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MCL coexpression mm9:1273: Difference between revisions

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{{MCL_coexpression_mm9
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0.0373501741982983,0.0730404042754446,0,0.0862838005840265,0,0,0,0,0,0,0,0,0,0,0,0,0,0.51947107288954,0.0826465040380816,0.464988884910168,0.472333824008762,0.525718357220373,0.552346168558927,0.664747945667008,0.435787611725567,0.511719335784993,0.478568928392717,0.531426154890509,0.525418923104807,0.59317613270515,0.529472509816973,0.445803526621278,0.606775972727315,0.505774492132087,0.548302816253453,0.563224006211606,0.402197278650986,0.530355313131398,0.500115130335887,0.537778209195429,0.44801421711693,0.593128928491147,0.509788266605557,0.41898031856205,0.50436171212853,0.510778907484639,0.483752028897937,0.609839337926682,0.61086768973395,0.766263836013545,0.704160740799184,0.698842160125315,1.01405577085298,0.470196221057323,0.30965439709354|gostat_on_MCL_coexpression=GO:0030019;tryptase activity;1.4407761922396e-06;17229,100503895!GO:0006508;proteolysis;2.30070746533166e-05;12873,17229,100503895,17228!GO:0008233;peptidase activity;2.30070746533166e-05;12873,17229,100503895,17228!GO:0004252;serine-type endopeptidase activity;3.37683257571474e-05;17229,100503895,17228!GO:0008236;serine-type peptidase activity;3.37683257571474e-05;17229,100503895,17228!GO:0017171;serine hydrolase activity;3.37683257571474e-05;17229,100503895,17228!GO:0004295;trypsin activity;9.55060518853957e-05;17229,100503895!GO:0004175;endopeptidase activity;0.000236121822834236;17229,100503895,17228!GO:0005615;extracellular space;0.000601401670937641;12873,17229,100503895,17228!GO:0016787;hydrolase activity;0.000612741725887718;12873,17229,100503895,17228!GO:0044421;extracellular region part;0.000621078313701449;12873,17229,100503895,17228!GO:0030271;chymase activity;0.000730473529465476;17228!GO:0044267;cellular protein metabolic process;0.00125734602011386;12873,17229,100503895,17228!GO:0044260;cellular macromolecule metabolic process;0.00125734602011386;12873,17229,100503895,17228!GO:0019538;protein metabolic process;0.00130092818928695;12873,17229,100503895,17228!GO:0004182;carboxypeptidase A activity;0.0142149937063408;12873!GO:0004181;metallocarboxypeptidase activity;0.0154320219846152;12873!GO:0043170;macromolecule metabolic process;0.0161077453899997;12873,17229,100503895,17228!GO:0004180;carboxypeptidase activity;0.019311576952437;12873!GO:0008235;metalloexopeptidase activity;0.0226911316367904;12873!GO:0044238;primary metabolic process;0.0226911316367904;12873,17229,100503895,17228!GO:0008201;heparin binding;0.0226911316367904;17229!GO:0044237;cellular metabolic process;0.0226911316367904;12873,17229,100503895,17228!GO:0005539;glycosaminoglycan binding;0.0268657992678773;17229!GO:0030247;polysaccharide binding;0.0282146244840345;17229!GO:0001871;pattern binding;0.0284598079152524;17229!GO:0008238;exopeptidase 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|gostat_on_MCL_coexpression=GO:0030019;tryptase activity;1.4407761922396e-06;17229,100503895!GO:0006508;proteolysis;2.30070746533166e-05;12873,17229,100503895,17228!GO:0008233;peptidase activity;2.30070746533166e-05;12873,17229,100503895,17228!GO:0004252;serine-type endopeptidase activity;3.37683257571474e-05;17229,100503895,17228!GO:0008236;serine-type peptidase activity;3.37683257571474e-05;17229,100503895,17228!GO:0017171;serine hydrolase activity;3.37683257571474e-05;17229,100503895,17228!GO:0004295;trypsin activity;9.55060518853957e-05;17229,100503895!GO:0004175;endopeptidase activity;0.000236121822834236;17229,100503895,17228!GO:0005615;extracellular space;0.000601401670937641;12873,17229,100503895,17228!GO:0016787;hydrolase activity;0.000612741725887718;12873,17229,100503895,17228!GO:0044421;extracellular region part;0.000621078313701449;12873,17229,100503895,17228!GO:0030271;chymase activity;0.000730473529465476;17228!GO:0044267;cellular protein metabolic process;0.00125734602011386;12873,17229,100503895,17228!GO:0044260;cellular macromolecule metabolic process;0.00125734602011386;12873,17229,100503895,17228!GO:0019538;protein metabolic process;0.00130092818928695;12873,17229,100503895,17228!GO:0004182;carboxypeptidase A activity;0.0142149937063408;12873!GO:0004181;metallocarboxypeptidase activity;0.0154320219846152;12873!GO:0043170;macromolecule metabolic process;0.0161077453899997;12873,17229,100503895,17228!GO:0004180;carboxypeptidase activity;0.019311576952437;12873!GO:0008235;metalloexopeptidase activity;0.0226911316367904;12873!GO:0044238;primary metabolic process;0.0226911316367904;12873,17229,100503895,17228!GO:0008201;heparin binding;0.0226911316367904;17229!GO:0044237;cellular metabolic process;0.0226911316367904;12873,17229,100503895,17228!GO:0005539;glycosaminoglycan binding;0.0268657992678773;17229!GO:0030247;polysaccharide binding;0.0282146244840345;17229!GO:0001871;pattern binding;0.0284598079152524;17229!GO:0008238;exopeptidase activity;0.030285097985417;12873!
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|ontology_enrichment_uberon=
|tfbs_overrepresentation_for_novel_motifs=0.491922,0.0600685,0.464605,0.535892,0.346849,1.35778,0.645383,0.247459,0.257202,0.0835344,0.599767,0.632897,0.247704,0.6581,0.364314,0,0.856992,1.61113,0.232269,0.442204,0.426133,0.35122,0.657163,0.345236,1.19059,0.686615,0.223823,0.572827,0.394364,0.181062,0.558142,0.960397,0.892985,0.204204,0.364821,0.951637,0.326478,0.629145,0.303703,0.27383,0.342638,0.56353,0.327433,0.366415,0.161543,0.524258,0.77511,0.589246,0.594982,0.397446,0.839084,0.714419,0.174327,1.10437,1.12205,0.66551,0.406788,0.619643,0.614918,0.663395,0.939962,0.724164,0.269393,0.827522,0.677043,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,0.253541,0.11437,1.156,0.208101,0.57254,1.11463,0.763395,0.922432,0.430551,0.254777,0.874787,0.722675,0.240896,1.03903,0.0539203,11.0987,0.181203,0.780154,1.77427,1.33021,1.04409,0.973447,0.35304,0.2995,0.281222,0.244935,0.976308,0.775372,0.160254,0.871473,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,0.585058,0.435642,0.428007,0.484547,1.0885,0.431734,0.605144,1.33732,1.61894,0.0704207,0.53982,0.858327,0.322606,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,0.356163,1.06946,0.52828,1.2285,0.679647,1.35909,0.106956,0.500709,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,0.971067,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,0.183562,0.0987301,1.10596,0.287383,0.678689,1.18867,0.71546,1.74506,0.48935,0.500417,1.31911,1.03816,0.926663,0.482185,0.82857,0.671017,1.56426,0.63125,0.0323861
|tfbs_overrepresentation_jaspar=MA0003.1;0.04894,MA0004.1;0.536396,MA0006.1;0.359699,MA0007.1;0.52077,MA0009.1;0.987341,MA0014.1;0.0315641,MA0017.1;1.7816,MA0019.1;0.800946,MA0024.1;0.942716,MA0025.1;1.22395,MA0027.1;2.64231,MA0028.1;0.370592,MA0029.1;0.920529,MA0030.1;0.927235,MA0031.1;0.890871,MA0038.1;0.686534,MA0040.1;1.00009,MA0041.1;0.457338,MA0042.1;0.443591,MA0043.1;1.08567,MA0046.1;1.02391,MA0048.1;0.161427,MA0050.1;0.57678,MA0051.1;0.695779,MA0052.1;1.00829,MA0055.1;0.212634,MA0056.1;0,MA0057.1;0.149949,MA0058.1;0.436487,MA0059.1;0.449345,MA0060.1;0.275911,MA0061.1;0.307097,MA0063.1;0,MA0066.1;0.675169,MA0067.1;1.33603,MA0068.1;0.153907,MA0069.1;1.00864,MA0070.1;0.998765,MA0071.1;0.575909,MA0072.1;0.990133,MA0073.1;5.00847,MA0074.1;0.638014,MA0076.1;0.407465,MA0077.1;0.968053,MA0078.1;0.729877,MA0081.1;0.473489,MA0083.1;1.08487,MA0084.1;1.66561,MA0087.1;1.04109,MA0088.1;0.111145,MA0089.1;0,MA0090.1;0.500693,MA0091.1;0.55008,MA0092.1;0.501022,MA0093.1;0.379257,MA0095.1;0,MA0098.1;0,MA0100.1;0.626021,MA0101.1;0.458688,MA0103.1;0.398766,MA0105.1;0.199622,MA0106.1;0.737893,MA0107.1;0.392331,MA0108.2;0.824407,MA0109.1;0,MA0111.1;0.515457,MA0113.1;0.708789,MA0114.1;1.49046,MA0115.1;1.08851,MA0116.1;0.359483,MA0117.1;1.05576,MA0119.1;0.459301,MA0122.1;1.07591,MA0124.1;1.28237,MA0125.1;1.20757,MA0130.1;0,MA0131.1;0.796279,MA0132.1;0,MA0133.1;0,MA0135.1;1.1226,MA0136.1;0.658622,MA0139.1;0.243463,MA0140.1;0.625902,MA0141.1;0.419361,MA0142.1;0.876028,MA0143.1;0.725672,MA0144.1;0.307873,MA0145.1;0.119202,MA0146.1;0.0392287,MA0147.1;0.320675,MA0148.1;0.553294,MA0149.1;0.464445,MA0062.2;0.204999,MA0035.2;0.630778,MA0039.2;0.0271858,MA0138.2;0.788113,MA0002.2;0.689262,MA0137.2;0.416331,MA0104.2;0.261255,MA0047.2;0.685741,MA0112.2;0.119197,MA0065.2;0.763394,MA0150.1;1.29346,MA0151.1;0,MA0152.1;0.685852,MA0153.1;1.13945,MA0154.1;0.159217,MA0155.1;0.132921,MA0156.1;0.406559,MA0157.1;0.843181,MA0158.1;0,MA0159.1;1.58527,MA0160.1;1.36931,MA0161.1;0,MA0162.1;0.0465447,MA0163.1;0.0423021,MA0164.1;3.89126,MA0080.2;0.393257,MA0018.2;0.669032,MA0099.2;0.781628,MA0079.2;0.000341844,MA0102.2;1.7182,MA0258.1;0.290587,MA0259.1;0.309517,MA0442.1;0
}}

Latest revision as of 16:40, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:109797621..109797632,+p1@ENSMUST00000149226
Mm9::chr14:56563373..56563406,-p@chr14:56563373..56563406
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Mm9::chr17:25482504..25482508,-p1@Tpsab1
Mm9::chr17:25503225..25503257,+p2@Tpsb2
Mm9::chr17:25503260..25503273,+p1@Tpsb2
Mm9::chr3:20142072..20142086,-p1@Cpa3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030019tryptase activity1.4407761922396e-06
GO:0006508proteolysis2.30070746533166e-05
GO:0008233peptidase activity2.30070746533166e-05
GO:0004252serine-type endopeptidase activity3.37683257571474e-05
GO:0008236serine-type peptidase activity3.37683257571474e-05
GO:0017171serine hydrolase activity3.37683257571474e-05
GO:0004295trypsin activity9.55060518853957e-05
GO:0004175endopeptidase activity0.000236121822834236
GO:0005615extracellular space0.000601401670937641
GO:0016787hydrolase activity0.000612741725887718
GO:0044421extracellular region part0.000621078313701449
GO:0030271chymase activity0.000730473529465476
GO:0044267cellular protein metabolic process0.00125734602011386
GO:0044260cellular macromolecule metabolic process0.00125734602011386
GO:0019538protein metabolic process0.00130092818928695
GO:0004182carboxypeptidase A activity0.0142149937063408
GO:0004181metallocarboxypeptidase activity0.0154320219846152
GO:0043170macromolecule metabolic process0.0161077453899997
GO:0004180carboxypeptidase activity0.019311576952437
GO:0008235metalloexopeptidase activity0.0226911316367904
GO:0044238primary metabolic process0.0226911316367904
GO:0008201heparin binding0.0226911316367904
GO:0044237cellular metabolic process0.0226911316367904
GO:0005539glycosaminoglycan binding0.0268657992678773
GO:0030247polysaccharide binding0.0282146244840345
GO:0001871pattern binding0.0284598079152524
GO:0008238exopeptidase activity0.030285097985417



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.04894
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.11.7816
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.161427
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.10.212634
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.15.00847
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.111145
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.11.49046
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.0392287
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.20.0271858
MA0138.20.788113
MA0002.20.689262
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.119197
MA0065.20.763394
MA0150.11.29346
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.159217
MA0155.10.132921
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.11.58527
MA0160.11.36931
MA0161.10
MA0162.10.0465447
MA0163.10.0423021
MA0164.13.89126
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.20.000341844
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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