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MCL coexpression mm9:1323: Difference between revisions

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{{MCL_coexpression_mm9
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regulation of striated muscle development;0.0427163126445435;22160!GO:0035115;embryonic forelimb morphogenesis;0.0427163126445435;22160!GO:0016202;regulation of striated muscle development;0.0427163126445435;22160!GO:0035136;forelimb morphogenesis;0.0427163126445435;22160!GO:0035137;hindlimb morphogenesis;0.0449155998709496;22160!GO:0001843;neural tube closure;0.0449155998709496;22160!GO:0014020;primary neural tube formation;0.0449155998709496;22160!GO:0001841;neural tube formation;0.0449155998709496;22160!GO:0001839;neural plate morphogenesis;0.0449155998709496;22160!GO:0001764;neuron migration;0.0449155998709496;22160!GO:0001840;neural plate development;0.0449155998709496;22160!GO:0001838;embryonic epithelial tube formation;0.0449155998709496;22160!GO:0030326;embryonic limb morphogenesis;0.0449155998709496;22160!GO:0035113;embryonic appendage morphogenesis;0.0449155998709496;22160!GO:0021915;neural tube development;0.0449155998709496;22160!GO:0016331;morphogenesis of embryonic epithelium;0.0449155998709496;22160!GO:0035107;appendage morphogenesis;0.0449155998709496;22160!GO:0035108;limb morphogenesis;0.0449155998709496;22160!GO:0048736;appendage development;0.0449155998709496;22160!GO:0060173;limb development;0.0449155998709496;22160!GO:0045596;negative regulation of cell differentiation;0.0460180485381822;22160!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=|tfbs_overrepresentation_for_novel_motifs=0.491922,1.73744,0.464605,0.535892,0.346849,0.550971,0.645383,0.247459,0.257202,0.0835344,0.599767,0.632897,4.57206,0.6581,0.364314,0,0.856992,0.338549,1.22315,0.442204,1.09054,1.17476,1.58083,0.345236,1.19059,0.686615,0.223823,0.572827,1.80527,1.61954,2.35193,0.960397,0.336199,0.589948,0.364821,0.335531,0.326478,0.629145,0.303703,0.752287,0.342638,0.56353,2.23691,0.366415,1.9448,0.524258,0.77511,1.43855,1.48928,0.397446,0.839084,0.714419,0.174327,1.10437,1.12205,0.66551,0.406788,0.619643,0.21472,0.663395,0.939962,1.72013,0.269393,1.93338,2.73492,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,1.30328,0.740068,1.156,0.599223,0.19692,0.204132,0.763395,0.922432,0.430551,0.254777,0.874787,0.722675,1.25583,1.03903,1.6478,0.0610418,0.181203,0.780154,1.77427,1.33021,1.04409,0.973447,0.35304,1.47187,0.281222,1.27104,0.976308,0.775372,0.160254,0.326561,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,0.585058,0.435642,1.09461,0.484547,1.0885,0.431734,0.605144,1.33732,0.340765,0.902522,0.53982,0.858327,0.322606,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,0.356163,1.06946,0.52828,1.2285,0.679647,1.35909,0.106956,0.500709,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,0.971067,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,0.540361,0.667976,1.10596,0.287383,0.678689,1.18867,0.71546,0.983048,0.48935,2.16235,1.31911,1.03816,0.926663,0.482185,0.82857,0.671017,0.325308,0.63125,7.66449|tfbs_overrepresentation_jaspar=MA0003.1;4.94208,MA0004.1;0.536396,MA0006.1;0.359699,MA0007.1;0.52077,MA0009.1;0.987341,MA0014.1;4.64288,MA0017.1;0.387481,MA0019.1;0.800946,MA0024.1;0.942716,MA0025.1;1.22395,MA0027.1;2.64231,MA0028.1;0.370592,MA0029.1;0.920529,MA0030.1;0.927235,MA0031.1;0.890871,MA0038.1;0.686534,MA0040.1;1.00009,MA0041.1;0.457338,MA0042.1;0.443591,MA0043.1;1.08567,MA0046.1;1.02391,MA0048.1;0.486223,MA0050.1;0.57678,MA0051.1;0.695779,MA0052.1;1.00829,MA0055.1;4.94171,MA0056.1;0,MA0057.1;1.43735,MA0058.1;0.436487,MA0059.1;0.449345,MA0060.1;0.275911,MA0061.1;0.307097,MA0063.1;0,MA0066.1;0.675169,MA0067.1;1.33603,MA0068.1;0.467569,MA0069.1;1.00864,MA0070.1;0.998765,MA0071.1;0.575909,MA0072.1;0.990133,MA0073.1;9.97809,MA0074.1;0.638014,MA0076.1;0.407465,MA0077.1;0.968053,MA0078.1;0.729877,MA0081.1;0.473489,MA0083.1;1.08487,MA0084.1;1.66561,MA0087.1;1.04109,MA0088.1;1.19273,MA0089.1;0,MA0090.1;0.500693,MA0091.1;0.55008,MA0092.1;0.501022,MA0093.1;0.379257,MA0095.1;0,MA0098.1;0,MA0100.1;0.626021,MA0101.1;0.458688,MA0103.1;0.398766,MA0105.1;0.199622,MA0106.1;0.737893,MA0107.1;0.392331,MA0108.2;0.824407,MA0109.1;0,MA0111.1;0.515457,MA0113.1;0.708789,MA0114.1;0.304661,MA0115.1;1.08851,MA0116.1;0.944657,MA0117.1;1.05576,MA0119.1;2.02544,MA0122.1;1.07591,MA0124.1;1.28237,MA0125.1;1.20757,MA0130.1;0,MA0131.1;0.796279,MA0132.1;0,MA0133.1;0,MA0135.1;1.1226,MA0136.1;0.658622,MA0139.1;1.2655,MA0140.1;0.625902,MA0141.1;1.89066,MA0142.1;0.876028,MA0143.1;0.725672,MA0144.1;0.307873,MA0145.1;1.814,MA0146.1;2.42438,MA0147.1;0.320675,MA0148.1;0.553294,MA0149.1;0.464445,MA0062.2;0.204999,MA0035.2;0.630778,MA0039.2;1.76222,MA0138.2;1.85228,MA0002.2;0.246463,MA0137.2;0.416331,MA0104.2;0.261255,MA0047.2;0.685741,MA0112.2;0.37938,MA0065.2;3.92169,MA0150.1;0.520653,MA0151.1;0,MA0152.1;0.685852,MA0153.1;1.13945,MA0154.1;2.13869,MA0155.1;6.756,MA0156.1;0.406559,MA0157.1;0.843181,MA0158.1;0,MA0159.1;0.331229,MA0160.1;0.556423,MA0161.1;0,MA0162.1;1.08528,MA0163.1;4.40286,MA0164.1;0.658997,MA0080.2;0.393257,MA0018.2;0.669032,MA0099.2;0.781628,MA0079.2;10.8763,MA0102.2;1.7182,MA0258.1;0.290587,MA0259.1;0.309517,MA0442.1;0}}
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|gostat_on_MCL_coexpression=GO:0045843;negative regulation of striated muscle development;0.0427163126445435;22160!GO:0035115;embryonic forelimb morphogenesis;0.0427163126445435;22160!GO:0016202;regulation of striated muscle development;0.0427163126445435;22160!GO:0035136;forelimb morphogenesis;0.0427163126445435;22160!GO:0035137;hindlimb morphogenesis;0.0449155998709496;22160!GO:0001843;neural tube closure;0.0449155998709496;22160!GO:0014020;primary neural tube formation;0.0449155998709496;22160!GO:0001841;neural tube formation;0.0449155998709496;22160!GO:0001839;neural plate morphogenesis;0.0449155998709496;22160!GO:0001764;neuron migration;0.0449155998709496;22160!GO:0001840;neural plate development;0.0449155998709496;22160!GO:0001838;embryonic epithelial tube formation;0.0449155998709496;22160!GO:0030326;embryonic limb morphogenesis;0.0449155998709496;22160!GO:0035113;embryonic appendage morphogenesis;0.0449155998709496;22160!GO:0021915;neural tube development;0.0449155998709496;22160!GO:0016331;morphogenesis of embryonic epithelium;0.0449155998709496;22160!GO:0035107;appendage morphogenesis;0.0449155998709496;22160!GO:0035108;limb morphogenesis;0.0449155998709496;22160!GO:0048736;appendage development;0.0449155998709496;22160!GO:0060173;limb development;0.0449155998709496;22160!GO:0045596;negative regulation of cell differentiation;0.0460180485381822;22160!
}}

Latest revision as of 16:45, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr12:34642682..34642753,+p2@Twist1
Mm9::chr19:5068077..5068085,+p3@Cd248
Mm9::chr19:5068087..5068098,+p2@Cd248
Mm9::chr19:5068101..5068115,+p1@Cd248
Mm9::chr19:5068117..5068122,+p4@Cd248
Mm9::chr19:5069431..5069446,+p@chr19:5069431..5069446
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045843negative regulation of striated muscle development0.0427163126445435
GO:0035115embryonic forelimb morphogenesis0.0427163126445435
GO:0016202regulation of striated muscle development0.0427163126445435
GO:0035136forelimb morphogenesis0.0427163126445435
GO:0035137hindlimb morphogenesis0.0449155998709496
GO:0001843neural tube closure0.0449155998709496
GO:0014020primary neural tube formation0.0449155998709496
GO:0001841neural tube formation0.0449155998709496
GO:0001839neural plate morphogenesis0.0449155998709496
GO:0001764neuron migration0.0449155998709496
GO:0001840neural plate development0.0449155998709496
GO:0001838embryonic epithelial tube formation0.0449155998709496
GO:0030326embryonic limb morphogenesis0.0449155998709496
GO:0035113embryonic appendage morphogenesis0.0449155998709496
GO:0021915neural tube development0.0449155998709496
GO:0016331morphogenesis of embryonic epithelium0.0449155998709496
GO:0035107appendage morphogenesis0.0449155998709496
GO:0035108limb morphogenesis0.0449155998709496
GO:0048736appendage development0.0449155998709496
GO:0060173limb development0.0449155998709496
GO:0045596negative regulation of cell differentiation0.0460180485381822



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.14.94208
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.14.64288
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.486223
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.14.94171
MA0056.10
MA0057.11.43735
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.467569
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.19.97809
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.11.19273
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.944657
MA0117.11.05576
MA0119.12.02544
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.11.2655
MA0140.10.625902
MA0141.11.89066
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.11.814
MA0146.12.42438
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.21.76222
MA0138.21.85228
MA0002.20.246463
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.37938
MA0065.23.92169
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.12.13869
MA0155.16.756
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.11.08528
MA0163.14.40286
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.210.8763
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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