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{{CL
{{CL
|id=CL:0000682
|alt_id=
|name=M cell
|namespace=cell
|def="An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes." [GOC:jb, GOC:tfm]
|xref=BTO:0003600;;FMA:62929
|is_a=CL:0000066;;CL:0000473;;CL:0000627;;CL:0002371
|synonym="M-cell" EXACT [];;"microfold cell" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes." [GOC:jb, GOC:tfm]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000682
|is_a=CL:0000473 ;;CL:0000627 ;;CL:0002251
|is_obsolete=
|located_in=
|located_in=
|part_of=
|name=M cell
|namespace=cell
|obo_creation_date=
|part_of=UBERON:0003929
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="M-cell" EXACT [];;"microfold cell" EXACT []
|union_of=
|xref=BTO:0003600;;FMA:62929
}}
}}

Revision as of 10:20, 12 September 2014

Name:M cell
Namespace:cell
Definition:"An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes." [GOC:jb, GOC:tfm]
Xrefs:
links:

BTO:0003600

FMA:62929
Synonyms: "M-cell" EXACT []
"microfold cell" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000473(defensive cell),CL:0000627(transporting cell),CL:0002251(epithelial cell of alimentary canal)
part_of:UBERON:0003929(gut epithelium)



Children


derives from:FF:0011159 (mouse GP2-positive M cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000682 (M cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
7.35e-53FFCP PHASE2:Mm9::chr6:3437479..3437484,-#_5ffdfa673df7469cf842c6cb2d2ce0f6p@chr6:3437479..3437484, -
7.35e-53FFCP PHASE1:Mm9::chr6:3437479..3437484,-#_5ffdfa673df7469cf842c6cb2d2ce0f6p@chr6:3437479..3437484, -
1.65e-52FFCP PHASE1:Mm9::chr1:72247892..72247896,-#_db4436cf498678433d648a809f600cdfp@chr1:72247892..72247896, -
1.65e-52FFCP PHASE2:Mm9::chr1:72247892..72247896,-#_db4436cf498678433d648a809f600cdfp@chr1:72247892..72247896, -
1.65e-52FFCP PHASE2:Mm9::chr8:124945700..124945703,+#_db4436cf498678433d648a809f600cdfp1@Il17c
1.65e-52FFCP PHASE1:Mm9::chr8:124945700..124945703,+#_db4436cf498678433d648a809f600cdfp1@Il17c
4.58e-44FFCP PHASE1:Mm9::chr7:38968769..38968776,+#_0e0663c21e28afed52683e7a8f44967dp10@1600014C10Rik
4.58e-44FFCP PHASE2:Mm9::chr7:38968769..38968776,+#_0e0663c21e28afed52683e7a8f44967dp10@1600014C10Rik
6.41e-44FFCP PHASE1:Mm9::chr4:104940057..104940067,+#_a49a87d81218442ff6b28e4e4120b245p@chr4:104940057..104940067, +
6.41e-44FFCP PHASE2:Mm9::chr4:104940057..104940067,+#_a49a87d81218442ff6b28e4e4120b245p@chr4:104940057..104940067, +
8.97e-44FFCP PHASE1:Mm9::chr7:38969538..38969543,-#_47828f8efb2693d0df291fb1156664c3p@chr7:38969538..38969543, -
8.97e-44FFCP PHASE2:Mm9::chr7:38969538..38969543,-#_47828f8efb2693d0df291fb1156664c3p@chr7:38969538..38969543, -
4.15e-39FFCP PHASE2:Mm9::chr15:74647718..74647727,-#_527fbfc1af5dd70a703a040f800cae31p2@Gml
4.15e-39FFCP PHASE1:Mm9::chr15:74647718..74647727,-#_527fbfc1af5dd70a703a040f800cae31p2@Gml
1.17e-38FFCP PHASE2:Mm9::chr7:19152867..19152872,-#_ad37dd53e0954041498f2a3eb5af6dc3p5@Psg27
1.17e-38FFCP PHASE1:Mm9::chr7:19152867..19152872,-#_ad37dd53e0954041498f2a3eb5af6dc3p5@Psg27
2.09e-38FFCP PHASE2:Mm9::chr14:121693634..121693643,-#_2ad1d7c3c908ae1350e3f83cfeb9dfc8p@chr14:121693634..121693643, -
2.09e-38FFCP PHASE1:Mm9::chr14:121693634..121693643,-#_2ad1d7c3c908ae1350e3f83cfeb9dfc8p@chr14:121693634..121693643, -
4.98e-38FFCP PHASE1:Mm9::chr17:73681574..73681576,+#_3fa0ffcf5c756735e36d535a0e2aaeaap@chr17:73681574..73681576, +
4.98e-38FFCP PHASE2:Mm9::chr17:73681574..73681576,+#_3fa0ffcf5c756735e36d535a0e2aaeaap@chr17:73681574..73681576, +
6.64e-38FFCP PHASE1:Mm9::chr1:58810538..58810543,+#_abbe96a4ebe48b3d0db670d2c74ca648p@chr1:58810538..58810543, +
6.64e-38FFCP PHASE2:Mm9::chr1:58810538..58810543,+#_abbe96a4ebe48b3d0db670d2c74ca648p@chr1:58810538..58810543, +
1.18e-37FFCP PHASE2:Mm9::chr7:19152636..19152647,-#_f52bb65ef68465d104765b45afab13c7p3@Psg27
1.18e-37FFCP PHASE1:Mm9::chr7:19152636..19152647,-#_f52bb65ef68465d104765b45afab13c7p3@Psg27
3.67e-34FFCP PHASE2:Mm9::chr17:41017293..41017307,-#_9edc7f3dabc2fc3e279be0fc48510cabp@chr17:41017293..41017307, -
3.67e-34FFCP PHASE1:Mm9::chr17:41017293..41017307,-#_9edc7f3dabc2fc3e279be0fc48510cabp@chr17:41017293..41017307, -
7.89e-34FFCP PHASE2:Mm9::chr8:13351651..13351657,+#_8759e833e78682ac1eca7132e60b8cfep@chr8:13351651..13351657, +
7.89e-34FFCP PHASE1:Mm9::chr8:13351651..13351657,+#_8759e833e78682ac1eca7132e60b8cfep@chr8:13351651..13351657, +
7.89e-34FFCP PHASE1:Mm9::chr11:59700717..59700721,+#_8759e833e78682ac1eca7132e60b8cfep@chr11:59700717..59700721, +
7.89e-34FFCP PHASE2:Mm9::chr11:59700717..59700721,+#_8759e833e78682ac1eca7132e60b8cfep@chr11:59700717..59700721, +
1.02e-33FFCP PHASE2:Mm9::chr15:58184398..58184415,-#_861f189895222b3d984a1965178d68d7p@chr15:58184398..58184415, -
1.02e-33FFCP PHASE1:Mm9::chr15:58184398..58184415,-#_861f189895222b3d984a1965178d68d7p@chr15:58184398..58184415, -
1.31e-33FFCP PHASE2:Mm9::chr7:6120193..6120204,-#_965de4e6c67b378a2421dc29ed6d6afbp@chr7:6120193..6120204, -
1.31e-33FFCP PHASE1:Mm9::chr7:6120193..6120204,-#_965de4e6c67b378a2421dc29ed6d6afbp@chr7:6120193..6120204, -
1.69e-33FFCP PHASE2:Mm9::chr16:57199200..57199210,-#_0cfc9603cc102e8fb529cfe32a6d35fap@chr16:57199200..57199210, -
1.69e-33FFCP PHASE1:Mm9::chr16:57199200..57199210,-#_0cfc9603cc102e8fb529cfe32a6d35fap@chr16:57199200..57199210, -
2.18e-33FFCP PHASE2:Mm9::chr11:54787273..54787303,-#_8612f2f3c11c7425ea9f727780dfc532p@chr11:54787273..54787303, -
2.18e-33FFCP PHASE2:Mm9::chr1:195129567..195129580,+#_8612f2f3c11c7425ea9f727780dfc532p8@Lamb3
2.18e-33FFCP PHASE1:Mm9::chr11:54787273..54787303,-#_8612f2f3c11c7425ea9f727780dfc532p@chr11:54787273..54787303, -
2.18e-33FFCP PHASE1:Mm9::chr1:195129567..195129580,+#_8612f2f3c11c7425ea9f727780dfc532p8@Lamb3
2.8e-33FFCP PHASE2:Mm9::chr18:20714918..20714920,+#_e9ae44a4c4d92db088eab7b9ac351af3p@chr18:20714918..20714920, +
2.8e-33FFCP PHASE2:Mm9::chr7:19110105..19110113,-#_e9ae44a4c4d92db088eab7b9ac351af3p@chr7:19110105..19110113, -
2.8e-33FFCP PHASE1:Mm9::chr3:103636771..103636777,+#_e9ae44a4c4d92db088eab7b9ac351af3p@chr3:103636771..103636777, +
2.8e-33FFCP PHASE2:Mm9::chr6:113589357..113589371,-#_e9ae44a4c4d92db088eab7b9ac351af3p@chr6:113589357..113589371, -
2.8e-33FFCP PHASE1:Mm9::chr7:19110105..19110113,-#_e9ae44a4c4d92db088eab7b9ac351af3p@chr7:19110105..19110113, -
2.8e-33FFCP PHASE1:Mm9::chr18:20714918..20714920,+#_e9ae44a4c4d92db088eab7b9ac351af3p@chr18:20714918..20714920, +
2.8e-33FFCP PHASE1:Mm9::chr6:113589357..113589371,-#_e9ae44a4c4d92db088eab7b9ac351af3p@chr6:113589357..113589371, -
2.8e-33FFCP PHASE2:Mm9::chr3:103636771..103636777,+#_e9ae44a4c4d92db088eab7b9ac351af3p@chr3:103636771..103636777, +
3.61e-33FFCP PHASE1:Mm9::chr7:138141963..138141967,-#_1d8c93f2d766eb17eeeff14ec514f070p@chr7:138141963..138141967, -
3.61e-33FFCP PHASE2:Mm9::chr4:116494077..116494092,-#_1d8c93f2d766eb17eeeff14ec514f070p2@Hpdl
3.61e-33FFCP PHASE1:Mm9::chr4:116494077..116494092,-#_1d8c93f2d766eb17eeeff14ec514f070p2@Hpdl
3.61e-33FFCP PHASE2:Mm9::chr7:138141963..138141967,-#_1d8c93f2d766eb17eeeff14ec514f070p@chr7:138141963..138141967, -
4.64e-33FFCP PHASE2:Mm9::chr8:8533654..8533663,+#_153143f0cc874de657c3b2ab27663700p@chr8:8533654..8533663, +
4.64e-33FFCP PHASE1:Mm9::chr8:8533654..8533663,+#_153143f0cc874de657c3b2ab27663700p@chr8:8533654..8533663, +
7.68e-33FFCP PHASE1:Mm9::chr2:13415278..13415284,-#_d979d41aa131f194b5f2db15ee9818a4p@chr2:13415278..13415284, -
7.68e-33FFCP PHASE2:Mm9::chr2:13415278..13415284,-#_d979d41aa131f194b5f2db15ee9818a4p@chr2:13415278..13415284, -
7.68e-33FFCP PHASE2:Mm9::chr15:27670949..27670953,+#_d979d41aa131f194b5f2db15ee9818a4p@chr15:27670949..27670953, +
7.68e-33FFCP PHASE1:Mm9::chr15:27670949..27670953,+#_d979d41aa131f194b5f2db15ee9818a4p@chr15:27670949..27670953, +
1.16e-30FFCP PHASE1:Mm9::chr16:20695073..20695082,+#_96a7ecbbcbe90d5e616e3b060560ee11p11@Fam131a
1.16e-30FFCP PHASE2:Mm9::chr16:20695073..20695082,+#_96a7ecbbcbe90d5e616e3b060560ee11p11@Fam131a
1.83e-30FFCP PHASE1:Mm9::chr4:114914645..114914653,+#_aadbde217ee3194fc0561159ba7a3928p1@Cyp4a29-ps
1.83e-30FFCP PHASE2:Mm9::chr4:114914645..114914653,+#_aadbde217ee3194fc0561159ba7a3928p1@Cyp4a29-ps
2.3e-30FFCP PHASE2:Mm9::chr12:86479683..86479693,-#_67255c5e371f501624fa6ac4046a73b7p@chr12:86479683..86479693, -
2.3e-30FFCP PHASE2:Mm9::chr2:38469278..38469287,-#_67255c5e371f501624fa6ac4046a73b7p@chr2:38469278..38469287, -
2.3e-30FFCP PHASE1:Mm9::chr2:38469229..38469240,-#_67255c5e371f501624fa6ac4046a73b7p@chr2:38469229..38469240, -
2.3e-30FFCP PHASE1:Mm9::chr1:127346940..127346945,-#_67255c5e371f501624fa6ac4046a73b7p@chr1:127346940..127346945, -
2.3e-30FFCP PHASE2:Mm9::chr1:127346940..127346945,-#_67255c5e371f501624fa6ac4046a73b7p@chr1:127346940..127346945, -
2.3e-30FFCP PHASE1:Mm9::chr12:86479683..86479693,-#_67255c5e371f501624fa6ac4046a73b7p@chr12:86479683..86479693, -
2.3e-30FFCP PHASE2:Mm9::chr2:38469229..38469240,-#_67255c5e371f501624fa6ac4046a73b7p@chr2:38469229..38469240, -
2.3e-30FFCP PHASE1:Mm9::chr2:38469278..38469287,-#_67255c5e371f501624fa6ac4046a73b7p@chr2:38469278..38469287, -
3.62e-30FFCP PHASE1:Mm9::chr9:56730814..56730824,-#_0bb5cee73ac8688009173bdb5087c5bbp@chr9:56730814..56730824, -
3.62e-30FFCP PHASE1:Mm9::chr12:21502374..21502380,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr12:21502374..21502380, +
3.62e-30FFCP PHASE1:Mm9::chr13:32952878..32952890,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr13:32952878..32952890, +
3.62e-30FFCP PHASE2:Mm9::chr13:32952878..32952890,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr13:32952878..32952890, +
3.62e-30FFCP PHASE1:Mm9::chr16:20867079..20867087,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr16:20867079..20867087, +
3.62e-30FFCP PHASE2:Mm9::chr9:56730814..56730824,-#_0bb5cee73ac8688009173bdb5087c5bbp@chr9:56730814..56730824, -
3.62e-30FFCP PHASE2:Mm9::chr12:21502374..21502380,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr12:21502374..21502380, +
3.62e-30FFCP PHASE1:Mm9::chr2:11414279..11414290,-#_0bb5cee73ac8688009173bdb5087c5bbp@chr2:11414279..11414290, -
3.62e-30FFCP PHASE2:Mm9::chr2:11414279..11414290,-#_0bb5cee73ac8688009173bdb5087c5bbp@chr2:11414279..11414290, -
3.62e-30FFCP PHASE2:Mm9::chr16:20867079..20867087,+#_0bb5cee73ac8688009173bdb5087c5bbp@chr16:20867079..20867087, +
4.54e-30FFCP PHASE1:Mm9::chr3:89041849..89041862,-#_750fbab7c1e7e6d5a839cf5962c55657p@chr3:89041849..89041862, -
4.54e-30FFCP PHASE2:Mm9::chr3:89041849..89041862,-#_750fbab7c1e7e6d5a839cf5962c55657p@chr3:89041849..89041862, -
4.54e-30FFCP PHASE2:Mm9::chr6:82998517..82998522,+#_750fbab7c1e7e6d5a839cf5962c55657p2@Loxl3
4.54e-30FFCP PHASE1:Mm9::chr6:82998517..82998522,+#_750fbab7c1e7e6d5a839cf5962c55657p2@Loxl3
5.61e-30FFCP PHASE1:Mm9::chr9:104230353..104230354,-#_071b2322056e60329663048741cde51fp@chr9:104230353..104230354, -
5.61e-30FFCP PHASE2:Mm9::chr9:104230353..104230354,-#_071b2322056e60329663048741cde51fp@chr9:104230353..104230354, -
5.7e-30FFCP PHASE2:Mm9::chr17:37004048..37004055,-#_4cc817102e9ccce43ab9d9f38f391355p4@Trim15
5.7e-30FFCP PHASE2:Mm9::chr10:61337613..61337627,-#_4cc817102e9ccce43ab9d9f38f391355p@chr10:61337613..61337627, -
5.7e-30FFCP PHASE1:Mm9::chr10:61337613..61337627,-#_4cc817102e9ccce43ab9d9f38f391355p@chr10:61337613..61337627, -
5.7e-30FFCP PHASE1:Mm9::chr17:37004048..37004055,-#_4cc817102e9ccce43ab9d9f38f391355p4@Trim15
7.14e-30FFCP PHASE1:Mm9::chr10:79568311..79568322,-#_e7b2e854e6a2c1fae62219cf04ad6e71p@chr10:79568311..79568322, -
7.14e-30FFCP PHASE2:Mm9::chr17:24112500..24112507,-#_e7b2e854e6a2c1fae62219cf04ad6e71p3@Prss30
7.14e-30FFCP PHASE2:Mm9::chr10:79568311..79568322,-#_e7b2e854e6a2c1fae62219cf04ad6e71p@chr10:79568311..79568322, -
7.14e-30FFCP PHASE1:Mm9::chr17:24112500..24112507,-#_e7b2e854e6a2c1fae62219cf04ad6e71p3@Prss30
7.89e-30FFCP PHASE1:Mm9::chr10:126566696..126566708,+#_a50488b8b086d083c47275df9a398a93p@chr10:126566696..126566708, +
7.89e-30FFCP PHASE2:Mm9::chr10:126566696..126566708,+#_a50488b8b086d083c47275df9a398a93p@chr10:126566696..126566708, +
1.12e-29FFCP PHASE1:Mm9::chr8:25506263..25506266,+#_a630453c3e25d493c689ed68873dffd3p@chr8:25506263..25506266, +
1.12e-29FFCP PHASE2:Mm9::chr8:25506263..25506266,+#_a630453c3e25d493c689ed68873dffd3p@chr8:25506263..25506266, +
1.4e-29FFCP PHASE2:Mm9::chr5:66443992..66444014,-#_e5f365b4653f5571f03f01c965446816p@chr5:66443992..66444014, -
1.4e-29FFCP PHASE1:Mm9::chr5:66443992..66444014,-#_e5f365b4653f5571f03f01c965446816p@chr5:66443992..66444014, -

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