Novel motif:99

name:	motif99_GYGTSANACG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0019101	female somatic sex determination	5.852615e-10
GO:0042703	menstruation	5.852615e-10
GO:0048075	positive regulation of eye pigmentation	1.417686e-9
GO:0048820	hair follicle maturation	1.776615e-9
GO:0097045	phosphatidylserine exposure on blood platelet	2.934390e-9
GO:0002074	extraocular skeletal muscle development	3.828453e-9
GO:0046602	regulation of mitotic centrosome separation	6.589448e-9
GO:0016577	histone demethylation	9.409624e-9
GO:0046604	positive regulation of mitotic centrosome separation	1.009981e-8
GO:0016197	endosome transport	1.103854e-8
GO:0051898	negative regulation of protein kinase B signaling cascade	1.242746e-8
GO:0090232	positive regulation of spindle checkpoint	1.300326e-8
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.683242e-8
GO:0046607	positive regulation of centrosome cycle	2.376271e-8
GO:0048073	regulation of eye pigmentation	2.827556e-8
GO:0090234	regulation of kinetochore assembly	2.828154e-8
GO:0090169	regulation of spindle assembly	2.828154e-8
GO:0006482	protein demethylation	3.064968e-8
GO:0060384	innervation	5.089808e-8
GO:0060134	prepulse inhibition	6.470599e-8
GO:0070988	demethylation	7.491659e-8
GO:0090304	nucleic acid metabolic process	1.499656e-7
GO:0030237	female sex determination	2.696113e-7
GO:0043484	regulation of RNA splicing	2.869084e-7
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	3.123562e-7
GO:0090224	regulation of spindle organization	3.133419e-7
GO:0000375	RNA splicing, via transesterification reactions	3.359403e-7
GO:0008333	endosome to lysosome transport	3.822477e-7
GO:0060014	granulosa cell differentiation	3.962618e-7
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	4.040543e-7
GO:0090141	positive regulation of mitochondrial fission	4.285524e-7
GO:0000398	nuclear mRNA splicing, via spliceosome	4.329663e-7
GO:0006730	one-carbon metabolic process	7.855999e-7
GO:0042640	anagen	8.968854e-7
GO:0090231	regulation of spindle checkpoint	9.638487e-7
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1.049972e-6
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	1.049972e-6
GO:0018993	somatic sex determination	1.054354e-6
GO:0016070	RNA metabolic process	1.466817e-6
GO:0060216	definitive hemopoiesis	1.538289e-6
GO:0006844	acyl carnitine transport	1.584923e-6
GO:0007041	lysosomal transport	1.780729e-6
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.837745e-6
GO:0051438	regulation of ubiquitin-protein ligase activity	1.970677e-6
GO:0018283	iron incorporation into metallo-sulfur cluster	2.031805e-6
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	2.077460e-6
GO:0050684	regulation of mRNA processing	2.451097e-6
GO:0016032	viral reproduction	2.478223e-6
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.567816e-6
GO:0051443	positive regulation of ubiquitin-protein ligase activity	2.750289e-6
GO:0070345	negative regulation of fat cell proliferation	3.115310e-6
GO:0034776	response to histamine	3.708242e-6
GO:0000413	protein peptidyl-prolyl isomerization	4.408054e-6
GO:0070831	basement membrane assembly	4.498197e-6
GO:0090230	regulation of centromere complex assembly	4.817360e-6
GO:0071843	cellular component biogenesis at cellular level	5.853729e-6
GO:0090140	regulation of mitochondrial fission	5.948182e-6
GO:0034371	chylomicron remodeling	6.574951e-6
GO:0022038	corpus callosum development	7.611534e-6
GO:0022618	ribonucleoprotein complex assembly	7.700052e-6
GO:0022613	ribonucleoprotein complex biogenesis	8.213512e-6
GO:0045022	early endosome to late endosome transport	1.007438e-5
GO:0007034	vacuolar transport	1.028083e-5
GO:2000210	positive regulation of anoikis	1.042925e-5
GO:0010467	gene expression	1.271337e-5
GO:0006837	serotonin transport	1.312354e-5
GO:0044260	cellular macromolecule metabolic process	1.417533e-5
GO:0055025	positive regulation of cardiac muscle tissue development	1.539225e-5
GO:0050746	regulation of lipoprotein metabolic process	1.579532e-5
GO:0060691	epithelial cell maturation involved in salivary gland development	1.633338e-5
GO:0060096	serotonin secretion, neurotransmission	1.633338e-5
GO:0021506	anterior neuropore closure	1.714888e-5
GO:0007181	transforming growth factor beta receptor complex assembly	1.723916e-5
GO:0001510	RNA methylation	1.793204e-5
GO:0006139	nucleobase-containing compound metabolic process	1.865402e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.889528e-5
GO:0043353	enucleate erythrocyte differentiation	1.959057e-5
GO:0042167	heme catabolic process	2.017994e-5
GO:0000724	double-strand break repair via homologous recombination	2.387141e-5
GO:0050747	positive regulation of lipoprotein metabolic process	2.405610e-5
GO:2000096	positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway	2.517957e-5
GO:0007214	gamma-aminobutyric acid signaling pathway	2.648185e-5
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	2.744617e-5
GO:0071826	ribonucleoprotein complex subunit organization	2.882687e-5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.040769e-5
GO:0000725	recombinational repair	3.181018e-5
GO:0035854	eosinophil fate commitment	3.257386e-5
GO:0030222	eosinophil differentiation	3.257386e-5
GO:0071156	regulation of cell cycle arrest	3.309672e-5
GO:0034621	cellular macromolecular complex subunit organization	3.329457e-5
GO:0006907	pinocytosis	3.429940e-5
GO:0018208	peptidyl-proline modification	3.590734e-5
GO:0006457	protein folding	3.896030e-5
GO:0030262	apoptotic nuclear change	4.087831e-5
GO:0008053	mitochondrial fusion	4.106534e-5
GO:0014807	regulation of somitogenesis	4.246284e-5
GO:2000065	negative regulation of cortisol biosynthetic process	4.329072e-5
GO:0032348	negative regulation of aldosterone biosynthetic process	4.329072e-5
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	4.484674e-5
GO:0050883	musculoskeletal movement, spinal reflex action	4.774587e-5
GO:0007386	compartment pattern specification	5.148322e-5
GO:0016926	protein desumoylation	5.378235e-5
GO:0034622	cellular macromolecular complex assembly	5.381246e-5
GO:2000466	negative regulation of glycogen (starch) synthase activity	5.485833e-5
GO:0051340	regulation of ligase activity	5.517570e-5
GO:0048048	embryonic eye morphogenesis	6.379064e-5
GO:0010002	cardioblast differentiation	6.405599e-5
GO:0007021	tubulin complex assembly	6.602235e-5
GO:0035461	vitamin transmembrane transport	6.716370e-5
GO:0051705	behavioral interaction between organisms	7.195799e-5
GO:0071279	cellular response to cobalt ion	7.365742e-5
GO:0010637	negative regulation of mitochondrial fusion	7.365742e-5
GO:0000073	spindle pole body separation	7.365742e-5
GO:0050775	positive regulation of dendrite morphogenesis	7.409453e-5
GO:0051684	maintenance of Golgi location	7.539729e-5
GO:2000178	negative regulation of neural precursor cell proliferation	8.470054e-5
GO:0071695	anatomical structure maturation	9.197326e-5
GO:0007212	dopamine receptor signaling pathway	9.354431e-5
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	1.014768e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.037440e-4
GO:0051444	negative regulation of ubiquitin-protein ligase activity	1.073499e-4
GO:0051351	positive regulation of ligase activity	1.106505e-4
GO:0042637	catagen	1.125740e-4
GO:0060763	mammary duct terminal end bud growth	1.158572e-4
GO:0090002	establishment of protein localization in plasma membrane	1.162578e-4
GO:0000209	protein polyubiquitination	1.181802e-4
GO:0034063	stress granule assembly	1.187647e-4
GO:0072668	tubulin complex biogenesis	1.197532e-4
GO:0043004	cytoplasmic sequestering of CFTR protein	1.219880e-4
GO:0042596	fear response	1.242681e-4
GO:0003264	regulation of cardioblast proliferation	1.324640e-4
GO:0010890	positive regulation of sequestering of triglyceride	1.357571e-4
GO:0010742	macrophage derived foam cell differentiation	1.500587e-4
GO:0000216	M/G1 transition of mitotic cell cycle	1.509442e-4
GO:0021623	oculomotor nerve formation	1.566380e-4
GO:0003409	optic cup structural organization	1.566380e-4
GO:0003404	optic vesicle morphogenesis	1.566380e-4
GO:0070076	histone lysine demethylation	1.623918e-4
GO:0046390	ribose phosphate biosynthetic process	1.629077e-4
GO:0051452	intracellular pH reduction	1.767766e-4
GO:0010741	negative regulation of intracellular protein kinase cascade	1.846128e-4
GO:0031104	dendrite regeneration	1.882564e-4
GO:0071934	thiamine transmembrane transport	1.924244e-4
GO:2000209	regulation of anoikis	1.992450e-4
GO:0070172	positive regulation of tooth mineralization	1.992450e-4
GO:0001964	startle response	2.094444e-4
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	2.106623e-4
GO:0009446	putrescine biosynthetic process	2.147962e-4
GO:0048087	positive regulation of developmental pigmentation	2.216818e-4
GO:0002115	store-operated calcium entry	2.266249e-4
GO:0007221	positive regulation of transcription of Notch receptor target	2.266663e-4
GO:0045851	pH reduction	2.295589e-4
GO:0035967	cellular response to topologically incorrect protein	2.325165e-4
GO:0051181	cofactor transport	2.362444e-4
GO:0030968	endoplasmic reticulum unfolded protein response	2.378245e-4
GO:0032792	negative regulation of CREB transcription factor activity	2.388542e-4
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.439669e-4
GO:0050882	voluntary musculoskeletal movement	2.456992e-4
GO:0060160	negative regulation of dopamine receptor signaling pathway	2.490033e-4
GO:0090104	pancreatic E cell differentiation	2.516041e-4
GO:0003311	pancreatic D cell differentiation	2.516041e-4
GO:0072331	signal transduction by p53 class mediator	2.529372e-4
GO:0045955	negative regulation of calcium ion-dependent exocytosis	2.533598e-4
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	2.572986e-4
GO:0032203	telomere formation via telomerase	2.634208e-4
GO:0045719	negative regulation of glycogen biosynthetic process	2.639210e-4
GO:0034453	microtubule anchoring	2.705120e-4
GO:0007051	spindle organization	2.787901e-4
GO:0010944	negative regulation of transcription by competitive promoter binding	2.884409e-4
GO:0002551	mast cell chemotaxis	2.914114e-4
GO:0006739	NADP metabolic process	2.921942e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	2.952815e-4
GO:0070344	regulation of fat cell proliferation	3.034124e-4
GO:0032874	positive regulation of stress-activated MAPK cascade	3.070277e-4
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	3.227385e-4
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	3.227665e-4
GO:0046755	non-lytic virus budding	3.248882e-4
GO:0006974	response to DNA damage stimulus	3.250237e-4
GO:0001662	behavioral fear response	3.301630e-4
GO:0002543	activation of blood coagulation via clotting cascade	3.403505e-4
GO:0001820	serotonin secretion	3.429750e-4
GO:0000077	DNA damage checkpoint	3.482750e-4
GO:0034976	response to endoplasmic reticulum stress	3.538678e-4
GO:0043414	macromolecule methylation	3.652196e-4
GO:0022601	menstrual cycle phase	3.793253e-4
GO:0034080	CenH3-containing nucleosome assembly at centromere	3.878902e-4
GO:0006479	protein methylation	3.925127e-4
GO:0071281	cellular response to iron ion	3.970667e-4
GO:0090150	establishment of protein localization in membrane	4.029245e-4
GO:0021819	layer formation in cerebral cortex	4.051610e-4
GO:0010878	cholesterol storage	4.263060e-4
GO:0048002	antigen processing and presentation of peptide antigen	4.311045e-4
GO:0002209	behavioral defense response	4.371546e-4
GO:0051647	nucleus localization	4.405731e-4
GO:0035811	negative regulation of urine volume	4.430437e-4
GO:0051453	regulation of intracellular pH	4.616924e-4
GO:0032223	negative regulation of synaptic transmission, cholinergic	4.759974e-4
GO:0045212	neurotransmitter receptor biosynthetic process	4.759974e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	4.759974e-4
GO:0010734	negative regulation of protein glutathionylation	4.759974e-4
GO:0006781	succinyl-CoA pathway	4.759974e-4
GO:0070141	response to UV-A	4.835838e-4
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	4.980660e-4
GO:0070544	histone H3-K36 demethylation	5.125155e-4
GO:0010452	histone H3-K36 methylation	5.195983e-4
GO:0001302	replicative cell aging	5.272351e-4
GO:0070286	axonemal dynein complex assembly	5.301778e-4
GO:0031570	DNA integrity checkpoint	5.319192e-4
GO:0035621	ER to Golgi ceramide transport	5.449065e-4
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	5.449065e-4
GO:0033577	protein glycosylation in endoplasmic reticulum	5.449065e-4
GO:0002554	serotonin secretion by platelet	5.449065e-4
GO:0032774	RNA biosynthetic process	5.491684e-4
GO:0006984	ER-nucleus signaling pathway	5.769336e-4
GO:0017145	stem cell division	5.890990e-4
GO:0051973	positive regulation of telomerase activity	5.901935e-4
GO:0043461	proton-transporting ATP synthase complex assembly	5.932262e-4
GO:0009451	RNA modification	5.971489e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	5.973635e-4
GO:0010889	regulation of sequestering of triglyceride	6.145316e-4
GO:0002089	lens morphogenesis in camera-type eye	6.341420e-4
GO:0045653	negative regulation of megakaryocyte differentiation	6.929460e-4
GO:0030421	defecation	6.963933e-4
GO:0050881	musculoskeletal movement	7.060302e-4
GO:0000075	cell cycle checkpoint	7.128033e-4
GO:0006414	translational elongation	7.151241e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	7.373002e-4
GO:0045652	regulation of megakaryocyte differentiation	7.394340e-4
GO:0048199	vesicle targeting, to, from or within Golgi	7.667746e-4
GO:0006281	DNA repair	8.301672e-4
GO:0051660	establishment of centrosome localization	8.376039e-4
GO:0021540	corpus callosum morphogenesis	8.376039e-4
GO:0006054	N-acetylneuraminate metabolic process	8.376039e-4
GO:0060690	epithelial cell differentiation involved in salivary gland development	8.379377e-4
GO:0031627	telomeric loop formation	8.394371e-4
GO:0006741	NADP biosynthetic process	8.394371e-4
GO:0044258	intestinal lipid catabolic process	8.443997e-4
GO:0018350	protein esterification	8.443997e-4
GO:0051148	negative regulation of muscle cell differentiation	8.638500e-4
GO:0006302	double-strand break repair	8.781848e-4
GO:0030953	astral microtubule organization	8.972909e-4
GO:0048203	vesicle targeting, trans-Golgi to endosome	9.012963e-4
GO:0051610	serotonin uptake	9.012963e-4
GO:0071423	malate transmembrane transport	9.042489e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	9.042489e-4
GO:0015709	thiosulfate transport	9.042489e-4
GO:2000064	regulation of cortisol biosynthetic process	9.047488e-4
GO:0016071	mRNA metabolic process	9.250906e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	9.405218e-4
GO:0001579	medium-chain fatty acid transport	9.587726e-4
GO:0045662	negative regulation of myoblast differentiation	9.706045e-4
GO:0048813	dendrite morphogenesis	1.017642e-3
GO:0034435	cholesterol esterification	1.035582e-3
GO:0032259	methylation	1.046186e-3
GO:0006188	IMP biosynthetic process	1.051499e-3
GO:0033169	histone H3-K9 demethylation	1.107877e-3
GO:0042481	regulation of odontogenesis	1.115238e-3
GO:0032922	circadian regulation of gene expression	1.119221e-3
GO:0006438	valyl-tRNA aminoacylation	1.132918e-3
GO:0007005	mitochondrion organization	1.150633e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.151809e-3
GO:0048148	behavioral response to cocaine	1.211884e-3
GO:0016081	synaptic vesicle docking involved in exocytosis	1.217136e-3
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.222917e-3
GO:0010868	negative regulation of triglyceride biosynthetic process	1.237980e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.268762e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.310310e-3
GO:0000245	spliceosome assembly	1.323437e-3
GO:0031397	negative regulation of protein ubiquitination	1.354788e-3
GO:0006924	activation-induced cell death of T cells	1.395842e-3
GO:0030641	regulation of cellular pH	1.398025e-3
GO:0051177	meiotic sister chromatid cohesion	1.451479e-3
GO:0003219	cardiac right ventricle formation	1.463824e-3
GO:0006509	membrane protein ectodomain proteolysis	1.482669e-3
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.488804e-3
GO:0046958	nonassociative learning	1.501820e-3
GO:0002635	negative regulation of germinal center formation	1.501820e-3
GO:0022027	interkinetic nuclear migration	1.543453e-3
GO:0031398	positive regulation of protein ubiquitination	1.548848e-3
GO:0035572	N-terminal peptidyl-serine dimethylation	1.551206e-3
GO:0035573	N-terminal peptidyl-serine trimethylation	1.551206e-3
GO:0018016	N-terminal peptidyl-proline dimethylation	1.551206e-3
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.551206e-3
GO:0006308	DNA catabolic process	1.569674e-3
GO:0046907	intracellular transport	1.582942e-3
GO:0007588	excretion	1.618974e-3
GO:0001505	regulation of neurotransmitter levels	1.622903e-3
GO:0015844	monoamine transport	1.636812e-3
GO:0003334	keratinocyte development	1.639744e-3
GO:0006839	mitochondrial transport	1.649941e-3
GO:0032202	telomere assembly	1.659864e-3
GO:0006376	mRNA splice site selection	1.675036e-3
GO:0035305	negative regulation of dephosphorylation	1.732732e-3
GO:0070086	ubiquitin-dependent endocytosis	1.760818e-3
GO:0031125	rRNA 3'-end processing	1.761177e-3
GO:0006014	D-ribose metabolic process	1.896569e-3
GO:0048873	homeostasis of number of cells within a tissue	1.901214e-3
GO:0048692	negative regulation of axon extension involved in regeneration	1.955447e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.972442e-3
GO:0009113	purine base biosynthetic process	1.995612e-3
GO:0031055	chromatin remodeling at centromere	2.024901e-3
GO:0021603	cranial nerve formation	2.058252e-3
GO:0070874	negative regulation of glycogen metabolic process	2.058252e-3
GO:0019322	pentose biosynthetic process	2.060774e-3
GO:0042723	thiamine-containing compound metabolic process	2.081340e-3
GO:0010039	response to iron ion	2.138532e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	2.233390e-3
GO:0045654	positive regulation of megakaryocyte differentiation	2.267112e-3
GO:0006903	vesicle targeting	2.283252e-3
GO:0032853	positive regulation of Ran GTPase activity	2.283835e-3
GO:0010509	polyamine homeostasis	2.283835e-3
GO:0006927	transformed cell apoptosis	2.305818e-3
GO:0006885	regulation of pH	2.316502e-3
GO:0033084	regulation of immature T cell proliferation in thymus	2.355080e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	2.370461e-3
GO:0016079	synaptic vesicle exocytosis	2.427056e-3
GO:0008295	spermidine biosynthetic process	2.428730e-3
GO:0070647	protein modification by small protein conjugation or removal	2.447321e-3
GO:0034351	negative regulation of glial cell apoptosis	2.448358e-3
GO:0050860	negative regulation of T cell receptor signaling pathway	2.477076e-3
GO:0006044	N-acetylglucosamine metabolic process	2.515153e-3
GO:0046718	entry of virus into host cell	2.554478e-3
GO:0016226	iron-sulfur cluster assembly	2.578935e-3
GO:0033108	mitochondrial respiratory chain complex assembly	2.628619e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.684795e-3
GO:0051725	protein de-ADP-ribosylation	2.729298e-3
GO:0071872	cellular response to epinephrine stimulus	2.729298e-3
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	2.729298e-3
GO:0002051	osteoblast fate commitment	2.729298e-3
GO:0071158	positive regulation of cell cycle arrest	2.789662e-3
GO:0051972	regulation of telomerase activity	2.807424e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	2.809148e-3
GO:0006788	heme oxidation	2.810312e-3
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	2.814811e-3
GO:0006396	RNA processing	2.815825e-3
GO:0035176	social behavior	2.876175e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	2.943266e-3
GO:0043029	T cell homeostasis	3.002200e-3
GO:0048102	autophagic cell death	3.031883e-3
GO:0085020	protein K6-linked ubiquitination	3.031883e-3
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	3.031883e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	3.073101e-3
GO:0007220	Notch receptor processing	3.085407e-3
GO:0070170	regulation of tooth mineralization	3.152072e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	3.159014e-3
GO:0046814	virion attachment, binding of host cell surface coreceptor	3.163868e-3
GO:0006189	'de novo' IMP biosynthetic process	3.163868e-3
GO:0003014	renal system process	3.258063e-3
GO:0010610	regulation of mRNA stability involved in response to stress	3.263073e-3
GO:0032347	regulation of aldosterone biosynthetic process	3.414122e-3
GO:0045794	negative regulation of cell volume	3.501296e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	3.655806e-3
GO:0035344	hypoxanthine transport	3.655806e-3
GO:0035364	thymine transport	3.655806e-3
GO:0015854	guanine transport	3.655806e-3
GO:0006051	N-acetylmannosamine metabolic process	3.655806e-3
GO:0019303	D-ribose catabolic process	3.655806e-3
GO:0019230	proprioception	3.675709e-3
GO:0048103	somatic stem cell division	3.787810e-3
GO:0006351	transcription, DNA-dependent	3.807416e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	3.829818e-3
GO:0090161	Golgi ribbon formation	3.833986e-3
GO:0043984	histone H4-K16 acetylation	3.833986e-3
GO:0072348	sulfur compound transport	3.921364e-3
GO:0034641	cellular nitrogen compound metabolic process	4.042110e-3
GO:0033238	regulation of cellular amine metabolic process	4.091590e-3
GO:0006869	lipid transport	4.155144e-3
GO:0042118	endothelial cell activation	4.252451e-3
GO:0010107	potassium ion import	4.293170e-3
GO:0021849	neuroblast division in subventricular zone	4.300333e-3
GO:0050725	positive regulation of interleukin-1 beta biosynthetic process	4.352875e-3
GO:0050754	positive regulation of fractalkine biosynthetic process	4.352875e-3
GO:0031081	nuclear pore distribution	4.352875e-3
GO:0006425	glutaminyl-tRNA aminoacylation	4.352875e-3
GO:0043170	macromolecule metabolic process	4.354331e-3
GO:0008380	RNA splicing	4.378045e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	4.406821e-3
GO:0045601	regulation of endothelial cell differentiation	4.525076e-3
GO:0044243	multicellular organismal catabolic process	4.548550e-3
GO:0072661	protein targeting to plasma membrane	4.730445e-3
GO:0007614	short-term memory	4.730743e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	4.745639e-3
GO:0035635	entry of bacterium into host cell	4.855602e-3
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	4.855602e-3
GO:0006021	inositol biosynthetic process	4.855602e-3
GO:0071870	cellular response to catecholamine stimulus	4.914174e-3
GO:0043628	ncRNA 3'-end processing	4.914174e-3
GO:0010923	negative regulation of phosphatase activity	4.970136e-3
GO:0051865	protein autoubiquitination	5.146210e-3
GO:0051187	cofactor catabolic process	5.300699e-3
GO:0032462	regulation of protein homooligomerization	5.437769e-3
GO:0070585	protein localization in mitochondrion	5.469196e-3
GO:0072395	signal transduction involved in cell cycle checkpoint	5.495191e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.595866e-3
GO:0019062	virion attachment to host cell surface receptor	5.639010e-3
GO:0031069	hair follicle morphogenesis	5.728638e-3
GO:0048690	regulation of axon extension involved in regeneration	5.764215e-3
GO:0051648	vesicle localization	5.771804e-3
GO:0051220	cytoplasmic sequestering of protein	5.788774e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	5.843014e-3
GO:0006108	malate metabolic process	5.850952e-3
GO:0016570	histone modification	5.878358e-3
GO:0031576	G2/M transition checkpoint	5.905244e-3
GO:0032287	peripheral nervous system myelin maintenance	5.914100e-3
GO:0033687	osteoblast proliferation	5.941850e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	5.941850e-3
GO:0046784	intronless viral mRNA export from host nucleus	5.976727e-3
GO:0032872	regulation of stress-activated MAPK cascade	6.070405e-3
GO:0050856	regulation of T cell receptor signaling pathway	6.128520e-3
GO:0019693	ribose phosphate metabolic process	6.251071e-3
GO:0010842	retina layer formation	6.252813e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	6.263272e-3
GO:0043623	cellular protein complex assembly	6.278700e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	6.318151e-3
GO:0006261	DNA-dependent DNA replication	6.339539e-3
GO:0071258	cellular response to gravity	6.343827e-3
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	6.343827e-3
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	6.343827e-3
GO:0061044	negative regulation of vascular wound healing	6.343827e-3
GO:0031573	intra-S DNA damage checkpoint	6.343827e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	6.433611e-3
GO:0006855	drug transmembrane transport	6.446547e-3
GO:0016568	chromatin modification	6.525203e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	6.805729e-3
GO:0048532	anatomical structure arrangement	6.874377e-3
GO:0042482	positive regulation of odontogenesis	6.927582e-3
GO:0035883	enteroendocrine cell differentiation	6.977809e-3
GO:0006900	membrane budding	6.993721e-3
GO:0045844	positive regulation of striated muscle tissue development	7.045034e-3
GO:0007035	vacuolar acidification	7.070321e-3
GO:0002003	angiotensin maturation	7.131179e-3
GO:0030150	protein import into mitochondrial matrix	7.154286e-3
GO:0048560	establishment of anatomical structure orientation	7.168683e-3
GO:0047496	vesicle transport along microtubule	7.344325e-3
GO:0071455	cellular response to hyperoxia	7.351689e-3
GO:0032459	regulation of protein oligomerization	7.380351e-3
GO:0021557	oculomotor nerve development	7.537771e-3
GO:0048388	endosomal lumen acidification	7.590013e-3
GO:0021526	medial motor column neuron differentiation	7.590013e-3
GO:0044267	cellular protein metabolic process	7.593472e-3
GO:0000266	mitochondrial fission	7.656168e-3
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	7.716338e-3
GO:0010866	regulation of triglyceride biosynthetic process	7.750497e-3
GO:0000072	M phase specific microtubule process	7.755528e-3
GO:0006369	termination of RNA polymerase II transcription	7.805845e-3
GO:0031396	regulation of protein ubiquitination	7.833424e-3
GO:0033198	response to ATP	7.905604e-3
GO:0006397	mRNA processing	7.919963e-3
GO:0017148	negative regulation of translation	8.034662e-3
GO:0019067	viral assembly, maturation, egress, and release	8.049682e-3
GO:0018027	peptidyl-lysine dimethylation	8.049682e-3
GO:0032848	negative regulation of cellular pH reduction	8.073028e-3
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	8.073028e-3
GO:0021747	cochlear nucleus development	8.073028e-3
GO:0014042	positive regulation of neuron maturation	8.073028e-3
GO:2000249	regulation of actin cytoskeleton reorganization	8.166976e-3
GO:0046605	regulation of centrosome cycle	8.166976e-3
GO:0032507	maintenance of protein location in cell	8.281438e-3
GO:0019064	viral envelope fusion with host membrane	8.519328e-3
GO:0090209	negative regulation of triglyceride metabolic process	8.631780e-3
GO:0006610	ribosomal protein import into nucleus	8.651170e-3
GO:0018023	peptidyl-lysine trimethylation	8.651170e-3
GO:0006901	vesicle coating	8.667576e-3
GO:0060409	positive regulation of acetylcholine metabolic process	8.689056e-3
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	8.729691e-3
GO:0006534	cysteine metabolic process	8.808838e-3
GO:0046878	positive regulation of saliva secretion	8.904808e-3
GO:0097150	neuronal stem cell maintenance	8.941640e-3
GO:0031297	replication fork processing	9.017860e-3
GO:0045618	positive regulation of keratinocyte differentiation	9.089129e-3
GO:0033364	mast cell secretory granule organization	9.261105e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	9.325715e-3
GO:0060456	positive regulation of digestive system process	9.482737e-3
GO:0006740	NADPH regeneration	9.503410e-3
GO:0051661	maintenance of centrosome location	9.520792e-3
GO:0070781	response to biotin	9.520792e-3
GO:0060904	regulation of protein folding in endoplasmic reticulum	9.520792e-3
GO:0035499	carnosine biosynthetic process	9.520792e-3
GO:0010983	positive regulation of high-density lipoprotein particle clearance	9.520792e-3
GO:0021589	cerebellum structural organization	9.520792e-3
GO:0060689	cell differentiation involved in salivary gland development	9.819341e-3
GO:0015853	adenine transport	9.819341e-3
GO:0043985	histone H4-R3 methylation	1.006758e-2
GO:0030187	melatonin biosynthetic process	1.009081e-2
GO:0060611	mammary gland fat development	1.027350e-2
GO:0046173	polyol biosynthetic process	1.027350e-2
GO:0006683	galactosylceramide catabolic process	1.027350e-2
GO:0008629	induction of apoptosis by intracellular signals	1.031140e-2
GO:0070979	protein K11-linked ubiquitination	1.048262e-2
GO:0034645	cellular macromolecule biosynthetic process	1.050015e-2
GO:0003407	neural retina development	1.061831e-2
GO:0008216	spermidine metabolic process	1.066953e-2
GO:0006313	transposition, DNA-mediated	1.066953e-2
GO:0007379	segment specification	1.087304e-2
GO:0001776	leukocyte homeostasis	1.102880e-2
GO:0017121	phospholipid scrambling	1.103020e-2
GO:2000706	negative regulation of dense core granule biogenesis	1.107430e-2
GO:2000798	negative regulation of amniotic stem cell differentiation	1.107430e-2
GO:0048291	isotype switching to IgG isotypes	1.107430e-2
GO:0018364	peptidyl-glutamine methylation	1.107430e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	6.986783e-10
GO:0046985	positive regulation of hemoglobin biosynthetic process	6.986783e-10
GO:0043973	histone H3-K4 acetylation	6.986783e-10
GO:0051865	protein autoubiquitination	2.940070e-9
GO:0006904	vesicle docking involved in exocytosis	3.003167e-9
GO:0070078	histone H3-R2 demethylation	3.591778e-9
GO:0070079	histone H4-R3 demethylation	3.591778e-9
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	3.591778e-9
GO:0071169	establishment of protein localization to chromatin	4.688164e-9
GO:0048278	vesicle docking	2.135861e-8
GO:0016081	synaptic vesicle docking involved in exocytosis	2.150846e-8
GO:0032740	positive regulation of interleukin-17 production	2.844359e-8
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.538682e-8
GO:0060299	negative regulation of sarcomere organization	3.538682e-8
GO:0046984	regulation of hemoglobin biosynthetic process	9.212836e-8
GO:0046605	regulation of centrosome cycle	1.697973e-7
GO:0022406	membrane docking	3.205073e-7
GO:0005976	polysaccharide metabolic process	4.448004e-7
GO:0030203	glycosaminoglycan metabolic process	6.590610e-7
GO:0010824	regulation of centrosome duplication	1.116536e-6
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.814524e-6
GO:0018293	protein-FAD linkage	1.814524e-6
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.561488e-6
GO:0033299	secretion of lysosomal enzymes	2.935207e-6
GO:0006022	aminoglycan metabolic process	4.835454e-6
GO:0034509	centromeric core chromatin assembly	5.680481e-6
GO:0034080	CenH3-containing nucleosome assembly at centromere	5.680481e-6
GO:0032660	regulation of interleukin-17 production	6.050617e-6
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	6.116473e-6
GO:0006367	transcription initiation from RNA polymerase II promoter	8.006985e-6
GO:0071108	protein K48-linked deubiquitination	8.795717e-6
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.045259e-5
GO:0043932	ossification involved in bone remodeling	1.045259e-5
GO:0006913	nucleocytoplasmic transport	1.060159e-5
GO:0060319	primitive erythrocyte differentiation	1.240803e-5
GO:0032819	positive regulation of natural killer cell proliferation	1.661582e-5
GO:0006396	RNA processing	1.885515e-5
GO:0009817	defense response to fungus, incompatible interaction	1.897761e-5
GO:0051169	nuclear transport	2.098209e-5
GO:0006427	histidyl-tRNA aminoacylation	2.114483e-5
GO:0051026	chiasma assembly	2.568968e-5
GO:0019049	evasion of host defenses by virus	2.930238e-5
GO:0018126	protein hydroxylation	3.137210e-5
GO:0009992	cellular water homeostasis	4.250096e-5
GO:0006610	ribosomal protein import into nucleus	4.357937e-5
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.357937e-5
GO:0048692	negative regulation of axon extension involved in regeneration	4.773299e-5
GO:0021849	neuroblast division in subventricular zone	4.773299e-5
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	5.110913e-5
GO:0042231	interleukin-13 biosynthetic process	5.336202e-5
GO:2000256	positive regulation of male germ cell proliferation	5.336202e-5
GO:0006275	regulation of DNA replication	5.830476e-5
GO:0048285	organelle fission	5.883256e-5
GO:0032965	regulation of collagen biosynthetic process	6.288210e-5
GO:0046599	regulation of centriole replication	6.749769e-5
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	6.881456e-5
GO:0019221	cytokine-mediated signaling pathway	7.437498e-5
GO:0070534	protein K63-linked ubiquitination	7.635738e-5
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	8.475802e-5
GO:0034332	adherens junction organization	1.026694e-4
GO:0045062	extrathymic T cell selection	1.056533e-4
GO:0048143	astrocyte activation	1.111071e-4
GO:0032078	negative regulation of endodeoxyribonuclease activity	1.136357e-4
GO:0006922	cleavage of lamin	1.136357e-4
GO:0032312	regulation of ARF GTPase activity	1.137740e-4
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	1.144646e-4
GO:0042866	pyruvate biosynthetic process	1.180290e-4
GO:0006352	transcription initiation, DNA-dependent	1.192905e-4
GO:0006397	mRNA processing	1.364381e-4
GO:0010950	positive regulation of endopeptidase activity	1.407960e-4
GO:0007093	mitotic cell cycle checkpoint	1.440013e-4
GO:0032967	positive regulation of collagen biosynthetic process	1.449582e-4
GO:0007183	SMAD protein complex assembly	1.578015e-4
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.625966e-4
GO:0006044	N-acetylglucosamine metabolic process	1.669122e-4
GO:0061034	olfactory bulb mitral cell layer development	1.769005e-4
GO:0010936	negative regulation of macrophage cytokine production	1.812069e-4
GO:0032816	positive regulation of natural killer cell activation	1.953076e-4
GO:0010614	negative regulation of cardiac muscle hypertrophy	2.016204e-4
GO:0070267	oncosis	2.151227e-4
GO:2000001	regulation of DNA damage checkpoint	2.151227e-4
GO:0090007	regulation of mitotic anaphase	2.182971e-4
GO:0035912	dorsal aorta morphogenesis	2.182971e-4
GO:0030038	contractile actin filament bundle assembly	2.182971e-4
GO:0034421	post-translational protein acetylation	2.182971e-4
GO:0014010	Schwann cell proliferation	2.204650e-4
GO:0007412	axon target recognition	2.204650e-4
GO:0046604	positive regulation of mitotic centrosome separation	2.349462e-4
GO:0007096	regulation of exit from mitosis	2.404723e-4
GO:0019532	oxalate transport	2.428366e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	2.457420e-4
GO:0046463	acylglycerol biosynthetic process	2.458747e-4
GO:0046724	oxalic acid secretion	2.696218e-4
GO:0070370	cellular heat acclimation	2.696218e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	2.696218e-4
GO:0008535	respiratory chain complex IV assembly	2.707590e-4
GO:0003266	regulation of secondary heart field cardioblast proliferation	2.707607e-4
GO:0006366	transcription from RNA polymerase II promoter	2.786750e-4
GO:0008380	RNA splicing	2.851053e-4
GO:0097035	regulation of membrane lipid distribution	2.855079e-4
GO:0006090	pyruvate metabolic process	2.855278e-4
GO:0043486	histone exchange	2.882734e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	2.940238e-4
GO:0007184	SMAD protein import into nucleus	2.940238e-4
GO:0007406	negative regulation of neuroblast proliferation	3.179461e-4
GO:0000375	RNA splicing, via transesterification reactions	3.249902e-4
GO:0060743	epithelial cell maturation involved in prostate gland development	3.348980e-4
GO:0034441	plasma lipoprotein particle oxidation	3.363265e-4
GO:0007288	sperm axoneme assembly	3.462413e-4
GO:0070306	lens fiber cell differentiation	3.873599e-4
GO:0006289	nucleotide-excision repair	3.885465e-4
GO:0032817	regulation of natural killer cell proliferation	4.043158e-4
GO:0021794	thalamus development	4.238602e-4
GO:0008156	negative regulation of DNA replication	4.324379e-4
GO:0000075	cell cycle checkpoint	4.388269e-4
GO:0032012	regulation of ARF protein signal transduction	4.527526e-4
GO:0010735	positive regulation of transcription via serum response element binding	4.565757e-4
GO:0060427	lung connective tissue development	4.565757e-4
GO:0001672	regulation of chromatin assembly or disassembly	4.620876e-4
GO:0000278	mitotic cell cycle	4.872976e-4
GO:0008361	regulation of cell size	4.881705e-4
GO:0015722	canalicular bile acid transport	4.882859e-4
GO:0000733	DNA strand renaturation	4.918156e-4
GO:0043044	ATP-dependent chromatin remodeling	5.017575e-4
GO:0010889	regulation of sequestering of triglyceride	5.064221e-4
GO:0060215	primitive hemopoiesis	5.064221e-4
GO:0044260	cellular macromolecule metabolic process	5.415430e-4
GO:0046784	intronless viral mRNA export from host nucleus	5.724263e-4
GO:0010669	epithelial structure maintenance	5.818022e-4
GO:0001866	NK T cell proliferation	5.818904e-4
GO:0050916	sensory perception of sweet taste	6.059256e-4
GO:0046607	positive regulation of centrosome cycle	6.059256e-4
GO:0060983	epicardium-derived cardiac vascular smooth muscle cell differentiation	6.087620e-4
GO:0043951	negative regulation of cAMP-mediated signaling	6.087620e-4
GO:0038007	netrin-activated signaling pathway	6.210591e-4
GO:0031055	chromatin remodeling at centromere	6.210591e-4
GO:0032069	regulation of nuclease activity	6.327666e-4
GO:0014741	negative regulation of muscle hypertrophy	6.327666e-4
GO:0048535	lymph node development	6.749736e-4
GO:0014916	regulation of lung blood pressure	7.000776e-4
GO:0044246	regulation of multicellular organismal metabolic process	7.286534e-4
GO:0007049	cell cycle	7.348435e-4
GO:0021783	preganglionic parasympathetic nervous system development	7.814575e-4
GO:0046504	glycerol ether biosynthetic process	7.924751e-4
GO:0043415	positive regulation of skeletal muscle tissue regeneration	7.985761e-4
GO:0045216	cell-cell junction organization	8.044411e-4
GO:0090304	nucleic acid metabolic process	8.080757e-4
GO:0000738	DNA catabolic process, exonucleolytic	8.499405e-4
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	8.513495e-4
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	8.519677e-4
GO:0031536	positive regulation of exit from mitosis	8.519677e-4
GO:0070647	protein modification by small protein conjugation or removal	8.736816e-4
GO:0033135	regulation of peptidyl-serine phosphorylation	8.766718e-4
GO:0051142	positive regulation of NK T cell proliferation	9.322679e-4
GO:0051984	positive regulation of chromosome segregation	9.453529e-4
GO:0072537	fibroblast activation	9.453529e-4
GO:0071345	cellular response to cytokine stimulus	9.538091e-4
GO:0046655	folic acid metabolic process	9.735754e-4
GO:0032916	positive regulation of transforming growth factor beta3 production	9.735754e-4
GO:0044140	negative regulation of growth of symbiont on or near host surface	9.866674e-4
GO:0000087	M phase of mitotic cell cycle	1.019308e-3
GO:0016482	cytoplasmic transport	1.026245e-3
GO:0007067	mitosis	1.051678e-3
GO:0070936	protein K48-linked ubiquitination	1.094119e-3
GO:0016575	histone deacetylation	1.096807e-3
GO:0060075	regulation of resting membrane potential	1.186268e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.186268e-3
GO:0032814	regulation of natural killer cell activation	1.191026e-3
GO:0006476	protein deacetylation	1.193862e-3
GO:0010165	response to X-ray	1.198127e-3
GO:0032446	protein modification by small protein conjugation	1.215111e-3
GO:0060742	epithelial cell differentiation involved in prostate gland development	1.225129e-3
GO:0018065	protein-cofactor linkage	1.277026e-3
GO:0006545	glycine biosynthetic process	1.277026e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.282338e-3
GO:0019432	triglyceride biosynthetic process	1.285803e-3
GO:0051451	myoblast migration	1.316315e-3
GO:0006784	heme a biosynthetic process	1.316315e-3
GO:0045162	clustering of voltage-gated sodium channels	1.316315e-3
GO:0006281	DNA repair	1.369511e-3
GO:0018364	peptidyl-glutamine methylation	1.373212e-3
GO:0048034	heme O biosynthetic process	1.373212e-3
GO:0000147	actin cortical patch assembly	1.373212e-3
GO:0071174	mitotic cell cycle spindle checkpoint	1.391152e-3
GO:0050684	regulation of mRNA processing	1.395366e-3
GO:0042482	positive regulation of odontogenesis	1.458075e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	1.470293e-3
GO:0043543	protein acylation	1.530991e-3
GO:0035855	megakaryocyte development	1.623881e-3
GO:0071168	protein localization to chromatin	1.658014e-3
GO:0016998	cell wall macromolecule catabolic process	1.673152e-3
GO:0019048	virus-host interaction	1.680797e-3
GO:0043064	flagellum organization	1.681297e-3
GO:0061381	cell migration in diencephalon	1.685093e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.685093e-3
GO:0061379	inferior colliculus development	1.685093e-3
GO:0042340	keratan sulfate catabolic process	1.685093e-3
GO:0021855	hypothalamus cell migration	1.685093e-3
GO:0061374	mammillothalamic axonal tract development	1.685093e-3
GO:2000297	negative regulation of synapse maturation	1.690702e-3
GO:0035601	protein deacylation	1.696044e-3
GO:0021884	forebrain neuron development	1.717838e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	1.751030e-3
GO:0032781	positive regulation of ATPase activity	1.758231e-3
GO:0048672	positive regulation of collateral sprouting	1.784427e-3
GO:0030091	protein repair	1.784427e-3
GO:0009957	epidermal cell fate specification	1.784427e-3
GO:0016574	histone ubiquitination	1.823825e-3
GO:0070536	protein K63-linked deubiquitination	1.855658e-3
GO:0071156	regulation of cell cycle arrest	1.859137e-3
GO:0014732	skeletal muscle atrophy	1.920650e-3
GO:0043623	cellular protein complex assembly	1.924609e-3
GO:0016568	chromatin modification	1.926226e-3
GO:0032074	negative regulation of nuclease activity	1.950669e-3
GO:0010172	embryonic body morphogenesis	1.983294e-3
GO:0033280	response to vitamin D	2.028305e-3
GO:0060744	mammary gland branching involved in thelarche	2.085732e-3
GO:0045332	phospholipid translocation	2.149211e-3
GO:0048486	parasympathetic nervous system development	2.160018e-3
GO:0009296	flagellum assembly	2.254299e-3
GO:0006605	protein targeting	2.317403e-3
GO:0006974	response to DNA damage stimulus	2.337246e-3
GO:0046633	alpha-beta T cell proliferation	2.398258e-3
GO:0043949	regulation of cAMP-mediated signaling	2.398258e-3
GO:0048679	regulation of axon regeneration	2.519068e-3
GO:0030204	chondroitin sulfate metabolic process	2.533945e-3
GO:0002513	tolerance induction to self antigen	2.544640e-3
GO:0016925	protein sumoylation	2.553972e-3
GO:0006606	protein import into nucleus	2.625067e-3
GO:0007259	JAK-STAT cascade	2.628007e-3
GO:0071104	response to interleukin-9	2.665073e-3
GO:0060061	Spemann organizer formation	2.665073e-3
GO:0070179	D-serine biosynthetic process	2.665073e-3
GO:0032071	regulation of endodeoxyribonuclease activity	2.687261e-3
GO:0016559	peroxisome fission	2.813422e-3
GO:0002031	G-protein coupled receptor internalization	2.822397e-3
GO:0021695	cerebellar cortex development	2.847412e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	2.881902e-3
GO:0001702	gastrulation with mouth forming second	2.909770e-3
GO:0016322	neuron remodeling	3.096999e-3
GO:0007341	penetration of zona pellucida	3.119425e-3
GO:0046532	regulation of photoreceptor cell differentiation	3.137030e-3
GO:0046668	regulation of retinal cell programmed cell death	3.203183e-3
GO:0051276	chromosome organization	3.352061e-3
GO:0051101	regulation of DNA binding	3.413356e-3
GO:0014889	muscle atrophy	3.458358e-3
GO:0017038	protein import	3.468417e-3
GO:0016567	protein ubiquitination	3.529253e-3
GO:0010529	negative regulation of transposition	3.548309e-3
GO:0070383	DNA cytosine deamination	3.548309e-3
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	3.548309e-3
GO:0042481	regulation of odontogenesis	3.575077e-3
GO:0016340	calcium-dependent cell-matrix adhesion	3.605961e-3
GO:0042095	interferon-gamma biosynthetic process	3.605961e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.605961e-3
GO:0006601	creatine biosynthetic process	3.605961e-3
GO:0001830	trophectodermal cell fate commitment	3.605961e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	3.725295e-3
GO:0022403	cell cycle phase	3.775517e-3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.807134e-3
GO:0010467	gene expression	3.887028e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	3.974631e-3
GO:0000053	argininosuccinate metabolic process	3.974631e-3
GO:0043484	regulation of RNA splicing	4.111460e-3
GO:0006418	tRNA aminoacylation for protein translation	4.113833e-3
GO:0006425	glutaminyl-tRNA aminoacylation	4.174048e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	4.207715e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	4.226624e-3
GO:0072107	positive regulation of ureteric bud formation	4.276101e-3
GO:0051592	response to calcium ion	4.292080e-3
GO:0019835	cytolysis	4.383783e-3
GO:0010611	regulation of cardiac muscle hypertrophy	4.383783e-3
GO:0033561	regulation of water loss via skin	4.416645e-3
GO:0045647	negative regulation of erythrocyte differentiation	4.438437e-3
GO:0043117	positive regulation of vascular permeability	4.505699e-3
GO:0015808	L-alanine transport	4.505699e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	4.648564e-3
GO:0035048	splicing factor protein import into nucleus	4.648564e-3
GO:0021564	vagus nerve development	4.675364e-3
GO:0010564	regulation of cell cycle process	4.706965e-3
GO:0035520	monoubiquitinated protein deubiquitination	4.729756e-3
GO:0006654	phosphatidic acid biosynthetic process	4.838715e-3
GO:0043248	proteasome assembly	4.839706e-3
GO:0051340	regulation of ligase activity	4.839985e-3
GO:0006513	protein monoubiquitination	5.002998e-3
GO:0010763	positive regulation of fibroblast migration	5.096356e-3
GO:0045136	development of secondary sexual characteristics	5.220116e-3
GO:0016577	histone demethylation	5.220116e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	5.362306e-3
GO:0042297	vocal learning	5.362306e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	5.362306e-3
GO:0051170	nuclear import	5.391552e-3
GO:0016071	mRNA metabolic process	5.457505e-3
GO:0000266	mitochondrial fission	5.491827e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	5.561527e-3
GO:0046602	regulation of mitotic centrosome separation	5.658984e-3
GO:0005977	glycogen metabolic process	5.696009e-3
GO:0015884	folic acid transport	5.701663e-3
GO:0006302	double-strand break repair	5.786962e-3
GO:0016032	viral reproduction	5.793640e-3
GO:0006998	nuclear envelope organization	5.936641e-3
GO:0060119	inner ear receptor cell development	6.046031e-3
GO:0034622	cellular macromolecular complex assembly	6.047727e-3
GO:0032070	regulation of deoxyribonuclease activity	6.081329e-3
GO:0030997	regulation of centriole-centriole cohesion	6.081329e-3
GO:0044257	cellular protein catabolic process	6.104506e-3
GO:0051301	cell division	6.399489e-3
GO:0072193	ureter smooth muscle cell differentiation	6.481905e-3
GO:0072053	renal inner medulla development	6.602764e-3
GO:0006596	polyamine biosynthetic process	6.602764e-3
GO:0045906	negative regulation of vasoconstriction	6.602764e-3
GO:0006325	chromatin organization	6.627737e-3
GO:0070507	regulation of microtubule cytoskeleton organization	6.821859e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	6.849783e-3
GO:0014743	regulation of muscle hypertrophy	6.872189e-3
GO:0071173	spindle assembly checkpoint	6.885416e-3
GO:0048680	positive regulation of axon regeneration	6.885416e-3
GO:0006659	phosphatidylserine biosynthetic process	6.885416e-3
GO:0060081	membrane hyperpolarization	7.056806e-3
GO:0030212	hyaluronan metabolic process	7.113151e-3
GO:0006473	protein acetylation	7.221353e-3
GO:0032695	negative regulation of interleukin-12 production	7.326018e-3
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.341525e-3
GO:0015791	polyol transport	7.341525e-3
GO:0022415	viral reproductive process	7.343128e-3
GO:2000826	regulation of heart morphogenesis	7.348097e-3
GO:0002070	epithelial cell maturation	7.389239e-3
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	7.433799e-3
GO:0051782	negative regulation of cell division	7.682763e-3
GO:0042350	GDP-L-fucose biosynthetic process	7.682763e-3
GO:0042178	xenobiotic catabolic process	7.698267e-3
GO:0050829	defense response to Gram-negative bacterium	7.731020e-3
GO:0055107	Golgi to secretory granule transport	7.744976e-3
GO:0031468	nuclear envelope reassembly	7.744976e-3
GO:0010826	negative regulation of centrosome duplication	7.744976e-3
GO:0006021	inositol biosynthetic process	7.744976e-3
GO:0051660	establishment of centrosome localization	7.759747e-3
GO:0021540	corpus callosum morphogenesis	7.759747e-3
GO:0072560	type B pancreatic cell maturation	7.759747e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	7.759747e-3
GO:0006421	asparaginyl-tRNA aminoacylation	7.759747e-3
GO:0006429	leucyl-tRNA aminoacylation	7.759747e-3
GO:0090102	cochlea development	7.767506e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	7.780209e-3
GO:0050917	sensory perception of umami taste	7.957844e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	8.140217e-3
GO:0030104	water homeostasis	8.214079e-3
GO:0071072	negative regulation of phospholipid biosynthetic process	8.285493e-3
GO:0031065	positive regulation of histone deacetylation	8.507344e-3
GO:0052200	response to host defenses	8.597496e-3
GO:0035082	axoneme assembly	8.597496e-3
GO:0010891	negative regulation of sequestering of triglyceride	8.597496e-3
GO:0006482	protein demethylation	8.652839e-3
GO:0019255	glucose 1-phosphate metabolic process	8.666869e-3
GO:0000209	protein polyubiquitination	8.676833e-3
GO:0043502	regulation of muscle adaptation	8.707294e-3
GO:0044264	cellular polysaccharide metabolic process	9.078708e-3
GO:0071425	hemopoietic stem cell proliferation	9.094016e-3
GO:0071305	cellular response to vitamin D	9.202601e-3
GO:0033119	negative regulation of RNA splicing	9.223423e-3
GO:0045930	negative regulation of mitotic cell cycle	9.343625e-3
GO:0006906	vesicle fusion	9.442617e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	9.495153e-3
GO:0032928	regulation of superoxide anion generation	9.543757e-3
GO:0048670	regulation of collateral sprouting	9.543757e-3
GO:0071474	cellular hyperosmotic response	9.555282e-3
GO:0021930	cerebellar granule cell precursor proliferation	9.555282e-3
GO:0009070	serine family amino acid biosynthetic process	9.842944e-3
GO:0006290	pyrimidine dimer repair	9.872039e-3
GO:0060710	chorio-allantoic fusion	9.880994e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	1.014039e-2
GO:0060971	embryonic heart tube left/right pattern formation	1.031436e-2
GO:0022408	negative regulation of cell-cell adhesion	1.033289e-2
GO:0034201	response to oleic acid	1.042986e-2
GO:0090312	positive regulation of protein deacetylation	1.043411e-2
GO:0006835	dicarboxylic acid transport	1.043411e-2
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	1.044652e-2
GO:0044265	cellular macromolecule catabolic process	1.079950e-2
GO:0006886	intracellular protein transport	1.083748e-2
GO:0033211	adiponectin-mediated signaling pathway	1.100928e-2
GO:0045987	positive regulation of smooth muscle contraction	1.114810e-2
GO:0060547	negative regulation of necrotic cell death	1.119093e-2
GO:0035811	negative regulation of urine volume	1.123278e-2
GO:0035886	vascular smooth muscle cell differentiation	1.124235e-2
GO:0070498	interleukin-1-mediated signaling pathway	1.134354e-2
GO:0018205	peptidyl-lysine modification	1.153502e-2
GO:0009057	macromolecule catabolic process	1.156184e-2
GO:0007109	cytokinesis, completion of separation	1.157283e-2
GO:0071071	regulation of phospholipid biosynthetic process	1.167365e-2
GO:0051001	negative regulation of nitric-oxide synthase activity	1.167365e-2
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.167365e-2
GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	1.179996e-2
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.179996e-2
GO:0042073	intraflagellar transport	1.179996e-2
GO:0007630	jump response	1.179996e-2
GO:0008049	male courtship behavior	1.179996e-2
GO:0001966	thigmotaxis	1.179996e-2
GO:0034971	histone H3-R17 methylation	1.198290e-2
GO:0033260	DNA replication involved in S phase	1.198290e-2
GO:0006997	nucleus organization	1.210955e-2
GO:0016573	histone acetylation	1.215100e-2
GO:0006096	glycolysis	1.221641e-2
GO:0005975	carbohydrate metabolic process	1.239288e-2
GO:0051894	positive regulation of focal adhesion assembly	1.254754e-2
GO:0045792	negative regulation of cell size	1.263530e-2
GO:0045657	positive regulation of monocyte differentiation	1.263530e-2
GO:0002309	T cell proliferation involved in immune response	1.263530e-2
GO:0034508	centromere complex assembly	1.263530e-2
GO:0071277	cellular response to calcium ion	1.265805e-2
GO:0007224	smoothened signaling pathway	1.285129e-2
GO:0031577	spindle checkpoint	1.292103e-2
GO:0030501	positive regulation of bone mineralization	1.296368e-2
GO:0051901	positive regulation of mitochondrial depolarization	1.300521e-2
GO:0043654	recognition of apoptotic cell	1.300521e-2
GO:0046135	pyrimidine nucleoside catabolic process	1.300521e-2
GO:0048681	negative regulation of axon regeneration	1.318328e-2
GO:0048690	regulation of axon extension involved in regeneration	1.318328e-2
GO:0032119	sequestering of zinc ion	1.318328e-2
GO:0045081	negative regulation of interleukin-10 biosynthetic process	1.318328e-2
GO:0009107	lipoate biosynthetic process	1.335570e-2
GO:0006526	arginine biosynthetic process	1.335570e-2
GO:0021885	forebrain cell migration	1.346533e-2
GO:0009072	aromatic amino acid family metabolic process	1.361039e-2
GO:0006403	RNA localization	1.384933e-2
GO:0034621	cellular macromolecular complex subunit organization	1.392066e-2
GO:0001836	release of cytochrome c from mitochondria	1.403543e-2
GO:0070988	demethylation	1.412746e-2
GO:0006689	ganglioside catabolic process	1.419279e-2
GO:0033962	cytoplasmic mRNA processing body assembly	1.421159e-2
GO:0090403	oxidative stress-induced premature senescence	1.421159e-2
GO:0032910	regulation of transforming growth factor beta3 production	1.421159e-2
GO:0048172	regulation of short-term neuronal synaptic plasticity	1.422514e-2
GO:0050913	sensory perception of bitter taste	1.444618e-2
GO:0034504	protein localization to nucleus	1.473668e-2
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	1.478552e-2
GO:0007339	binding of sperm to zona pellucida	1.482253e-2
GO:0006884	cell volume homeostasis	1.482253e-2
GO:0006821	chloride transport	1.495167e-2
GO:0021860	pyramidal neuron development	1.497655e-2
GO:0045040	protein import into mitochondrial outer membrane	1.512396e-2
GO:0032328	alanine transport	1.512396e-2
GO:0002268	follicular dendritic cell differentiation	1.512396e-2
GO:0031987	locomotion involved in locomotory behavior	1.512396e-2
GO:0032075	positive regulation of nuclease activity	1.512396e-2
GO:0070169	positive regulation of biomineral tissue development	1.517767e-2
GO:0006383	transcription from RNA polymerase III promoter	1.535871e-2
GO:0048733	sebaceous gland development	1.535871e-2
GO:0070537	histone H2A K63-linked deubiquitination	1.535871e-2
GO:0010890	positive regulation of sequestering of triglyceride	1.535871e-2
GO:0032825	positive regulation of natural killer cell differentiation	1.536826e-2
GO:0034645	cellular macromolecule biosynthetic process	1.565539e-2
GO:0006259	DNA metabolic process	1.574428e-2
GO:0007221	positive regulation of transcription of Notch receptor target	1.592614e-2
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.595428e-2
GO:0051028	mRNA transport	1.627362e-2
GO:0048066	developmental pigmentation	1.636261e-2
GO:0051354	negative regulation of oxidoreductase activity	1.652642e-2
GO:0045839	negative regulation of mitosis	1.661077e-2
GO:0008637	apoptotic mitochondrial changes	1.664149e-2
GO:0046543	development of secondary female sexual characteristics	1.682354e-2
GO:0048697	positive regulation of collateral sprouting in absence of injury	1.685740e-2
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	1.685740e-2
GO:0070163	regulation of adiponectin secretion	1.685740e-2
GO:0048478	replication fork protection	1.685740e-2
GO:0000059	protein import into nucleus, docking	1.685740e-2
GO:0006597	spermine biosynthetic process	1.685740e-2
GO:0022029	telencephalon cell migration	1.688266e-2
GO:0046511	sphinganine biosynthetic process	1.691185e-2
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	1.691185e-2
GO:0090177	establishment of planar polarity involved in neural tube closure	1.691185e-2
GO:0046416	D-amino acid metabolic process	1.691185e-2
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1.691185e-2
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.691185e-2
GO:0035633	maintenance of blood-brain barrier	1.691185e-2
GO:0015826	threonine transport	1.691185e-2
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	1.691185e-2
GO:0034589	hydroxyproline transport	1.691185e-2
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.716270e-2
GO:0032747	positive regulation of interleukin-23 production	1.716270e-2
GO:0042384	cilium assembly	1.750674e-2
GO:0021557	oculomotor nerve development	1.767597e-2
GO:0060364	frontal suture morphogenesis	1.774285e-2
GO:0017004	cytochrome complex assembly	1.777048e-2
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.777643e-2
GO:0006863	purine base transport	1.778514e-2
GO:0046716	muscle cell homeostasis	1.785766e-2
GO:0021756	striatum development	1.850009e-2
GO:0043632	modification-dependent macromolecule catabolic process	1.937279e-2
GO:0002344	B cell affinity maturation	1.938763e-2
GO:0000086	G2/M transition of mitotic cell cycle	1.941550e-2
GO:0044267	cellular protein metabolic process	1.957887e-2
GO:0060982	coronary artery morphogenesis	1.979460e-2
GO:0030163	protein catabolic process	1.979902e-2
GO:0043114	regulation of vascular permeability	1.982008e-2
GO:0021702	cerebellar Purkinje cell differentiation	2.024849e-2
GO:0035066	positive regulation of histone acetylation	2.027185e-2
GO:0042401	cellular biogenic amine biosynthetic process	2.036390e-2
GO:2000171	negative regulation of dendrite development	2.042938e-2
GO:0033523	histone H2B ubiquitination	2.043840e-2
GO:0000080	G1 phase of mitotic cell cycle	2.069479e-2