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MCL coexpression mm9:976: Difference between revisions

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{{MCL_coexpression_mm9
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n=GO:0016861;intramolecular oxidoreductase activity, interconverting aldoses and ketoses;0.000128857921359924;19703,26384!GO:0019318;hexose metabolic process;0.000128857921359924;19703,26384,69976!GO:0005996;monosaccharide metabolic process;0.000128857921359924;19703,26384,69976!GO:0006041;glucosamine metabolic process;0.000185210849153496;19703,26384!GO:0006044;N-acetylglucosamine metabolic process;0.000185210849153496;19703,26384!GO:0006040;amino sugar metabolic process;0.000278238433679989;19703,26384!GO:0044262;cellular carbohydrate metabolic process;0.000329345436162799;19703,26384,69976!GO:0006066;alcohol metabolic process;0.000329345436162799;19703,26384,69976!GO:0016860;intramolecular oxidoreductase activity;0.000605618978561636;19703,26384!GO:0005975;carbohydrate metabolic process;0.000668734135780982;19703,26384,69976!GO:0008238;exopeptidase activity;0.00184444566190033;83768,19025!GO:0004186;carboxypeptidase C activity;0.00184444566190033;19025!GO:0046370;fructose biosynthetic process;0.00184444566190033;26384!GO:0050121;N-acylglucosamine 2-epimerase activity;0.00184444566190033;19703!GO:0006002;fructose 6-phosphate metabolic process;0.00184444566190033;26384!GO:0004476;mannose-6-phosphate isomerase activity;0.00307373925502968;19703!GO:0004342;glucosamine-6-phosphate deaminase activity;0.00307373925502968;26384!GO:0004335;galactokinase activity;0.00307373925502968;69976!GO:0016853;isomerase activity;0.00360238329815844;19703,26384!GO:0005764;lysosome;0.0040717293324298;83768,19025!GO:0000323;lytic vacuole;0.0040717293324298;83768,19025!GO:0005773;vacuole;0.00467577611898372;83768,19025!GO:0004185;serine carboxypeptidase activity;0.00467577611898372;19025!GO:0008236;serine-type peptidase activity;0.00467577611898372;83768,19025!GO:0017171;serine hydrolase activity;0.00467577611898372;83768,19025!GO:0006000;fructose metabolic process;0.00512121488680332;26384!GO:0006012;galactose metabolic process;0.00512121488680332;69976!GO:0046835;carbohydrate phosphorylation;0.00592532787518543;69976!GO:0016857;racemase and epimerase activity, acting on carbohydrates and derivatives;0.00667377588904681;19703!GO:0043170;macromolecule metabolic process;0.0071181114580042;19703,83768,26384,69976,19025!GO:0007340;acrosome reaction;0.00863731630838491;26384!GO:0006013;mannose metabolic process;0.00863731630838491;19703!GO:0009308;amine metabolic process;0.00950603627406468;19703,26384!GO:0016854;racemase and epimerase activity;0.00975294890479075;19703!GO:0006807;nitrogen compound metabolic process;0.010354764594616;19703,26384!GO:0044238;primary metabolic process;0.0120339471230969;19703,83768,26384,69976,19025!GO:0044237;cellular metabolic process;0.0120339471230969;19703,83768,26384,69976,19025!GO:0017156;calcium ion-dependent exocytosis;0.0145311266733661;26384!GO:0019239;deaminase activity;0.0148648313442383;26384!GO:0019319;hexose biosynthetic process;0.0158700377757918;26384!GO:0046165;alcohol biosynthetic 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|gostat_on_MCL_coexpression=GO:0016861;intramolecular oxidoreductase activity, interconverting aldoses and ketoses;0.000128857921359924;19703,26384!GO:0019318;hexose metabolic process;0.000128857921359924;19703,26384,69976!GO:0005996;monosaccharide metabolic process;0.000128857921359924;19703,26384,69976!GO:0006041;glucosamine metabolic process;0.000185210849153496;19703,26384!GO:0006044;N-acetylglucosamine metabolic process;0.000185210849153496;19703,26384!GO:0006040;amino sugar metabolic process;0.000278238433679989;19703,26384!GO:0044262;cellular carbohydrate metabolic process;0.000329345436162799;19703,26384,69976!GO:0006066;alcohol metabolic process;0.000329345436162799;19703,26384,69976!GO:0016860;intramolecular oxidoreductase activity;0.000605618978561636;19703,26384!GO:0005975;carbohydrate metabolic process;0.000668734135780982;19703,26384,69976!GO:0008238;exopeptidase activity;0.00184444566190033;83768,19025!GO:0004186;carboxypeptidase C activity;0.00184444566190033;19025!GO:0046370;fructose biosynthetic process;0.00184444566190033;26384!GO:0050121;N-acylglucosamine 2-epimerase activity;0.00184444566190033;19703!GO:0006002;fructose 6-phosphate metabolic process;0.00184444566190033;26384!GO:0004476;mannose-6-phosphate isomerase activity;0.00307373925502968;19703!GO:0004342;glucosamine-6-phosphate deaminase activity;0.00307373925502968;26384!GO:0004335;galactokinase activity;0.00307373925502968;69976!GO:0016853;isomerase activity;0.00360238329815844;19703,26384!GO:0005764;lysosome;0.0040717293324298;83768,19025!GO:0000323;lytic vacuole;0.0040717293324298;83768,19025!GO:0005773;vacuole;0.00467577611898372;83768,19025!GO:0004185;serine carboxypeptidase activity;0.00467577611898372;19025!GO:0008236;serine-type peptidase activity;0.00467577611898372;83768,19025!GO:0017171;serine hydrolase activity;0.00467577611898372;83768,19025!GO:0006000;fructose metabolic process;0.00512121488680332;26384!GO:0006012;galactose metabolic process;0.00512121488680332;69976!GO:0046835;carbohydrate phosphorylation;0.00592532787518543;69976!GO:0016857;racemase and epimerase activity, acting on carbohydrates and derivatives;0.00667377588904681;19703!GO:0043170;macromolecule metabolic process;0.0071181114580042;19703,83768,26384,69976,19025!GO:0007340;acrosome reaction;0.00863731630838491;26384!GO:0006013;mannose metabolic process;0.00863731630838491;19703!GO:0009308;amine metabolic process;0.00950603627406468;19703,26384!GO:0016854;racemase and epimerase activity;0.00975294890479075;19703!GO:0006807;nitrogen compound metabolic process;0.010354764594616;19703,26384!GO:0044238;primary metabolic process;0.0120339471230969;19703,83768,26384,69976,19025!GO:0044237;cellular metabolic process;0.0120339471230969;19703,83768,26384,69976,19025!GO:0017156;calcium ion-dependent exocytosis;0.0145311266733661;26384!GO:0019239;deaminase activity;0.0148648313442383;26384!GO:0019319;hexose biosynthetic process;0.0158700377757918;26384!GO:0046165;alcohol biosynthetic process;0.0164250103375253;26384!GO:0046364;monosaccharide biosynthetic process;0.0164250103375253;26384!GO:0019200;carbohydrate kinase activity;0.0186017631602618;69976!GO:0004177;aminopeptidase activity;0.0231050532608269;83768!GO:0006508;proteolysis;0.0231050532608269;83768,19025!GO:0007338;single fertilization;0.0243720217087801;26384!GO:0004180;carboxypeptidase activity;0.0243720217087801;19025!GO:0016787;hydrolase activity;0.0243720217087801;83768,26384,19025!GO:0008233;peptidase activity;0.0252410139007344;83768,19025!GO:0009566;fertilization;0.026971109984213;26384!GO:0016051;carbohydrate biosynthetic process;0.0424914869646335;26384!GO:0006887;exocytosis;0.044810011066312;26384!
}}

Latest revision as of 16:11, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr18:38498588..38498639,-p1@Gnpda1
Mm9::chr18:38498651..38498661,-p2@Gnpda1
Mm9::chr2:125691960..125692018,+p1@Galk2
Mm9::chr2:125692019..125692041,+p2@Galk2
Mm9::chr2:164659341..164659352,+p3@Ctsa
Mm9::chr2:25211831..25211838,-p2@Dpp7
Mm9::chr9:114310210..114310251,+p1@Tmppe
p2@Glb1
Mm9::chrX:71176090..71176162,-p1@Renbp


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016861intramolecular oxidoreductase activity, interconverting aldoses and ketoses0.000128857921359924
GO:0019318hexose metabolic process0.000128857921359924
GO:0005996monosaccharide metabolic process0.000128857921359924
GO:0006041glucosamine metabolic process0.000185210849153496
GO:0006044N-acetylglucosamine metabolic process0.000185210849153496
GO:0006040amino sugar metabolic process0.000278238433679989
GO:0044262cellular carbohydrate metabolic process0.000329345436162799
GO:0006066alcohol metabolic process0.000329345436162799
GO:0016860intramolecular oxidoreductase activity0.000605618978561636
GO:0005975carbohydrate metabolic process0.000668734135780982
GO:0008238exopeptidase activity0.00184444566190033
GO:0004186carboxypeptidase C activity0.00184444566190033
GO:0046370fructose biosynthetic process0.00184444566190033
GO:0050121N-acylglucosamine 2-epimerase activity0.00184444566190033
GO:0006002fructose 6-phosphate metabolic process0.00184444566190033
GO:0004476mannose-6-phosphate isomerase activity0.00307373925502968
GO:0004342glucosamine-6-phosphate deaminase activity0.00307373925502968
GO:0004335galactokinase activity0.00307373925502968
GO:0016853isomerase activity0.00360238329815844
GO:0005764lysosome0.0040717293324298
GO:0000323lytic vacuole0.0040717293324298
GO:0005773vacuole0.00467577611898372
GO:0004185serine carboxypeptidase activity0.00467577611898372
GO:0008236serine-type peptidase activity0.00467577611898372
GO:0017171serine hydrolase activity0.00467577611898372
GO:0006000fructose metabolic process0.00512121488680332
GO:0006012galactose metabolic process0.00512121488680332
GO:0046835carbohydrate phosphorylation0.00592532787518543
GO:0016857racemase and epimerase activity, acting on carbohydrates and derivatives0.00667377588904681
GO:0043170macromolecule metabolic process0.0071181114580042
GO:0007340acrosome reaction0.00863731630838491
GO:0006013mannose metabolic process0.00863731630838491
GO:0009308amine metabolic process0.00950603627406468
GO:0016854racemase and epimerase activity0.00975294890479075
GO:0006807nitrogen compound metabolic process0.010354764594616
GO:0044238primary metabolic process0.0120339471230969
GO:0044237cellular metabolic process0.0120339471230969
GO:0017156calcium ion-dependent exocytosis0.0145311266733661
GO:0019239deaminase activity0.0148648313442383
GO:0019319hexose biosynthetic process0.0158700377757918
GO:0046165alcohol biosynthetic process0.0164250103375253
GO:0046364monosaccharide biosynthetic process0.0164250103375253
GO:0019200carbohydrate kinase activity0.0186017631602618
GO:0004177aminopeptidase activity0.0231050532608269
GO:0006508proteolysis0.0231050532608269
GO:0007338single fertilization0.0243720217087801
GO:0004180carboxypeptidase activity0.0243720217087801
GO:0016787hydrolase activity0.0243720217087801
GO:0008233peptidase activity0.0252410139007344
GO:0009566fertilization0.026971109984213
GO:0016051carbohydrate biosynthetic process0.0424914869646335
GO:0006887exocytosis0.044810011066312



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.848341
MA0004.13.93894
MA0006.10.271714
MA0007.10.419994
MA0009.10.870101
MA0014.11.16295
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.769859
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.335404
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.11.64072
MA0056.10
MA0057.10.31126
MA0058.17.74363
MA0059.12.51175
MA0060.10.197678
MA0061.10.638933
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.0965831
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.11.1212e-05
MA0074.12.26329
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.980744
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.064239
MA0089.10
MA0090.10.401197
MA0091.11.13691
MA0092.10.401504
MA0093.17.12042
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.827743
MA0105.10.823589
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.11.06639
MA0113.10.598933
MA0114.11.18683
MA0115.10.969632
MA0116.10.747001
MA0117.10.937363
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.10.977634
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.246409
MA0146.10.636109
MA0147.11.24068
MA0148.10.450593
MA0149.10.367458
MA0062.20.426733
MA0035.20.524137
MA0039.20.812684
MA0138.20.675599
MA0002.20.513194
MA0137.20.32312
MA0104.21.64215
MA0047.20.576767
MA0112.20.527225
MA0065.20.247168
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.100744
MA0155.10.275377
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.0925951
MA0163.10.669601
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.21.60616
MA0079.20.118858
MA0102.21.59466
MA0258.10.60477
MA0259.10.227035
MA0442.10
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