Novel motif:75

name:	motif75_AGCCGAGCGCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0051645	Golgi localization	4.602685e-9
GO:0001823	mesonephros development	1.639116e-8
GO:0021546	rhombomere development	2.353106e-8
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.820718e-8
GO:0021903	rostrocaudal neural tube patterning	3.243012e-8
GO:0007020	microtubule nucleation	1.086945e-7
GO:0021569	rhombomere 3 development	1.395500e-7
GO:0051534	negative regulation of NFAT protein import into nucleus	3.078198e-7
GO:0003310	pancreatic A cell differentiation	3.450924e-7
GO:0072176	nephric duct development	4.030694e-7
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	4.272392e-7
GO:0048752	semicircular canal morphogenesis	4.362855e-7
GO:2001037	positive regulation of tongue muscle cell differentiation	4.499304e-7
GO:0097152	mesenchymal cell apoptosis	4.499304e-7
GO:0060982	coronary artery morphogenesis	4.499304e-7
GO:0001830	trophectodermal cell fate commitment	4.499304e-7
GO:0072178	nephric duct morphogenesis	6.136039e-7
GO:0042473	outer ear morphogenesis	8.140596e-7
GO:0016570	histone modification	9.070684e-7
GO:0006353	transcription termination, DNA-dependent	9.908761e-7
GO:0003406	retinal pigment epithelium development	1.758075e-6
GO:0060023	soft palate development	2.376330e-6
GO:0021612	facial nerve structural organization	2.571636e-6
GO:0006473	protein acetylation	4.140526e-6
GO:0048561	establishment of organ orientation	4.581699e-6
GO:0016569	covalent chromatin modification	4.895032e-6
GO:0031468	nuclear envelope reassembly	5.139698e-6
GO:0061360	optic chiasma development	5.668198e-6
GO:2000597	positive regulation of optic nerve formation	5.668198e-6
GO:0021650	vestibulocochlear nerve formation	5.668198e-6
GO:0035799	ureter maturation	5.668198e-6
GO:0021633	optic nerve structural organization	5.668198e-6
GO:0035305	negative regulation of dephosphorylation	6.824366e-6
GO:0048486	parasympathetic nervous system development	8.937406e-6
GO:0043543	protein acylation	8.956224e-6
GO:0035308	negative regulation of protein dephosphorylation	9.392298e-6
GO:0021570	rhombomere 4 development	1.185942e-5
GO:0048702	embryonic neurocranium morphogenesis	1.373187e-5
GO:0021783	preganglionic parasympathetic nervous system development	1.539726e-5
GO:0055026	negative regulation of cardiac muscle tissue development	1.688108e-5
GO:0035304	regulation of protein dephosphorylation	1.750442e-5
GO:0006475	internal protein amino acid acetylation	1.754480e-5
GO:0003329	pancreatic PP cell fate commitment	1.933456e-5
GO:0003326	pancreatic A cell fate commitment	1.933456e-5
GO:0072385	minus-end-directed organelle transport along microtubule	1.978385e-5
GO:0072268	pattern specification involved in metanephros development	2.023748e-5
GO:0035229	positive regulation of glutamate-cysteine ligase activity	2.386346e-5
GO:0061032	visceral serous pericardium development	3.282669e-5
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	3.282669e-5
GO:0060580	ventral spinal cord interneuron fate determination	3.282669e-5
GO:0003327	type B pancreatic cell fate commitment	3.282669e-5
GO:0015809	arginine transport	3.365620e-5
GO:0070934	CRD-mediated mRNA stabilization	5.038852e-5
GO:0048665	neuron fate specification	5.303835e-5
GO:0032581	ER-dependent peroxisome organization	6.057856e-5
GO:0048663	neuron fate commitment	6.283232e-5
GO:0006386	termination of RNA polymerase III transcription	6.936562e-5
GO:0006385	transcription elongation from RNA polymerase III promoter	6.936562e-5
GO:0072162	metanephric mesenchymal cell differentiation	7.938976e-5
GO:0072179	nephric duct formation	8.452981e-5
GO:2000077	negative regulation of type B pancreatic cell development	8.806752e-5
GO:0072393	microtubule anchoring at microtubule organizing center	9.310849e-5
GO:0051488	activation of anaphase-promoting complex activity	1.081098e-4
GO:0007288	sperm axoneme assembly	1.081098e-4
GO:0007090	regulation of S phase of mitotic cell cycle	1.086375e-4
GO:0016577	histone demethylation	1.095022e-4
GO:0006534	cysteine metabolic process	1.140889e-4
GO:0072075	metanephric mesenchyme development	1.146924e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.155427e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.180885e-4
GO:0021561	facial nerve development	1.229319e-4
GO:0030917	midbrain-hindbrain boundary development	1.262747e-4
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.410106e-4
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.410106e-4
GO:0043973	histone H3-K4 acetylation	1.410106e-4
GO:0072125	negative regulation of glomerular mesangial cell proliferation	1.458399e-4
GO:0021568	rhombomere 2 development	1.504335e-4
GO:0031081	nuclear pore distribution	1.571938e-4
GO:0090102	cochlea development	1.618373e-4
GO:0046984	regulation of hemoglobin biosynthetic process	1.633959e-4
GO:0043967	histone H4 acetylation	1.677662e-4
GO:0000414	regulation of histone H3-K36 methylation	1.781127e-4
GO:0009798	axis specification	1.930547e-4
GO:0032417	positive regulation of sodium:hydrogen antiporter activity	2.021701e-4
GO:0061303	cornea development in camera-type eye	2.030524e-4
GO:0033342	negative regulation of collagen binding	2.149490e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	2.154786e-4
GO:0072166	posterior mesonephric tubule development	2.154786e-4
GO:0034198	cellular response to amino acid starvation	2.154786e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	2.197242e-4
GO:0034401	regulation of transcription by chromatin organization	2.320387e-4
GO:0043267	negative regulation of potassium ion transport	2.326739e-4
GO:0071423	malate transmembrane transport	2.327496e-4
GO:0090324	negative regulation of oxidative phosphorylation	2.327496e-4
GO:0010255	glucose mediated signaling pathway	2.327496e-4
GO:0015709	thiosulfate transport	2.327496e-4
GO:0006844	acyl carnitine transport	2.327496e-4
GO:0043048	dolichyl monophosphate biosynthetic process	2.405547e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	2.419640e-4
GO:0042472	inner ear morphogenesis	2.460934e-4
GO:0042696	menarche	2.663484e-4
GO:0014807	regulation of somitogenesis	2.663484e-4
GO:0070874	negative regulation of glycogen metabolic process	2.855429e-4
GO:0021603	cranial nerve formation	2.855429e-4
GO:0031296	B cell costimulation	2.886976e-4
GO:0071539	protein localization to centrosome	2.903762e-4
GO:0021562	vestibulocochlear nerve development	3.089440e-4
GO:0045819	positive regulation of glycogen catabolic process	3.310736e-4
GO:0045750	positive regulation of S phase of mitotic cell cycle	3.344363e-4
GO:0006482	protein demethylation	3.445557e-4
GO:0021877	forebrain neuron fate commitment	3.572053e-4
GO:0072177	mesonephric duct development	3.573338e-4
GO:0018393	internal peptidyl-lysine acetylation	3.771433e-4
GO:0018394	peptidyl-lysine acetylation	3.771638e-4
GO:0022027	interkinetic nuclear migration	3.777796e-4
GO:0072134	nephrogenic mesenchyme morphogenesis	3.829876e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	3.865822e-4
GO:0045007	depurination	4.123697e-4
GO:0021610	facial nerve morphogenesis	4.174658e-4
GO:0060872	semicircular canal development	4.285099e-4
GO:0048013	ephrin receptor signaling pathway	4.490423e-4
GO:0015680	intracellular copper ion transport	4.572779e-4
GO:0015789	UDP-N-acetylgalactosamine transport	4.572779e-4
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	4.572779e-4
GO:0015787	UDP-glucuronic acid transport	4.572779e-4
GO:0048548	regulation of pinocytosis	4.616057e-4
GO:0019367	fatty acid elongation, saturated fatty acid	4.651143e-4
GO:0046796	viral genome transport in host cell	4.727903e-4
GO:0021796	cerebral cortex regionalization	4.727903e-4
GO:0032864	activation of Cdc42 GTPase activity	4.777151e-4
GO:0060689	cell differentiation involved in salivary gland development	4.778615e-4
GO:0007549	dosage compensation	4.937502e-4
GO:0006285	base-excision repair, AP site formation	4.937502e-4
GO:0035306	positive regulation of dephosphorylation	5.302308e-4
GO:0048255	mRNA stabilization	5.428145e-4
GO:0016573	histone acetylation	5.447362e-4
GO:0071279	cellular response to cobalt ion	5.537527e-4
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	5.537527e-4
GO:0010637	negative regulation of mitochondrial fusion	5.537527e-4
GO:0031119	tRNA pseudouridine synthesis	5.537527e-4
GO:0048102	autophagic cell death	5.708561e-4
GO:0010458	exit from mitosis	5.708561e-4
GO:0035329	hippo signaling cascade	5.833665e-4
GO:0006298	mismatch repair	5.833665e-4
GO:0008272	sulfate transport	5.930176e-4
GO:0043923	positive regulation by host of viral transcription	5.947374e-4
GO:0090241	negative regulation of histone H4 acetylation	5.951428e-4
GO:0043966	histone H3 acetylation	6.014315e-4
GO:0009952	anterior/posterior pattern specification	6.135733e-4
GO:0032312	regulation of ARF GTPase activity	6.185210e-4
GO:0021523	somatic motor neuron differentiation	6.590308e-4
GO:0072300	positive regulation of metanephric glomerulus development	6.616176e-4
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	6.766784e-4
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	6.766784e-4
GO:0032738	positive regulation of interleukin-15 production	6.766784e-4
GO:0021759	globus pallidus development	6.806772e-4
GO:0071110	histone biotinylation	7.011185e-4
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	7.011185e-4
GO:0021528	commissural neuron differentiation in spinal cord	7.011185e-4
GO:0048210	Golgi vesicle fusion to target membrane	7.028390e-4
GO:0035307	positive regulation of protein dephosphorylation	7.088445e-4
GO:0015879	carnitine transport	7.088445e-4
GO:0010225	response to UV-C	7.523892e-4
GO:0008298	intracellular mRNA localization	7.586955e-4
GO:0070988	demethylation	8.570633e-4
GO:0009301	snRNA transcription	8.661029e-4
GO:0070179	D-serine biosynthetic process	8.812619e-4
GO:0051793	medium-chain fatty acid catabolic process	8.812619e-4
GO:0033260	DNA replication involved in S phase	8.812619e-4
GO:0042946	glucoside transport	8.812619e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	8.886503e-4
GO:0003002	regionalization	9.045391e-4
GO:0035566	regulation of metanephros size	9.167107e-4
GO:0045719	negative regulation of glycogen biosynthetic process	9.348095e-4
GO:0034447	very-low-density lipoprotein particle clearance	9.395123e-4
GO:0072133	metanephric mesenchyme morphogenesis	9.473783e-4
GO:0022007	convergent extension involved in neural plate elongation	9.492539e-4
GO:0060923	cardiac muscle cell fate commitment	9.700227e-4
GO:0021986	habenula development	1.049696e-3
GO:0035567	non-canonical Wnt receptor signaling pathway	1.127158e-3
GO:0007614	short-term memory	1.140366e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.230020e-3
GO:0060061	Spemann organizer formation	1.250597e-3
GO:0060177	regulation of angiotensin metabolic process	1.278640e-3
GO:0008033	tRNA processing	1.286206e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	1.293530e-3
GO:0021571	rhombomere 5 development	1.293530e-3
GO:0006853	carnitine shuttle	1.317809e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	1.320800e-3
GO:0021905	forebrain-midbrain boundary formation	1.320800e-3
GO:0003322	pancreatic A cell development	1.320800e-3
GO:0006419	alanyl-tRNA aminoacylation	1.320800e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.320800e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.355002e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.361500e-3
GO:0021895	cerebral cortex neuron differentiation	1.367142e-3
GO:0005981	regulation of glycogen catabolic process	1.391301e-3
GO:0021520	spinal cord motor neuron cell fate specification	1.393120e-3
GO:0016925	protein sumoylation	1.448092e-3
GO:0015802	basic amino acid transport	1.454707e-3
GO:0035284	brain segmentation	1.458687e-3
GO:0071422	succinate transmembrane transport	1.461060e-3
GO:0070194	synaptonemal complex disassembly	1.461060e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.461060e-3
GO:0045908	negative regulation of vasodilation	1.461060e-3
GO:0046015	regulation of transcription by glucose	1.465977e-3
GO:0006363	termination of RNA polymerase I transcription	1.508304e-3
GO:0060430	lung saccule development	1.524825e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	1.524825e-3
GO:0042421	norepinephrine biosynthetic process	1.585415e-3
GO:0021604	cranial nerve structural organization	1.661928e-3
GO:0010994	free ubiquitin chain polymerization	1.662862e-3
GO:0006420	arginyl-tRNA aminoacylation	1.662862e-3
GO:0046950	cellular ketone body metabolic process	1.667453e-3
GO:0000088	mitotic prophase	1.673458e-3
GO:0022601	menstrual cycle phase	1.760897e-3
GO:0042255	ribosome assembly	1.760897e-3
GO:0090103	cochlea morphogenesis	1.766669e-3
GO:0006083	acetate metabolic process	1.809183e-3
GO:0072086	specification of loop of Henle identity	1.837076e-3
GO:0060179	male mating behavior	1.906036e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.906036e-3
GO:0060242	contact inhibition	1.943069e-3
GO:0046952	ketone body catabolic process	1.943069e-3
GO:0060253	negative regulation of glial cell proliferation	2.030691e-3
GO:0006438	valyl-tRNA aminoacylation	2.111542e-3
GO:0043983	histone H4-K12 acetylation	2.124332e-3
GO:0002523	leukocyte migration involved in inflammatory response	2.130688e-3
GO:0002002	regulation of angiotensin levels in blood	2.210187e-3
GO:0045200	establishment of neuroblast polarity	2.223200e-3
GO:0002082	regulation of oxidative phosphorylation	2.223200e-3
GO:0030902	hindbrain development	2.317580e-3
GO:0048103	somatic stem cell division	2.366393e-3
GO:0048149	behavioral response to ethanol	2.399357e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.399361e-3
GO:0060033	anatomical structure regression	2.406935e-3
GO:0072081	specification of nephron tubule identity	2.441283e-3
GO:0046940	nucleoside monophosphate phosphorylation	2.441431e-3
GO:0060465	pharynx development	2.441431e-3
GO:0042942	D-serine transport	2.441431e-3
GO:0002897	positive regulation of central B cell tolerance induction	2.441431e-3
GO:0002508	central tolerance induction	2.441431e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	2.587721e-3
GO:0072164	mesonephric tubule development	2.590942e-3
GO:0021930	cerebellar granule cell precursor proliferation	2.622886e-3
GO:0032790	ribosome disassembly	2.755507e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	2.777201e-3
GO:0046684	response to pyrethroid	2.815872e-3
GO:0006430	lysyl-tRNA aminoacylation	2.826799e-3
GO:0021658	rhombomere 3 morphogenesis	2.839998e-3
GO:0021754	facial nucleus development	2.839998e-3
GO:0080164	regulation of nitric oxide metabolic process	2.912872e-3
GO:0022400	regulation of rhodopsin mediated signaling pathway	2.912872e-3
GO:0016058	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	2.912872e-3
GO:0018026	peptidyl-lysine monomethylation	2.993335e-3
GO:0035414	negative regulation of catenin import into nucleus	3.032549e-3
GO:0030488	tRNA methylation	3.057027e-3
GO:0016140	O-glycoside metabolic process	3.057027e-3
GO:0006538	glutamate catabolic process	3.118786e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	3.118786e-3
GO:0042471	ear morphogenesis	3.206370e-3
GO:0019542	propionate biosynthetic process	3.274102e-3
GO:0019413	acetate biosynthetic process	3.274102e-3
GO:0016571	histone methylation	3.277652e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	3.305705e-3
GO:0033326	cerebrospinal fluid secretion	3.305705e-3
GO:0002693	positive regulation of cellular extravasation	3.305705e-3
GO:0043508	negative regulation of JUN kinase activity	3.457941e-3
GO:0031627	telomeric loop formation	3.464985e-3
GO:0031848	protection from non-homologous end joining at telomere	3.583004e-3
GO:0060022	hard palate development	3.588667e-3
GO:0071109	superior temporal gyrus development	3.794076e-3
GO:0001826	inner cell mass cell differentiation	3.794076e-3
GO:0072298	regulation of metanephric glomerulus development	3.799581e-3
GO:0070286	axonemal dynein complex assembly	3.811959e-3
GO:0070947	neutrophil mediated killing of fungus	3.811959e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	3.848612e-3
GO:0072107	positive regulation of ureteric bud formation	3.864507e-3
GO:0035090	maintenance of apical/basal cell polarity	3.923224e-3
GO:0034770	histone H4-K20 methylation	3.991645e-3
GO:0006369	termination of RNA polymerase II transcription	4.035451e-3
GO:0009264	deoxyribonucleotide catabolic process	4.060432e-3
GO:0030433	ER-associated protein catabolic process	4.069258e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	4.072303e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	4.072303e-3
GO:0060112	generation of ovulation cycle rhythm	4.075978e-3
GO:0048549	positive regulation of pinocytosis	4.075978e-3
GO:0017145	stem cell division	4.103128e-3
GO:0060976	coronary vasculature development	4.201962e-3
GO:0072171	mesonephric tubule morphogenesis	4.231028e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	4.353871e-3
GO:0043418	homocysteine catabolic process	4.434306e-3
GO:0019346	transsulfuration	4.434306e-3
GO:0019343	cysteine biosynthetic process via cystathionine	4.434306e-3
GO:0006535	cysteine biosynthetic process from serine	4.434306e-3
GO:0040040	thermosensory behavior	4.576082e-3
GO:0006177	GMP biosynthetic process	4.610772e-3
GO:0010506	regulation of autophagy	4.631517e-3
GO:0021532	neural tube patterning	4.666431e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	4.707188e-3
GO:0033108	mitochondrial respiratory chain complex assembly	4.764380e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	4.872761e-3
GO:0007379	segment specification	4.874791e-3
GO:0060286	flagellar cell motility	4.886844e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	4.955925e-3
GO:0046078	dUMP metabolic process	5.118504e-3
GO:0071335	hair follicle cell proliferation	5.118504e-3
GO:0032290	peripheral nervous system myelin formation	5.118504e-3
GO:0021644	vagus nerve morphogenesis	5.126801e-3
GO:0035511	oxidative DNA demethylation	5.364758e-3
GO:0001560	regulation of cell growth by extracellular stimulus	5.364758e-3
GO:0003180	aortic valve morphogenesis	5.388744e-3
GO:0009637	response to blue light	5.575847e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	5.605911e-3
GO:0006551	leucine metabolic process	5.645861e-3
GO:0000416	positive regulation of histone H3-K36 methylation	5.745870e-3
GO:0019086	late viral mRNA transcription	5.745870e-3
GO:0043088	regulation of Cdc42 GTPase activity	5.770491e-3
GO:0072180	mesonephric duct morphogenesis	5.788127e-3
GO:0018277	protein deamination	5.795740e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	5.883112e-3
GO:0002003	angiotensin maturation	5.883112e-3
GO:0010587	miRNA catabolic process	5.883112e-3
GO:0021798	forebrain dorsal/ventral pattern formation	6.021858e-3
GO:0034214	protein hexamerization	6.030394e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	6.030394e-3
GO:0002011	morphogenesis of an epithelial sheet	6.255066e-3
GO:0048305	immunoglobulin secretion	6.433372e-3
GO:0070781	response to biotin	6.444939e-3
GO:0010633	negative regulation of epithelial cell migration	6.599746e-3
GO:0006474	N-terminal protein amino acid acetylation	6.599746e-3
GO:0043266	regulation of potassium ion transport	6.641734e-3
GO:2000974	negative regulation of pro-B cell differentiation	6.684332e-3
GO:0042538	hyperosmotic salinity response	6.691110e-3
GO:0070407	oxidation-dependent protein catabolic process	6.809700e-3
GO:0072537	fibroblast activation	6.809700e-3
GO:0006272	leading strand elongation	6.809700e-3
GO:0097039	protein linear polyubiquitination	6.818950e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	6.818950e-3
GO:0090239	regulation of histone H4 acetylation	7.000988e-3
GO:0070166	enamel mineralization	7.000988e-3
GO:0018022	peptidyl-lysine methylation	7.143434e-3
GO:0016574	histone ubiquitination	7.156184e-3
GO:0010991	negative regulation of SMAD protein complex assembly	7.209248e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	7.617193e-3
GO:0070574	cadmium ion transmembrane transport	7.617193e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	7.687183e-3
GO:0048532	anatomical structure arrangement	7.690445e-3
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	7.788258e-3
GO:0006398	histone mRNA 3'-end processing	7.788258e-3
GO:0000415	negative regulation of histone H3-K36 methylation	7.788258e-3
GO:0090192	regulation of glomerulus development	7.826474e-3
GO:0060977	coronary vasculature morphogenesis	7.858446e-3
GO:0001880	Mullerian duct regression	7.858446e-3
GO:0048733	sebaceous gland development	7.925274e-3
GO:0061088	regulation of sequestering of zinc ion	7.971227e-3
GO:0060267	positive regulation of respiratory burst	7.971227e-3
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	8.125466e-3
GO:0008355	olfactory learning	8.125466e-3
GO:0042149	cellular response to glucose starvation	8.283201e-3
GO:0065001	specification of axis polarity	8.285629e-3
GO:0003062	regulation of heart rate by chemical signal	8.285629e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	8.333330e-3
GO:0010923	negative regulation of phosphatase activity	8.396946e-3
GO:0046724	oxalic acid secretion	8.424291e-3
GO:0048242	epinephrine secretion	8.424291e-3
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	8.424291e-3
GO:0021993	initiation of neural tube closure	8.437780e-3
GO:0015734	taurine transport	8.515329e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	8.538862e-3
GO:0007089	traversing start control point of mitotic cell cycle	8.559091e-3
GO:0006536	glutamate metabolic process	8.633053e-3
GO:0042415	norepinephrine metabolic process	8.704948e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	9.010039e-3
GO:0021778	oligodendrocyte cell fate specification	9.165939e-3
GO:0048560	establishment of anatomical structure orientation	9.200391e-3
GO:0042450	arginine biosynthetic process via ornithine	9.256201e-3
GO:0042418	epinephrine biosynthetic process	9.256201e-3
GO:0042780	tRNA 3'-end processing	9.256201e-3
GO:0080009	mRNA methylation	9.256201e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	9.256201e-3
GO:0006585	dopamine biosynthetic process from tyrosine	9.256201e-3
GO:0035852	horizontal cell localization	9.256201e-3
GO:0035849	nephric duct elongation	9.256201e-3
GO:0008049	male courtship behavior	9.256201e-3
GO:0035502	metanephric ureteric bud development	9.256201e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	9.256201e-3
GO:0035847	uterine epithelium development	9.256201e-3
GO:0035846	oviduct epithelium development	9.256201e-3
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	9.333541e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	9.338775e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	9.385585e-3
GO:0010477	response to sulfur dioxide	9.385585e-3
GO:0002457	T cell antigen processing and presentation	9.385585e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	9.456789e-3
GO:0003148	outflow tract septum morphogenesis	9.469294e-3
GO:0015864	pyrimidine nucleoside transport	9.531564e-3
GO:0010507	negative regulation of autophagy	9.534503e-3
GO:0042278	purine nucleoside metabolic process	9.662383e-3
GO:0007158	neuron cell-cell adhesion	9.732554e-3
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	9.794198e-3
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	9.794198e-3
GO:2000667	positive regulation of interleukin-13 secretion	9.794198e-3
GO:2000662	regulation of interleukin-5 secretion	9.794198e-3
GO:2000665	regulation of interleukin-13 secretion	9.794198e-3
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	9.794198e-3
GO:2000664	positive regulation of interleukin-5 secretion	9.794198e-3
GO:0006901	vesicle coating	9.978149e-3
GO:2000737	negative regulation of stem cell differentiation	9.984876e-3
GO:0034261	negative regulation of Ras GTPase activity	9.984876e-3
GO:0061101	neuroendocrine cell differentiation	1.012910e-2
GO:0032606	type I interferon production	1.031701e-2
GO:0006287	base-excision repair, gap-filling	1.071387e-2
GO:0060708	spongiotrophoblast differentiation	1.084073e-2
GO:0048483	autonomic nervous system development	1.100304e-2
GO:0034766	negative regulation of ion transmembrane transport	1.102038e-2
GO:0061144	alveolar secondary septum development	1.102038e-2
GO:0031365	N-terminal protein amino acid modification	1.113353e-2
GO:0016241	regulation of macroautophagy	1.126485e-2
GO:0006244	pyrimidine nucleotide catabolic process	1.135213e-2
GO:0016233	telomere capping	1.144873e-2
GO:0060816	random inactivation of X chromosome	1.185765e-2
GO:0046670	positive regulation of retinal cell programmed cell death	1.185765e-2
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.185765e-2
GO:0048562	embryonic organ morphogenesis	1.211207e-2
GO:0035873	lactate transmembrane transport	1.213428e-2
GO:0048050	post-embryonic eye morphogenesis	1.235194e-2
GO:0035721	intraflagellar retrograde transport	1.235194e-2
GO:0042474	middle ear morphogenesis	1.238458e-2
GO:0031643	positive regulation of myelination	1.241160e-2
GO:0060017	parathyroid gland development	1.242826e-2
GO:0002636	positive regulation of germinal center formation	1.252659e-2
GO:0090104	pancreatic E cell differentiation	1.253871e-2
GO:0034509	centromeric core chromatin assembly	1.253871e-2
GO:0003311	pancreatic D cell differentiation	1.253871e-2
GO:0030393	fructoselysine metabolic process	1.253871e-2
GO:0034260	negative regulation of GTPase activity	1.289292e-2
GO:0017187	peptidyl-glutamic acid carboxylation	1.289292e-2
GO:0019087	transformation of host cell by virus	1.339414e-2
GO:0048268	clathrin coat assembly	1.359564e-2
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.368945e-2
GO:0021588	cerebellum formation	1.368945e-2
GO:2000002	negative regulation of DNA damage checkpoint	1.368945e-2
GO:0021551	central nervous system morphogenesis	1.368945e-2
GO:0002175	protein localization to paranode region of axon	1.368945e-2
GO:0010452	histone H3-K36 methylation	1.369485e-2
GO:0050434	positive regulation of viral transcription	1.379173e-2
GO:0001522	pseudouridine synthesis	1.414104e-2
GO:0030422	production of siRNA involved in RNA interference	1.421707e-2
GO:0031122	cytoplasmic microtubule organization	1.425602e-2
GO:0016576	histone dephosphorylation	1.458953e-2
GO:0000578	embryonic axis specification	1.466089e-2
GO:0014707	branchiomeric skeletal muscle development	1.472895e-2
GO:0051572	negative regulation of histone H3-K4 methylation	1.481505e-2
GO:0018342	protein prenylation	1.481505e-2
GO:0035095	behavioral response to nicotine	1.500314e-2
GO:0045351	type I interferon biosynthetic process	1.500643e-2
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	1.561231e-2
GO:0002691	regulation of cellular extravasation	1.599374e-2
GO:0034063	stress granule assembly	1.600123e-2
GO:0021779	oligodendrocyte cell fate commitment	1.600123e-2
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.601050e-2
GO:0034969	histone arginine methylation	1.628166e-2
GO:0001839	neural plate morphogenesis	1.628166e-2
GO:0090281	negative regulation of calcium ion import	1.629295e-2
GO:0071584	negative regulation of zinc ion import	1.629295e-2
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	1.629295e-2
GO:0051791	medium-chain fatty acid metabolic process	1.629295e-2
GO:0032108	negative regulation of response to nutrient levels	1.630805e-2
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.643050e-2
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.661843e-2
GO:0007386	compartment pattern specification	1.661843e-2
GO:0060160	negative regulation of dopamine receptor signaling pathway	1.682265e-2
GO:0009162	deoxyribonucleoside monophosphate metabolic process	1.682265e-2
GO:0000115	regulation of transcription involved in S phase of mitotic cell cycle	1.682265e-2
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.682265e-2
GO:0051647	nucleus localization	1.698616e-2
GO:0001842	neural fold formation	1.720683e-2
GO:0033278	cell proliferation in midbrain	1.750323e-2
GO:0015842	synaptic vesicle amine transport	1.750323e-2
GO:0002536	respiratory burst involved in inflammatory response	1.760645e-2
GO:0033861	negative regulation of NAD(P)H oxidase activity	1.760645e-2
GO:0008295	spermidine biosynthetic process	1.760645e-2
GO:0006489	dolichyl diphosphate biosynthetic process	1.760645e-2
GO:0060972	left/right pattern formation	1.785511e-2
GO:0015728	mevalonate transport	1.796155e-2
GO:0071394	cellular response to testosterone stimulus	1.796155e-2
GO:0006313	transposition, DNA-mediated	1.796155e-2
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.802392e-2
GO:0035802	adrenal cortex formation	1.802392e-2
GO:0051660	establishment of centrosome localization	1.806292e-2
GO:0042335	cuticle development	1.806292e-2
GO:0021540	corpus callosum morphogenesis	1.806292e-2
GO:0002438	acute inflammatory response to antigenic stimulus	1.806292e-2
GO:0051318	G1 phase	1.829461e-2
GO:0035137	hindlimb morphogenesis	1.900149e-2
GO:0034968	histone lysine methylation	1.922825e-2
GO:0021575	hindbrain morphogenesis	1.943256e-2
GO:0032933	SREBP-mediated signaling pathway	1.960972e-2
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	1.976543e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0015780	nucleotide-sugar transport	5.798993e-8
GO:0050713	negative regulation of interleukin-1 beta secretion	1.896004e-7
GO:0034498	early endosome to Golgi transport	7.956593e-7
GO:0010987	negative regulation of high-density lipoprotein particle clearance	8.355002e-7
GO:0010897	negative regulation of triglyceride catabolic process	8.355002e-7
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.162262e-6
GO:0003002	regionalization	1.752800e-6
GO:0035520	monoubiquitinated protein deubiquitination	2.609846e-6
GO:0031508	centromeric heterochromatin formation	2.609846e-6
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.853508e-6
GO:0010918	positive regulation of mitochondrial membrane potential	2.853508e-6
GO:0016573	histone acetylation	2.881596e-6
GO:0048665	neuron fate specification	4.140602e-6
GO:0021520	spinal cord motor neuron cell fate specification	4.508648e-6
GO:0001824	blastocyst development	4.746904e-6
GO:0006351	transcription, DNA-dependent	5.996310e-6
GO:0031507	heterochromatin formation	6.104385e-6
GO:2000772	regulation of cellular senescence	6.496056e-6
GO:0032774	RNA biosynthetic process	7.059548e-6
GO:0018394	peptidyl-lysine acetylation	8.264849e-6
GO:0021877	forebrain neuron fate commitment	8.368183e-6
GO:0007389	pattern specification process	8.603278e-6
GO:0045750	positive regulation of S phase of mitotic cell cycle	8.853955e-6
GO:0006657	CDP-choline pathway	8.853955e-6
GO:0010467	gene expression	1.073320e-5
GO:0050711	negative regulation of interleukin-1 secretion	1.225759e-5
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.302332e-5
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.302332e-5
GO:0018205	peptidyl-lysine modification	1.441001e-5
GO:0018393	internal peptidyl-lysine acetylation	1.611569e-5
GO:2000078	positive regulation of type B pancreatic cell development	1.626538e-5
GO:0021903	rostrocaudal neural tube patterning	2.347679e-5
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	2.384980e-5
GO:0060976	coronary vasculature development	2.544594e-5
GO:0043966	histone H3 acetylation	2.773486e-5
GO:0006438	valyl-tRNA aminoacylation	3.624695e-5
GO:0046605	regulation of centrosome cycle	3.710471e-5
GO:0090231	regulation of spindle checkpoint	4.504718e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.740261e-5
GO:0015966	diadenosine tetraphosphate biosynthetic process	4.870786e-5
GO:0006409	tRNA export from nucleus	4.870786e-5
GO:0051005	negative regulation of lipoprotein lipase activity	5.098241e-5
GO:0051572	negative regulation of histone H3-K4 methylation	5.641249e-5
GO:0046477	glycosylceramide catabolic process	6.562762e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	6.562762e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	7.186323e-5
GO:0006473	protein acetylation	7.257234e-5
GO:0034227	tRNA thio-modification	7.896427e-5
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	7.896427e-5
GO:0048261	negative regulation of receptor-mediated endocytosis	8.538763e-5
GO:0060977	coronary vasculature morphogenesis	8.926394e-5
GO:0072172	mesonephric tubule formation	9.319755e-5
GO:0021546	rhombomere development	9.843231e-5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	9.882846e-5
GO:0006475	internal protein amino acid acetylation	1.032092e-4
GO:0001709	cell fate determination	1.260358e-4
GO:0016070	RNA metabolic process	1.305307e-4
GO:0007051	spindle organization	1.463359e-4
GO:0072164	mesonephric tubule development	1.542109e-4
GO:0045922	negative regulation of fatty acid metabolic process	1.617471e-4
GO:0021514	ventral spinal cord interneuron differentiation	1.717627e-4
GO:0016567	protein ubiquitination	1.879412e-4
GO:0071168	protein localization to chromatin	1.940799e-4
GO:0000414	regulation of histone H3-K36 methylation	1.961775e-4
GO:0021528	commissural neuron differentiation in spinal cord	2.012294e-4
GO:0001826	inner cell mass cell differentiation	2.036278e-4
GO:0010312	detoxification of zinc ion	2.095353e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	2.115420e-4
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	2.514076e-4
GO:0030878	thyroid gland development	2.519819e-4
GO:0001825	blastocyst formation	2.545648e-4
GO:0070831	basement membrane assembly	2.569080e-4
GO:2000384	negative regulation of ectoderm development	2.666662e-4
GO:0034382	chylomicron remnant clearance	2.670859e-4
GO:0072075	metanephric mesenchyme development	2.864146e-4
GO:0046931	pore complex assembly	2.871870e-4
GO:0051775	response to redox state	3.271094e-4
GO:0048539	bone marrow development	3.280793e-4
GO:2000774	positive regulation of cellular senescence	3.366356e-4
GO:0090402	oncogene-induced senescence	3.366356e-4
GO:0035986	senescence-associated heterochromatin focus formation	3.366356e-4
GO:0097084	vascular smooth muscle cell development	3.420772e-4
GO:0010985	negative regulation of lipoprotein particle clearance	3.561294e-4
GO:0032312	regulation of ARF GTPase activity	3.611261e-4
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	3.639340e-4
GO:0061034	olfactory bulb mitral cell layer development	3.639340e-4
GO:0046599	regulation of centriole replication	3.943938e-4
GO:0000080	G1 phase of mitotic cell cycle	3.966266e-4
GO:0021568	rhombomere 2 development	4.001904e-4
GO:0021798	forebrain dorsal/ventral pattern formation	4.112661e-4
GO:2000112	regulation of cellular macromolecule biosynthetic process	4.132974e-4
GO:0090224	regulation of spindle organization	4.391924e-4
GO:0032446	protein modification by small protein conjugation	4.516481e-4
GO:0044342	type B pancreatic cell proliferation	4.633807e-4
GO:0016139	glycoside catabolic process	4.633807e-4
GO:0000415	negative regulation of histone H3-K36 methylation	4.633807e-4
GO:0001830	trophectodermal cell fate commitment	4.633807e-4
GO:0019348	dolichol metabolic process	4.658775e-4
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	4.705469e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	4.731263e-4
GO:0007059	chromosome segregation	4.931298e-4
GO:0051169	nuclear transport	5.375640e-4
GO:0006913	nucleocytoplasmic transport	5.708285e-4
GO:0008216	spermidine metabolic process	6.028293e-4
GO:0009817	defense response to fungus, incompatible interaction	6.028293e-4
GO:0021527	spinal cord association neuron differentiation	6.035102e-4
GO:0051252	regulation of RNA metabolic process	6.289835e-4
GO:0006355	regulation of transcription, DNA-dependent	6.327045e-4
GO:0061017	hepatoblast differentiation	6.399159e-4
GO:0060948	cardiac vascular smooth muscle cell development	6.399159e-4
GO:0061009	common bile duct development	6.489522e-4
GO:0061032	visceral serous pericardium development	6.545662e-4
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	6.562361e-4
GO:0090209	negative regulation of triglyceride metabolic process	6.865464e-4
GO:0048663	neuron fate commitment	7.085213e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	7.095547e-4
GO:0032057	negative regulation of translational initiation in response to stress	7.673286e-4
GO:0045626	negative regulation of T-helper 1 cell differentiation	7.673286e-4
GO:0009953	dorsal/ventral pattern formation	7.743602e-4
GO:0072393	microtubule anchoring at microtubule organizing center	7.794901e-4
GO:0010799	regulation of peptidyl-threonine phosphorylation	7.962375e-4
GO:0006656	phosphatidylcholine biosynthetic process	8.142770e-4
GO:0035195	gene silencing by miRNA	8.210568e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	8.313276e-4
GO:0048239	negative regulation of DNA recombination at telomere	8.313276e-4
GO:0051684	maintenance of Golgi location	8.313276e-4
GO:0006430	lysyl-tRNA aminoacylation	8.313276e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	8.313276e-4
GO:0046452	dihydrofolate metabolic process	8.313276e-4
GO:0060214	endocardium formation	8.458778e-4
GO:0060318	definitive erythrocyte differentiation	8.836212e-4
GO:0031055	chromatin remodeling at centromere	8.954513e-4
GO:0048103	somatic stem cell division	9.098995e-4
GO:0060037	pharyngeal system development	9.121128e-4
GO:0045875	negative regulation of sister chromatid cohesion	9.306544e-4
GO:0072171	mesonephric tubule morphogenesis	9.550361e-4
GO:0022007	convergent extension involved in neural plate elongation	9.926449e-4
GO:0002098	tRNA wobble uridine modification	9.926449e-4
GO:0021513	spinal cord dorsal/ventral patterning	1.004377e-3
GO:0043543	protein acylation	1.025606e-3
GO:0042733	embryonic digit morphogenesis	1.068012e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	1.089771e-3
GO:0032853	positive regulation of Ran GTPase activity	1.116359e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.120969e-3
GO:0051225	spindle assembly	1.159041e-3
GO:0032007	negative regulation of TOR signaling cascade	1.163985e-3
GO:2000380	regulation of mesoderm development	1.166253e-3
GO:0042976	activation of Janus kinase activity	1.175079e-3
GO:2000142	regulation of transcription initiation, DNA-dependent	1.218826e-3
GO:0021511	spinal cord patterning	1.218826e-3
GO:0032488	Cdc42 protein signal transduction	1.220765e-3
GO:0060620	regulation of cholesterol import	1.225030e-3
GO:0006346	methylation-dependent chromatin silencing	1.225030e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	1.245400e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.247799e-3
GO:2000383	regulation of ectoderm development	1.254914e-3
GO:0007212	dopamine receptor signaling pathway	1.319201e-3
GO:0060396	growth hormone receptor signaling pathway	1.438244e-3
GO:0006325	chromatin organization	1.480265e-3
GO:0006287	base-excision repair, gap-filling	1.577732e-3
GO:0021521	ventral spinal cord interneuron specification	1.610445e-3
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.668207e-3
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.720933e-3
GO:0046580	negative regulation of Ras protein signal transduction	1.737536e-3
GO:0016226	iron-sulfur cluster assembly	1.779194e-3
GO:0090304	nucleic acid metabolic process	1.835533e-3
GO:0021872	forebrain generation of neurons	1.844697e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.849815e-3
GO:0060850	regulation of transcription involved in cell fate commitment	1.904950e-3
GO:0035066	positive regulation of histone acetylation	1.989301e-3
GO:0071378	cellular response to growth hormone stimulus	2.050990e-3
GO:0060579	ventral spinal cord interneuron fate commitment	2.124510e-3
GO:0050995	negative regulation of lipid catabolic process	2.180635e-3
GO:0009798	axis specification	2.184488e-3
GO:0046323	glucose import	2.202815e-3
GO:0071294	cellular response to zinc ion	2.203082e-3
GO:0070078	histone H3-R2 demethylation	2.227233e-3
GO:0070079	histone H4-R3 demethylation	2.227233e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.227233e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.227233e-3
GO:0070508	cholesterol import	2.266796e-3
GO:2000195	negative regulation of female gonad development	2.272827e-3
GO:0051058	negative regulation of small GTPase mediated signal transduction	2.306334e-3
GO:0060621	negative regulation of cholesterol import	2.318381e-3
GO:0045019	negative regulation of nitric oxide biosynthetic process	2.318381e-3
GO:0021569	rhombomere 3 development	2.318381e-3
GO:0055012	ventricular cardiac muscle cell differentiation	2.353413e-3
GO:0035269	protein O-linked mannosylation	2.393946e-3
GO:0035562	negative regulation of chromatin binding	2.393946e-3
GO:0017145	stem cell division	2.462390e-3
GO:0061088	regulation of sequestering of zinc ion	2.477776e-3
GO:0007497	posterior midgut development	2.477776e-3
GO:0035645	enteric smooth muscle cell differentiation	2.477776e-3
GO:0010984	regulation of lipoprotein particle clearance	2.569283e-3
GO:0010824	regulation of centrosome duplication	2.575436e-3
GO:0016568	chromatin modification	2.697353e-3
GO:0006600	creatine metabolic process	2.702879e-3
GO:0060684	epithelial-mesenchymal cell signaling	2.717741e-3
GO:0032926	negative regulation of activin receptor signaling pathway	2.743823e-3
GO:0031427	response to methotrexate	2.743823e-3
GO:0003148	outflow tract septum morphogenesis	2.753468e-3
GO:0008355	olfactory learning	2.872223e-3
GO:0030902	hindbrain development	2.883581e-3
GO:0060911	cardiac cell fate commitment	2.914861e-3
GO:0009952	anterior/posterior pattern specification	2.922639e-3
GO:0042363	fat-soluble vitamin catabolic process	2.941764e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	3.002713e-3
GO:2001076	positive regulation of metanephric ureteric bud development	3.002713e-3
GO:0070171	negative regulation of tooth mineralization	3.002713e-3
GO:0018242	protein O-linked glycosylation via serine	3.002713e-3
GO:0007356	thorax and anterior abdomen determination	3.002713e-3
GO:0018243	protein O-linked glycosylation via threonine	3.002713e-3
GO:0051145	smooth muscle cell differentiation	3.039330e-3
GO:0016926	protein desumoylation	3.079299e-3
GO:0035886	vascular smooth muscle cell differentiation	3.157299e-3
GO:0090307	spindle assembly involved in mitosis	3.164899e-3
GO:0060192	negative regulation of lipase activity	3.392447e-3
GO:0042941	D-alanine transport	3.434324e-3
GO:0080164	regulation of nitric oxide metabolic process	3.434324e-3
GO:0035502	metanephric ureteric bud development	3.434324e-3
GO:0017187	peptidyl-glutamic acid carboxylation	3.434324e-3
GO:0007518	myoblast cell fate determination	3.434324e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	3.434324e-3
GO:0006683	galactosylceramide catabolic process	3.434324e-3
GO:0001570	vasculogenesis	3.437251e-3
GO:0021532	neural tube patterning	3.449142e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	3.492663e-3
GO:0060431	primary lung bud formation	3.492663e-3
GO:0034645	cellular macromolecule biosynthetic process	3.498567e-3
GO:0035414	negative regulation of catenin import into nucleus	3.506636e-3
GO:0035024	negative regulation of Rho protein signal transduction	3.541530e-3
GO:0046639	negative regulation of alpha-beta T cell differentiation	3.541530e-3
GO:0072355	histone H3-T3 phosphorylation	3.544026e-3
GO:0032782	bile acid secretion	3.544026e-3
GO:0003096	renal sodium ion transport	3.544026e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	3.544026e-3
GO:0018293	protein-FAD linkage	3.544026e-3
GO:0016569	covalent chromatin modification	3.552802e-3
GO:0034653	retinoic acid catabolic process	3.865782e-3
GO:0060913	cardiac cell fate determination	3.865782e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.922208e-3
GO:0010614	negative regulation of cardiac muscle hypertrophy	3.934730e-3
GO:0048227	plasma membrane to endosome transport	3.981819e-3
GO:0046604	positive regulation of mitotic centrosome separation	3.981819e-3
GO:0032532	regulation of microvillus length	3.981819e-3
GO:0051645	Golgi localization	4.003573e-3
GO:0022037	metencephalon development	4.068395e-3
GO:0032691	negative regulation of interleukin-1 beta production	4.085830e-3
GO:0035229	positive regulation of glutamate-cysteine ligase activity	4.223060e-3
GO:0010468	regulation of gene expression	4.230478e-3
GO:0007339	binding of sperm to zona pellucida	4.272255e-3
GO:0072074	kidney mesenchyme development	4.272255e-3
GO:0006599	phosphagen metabolic process	4.293600e-3
GO:0042977	activation of JAK2 kinase activity	4.310340e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	4.310340e-3
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	4.386440e-3
GO:0006403	RNA localization	4.394546e-3
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	4.420762e-3
GO:0032328	alanine transport	4.438046e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	4.438046e-3
GO:0046785	microtubule polymerization	4.438046e-3
GO:0035372	protein localization to microtubule	4.449748e-3
GO:0010633	negative regulation of epithelial cell migration	4.449748e-3
GO:0031129	inductive cell-cell signaling	4.563080e-3
GO:0042473	outer ear morphogenesis	4.574792e-3
GO:0010556	regulation of macromolecule biosynthetic process	4.738557e-3
GO:0035194	posttranscriptional gene silencing by RNA	4.738666e-3
GO:0043060	meiotic metaphase I plate congression	4.935757e-3
GO:0042048	olfactory behavior	4.935757e-3
GO:0060711	labyrinthine layer development	5.243402e-3
GO:0001839	neural plate morphogenesis	5.306767e-3
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	5.322623e-3
GO:0046474	glycerophospholipid biosynthetic process	5.337687e-3
GO:0065001	specification of axis polarity	5.459783e-3
GO:0060236	regulation of mitotic spindle organization	5.459783e-3
GO:0043932	ossification involved in bone remodeling	5.459783e-3
GO:0046984	regulation of hemoglobin biosynthetic process	5.459783e-3
GO:0045623	negative regulation of T-helper cell differentiation	5.570608e-3
GO:0017148	negative regulation of translation	5.747903e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.819612e-3
GO:0071354	cellular response to interleukin-6	5.869246e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	5.892096e-3
GO:0015959	diadenosine polyphosphate metabolic process	5.950092e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	5.950092e-3
GO:0045964	positive regulation of dopamine metabolic process	5.950092e-3
GO:2000194	regulation of female gonad development	6.032331e-3
GO:0000281	cytokinesis after mitosis	6.032331e-3
GO:0048840	otolith development	6.131914e-3
GO:0019049	evasion of host defenses by virus	6.154503e-3
GO:0042661	regulation of mesodermal cell fate specification	6.232022e-3
GO:0033566	gamma-tubulin complex localization	6.248090e-3
GO:0015881	creatine transport	6.248090e-3
GO:0010070	zygote asymmetric cell division	6.248090e-3
GO:0014812	muscle cell migration	6.302947e-3
GO:0016570	histone modification	6.495644e-3
GO:0072079	nephron tubule formation	6.638455e-3
GO:0060019	radial glial cell differentiation	6.783832e-3
GO:0071072	negative regulation of phospholipid biosynthetic process	6.873409e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	6.873409e-3
GO:0007181	transforming growth factor beta receptor complex assembly	6.995844e-3
GO:0007089	traversing start control point of mitotic cell cycle	6.995844e-3
GO:0001823	mesonephros development	7.025091e-3
GO:0021895	cerebral cortex neuron differentiation	7.329167e-3
GO:0014826	vein smooth muscle contraction	7.500777e-3
GO:0000278	mitotic cell cycle	7.546414e-3
GO:0031954	positive regulation of protein autophosphorylation	7.570860e-3
GO:0072181	mesonephric duct formation	7.732901e-3
GO:0033484	nitric oxide homeostasis	7.732901e-3
GO:0016082	synaptic vesicle priming	7.794188e-3
GO:0060968	regulation of gene silencing	7.856831e-3
GO:0061205	paramesonephric duct development	8.062495e-3
GO:0072050	S-shaped body morphogenesis	8.111293e-3
GO:0072049	comma-shaped body morphogenesis	8.111293e-3
GO:0032508	DNA duplex unwinding	8.241447e-3
GO:0060971	embryonic heart tube left/right pattern formation	8.399073e-3
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	8.399073e-3
GO:0001828	inner cell mass cellular morphogenesis	8.399073e-3
GO:0003142	cardiogenic plate morphogenesis	8.399073e-3
GO:0007052	mitotic spindle organization	8.429151e-3
GO:0033979	box H/ACA snoRNA metabolic process	8.450791e-3
GO:0018214	protein carboxylation	8.450791e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	8.473538e-3
GO:0032012	regulation of ARF protein signal transduction	8.556084e-3
GO:0051900	regulation of mitochondrial depolarization	8.689727e-3
GO:0048268	clathrin coat assembly	9.043488e-3
GO:0050658	RNA transport	9.130168e-3
GO:0021953	central nervous system neuron differentiation	9.184992e-3
GO:0033119	negative regulation of RNA splicing	9.308626e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	9.308626e-3
GO:0008361	regulation of cell size	9.363196e-3
GO:0006284	base-excision repair	9.396768e-3
GO:0070647	protein modification by small protein conjugation or removal	9.472271e-3
GO:0060317	cardiac epithelial to mesenchymal transition	9.509357e-3
GO:0035036	sperm-egg recognition	9.680702e-3
GO:0001840	neural plate development	9.702894e-3
GO:0021575	hindbrain morphogenesis	9.755870e-3
GO:0000724	double-strand break repair via homologous recombination	9.809319e-3
GO:0090102	cochlea development	9.857173e-3
GO:0061360	optic chiasma development	9.950756e-3
GO:2000597	positive regulation of optic nerve formation	9.950756e-3
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	9.950756e-3
GO:0021650	vestibulocochlear nerve formation	9.950756e-3
GO:0021633	optic nerve structural organization	9.950756e-3
GO:0035799	ureter maturation	9.950756e-3
GO:0060364	frontal suture morphogenesis	9.970559e-3
GO:0007076	mitotic chromosome condensation	1.000283e-2
GO:0033483	gas homeostasis	1.000283e-2
GO:0072348	sulfur compound transport	1.016277e-2
GO:0007140	male meiosis	1.045266e-2
GO:0007379	segment specification	1.046305e-2
GO:0051351	positive regulation of ligase activity	1.052355e-2
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.060746e-2
GO:0021549	cerebellum development	1.062318e-2
GO:0006595	polyamine metabolic process	1.072822e-2
GO:0070979	protein K11-linked ubiquitination	1.073755e-2
GO:0006901	vesicle coating	1.074445e-2
GO:0061384	heart trabecular morphogenesis	1.096873e-2
GO:0001660	fever generation	1.098898e-2
GO:0021508	floor plate formation	1.098898e-2
GO:0002011	morphogenesis of an epithelial sheet	1.102084e-2
GO:0003348	cardiac endothelial cell differentiation	1.102519e-2
GO:0030201	heparan sulfate proteoglycan metabolic process	1.108099e-2
GO:0060421	positive regulation of heart growth	1.108099e-2
GO:0034241	positive regulation of macrophage fusion	1.114547e-2
GO:0046986	negative regulation of hemoglobin biosynthetic process	1.114547e-2
GO:0032383	regulation of intracellular cholesterol transport	1.114547e-2
GO:0021586	pons maturation	1.114547e-2
GO:0060347	heart trabecula formation	1.114650e-2
GO:0048143	astrocyte activation	1.139993e-2
GO:0072078	nephron tubule morphogenesis	1.144609e-2
GO:0043524	negative regulation of neuron apoptosis	1.148199e-2
GO:0007173	epidermal growth factor receptor signaling pathway	1.151548e-2
GO:0009059	macromolecule biosynthetic process	1.153625e-2
GO:2000035	regulation of stem cell division	1.161979e-2
GO:0031848	protection from non-homologous end joining at telomere	1.161979e-2
GO:0021759	globus pallidus development	1.171062e-2
GO:0021571	rhombomere 5 development	1.171062e-2
GO:0010511	regulation of phosphatidylinositol biosynthetic process	1.171062e-2
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.179135e-2
GO:0061011	hepatic duct development	1.187729e-2
GO:0072385	minus-end-directed organelle transport along microtubule	1.187729e-2
GO:0072284	metanephric S-shaped body morphogenesis	1.192969e-2
GO:0021658	rhombomere 3 morphogenesis	1.192969e-2
GO:0072278	metanephric comma-shaped body morphogenesis	1.192969e-2
GO:0021515	cell differentiation in spinal cord	1.193002e-2
GO:0032392	DNA geometric change	1.198509e-2
GO:0045628	regulation of T-helper 2 cell differentiation	1.198837e-2
GO:0042662	negative regulation of mesodermal cell fate specification	1.202115e-2
GO:0032692	negative regulation of interleukin-1 production	1.228549e-2
GO:0034377	plasma lipoprotein particle assembly	1.249384e-2
GO:0021548	pons development	1.269859e-2
GO:0002719	negative regulation of cytokine production involved in immune response	1.269859e-2
GO:0046847	filopodium assembly	1.272131e-2
GO:0009452	RNA capping	1.307243e-2
GO:0007183	SMAD protein complex assembly	1.310253e-2
GO:0051276	chromosome organization	1.320017e-2
GO:0051171	regulation of nitrogen compound metabolic process	1.351436e-2
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.356290e-2
GO:0006511	ubiquitin-dependent protein catabolic process	1.360286e-2
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.367414e-2
GO:0045351	type I interferon biosynthetic process	1.375103e-2
GO:0014056	regulation of acetylcholine secretion	1.375103e-2
GO:0070165	positive regulation of adiponectin secretion	1.384631e-2
GO:0070535	histone H2A K63-linked ubiquitination	1.384631e-2
GO:0051882	mitochondrial depolarization	1.384631e-2
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	1.384631e-2
GO:0042443	phenylethylamine metabolic process	1.384631e-2
GO:0000966	RNA 5'-end processing	1.384631e-2
GO:0033031	positive regulation of neutrophil apoptosis	1.384631e-2
GO:0071071	regulation of phospholipid biosynthetic process	1.384860e-2
GO:0021879	forebrain neuron differentiation	1.402964e-2
GO:0035849	nephric duct elongation	1.418726e-2
GO:0035847	uterine epithelium development	1.418726e-2
GO:0035852	horizontal cell localization	1.418726e-2
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	1.418726e-2
GO:0035846	oviduct epithelium development	1.418726e-2
GO:0070370	cellular heat acclimation	1.418726e-2
GO:0043048	dolichyl monophosphate biosynthetic process	1.418726e-2
GO:0006348	chromatin silencing at telomere	1.418726e-2
GO:0000962	positive regulation of mitochondrial RNA catabolic process	1.418726e-2
GO:0000958	mitochondrial mRNA catabolic process	1.418726e-2
GO:0000965	mitochondrial RNA 3'-end processing	1.418726e-2
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.418726e-2
GO:0032077	positive regulation of deoxyribonuclease activity	1.418726e-2
GO:0035356	cellular triglyceride homeostasis	1.418726e-2
GO:0001755	neural crest cell migration	1.419477e-2
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1.421405e-2
GO:0031914	negative regulation of synaptic plasticity	1.421405e-2
GO:0060177	regulation of angiotensin metabolic process	1.442034e-2
GO:0035284	brain segmentation	1.442034e-2
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.457525e-2
GO:0015693	magnesium ion transport	1.499714e-2
GO:0014051	gamma-aminobutyric acid secretion	1.499714e-2
GO:0032006	regulation of TOR signaling cascade	1.502949e-2
GO:0060375	regulation of mast cell differentiation	1.506464e-2
GO:0035967	cellular response to topologically incorrect protein	1.532495e-2
GO:0046498	S-adenosylhomocysteine metabolic process	1.538619e-2
GO:0021871	forebrain regionalization	1.552428e-2
GO:0030968	endoplasmic reticulum unfolded protein response	1.556896e-2
GO:0021516	dorsal spinal cord development	1.565544e-2
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	1.566255e-2
GO:0032916	positive regulation of transforming growth factor beta3 production	1.618510e-2
GO:0042696	menarche	1.618510e-2
GO:0039020	pronephric nephron tubule development	1.649190e-2
GO:0035565	regulation of pronephros size	1.649190e-2
GO:0021930	cerebellar granule cell precursor proliferation	1.649190e-2
GO:0032530	regulation of microvillus organization	1.659299e-2
GO:0034508	centromere complex assembly	1.660114e-2
GO:0051055	negative regulation of lipid biosynthetic process	1.677892e-2
GO:2000001	regulation of DNA damage checkpoint	1.681864e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.681864e-2
GO:0097152	mesenchymal cell apoptosis	1.681864e-2
GO:0071104	response to interleukin-9	1.681864e-2
GO:0060658	nipple morphogenesis	1.683210e-2
GO:0033505	floor plate morphogenesis	1.683210e-2
GO:0045162	clustering of voltage-gated sodium channels	1.683285e-2
GO:0021562	vestibulocochlear nerve development	1.683285e-2
GO:0007616	long-term memory	1.709925e-2
GO:0060572	morphogenesis of an epithelial bud	1.719930e-2
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.752443e-2
GO:0021869	forebrain ventricular zone progenitor cell division	1.752683e-2
GO:0097116	gephyrin clustering	1.777409e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.814580e-2
GO:0001832	blastocyst growth	1.838319e-2
GO:0007090	regulation of S phase of mitotic cell cycle	1.843599e-2
GO:0045599	negative regulation of fat cell differentiation	1.843808e-2
GO:0009103	lipopolysaccharide biosynthetic process	1.857740e-2
GO:0042637	catagen	1.857740e-2
GO:0007621	negative regulation of female receptivity	1.857740e-2
GO:0000301	retrograde transport, vesicle recycling within Golgi	1.871161e-2
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	1.881912e-2
GO:0000725	recombinational repair	1.906460e-2
GO:0060485	mesenchyme development	1.916170e-2
GO:0051297	centrosome organization	1.952434e-2
GO:0043380	regulation of memory T cell differentiation	1.957844e-2
GO:0048755	branching morphogenesis of a nerve	1.957844e-2
GO:0021578	hindbrain maturation	1.957844e-2
GO:0014741	negative regulation of muscle hypertrophy	1.959351e-2
GO:0030035	microspike assembly	1.963335e-2
GO:0072177	mesonephric duct development	1.969086e-2
GO:0051569	regulation of histone H3-K4 methylation	1.969086e-2
GO:0001778	plasma membrane repair	1.969086e-2
GO:0045017	glycerolipid biosynthetic process	1.980915e-2
GO:0060216	definitive hemopoiesis	2.042021e-2
GO:0022403	cell cycle phase	2.050663e-2
GO:0019941	modification-dependent protein catabolic process	2.051766e-2
GO:0051573	negative regulation of histone H3-K9 methylation	2.056415e-2
GO:0048496	maintenance of organ identity	2.056415e-2
GO:0060319	primitive erythrocyte differentiation	2.082883e-2
GO:0007094	mitotic cell cycle spindle assembly checkpoint	2.082883e-2
GO:0006999	nuclear pore organization	2.100704e-2
GO:0021799	cerebral cortex radially oriented cell migration	2.110785e-2
GO:0060038	cardiac muscle cell proliferation	2.147318e-2
GO:0033209	tumor necrosis factor-mediated signaling pathway	2.147318e-2
GO:0021796	cerebral cortex regionalization	2.150706e-2
GO:0015747	urate transport	2.150706e-2
GO:0009890	negative regulation of biosynthetic process	2.170158e-2
GO:0043632	modification-dependent macromolecule catabolic process	2.170956e-2
GO:0010667	negative regulation of cardiac muscle cell apoptosis	2.185256e-2
GO:0000082	G1/S transition of mitotic cell cycle	2.211541e-2