stem cell division	6.239644e-3
GO:0048821	erythrocyte development	6.280878e-3
GO:0032736	positive regulation of interleukin-13 production	6.291002e-3
GO:0060157	urinary bladder development	6.393375e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	6.410188e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	6.483082e-3
GO:0060580	ventral spinal cord interneuron fate determination	6.551789e-3
GO:0003327	type B pancreatic cell fate commitment	6.551789e-3
GO:0033484	nitric oxide homeostasis	6.668423e-3
GO:0019054	modulation by virus of host cellular process	6.754329e-3
GO:0006863	purine base transport	6.754329e-3
GO:0090193	positive regulation of glomerulus development	6.842156e-3
GO:0030223	neutrophil differentiation	6.882081e-3
GO:0034214	protein hexamerization	6.994868e-3
GO:0016072	rRNA metabolic process	7.050388e-3
GO:0090037	positive regulation of protein kinase C signaling cascade	7.057282e-3
GO:0019395	fatty acid oxidation	7.112773e-3
GO:0045200	establishment of neuroblast polarity	7.184079e-3
GO:0070368	positive regulation of hepatocyte differentiation	7.184079e-3
GO:0003310	pancreatic A cell differentiation	7.405260e-3
GO:0006361	transcription initiation from RNA polymerase I promoter	7.484408e-3
GO:0042989	sequestering of actin monomers	7.510934e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	7.693570e-3
GO:2000035	regulation of stem cell division	7.915410e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	8.000538e-3
GO:0021589	cerebellum structural organization	8.043661e-3
GO:0060904	regulation of protein folding in endoplasmic reticulum	8.043661e-3
GO:0035024	negative regulation of Rho protein signal transduction	8.087168e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	8.292905e-3
GO:0032717	negative regulation of interleukin-8 production	8.292905e-3
GO:0045658	regulation of neutrophil differentiation	8.428686e-3
GO:0009450	gamma-aminobutyric acid catabolic process	8.446790e-3
GO:0071425	hemopoietic stem cell proliferation	8.474720e-3
GO:0090002	establishment of protein localization in plasma membrane	8.596594e-3
GO:0070366	regulation of hepatocyte differentiation	8.631198e-3
GO:0000028	ribosomal small subunit assembly	8.771554e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	8.857425e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	8.867773e-3
GO:0051001	negative regulation of nitric-oxide synthase activity	8.908914e-3
GO:0046426	negative regulation of JAK-STAT cascade	8.917518e-3
GO:0032095	regulation of response to food	9.026306e-3
GO:0009109	coenzyme catabolic process	9.060382e-3
GO:0003100	regulation of systemic arterial blood pressure by endothelin	9.164069e-3
GO:0042538	hyperosmotic salinity response	9.168109e-3
GO:0044089	positive regulation of cellular component biogenesis	9.256021e-3
GO:0031063	regulation of histone deacetylation	9.256021e-3
GO:0043400	cortisol secretion	9.281445e-3
GO:0031275	regulation of lateral pseudopodium assembly	9.281445e-3
GO:0002572	pro-T cell differentiation	9.281445e-3
GO:0043922	negative regulation by host of viral transcription	9.282362e-3
GO:0010520	regulation of reciprocal meiotic recombination	9.484096e-3
GO:0043308	eosinophil degranulation	9.697473e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	9.697473e-3
GO:0007341	penetration of zona pellucida	9.846153e-3
GO:0018198	peptidyl-cysteine modification	9.874392e-3
GO:0032801	receptor catabolic process	9.911046e-3
GO:0060026	convergent extension	9.917935e-3
GO:0003065	positive regulation of heart rate by epinephrine	9.978304e-3
GO:0044062	regulation of excretion	9.992815e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.019925e-2
GO:0018023	peptidyl-lysine trimethylation	1.021658e-2
GO:0060744	mammary gland branching involved in thelarche	1.024395e-2
GO:0070234	positive regulation of T cell apoptosis	1.031763e-2
GO:0046621	negative regulation of organ growth	1.031763e-2
GO:0021506	anterior neuropore closure	1.042728e-2
GO:0014916	regulation of lung blood pressure	1.042728e-2
GO:0000266	mitochondrial fission	1.055072e-2
GO:0003062	regulation of heart rate by chemical signal	1.067130e-2
GO:0015780	nucleotide-sugar transport	1.072130e-2
GO:0071335	hair follicle cell proliferation	1.104622e-2
GO:0032290	peripheral nervous system myelin formation	1.104622e-2
GO:0019323	pentose catabolic process	1.104622e-2
GO:0051594	detection of glucose	1.106559e-2
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	1.114820e-2
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	1.114820e-2
GO:0000239	pachytene	1.116043e-2
GO:0060376	positive regulation of mast cell differentiation	1.117437e-2
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	1.117437e-2
GO:0032469	endoplasmic reticulum calcium ion homeostasis	1.127732e-2
GO:0015696	ammonium transport	1.140920e-2
GO:0007127	meiosis I	1.149902e-2
GO:0090344	negative regulation of cell aging	1.159831e-2
GO:0006397	mRNA processing	1.177440e-2
GO:0048861	leukemia inhibitory factor signaling pathway	1.181275e-2
GO:0060299	negative regulation of sarcomere organization	1.184420e-2
GO:0033292	T-tubule organization	1.184420e-2
GO:0046491	L-methylmalonyl-CoA metabolic process	1.184420e-2
GO:0030851	granulocyte differentiation	1.188948e-2
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.194075e-2
GO:0016559	peroxisome fission	1.194075e-2
GO:0014028	notochord formation	1.194075e-2
GO:0003184	pulmonary valve morphogenesis	1.194075e-2
GO:0070544	histone H3-K36 demethylation	1.200566e-2
GO:0022011	myelination in peripheral nervous system	1.201225e-2
GO:0003148	outflow tract septum morphogenesis	1.224328e-2
GO:0060041	retina development in camera-type eye	1.226092e-2
GO:0090140	regulation of mitochondrial fission	1.226200e-2
GO:0031167	rRNA methylation	1.226200e-2
GO:0060711	labyrinthine layer development	1.231267e-2
GO:0006261	DNA-dependent DNA replication	1.232816e-2
GO:0035813	regulation of renal sodium excretion	1.267282e-2
GO:0031557	induction of programmed cell death in response to chemical stimulus	1.272906e-2
GO:0042104	positive regulation of activated T cell proliferation	1.273710e-2
GO:0003323	type B pancreatic cell development	1.282063e-2
GO:0021623	oculomotor nerve formation	1.299943e-2
GO:0003409	optic cup structural organization	1.299943e-2
GO:0003404	optic vesicle morphogenesis	1.299943e-2
GO:0031134	sister chromatid biorientation	1.304120e-2
GO:0006423	cysteinyl-tRNA aminoacylation	1.304120e-2
GO:0035036	sperm-egg recognition	1.309895e-2
GO:0006297	nucleotide-excision repair, DNA gap filling	1.326024e-2
GO:0071895	odontoblast differentiation	1.345242e-2
GO:0003188	heart valve formation	1.351142e-2
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	1.358213e-2
GO:0034440	lipid oxidation	1.384545e-2
GO:0032926	negative regulation of activin receptor signaling pathway	1.413143e-2
GO:0048242	epinephrine secretion	1.423867e-2
GO:0016973	poly(A)+ mRNA export from nucleus	1.425876e-2
GO:0007340	acrosome reaction	1.435916e-2
GO:0035112	genitalia morphogenesis	1.439753e-2
GO:0006534	cysteine metabolic process	1.441663e-2
GO:0002829	negative regulation of type 2 immune response	1.441663e-2
GO:0006914	autophagy	1.456094e-2
GO:0043631	RNA polyadenylation	1.473872e-2
GO:0035082	axoneme assembly	1.492400e-2
GO:0006548	histidine catabolic process	1.494760e-2
GO:0010845	positive regulation of reciprocal meiotic recombination	1.498436e-2
GO:0035883	enteroendocrine cell differentiation	1.498436e-2
GO:0060611	mammary gland fat development	1.503545e-2
GO:0007020	microtubule nucleation	1.510852e-2
GO:0034110	regulation of homotypic cell-cell adhesion	1.525845e-2
GO:0045836	positive regulation of meiosis	1.545872e-2
GO:0010907	positive regulation of glucose metabolic process	1.567010e-2
GO:0035121	tail morphogenesis	1.585703e-2
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.585860e-2
GO:0051593	response to folic acid	1.595326e-2
GO:0016446	somatic hypermutation of immunoglobulin genes	1.606378e-2
GO:0006378	mRNA polyadenylation	1.611844e-2
GO:0045947	negative regulation of translational initiation	1.635085e-2
GO:0048793	pronephros development	1.637015e-2
GO:0015709	thiosulfate transport	1.652662e-2
GO:0071423	malate transmembrane transport	1.652662e-2
GO:0048291	isotype switching to IgG isotypes	1.652662e-2
GO:0010760	negative regulation of macrophage chemotaxis	1.652662e-2
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.652662e-2
GO:0002368	B cell cytokine production	1.652662e-2
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.653442e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0031577	spindle checkpoint	7.100880e-9
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.347315e-8
GO:0007099	centriole replication	2.691364e-8
GO:0071174	mitotic cell cycle spindle checkpoint	1.750573e-7
GO:0006397	mRNA processing	2.162021e-7
GO:0071173	spindle assembly checkpoint	2.490136e-7
GO:0033344	cholesterol efflux	2.816096e-7
GO:0051298	centrosome duplication	3.700037e-7
GO:0034442	regulation of lipoprotein oxidation	3.761026e-7
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	5.182475e-7
GO:0007094	mitotic cell cycle spindle assembly checkpoint	5.470243e-7
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.200662e-6
GO:0008380	RNA splicing	1.324337e-6
GO:0006260	DNA replication	1.392148e-6
GO:0033239	negative regulation of cellular amine metabolic process	1.404418e-6
GO:2000078	positive regulation of type B pancreatic cell development	1.831104e-6
GO:0035928	rRNA import into mitochondrion	1.831104e-6
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.236555e-6
GO:0032374	regulation of cholesterol transport	3.640968e-6
GO:0010900	negative regulation of phosphatidylcholine catabolic process	6.752776e-6
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	9.832160e-6
GO:0060299	negative regulation of sarcomere organization	9.832160e-6
GO:0043691	reverse cholesterol transport	1.079953e-5
GO:0033700	phospholipid efflux	1.079953e-5
GO:0034447	very-low-density lipoprotein particle clearance	1.783147e-5
GO:0000279	M phase	1.789297e-5
GO:0043457	regulation of cellular respiration	1.844125e-5
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.982710e-5
GO:0050748	negative regulation of lipoprotein metabolic process	2.002573e-5
GO:0006396	RNA processing	2.130126e-5
GO:0061181	regulation of chondrocyte development	2.151427e-5
GO:0032048	cardiolipin metabolic process	2.158678e-5
GO:0042697	menopause	2.963307e-5
GO:0071827	plasma lipoprotein particle organization	3.779367e-5
GO:0006476	protein deacetylation	3.961542e-5
GO:0007141	male meiosis I	4.245871e-5
GO:0042254	ribosome biogenesis	5.227668e-5
GO:0006982	response to lipid hydroperoxide	5.559580e-5
GO:0045647	negative regulation of erythrocyte differentiation	5.833147e-5
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	5.847458e-5
GO:0060217	hemangioblast cell differentiation	5.847458e-5
GO:0045799	positive regulation of chromatin assembly or disassembly	5.847458e-5
GO:0022417	protein maturation by protein folding	5.847458e-5
GO:0090343	positive regulation of cell aging	6.712054e-5
GO:0032368	regulation of lipid transport	7.286967e-5
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	7.504010e-5
GO:0035601	protein deacylation	7.915329e-5
GO:0051004	regulation of lipoprotein lipase activity	8.588391e-5
GO:0000305	response to oxygen radical	8.681979e-5
GO:0032049	cardiolipin biosynthetic process	9.125741e-5
GO:0031397	negative regulation of protein ubiquitination	9.363643e-5
GO:0046958	nonassociative learning	9.372165e-5
GO:0006302	double-strand break repair	9.814183e-5
GO:0045919	positive regulation of cytolysis	1.123465e-4
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	1.123465e-4
GO:0040040	thermosensory behavior	1.123465e-4
GO:0007067	mitosis	1.144547e-4
GO:0022403	cell cycle phase	1.207438e-4
GO:0072560	type B pancreatic cell maturation	1.324701e-4
GO:0033037	polysaccharide localization	1.357915e-4
GO:0050746	regulation of lipoprotein metabolic process	1.385428e-4
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.395515e-4
GO:0000087	M phase of mitotic cell cycle	1.493093e-4
GO:0061084	negative regulation of protein refolding	1.559279e-4
GO:0048285	organelle fission	1.609310e-4
GO:0055090	acylglycerol homeostasis	1.645052e-4
GO:0034369	plasma lipoprotein particle remodeling	1.708401e-4
GO:0007127	meiosis I	1.753323e-4
GO:0001579	medium-chain fatty acid transport	2.070683e-4
GO:0042157	lipoprotein metabolic process	2.091662e-4
GO:0019430	removal of superoxide radicals	2.113066e-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.131289e-4
GO:0070172	positive regulation of tooth mineralization	2.182061e-4
GO:0015920	lipopolysaccharide transport	2.196708e-4
GO:0090398	cellular senescence	2.210900e-4
GO:0060136	embryonic process involved in female pregnancy	2.309419e-4
GO:0007144	female meiosis I	2.380232e-4
GO:0060696	regulation of phospholipid catabolic process	2.453270e-4
GO:0046984	regulation of hemoglobin biosynthetic process	2.499301e-4
GO:0006235	dTTP biosynthetic process	2.697936e-4
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.697936e-4
GO:2000774	positive regulation of cellular senescence	3.038363e-4
GO:0090402	oncogene-induced senescence	3.038363e-4
GO:0035986	senescence-associated heterochromatin focus formation	3.038363e-4
GO:0007093	mitotic cell cycle checkpoint	3.175042e-4
GO:0006403	RNA localization	3.471088e-4
GO:0032532	regulation of microvillus length	3.488032e-4
GO:0060005	vestibular reflex	3.493065e-4
GO:0000303	response to superoxide	3.860243e-4
GO:0031334	positive regulation of protein complex assembly	3.862936e-4
GO:0006805	xenobiotic metabolic process	3.884051e-4
GO:0071711	basement membrane organization	3.921759e-4
GO:0006611	protein export from nucleus	3.981131e-4
GO:0097006	regulation of plasma lipoprotein particle levels	4.262929e-4
GO:0031507	heterochromatin formation	4.649294e-4
GO:0050684	regulation of mRNA processing	4.694866e-4
GO:0007098	centrosome cycle	4.697507e-4
GO:0060993	kidney morphogenesis	4.933822e-4
GO:0001935	endothelial cell proliferation	4.966010e-4
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	4.978738e-4
GO:0046314	phosphocreatine biosynthetic process	5.033153e-4
GO:0051865	protein autoubiquitination	5.070217e-4
GO:0043243	positive regulation of protein complex disassembly	5.411768e-4
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	5.439857e-4
GO:0043570	maintenance of DNA repeat elements	5.557299e-4
GO:0051725	protein de-ADP-ribosylation	5.656402e-4
GO:0043254	regulation of protein complex assembly	5.793126e-4
GO:0090161	Golgi ribbon formation	5.835010e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	5.835010e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	5.914937e-4
GO:0032530	regulation of microvillus organization	6.108237e-4
GO:0033211	adiponectin-mediated signaling pathway	6.152172e-4
GO:0006913	nucleocytoplasmic transport	6.179724e-4
GO:0051276	chromosome organization	6.192041e-4
GO:0003065	positive regulation of heart rate by epinephrine	6.197548e-4
GO:0046902	regulation of mitochondrial membrane permeability	6.666768e-4
GO:0046092	deoxycytidine metabolic process	6.854770e-4
GO:0060534	trachea cartilage development	6.936868e-4
GO:0033238	regulation of cellular amine metabolic process	6.960971e-4
GO:0031116	positive regulation of microtubule polymerization	7.056531e-4
GO:0016071	mRNA metabolic process	7.139441e-4
GO:0006281	DNA repair	7.372853e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	7.444416e-4
GO:0046605	regulation of centrosome cycle	7.723057e-4
GO:0032271	regulation of protein polymerization	7.847886e-4
GO:0007129	synapsis	8.657930e-4
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	8.779121e-4
GO:0046853	inositol or phosphatidylinositol phosphorylation	8.779121e-4
GO:0032226	positive regulation of synaptic transmission, dopaminergic	8.779121e-4
GO:0071316	cellular response to nicotine	9.784361e-4
GO:0002227	innate immune response in mucosa	9.859373e-4
GO:0032423	regulation of mismatch repair	1.015055e-3
GO:0060669	embryonic placenta morphogenesis	1.050037e-3
GO:0035414	negative regulation of catenin import into nucleus	1.058164e-3
GO:0061156	pulmonary artery morphogenesis	1.066485e-3
GO:0051956	negative regulation of amino acid transport	1.066485e-3
GO:0031536	positive regulation of exit from mitosis	1.066485e-3
GO:0045837	negative regulation of membrane potential	1.071005e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.072958e-3
GO:0032383	regulation of intracellular cholesterol transport	1.072958e-3
GO:0015939	pantothenate metabolic process	1.072958e-3
GO:0018065	protein-cofactor linkage	1.085440e-3
GO:0051169	nuclear transport	1.104086e-3
GO:0048793	pronephros development	1.120347e-3
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	1.144247e-3
GO:0042743	hydrogen peroxide metabolic process	1.197965e-3
GO:0051299	centrosome separation	1.224343e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.224343e-3
GO:0007063	regulation of sister chromatid cohesion	1.228894e-3
GO:0009082	branched chain family amino acid biosynthetic process	1.271566e-3
GO:0000185	activation of MAPKKK activity	1.271566e-3
GO:0000070	mitotic sister chromatid segregation	1.379628e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.404048e-3
GO:0070192	chromosome organization involved in meiosis	1.425988e-3
GO:0060364	frontal suture morphogenesis	1.438286e-3
GO:0043973	histone H3-K4 acetylation	1.446702e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.446702e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.446702e-3
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	1.446702e-3
GO:0042178	xenobiotic catabolic process	1.501533e-3
GO:0019255	glucose 1-phosphate metabolic process	1.530528e-3
GO:0019218	regulation of steroid metabolic process	1.558881e-3
GO:0045839	negative regulation of mitosis	1.607763e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	1.640937e-3
GO:0030970	retrograde protein transport, ER to cytosol	1.654792e-3
GO:0051798	positive regulation of hair follicle development	1.683077e-3
GO:0018345	protein palmitoylation	1.704808e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	1.714472e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.714472e-3
GO:0065005	protein-lipid complex assembly	1.722556e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.733666e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	1.741491e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.826232e-3
GO:0051340	regulation of ligase activity	1.894442e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.906638e-3
GO:0046890	regulation of lipid biosynthetic process	1.929962e-3
GO:0051983	regulation of chromosome segregation	1.944059e-3
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	1.946604e-3
GO:0043922	negative regulation by host of viral transcription	1.969074e-3
GO:0071624	positive regulation of granulocyte chemotaxis	2.003050e-3
GO:0000085	G2 phase of mitotic cell cycle	2.018826e-3
GO:0050658	RNA transport	2.030542e-3
GO:0043523	regulation of neuron apoptosis	2.035018e-3
GO:0031113	regulation of microtubule polymerization	2.078392e-3
GO:0016032	viral reproduction	2.105309e-3
GO:0090312	positive regulation of protein deacetylation	2.126838e-3
GO:0071843	cellular component biogenesis at cellular level	2.211193e-3
GO:0018394	peptidyl-lysine acetylation	2.238910e-3
GO:0000819	sister chromatid segregation	2.250975e-3
GO:0042769	DNA damage response, detection of DNA damage	2.287320e-3
GO:0035855	megakaryocyte development	2.293460e-3
GO:0007346	regulation of mitotic cell cycle	2.304943e-3
GO:0032897	negative regulation of viral transcription	2.352151e-3
GO:0035802	adrenal cortex formation	2.353426e-3
GO:0072194	kidney smooth muscle tissue development	2.353426e-3
GO:0010948	negative regulation of cell cycle process	2.402244e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	2.405212e-3
GO:0018393	internal peptidyl-lysine acetylation	2.480540e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	2.501218e-3
GO:0018293	protein-FAD linkage	2.516108e-3
GO:0042228	interleukin-8 biosynthetic process	2.516108e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	2.516108e-3
GO:0000379	tRNA-type intron splice site recognition and cleavage	2.516108e-3
GO:0071158	positive regulation of cell cycle arrest	2.614394e-3
GO:0018106	peptidyl-histidine phosphorylation	2.624079e-3
GO:0032508	DNA duplex unwinding	2.811341e-3
GO:0022402	cell cycle process	2.830407e-3
GO:0045940	positive regulation of steroid metabolic process	2.855806e-3
GO:0042304	regulation of fatty acid biosynthetic process	2.870817e-3
GO:0070925	organelle assembly	2.923250e-3
GO:0010467	gene expression	2.942747e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.000285e-3
GO:0060535	trachea cartilage morphogenesis	3.018542e-3
GO:0001970	positive regulation of activation of membrane attack complex	3.018542e-3
GO:0031396	regulation of protein ubiquitination	3.037499e-3
GO:0043244	regulation of protein complex disassembly	3.070021e-3
GO:0033572	transferrin transport	3.070737e-3
GO:0071279	cellular response to cobalt ion	3.108172e-3
GO:0035356	cellular triglyceride homeostasis	3.108172e-3
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.108172e-3
GO:0010637	negative regulation of mitochondrial fusion	3.108172e-3
GO:0032077	positive regulation of deoxyribonuclease activity	3.108172e-3
GO:0032277	negative regulation of gonadotropin secretion	3.172033e-3
GO:0010898	positive regulation of triglyceride catabolic process	3.188591e-3
GO:0072180	mesonephric duct morphogenesis	3.278643e-3
GO:0051915	induction of synaptic plasticity by chemical substance	3.306542e-3
GO:0010824	regulation of centrosome duplication	3.306542e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	3.308581e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	3.380407e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	3.384005e-3
GO:0048389	intermediate mesoderm development	3.384005e-3
GO:0002036	regulation of L-glutamate transport	3.384005e-3
GO:0006172	ADP biosynthetic process	3.384005e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	3.494656e-3
GO:0006438	valyl-tRNA aminoacylation	3.494656e-3
GO:0043543	protein acylation	3.545914e-3
GO:0033108	mitochondrial respiratory chain complex assembly	3.595167e-3
GO:0006974	response to DNA damage stimulus	3.605464e-3
GO:0030432	peristalsis	3.684535e-3
GO:0051029	rRNA transport	3.762914e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	3.842078e-3
GO:0032392	DNA geometric change	3.872776e-3
GO:0006606	protein import into nucleus	3.972965e-3
GO:0071156	regulation of cell cycle arrest	3.995739e-3
GO:0050689	negative regulation of defense response to virus by host	4.029210e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	4.061351e-3
GO:0070669	response to interleukin-2	4.204157e-3
GO:0071281	cellular response to iron ion	4.204157e-3
GO:2001038	regulation of cellular response to drug	4.204157e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	4.204157e-3
GO:2000685	positive regulation of cellular response to X-ray	4.204157e-3
GO:0035978	histone H2A-S139 phosphorylation	4.204157e-3
GO:0001306	age-dependent response to oxidative stress	4.204157e-3
GO:0035988	chondrocyte proliferation	4.204157e-3
GO:0003131	mesodermal-endodermal cell signaling	4.204157e-3
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	4.204157e-3
GO:0031052	chromosome breakage	4.204157e-3
GO:0051795	positive regulation of catagen	4.298002e-3
GO:0061162	establishment of monopolar cell polarity	4.314086e-3
GO:0003062	regulation of heart rate by chemical signal	4.439223e-3
GO:0007049	cell cycle	4.444906e-3
GO:0072331	signal transduction by p53 class mediator	4.532978e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	4.565721e-3
GO:0015696	ammonium transport	4.586638e-3
GO:2000772	regulation of cellular senescence	4.595275e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	4.693873e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	4.693873e-3
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	4.776268e-3
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	4.776268e-3
GO:0061307	cardiac neural crest cell differentiation involved in heart development	4.872126e-3
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	4.875425e-3
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	4.875425e-3
GO:0060084	synaptic transmission involved in micturition	4.981261e-3
GO:0034259	negative regulation of Rho GTPase activity	4.981261e-3
GO:0010918	positive regulation of mitochondrial membrane potential	4.981261e-3
GO:0045994	positive regulation of translational initiation by iron	4.987741e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	4.987741e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	4.987741e-3
GO:0018242	protein O-linked glycosylation via serine	4.987741e-3
GO:0030221	basophil differentiation	4.987741e-3
GO:0002037	negative regulation of L-glutamate transport	4.987741e-3
GO:0018243	protein O-linked glycosylation via threonine	4.987741e-3
GO:0002385	mucosal immune response	4.999065e-3
GO:0017148	negative regulation of translation	5.098478e-3
GO:0060363	cranial suture morphogenesis	5.192309e-3
GO:0035404	histone-serine phosphorylation	5.198387e-3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	5.249160e-3
GO:0045136	development of secondary sexual characteristics	5.262063e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	5.311542e-3
GO:0018916	nitrobenzene metabolic process	5.311542e-3
GO:0071352	cellular response to interleukin-2	5.311542e-3
GO:0006497	protein lipidation	5.331264e-3
GO:0032367	intracellular cholesterol transport	5.332065e-3
GO:0033002	muscle cell proliferation	5.375519e-3
GO:0048818	positive regulation of hair follicle maturation	5.406037e-3
GO:0002149	hypochlorous acid biosynthetic process	5.406037e-3
GO:0060123	regulation of growth hormone secretion	5.424222e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	5.486407e-3
GO:0072268	pattern specification involved in metanephros development	5.486407e-3
GO:0051170	nuclear import	5.553844e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	5.581501e-3
GO:0072178	nephric duct morphogenesis	5.658985e-3
GO:0000724	double-strand break repair via homologous recombination	5.713901e-3
GO:0002328	pro-B cell differentiation	5.756009e-3
GO:0046543	development of secondary female sexual characteristics	5.917542e-3
GO:0048240	sperm capacitation	5.983617e-3
GO:0006984	ER-nucleus signaling pathway	6.075974e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	6.093999e-3
GO:0034227	tRNA thio-modification	6.093999e-3
GO:0016358	dendrite development	6.165911e-3
GO:0072088	nephron epithelium morphogenesis	6.169818e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	6.197023e-3
GO:0034384	high-density lipoprotein particle clearance	6.206206e-3
GO:0051135	positive regulation of NK T cell activation	6.265471e-3
GO:0051321	meiotic cell cycle	6.276243e-3
GO:0006475	internal protein amino acid acetylation	6.371092e-3
GO:0007080	mitotic metaphase plate congression	6.398421e-3
GO:0021675	nerve development	6.402640e-3
GO:0043526	neuroprotection	6.410156e-3
GO:0009410	response to xenobiotic stimulus	6.456372e-3
GO:0010822	positive regulation of mitochondrion organization	6.552164e-3
GO:0032057	negative regulation of translational initiation in response to stress	6.564815e-3
GO:0008611	ether lipid biosynthetic process	6.564815e-3
GO:0031129	inductive cell-cell signaling	6.564815e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	6.644401e-3
GO:0046599	regulation of centriole replication	6.730979e-3
GO:0000052	citrulline metabolic process	6.730979e-3
GO:0006353	transcription termination, DNA-dependent	6.730979e-3
GO:0000075	cell cycle checkpoint	6.863324e-3
GO:0051006	positive regulation of lipoprotein lipase activity	6.955257e-3
GO:0019240	citrulline biosynthetic process	7.038787e-3
GO:0046931	pore complex assembly	7.057752e-3
GO:0000738	DNA catabolic process, exonucleolytic	7.110926e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	7.204984e-3
GO:0021545	cranial nerve development	7.228179e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	7.302274e-3
GO:0000733	DNA strand renaturation	7.360649e-3
GO:0022613	ribonucleoprotein complex biogenesis	7.423814e-3
GO:0001969	regulation of activation of membrane attack complex	7.555866e-3
GO:0010872	regulation of cholesterol esterification	7.648212e-3
GO:2000172	regulation of branching morphogenesis of a nerve	7.783085e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	7.790375e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	7.950339e-3
GO:0035095	behavioral response to nicotine	7.964286e-3
GO:0043461	proton-transporting ATP synthase complex assembly	7.964286e-3
GO:0006139	nucleobase-containing compound metabolic process	7.977825e-3
GO:0042744	hydrogen peroxide catabolic process	7.984220e-3
GO:0002251	organ or tissue specific immune response	8.087414e-3
GO:0070328	triglyceride homeostasis	8.197566e-3
GO:0007262	STAT protein import into nucleus	8.293542e-3
GO:0030301	cholesterol transport	8.400576e-3
GO:0007076	mitotic chromosome condensation	8.552008e-3
GO:0045069	regulation of viral genome replication	8.617160e-3
GO:0070997	neuron death	8.619886e-3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	8.835802e-3
GO:2000384	negative regulation of ectoderm development	8.866289e-3
GO:0006268	DNA unwinding involved in replication	8.918346e-3
GO:0046015	regulation of transcription by glucose	8.927418e-3
GO:0090185	negative regulation of kidney development	8.959055e-3
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	9.021747e-3
GO:0044260	cellular macromolecule metabolic process	9.065203e-3
GO:0051881	regulation of mitochondrial membrane potential	9.065946e-3
GO:0016573	histone acetylation	9.179602e-3
GO:0051402	neuron apoptosis	9.238638e-3
GO:0010984	regulation of lipoprotein particle clearance	9.287537e-3
GO:0006658	phosphatidylserine metabolic process	9.532512e-3
GO:0031065	positive regulation of histone deacetylation	9.627840e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	9.666476e-3
GO:0000725	recombinational repair	9.743374e-3
GO:0008542	visual learning	9.748748e-3
GO:0072177	mesonephric duct development	9.825198e-3
GO:0008306	associative learning	9.842069e-3
GO:0042982	amyloid precursor protein metabolic process	9.994157e-3
GO:0070831	basement membrane assembly	1.008397e-2
GO:0038027	apolipoprotein A-I-mediated signaling pathway	1.008397e-2
GO:0008636	activation of caspase activity by protein phosphorylation	1.008397e-2
GO:0035409	histone H3-Y41 phosphorylation	1.008397e-2
GO:0072205	metanephric collecting duct development	1.008704e-2
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.009589e-2
GO:0010939	regulation of necrotic cell death	1.011086e-2
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.014416e-2
GO:0048148	behavioral response to cocaine	1.014416e-2
GO:0051382	kinetochore assembly	1.018340e-2
GO:0071460	cellular response to cell-matrix adhesion	1.018340e-2
GO:0045329	carnitine biosynthetic process	1.018340e-2
GO:0003409	optic cup structural organization	1.024631e-2
GO:0021623	oculomotor nerve formation	1.024631e-2
GO:0003404	optic vesicle morphogenesis	1.024631e-2
GO:0006446	regulation of translational initiation	1.024924e-2
GO:0006818	hydrogen transport	1.028113e-2
GO:0071044	histone mRNA catabolic process	1.030667e-2
GO:0007260	tyrosine phosphorylation of STAT protein	1.055363e-2
GO:0006493	protein O-linked glycosylation	1.060249e-2
GO:0072176	nephric duct development	1.072677e-2
GO:0018205	peptidyl-lysine modification	1.091345e-2
GO:0015969	guanosine tetraphosphate metabolic process	1.096299e-2
GO:0007285	primary spermatocyte growth	1.096299e-2
GO:0006256	UDP catabolic process	1.096299e-2
GO:0060125	negative regulation of growth hormone secretion	1.107202e-2
GO:0071217	cellular response to external biotic stimulus	1.107202e-2
GO:0061015	snRNA import into nucleus	1.107202e-2
GO:0051463	negative regulation of cortisol secretion	1.107202e-2
GO:0007057	spindle assembly involved in female meiosis I	1.107202e-2
GO:0021771	lateral geniculate nucleus development	1.107202e-2
GO:0035502	metanephric ureteric bud development	1.107202e-2
GO:0006702	androgen biosynthetic process	1.121918e-2
GO:0045738	negative regulation of DNA repair	1.123253e-2
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.123253e-2
GO:0060018	astrocyte fate commitment	1.129681e-2
GO:0015986	ATP synthesis coupled proton transport	1.131394e-2
GO:0019048	virus-host interaction	1.149740e-2
GO:0018198	peptidyl-cysteine modification	1.165059e-2
GO:0060555	induction of necroptosis by extracellular signals	1.189282e-2
GO:0061312	BMP signaling pathway involved in heart development	1.189282e-2
GO:0045654	positive regulation of megakaryocyte differentiation	1.189282e-2
GO:0032497	detection of lipopolysaccharide	1.189282e-2
GO:0048630	skeletal muscle tissue growth	1.196593e-2
GO:0072593	reactive oxygen species metabolic process	1.205438e-2
GO:0006364	rRNA processing	1.216031e-2
GO:0044065	regulation of respiratory system process	1.218701e-2
GO:0008635	activation of caspase activity by cytochrome c	1.236650e-2
GO:0007064	mitotic sister chromatid cohesion	1.245653e-2
GO:0031440	regulation of mRNA 3'-end processing	1.245653e-2
GO:0060218	hemopoietic stem cell differentiation	1.248280e-2
GO:0045869	negative regulation of retroviral genome replication	1.251287e-2
GO:0034088	maintenance of mitotic sister chromatid cohesion	1.251287e-2
GO:0090342	regulation of cell aging	1.284811e-2
GO:0009437	carnitine metabolic process	1.293894e-2
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	1.295811e-2
GO:0032202	telomere assembly	1.295811e-2
GO:0003130	BMP signaling pathway involved in heart induction	1.295811e-2
GO:0032981	mitochondrial respiratory chain complex I assembly	1.340050e-2
GO:0031442	positive regulation of mRNA 3'-end processing	1.340050e-2
GO:0007618	mating	1.346356e-2
GO:0043484	regulation of RNA splicing	1.365835e-2
GO:0008629	induction of apoptosis by intracellular signals	1.373298e-2
GO:0060670	branching involved in embryonic placenta morphogenesis	1.390493e-2
GO:0007091	mitotic metaphase/anaphase transition	1.392116e-2
GO:0001672	regulation of chromatin assembly or disassembly	1.392116e-2
GO:0019098	reproductive behavior	1.398604e-2
GO:0042758	long-chain fatty acid catabolic process	1.412473e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	1.412473e-2
GO:0042413	carnitine catabolic process	1.412473e-2
GO:0010501	RNA secondary structure unwinding	1.412473e-2
GO:0006498	N-terminal protein lipidation	1.412473e-2
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.416471e-2
GO:0031627	telomeric loop formation	1.416579e-2
GO:0000237	leptotene	1.416579e-2
GO:0071577	zinc ion transmembrane transport	1.438948e-2
GO:0035261	external genitalia morphogenesis	1.448753e-2
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.452328e-2
GO:0021557	oculomotor nerve development	1.452328e-2
GO:0071385	cellular response to glucocorticoid stimulus	1.456542e-2
GO:0072210	metanephric nephron development	1.457787e-2
GO:0030837	negative regulation of actin filament polymerization	1.470187e-2
GO:0007096	regulation of exit from mitosis	1.474408e-2
GO:0061046	regulation of branching involved in lung morphogenesis	1.474408e-2
GO:0035912	dorsal aorta morphogenesis	1.475946e-2
GO:0030038	contractile actin filament bundle assembly	1.475946e-2
GO:0009107	lipoate biosynthetic process	1.475946e-2
GO:0008216	spermidine metabolic process	1.475946e-2
GO:2000018	regulation of male gonad development	1.476452e-2
GO:0007220	Notch receptor processing	1.476452e-2
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	1.484063e-2
GO:0051693	actin filament capping	1.488494e-2
GO:0060557	positive regulation of vitamin D biosynthetic process	1.493441e-2
GO:0090304	nucleic acid metabolic process	1.510878e-2
GO:0010498	proteasomal protein catabolic process	1.524709e-2
GO:0072028	nephron morphogenesis	1.550938e-2
GO:0000278	mitotic cell cycle	1.560497e-2
GO:0006417	regulation of translation	1.583420e-2
GO:2000020	positive regulation of male gonad development	1.591276e-2
GO:0035176	social behavior	1.598226e-2
GO:0015992	proton transport	1.606025e-2
GO:0016575	histone deacetylation	1.610681e-2
GO:0017038	protein import	1.623758e-2
GO:0050925	negative regulation of negative chemotaxis	1.625637e-2
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.637305e-2
GO:0050881	musculoskeletal movement	1.640454e-2
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	1.652771e-2
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.654573e-2
GO:0006829	zinc ion transport	1.668240e-2
GO:0032490	detection of molecule of bacterial origin	1.678670e-2
GO:0021554	optic nerve development	1.681218e-2
GO:0033554	cellular response to stress	1.684630e-2
GO:0006473	protein acetylation	1.690717e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.699946e-2
GO:0010724	regulation of definitive erythrocyte differentiation	1.706803e-2
GO:0006284	base-excision repair	1.714449e-2
GO:0071071	regulation of phospholipid biosynthetic process	1.727025e-2
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.733827e-2
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	1.739727e-2
GO:0070584	mitochondrion morphogenesis	1.752574e-2
GO:0007569	cell aging	1.767814e-2
GO:0001662	behavioral fear response	1.776421e-2
GO:0045922	negative regulation of fatty acid metabolic process	1.776960e-2
GO:0030834	regulation of actin filament depolymerization	1.779072e-2
GO:0032375	negative regulation of cholesterol transport	1.794138e-2
GO:0071549	cellular response to dexamethasone stimulus	1.816871e-2
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.823250e-2