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MCL coexpression mm9:2533: Difference between revisions

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{{MCL_coexpression_mm9
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filament sliding;0.00635477151876984;17904!GO:0016461;unconventional myosin complex;0.00635477151876984;17904!GO:0033275;actin-myosin filament sliding;0.00635477151876984;17904!GO:0007010;cytoskeleton organization and biogenesis;0.00867692153529255;11475,17904!GO:0008307;structural constituent of muscle;0.0101662416797126;17904!GO:0030048;actin filament-based movement;0.0158817059832277;17904!GO:0005856;cytoskeleton;0.0183301361737783;11475,17904!GO:0006996;organelle organization and biogenesis;0.0262599155568277;11475,17904!GO:0016459;myosin complex;0.0338518410700433;17904!GO:0043232;intracellular non-membrane-bound organelle;0.0338518410700433;11475,17904!GO:0043228;non-membrane-bound organelle;0.0338518410700433;11475,17904!GO:0003012;muscle system process;0.0388216747284698;17904!GO:0006936;muscle contraction;0.0388216747284698;17904!GO:0005200;structural constituent of cytoskeleton;0.0388216747284698;11475!GO:0007519;skeletal muscle development;0.0388216747284698;17904!GO:0030705;cytoskeleton-dependent intracellular transport;0.0388216747284698;17904!GO:0014706;striated muscle development;0.0454561548028362;17904!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0004535!2.35e-08!23;UBERON:0001009!2.35e-08!23;UBERON:0004872!1.42e-07!33|tfbs_overrepresentation_for_novel_motifs=0.752782,0.193418,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,0.66329,0.870507,0.906098,0.467629,0.933025,0.608226,0,1.14208,0.578045,0.448066,0.328717,0.679146,0.275782,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,0.380786,0.825437,1.24901,0.575271,1.05917,0.608816,0.872889,0.563758,0.902078,0.536514,0.50014,0.582863,0.831295,0.261619,0.610669,0.922882,0.788421,1.05665,0.859154,0.235354,0.646474,1.12346,0.99279,0.371606,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,0.494668,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,0.284975,1.44925,0.416814,0.402065,0.411601,1.04436,1.20986,0.684144,0.476502,1.16055,1.00151,0.459035,1.32978,0.181575,0.195254,0.99201,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,0.531443,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,1.63982,0.876299,1.63327,0.580657,0.212464,0.805461,1.14346,0.559153,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,0.598722,1.36093,0.792832,1.52297,0.955954,1.65529,0.751419,1.79943,0.832891,1.60513,2.44352,2.04137,1.55966,2.24236,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,0.38417,0.260379,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,2.17757,0.562367,0.904334,0.135528|tfbs_overrepresentation_jaspar=MA0003.1;0.0699972,MA0004.1;0.801718,MA0006.1;0.60285,MA0007.1;0.784593,MA0009.1;1.27673,MA0014.1;0.133574,MA0017.1;0.635031,MA0019.1;1.08369,MA0024.1;1.23079,MA0025.1;1.51835,MA0027.1;2.9431,MA0028.1;0.61552,MA0029.1;1.20789,MA0030.1;1.21482,MA0031.1;1.17722,MA0038.1;0.963265,MA0040.1;1.28983,MA0041.1;0.714279,MA0042.1;0.69885,MA0043.1;1.3775,MA0046.1;1.31428,MA0048.1;0.932001,MA0050.1;0.845669,MA0051.1;0.973068,MA0052.1;1.29825,MA0055.1;0.190475,MA0056.1;0,MA0057.1;0.896032,MA0058.1;0.690848,MA0059.1;0.705317,MA0060.1;0.502699,MA0061.1;0.5406,MA0063.1;0,MA0066.1;0.951196,MA0067.1;1.63197,MA0068.1;0.343188,MA0069.1;1.29861,MA0070.1;1.28847,MA0071.1;0.844726,MA0072.1;1.2796,MA0073.1;0.0430758,MA0074.1;0.911576,MA0076.1;0.657929,MA0077.1;1.2569,MA0078.1;1.0091,MA0081.1;0.732313,MA0083.1;6.86469,MA0084.1;1.96428,MA0087.1;1.33189,MA0088.1;0.766354,MA0089.1;0,MA0090.1;3.00547,MA0091.1;0.816659,MA0092.1;0.762845,MA0093.1;0.62555,MA0095.1;0,MA0098.1;0,MA0100.1;0.89873,MA0101.1;0.71579,MA0103.1;0.647985,MA0105.1;0.405648,MA0106.1;1.01755,MA0107.1;0.640607,MA0108.2;1.10817,MA0109.1;0,MA0111.1;0.778753,MA0113.1;0.986839,MA0114.1;1.3296,MA0115.1;1.38041,MA0116.1;0.602598,MA0117.1;1.34691,MA0119.1;0.716476,MA0122.1;1.36752,MA0124.1;1.57762,MA0125.1;1.5017,MA0130.1;0,MA0131.1;1.07881,MA0132.1;0,MA0133.1;0,MA0135.1;1.4152,MA0136.1;2.15063,MA0139.1;1.16863,MA0140.1;0.898603,MA0141.1;0.671467,MA0142.1;1.16183,MA0143.1;1.00467,MA0144.1;0.541532,MA0145.1;0.794492,MA0146.1;0.151124,MA0147.1;0.556853,MA0148.1;1.91825,MA0149.1;0.722227,MA0062.2;0.412742,MA0035.2;0.903829,MA0039.2;0.181475,MA0138.2;1.07027,MA0002.2;1.17677,MA0137.2;0.668025,MA0104.2;0.48458,MA0047.2;2.20949,MA0112.2;0.29236,MA0065.2;0.79573,MA0150.1;0.784464,MA0151.1;0,MA0152.1;0.962542,MA0153.1;1.43238,MA0154.1;0.35067,MA0155.1;0.312898,MA0156.1;0.656895,MA0157.1;1.12772,MA0158.1;0,MA0159.1;1.39671,MA0160.1;0.823568,MA0161.1;0,MA0162.1;0.964824,MA0163.1;0.157796,MA0164.1;2.15144,MA0080.2;1.54848,MA0018.2;0.944669,MA0099.2;1.06348,MA0079.2;0.00937321,MA0102.2;2.01714,MA0258.1;0.520639,MA0259.1;0.543506,MA0442.1;0}}
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|gostat_on_MCL_coexpression=GO:0030049;muscle filament sliding;0.00635477151876984;17904!GO:0016461;unconventional myosin complex;0.00635477151876984;17904!GO:0033275;actin-myosin filament sliding;0.00635477151876984;17904!GO:0007010;cytoskeleton organization and biogenesis;0.00867692153529255;11475,17904!GO:0008307;structural constituent of muscle;0.0101662416797126;17904!GO:0030048;actin filament-based movement;0.0158817059832277;17904!GO:0005856;cytoskeleton;0.0183301361737783;11475,17904!GO:0006996;organelle organization and biogenesis;0.0262599155568277;11475,17904!GO:0016459;myosin complex;0.0338518410700433;17904!GO:0043232;intracellular non-membrane-bound organelle;0.0338518410700433;11475,17904!GO:0043228;non-membrane-bound organelle;0.0338518410700433;11475,17904!GO:0003012;muscle system process;0.0388216747284698;17904!GO:0006936;muscle contraction;0.0388216747284698;17904!GO:0005200;structural constituent of cytoskeleton;0.0388216747284698;11475!GO:0007519;skeletal muscle development;0.0388216747284698;17904!GO:0030705;cytoskeleton-dependent intracellular transport;0.0388216747284698;17904!GO:0014706;striated muscle development;0.0454561548028362;17904!
}}

Latest revision as of 18:41, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:127930011..127930023,-p4@Myl6
Mm9::chr10:127930027..127930090,-p2@Myl6
Mm9::chr19:34329815..34329832,-p1@Acta2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030049muscle filament sliding0.00635477151876984
GO:0016461unconventional myosin complex0.00635477151876984
GO:0033275actin-myosin filament sliding0.00635477151876984
GO:0007010cytoskeleton organization and biogenesis0.00867692153529255
GO:0008307structural constituent of muscle0.0101662416797126
GO:0030048actin filament-based movement0.0158817059832277
GO:0005856cytoskeleton0.0183301361737783
GO:0006996organelle organization and biogenesis0.0262599155568277
GO:0016459myosin complex0.0338518410700433
GO:0043232intracellular non-membrane-bound organelle0.0338518410700433
GO:0043228non-membrane-bound organelle0.0338518410700433
GO:0003012muscle system process0.0388216747284698
GO:0006936muscle contraction0.0388216747284698
GO:0005200structural constituent of cytoskeleton0.0388216747284698
GO:0007519skeletal muscle development0.0388216747284698
GO:0030705cytoskeleton-dependent intracellular transport0.0388216747284698
GO:0014706striated muscle development0.0454561548028362



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
cardiovascular system2.35e-0823
circulatory system2.35e-0823
splanchnic layer of lateral plate mesoderm1.42e-0733


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0699972
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.10.133574
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.932001
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.896032
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.0430758
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.16.86469
MA0084.11.96428
MA0087.11.33189
MA0088.10.766354
MA0089.10
MA0090.13.00547
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.11.3296
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.12.15063
MA0139.11.16863
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.794492
MA0146.10.151124
MA0147.10.556853
MA0148.11.91825
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.181475
MA0138.21.07027
MA0002.21.17677
MA0137.20.668025
MA0104.20.48458
MA0047.22.20949
MA0112.20.29236
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.11.39671
MA0160.10.823568
MA0161.10
MA0162.10.964824
MA0163.10.157796
MA0164.12.15144
MA0080.21.54848
MA0018.20.944669
MA0099.21.06348
MA0079.20.00937321
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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