Novel motif:82

name:	motif82_TTGAATCGCGG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0060017	parathyroid gland development	1.542714e-11
GO:0010994	free ubiquitin chain polymerization	3.388248e-10
GO:0051181	cofactor transport	4.726511e-10
GO:0060535	trachea cartilage morphogenesis	6.931814e-9
GO:0002765	immune response-inhibiting signal transduction	7.900407e-9
GO:0018345	protein palmitoylation	1.399149e-8
GO:0097039	protein linear polyubiquitination	2.008943e-8
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	2.008943e-8
GO:0060764	cell-cell signaling involved in mammary gland development	6.652102e-8
GO:0060534	trachea cartilage development	7.372597e-8
GO:0007091	mitotic metaphase/anaphase transition	9.731518e-8
GO:0046796	viral genome transport in host cell	2.189335e-7
GO:0016926	protein desumoylation	2.451078e-7
GO:0045200	establishment of neuroblast polarity	2.848541e-7
GO:0007140	male meiosis	3.597732e-7
GO:0060482	lobar bronchus development	3.902634e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	4.523659e-7
GO:0051488	activation of anaphase-promoting complex activity	5.297957e-7
GO:0071934	thiamine transmembrane transport	7.342117e-7
GO:0060574	intestinal epithelial cell maturation	8.502365e-7
GO:0048318	axial mesoderm development	1.062413e-6
GO:0015742	alpha-ketoglutarate transport	1.426012e-6
GO:0010458	exit from mitosis	1.648637e-6
GO:0010477	response to sulfur dioxide	1.688548e-6
GO:0002457	T cell antigen processing and presentation	1.688548e-6
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.808424e-6
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	2.367415e-6
GO:0035284	brain segmentation	2.537538e-6
GO:0015884	folic acid transport	2.580302e-6
GO:0097116	gephyrin clustering	2.738650e-6
GO:0033169	histone H3-K9 demethylation	3.179117e-6
GO:0002769	natural killer cell inhibitory signaling pathway	3.337126e-6
GO:0072089	stem cell proliferation	5.484908e-6
GO:0021615	glossopharyngeal nerve morphogenesis	7.090509e-6
GO:0043048	dolichyl monophosphate biosynthetic process	7.915534e-6
GO:0040030	regulation of molecular function, epigenetic	9.603074e-6
GO:0008611	ether lipid biosynthetic process	9.695721e-6
GO:0065001	specification of axis polarity	9.828770e-6
GO:0019048	virus-host interaction	9.847888e-6
GO:0097118	neuroligin clustering	1.043722e-5
GO:0060580	ventral spinal cord interneuron fate determination	1.226006e-5
GO:0003327	type B pancreatic cell fate commitment	1.226006e-5
GO:0051089	constitutive protein ectodomain proteolysis	1.294142e-5
GO:0048320	axial mesoderm formation	1.392753e-5
GO:0048319	axial mesoderm morphogenesis	1.441675e-5
GO:0006635	fatty acid beta-oxidation	1.454997e-5
GO:0008049	male courtship behavior	1.471010e-5
GO:0007141	male meiosis I	1.478614e-5
GO:0031055	chromatin remodeling at centromere	1.784173e-5
GO:0001923	B-1 B cell differentiation	1.968665e-5
GO:0048663	neuron fate commitment	2.071498e-5
GO:0031497	chromatin assembly	2.375349e-5
GO:0044314	protein K27-linked ubiquitination	2.428573e-5
GO:0015728	mevalonate transport	2.493981e-5
GO:0097119	postsynaptic density protein 95 clustering	2.556970e-5
GO:0097104	postsynaptic membrane assembly	2.556970e-5
GO:0015886	heme transport	2.596653e-5
GO:0042373	vitamin K metabolic process	2.706525e-5
GO:2000467	positive regulation of glycogen (starch) synthase activity	3.211861e-5
GO:0042723	thiamine-containing compound metabolic process	3.565196e-5
GO:2000706	negative regulation of dense core granule biogenesis	3.727278e-5
GO:2000798	negative regulation of amniotic stem cell differentiation	3.727278e-5
GO:0006844	acyl carnitine transport	3.727278e-5
GO:0032784	regulation of transcription elongation, DNA-dependent	4.055120e-5
GO:0046092	deoxycytidine metabolic process	5.526441e-5
GO:0007100	mitotic centrosome separation	5.526441e-5
GO:0034241	positive regulation of macrophage fusion	5.526441e-5
GO:0000087	M phase of mitotic cell cycle	6.151595e-5
GO:0006868	glutamine transport	7.218453e-5
GO:0097152	mesenchymal cell apoptosis	7.388022e-5
GO:2001037	positive regulation of tongue muscle cell differentiation	7.388022e-5
GO:0060982	coronary artery morphogenesis	7.388022e-5
GO:0002158	osteoclast proliferation	7.615423e-5
GO:0000279	M phase	7.763569e-5
GO:0071168	protein localization to chromatin	8.364640e-5
GO:0021797	forebrain anterior/posterior pattern specification	8.737062e-5
GO:0006529	asparagine biosynthetic process	9.178289e-5
GO:0048664	neuron fate determination	9.541747e-5
GO:0042074	cell migration involved in gastrulation	1.010130e-4
GO:0035854	eosinophil fate commitment	1.023318e-4
GO:0030222	eosinophil differentiation	1.023318e-4
GO:0006349	regulation of gene expression by genetic imprinting	1.026674e-4
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.077654e-4
GO:2000774	positive regulation of cellular senescence	1.111499e-4
GO:0035986	senescence-associated heterochromatin focus formation	1.111499e-4
GO:0016048	detection of temperature stimulus	1.205899e-4
GO:0048073	regulation of eye pigmentation	1.321243e-4
GO:0030573	bile acid catabolic process	1.328350e-4
GO:0060872	semicircular canal development	1.392553e-4
GO:0046491	L-methylmalonyl-CoA metabolic process	1.451834e-4
GO:0046128	purine ribonucleoside metabolic process	1.480207e-4
GO:0002115	store-operated calcium entry	1.494046e-4
GO:0002069	columnar/cuboidal epithelial cell maturation	1.494046e-4
GO:0006742	NADP catabolic process	1.514692e-4
GO:0007067	mitosis	1.522912e-4
GO:2000465	regulation of glycogen (starch) synthase activity	1.593587e-4
GO:0030262	apoptotic nuclear change	1.608962e-4
GO:0021514	ventral spinal cord interneuron differentiation	1.611385e-4
GO:0009116	nucleoside metabolic process	1.672056e-4
GO:0021871	forebrain regionalization	1.689522e-4
GO:0002003	angiotensin maturation	1.752598e-4
GO:0018872	arsonoacetate metabolic process	1.759616e-4
GO:0007051	spindle organization	1.801294e-4
GO:0000415	negative regulation of histone H3-K36 methylation	1.826249e-4
GO:0031060	regulation of histone methylation	1.973887e-4
GO:0051028	mRNA transport	1.977231e-4
GO:0048075	positive regulation of eye pigmentation	2.131584e-4
GO:0006489	dolichyl diphosphate biosynthetic process	2.204815e-4
GO:0070979	protein K11-linked ubiquitination	2.214140e-4
GO:0071514	genetic imprinting	2.223826e-4
GO:0006333	chromatin assembly or disassembly	2.346049e-4
GO:0006284	base-excision repair	2.359872e-4
GO:0007020	microtubule nucleation	2.623625e-4
GO:0072061	inner medullary collecting duct development	2.675262e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	2.675262e-4
GO:0072060	outer medullary collecting duct development	2.675262e-4
GO:0045647	negative regulation of erythrocyte differentiation	2.682968e-4
GO:0070562	regulation of vitamin D receptor signaling pathway	2.746528e-4
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	2.746528e-4
GO:0070861	regulation of protein exit from endoplasmic reticulum	2.912019e-4
GO:0035461	vitamin transmembrane transport	2.963215e-4
GO:0060452	positive regulation of cardiac muscle contraction	3.151861e-4
GO:0043922	negative regulation by host of viral transcription	3.234570e-4
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	3.523702e-4
GO:0048703	embryonic viscerocranium morphogenesis	3.629527e-4
GO:0060480	lung goblet cell differentiation	3.784685e-4
GO:0051856	adhesion to symbiont	3.790232e-4
GO:0090031	positive regulation of steroid hormone biosynthetic process	3.820711e-4
GO:0042278	purine nucleoside metabolic process	3.875584e-4
GO:0070179	D-serine biosynthetic process	3.909635e-4
GO:0009163	nucleoside biosynthetic process	4.087125e-4
GO:0070345	negative regulation of fat cell proliferation	4.087287e-4
GO:0030574	collagen catabolic process	4.135083e-4
GO:0048285	organelle fission	4.148981e-4
GO:0048538	thymus development	4.250213e-4
GO:0070166	enamel mineralization	4.275620e-4
GO:0007339	binding of sperm to zona pellucida	4.493332e-4
GO:0032446	protein modification by small protein conjugation	4.674252e-4
GO:0018026	peptidyl-lysine monomethylation	4.727307e-4
GO:0032008	positive regulation of TOR signaling cascade	4.995113e-4
GO:0005979	regulation of glycogen biosynthetic process	5.049219e-4
GO:0021986	habenula development	5.083275e-4
GO:0044205	'de novo' UMP biosynthetic process	5.124137e-4
GO:0000414	regulation of histone H3-K36 methylation	5.178217e-4
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	5.281179e-4
GO:0060433	bronchus development	5.653548e-4
GO:0090307	spindle assembly involved in mitosis	5.865579e-4
GO:0070171	negative regulation of tooth mineralization	5.927874e-4
GO:0000236	mitotic prometaphase	5.969886e-4
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	6.642789e-4
GO:0042407	cristae formation	6.642789e-4
GO:0035036	sperm-egg recognition	6.772453e-4
GO:0016567	protein ubiquitination	7.023376e-4
GO:0042117	monocyte activation	7.407522e-4
GO:0048291	isotype switching to IgG isotypes	7.446542e-4
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	7.446542e-4
GO:0002368	B cell cytokine production	7.446542e-4
GO:0033326	cerebrospinal fluid secretion	7.916672e-4
GO:0060285	ciliary cell motility	7.989997e-4
GO:0002002	regulation of angiotensin levels in blood	8.241952e-4
GO:0009234	menaquinone biosynthetic process	8.243564e-4
GO:0021631	optic nerve morphogenesis	8.310941e-4
GO:0032049	cardiolipin biosynthetic process	8.515645e-4
GO:0007079	mitotic chromosome movement towards spindle pole	8.515645e-4
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	8.666904e-4
GO:0046628	positive regulation of insulin receptor signaling pathway	8.692205e-4
GO:0021644	vagus nerve morphogenesis	8.753675e-4
GO:0021658	rhombomere 3 morphogenesis	9.109462e-4
GO:0046607	positive regulation of centrosome cycle	9.823322e-4
GO:0010025	wax biosynthetic process	9.823322e-4
GO:0007224	smoothened signaling pathway	9.834285e-4
GO:0070873	regulation of glycogen metabolic process	1.026952e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	1.076999e-3
GO:0045605	negative regulation of epidermal cell differentiation	1.078382e-3
GO:0043486	histone exchange	1.103026e-3
GO:0030851	granulocyte differentiation	1.128194e-3
GO:0051549	positive regulation of keratinocyte migration	1.134084e-3
GO:0001941	postsynaptic membrane organization	1.154010e-3
GO:0019087	transformation of host cell by virus	1.187320e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.223725e-3
GO:0070647	protein modification by small protein conjugation or removal	1.252747e-3
GO:0032897	negative regulation of viral transcription	1.281006e-3
GO:0043044	ATP-dependent chromatin remodeling	1.310777e-3
GO:0045665	negative regulation of neuron differentiation	1.317386e-3
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.321465e-3
GO:0051301	cell division	1.342576e-3
GO:0034047	regulation of protein phosphatase type 2A activity	1.342578e-3
GO:0051572	negative regulation of histone H3-K4 methylation	1.390947e-3
GO:0048665	neuron fate specification	1.448845e-3
GO:0003329	pancreatic PP cell fate commitment	1.453821e-3
GO:0003326	pancreatic A cell fate commitment	1.453821e-3
GO:0009119	ribonucleoside metabolic process	1.456330e-3
GO:0051180	vitamin transport	1.495006e-3
GO:0070194	synaptonemal complex disassembly	1.504146e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.504146e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.504146e-3
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.504146e-3
GO:0021801	cerebral cortex radial glia guided migration	1.534623e-3
GO:0048384	retinoic acid receptor signaling pathway	1.566631e-3
GO:0072207	metanephric epithelium development	1.635026e-3
GO:0006379	mRNA cleavage	1.655161e-3
GO:0060061	Spemann organizer formation	1.666398e-3
GO:0046485	ether lipid metabolic process	1.674279e-3
GO:0071877	regulation of adrenergic receptor signaling pathway	1.678852e-3
GO:0002575	basophil chemotaxis	1.678852e-3
GO:0060319	primitive erythrocyte differentiation	1.678852e-3
GO:0006610	ribosomal protein import into nucleus	1.703545e-3
GO:0031536	positive regulation of exit from mitosis	1.720615e-3
GO:0070076	histone lysine demethylation	1.747319e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.824513e-3
GO:0061099	negative regulation of protein tyrosine kinase activity	1.857115e-3
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	1.928047e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.932468e-3
GO:0030221	basophil differentiation	1.932468e-3
GO:0006450	regulation of translational fidelity	1.937464e-3
GO:0046604	positive regulation of mitotic centrosome separation	2.026727e-3
GO:2000002	negative regulation of DNA damage checkpoint	2.026727e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	2.026727e-3
GO:0021588	cerebellum formation	2.026727e-3
GO:0021551	central nervous system morphogenesis	2.026727e-3
GO:0085020	protein K6-linked ubiquitination	2.038512e-3
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	2.062618e-3
GO:0021602	cranial nerve morphogenesis	2.063324e-3
GO:0022403	cell cycle phase	2.198451e-3
GO:0060439	trachea morphogenesis	2.198988e-3
GO:0034501	protein localization to kinetochore	2.206226e-3
GO:0060435	bronchiole development	2.278390e-3
GO:0032543	mitochondrial translation	2.420762e-3
GO:0019408	dolichol biosynthetic process	2.446951e-3
GO:0006189	'de novo' IMP biosynthetic process	2.446951e-3
GO:0007096	regulation of exit from mitosis	2.472738e-3
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	2.479917e-3
GO:2000534	positive regulation of renal albumin absorption	2.479917e-3
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	2.479917e-3
GO:2000461	negative regulation of eukaryotic cell surface binding	2.479917e-3
GO:0070994	detection of oxidative stress	2.479917e-3
GO:0043174	nucleoside salvage	2.490117e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	2.490117e-3
GO:0016584	nucleosome positioning	2.490191e-3
GO:0046886	positive regulation of hormone biosynthetic process	2.553070e-3
GO:0071167	ribonucleoprotein complex import into nucleus	2.609974e-3
GO:0010878	cholesterol storage	2.609974e-3
GO:0034728	nucleosome organization	2.622081e-3
GO:0046813	virion attachment, binding of host cell surface receptor	2.664122e-3
GO:0010519	negative regulation of phospholipase activity	2.753507e-3
GO:0072205	metanephric collecting duct development	2.869303e-3
GO:0051225	spindle assembly	2.935533e-3
GO:0006493	protein O-linked glycosylation	3.003047e-3
GO:0065004	protein-DNA complex assembly	3.003545e-3
GO:0019395	fatty acid oxidation	3.025610e-3
GO:0090007	regulation of mitotic anaphase	3.034043e-3
GO:0021703	locus ceruleus development	3.034043e-3
GO:0071166	ribonucleoprotein complex localization	3.057858e-3
GO:0071777	positive regulation of cell cycle cytokinesis	3.070600e-3
GO:0031507	heterochromatin formation	3.081653e-3
GO:0006369	termination of RNA polymerase II transcription	3.112101e-3
GO:0021554	optic nerve development	3.130866e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	3.143327e-3
GO:0061188	negative regulation of chromatin silencing at rDNA	3.143327e-3
GO:0006188	IMP biosynthetic process	3.143327e-3
GO:0002121	inter-male aggressive behavior	3.143327e-3
GO:0051781	positive regulation of cell division	3.154939e-3
GO:0034653	retinoic acid catabolic process	3.183324e-3
GO:0060977	coronary vasculature morphogenesis	3.238838e-3
GO:0090402	oncogene-induced senescence	3.427076e-3
GO:0016140	O-glycoside metabolic process	3.436675e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	3.512721e-3
GO:0006528	asparagine metabolic process	3.512721e-3
GO:0042137	sequestering of neurotransmitter	3.568585e-3
GO:0019086	late viral mRNA transcription	3.568585e-3
GO:0010106	cellular response to iron ion starvation	3.598029e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	3.657581e-3
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	3.661718e-3
GO:0019062	virion attachment to host cell surface receptor	3.682743e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	3.761012e-3
GO:0072274	metanephric glomerular basement membrane development	3.761012e-3
GO:0048677	axon extension involved in regeneration	3.761012e-3
GO:0031081	nuclear pore distribution	3.761012e-3
GO:0002721	regulation of B cell cytokine production	3.761012e-3
GO:0032467	positive regulation of cytokinesis	3.820790e-3
GO:0007143	female meiosis	3.848002e-3
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3.904581e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	4.063595e-3
GO:2001038	regulation of cellular response to drug	4.063595e-3
GO:2000685	positive regulation of cellular response to X-ray	4.063595e-3
GO:0035978	histone H2A-S139 phosphorylation	4.063595e-3
GO:0031052	chromosome breakage	4.063595e-3
GO:0003131	mesodermal-endodermal cell signaling	4.063595e-3
GO:0046134	pyrimidine nucleoside biosynthetic process	4.073978e-3
GO:0035518	histone H2A monoubiquitination	4.095467e-3
GO:0072234	metanephric nephron tubule development	4.123787e-3
GO:0015959	diadenosine polyphosphate metabolic process	4.243783e-3
GO:0030643	cellular phosphate ion homeostasis	4.311440e-3
GO:0090346	cellular organofluorine metabolic process	4.336043e-3
GO:0043602	nitrate catabolic process	4.336043e-3
GO:0046210	nitric oxide catabolic process	4.336043e-3
GO:0045617	negative regulation of keratinocyte differentiation	4.432490e-3
GO:0072526	pyridine-containing compound catabolic process	4.435840e-3
GO:0006054	N-acetylneuraminate metabolic process	4.435840e-3
GO:0046112	nucleobase biosynthetic process	4.466043e-3
GO:0048619	embryonic hindgut morphogenesis	4.471309e-3
GO:0006334	nucleosome assembly	4.537089e-3
GO:0060035	notochord cell development	4.611170e-3
GO:0042069	regulation of catecholamine metabolic process	4.657803e-3
GO:0071824	protein-DNA complex subunit organization	4.705576e-3
GO:0034440	lipid oxidation	4.737638e-3
GO:2000251	positive regulation of actin cytoskeleton reorganization	4.894466e-3
GO:0021568	rhombomere 2 development	4.894466e-3
GO:0072329	monocarboxylic acid catabolic process	4.909710e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	4.968661e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.976717e-3
GO:0044341	sodium-dependent phosphate transport	5.014535e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	5.098604e-3
GO:0001975	response to amphetamine	5.142241e-3
GO:0007389	pattern specification process	5.147709e-3
GO:0072170	metanephric tubule development	5.221990e-3
GO:0050655	dermatan sulfate proteoglycan metabolic process	5.226758e-3
GO:0006406	mRNA export from nucleus	5.353488e-3
GO:0030953	astral microtubule organization	5.551747e-3
GO:0033034	positive regulation of myeloid cell apoptosis	5.837105e-3
GO:0021545	cranial nerve development	5.861638e-3
GO:0061090	positive regulation of sequestering of zinc ion	5.967938e-3
GO:0090343	positive regulation of cell aging	6.020166e-3
GO:0090068	positive regulation of cell cycle process	6.283331e-3
GO:0042418	epinephrine biosynthetic process	6.288548e-3
GO:0019358	nicotinate nucleotide salvage	6.288548e-3
GO:0006585	dopamine biosynthetic process from tyrosine	6.288548e-3
GO:0048713	regulation of oligodendrocyte differentiation	6.299893e-3
GO:2000772	regulation of cellular senescence	6.551978e-3
GO:0051302	regulation of cell division	6.660060e-3
GO:0006426	glycyl-tRNA aminoacylation	6.678076e-3
GO:0018022	peptidyl-lysine methylation	6.693025e-3
GO:0021517	ventral spinal cord development	6.754443e-3
GO:0035519	protein K29-linked ubiquitination	6.791145e-3
GO:0045738	negative regulation of DNA repair	6.882456e-3
GO:0060379	cardiac muscle cell myoblast differentiation	7.023525e-3
GO:0002380	immunoglobulin secretion involved in immune response	7.023525e-3
GO:0051701	interaction with host	7.220699e-3
GO:0016925	protein sumoylation	7.345605e-3
GO:0006546	glycine catabolic process	7.438953e-3
GO:0000278	mitotic cell cycle	7.446913e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	7.710937e-3
GO:0090398	cellular senescence	7.722293e-3
GO:0021997	neural plate axis specification	7.930995e-3
GO:0090342	regulation of cell aging	7.935050e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	7.962180e-3
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	7.962180e-3
GO:0090030	regulation of steroid hormone biosynthetic process	7.975005e-3
GO:0021515	cell differentiation in spinal cord	8.096421e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	8.108046e-3
GO:0051569	regulation of histone H3-K4 methylation	8.108046e-3
GO:0021799	cerebral cortex radially oriented cell migration	8.172355e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	8.180938e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	8.180938e-3
GO:0051253	negative regulation of RNA metabolic process	8.375006e-3
GO:2000036	regulation of stem cell maintenance	8.722732e-3
GO:0072054	renal outer medulla development	8.753261e-3
GO:0072053	renal inner medulla development	8.753261e-3
GO:0035988	chondrocyte proliferation	8.925401e-3
GO:0002118	aggressive behavior	8.951384e-3
GO:0000730	DNA recombinase assembly	8.951384e-3
GO:0032465	regulation of cytokinesis	9.033702e-3
GO:0009190	cyclic nucleotide biosynthetic process	9.114812e-3
GO:0009124	nucleoside monophosphate biosynthetic process	9.133377e-3
GO:0030208	dermatan sulfate biosynthetic process	9.344343e-3
GO:0072044	collecting duct development	9.538338e-3
GO:2000736	regulation of stem cell differentiation	9.563046e-3
GO:0045221	negative regulation of FasL biosynthetic process	9.614884e-3
GO:2000655	negative regulation of cellular response to testosterone stimulus	9.614884e-3
GO:0031937	positive regulation of chromatin silencing	9.614884e-3
GO:0006343	establishment of chromatin silencing	9.614884e-3
GO:0002731	negative regulation of dendritic cell cytokine production	9.614884e-3
GO:0060484	lung-associated mesenchyme development	1.000277e-2
GO:2000737	negative regulation of stem cell differentiation	1.005837e-2
GO:0033627	cell adhesion mediated by integrin	1.008130e-2
GO:0045682	regulation of epidermis development	1.009522e-2
GO:0006914	autophagy	1.021365e-2
GO:0006047	UDP-N-acetylglucosamine metabolic process	1.021531e-2
GO:0048144	fibroblast proliferation	1.022287e-2
GO:0007379	segment specification	1.029010e-2
GO:0072202	cell differentiation involved in metanephros development	1.032678e-2
GO:2000272	negative regulation of receptor activity	1.032678e-2
GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	1.034810e-2
GO:0060460	left lung morphogenesis	1.034810e-2
GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	1.034810e-2
GO:0002085	inhibition of neuroepithelial cell differentiation	1.034810e-2
GO:0048327	axial mesodermal cell fate specification	1.034810e-2
GO:0002418	immune response to tumor cell	1.034810e-2
GO:0035522	monoubiquitinated histone H2A deubiquitination	1.034810e-2
GO:0032439	endosome localization	1.036250e-2
GO:0015881	creatine transport	1.036250e-2
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.049979e-2
GO:0043488	regulation of mRNA stability	1.052031e-2
GO:0002693	positive regulation of cellular extravasation	1.052639e-2
GO:0032727	positive regulation of interferon-alpha production	1.053016e-2
GO:0043255	regulation of carbohydrate biosynthetic process	1.066785e-2
GO:0072070	loop of Henle development	1.073064e-2
GO:0000086	G2/M transition of mitotic cell cycle	1.086237e-2
GO:0045793	positive regulation of cell size	1.092792e-2
GO:0006497	protein lipidation	1.099611e-2
GO:0021522	spinal cord motor neuron differentiation	1.105550e-2
GO:0060579	ventral spinal cord interneuron fate commitment	1.107578e-2
GO:0051168	nuclear export	1.136269e-2
GO:0055062	phosphate ion homeostasis	1.143785e-2
GO:0014013	regulation of gliogenesis	1.147885e-2
GO:0000375	RNA splicing, via transesterification reactions	1.172976e-2
GO:0070193	synaptonemal complex organization	1.204330e-2
GO:0007501	mesodermal cell fate specification	1.212870e-2
GO:0010963	regulation of L-arginine import	1.263436e-2
GO:0014028	notochord formation	1.269331e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.277762e-2
GO:0010216	maintenance of DNA methylation	1.277992e-2
GO:0060968	regulation of gene silencing	1.285651e-2
GO:0003002	regionalization	1.287594e-2
GO:0015866	ADP transport	1.315164e-2
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.315164e-2
GO:0021819	layer formation in cerebral cortex	1.318683e-2
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.334273e-2
GO:0043173	nucleotide salvage	1.336892e-2
GO:0048793	pronephros development	1.378105e-2
GO:0051615	histamine uptake	1.378401e-2
GO:0042414	epinephrine metabolic process	1.378401e-2
GO:0051567	histone H3-K9 methylation	1.383667e-2
GO:0051349	positive regulation of lyase activity	1.424979e-2
GO:0009952	anterior/posterior pattern specification	1.439228e-2
GO:2000143	negative regulation of transcription initiation, DNA-dependent	1.464861e-2
GO:0031427	response to methotrexate	1.464861e-2
GO:0003406	retinal pigment epithelium development	1.464861e-2
GO:0006000	fructose metabolic process	1.465174e-2
GO:0031017	exocrine pancreas development	1.466205e-2
GO:0032352	positive regulation of hormone metabolic process	1.474011e-2
GO:0090083	regulation of inclusion body assembly	1.474284e-2
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.481283e-2
GO:0060177	regulation of angiotensin metabolic process	1.481750e-2
GO:0030388	fructose 1,6-bisphosphate metabolic process	1.486527e-2
GO:0030421	defecation	1.502849e-2
GO:0071028	nuclear mRNA surveillance	1.502849e-2
GO:0070669	response to interleukin-2	1.509529e-2
GO:0044243	multicellular organismal catabolic process	1.515401e-2
GO:0071312	cellular response to alkaloid	1.521157e-2
GO:0048702	embryonic neurocranium morphogenesis	1.522864e-2
GO:0018027	peptidyl-lysine dimethylation	1.525078e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	1.525078e-2
GO:0090037	positive regulation of protein kinase C signaling cascade	1.557860e-2
GO:0006002	fructose 6-phosphate metabolic process	1.580805e-2
GO:0043171	peptide catabolic process	1.580805e-2
GO:0090003	regulation of establishment of protein localization in plasma membrane	1.599016e-2
GO:0045892	negative regulation of transcription, DNA-dependent	1.607330e-2
GO:0001919	regulation of receptor recycling	1.622496e-2
GO:0003323	type B pancreatic cell development	1.622496e-2
GO:0048560	establishment of anatomical structure orientation	1.630756e-2
GO:0010085	polarity specification of proximal/distal axis	1.639523e-2
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	1.643767e-2
GO:0001840	neural plate development	1.648202e-2
GO:0060576	intestinal epithelial cell development	1.661161e-2
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.677346e-2
GO:0032418	lysosome localization	1.680357e-2
GO:0030718	germ-line stem cell maintenance	1.680357e-2
GO:0015870	acetylcholine transport	1.680357e-2
GO:0030539	male genitalia development	1.691169e-2
GO:0006421	asparaginyl-tRNA aminoacylation	1.697439e-2
GO:0072078	nephron tubule morphogenesis	1.708886e-2
GO:0046885	regulation of hormone biosynthetic process	1.723666e-2
GO:0030878	thyroid gland development	1.735964e-2
GO:0045685	regulation of glial cell differentiation	1.755925e-2
GO:0016486	peptide hormone processing	1.767698e-2
GO:0048203	vesicle targeting, trans-Golgi to endosome	1.770772e-2
GO:2000597	positive regulation of optic nerve formation	1.770772e-2
GO:0061360	optic chiasma development	1.770772e-2
GO:0034633	retinol transport	1.770772e-2
GO:0021633	optic nerve structural organization	1.770772e-2
GO:0021650	vestibulocochlear nerve formation	1.770772e-2
GO:0035799	ureter maturation	1.770772e-2
GO:0016090	prenol metabolic process	1.794593e-2
GO:0006689	ganglioside catabolic process	1.806015e-2
GO:0048102	autophagic cell death	1.831698e-2
GO:0006772	thiamine metabolic process	1.831698e-2
GO:0051798	positive regulation of hair follicle development	1.835497e-2
GO:0043487	regulation of RNA stability	1.865811e-2
GO:0009229	thiamine diphosphate biosynthetic process	1.882285e-2
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.887259e-2
GO:0043097	pyrimidine nucleoside salvage	1.899278e-2
GO:0070734	histone H3-K27 methylation	1.901257e-2
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	1.916692e-2
GO:0055119	relaxation of cardiac muscle	1.935608e-2
GO:0035112	genitalia morphogenesis	1.942937e-2
GO:0010592	positive regulation of lamellipodium assembly	1.959945e-2
GO:0051702	interaction with symbiont	1.980654e-2
GO:0042796	snRNA transcription from RNA polymerase III promoter	1.990064e-2
GO:0080164	regulation of nitric oxide metabolic process	1.990064e-2
GO:0042795	snRNA transcription from RNA polymerase II promoter	1.990064e-2
GO:0008052	sensory organ boundary specification	1.990064e-2
GO:0007285	primary spermatocyte growth	1.990064e-2
GO:0010266	response to vitamin B1	1.990064e-2
GO:0043467	regulation of generation of precursor metabolites and energy	1.990784e-2
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	2.007074e-2
GO:0034120	positive regulation of erythrocyte aggregation	2.009768e-2
GO:0001808	negative regulation of type IV hypersensitivity	2.009768e-2
GO:0001708	cell fate specification	2.060984e-2
GO:0034770	histone H4-K20 methylation	2.068421e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042053	regulation of dopamine metabolic process	6.506910e-12
GO:0042069	regulation of catecholamine metabolic process	3.672090e-11
GO:0046907	intracellular transport	7.544624e-10
GO:0070727	cellular macromolecule localization	8.551857e-10
GO:0060433	bronchus development	1.044026e-9
GO:0008104	protein localization	1.783958e-9
GO:0006886	intracellular protein transport	2.925748e-9
GO:0034613	cellular protein localization	4.481426e-9
GO:0051169	nuclear transport	1.709092e-8
GO:0034502	protein localization to chromosome	1.832672e-8
GO:0050668	positive regulation of homocysteine metabolic process	2.243027e-8
GO:0045963	negative regulation of dopamine metabolic process	2.243027e-8
GO:0033036	macromolecule localization	3.893024e-8
GO:0060482	lobar bronchus development	4.177954e-8
GO:0045184	establishment of protein localization	4.294485e-8
GO:0021797	forebrain anterior/posterior pattern specification	4.633088e-8
GO:0006913	nucleocytoplasmic transport	6.047643e-8
GO:0033365	protein localization to organelle	2.022698e-7
GO:0043297	apical junction assembly	2.116717e-7
GO:0033240	positive regulation of cellular amine metabolic process	3.489577e-7
GO:0006605	protein targeting	3.657957e-7
GO:0015031	protein transport	4.213379e-7
GO:0070830	tight junction assembly	4.269109e-7
GO:0021871	forebrain regionalization	4.499835e-7
GO:0042424	catecholamine catabolic process	4.618897e-7
GO:0008063	Toll signaling pathway	4.846066e-7
GO:0002541	activation of plasma proteins involved in acute inflammatory response	4.846066e-7
GO:0006493	protein O-linked glycosylation	4.934581e-7
GO:0072355	histone H3-T3 phosphorylation	8.504202e-7
GO:0046038	GMP catabolic process	1.169927e-6
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.169927e-6
GO:0032264	IMP salvage	1.169927e-6
GO:0006178	guanine salvage	1.169927e-6
GO:0022417	protein maturation by protein folding	1.169927e-6
GO:0032263	GMP salvage	1.169927e-6
GO:0060948	cardiac vascular smooth muscle cell development	1.186573e-6
GO:0060439	trachea morphogenesis	1.541621e-6
GO:0000059	protein import into nucleus, docking	2.427392e-6
GO:0007043	cell-cell junction assembly	2.600038e-6
GO:0060534	trachea cartilage development	2.806083e-6
GO:0046604	positive regulation of mitotic centrosome separation	3.378611e-6
GO:0060535	trachea cartilage morphogenesis	3.387810e-6
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	3.665796e-6
GO:0051641	cellular localization	3.947019e-6
GO:0042420	dopamine catabolic process	4.242739e-6
GO:0070935	3'-UTR-mediated mRNA stabilization	4.633136e-6
GO:0016572	histone phosphorylation	5.550130e-6
GO:0033238	regulation of cellular amine metabolic process	7.548330e-6
GO:0090161	Golgi ribbon formation	7.895803e-6
GO:0072061	inner medullary collecting duct development	7.895803e-6
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	7.895803e-6
GO:0072060	outer medullary collecting duct development	7.895803e-6
GO:0031914	negative regulation of synaptic plasticity	8.165069e-6
GO:0009225	nucleotide-sugar metabolic process	8.879479e-6
GO:0072236	metanephric loop of Henle development	9.549396e-6
GO:0060947	cardiac vascular smooth muscle cell differentiation	9.740271e-6
GO:0072070	loop of Henle development	1.011550e-5
GO:0051176	positive regulation of sulfur metabolic process	1.124477e-5
GO:0019348	dolichol metabolic process	1.124477e-5
GO:0071169	establishment of protein localization to chromatin	1.126647e-5
GO:0006611	protein export from nucleus	1.363056e-5
GO:0051030	snRNA transport	1.379969e-5
GO:0045964	positive regulation of dopamine metabolic process	1.379969e-5
GO:0006610	ribosomal protein import into nucleus	1.573376e-5
GO:0006403	RNA localization	1.906965e-5
GO:0035269	protein O-linked mannosylation	2.230337e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.300553e-5
GO:0007064	mitotic sister chromatid cohesion	2.883526e-5
GO:0007049	cell cycle	3.167493e-5
GO:0017038	protein import	3.426748e-5
GO:0018095	protein polyglutamylation	4.065928e-5
GO:0051649	establishment of localization in cell	4.311181e-5
GO:0015870	acetylcholine transport	4.815834e-5
GO:0000086	G2/M transition of mitotic cell cycle	4.910854e-5
GO:0006260	DNA replication	6.650348e-5
GO:0070831	basement membrane assembly	6.771811e-5
GO:0018364	peptidyl-glutamine methylation	6.771811e-5
GO:0006507	GPI anchor release	6.771811e-5
GO:0072205	metanephric collecting duct development	7.536563e-5
GO:0043103	hypoxanthine salvage	7.641656e-5
GO:0032261	purine nucleotide salvage	7.641656e-5
GO:0006168	adenine salvage	7.641656e-5
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	8.304546e-5
GO:0035176	social behavior	8.609402e-5
GO:0051705	behavioral interaction between organisms	8.647667e-5
GO:0010225	response to UV-C	9.842549e-5
GO:0035912	dorsal aorta morphogenesis	1.074201e-4
GO:0006435	threonyl-tRNA aminoacylation	1.074201e-4
GO:0030038	contractile actin filament bundle assembly	1.074201e-4
GO:0009169	purine ribonucleoside monophosphate catabolic process	1.089966e-4
GO:0071168	protein localization to chromatin	1.201756e-4
GO:0046475	glycerophospholipid catabolic process	1.418044e-4
GO:0034441	plasma lipoprotein particle oxidation	1.520195e-4
GO:0031110	regulation of microtubule polymerization or depolymerization	1.565720e-4
GO:0042417	dopamine metabolic process	1.631765e-4
GO:0042335	cuticle development	1.833023e-4
GO:0021846	cell proliferation in forebrain	1.985824e-4
GO:0060574	intestinal epithelial cell maturation	2.043845e-4
GO:0072054	renal outer medulla development	2.214924e-4
GO:0051561	elevation of mitochondrial calcium ion concentration	2.321137e-4
GO:0008298	intracellular mRNA localization	2.406591e-4
GO:0021526	medial motor column neuron differentiation	2.406591e-4
GO:0051604	protein maturation	2.569047e-4
GO:0002042	cell migration involved in sprouting angiogenesis	2.590401e-4
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	2.617763e-4
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	2.734926e-4
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	2.790249e-4
GO:0032494	response to peptidoglycan	3.213077e-4
GO:0043094	cellular metabolic compound salvage	3.326024e-4
GO:0046607	positive regulation of centrosome cycle	3.339410e-4
GO:0046602	regulation of mitotic centrosome separation	3.339410e-4
GO:0060235	lens induction in camera-type eye	3.382861e-4
GO:0003348	cardiac endothelial cell differentiation	4.079550e-4
GO:0072594	establishment of protein localization to organelle	4.146749e-4
GO:0019673	GDP-mannose metabolic process	4.161687e-4
GO:0071780	mitotic cell cycle G2/M transition checkpoint	4.210856e-4
GO:0045647	negative regulation of erythrocyte differentiation	4.454908e-4
GO:0051615	histamine uptake	4.781317e-4
GO:2000384	negative regulation of ectoderm development	4.797221e-4
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	4.797221e-4
GO:0031116	positive regulation of microtubule polymerization	5.025618e-4
GO:0097084	vascular smooth muscle cell development	5.081392e-4
GO:0060764	cell-cell signaling involved in mammary gland development	5.172420e-4
GO:0000238	zygotene	5.172420e-4
GO:0002098	tRNA wobble uridine modification	5.172683e-4
GO:0006606	protein import into nucleus	5.555912e-4
GO:0046330	positive regulation of JNK cascade	5.566118e-4
GO:0018293	protein-FAD linkage	6.053661e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	6.053661e-4
GO:0043173	nucleotide salvage	6.160076e-4
GO:0030521	androgen receptor signaling pathway	6.220124e-4
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	6.373527e-4
GO:0002002	regulation of angiotensin levels in blood	6.373527e-4
GO:0033136	serine phosphorylation of STAT3 protein	6.502953e-4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	6.725728e-4
GO:0061015	snRNA import into nucleus	7.019804e-4
GO:0042941	D-alanine transport	7.019804e-4
GO:0021771	lateral geniculate nucleus development	7.019804e-4
GO:0009443	pyridoxal 5'-phosphate salvage	7.019804e-4
GO:0072053	renal inner medulla development	7.076926e-4
GO:0015697	quaternary ammonium group transport	7.673269e-4
GO:0045738	negative regulation of DNA repair	7.789379e-4
GO:0043096	purine base salvage	7.812850e-4
GO:0007062	sister chromatid cohesion	8.079023e-4
GO:0033057	multicellular organismal reproductive behavior	8.083731e-4
GO:0051646	mitochondrion localization	8.915064e-4
GO:0015872	dopamine transport	9.487579e-4
GO:0034227	tRNA thio-modification	9.796969e-4
GO:2000383	regulation of ectoderm development	9.796969e-4
GO:0006177	GMP biosynthetic process	9.796969e-4
GO:0010045	response to nickel ion	1.040559e-3
GO:0060084	synaptic transmission involved in micturition	1.040559e-3
GO:0006597	spermine biosynthetic process	1.040559e-3
GO:0045216	cell-cell junction organization	1.048366e-3
GO:0051168	nuclear export	1.049996e-3
GO:0061025	membrane fusion	1.060264e-3
GO:0000070	mitotic sister chromatid segregation	1.088067e-3
GO:0010659	cardiac muscle cell apoptosis	1.096756e-3
GO:0045764	positive regulation of cellular amino acid metabolic process	1.115898e-3
GO:0000278	mitotic cell cycle	1.117540e-3
GO:0030382	sperm mitochondrion organization	1.134863e-3
GO:0006685	sphingomyelin catabolic process	1.134863e-3
GO:0032098	regulation of appetite	1.151133e-3
GO:0048488	synaptic vesicle endocytosis	1.161776e-3
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.166531e-3
GO:0021819	layer formation in cerebral cortex	1.166531e-3
GO:0000087	M phase of mitotic cell cycle	1.178193e-3
GO:0051170	nuclear import	1.214434e-3
GO:0070509	calcium ion import	1.247165e-3
GO:0007067	mitosis	1.297201e-3
GO:0006040	amino sugar metabolic process	1.299324e-3
GO:0045933	positive regulation of muscle contraction	1.405807e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.429019e-3
GO:0010735	positive regulation of transcription via serum response element binding	1.462055e-3
GO:0001975	response to amphetamine	1.513926e-3
GO:0060480	lung goblet cell differentiation	1.520922e-3
GO:0060347	heart trabecula formation	1.569060e-3
GO:0034501	protein localization to kinetochore	1.587844e-3
GO:0060438	trachea development	1.611371e-3
GO:0021670	lateral ventricle development	1.636564e-3
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	1.656280e-3
GO:0070507	regulation of microtubule cytoskeleton organization	1.669118e-3
GO:0046833	positive regulation of RNA export from nucleus	1.680426e-3
GO:0006505	GPI anchor metabolic process	1.680923e-3
GO:0090076	relaxation of skeletal muscle	1.686687e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.686687e-3
GO:0031577	spindle checkpoint	1.692556e-3
GO:0022009	central nervous system vasculogenesis	1.692556e-3
GO:2000685	positive regulation of cellular response to X-ray	1.819291e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	1.819291e-3
GO:2001038	regulation of cellular response to drug	1.819291e-3
GO:0035988	chondrocyte proliferation	1.819291e-3
GO:0035978	histone H2A-S139 phosphorylation	1.819291e-3
GO:0003131	mesodermal-endodermal cell signaling	1.819291e-3
GO:0006188	IMP biosynthetic process	1.819291e-3
GO:0031052	chromosome breakage	1.819291e-3
GO:0006888	ER to Golgi vesicle-mediated transport	1.828110e-3
GO:0016188	synaptic vesicle maturation	1.840005e-3
GO:0009083	branched chain family amino acid catabolic process	1.906231e-3
GO:0015874	norepinephrine transport	1.910001e-3
GO:0042402	cellular biogenic amine catabolic process	1.944614e-3
GO:0006338	chromatin remodeling	1.950021e-3
GO:0072044	collecting duct development	2.152197e-3
GO:0019835	cytolysis	2.222705e-3
GO:0060177	regulation of angiotensin metabolic process	2.243362e-3
GO:0033561	regulation of water loss via skin	2.326237e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	2.326237e-3
GO:0035886	vascular smooth muscle cell differentiation	2.387260e-3
GO:0051301	cell division	2.389029e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	2.459496e-3
GO:0002554	serotonin secretion by platelet	2.485934e-3
GO:0043163	cell envelope organization	2.485934e-3
GO:0060292	long term synaptic depression	2.510954e-3
GO:0021602	cranial nerve morphogenesis	2.529879e-3
GO:0000819	sister chromatid segregation	2.679702e-3
GO:0071777	positive regulation of cell cycle cytokinesis	2.683704e-3
GO:0021514	ventral spinal cord interneuron differentiation	2.763465e-3
GO:0032107	regulation of response to nutrient levels	2.787327e-3
GO:0021610	facial nerve morphogenesis	2.793043e-3
GO:0021644	vagus nerve morphogenesis	2.880192e-3
GO:0034653	retinoic acid catabolic process	2.880192e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	2.995683e-3
GO:0048102	autophagic cell death	3.045796e-3
GO:0016050	vesicle organization	3.063701e-3
GO:0021527	spinal cord association neuron differentiation	3.066624e-3
GO:0007217	tachykinin receptor signaling pathway	3.144171e-3
GO:0051329	interphase of mitotic cell cycle	3.171029e-3
GO:0048227	plasma membrane to endosome transport	3.218557e-3
GO:0042942	D-serine transport	3.218557e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	3.218557e-3
GO:0034970	histone H3-R2 methylation	3.218557e-3
GO:0045987	positive regulation of smooth muscle contraction	3.223768e-3
GO:0035946	mitochondrial mRNA surveillance	3.227310e-3
GO:0035945	mitochondrial ncRNA surveillance	3.227310e-3
GO:0070827	chromatin maintenance	3.227310e-3
GO:0051545	negative regulation of elastin biosynthetic process	3.227310e-3
GO:0031118	rRNA pseudouridine synthesis	3.227310e-3
GO:0035087	siRNA loading onto RISC involved in RNA interference	3.227310e-3
GO:0000236	mitotic prometaphase	3.227310e-3
GO:0006653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	3.227310e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	3.265329e-3
GO:0008633	activation of pro-apoptotic gene products	3.265329e-3
GO:0008334	histone mRNA metabolic process	3.360503e-3
GO:0060384	innervation	3.391489e-3
GO:0046092	deoxycytidine metabolic process	3.510265e-3
GO:0007181	transforming growth factor beta receptor complex assembly	3.510265e-3
GO:0021516	dorsal spinal cord development	3.514443e-3
GO:0071711	basement membrane organization	3.522635e-3
GO:0060214	endocardium formation	3.522635e-3
GO:0045351	type I interferon biosynthetic process	3.522635e-3
GO:0048148	behavioral response to cocaine	3.522635e-3
GO:0021562	vestibulocochlear nerve development	3.527102e-3
GO:0006398	histone mRNA 3'-end processing	3.527102e-3
GO:0071636	positive regulation of transforming growth factor beta production	3.554480e-3
GO:0006772	thiamine metabolic process	3.561931e-3
GO:0006408	snRNA export from nucleus	3.561931e-3
GO:0048814	regulation of dendrite morphogenesis	3.562932e-3
GO:0034504	protein localization to nucleus	3.574210e-3
GO:0060484	lung-associated mesenchyme development	3.722256e-3
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	3.952207e-3
GO:0007052	mitotic spindle organization	4.016858e-3
GO:0031297	replication fork processing	4.055257e-3
GO:0006463	steroid hormone receptor complex assembly	4.055257e-3
GO:0046037	GMP metabolic process	4.099146e-3
GO:0002651	positive regulation of tolerance induction to self antigen	4.275961e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	4.375991e-3
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	4.463589e-3
GO:0044337	canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis	4.463589e-3
GO:0018242	protein O-linked glycosylation via serine	4.463589e-3
GO:0018243	protein O-linked glycosylation via threonine	4.463589e-3
GO:0006352	transcription initiation, DNA-dependent	4.491555e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	4.498957e-3
GO:0007026	negative regulation of microtubule depolymerization	4.514687e-3
GO:0032364	oxygen homeostasis	4.529739e-3
GO:0051145	smooth muscle cell differentiation	4.588901e-3
GO:0060440	trachea formation	4.626754e-3
GO:0060119	inner ear receptor cell development	4.635953e-3
GO:0032060	bleb assembly	4.647816e-3
GO:0061001	regulation of dendritic spine morphogenesis	4.661844e-3
GO:0006944	cellular membrane fusion	4.680301e-3
GO:0051325	interphase	4.694109e-3
GO:0044319	wound healing, spreading of cells	4.773010e-3
GO:0031507	heterochromatin formation	4.773010e-3
GO:0006013	mannose metabolic process	4.773010e-3
GO:0001824	blastocyst development	4.812626e-3
GO:0046463	acylglycerol biosynthetic process	4.911316e-3
GO:0002576	platelet degranulation	4.915126e-3
GO:0072560	type B pancreatic cell maturation	4.915126e-3
GO:0002904	positive regulation of B cell apoptosis	4.916003e-3
GO:0033205	cell cycle cytokinesis	4.926961e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.065439e-3
GO:0070460	thyroid-stimulating hormone secretion	5.135855e-3
GO:0021561	facial nerve development	5.205663e-3
GO:0070922	small RNA loading onto RISC	5.394728e-3
GO:0046814	virion attachment, binding of host cell surface coreceptor	5.394728e-3
GO:0009229	thiamine diphosphate biosynthetic process	5.394728e-3
GO:0019064	viral envelope fusion with host membrane	5.394728e-3
GO:0014045	establishment of endothelial blood-brain barrier	5.503182e-3
GO:0048285	organelle fission	5.535322e-3
GO:0048284	organelle fusion	5.539837e-3
GO:0050658	RNA transport	5.560272e-3
GO:0021666	rhombomere 5 formation	5.587580e-3
GO:0021660	rhombomere 3 formation	5.587580e-3
GO:0006891	intra-Golgi vesicle-mediated transport	5.612730e-3
GO:0016090	prenol metabolic process	5.839079e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	5.839079e-3
GO:0006337	nucleosome disassembly	5.839079e-3
GO:0006282	regulation of DNA repair	5.841413e-3
GO:0032594	protein transport within lipid bilayer	5.875878e-3
GO:0031572	G2/M transition DNA damage checkpoint	5.910880e-3
GO:0007051	spindle organization	5.962750e-3
GO:0031114	regulation of microtubule depolymerization	6.091433e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	6.115903e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	6.115903e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	6.115903e-3
GO:0071459	protein localization to chromosome, centromeric region	6.115903e-3
GO:0032530	regulation of microvillus organization	6.115903e-3
GO:2000242	negative regulation of reproductive process	6.169919e-3
GO:0009081	branched chain family amino acid metabolic process	6.187684e-3
GO:0006044	N-acetylglucosamine metabolic process	6.187684e-3
GO:2001022	positive regulation of response to DNA damage stimulus	6.202518e-3
GO:0032886	regulation of microtubule-based process	6.433427e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	6.438091e-3
GO:0033239	negative regulation of cellular amine metabolic process	6.530258e-3
GO:0046755	non-lytic virus budding	6.574385e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	6.574385e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	6.574385e-3
GO:0035315	hair cell differentiation	6.574385e-3
GO:0050891	multicellular organismal water homeostasis	6.626908e-3
GO:0032467	positive regulation of cytokinesis	6.697962e-3
GO:0000212	meiotic spindle organization	6.779293e-3
GO:0010869	regulation of receptor biosynthetic process	6.815577e-3
GO:0042711	maternal behavior	6.827808e-3
GO:0035313	wound healing, spreading of epidermal cells	6.990510e-3
GO:0007274	neuromuscular synaptic transmission	7.103094e-3
GO:0042363	fat-soluble vitamin catabolic process	7.225187e-3
GO:0007220	Notch receptor processing	7.264175e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	7.389350e-3
GO:0022614	membrane to membrane docking	7.389350e-3
GO:0008634	negative regulation of survival gene product expression	7.389350e-3
GO:0043242	negative regulation of protein complex disassembly	7.420455e-3
GO:0021801	cerebral cortex radial glia guided migration	7.597232e-3
GO:0031113	regulation of microtubule polymerization	7.681297e-3
GO:0001825	blastocyst formation	7.683524e-3
GO:0006613	cotranslational protein targeting to membrane	7.703092e-3
GO:0048864	stem cell development	7.715973e-3
GO:0043524	negative regulation of neuron apoptosis	7.759734e-3
GO:0006166	purine ribonucleoside salvage	7.781794e-3
GO:0015695	organic cation transport	7.789938e-3
GO:0008333	endosome to lysosome transport	7.881820e-3
GO:0045879	negative regulation of smoothened signaling pathway	7.892237e-3
GO:0018279	protein N-linked glycosylation via asparagine	7.939646e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	8.099144e-3
GO:0018200	peptidyl-glutamic acid modification	8.099144e-3
GO:0090398	cellular senescence	8.182617e-3
GO:0042769	DNA damage response, detection of DNA damage	8.200249e-3
GO:0043149	stress fiber assembly	8.218395e-3
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	8.268346e-3
GO:0046596	regulation of virion penetration into host cell	8.268346e-3
GO:0048790	maintenance of presynaptic active zone structure	8.268346e-3
GO:0009637	response to blue light	8.268346e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	8.268346e-3
GO:0001966	thigmotaxis	8.268346e-3
GO:0000963	mitochondrial RNA processing	8.268346e-3
GO:0006285	base-excision repair, AP site formation	8.268346e-3
GO:0007630	jump response	8.268346e-3
GO:0008049	male courtship behavior	8.268346e-3
GO:0000188	inactivation of MAPK activity	8.404889e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	8.406966e-3
GO:0045759	negative regulation of action potential	8.406966e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	8.406966e-3
GO:0006689	ganglioside catabolic process	8.406966e-3
GO:0021986	habenula development	8.406966e-3
GO:0060434	bronchus morphogenesis	8.472701e-3
GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	8.566250e-3
GO:0008216	spermidine metabolic process	8.566250e-3
GO:0021591	ventricular system development	8.933962e-3
GO:0035344	hypoxanthine transport	9.315326e-3
GO:0042496	detection of diacyl bacterial lipopeptide	9.315326e-3
GO:0070407	oxidation-dependent protein catabolic process	9.315326e-3
GO:0071726	cellular response to diacyl bacterial lipopeptide	9.315326e-3
GO:0043048	dolichyl monophosphate biosynthetic process	9.315326e-3
GO:0035364	thymine transport	9.315326e-3
GO:0000962	positive regulation of mitochondrial RNA catabolic process	9.315326e-3
GO:0000958	mitochondrial mRNA catabolic process	9.315326e-3
GO:0032077	positive regulation of deoxyribonuclease activity	9.315326e-3
GO:0000965	mitochondrial RNA 3'-end processing	9.315326e-3
GO:0015853	adenine transport	9.315326e-3
GO:0015854	guanine transport	9.315326e-3
GO:0002066	columnar/cuboidal epithelial cell development	9.436013e-3
GO:0022403	cell cycle phase	9.478917e-3
GO:0060998	regulation of dendritic spine development	9.594087e-3
GO:0031061	negative regulation of histone methylation	9.700636e-3
GO:0055025	positive regulation of cardiac muscle tissue development	9.867290e-3
GO:0071157	negative regulation of cell cycle arrest	9.939078e-3
GO:0048863	stem cell differentiation	1.005755e-2
GO:0051028	mRNA transport	1.006369e-2
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.010841e-2
GO:0060576	intestinal epithelial cell development	1.010841e-2
GO:0010991	negative regulation of SMAD protein complex assembly	1.013080e-2
GO:0031576	G2/M transition checkpoint	1.019591e-2
GO:0021675	nerve development	1.027573e-2
GO:0008542	visual learning	1.035952e-2
GO:0034614	cellular response to reactive oxygen species	1.060402e-2
GO:0090177	establishment of planar polarity involved in neural tube closure	1.091469e-2
GO:0021793	chemorepulsion of branchiomotor axon	1.091469e-2
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.091469e-2
GO:0046504	glycerol ether biosynthetic process	1.106210e-2
GO:0033483	gas homeostasis	1.127397e-2
GO:0016926	protein desumoylation	1.141759e-2
GO:0010388	cullin deneddylation	1.144458e-2
GO:0030032	lamellipodium assembly	1.151219e-2
GO:0043576	regulation of respiratory gaseous exchange	1.161215e-2
GO:0032446	protein modification by small protein conjugation	1.164548e-2
GO:0071025	RNA surveillance	1.188224e-2
GO:0090239	regulation of histone H4 acetylation	1.188224e-2
GO:0046292	formaldehyde metabolic process	1.188224e-2
GO:0035090	maintenance of apical/basal cell polarity	1.188224e-2
GO:0001787	natural killer cell proliferation	1.188224e-2
GO:0034134	toll-like receptor 2 signaling pathway	1.188224e-2
GO:0045347	negative regulation of MHC class II biosynthetic process	1.208194e-2
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	1.208194e-2
GO:0009313	oligosaccharide catabolic process	1.208194e-2
GO:0015844	monoamine transport	1.213746e-2
GO:0048489	synaptic vesicle transport	1.238713e-2
GO:0009952	anterior/posterior pattern specification	1.250368e-2
GO:0006626	protein targeting to mitochondrion	1.306670e-2
GO:0021571	rhombomere 5 development	1.313198e-2
GO:0045869	negative regulation of retroviral genome replication	1.339261e-2
GO:0046836	glycolipid transport	1.364095e-2
GO:0002442	serotonin secretion involved in inflammatory response	1.364095e-2
GO:0071985	multivesicular body sorting pathway	1.364095e-2
GO:0002003	angiotensin maturation	1.364095e-2
GO:0000415	negative regulation of histone H3-K36 methylation	1.364095e-2
GO:0007090	regulation of S phase of mitotic cell cycle	1.377131e-2
GO:0061384	heart trabecular morphogenesis	1.383112e-2
GO:0051894	positive regulation of focal adhesion assembly	1.390148e-2
GO:0034332	adherens junction organization	1.405930e-2
GO:0051572	negative regulation of histone H3-K4 methylation	1.427283e-2
GO:0021784	postganglionic parasympathetic nervous system development	1.427283e-2
GO:0016246	RNA interference	1.427283e-2
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	1.449211e-2
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	1.449211e-2
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	1.449211e-2
GO:0045091	regulation of retroviral genome replication	1.454001e-2
GO:0030514	negative regulation of BMP signaling pathway	1.455485e-2
GO:2000774	positive regulation of cellular senescence	1.482377e-2
GO:0090402	oncogene-induced senescence	1.482377e-2
GO:0071294	cellular response to zinc ion	1.482377e-2
GO:0035986	senescence-associated heterochromatin focus formation	1.482377e-2
GO:0016485	protein processing	1.485938e-2
GO:0060435	bronchiole development	1.501854e-2
GO:0042501	serine phosphorylation of STAT protein	1.501854e-2
GO:0016180	snRNA processing	1.510124e-2
GO:0000724	double-strand break repair via homologous recombination	1.582636e-2
GO:0021631	optic nerve morphogenesis	1.590166e-2
GO:0048193	Golgi vesicle transport	1.605915e-2
GO:0045176	apical protein localization	1.618790e-2
GO:0016322	neuron remodeling	1.618790e-2
GO:0035025	positive regulation of Rho protein signal transduction	1.637634e-2
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.637634e-2
GO:0032425	positive regulation of mismatch repair	1.671504e-2
GO:0019276	UDP-N-acetylgalactosamine metabolic process	1.671504e-2
GO:0007412	axon target recognition	1.671504e-2
GO:0010816	calcitonin catabolic process	1.676341e-2
GO:0034959	endothelin maturation	1.676341e-2
GO:0010814	substance P catabolic process	1.676341e-2
GO:0007035	vacuolar acidification	1.676341e-2
GO:0022402	cell cycle process	1.690406e-2
GO:0035993	deltoid tuberosity development	1.708499e-2
GO:0010572	positive regulation of platelet activation	1.708499e-2
GO:0072655	establishment of protein localization in mitochondrion	1.709512e-2
GO:0032099	negative regulation of appetite	1.735444e-2
GO:0032508	DNA duplex unwinding	1.772940e-2
GO:0031062	positive regulation of histone methylation	1.772940e-2
GO:0090241	negative regulation of histone H4 acetylation	1.792867e-2
GO:2000655	negative regulation of cellular response to testosterone stimulus	1.792867e-2
GO:0051097	negative regulation of helicase activity	1.792867e-2
GO:0034401	regulation of transcription by chromatin organization	1.792867e-2
GO:0006343	establishment of chromatin silencing	1.792867e-2
GO:0031937	positive regulation of chromatin silencing	1.792867e-2
GO:0032439	endosome localization	1.792867e-2
GO:0050923	regulation of negative chemotaxis	1.801342e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.801342e-2
GO:0008053	mitochondrial fusion	1.807759e-2
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.832940e-2
GO:0003002	regionalization	1.834062e-2
GO:0032096	negative regulation of response to food	1.890157e-2
GO:0018193	peptidyl-amino acid modification	1.931708e-2
GO:0008105	asymmetric protein localization	1.939377e-2
GO:0050975	sensory perception of touch	1.941919e-2
GO:0046716	muscle cell homeostasis	1.964761e-2
GO:0046381	CMP-N-acetylneuraminate metabolic process	1.978007e-2
GO:0031503	protein complex localization	1.982467e-2
GO:0007254	JNK cascade	2.002782e-2
GO:0043101	purine-containing compound salvage	2.008557e-2
GO:0014826	vein smooth muscle contraction	2.008557e-2
GO:0045112	integrin biosynthetic process	2.029758e-2
GO:0032070	regulation of deoxyribonuclease activity	2.029758e-2
GO:0032392	DNA geometric change	2.067966e-2