MCL coexpression mm9:10: Difference between revisions
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{{MCL_coexpression_mm9| | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.00958431157578808,-0.000987115043198554,-0.00301622798926326,-0.0034998580119884,-0.0031965065118993,-0.00478748846314393,-0.00408826165980277,-0.0129791791970497,-0.0128902731417956,-0.0115022393366457,-0.0174454050542852,-0.0162365753794144,-0.0154967187504481,-0.0149547930240291,-0.0106277348731295,-0.00933044649713753,-0.0103378939620656,-0.0131557322310572,-0.0146113411642149,-0.0140095612126279,0.0660599798479685,-0.00795262207828516,-0.00876012490935796,-0.00189046108047939,-0.00233109866310464,-0.00182158486799818,-0.00295582586276901,-0.00204715433797264,-0.00418323753468836,-0.00459664707132199,-0.00355106054580922,-0.0102958688836842,-0.00908966474711399,-0.0167107893014644,-0.00840799267589695,-0.00867597970918098,-0.00872042865937663,-0.015991147922845,-0.0174096325303469,-0.0180718753335891,-0.0148251308813262,-0.0157206706873006,-0.0159967833297044,0.00789677505411717,0.00648890500699984,0.00555672703070577,0.00150953425349393,0.0193001122576728,0.0191664556481435,0.019146910719064,0.00977566106671362,0.00794486658503102,-0.013824420534311,-0.0139424152194377,-0.0143375122986382,0.0198031239384928,0.0496458108579141,0.156679854749703,0.000543078488422773,0.00304747877128929,4.85539733171969e-05,-0.00303738948256995,-0.00525125948258402,-0.00740679389604731,-0.00667786215569125,-0.00918273363331061,0.00613363474378393,0.0151633823089167,-0.00361527386782118,-0.00229974468171803,-0.00313190398047351,0.0146338182705064,0.0171461060740771,-0.0038616160539761,-0.00462073464850314,-0.00743561632026232,0.0233986976328745,0.0336048081249471,0.0294037938542773,0.000958008670474589,0.00340871671558598,0.000463665978840624,0.0317894358585901,0.0283457259358586,0.0308381654871771,0.01326068808036,0.0209207749418199,0.00540205208355958,-0.00105679977299799,0.00350865490294112,0.043068350152894,0.0115512072090344,0.00971307895669369,0.0113032141432285,0.0110430304075047,0.00748059390836632,0.148285807582513,0.0015110129191619,0.00330467368113512,-0.00113937923996546,0.0171830393308518,-0.00559941706899865,-0.00790407780826537,-0.00664771164336786,-0.000405053915401241,-0.00286090945603682,0.00100426606921655,0.053157054429718,0.00018855395719461,0.0377974459723687,0.0137340225857542,0.0266430992394856,0.0282276923936879,0.0280326210757716,0.0456978712571639,0.0380892383130752,0.033601212216051,0.119018307050255,0.0637552524498486,0.12885889901021,0.124531055356514,0.100833908490472,0.0181736270196607,0.03963686905331,0.0442505317912221,0.0110006738696149,-0.0119683179464199,-0.0133782678484826,-0.0128524975477308,0.0339957702885944,0.026767017731307,0.00633198033396196,0.0310934013356955,0.0286285253101387,0.03789678409773,0.0341916129853111,0.0166056346148343,0.07399494745704,0.0189932412891771,0.0716728960181089,0.00627671504121337,0.0131739245428931,0.0185313169694892,0.0319252973172063,0.0349019560009527,0.0364948669190771,0.0368665014998489,0.0870908127416037,-0.00630202910048118,0.00841425430934886,0.0105668058081909,0.0195136696776698,0.0178882816673829,0.0459682279129972,0.035662090953759,0.0101797368007448,-0.0144603612225725,-0.0149542586771256,-0.0127000862238483,0.197208946251055,0.227233978506864,0.247268116500414,0.261059134610337,0.318082871726653,0.372105741237139,0.454309097002798,0.479896144588665,0.562775611243834,0.611940257545452,0.829238093737747,0.906839295259765,0.999181320947465,0.943381224175587,0.95260587966602,0.0251598293642987,0.00538134160249912,0.00172709444063609,0.00527289149942099,0.00790043016671167,0.00870187119167042,0.0124669421960036,0.0117907082415519,0.0124747449936756,0.0149241418215423,0.018884717850961,0.0183448094954714,0.0245545612527098,0.0210112893917666,0.0231395397718447,0.0128857301170468,0.0192941303229359,0.0197835786213939,0.00222151687110682,0.0162134304668083,0.0106728528496192,0.0552275511139355,0.0184007150520261,0.0255521170413575,0.0375234759945615,0.0454918926447857,0.0506307546901529,0.0482028260676525,0.0178501746447481,0.0168639464809371,-0.00298790981392986,-0.00498019363660885,-0.000171247653295966,0.000622398211461959,0.00881723868728629,0.00843909307490199,0.0160088523967485,0.0184409033527397,0.0422832484528689,0.0239149751203887,0.0347466266959235,0.0184412177419446,0.0452251596149546,0.0214268535863113,0.0864876414998216,0.0450678693050263,0.0352669073774298,0.0364506595763402,0.0230036432111493,0.0621576010720833,0.0661402841005705,0.0705334560060385,0.0734272743569225,0.0695370909935454,0.0790854104729153,0.112698646812059,0.108140719340973,0.09262216348616,-0.012383092450937,-0.00850245833088028,0.0203659213034054,0.0210488587295069,0.0435905678579157,0.0386810575090137,-0.00703358031354118,0.225173902440377,0.00655897962624746,0.00786063533106531,0.00995778219838604,0.00173243573980084,0.00611938528200804,0.00392934211035644,0.00491125828247489,0.00899172706862105,0.00680241956862694,0.029501524198454,0.0377435467944681,0.0223336699926331,0.0248071199881161,0.03107507336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contraction;4.6429516680018e-08;11938,17888,11548,18821,17906,21954,16511,15464,108058!GO:0003015;heart process;4.6429516680018e-08;11938,17888,11548,18821,17906,21954,16511,15464,108058!GO:0016529;sarcoplasmic reticulum;2.81366407675499e-07;20224,12373,11938,11733,238161,15464,18821!GO:0006936;muscle contraction;3.77186247013164e-07;12373,12288,11938,17888,16985,21954,17930,16511,108058,238871!GO:0003012;muscle system process;3.77186247013164e-07;12373,12288,11938,17888,16985,21954,17930,16511,108058,238871!GO:0016528;sarcoplasm;4.02397282336085e-07;20224,12373,11938,11733,238161,15464,18821!GO:0005856;cytoskeleton;4.02397282336085e-07;170731,17897,66734,16562,226251,17906,22428,20411,11733,237560,20739,26416,93677,17888,16651,225288,59006,21954,225115,27428,17930,13518,238871!GO:0008015;blood circulation;8.00460589934371e-07;12288,11938,17888,11548,18821,17906,21954,16511,15464,108058!GO:0003013;circulatory system process;8.00460589934371e-07;12288,11938,17888,11548,18821,17906,21954,16511,15464,108058!GO:0008016;regulation of heart contraction;1.87474120082947e-06;21954,11938,17888,16511,11548,15464,18821!GO:0015629;actin cytoskeleton;5.58798492625664e-05;17897,17888,226251,59006,17906,21954,22428,17930,20411,20739,13518!GO:0007507;heart development;0.000149194663807349;12373,17888,12166,11548,17189,12154,18821,17906,21954,218772!GO:0006810;transport;0.00023249115811724;80906,11304,67473,16562,22359,63959,67863,16514,71795,16511,108058,20224,20536,17888,18738,12856,100705,69608,11938,12288,18821,12895,18115,20411,11733,71699,11732,12391,13340,17189,20271,20191,12491,13518,11785,58194!GO:0030016;myofibril;0.000233028500654032;21954,17930,26549,12955,17888,59006,17906!GO:0002026;regulation of the force of heart contraction;0.000233028500654032;11938,17888,11548,18821!GO:0005737;cytoplasm;0.000233028500654032;192166,14228,67863,223864,237560,20739,14200,71795,16511,108058,235339,68087,67414,74591,225288,225115,67839,14199,238161,238871,83456,170731,226251,18821,18115,20411,11733,50935,224650,76357,12391,21954,27428,26549,106869,13518,51798,12373,16562,66734,26414,68342,17906,22428,329251,26416,27393,20224,67269,70266,73316,17888,16651,14081,17930,243547,18738,19245,12856,100705,11938,69582,12895,12955,12865,83679,59006,50754,15464,58194!GO:0043292;contractile fiber;0.000233028500654032;21954,17930,26549,12955,17888,59006,17906!GO:0006811;ion transport;0.000233028500654032;80906,12288,11938,18821,18115,11733,16514,16511,108058,71699,11732,12391,20536,20271,20191,12856!GO:0006941;striated muscle contraction;0.000233028500654032;21954,17930,12373,17888,108058!GO:0051234;establishment of localization;0.000350459826314133;80906,11304,67473,16562,22359,63959,67863,16514,71795,16511,108058,20224,20536,17888,18738,12856,100705,69608,11938,12288,18821,12895,18115,20411,11733,71699,11732,12391,13340,17189,20271,20191,12491,13518,11785,58194!GO:0006812;cation transport;0.000350459826314133;80906,12288,11938,12391,20271,20191,18821,18115,11733,16514,16511,108058,71699,12856!GO:0051179;localization;0.000513940083245913;80906,11304,67473,16562,14228,22359,63959,67863,16514,71795,16511,74762,108058,20224,20536,17888,18738,12856,100705,69608,11938,12288,226251,18821,12895,18115,20411,11733,71699,11732,12391,13340,17189,20271,20191,12491,13518,11785,58194!GO:0007517;muscle development;0.000515180871597746;83456,12391,17888,18821,17906,17930,218772,12955,26416!GO:0007275;multicellular organismal development;0.00074956042792845;12373,14228,17906,68337,16419,20739,26416,74762,67269,67414,17888,12166,14164,17930,67839,14199,12589,83456,12288,170731,21748,226251,18821,12955,11732,22340,12391,11548,17189,21407,12154,21954,27428,218772,11785!GO:0030017;sarcomere;0.0008411522096248;21954,17930,26549,12955,17888,59006!GO:0044449;contractile fiber part;0.00104128268748163;21954,17930,26549,12955,17888,59006!GO:0006816;calcium ion transport;0.00104128268748163;12288,11938,12391,20191,108058,18821!GO:0003779;actin binding;0.00143393690865254;17888,16985,225288,226251,21954,27428,225115,20739,93677,13518!GO:0030315;T-tubule;0.00189487480275978;12288,12391,108058!GO:0044429;mitochondrial part;0.00257313113952052;235339,170731,67414,74591,68342,67863,18115,12895,12865,27393,12856!GO:0030029;actin filament-based process;0.00268266449003746;17888,225288,17906,27428,225115,20411,20739,11785!GO:0042383;sarcolemma;0.00299813715090446;12288,12391,16651,108058!GO:0007010;cytoskeleton organization and biogenesis;0.00316249990497359;17897,17888,16562,16985,225288,226251,17906,225115,27428,20411,20739,11785,13518!GO:0030001;metal ion transport;0.00333798723030239;80906,12288,11938,12391,20271,20191,18821,16514,16511,108058,12856!GO:0051239;regulation of multicellular organismal process;0.00366158852718216;12373,12288,11938,17888,11548,18821,21954,16511,15464,11732!GO:0015674;di-, tri-valent inorganic cation transport;0.00399504116334071;12288,11938,12391,20191,108058,18821!GO:0044444;cytoplasmic part;0.00462022734316054;51798,12373,192166,26414,66734,16562,68342,17906,67863,22428,237560,20739,27393,20224,235339,67414,17888,73316,74591,14081,17930,67839,238161,19245,12856,100705,11938,170731,18821,12895,18115,11733,12955,50935,12865,83679,12391,59006,21954,26549,50754,15464,13518!GO:0055074;calcium ion homeostasis;0.0047109538347365;21954,12288,11938,15464,18821!GO:0022892;substrate-specific transporter activity;0.0047109538347365;80906,12288,11938,11304,22359,63959,16514,71795,12865,16511,71699,11732,20536,13340,17189,20271,20191!GO:0048731;system development;0.00532008251220623;83456,12373,170731,226251,18821,17906,68337,12955,20739,26416,74762,11732,22340,67269,12391,17888,11548,12166,14164,17189,12154,21954,27428,17930,218772,67839,11785!GO:0005886;plasma membrane;0.00532008251220623;80906,12288,11304,26414,12554,22359,63959,20411,16419,12955,16514,16511,74762,108058,11732,11512,12391,20536,13340,16651,20271,12491,27428,20927,243547,56788,13518,58194,16155!GO:0032502;developmental process;0.00542149498915157;12373,14228,17906,68337,16419,20739,26416,74762,67269,67414,17888,12166,14164,16985,17930,67839,14199,12589,83456,12288,170731,21748,226251,11790,18821,12955,11732,22340,12391,11548,17189,21407,12154,12491,21954,27428,218772,106869,11785,58194!GO:0055065;metal ion homeostasis;0.00698688230142236;21954,12288,11938,15464,18821!GO:0031975;envelope;0.00767802064211943;170731,67414,74591,68342,67863,18115,12895,12865,16511,238161,12856!GO:0031967;organelle envelope;0.00767802064211943;170731,67414,74591,68342,67863,18115,12895,12865,16511,238161,12856!GO:0030036;actin cytoskeleton organization and biogenesis;0.00773130363001897;225115,27428,20411,20739,17888,225288,17906!GO:0008217;regulation of blood pressure;0.00843999871292809;21954,12288,17888,11548!GO:0005740;mitochondrial envelope;0.0095486124423667;170731,67414,74591,68342,67863,12895,18115,12865,12856!GO:0032787;monocarboxylic acid metabolic process;0.0095486124423667;51798,235339,14081,12895,14120,26416,108079,329065!GO:0015858;nucleoside transport;0.0095486124423667;13340,63959!GO:0008053;mitochondrial fusion;0.0095486124423667;170731,67414!GO:0008092;cytoskeletal protein binding;0.0105501906601928;17888,16985,225288,226251,21954,27428,225115,20739,93677,13518!GO:0005741;mitochondrial outer membrane;0.0110513315443557;12895,170731,67414!GO:0043228;non-membrane-bound organelle;0.0117825612449189;170731,17897,66734,16562,226251,17906,22428,20411,11733,237560,20739,26416,93677,27393,17888,16651,225288,59006,21954,225115,27428,17930,238871,13518!GO:0043232;intracellular non-membrane-bound organelle;0.0117825612449189;170731,17897,66734,16562,226251,17906,22428,20411,11733,237560,20739,26416,93677,27393,17888,16651,225288,59006,21954,225115,27428,17930,238871,13518!GO:0019867;outer membrane;0.0119609250927756;12895,170731,67414,11732!GO:0022857;transmembrane transporter activity;0.0129217654210232;80906,12288,11938,11304,67473,63959,16514,12865,16511,71699,11732,13340,20536,20271,20191!GO:0065008;regulation of biological quality;0.0134598061550316;12288,11938,12391,11304,17888,11548,18821,21954,225115,20739,15464,11785,16155!GO:0016909;SAP kinase activity;0.0137179722067018;26416,26414!GO:0031968;organelle outer membrane;0.0145539192326834;12895,170731,67414!GO:0007632;visual behavior;0.0145539192326834;12288,11548,11785!GO:0008542;visual learning;0.0145539192326834;12288,11548,11785!GO:0048513;organ development;0.0149208476033745;83456,12373,170731,18821,17906,68337,12955,20739,26416,11732,22340,67269,12391,11548,12166,17888,14164,17189,12154,21954,17930,218772!GO:0005739;mitochondrion;0.0152587431059341;51798,192166,170731,26414,68342,67863,18115,12895,22428,237560,12865,27393,235339,67414,74591,14081,12856!GO:0044255;cellular lipid metabolic process;0.0175422262649736;51798,12391,11304,22359,14081,12895,22428,50935,26416,71795,108079,329065!GO:0045822;negative regulation of heart contraction;0.0175422262649736;11938,18821!GO:0048284;organelle fusion;0.0175422262649736;170731,67414!GO:0005337;nucleoside transmembrane transporter activity;0.0175422262649736;13340,63959!GO:0005509;calcium ion binding;0.0180265685012877;80906,12373,12288,11938,17897,73316,12554,22359,17906,225115,26549,20739,56788,13518!GO:0031966;mitochondrial membrane;0.0180265685012877;170731,67414,74591,68342,12895,18115,67863,12865!GO:0006996;organelle organization and biogenesis;0.0185433915663281;21748,170731,17897,16562,226251,17906,22428,20411,20739,27393,67414,17888,225288,16985,225115,27428,67956,13518,11785!GO:0016459;myosin complex;0.0202089473164295;17930,17897,17888,17906!GO:0044430;cytoskeletal part;0.0202089473164295;17897,17888,66734,16562,17906,21954,27428,22428,17930,20411,20739,26416!GO:0022891;substrate-specific transmembrane transporter activity;0.0202089473164295;80906,12288,11938,20536,13340,20271,63959,20191,16514,12865,16511,71699,11732!GO:0055066;di-, tri-valent inorganic cation homeostasis;0.0206083150162924;21954,12288,11938,15464,18821!GO:0015932;nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity;0.0216439003786112;13340,63959!GO:0006874;cellular calcium ion homeostasis;0.0218855038685561;21954,12288,11938,18821!GO:0048856;anatomical structure development;0.022723554951081;83456,12373,12288,170731,226251,18821,17906,68337,12955,20739,26416,74762,11732,22340,67269,12391,17888,11548,12166,14164,17189,12154,21954,27428,17930,218772,67839,11785!GO:0042593;glucose homeostasis;0.0230271862906976;12288,12391,11548!GO:0033500;carbohydrate homeostasis;0.0230271862906976;12288,12391,11548!GO:0048878;chemical homeostasis;0.024639843501122;21954,12288,11938,12391,11548,15464,18821!GO:0051146;striated muscle cell differentiation;0.024639843501122;218772,17888,17906!GO:0030018;Z disc;0.0269009990825435;26549,12955,59006!GO:0055080;cation homeostasis;0.0269597320508764;21954,12288,11938,15464,18821!GO:0006631;fatty acid metabolic process;0.0293309550517837;51798,12895,26416,108079,329065,14081!GO:0006875;cellular metal ion homeostasis;0.0294704102782323;21954,12288,11938,18821!GO:0007005;mitochondrion organization and biogenesis;0.0308016471077186;22428,170731,67414,27393!GO:0005901;caveola;0.0308479412344508;12288,12391!GO:0048738;cardiac muscle development;0.0308479412344508;17888,18821!GO:0007512;adult heart development;0.0308479412344508;17888,11548!GO:0046873;metal ion transmembrane transporter activity;0.0313575952518655;80906,12288,11938,16514,16511,20271,20191!GO:0006937;regulation of muscle contraction;0.0321774833985362;21954,12373,11938!GO:0050801;ion homeostasis;0.0323595563685176;21954,12288,11938,12391,15464,18821!GO:0005244;voltage-gated ion channel activity;0.0326689386268836;80906,12288,16514,16511,20271!GO:0022832;voltage-gated channel activity;0.0326689386268836;80906,12288,16514,16511,20271!GO:0000267;cell fraction;0.0327673981371895;12288,11938,12391,11548,22359,14081,76142,12955,16511,58194,329065!GO:0031674;I band;0.0327673981371895;26549,12955,59006!GO:0045121;lipid raft;0.0327673981371895;20411,12391,74762!GO:0022843;voltage-gated cation channel activity;0.0327673981371895;12288,16514,16511,20271!GO:0002027;regulation of heart rate;0.0343345324499743;17888,11548!GO:0005246;calcium channel regulator activity;0.0343345324499743;21954,18821!GO:0006629;lipid metabolic process;0.0366289343952199;51798,12391,11304,22359,14081,12895,22428,50935,26416,71795,108079,329065!GO:0014706;striated muscle development;0.0388382010009254;218772,26416,17888,18821,17906!GO:0001976;regulation of systemic arterial blood pressure by neurological process;0.0402070325277714;21954,11548!GO:0015075;ion transmembrane transporter activity;0.0424482973364429;80906,12288,11938,20536,20271,20191,16514,12865,16511,11732,71699!GO:0005624;membrane fraction;0.0427670422180957;12288,11938,12391,11548,22359,14081,76142,16511,58194,329065!GO:0005515;protein binding;0.0427670422180957;26414,66734,76612,14228,12554,17906,22428,237560,16419,20739,26416,14200,93677,23994,108058,235339,67414,17888,73316,14164,16985,225288,218763,225115,243547,319476,238161,11938,12288,170731,226519,18575,226251,18821,20411,11733,71699,22340,12391,80903,434246,20191,12154,12491,21954,27428,109245,50754,56788,13518,11785,58194,16155!GO:0005261;cation channel activity;0.0427670422180957;80906,12288,16514,16511,20271,20191!GO:0035265;organ growth;0.0454853305193667;12288,11548!GO:0048646;anatomical structure formation;0.0473409537361205;21954,22340,67269,170731,26416,14164!GO:0008324;cation transmembrane transporter activity;0.0478631726360756;80906,12288,11938,20271,20191,16514,12865,16511,71699!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0007100!2.95e-50!18;UBERON:0000948!2.95e-50!18;UBERON:0005498!2.95e-50!18;UBERON:0004140!2.95e-50!18;UBERON:0009881!2.95e-50!18;UBERON:0004141!2.95e-50!18;UBERON:0003084!2.95e-50!18;UBERON:0007005!2.95e-50!18;UBERON:0004139!2.95e-50!18;UBERON:0004291!2.95e-50!18;UBERON:0004535!8.63e-39!23;UBERON:0001009!8.63e-39!23;UBERON:0004872!2.90e-26!33;UBERON:0003103!1.50e-19!43;UBERON:0003914!1.16e-17!47;UBERON:0003081!2.66e-08!87;UBERON:0010314!1.06e-07!92;UBERON:0000025!1.09e-07!114;UBERON:0004111!5.54e-07!122|tfbs_overrepresentation_for_novel_motifs=1.38135e-05,0.301224,0.00171326,1.09005,3.60708,0.0317872,0.0115936,1.56393,2.73931,2.51863e-06,0.000290989,0.421384,0.000183611,0.0919761,1.37023,0,0.000251386,0.0416629,0.757315,1.84158,1.13654,1.06752,0.00093169,0.758415,0.0084148,0.107934,1.07112,0.0865759,0.824086,0.373883,0.112338,0.662968,0.00882778,0.523263,5.52634e-05,0.306165,1.10869e-12,0.152936,2.87669,0.000944396,0.977375,0.00287498,3.74553,0.393401,0.145605,0.0144691,0.0528699,0.0507024,9.24422,0.0152537,0.0712541,0.00187508,1.77108,0.00509502,0.0625333,0.0233099,2.51799,0.0298492,2.73557,0.00219908,0.0661232,0.000776027,1.44668,0.00465782,0.00640267,0.0147973,0.935329,0.70263,0.060732,0.0978139,1.29693e-06,0.255477,8.67895e-16,0.757802,1.71187e-10,0.0279904,3.40564,0.000460977,0.152513,0.538268,0.951426,0.00047771,0.227501,4.62078e-05,0.00116061,0,7.47431e-08,0.635793,0.00626519,0.302882,0.00871748,0.0576443,0.495386,1.7129,8.87039e-05,1.22522,1.02604,5.24967e-05,0.0364125,0.00602572,0.0553121,0.430368,0.00880528,0.1401,0.0195434,6.17863e-06,4.78511e-05,0.269298,0.0505744,1.33094e-09,0.0749473,0.238696,0.302523,0.0349983,0.216077,2.02822,5.68449e-09,0.000146992,0.0485396,0.187629,0.165109,0.102578,0.183783,0.106756,2.1442,0.0514599,0.595785,0.00314146,0.00988006,0.189301,0.480767,2.49205,0.131496,0.658948,0.56095,0.0458394,0.732031,0.0680417,0.0971402,0.503852,0.261812,0.111807,0.14839,0.600467,0.34702,0.00184839,0.987293,0.147819,6.54699,8.80546e-06,0.397456,0,0.201588,0.03162,1.94894,0.0459719,0.0233724,1.34137,0.0889072,3.35721e-07,0.00167726,0.264206,1.50963,0.253442,2.61802,2.50106,0.120042,1.2688,0.00190692|tfbs_overrepresentation_jaspar=MA0003.1;0,MA0004.1;0.000629943,MA0006.1;3.40313e-07,MA0007.1;0.269044,MA0009.1;0.139516,MA0014.1;0,MA0017.1;1.63797,MA0019.1;0.605292,MA0024.1;0.00021933,MA0025.1;0.1254,MA0027.1;0.52099,MA0028.1;1.79558e-13,MA0029.1;0.268343,MA0030.1;0.222161,MA0031.1;0.700592,MA0038.1;0.392239,MA0040.1;0.231152,MA0041.1;0.00160163,MA0042.1;0.0568794,MA0043.1;0.55478,MA0046.1;0.107339,MA0048.1;0.024783,MA0050.1;0.0120729,MA0051.1;0.0125207,MA0052.1;22.2935,MA0055.1;0.304438,MA0056.1;0,MA0057.1;1.4833e-07,MA0058.1;0.00035066,MA0059.1;0.0460513,MA0060.1;1.06315e-10,MA0061.1;6.48818e-06,MA0063.1;0,MA0066.1;1.28581,MA0067.1;0.0279066,MA0068.1;0.00508757,MA0069.1;0.692226,MA0070.1;0.227441,MA0071.1;9.54657,MA0072.1;1.6082,MA0073.1;0,MA0074.1;2.84858,MA0076.1;2.16974e-15,MA0077.1;1.78966,MA0078.1;1.09155,MA0081.1;0.116049,MA0083.1;4.1413,MA0084.1;0.348226,MA0087.1;0.365588,MA0088.1;0.000231894,MA0089.1;0,MA0090.1;6.65747,MA0091.1;0.915994,MA0092.1;2.78687,MA0093.1;3.51633e-05,MA0095.1;0,MA0098.1;0,MA0100.1;0.0264057,MA0101.1;0.000290099,MA0103.1;0.0967542,MA0105.1;1.4355e-05,MA0106.1;0.043564,MA0107.1;0.000204905,MA0108.2;0.921089,MA0109.1;0,MA0111.1;0.551571,MA0113.1;1.50875,MA0114.1;0.895141,MA0115.1;1.72969,MA0116.1;0.00275053,MA0117.1;0.543711,MA0119.1;1.37482,MA0122.1;2.38133,MA0124.1;0.218493,MA0125.1;0.0291103,MA0130.1;0,MA0131.1;0.000791863,MA0132.1;0,MA0133.1;0,MA0135.1;0.0344988,MA0136.1;0.00504602,MA0139.1;3.18299e-05,MA0140.1;6.19102,MA0141.1;16.8062,MA0142.1;0.188631,MA0143.1;0.601187,MA0144.1;0.976876,MA0145.1;0.0153946,MA0146.1;2.33274e-10,MA0147.1;0.000210043,MA0148.1;1.93109,MA0149.1;7.49926,MA0062.2;0,MA0035.2;12.2193,MA0039.2;0,MA0138.2;0.427937,MA0002.2;0.121616,MA0137.2;0.251089,MA0104.2;1.93522e-05,MA0047.2;1.44641,MA0112.2;1.15088,MA0065.2;1.40414,MA0150.1;6.23726,MA0151.1;0,MA0152.1;1.59677,MA0153.1;0.392392,MA0154.1;1.1884,MA0155.1;0.0549736,MA0156.1;6.96435e-05,MA0157.1;0.255874,MA0158.1;0,MA0159.1;4.76937,MA0160.1;7.84936,MA0161.1;0,MA0162.1;0,MA0163.1;0,MA0164.1;0.154343,MA0080.2;0.000346869,MA0018.2;0.00279922,MA0099.2;0.318451,MA0079.2;0,MA0102.2;0.0935531,MA0258.1;5.95371,MA0259.1;8.37243e-09,MA0442.1;0}} | ||
Latest revision as of 14:29, 17 September 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0060047 | heart contraction | 4.6429516680018e-08 |
| GO:0003015 | heart process | 4.6429516680018e-08 |
| GO:0016529 | sarcoplasmic reticulum | 2.81366407675499e-07 |
| GO:0006936 | muscle contraction | 3.77186247013164e-07 |
| GO:0003012 | muscle system process | 3.77186247013164e-07 |
| GO:0016528 | sarcoplasm | 4.02397282336085e-07 |
| GO:0005856 | cytoskeleton | 4.02397282336085e-07 |
| GO:0008015 | blood circulation | 8.00460589934371e-07 |
| GO:0003013 | circulatory system process | 8.00460589934371e-07 |
| GO:0008016 | regulation of heart contraction | 1.87474120082947e-06 |
| GO:0015629 | actin cytoskeleton | 5.58798492625664e-05 |
| GO:0007507 | heart development | 0.000149194663807349 |
| GO:0006810 | transport | 0.00023249115811724 |
| GO:0030016 | myofibril | 0.000233028500654032 |
| GO:0002026 | regulation of the force of heart contraction | 0.000233028500654032 |
| GO:0005737 | cytoplasm | 0.000233028500654032 |
| GO:0043292 | contractile fiber | 0.000233028500654032 |
| GO:0006811 | ion transport | 0.000233028500654032 |
| GO:0006941 | striated muscle contraction | 0.000233028500654032 |
| GO:0051234 | establishment of localization | 0.000350459826314133 |
| GO:0006812 | cation transport | 0.000350459826314133 |
| GO:0051179 | localization | 0.000513940083245913 |
| GO:0007517 | muscle development | 0.000515180871597746 |
| GO:0007275 | multicellular organismal development | 0.00074956042792845 |
| GO:0030017 | sarcomere | 0.0008411522096248 |
| GO:0044449 | contractile fiber part | 0.00104128268748163 |
| GO:0006816 | calcium ion transport | 0.00104128268748163 |
| GO:0003779 | actin binding | 0.00143393690865254 |
| GO:0030315 | T-tubule | 0.00189487480275978 |
| GO:0044429 | mitochondrial part | 0.00257313113952052 |
| GO:0030029 | actin filament-based process | 0.00268266449003746 |
| GO:0042383 | sarcolemma | 0.00299813715090446 |
| GO:0007010 | cytoskeleton organization and biogenesis | 0.00316249990497359 |
| GO:0030001 | metal ion transport | 0.00333798723030239 |
| GO:0051239 | regulation of multicellular organismal process | 0.00366158852718216 |
| GO:0015674 | di-, tri-valent inorganic cation transport | 0.00399504116334071 |
| GO:0044444 | cytoplasmic part | 0.00462022734316054 |
| GO:0055074 | calcium ion homeostasis | 0.0047109538347365 |
| GO:0022892 | substrate-specific transporter activity | 0.0047109538347365 |
| GO:0048731 | system development | 0.00532008251220623 |
| GO:0005886 | plasma membrane | 0.00532008251220623 |
| GO:0032502 | developmental process | 0.00542149498915157 |
| GO:0055065 | metal ion homeostasis | 0.00698688230142236 |
| GO:0031975 | envelope | 0.00767802064211943 |
| GO:0031967 | organelle envelope | 0.00767802064211943 |
| GO:0030036 | actin cytoskeleton organization and biogenesis | 0.00773130363001897 |
| GO:0008217 | regulation of blood pressure | 0.00843999871292809 |
| GO:0005740 | mitochondrial envelope | 0.0095486124423667 |
| GO:0032787 | monocarboxylic acid metabolic process | 0.0095486124423667 |
| GO:0015858 | nucleoside transport | 0.0095486124423667 |
| GO:0008053 | mitochondrial fusion | 0.0095486124423667 |
| GO:0008092 | cytoskeletal protein binding | 0.0105501906601928 |
| GO:0005741 | mitochondrial outer membrane | 0.0110513315443557 |
| GO:0043228 | non-membrane-bound organelle | 0.0117825612449189 |
| GO:0043232 | intracellular non-membrane-bound organelle | 0.0117825612449189 |
| GO:0019867 | outer membrane | 0.0119609250927756 |
| GO:0022857 | transmembrane transporter activity | 0.0129217654210232 |
| GO:0065008 | regulation of biological quality | 0.0134598061550316 |
| GO:0016909 | SAP kinase activity | 0.0137179722067018 |
| GO:0031968 | organelle outer membrane | 0.0145539192326834 |
| GO:0007632 | visual behavior | 0.0145539192326834 |
| GO:0008542 | visual learning | 0.0145539192326834 |
| GO:0048513 | organ development | 0.0149208476033745 |
| GO:0005739 | mitochondrion | 0.0152587431059341 |
| GO:0044255 | cellular lipid metabolic process | 0.0175422262649736 |
| GO:0045822 | negative regulation of heart contraction | 0.0175422262649736 |
| GO:0048284 | organelle fusion | 0.0175422262649736 |
| GO:0005337 | nucleoside transmembrane transporter activity | 0.0175422262649736 |
| GO:0005509 | calcium ion binding | 0.0180265685012877 |
| GO:0031966 | mitochondrial membrane | 0.0180265685012877 |
| GO:0006996 | organelle organization and biogenesis | 0.0185433915663281 |
| GO:0016459 | myosin complex | 0.0202089473164295 |
| GO:0044430 | cytoskeletal part | 0.0202089473164295 |
| GO:0022891 | substrate-specific transmembrane transporter activity | 0.0202089473164295 |
| GO:0055066 | di-, tri-valent inorganic cation homeostasis | 0.0206083150162924 |
| GO:0015932 | nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity | 0.0216439003786112 |
| GO:0006874 | cellular calcium ion homeostasis | 0.0218855038685561 |
| GO:0048856 | anatomical structure development | 0.022723554951081 |
| GO:0042593 | glucose homeostasis | 0.0230271862906976 |
| GO:0033500 | carbohydrate homeostasis | 0.0230271862906976 |
| GO:0048878 | chemical homeostasis | 0.024639843501122 |
| GO:0051146 | striated muscle cell differentiation | 0.024639843501122 |
| GO:0030018 | Z disc | 0.0269009990825435 |
| GO:0055080 | cation homeostasis | 0.0269597320508764 |
| GO:0006631 | fatty acid metabolic process | 0.0293309550517837 |
| GO:0006875 | cellular metal ion homeostasis | 0.0294704102782323 |
| GO:0007005 | mitochondrion organization and biogenesis | 0.0308016471077186 |
| GO:0005901 | caveola | 0.0308479412344508 |
| GO:0048738 | cardiac muscle development | 0.0308479412344508 |
| GO:0007512 | adult heart development | 0.0308479412344508 |
| GO:0046873 | metal ion transmembrane transporter activity | 0.0313575952518655 |
| GO:0006937 | regulation of muscle contraction | 0.0321774833985362 |
| GO:0050801 | ion homeostasis | 0.0323595563685176 |
| GO:0005244 | voltage-gated ion channel activity | 0.0326689386268836 |
| GO:0022832 | voltage-gated channel activity | 0.0326689386268836 |
| GO:0000267 | cell fraction | 0.0327673981371895 |
| GO:0031674 | I band | 0.0327673981371895 |
| GO:0045121 | lipid raft | 0.0327673981371895 |
| GO:0022843 | voltage-gated cation channel activity | 0.0327673981371895 |
| GO:0002027 | regulation of heart rate | 0.0343345324499743 |
| GO:0005246 | calcium channel regulator activity | 0.0343345324499743 |
| GO:0006629 | lipid metabolic process | 0.0366289343952199 |
| GO:0014706 | striated muscle development | 0.0388382010009254 |
| GO:0001976 | regulation of systemic arterial blood pressure by neurological process | 0.0402070325277714 |
| GO:0015075 | ion transmembrane transporter activity | 0.0424482973364429 |
| GO:0005624 | membrane fraction | 0.0427670422180957 |
| GO:0005515 | protein binding | 0.0427670422180957 |
| GO:0005261 | cation channel activity | 0.0427670422180957 |
| GO:0035265 | organ growth | 0.0454853305193667 |
| GO:0048646 | anatomical structure formation | 0.0473409537361205 |
| GO:0008324 | cation transmembrane transporter activity | 0.0478631726360756 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| primary circulatory organ | 2.95e-50 | 18 |
| heart | 2.95e-50 | 18 |
| primitive heart tube | 2.95e-50 | 18 |
| primary heart field | 2.95e-50 | 18 |
| anterior lateral plate mesoderm | 2.95e-50 | 18 |
| heart tube | 2.95e-50 | 18 |
| heart primordium | 2.95e-50 | 18 |
| cardiac mesoderm | 2.95e-50 | 18 |
| cardiogenic plate | 2.95e-50 | 18 |
| heart rudiment | 2.95e-50 | 18 |
| cardiovascular system | 8.63e-39 | 23 |
| circulatory system | 8.63e-39 | 23 |
| splanchnic layer of lateral plate mesoderm | 2.90e-26 | 33 |
| compound organ | 1.50e-19 | 43 |
| epithelial tube | 1.16e-17 | 47 |
| lateral plate mesoderm | 2.66e-08 | 87 |
| structure with developmental contribution from neural crest | 1.06e-07 | 92 |
| tube | 1.09e-07 | 114 |
| anatomical conduit | 5.54e-07 | 122 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0 |
| MA0004.1 | 0.000629943 |
| MA0006.1 | 3.40313e-07 |
| MA0007.1 | 0.269044 |
| MA0009.1 | 0.139516 |
| MA0014.1 | 0 |
| MA0017.1 | 1.63797 |
| MA0019.1 | 0.605292 |
| MA0024.1 | 0.00021933 |
| MA0025.1 | 0.1254 |
| MA0027.1 | 0.52099 |
| MA0028.1 | 1.79558e-13 |
| MA0029.1 | 0.268343 |
| MA0030.1 | 0.222161 |
| MA0031.1 | 0.700592 |
| MA0038.1 | 0.392239 |
| MA0040.1 | 0.231152 |
| MA0041.1 | 0.00160163 |
| MA0042.1 | 0.0568794 |
| MA0043.1 | 0.55478 |
| MA0046.1 | 0.107339 |
| MA0048.1 | 0.024783 |
| MA0050.1 | 0.0120729 |
| MA0051.1 | 0.0125207 |
| MA0052.1 | 22.2935 |
| MA0055.1 | 0.304438 |
| MA0056.1 | 0 |
| MA0057.1 | 1.4833e-07 |
| MA0058.1 | 0.00035066 |
| MA0059.1 | 0.0460513 |
| MA0060.1 | 1.06315e-10 |
| MA0061.1 | 6.48818e-06 |
| MA0063.1 | 0 |
| MA0066.1 | 1.28581 |
| MA0067.1 | 0.0279066 |
| MA0068.1 | 0.00508757 |
| MA0069.1 | 0.692226 |
| MA0070.1 | 0.227441 |
| MA0071.1 | 9.54657 |
| MA0072.1 | 1.6082 |
| MA0073.1 | 0 |
| MA0074.1 | 2.84858 |
| MA0076.1 | 2.16974e-15 |
| MA0077.1 | 1.78966 |
| MA0078.1 | 1.09155 |
| MA0081.1 | 0.116049 |
| MA0083.1 | 4.1413 |
| MA0084.1 | 0.348226 |
| MA0087.1 | 0.365588 |
| MA0088.1 | 0.000231894 |
| MA0089.1 | 0 |
| MA0090.1 | 6.65747 |
| MA0091.1 | 0.915994 |
| MA0092.1 | 2.78687 |
| MA0093.1 | 3.51633e-05 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.0264057 |
| MA0101.1 | 0.000290099 |
| MA0103.1 | 0.0967542 |
| MA0105.1 | 1.4355e-05 |
| MA0106.1 | 0.043564 |
| MA0107.1 | 0.000204905 |
| MA0108.2 | 0.921089 |
| MA0109.1 | 0 |
| MA0111.1 | 0.551571 |
| MA0113.1 | 1.50875 |
| MA0114.1 | 0.895141 |
| MA0115.1 | 1.72969 |
| MA0116.1 | 0.00275053 |
| MA0117.1 | 0.543711 |
| MA0119.1 | 1.37482 |
| MA0122.1 | 2.38133 |
| MA0124.1 | 0.218493 |
| MA0125.1 | 0.0291103 |
| MA0130.1 | 0 |
| MA0131.1 | 0.000791863 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.0344988 |
| MA0136.1 | 0.00504602 |
| MA0139.1 | 3.18299e-05 |
| MA0140.1 | 6.19102 |
| MA0141.1 | 16.8062 |
| MA0142.1 | 0.188631 |
| MA0143.1 | 0.601187 |
| MA0144.1 | 0.976876 |
| MA0145.1 | 0.0153946 |
| MA0146.1 | 2.33274e-10 |
| MA0147.1 | 0.000210043 |
| MA0148.1 | 1.93109 |
| MA0149.1 | 7.49926 |
| MA0062.2 | 0 |
| MA0035.2 | 12.2193 |
| MA0039.2 | 0 |
| MA0138.2 | 0.427937 |
| MA0002.2 | 0.121616 |
| MA0137.2 | 0.251089 |
| MA0104.2 | 1.93522e-05 |
| MA0047.2 | 1.44641 |
| MA0112.2 | 1.15088 |
| MA0065.2 | 1.40414 |
| MA0150.1 | 6.23726 |
| MA0151.1 | 0 |
| MA0152.1 | 1.59677 |
| MA0153.1 | 0.392392 |
| MA0154.1 | 1.1884 |
| MA0155.1 | 0.0549736 |
| MA0156.1 | 6.96435e-05 |
| MA0157.1 | 0.255874 |
| MA0158.1 | 0 |
| MA0159.1 | 4.76937 |
| MA0160.1 | 7.84936 |
| MA0161.1 | 0 |
| MA0162.1 | 0 |
| MA0163.1 | 0 |
| MA0164.1 | 0.154343 |
| MA0080.2 | 0.000346869 |
| MA0018.2 | 0.00279922 |
| MA0099.2 | 0.318451 |
| MA0079.2 | 0 |
| MA0102.2 | 0.0935531 |
| MA0258.1 | 5.95371 |
| MA0259.1 | 8.37243e-09 |
| MA0442.1 | 0 |
