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{{f5samples
{{f5samples
|id=FF:11916-125G8
|DRA_sample_Accession=CAGE@SAMD00005387
|name=CD4+CD25+CD45RA- memory regulatory T cells expanded, donor2
|accession_numbers=CAGE;DRX008182;DRR009054;DRZ000479;DRZ001864;DRZ011829;DRZ013214
|sample_id=11916
|ancestors_in_anatomy_facet=
|rna_tube_id=125G8
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003
|rna_box=125
|rna_position=G8
|sample_cell_lot=
|sample_cell_catalog=
|sample_company=
|rna_lot_number=59-60
|rna_catalog_number=
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_dev_stage=
|sample_tissue=blood
|sample_donor(cell lot)=
|sample_sex=male
|sample_age=23
|sample_ethnicity=
|rna_rin=
|rna_od260/230=1.68
|rna_od260/280=2.06
|sample_cell_type=T cell
|sample_cell_line=
|sample_collaboration=Michael Rehli (University of Regensberg)
|sample_experimental_condition=
|sample_disease=
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=6.3956
|rna_concentration=0.63956
|sample_note=
|profile_hcage=CNhs13811,LSID1092,release014,COMPLETED
|profile_cagescan=
|profile_srnaseq=
|profile_rnaseq=
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000084,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000624,CL:0000723,CL:0000738,CL:0000789,CL:0000790,CL:0000791,CL:0000792,CL:0000815,CL:0000827,CL:0000837,CL:0000838,CL:0000898,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371,CL:0002419,CL:0002420,CL:0002677
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|sample_description=
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001
|comment=Changed from previous label. TODO: full classification
|created_by=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|expression_enrichment_score=chrX:49121165..49121179,-!p1@FOXP3!2.57!373.39!FOXP3;;chr17:37934204..37934241,-!p3@IKZF3!1.83!67.38!IKZF3;;chr17:37934365..37934387,-!p2@IKZF3!1.83!67.38!IKZF3;;chr16:79634624..79634642,-!p1@MAF!1.81!237.61!MAF;;chr16:79634595..79634620,-!p2@MAF!1.77!103.50!MAF;;chr7:50343634..50343717,+!p2@IKZF1!1.77!57.90!IKZF1;;chr10:8096631..8096660,+!p1@GATA3!1.76!68.40!GATA3;;chr10:8096772..8096787,+!p2@GATA3!1.71!59.18!GATA3;;chr2:231090433..231090469,+!p1@SP140!1.71!50.85!SP140;;chr14:75988771..75988826,+!p1@BATF!1.68!61.61!BATF;;chr14:75988831..75988847,+!p2@BATF!1.62!40.99!BATF;;chr3:18486354..18486377,-!p2@SATB1!1.60!47.91!SATB1;;chr20:50159198..50159299,-!p1@NFATC2!1.50!43.94!NFATC2;;chr19:19779619..19779670,+!p1@ZNF101!1.45!73.91!ZNF101;;chr9:117150254..117150271,-!p1@AKNA!1.45!71.99!AKNA;;chrY:21906594..21906622,-!p1@KDM5D!1.43!26.13!KDM5D;;chr1:25256756..25256774,-!p1@RUNX3!1.42!46.63!RUNX3;;chr20:56195474..56195506,-!p1@ZBP1!1.39!23.57!ZBP1;;chr7:50344251..50344288,+!p3@IKZF1!1.38!23.18!IKZF1;;chr2:231090471..231090504,+!p2@SP140!1.38!22.80!SP140;;chr19:16435625..16435682,+!p1@KLF2!1.37!689.39!KLF2;;chr15:60884706..60884743,-!p1@RORA!1.37!113.75!RORA;;chr17:38020392..38020477,-!p1@IKZF3!1.37!22.54!IKZF3;;chr17:37934280..37934299,-!p6@IKZF3!1.35!21.52!IKZF3;;chr6:391743..391759,+!p1@IRF4!1.35!21.39!IRF4;;chr12:56415246..56415286,+!p2@IKZF4!1.35!21.14!IKZF4;;chr7:50348268..50348366,+!p4@IKZF1!1.32!19.85!IKZF1;;chr3:18480217..18480239,-!p3@SATB1!1.31!19.60!SATB1;;chr7:50343895..50343936,+!p5@IKZF1!1.29!18.57!IKZF1;;chr2:192015750..192015793,-!p2@STAT4!1.28!24.34!STAT4;;chr10:35484053..35484076,+!p1@CREM!1.26!42.27!CREM;;chr16:68119324..68119364,+!p1@NFATC3!1.23!69.81!NFATC3;;chr19:19729477..19729542,-!p1@PBX4!1.23!33.82!PBX4;;chr6:106546808..106546833,+!p3@PRDM1!1.23!20.24!PRDM1;;chr16:88752861..88752884,-!p2@SNAI3!1.23!16.01!SNAI3;;chr16:88752889..88752921,-!p1@SNAI3!1.22!18.19!SNAI3;;chr14:99738138..99738163,-!p1@BCL11B!1.22!15.63!BCL11B;;chr17:38020557..38020572,-!p4@IKZF3!1.21!15.24!IKZF3;;chr1:23857698..23857733,-!p1@E2F2!1.20!26.90!E2F2;;chr20:56195525..56195556,-!p2@ZBP1!1.20!14.86!ZBP1;;chr17:37934188..37934202,-!p8@IKZF3!1.19!14.60!IKZF3;;chr16:79634581..79634592,-!p4@MAF!1.19!14.35!MAF;;chr19:36204309..36204335,+!p1@ZBTB32!1.19!14.35!ZBTB32;;chr2:192015701..192015743,-!p1@STAT4!1.18!19.60!STAT4;;chr1:92951607..92951661,-!p1@GFI1!1.18!14.22!GFI1;;chr17:38020516..38020544,-!p5@IKZF3!1.18!14.09!IKZF3;;chr3:63953435..63953499,+!p1@ATXN7!1.18!14.09!ATXN7;;chr16:79633894..79633954,-!p3@MAF!1.16!25.75!MAF;;chr7:137620650..137620677,-!p3@CREB3L2!1.16!13.32!CREB3L2;;chr19:19779686..19779697,+!p3@ZNF101!1.15!15.37!ZNF101;;chr3:12330560..12330579,+!p1@PPARG!1.15!15.11!PPARG;;chr7:50344289..50344323,+!p1@IKZF1!1.13!12.42!IKZF1;;chr3:141105705..141105770,+!p4@ZBTB38!1.12!14.99!ZBTB38;;chr17:45810594..45810608,+!p1@TBX21!1.12!12.04!TBX21;;chr13:41593425..41593480,-!p1@ELF1!1.10!73.91!ELF1;;chr11:47236584..47236679,+!p1@DDB2!1.05!112.98!DDB2;;chr7:77428066..77428132,+!p2@PHTF2!1.03!63.92!PHTF2;;chr10:8095593..8095625,+!p3@GATA3!1.03!11.53!GATA3;;chr12:56415287..56415300,+!p5@IKZF4!1.03!9.73!IKZF4;;chr6:106546731..106546755,+!p5@PRDM1!1.03!9.61!PRDM1;;chr21:36421535..36421610,-!p2@RUNX1!1.01!33.69!RUNX1;;chr4:81104895..81104920,+!p2@PRDM8!0.99!13.19!PRDM8;;chr14:99738059..99738086,-!p2@BCL11B!0.98!8.58!BCL11B;;chr6:106547079..106547114,+!p9@PRDM1!0.97!8.33!PRDM1;;chr3:71355163..71355209,-!p5@FOXP1!0.95!11.02!FOXP1;;chr2:97202991..97203043,+!p3@ARID5A!0.95!7.81!ARID5A;;chr8:60031619..60031676,-!p1@TOX!0.94!17.29!TOX;;chr2:242556880..242556899,-!p5@THAP4!0.94!7.69!THAP4;;chr6:106546834..106546850,+!p4@PRDM1!0.93!7.56!PRDM1;;chr7:137620684..137620711,-!p4@CREB3L2!0.91!7.05!CREB3L2;;chr19:42636586..42636607,-!p1@POU2F2!0.90!19.98!POU2F2;;chr3:48282587..48282603,+!p1@ZNF589!0.89!31.77!ZNF589;;chr17:56565257..56565283,-!p2@HSF5!0.89!6.79!HSF5;;chr7:50343864..50343888,+!p7@IKZF1!0.89!6.79!IKZF1;;chr11:128563948..128564003,+!p1@FLI1!0.88!83.77!FLI1;;chr17:1959369..1959388,+!p2@HIC1!0.88!18.06!HIC1;;chr4:185395633..185395651,-!p2@IRF2!0.88!10.76!IRF2;;chrY:2803415..2803468,+!p1@ZFY!0.87!6.40!ZFY;;chr11:128392085..128392232,-!p1@ETS1!0.86!221.85!ETS1;;chr10:35484804..35484902,+!p2@CREM!0.86!25.23!CREM;;chr6:15249128..15249177,+!p4@JARID2!0.86!11.53!JARID2;;chr6:106546786..106546802,+!p6@PRDM1!0.86!6.28!PRDM1;;chr7:50344144..50344157,+!p6@IKZF1!0.86!6.28!IKZF1;;chr9:20621927..20621996,-!p3@MLLT3!0.85!10.50!MLLT3;;chr14:99737850..99737852,-!p3@BCL11B!0.84!5.89!BCL11B;;chr5:131826457..131826514,-!p1@IRF1!0.83!244.14!IRF1;;chr3:18480173..18480189,-!p6@SATB1!0.83!5.76!SATB1;;chr19:16435735..16435773,+!p4@KLF2!0.83!5.76!KLF2;;chr10:104154246..104154347,+!p3@NFKB2!0.81!35.87!NFKB2;;chr10:8097321..8097348,+!p4@GATA3!0.81!5.51!GATA3;;chr1:151798546..151798590,-!p2@RORC!0.80!5.38!RORC;;chr4:57522674..57522699,-!p5@HOPX!0.80!5.25!HOPX;;chr2:238600933..238600985,+!p3@LRRFIP1!0.79!30.61!LRRFIP1;;chr9:20622444.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|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988
|fonse_cell_line=
|fonse_cell_line=
|fonse_cell_line_closure=
|fonse_cell_line_closure=
Line 66: Line 40:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
|fonse_treatment_closure=
|top_motifs=ZBTB16:2.74253672649;CDX1,2,4:2.22051977968;PAX3,7:2.1255853689;ELF1,2,4:2.09584340837;PITX1..3:1.76032529528;NKX6-1,2:1.73193930703;IKZF2:1.70261644835;RUNX1..3:1.6882330424;RORA:1.67195658522;FOXP1:1.66803134185;TLX2:1.63789460427;ETS1,2:1.33791969408;POU2F1..3:1.28992079484;PAX4:1.28078695382;TOPORS:1.24362174169;SPI1:1.17657795722;IRF1,2:1.13285088223;PDX1:1.13014663743;FOX{F1,F2,J1}:1.09713376378;AIRE:1.08363732361;DMAP1_NCOR{1,2}_SMARC:1.07666228867;POU1F1:1.06362599435;BPTF:1.01680026976;NKX3-1:0.912313508057;GATA6:0.859011187791;ELK1,4_GABP{A,B1}:0.822874881054;CRX:0.806092021694;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.793216521923;HMX1:0.785317682496;E2F1..5:0.699357199887;STAT1,3:0.671996217385;SPIB:0.638714922653;LMO2:0.61171044295;PBX1:0.596376960567;STAT2,4,6:0.579471386969;BREu{core}:0.576486569948;ZNF384:0.560674220731;STAT5{A,B}:0.551335700489;MYOD1:0.542626540832;YY1:0.536398340103;NANOG{mouse}:0.514414559509;CREB1:0.502547536779;ZEB1:0.481202446686;FOXO1,3,4:0.451607718404;FOX{D1,D2}:0.448567789963;FOXM1:0.376443220198;ATF5_CREB3:0.366308600475;NFKB1_REL_RELA:0.353332607478;SNAI1..3:0.349069945452;IRF7:0.347376776537;EVI1:0.320574580296;HES1:0.301985851359;NFY{A,B,C}:0.294530749866;NKX2-2,8:0.282520990198;OCT4_SOX2{dimer}:0.280710823532;PAX8:0.267024793128;MYB:0.252844944536;TGIF1:0.217336862277;FOXQ1:0.217321164219;RFX2..5_RFXANK_RFXAP:0.209115700127;PAX2:0.173586977572;NR5A1,2:0.167523440578;SMAD1..7,9:0.161314216834;SOX5:0.148912969012;HOX{A6,A7,B6,B7}:0.130625379827;SREBF1,2:0.123382267041;LEF1_TCF7_TCF7L1,2:0.10064701807;FOXP3:0.0679160032101;CUX2:0.0635881419217;DBP:0.0631183331576;FOXD3:0.00228851462359;EP300:-0.0155901597556;NRF1:-0.044075824823;FOX{I1,J2}:-0.0480652352817;TP53:-0.0531291812021;SPZ1:-0.0582354986915;ZNF423:-0.100349970888;GFI1:-0.141152428135;HNF4A_NR2F1,2:-0.141749023658;FOXA2:-0.156165836781;ZNF148:-0.158265091247;ATF4:-0.1583027534;ZNF143:-0.175731568817;HAND1,2:-0.193204842048;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.194321143101;T:-0.198429456496;FOXN1:-0.214372397676;RXRA_VDR{dimer}:-0.218881357198;RREB1:-0.225717670866;ONECUT1,2:-0.230034913802;JUN:-0.23777521131;GCM1,2:-0.243434637205;NFATC1..3:-0.26394209466;CDC5L:-0.265347022267;NFE2L1:-0.265527614334;GLI1..3:-0.28447574189;ATF2:-0.302954802738;NR1H4:-0.378422844854;AHR_ARNT_ARNT2:-0.399732213845;TAL1_TCF{3,4,12}:-0.404640739348;MYFfamily:-0.417284636695;NR3C1:-0.424129106411;UFEwm:-0.434342155126;ALX1:-0.437729280043;PRRX1,2:-0.438865633113;TFDP1:-0.444616559638;SRF:-0.449043827682;TFCP2:-0.459753363888;NFE2:-0.47114238861;CEBPA,B_DDIT3:-0.473487808889;NFIL3:-0.478037099584;NKX2-1,4:-0.489271245831;ARID5B:-0.492253903065;HNF1A:-0.492497154976;FOS_FOS{B,L1}_JUN{B,D}:-0.534630723033;AR:-0.541212852289;PPARG:-0.544637891077;BACH2:-0.547201733339;ALX4:-0.548641093923;HOXA9_MEIS1:-0.563523176045;POU3F1..4:-0.586487978005;ATF6:-0.591361786492;SOX2:-0.622045722607;SOX{8,9,10}:-0.680423424962;XCPE1{core}:-0.685735244169;ESR1:-0.718162018611;NHLH1,2:-0.778572512042;REST:-0.781597269365;NFIX:-0.785701476638;ZNF238:-0.796379908509;NFE2L2:-0.798825632275;NKX2-3_NKX2-5:-0.799038797616;FOSL2:-0.810490648407;TFAP4:-0.813644019279;PRDM1:-0.822095315385;ZBTB6:-0.82977261454;POU5F1:-0.834664209908;HMGA1,2:-0.845664270508;VSX1,2:-0.850378299269;NR6A1:-0.869430876758;RFX1:-0.876773352144;PAX5:-0.899093442912;PAX6:-0.906022994088;GATA4:-0.915756938698;GFI1B:-0.92097781855;TEF:-0.922343243593;MAFB:-0.934499882692;bHLH_family:-0.939792941497;HLF:-0.951861815006;LHX3,4:-0.962368636962;HIF1A:-0.974914256631;MED-1{core}:-0.977080916275;KLF4:-0.984813363896;MYBL2:-0.986226925357;ADNP_IRX_SIX_ZHX:-1.01520877922;HBP1_HMGB_SSRP1_UBTF:-1.0421500589;NANOG:-1.04756113415;EGR1..3:-1.0583453712;MEF2{A,B,C,D}:-1.07147938111;FOXL1:-1.07668307277;HSF1,2:-1.1327111334;EBF1:-1.13990025819;ZFP161:-1.14178291465;MTF1:-1.16590736614;ESRRA:-1.2030229622;MTE{core}:-1.22747999397;MAZ:-1.2374602786;HOX{A5,B5}:-1.23788931042;TFAP2B:-1.27377118999;MZF1:-1.29027774607;GTF2A1,2:-1.32020596911;GZF1:-1.3481618527;POU6F1:-1.3534055973;GTF2I:-1.35903796665;TFAP2{A,C}:-1.37246389803;HIC1:-1.38191115902;TBP:-1.3847862927;HOX{A4,D4}:-1.39847569416;TBX4,5:-1.41197843535;ZIC1..3:-1.44695395132;SOX17:-1.51915420206;EN1,2:-1.55364539189;PATZ1:-1.60271746269;PAX1,9:-1.61194522208;SP1:-1.64687669958;RXR{A,B,G}:-1.64756349558;TEAD1:-1.68029231953;RBPJ:-1.7353839908;TLX1..3_NFIC{dimer}:-1.74253568982;NKX3-2:-1.84798369112;IKZF1:-2.1148263193;XBP1:-2.31219743813
|comment=Changed from previous label. TODO: full classification
|created_by=
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|id=FF:11916-125G8
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|name=CD4+CD25+CD45RA- memory regulatory T cells expanded, donor2
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|rna_box=125
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|rna_concentration=0.63956
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=59-60
|rna_od260/230=1.68
|rna_od260/280=2.06
|rna_position=G8
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|rna_sample_type=total RNA
|rna_tube_id=125G8
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|sample_age=23
|sample_category=primary cells
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|sample_cell_type=T cell
|sample_collaboration=Michael Rehli (University of Regensberg)
|sample_company=
|sample_description=
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|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.72616876404556e-232!GO:0043227;membrane-bound organelle;7.64613075627999e-201!GO:0043231;intracellular membrane-bound organelle;1.59481811719884e-200!GO:0043226;organelle;1.38641791367283e-188!GO:0043229;intracellular organelle;5.60517233019098e-188!GO:0005737;cytoplasm;8.1340561383435e-159!GO:0044422;organelle part;4.35673551339393e-135!GO:0044446;intracellular organelle part;2.21261728439804e-133!GO:0044444;cytoplasmic part;8.79703294544519e-112!GO:0032991;macromolecular complex;2.88161666572645e-103!GO:0044237;cellular metabolic process;4.95440380371253e-96!GO:0043170;macromolecule metabolic process;1.16578334701566e-94!GO:0005634;nucleus;1.16578334701566e-94!GO:0044238;primary metabolic process;8.48602318048166e-93!GO:0030529;ribonucleoprotein complex;5.32943959702085e-86!GO:0044428;nuclear part;3.28096183162264e-77!GO:0003723;RNA binding;1.41577025573098e-74!GO:0043233;organelle lumen;3.47196397974467e-67!GO:0031974;membrane-enclosed lumen;3.47196397974467e-67!GO:0005515;protein binding;1.54897684340278e-63!GO:0005739;mitochondrion;1.60471403780324e-63!GO:0043283;biopolymer metabolic process;4.42812511684248e-61!GO:0006412;translation;7.03178407915302e-56!GO:0019538;protein metabolic process;8.03282704640672e-54!GO:0043234;protein complex;3.11525201708195e-53!GO:0044267;cellular protein metabolic process;8.54250751377306e-51!GO:0044260;cellular macromolecule metabolic process;1.47152187120936e-49!GO:0005840;ribosome;1.80946651024876e-49!GO:0006396;RNA processing;2.22074673435923e-49!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.75822152924944e-48!GO:0033036;macromolecule localization;9.01295182934909e-48!GO:0010467;gene expression;1.84139333419425e-47!GO:0015031;protein transport;5.85014171997067e-47!GO:0045184;establishment of protein localization;3.02512926507296e-45!GO:0008104;protein localization;1.32038887960062e-44!GO:0031981;nuclear lumen;1.70701746725728e-44!GO:0044429;mitochondrial part;2.77061624261498e-44!GO:0031090;organelle membrane;3.83434795769458e-44!GO:0003735;structural constituent of ribosome;3.9030816439697e-44!GO:0016071;mRNA metabolic process;3.28272605361339e-43!GO:0009059;macromolecule biosynthetic process;9.50001801652655e-43!GO:0031967;organelle envelope;2.27659607520105e-42!GO:0031975;envelope;5.49024454329336e-42!GO:0006259;DNA metabolic process;9.56950519371076e-40!GO:0033279;ribosomal subunit;7.25974241343794e-39!GO:0006397;mRNA processing;9.11088618400046e-37!GO:0008380;RNA splicing;1.26374540859845e-36!GO:0005829;cytosol;3.98897322440214e-36!GO:0046907;intracellular transport;4.35623856005855e-36!GO:0016043;cellular component organization and biogenesis;1.61373200408172e-35!GO:0044249;cellular biosynthetic process;3.91900715561242e-35!GO:0009058;biosynthetic process;4.39274277687283e-35!GO:0006886;intracellular protein transport;3.35013759696351e-33!GO:0065003;macromolecular complex assembly;4.56675026062285e-33!GO:0003676;nucleic acid binding;3.09962389648716e-31!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.60750203476319e-29!GO:0006996;organelle organization and biogenesis;1.89022565222349e-29!GO:0022607;cellular component assembly;3.33458536794897e-29!GO:0005740;mitochondrial envelope;5.33081390994642e-29!GO:0000166;nucleotide binding;9.93708340661302e-29!GO:0005654;nucleoplasm;1.00693816054275e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.26295751869681e-28!GO:0031966;mitochondrial membrane;9.0854253979265e-28!GO:0005681;spliceosome;9.96441556642625e-28!GO:0019866;organelle inner membrane;2.02296987530625e-27!GO:0043228;non-membrane-bound organelle;7.52503786204726e-27!GO:0043232;intracellular non-membrane-bound organelle;7.52503786204726e-27!GO:0006915;apoptosis;7.78792044481715e-27!GO:0012501;programmed cell death;8.04942057314868e-27!GO:0051641;cellular localization;2.0205042544184e-26!GO:0007049;cell cycle;2.49605294720592e-26!GO:0051649;establishment of cellular localization;2.89239823879693e-26!GO:0044445;cytosolic part;1.47130161328829e-25!GO:0008219;cell death;1.63187948771785e-25!GO:0016265;death;1.63187948771785e-25!GO:0005743;mitochondrial inner membrane;1.09719072984772e-24!GO:0005694;chromosome;7.80995681194692e-23!GO:0006512;ubiquitin cycle;8.12791756104064e-23!GO:0006974;response to DNA damage stimulus;1.45718366317806e-22!GO:0006119;oxidative phosphorylation;1.86332649252566e-22!GO:0016070;RNA metabolic process;6.71627313768938e-22!GO:0044451;nucleoplasm part;7.97937354554747e-22!GO:0032553;ribonucleotide binding;8.1251578728362e-22!GO:0032555;purine ribonucleotide binding;8.1251578728362e-22!GO:0017076;purine nucleotide binding;2.36923568428548e-21!GO:0044427;chromosomal part;2.39356312914e-21!GO:0043412;biopolymer modification;4.7181108249354e-21!GO:0022402;cell cycle process;4.93644267644045e-21!GO:0015935;small ribosomal subunit;2.22676449285139e-20!GO:0051276;chromosome organization and biogenesis;2.24403089986914e-20!GO:0005524;ATP binding;2.96084470163169e-20!GO:0044455;mitochondrial membrane part;3.34298644223238e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.96033102655115e-20!GO:0016462;pyrophosphatase activity;5.14934424720023e-20!GO:0022618;protein-RNA complex assembly;6.25986641290814e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;6.69547625297224e-20!GO:0044265;cellular macromolecule catabolic process;8.44015641184567e-20!GO:0017111;nucleoside-triphosphatase activity;9.65153143775395e-20!GO:0015934;large ribosomal subunit;1.18559344680559e-19!GO:0032559;adenyl ribonucleotide binding;2.70103180012916e-19!GO:0042981;regulation of apoptosis;8.92687246193854e-19!GO:0006464;protein modification process;9.81529861206709e-19!GO:0031980;mitochondrial lumen;9.81529861206709e-19!GO:0005759;mitochondrial matrix;9.81529861206709e-19!GO:0016874;ligase activity;1.11839661296035e-18!GO:0030554;adenyl nucleotide binding;1.20217579510248e-18!GO:0006281;DNA repair;1.36283338852153e-18!GO:0043067;regulation of programmed cell death;1.64168435705724e-18!GO:0043687;post-translational protein modification;3.00154457227226e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;3.54660335363884e-17!GO:0000278;mitotic cell cycle;4.33517108999487e-17!GO:0006605;protein targeting;4.68341019560878e-17!GO:0012505;endomembrane system;4.90793928432295e-17!GO:0005746;mitochondrial respiratory chain;6.54600816542436e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;6.54600816542436e-17!GO:0019941;modification-dependent protein catabolic process;6.54940189824935e-17!GO:0043632;modification-dependent macromolecule catabolic process;6.54940189824935e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.39365816305893e-16!GO:0044257;cellular protein catabolic process;1.80107284679056e-16!GO:0006323;DNA packaging;2.03421189673718e-16!GO:0043285;biopolymer catabolic process;2.0677321853587e-16!GO:0005730;nucleolus;2.2137754769755e-16!GO:0008135;translation factor activity, nucleic acid binding;2.43448329074879e-16!GO:0000502;proteasome complex (sensu Eukaryota);2.6231782566652e-16!GO:0008134;transcription factor binding;5.45729433795306e-16!GO:0009057;macromolecule catabolic process;7.37236326099973e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.18837981031313e-15!GO:0003954;NADH dehydrogenase activity;1.18837981031313e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.18837981031313e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.38740817042986e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.41835277893884e-15!GO:0006457;protein folding;2.20561736215451e-15!GO:0006913;nucleocytoplasmic transport;2.25025950560909e-15!GO:0016887;ATPase activity;3.99648822393127e-15!GO:0042623;ATPase activity, coupled;4.34485647058379e-15!GO:0051169;nuclear transport;4.89064112124369e-15!GO:0009719;response to endogenous stimulus;2.18837494604995e-14!GO:0022403;cell cycle phase;2.7059973135983e-14!GO:0016604;nuclear body;3.65843059863181e-14!GO:0005635;nuclear envelope;3.74898687237829e-14!GO:0000785;chromatin;3.90832987967272e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.60341984675891e-14!GO:0042775;organelle ATP synthesis coupled electron transport;7.31333224675752e-14!GO:0042773;ATP synthesis coupled electron transport;7.31333224675752e-14!GO:0065004;protein-DNA complex assembly;7.78486695801863e-14!GO:0000087;M phase of mitotic cell cycle;7.92763905387678e-14!GO:0044248;cellular catabolic process;8.55938914348752e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.26519836143891e-13!GO:0045271;respiratory chain complex I;1.26519836143891e-13!GO:0005747;mitochondrial respiratory chain complex I;1.26519836143891e-13!GO:0005761;mitochondrial ribosome;1.41386325348405e-13!GO:0000313;organellar ribosome;1.41386325348405e-13!GO:0007067;mitosis;1.52579704195348e-13!GO:0006333;chromatin assembly or disassembly;1.64256728829398e-13!GO:0048770;pigment granule;1.84679386352721e-13!GO:0042470;melanosome;1.84679386352721e-13!GO:0051726;regulation of cell cycle;2.13033578546755e-13!GO:0003743;translation initiation factor activity;2.37509008567433e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;2.49935382130239e-13!GO:0000375;RNA splicing, via transesterification reactions;2.49935382130239e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.49935382130239e-13!GO:0000074;regulation of progression through cell cycle;3.65765842421086e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.16637594893878e-13!GO:0006413;translational initiation;5.70896607122686e-13!GO:0031965;nuclear membrane;5.81597271243677e-13!GO:0006793;phosphorus metabolic process;6.38971999448687e-13!GO:0006796;phosphate metabolic process;6.38971999448687e-13!GO:0030163;protein catabolic process;8.28050991971508e-13!GO:0000279;M phase;7.61546954696484e-12!GO:0051186;cofactor metabolic process;9.07399591453e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.48379768700931e-12!GO:0051301;cell division;1.06280345101715e-11!GO:0044453;nuclear membrane part;1.2586219325191e-11!GO:0050794;regulation of cellular process;1.2586219325191e-11!GO:0005794;Golgi apparatus;1.29015798852521e-11!GO:0048193;Golgi vesicle transport;2.00646153036253e-11!GO:0006260;DNA replication;3.43394451111507e-11!GO:0017038;protein import;3.70968870734724e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.63288909097266e-11!GO:0051082;unfolded protein binding;4.64283979948933e-11!GO:0004386;helicase activity;5.33951249757224e-11!GO:0016310;phosphorylation;6.73252331817535e-11!GO:0006446;regulation of translational initiation;7.15457460411786e-11!GO:0006334;nucleosome assembly;8.11443579419355e-11!GO:0042254;ribosome biogenesis and assembly;8.73581828688813e-11!GO:0016607;nuclear speck;9.33608018835992e-11!GO:0008639;small protein conjugating enzyme activity;1.02554805895278e-10!GO:0005783;endoplasmic reticulum;1.13378164046349e-10!GO:0031497;chromatin assembly;2.31294774074312e-10!GO:0004842;ubiquitin-protein ligase activity;2.47398733991768e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.54089326527227e-10!GO:0019787;small conjugating protein ligase activity;2.96457962562647e-10!GO:0051246;regulation of protein metabolic process;3.02391894766351e-10!GO:0016568;chromatin modification;3.58855247839137e-10!GO:0044432;endoplasmic reticulum part;4.51296569481754e-10!GO:0043069;negative regulation of programmed cell death;5.00532408259799e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.05048016441224e-10!GO:0007243;protein kinase cascade;6.03048132223871e-10!GO:0043066;negative regulation of apoptosis;7.20420556442451e-10!GO:0006916;anti-apoptosis;9.55001776950245e-10!GO:0005643;nuclear pore;9.84423570333641e-10!GO:0008026;ATP-dependent helicase activity;1.42611187321293e-09!GO:0019829;cation-transporting ATPase activity;1.8605309593064e-09!GO:0016787;hydrolase activity;1.99147618214881e-09!GO:0043566;structure-specific DNA binding;2.29305429507897e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.36308130816901e-09!GO:0003712;transcription cofactor activity;2.9103705357255e-09!GO:0006732;coenzyme metabolic process;3.36723294787513e-09!GO:0008565;protein transporter activity;4.08079491728256e-09!GO:0009259;ribonucleotide metabolic process;4.74324367964552e-09!GO:0016740;transferase activity;4.88940814351912e-09!GO:0016192;vesicle-mediated transport;6.1989880469053e-09!GO:0005768;endosome;7.32014632249676e-09!GO:0006917;induction of apoptosis;8.0985019988898e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;9.16420702540135e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.25335845540476e-09!GO:0043065;positive regulation of apoptosis;1.00966863420232e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.24296224772057e-08!GO:0050657;nucleic acid transport;1.24296224772057e-08!GO:0051236;establishment of RNA localization;1.24296224772057e-08!GO:0050658;RNA transport;1.24296224772057e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.24817542217653e-08!GO:0006399;tRNA metabolic process;1.331107964367e-08!GO:0006164;purine nucleotide biosynthetic process;1.37769768107408e-08!GO:0048523;negative regulation of cellular process;1.38634840374279e-08!GO:0051170;nuclear import;1.39318969228163e-08!GO:0012502;induction of programmed cell death;1.39318969228163e-08!GO:0006163;purine nucleotide metabolic process;1.45198187970729e-08!GO:0006403;RNA localization;1.54775890761633e-08!GO:0043068;positive regulation of programmed cell death;1.58985902829059e-08!GO:0009260;ribonucleotide biosynthetic process;1.68751094448883e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.06880217446477e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.10713894954855e-08!GO:0009055;electron carrier activity;2.17648505230238e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.2149673637058e-08!GO:0006606;protein import into nucleus;2.41825608888956e-08!GO:0003697;single-stranded DNA binding;2.49641727310654e-08!GO:0005789;endoplasmic reticulum membrane;2.50509589650715e-08!GO:0065002;intracellular protein transport across a membrane;2.68417208945747e-08!GO:0016881;acid-amino acid ligase activity;2.72349273034571e-08!GO:0046930;pore complex;2.91520583005444e-08!GO:0065009;regulation of a molecular function;3.14805600167519e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.30698657608231e-08!GO:0009150;purine ribonucleotide metabolic process;3.6896647994883e-08!GO:0015986;ATP synthesis coupled proton transport;4.27171482661424e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.27171482661424e-08!GO:0030532;small nuclear ribonucleoprotein complex;5.79418944993845e-08!GO:0000786;nucleosome;7.96884616824125e-08!GO:0004298;threonine endopeptidase activity;8.09755419890148e-08!GO:0051188;cofactor biosynthetic process;1.6768643443278e-07!GO:0048519;negative regulation of biological process;2.0996991094184e-07!GO:0032446;protein modification by small protein conjugation;3.16259676880025e-07!GO:0016779;nucleotidyltransferase activity;3.16532260103822e-07!GO:0016072;rRNA metabolic process;3.18011398722688e-07!GO:0009056;catabolic process;3.18939053572522e-07!GO:0007242;intracellular signaling cascade;3.30870501096471e-07!GO:0051028;mRNA transport;3.3988936707152e-07!GO:0009060;aerobic respiration;3.46539847195668e-07!GO:0006754;ATP biosynthetic process;3.5859771717703e-07!GO:0006753;nucleoside phosphate metabolic process;3.5859771717703e-07!GO:0006364;rRNA processing;3.69711829138237e-07!GO:0050789;regulation of biological process;3.70559699728801e-07!GO:0006366;transcription from RNA polymerase II promoter;4.14602400024419e-07!GO:0005773;vacuole;4.68626196221532e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.84670953032088e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.84670953032088e-07!GO:0008632;apoptotic program;4.87209255930958e-07!GO:0016469;proton-transporting two-sector ATPase complex;4.90588386251863e-07!GO:0048522;positive regulation of cellular process;5.34536066982762e-07!GO:0007005;mitochondrion organization and biogenesis;6.41048884751891e-07!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.43061389933985e-07!GO:0004812;aminoacyl-tRNA ligase activity;6.43061389933985e-07!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.43061389933985e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.63257983568342e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.63257983568342e-07!GO:0016567;protein ubiquitination;7.30247579041027e-07!GO:0019222;regulation of metabolic process;8.23414773587967e-07!GO:0048475;coated membrane;9.14235316853503e-07!GO:0030117;membrane coat;9.14235316853503e-07!GO:0009199;ribonucleoside triphosphate metabolic process;9.86940138978595e-07!GO:0009141;nucleoside triphosphate metabolic process;1.05389555708095e-06!GO:0000323;lytic vacuole;1.17167674947752e-06!GO:0005764;lysosome;1.17167674947752e-06!GO:0046034;ATP metabolic process;1.26813112718586e-06!GO:0030120;vesicle coat;1.31482502182277e-06!GO:0030662;coated vesicle membrane;1.31482502182277e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.32354089287759e-06!GO:0043038;amino acid activation;1.33876761973817e-06!GO:0006418;tRNA aminoacylation for protein translation;1.33876761973817e-06!GO:0043039;tRNA aminoacylation;1.33876761973817e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.34574086333374e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.34574086333374e-06!GO:0000245;spliceosome assembly;1.59497455623698e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.6263832901507e-06!GO:0015399;primary active transmembrane transporter activity;1.6263832901507e-06!GO:0019899;enzyme binding;1.70084964991217e-06!GO:0006461;protein complex assembly;1.74110328971203e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.80342316561357e-06!GO:0045259;proton-transporting ATP synthase complex;1.8684097995573e-06!GO:0005793;ER-Golgi intermediate compartment;2.21229150455993e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.59348319306745e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.75336913206549e-06!GO:0045786;negative regulation of progression through cell cycle;2.97425293082227e-06!GO:0004674;protein serine/threonine kinase activity;3.04394594516e-06!GO:0045333;cellular respiration;3.13065745652982e-06!GO:0003713;transcription coactivator activity;3.19344091395664e-06!GO:0005813;centrosome;4.30164899232928e-06!GO:0016563;transcription activator activity;4.5417391190313e-06!GO:0031324;negative regulation of cellular metabolic process;5.81270334373589e-06!GO:0000151;ubiquitin ligase complex;7.77434952322298e-06!GO:0005815;microtubule organizing center;7.94236876803069e-06!GO:0009108;coenzyme biosynthetic process;8.6967088138324e-06!GO:0006261;DNA-dependent DNA replication;8.6967088138324e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;9.38768927629274e-06!GO:0006613;cotranslational protein targeting to membrane;9.59100366382437e-06!GO:0015630;microtubule cytoskeleton;1.03328385591261e-05!GO:0006752;group transfer coenzyme metabolic process;1.19289570164719e-05!GO:0016564;transcription repressor activity;1.30527634570115e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.3200786394997e-05!GO:0005819;spindle;1.33124587704228e-05!GO:0005762;mitochondrial large ribosomal subunit;1.43995011229386e-05!GO:0000315;organellar large ribosomal subunit;1.43995011229386e-05!GO:0051168;nuclear export;1.50237833765309e-05!GO:0006099;tricarboxylic acid cycle;1.50237833765309e-05!GO:0046356;acetyl-CoA catabolic process;1.50237833765309e-05!GO:0006401;RNA catabolic process;1.50629648705767e-05!GO:0044431;Golgi apparatus part;1.55123211876687e-05!GO:0006310;DNA recombination;1.66866050535705e-05!GO:0006417;regulation of translation;1.88672825794184e-05!GO:0042110;T cell activation;2.26696642621175e-05!GO:0003724;RNA helicase activity;2.33121951706873e-05!GO:0000775;chromosome, pericentric region;2.59221240148231e-05!GO:0043492;ATPase activity, coupled to movement of substances;3.03888787434475e-05!GO:0044440;endosomal part;3.49133224671929e-05!GO:0010008;endosome membrane;3.49133224671929e-05!GO:0006084;acetyl-CoA metabolic process;3.52232031517823e-05!GO:0031323;regulation of cellular metabolic process;3.60066368107618e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;3.73102447578e-05!GO:0009892;negative regulation of metabolic process;3.73102447578e-05!GO:0000075;cell cycle checkpoint;3.73106997366176e-05!GO:0003690;double-stranded DNA binding;4.23499236046311e-05!GO:0005798;Golgi-associated vesicle;4.99197016053131e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;5.28327739519819e-05!GO:0006402;mRNA catabolic process;5.33529822364146e-05!GO:0005770;late endosome;5.44057375257189e-05!GO:0051329;interphase of mitotic cell cycle;5.67290342023207e-05!GO:0043623;cellular protein complex assembly;6.28740707236195e-05!GO:0050790;regulation of catalytic activity;6.55581228998321e-05!GO:0006612;protein targeting to membrane;7.01635723699528e-05!GO:0048518;positive regulation of biological process;7.56141973553872e-05!GO:0051325;interphase;7.75398608816655e-05!GO:0005657;replication fork;8.60130780574217e-05!GO:0009117;nucleotide metabolic process;8.60130780574217e-05!GO:0015992;proton transport;9.74777781461312e-05!GO:0009967;positive regulation of signal transduction;9.98949546600635e-05!GO:0005525;GTP binding;0.00010218289065378!GO:0006818;hydrogen transport;0.000104210167412781!GO:0051187;cofactor catabolic process;0.000106162342950442!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000121781707206072!GO:0009109;coenzyme catabolic process;0.000123016487919946!GO:0009615;response to virus;0.00013042312905753!GO:0007088;regulation of mitosis;0.000135933737415319!GO:0005885;Arp2/3 protein complex;0.000158780883289343!GO:0065007;biological regulation;0.000167559288667517!GO:0031326;regulation of cellular biosynthetic process;0.000168359847763095!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000185035379743069!GO:0016363;nuclear matrix;0.000224823512336681!GO:0003899;DNA-directed RNA polymerase activity;0.000237471311429018!GO:0008654;phospholipid biosynthetic process;0.000247636364343625!GO:0051427;hormone receptor binding;0.000263463462615234!GO:0005667;transcription factor complex;0.000265494597309339!GO:0030384;phosphoinositide metabolic process;0.000314001903097308!GO:0006352;transcription initiation;0.000332762563772005!GO:0008234;cysteine-type peptidase activity;0.00033824510615351!GO:0048468;cell development;0.000352270073762069!GO:0000314;organellar small ribosomal subunit;0.000358019435256665!GO:0005763;mitochondrial small ribosomal subunit;0.000358019435256665!GO:0008186;RNA-dependent ATPase activity;0.000385552026363653!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000428062626144112!GO:0003684;damaged DNA binding;0.000436032089146328!GO:0003924;GTPase activity;0.000441347896246042!GO:0043021;ribonucleoprotein binding;0.000454306925606088!GO:0008094;DNA-dependent ATPase activity;0.000457221086132134!GO:0006350;transcription;0.000478826610195777!GO:0000139;Golgi membrane;0.000503235876044607!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000503491422022111!GO:0008637;apoptotic mitochondrial changes;0.000505500442647154!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000528726373977314!GO:0035257;nuclear hormone receptor binding;0.000528901976825362!GO:0003729;mRNA binding;0.000536799709988221!GO:0005637;nuclear inner membrane;0.000586161725280106!GO:0006302;double-strand break repair;0.000598044083226425!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000622770208123138!GO:0005741;mitochondrial outer membrane;0.000626267835691214!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000658296939015565!GO:0016853;isomerase activity;0.000671147142406421!GO:0060090;molecular adaptor activity;0.000694288000300892!GO:0007006;mitochondrial membrane organization and biogenesis;0.000697245705919376!GO:0045454;cell redox homeostasis;0.000697462764885756!GO:0005769;early endosome;0.000714236137843493!GO:0016481;negative regulation of transcription;0.000818554868133155!GO:0015631;tubulin binding;0.000823667578117108!GO:0019867;outer membrane;0.000842278045094405!GO:0003678;DNA helicase activity;0.000870725760041218!GO:0051252;regulation of RNA metabolic process;0.00088391402252971!GO:0006891;intra-Golgi vesicle-mediated transport;0.000948155435228091!GO:0007051;spindle organization and biogenesis;0.0009689915509171!GO:0006414;translational elongation;0.000970966036767966!GO:0006289;nucleotide-excision repair;0.000970966036767966!GO:0006650;glycerophospholipid metabolic process;0.00100665011366604!GO:0016301;kinase activity;0.00101282831972714!GO:0000287;magnesium ion binding;0.00101970388487665!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00104062496540507!GO:0007264;small GTPase mediated signal transduction;0.00105709164784934!GO:0046489;phosphoinositide biosynthetic process;0.0010619105840971!GO:0004518;nuclease activity;0.00107410232799085!GO:0030658;transport vesicle membrane;0.00107581515212093!GO:0051090;regulation of transcription factor activity;0.00109925643633415!GO:0004004;ATP-dependent RNA helicase activity;0.0011037552567207!GO:0032561;guanyl ribonucleotide binding;0.00111105762848898!GO:0019001;guanyl nucleotide binding;0.00111105762848898!GO:0031968;organelle outer membrane;0.00112766586356063!GO:0019843;rRNA binding;0.00115469204095608!GO:0022890;inorganic cation transmembrane transporter activity;0.00116444176281801!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0012244445331163!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0012244445331163!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0012244445331163!GO:0006611;protein export from nucleus;0.00128709280729923!GO:0010468;regulation of gene expression;0.00132447145010326!GO:0043681;protein import into mitochondrion;0.00135109246052038!GO:0005774;vacuolar membrane;0.00156148607933346!GO:0030118;clathrin coat;0.0015814103409758!GO:0003714;transcription corepressor activity;0.00165184608278712!GO:0051092;activation of NF-kappaB transcription factor;0.00177013373970117!GO:0046649;lymphocyte activation;0.0017727058598551!GO:0009889;regulation of biosynthetic process;0.00178908539055369!GO:0048500;signal recognition particle;0.0018931939609153!GO:0000776;kinetochore;0.0019438110381015!GO:0008624;induction of apoptosis by extracellular signals;0.00209814833600541!GO:0051251;positive regulation of lymphocyte activation;0.00215512003911207!GO:0042802;identical protein binding;0.00220496435551576!GO:0019210;kinase inhibitor activity;0.00222278258859678!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00237104927498912!GO:0007093;mitotic cell cycle checkpoint;0.00251418713756923!GO:0046474;glycerophospholipid biosynthetic process;0.00251923318044702!GO:0031072;heat shock protein binding;0.00258436050074372!GO:0048471;perinuclear region of cytoplasm;0.00258981769313071!GO:0000082;G1/S transition of mitotic cell cycle;0.00260695409021258!GO:0051249;regulation of lymphocyte activation;0.00264208639551223!GO:0004860;protein kinase inhibitor activity;0.00270489469316655!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00270489469316655!GO:0005048;signal sequence binding;0.0027147376121865!GO:0005765;lysosomal membrane;0.0027147376121865!GO:0006383;transcription from RNA polymerase III promoter;0.00274224059369882!GO:0050865;regulation of cell activation;0.00274382618632138!GO:0019955;cytokine binding;0.00274382618632138!GO:0032259;methylation;0.00275044722269446!GO:0001836;release of cytochrome c from mitochondria;0.00277065894602753!GO:0008033;tRNA processing;0.0028129227650303!GO:0031982;vesicle;0.00284652175400558!GO:0051223;regulation of protein transport;0.00298180899391395!GO:0030660;Golgi-associated vesicle membrane;0.00306350554551086!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00307771914074664!GO:0050863;regulation of T cell activation;0.00314882523092534!GO:0043414;biopolymer methylation;0.00315359440060707!GO:0005684;U2-dependent spliceosome;0.00325766103724864!GO:0016741;transferase activity, transferring one-carbon groups;0.00326758817963586!GO:0008168;methyltransferase activity;0.00329154509287199!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00340052573808434!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00340052573808434!GO:0051052;regulation of DNA metabolic process;0.00340052573808434!GO:0022415;viral reproductive process;0.00340052573808434!GO:0043488;regulation of mRNA stability;0.00340639994921582!GO:0043487;regulation of RNA stability;0.00340639994921582!GO:0046822;regulation of nucleocytoplasmic transport;0.00345466972316859!GO:0001772;immunological synapse;0.00346375823579082!GO:0006338;chromatin remodeling;0.00350114024980982!GO:0016251;general RNA polymerase II transcription factor activity;0.00352428063155706!GO:0006839;mitochondrial transport;0.00355628354988204!GO:0007059;chromosome segregation;0.0035823943073775!GO:0051920;peroxiredoxin activity;0.00361747225142195!GO:0051087;chaperone binding;0.00369538368138788!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00369799343479207!GO:0045047;protein targeting to ER;0.00369799343479207!GO:0016791;phosphoric monoester hydrolase activity;0.00373727630017415!GO:0016311;dephosphorylation;0.00374724110481397!GO:0044437;vacuolar part;0.00381027518618078!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00395976444824349!GO:0004527;exonuclease activity;0.00412621547728298!GO:0007265;Ras protein signal transduction;0.00423191434164809!GO:0006607;NLS-bearing substrate import into nucleus;0.00431871675796201!GO:0016197;endosome transport;0.00447836698498099!GO:0008312;7S RNA binding;0.00460599133340134!GO:0005070;SH3/SH2 adaptor activity;0.00487649082258629!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00527269034958483!GO:0051336;regulation of hydrolase activity;0.00532042628474357!GO:0047485;protein N-terminus binding;0.00538987750286881!GO:0030518;steroid hormone receptor signaling pathway;0.00541015137391229!GO:0009165;nucleotide biosynthetic process;0.00547785536931613!GO:0008022;protein C-terminus binding;0.00560316406294235!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00569478163133792!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00578337753247074!GO:0008270;zinc ion binding;0.00590057497622175!GO:0019901;protein kinase binding;0.00592230004759567!GO:0003682;chromatin binding;0.00592230004759567!GO:0016788;hydrolase activity, acting on ester bonds;0.00622264269451495!GO:0051789;response to protein stimulus;0.00624786555834848!GO:0006986;response to unfolded protein;0.00624786555834848!GO:0043281;regulation of caspase activity;0.00633613597091791!GO:0008047;enzyme activator activity;0.00655826983257433!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00658216721220063!GO:0015002;heme-copper terminal oxidase activity;0.00658216721220063!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00658216721220063!GO:0004129;cytochrome-c oxidase activity;0.00658216721220063!GO:0006091;generation of precursor metabolites and energy;0.00661486540746538!GO:0051059;NF-kappaB binding;0.00661486540746538!GO:0048487;beta-tubulin binding;0.0069798598159248!GO:0006284;base-excision repair;0.00703806878906167!GO:0046966;thyroid hormone receptor binding;0.00705741145300523!GO:0031410;cytoplasmic vesicle;0.00709963044205018!GO:0008139;nuclear localization sequence binding;0.00721355374747256!GO:0007050;cell cycle arrest;0.00758890126349937!GO:0031988;membrane-bound vesicle;0.00759203772082744!GO:0050870;positive regulation of T cell activation;0.00796655230853282!GO:0003746;translation elongation factor activity;0.0080570343950444!GO:0000228;nuclear chromosome;0.00808225515489903!GO:0031902;late endosome membrane;0.00811175080891873!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.00812415099781709!GO:0031124;mRNA 3'-end processing;0.00815201049422699!GO:0032508;DNA duplex unwinding;0.00820911307827485!GO:0032392;DNA geometric change;0.00820911307827485!GO:0006497;protein amino acid lipidation;0.00825272895205359!GO:0000049;tRNA binding;0.00826675287506568!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00842817430300542!GO:0018193;peptidyl-amino acid modification;0.00848674308387583!GO:0030880;RNA polymerase complex;0.00861646332067598!GO:0003711;transcription elongation regulator activity;0.00868048723407402!GO:0000209;protein polyubiquitination;0.00868048723407402!GO:0004177;aminopeptidase activity;0.00870710329426046!GO:0016584;nucleosome positioning;0.00873738809446873!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00873738809446873!GO:0006007;glucose catabolic process;0.00885674319757193!GO:0044452;nucleolar part;0.00892080370671474!GO:0019904;protein domain specific binding;0.00896318800766143!GO:0016605;PML body;0.0090686332985223!GO:0051098;regulation of binding;0.00928574327670051!GO:0006626;protein targeting to mitochondrion;0.00929411589563724!GO:0006405;RNA export from nucleus;0.00949843620267028!GO:0008017;microtubule binding;0.00955038933400942!GO:0046467;membrane lipid biosynthetic process;0.0097490584431747!GO:0045936;negative regulation of phosphate metabolic process;0.00997033923648992!GO:0016859;cis-trans isomerase activity;0.0101167132847771!GO:0045321;leukocyte activation;0.0101265997801064!GO:0042393;histone binding;0.0103350657154369!GO:0030119;AP-type membrane coat adaptor complex;0.0105581583947673!GO:0031252;leading edge;0.0106979745336111!GO:0007259;JAK-STAT cascade;0.0107501440948565!GO:0019900;kinase binding;0.010950403339075!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.010950403339075!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0109624419206695!GO:0019318;hexose metabolic process;0.0109874074863701!GO:0016272;prefoldin complex;0.0110140233056023!GO:0051235;maintenance of localization;0.0112111605422392!GO:0042770;DNA damage response, signal transduction;0.0113374072401175!GO:0043621;protein self-association;0.0114760377494339!GO:0006013;mannose metabolic process;0.0114774710749594!GO:0005996;monosaccharide metabolic process;0.0114774710749594!GO:0051881;regulation of mitochondrial membrane potential;0.0115721450680957!GO:0008629;induction of apoptosis by intracellular signals;0.0116819135900078!GO:0022411;cellular component disassembly;0.0117828963462911!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0119362718691455!GO:0051540;metal cluster binding;0.0121188963740643!GO:0051536;iron-sulfur cluster binding;0.0121188963740643!GO:0007040;lysosome organization and biogenesis;0.0121353047245953!GO:0005788;endoplasmic reticulum lumen;0.0121364121904896!GO:0030125;clathrin vesicle coat;0.0123607468225775!GO:0030665;clathrin coated vesicle membrane;0.0123607468225775!GO:0030663;COPI coated vesicle membrane;0.0127016150788711!GO:0030126;COPI vesicle coat;0.0127016150788711!GO:0009966;regulation of signal transduction;0.0127331631428136!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0128603821555716!GO:0033116;ER-Golgi intermediate compartment membrane;0.0128603821555716!GO:0003725;double-stranded RNA binding;0.0130132417551349!GO:0030131;clathrin adaptor complex;0.0130664705132248!GO:0016569;covalent chromatin modification;0.0135996044312419!GO:0030137;COPI-coated vesicle;0.0137065242684278!GO:0030522;intracellular receptor-mediated signaling pathway;0.0137966997192283!GO:0045076;regulation of interleukin-2 biosynthetic process;0.0138568297680928!GO:0006268;DNA unwinding during replication;0.0138568297680928!GO:0046426;negative regulation of JAK-STAT cascade;0.0142279487220129!GO:0043596;nuclear replication fork;0.0142279487220129!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0143218970073114!GO:0010257;NADH dehydrogenase complex assembly;0.0143218970073114!GO:0033108;mitochondrial respiratory chain complex assembly;0.0143218970073114!GO:0032940;secretion by cell;0.0144386838198375!GO:0006506;GPI anchor biosynthetic process;0.0145738106112028!GO:0016023;cytoplasmic membrane-bound vesicle;0.0148368836922067!GO:0032200;telomere organization and biogenesis;0.0149809065743883!GO:0000723;telomere maintenance;0.0149809065743883!GO:0032774;RNA biosynthetic process;0.0151873802399656!GO:0031625;ubiquitin protein ligase binding;0.0152551555413236!GO:0030217;T cell differentiation;0.0154481864594181!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.015562360238068!GO:0000428;DNA-directed RNA polymerase complex;0.015562360238068!GO:0045892;negative regulation of transcription, DNA-dependent;0.0155761074145261!GO:0004721;phosphoprotein phosphatase activity;0.0156505869025146!GO:0030127;COPII vesicle coat;0.0156681595425734!GO:0012507;ER to Golgi transport vesicle membrane;0.0156681595425734!GO:0000059;protein import into nucleus, docking;0.0159138338180803!GO:0040029;regulation of gene expression, epigenetic;0.0159580443095623!GO:0006595;polyamine metabolic process;0.0159640841009035!GO:0030132;clathrin coat of coated pit;0.015965470203438!GO:0006505;GPI anchor metabolic process;0.0159996107635169!GO:0030521;androgen receptor signaling pathway;0.0160286085686918!GO:0030867;rough endoplasmic reticulum membrane;0.0160728516375537!GO:0004003;ATP-dependent DNA helicase activity;0.0165008927121686!GO:0051539;4 iron, 4 sulfur cluster binding;0.0165297817930963!GO:0044438;microbody part;0.0169465159763408!GO:0044439;peroxisomal part;0.0169465159763408!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0171162290877136!GO:0007052;mitotic spindle organization and biogenesis;0.0171723633395688!GO:0006351;transcription, DNA-dependent;0.0171723633395688!GO:0030134;ER to Golgi transport vesicle;0.0172466772235!GO:0003677;DNA binding;0.0173166041297424!GO:0045045;secretory pathway;0.0173373315495067!GO:0005791;rough endoplasmic reticulum;0.0175669645774872!GO:0016860;intramolecular oxidoreductase activity;0.017685243459921!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0177700477865232!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.018008381922997!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.018008381922997!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.018008381922997!GO:0030176;integral to endoplasmic reticulum membrane;0.01808192286362!GO:0004722;protein serine/threonine phosphatase activity;0.018536302818811!GO:0006468;protein amino acid phosphorylation;0.0185467657827274!GO:0030133;transport vesicle;0.018598809194001!GO:0004532;exoribonuclease activity;0.018598809194001!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.018598809194001!GO:0030258;lipid modification;0.0188859856401976!GO:0042101;T cell receptor complex;0.0188859856401976!GO:0031123;RNA 3'-end processing;0.0189552225284898!GO:0008213;protein amino acid alkylation;0.0190353166529842!GO:0006479;protein amino acid methylation;0.0190353166529842!GO:0044454;nuclear chromosome part;0.01903552971591!GO:0051091;positive regulation of transcription factor activity;0.0193557657860904!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.019472953736318!GO:0000339;RNA cap binding;0.0198651887613556!GO:0015923;mannosidase activity;0.020086295128235!GO:0016570;histone modification;0.0205399847641506!GO:0045449;regulation of transcription;0.0205429885729791!GO:0004197;cysteine-type endopeptidase activity;0.0205429885729791!GO:0006376;mRNA splice site selection;0.0205630605633682!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0205630605633682!GO:0008408;3'-5' exonuclease activity;0.0205717118949185!GO:0006778;porphyrin metabolic process;0.0206412548896052!GO:0033013;tetrapyrrole metabolic process;0.0206412548896052!GO:0046483;heterocycle metabolic process;0.021192263831998!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.021203267024826!GO:0042326;negative regulation of phosphorylation;0.0213779669918514!GO:0030695;GTPase regulator activity;0.0214486073789005!GO:0046979;TAP2 binding;0.0215066926331815!GO:0046977;TAP binding;0.0215066926331815!GO:0046978;TAP1 binding;0.0215066926331815!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0219452552921367!GO:0005869;dynactin complex;0.0219810719199693!GO:0043022;ribosome binding;0.022415229076197!GO:0044262;cellular carbohydrate metabolic process;0.0224817804978005!GO:0006672;ceramide metabolic process;0.0224817804978005!GO:0006914;autophagy;0.0226032129720511!GO:0050811;GABA receptor binding;0.0226642920915708!GO:0007034;vacuolar transport;0.0226942692138598!GO:0046519;sphingoid metabolic process;0.0227330486682416!GO:0004576;oligosaccharyl transferase activity;0.0227330486682416!GO:0048002;antigen processing and presentation of peptide antigen;0.0227890452735882!GO:0007033;vacuole organization and biogenesis;0.0229056979082798!GO:0042158;lipoprotein biosynthetic process;0.0232428039119858!GO:0009124;nucleoside monophosphate biosynthetic process;0.0234192656831116!GO:0009123;nucleoside monophosphate metabolic process;0.0234192656831116!GO:0005669;transcription factor TFIID complex;0.0234343706527733!GO:0000792;heterochromatin;0.0236464145418194!GO:0006458;'de novo' protein folding;0.0237376413063355!GO:0051084;'de novo' posttranslational protein folding;0.0237376413063355!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0238317938962986!GO:0031903;microbody membrane;0.0247543265638964!GO:0005778;peroxisomal membrane;0.0247543265638964!GO:0019783;small conjugating protein-specific protease activity;0.0250605098838075!GO:0009116;nucleoside metabolic process;0.0250982976703904!GO:0006919;caspase activation;0.0251434504758183!GO:0019079;viral genome replication;0.0251774919723792!GO:0006950;response to stress;0.0251774919723792!GO:0002440;production of molecular mediator of immune response;0.0257255648935385!GO:0000922;spindle pole;0.0258572315824244!GO:0019976;interleukin-2 binding;0.026162983616846!GO:0004911;interleukin-2 receptor activity;0.026162983616846!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0263045337070706!GO:0046365;monosaccharide catabolic process;0.0268940629365091!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0268940629365091!GO:0004843;ubiquitin-specific protease activity;0.0272572230133567!GO:0043433;negative regulation of transcription factor activity;0.0274639200480138!GO:0042289;MHC class II protein binding;0.0277464731329565!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.028537769405615!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.028537769405615!GO:0006779;porphyrin biosynthetic process;0.028537769405615!GO:0033014;tetrapyrrole biosynthetic process;0.028537769405615!GO:0042094;interleukin-2 biosynthetic process;0.0286986363600729!GO:0051452;cellular pH reduction;0.0290139860981189!GO:0051453;regulation of cellular pH;0.0290139860981189!GO:0045851;pH reduction;0.0290139860981189!GO:0046983;protein dimerization activity;0.0290807312241769!GO:0000738;DNA catabolic process, exonucleolytic;0.0291532901677728!GO:0000910;cytokinesis;0.0291731532831688!GO:0051338;regulation of transferase activity;0.0291979598197414!GO:0008250;oligosaccharyl transferase complex;0.0291979598197414!GO:0008287;protein serine/threonine phosphatase complex;0.0296519008669753!GO:0008625;induction of apoptosis via death domain receptors;0.0296808787260313!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0299589899058014!GO:0030140;trans-Golgi network transport vesicle;0.0300320809810727!GO:0006378;mRNA polyadenylation;0.0300380982588974!GO:0009112;nucleobase metabolic process;0.0301135257374586!GO:0046982;protein heterodimerization activity;0.0302168382780324!GO:0006470;protein amino acid dephosphorylation;0.0302370125675038!GO:0051219;phosphoprotein binding;0.0306065519467021!GO:0035258;steroid hormone receptor binding;0.0306562928389065!GO:0008276;protein methyltransferase activity;0.0306596064872749!GO:0005031;tumor necrosis factor receptor activity;0.0308379640984278!GO:0005832;chaperonin-containing T-complex;0.0308742643392292!GO:0005876;spindle microtubule;0.031451118115046!GO:0005083;small GTPase regulator activity;0.0317414504149716!GO:0008320;protein transmembrane transporter activity;0.0317515197467639!GO:0043284;biopolymer biosynthetic process;0.0318957741507636!GO:0033673;negative regulation of kinase activity;0.0322220567367782!GO:0006469;negative regulation of protein kinase activity;0.0322220567367782!GO:0015980;energy derivation by oxidation of organic compounds;0.0328711468010137!GO:0000781;chromosome, telomeric region;0.0329173389296562!GO:0045185;maintenance of protein localization;0.0329991098926639!GO:0048524;positive regulation of viral reproduction;0.0332982895133146!GO:0042608;T cell receptor binding;0.0336609885077735!GO:0042168;heme metabolic process;0.0338108033361919!GO:0006518;peptide metabolic process;0.0338393501288151!GO:0006144;purine base metabolic process;0.0340045260416905!GO:0043549;regulation of kinase activity;0.0341159944627343!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0344353639989058!GO:0016763;transferase activity, transferring pentosyl groups;0.0345204424312119!GO:0000118;histone deacetylase complex;0.0348014637753455!GO:0005521;lamin binding;0.0352743229332786!GO:0045792;negative regulation of cell size;0.0356948642693633!GO:0002521;leukocyte differentiation;0.0356999213100336!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0358564128006572!GO:0016790;thiolester hydrolase activity;0.0359382332804816!GO:0005777;peroxisome;0.0362522243704481!GO:0042579;microbody;0.0362522243704481!GO:0001784;phosphotyrosine binding;0.0362527456170782!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0362527456170782!GO:0046164;alcohol catabolic process;0.0363634000410994!GO:0005784;translocon complex;0.0373205393873569!GO:0045309;protein phosphorylated amino acid binding;0.0376446220826909!GO:0008538;proteasome activator activity;0.0376885444313939!GO:0051348;negative regulation of transferase activity;0.037774734788811!GO:0000152;nuclear ubiquitin ligase complex;0.0384637783107875!GO:0004221;ubiquitin thiolesterase activity;0.0395039598732765!GO:0030833;regulation of actin filament polymerization;0.0396193935921069!GO:0005092;GDP-dissociation inhibitor activity;0.0396552823522981!GO:0017134;fibroblast growth factor binding;0.0396621503186551!GO:0022884;macromolecule transmembrane transporter activity;0.0400212212812686!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0400212212812686!GO:0030308;negative regulation of cell growth;0.0400765941893883!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0402402272645566!GO:0030041;actin filament polymerization;0.0402775594234952!GO:0002483;antigen processing and presentation of endogenous peptide antigen;0.0403705420068002!GO:0019885;antigen processing and presentation of endogenous peptide antigen via MHC class I;0.0403705420068002!GO:0022406;membrane docking;0.041036454954851!GO:0048278;vesicle docking;0.041036454954851!GO:0051287;NAD binding;0.0413312149387068!GO:0051051;negative regulation of transport;0.0414676222526828!GO:0019320;hexose catabolic process;0.0415914253401203!GO:0019058;viral infectious cycle;0.0423896892813948!GO:0030433;ER-associated protein catabolic process;0.0426866647681127!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0426866647681127!GO:0045603;positive regulation of endothelial cell differentiation;0.0426866647681127!GO:0009161;ribonucleoside monophosphate metabolic process;0.0428764692791605!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0428764692791605!GO:0006096;glycolysis;0.0430163467348091!GO:0002820;negative regulation of adaptive immune response;0.0433214434911031!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0433214434911031!GO:0032507;maintenance of cellular protein localization;0.0438880766623761!GO:0005874;microtubule;0.0442145535698118!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0454791126322175!GO:0046914;transition metal ion binding;0.0457331282530286!GO:0019220;regulation of phosphate metabolic process;0.0457475100976539!GO:0051174;regulation of phosphorus metabolic process;0.0457475100976539!GO:0006783;heme biosynthetic process;0.0458180589410704!GO:0005095;GTPase inhibitor activity;0.0458249420994493!GO:0002507;tolerance induction;0.0462748191978961!GO:0006904;vesicle docking during exocytosis;0.0464309312366932!GO:0004907;interleukin receptor activity;0.0468356323426752!GO:0006730;one-carbon compound metabolic process;0.0471260309221289!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.047430336847142!GO:0031647;regulation of protein stability;0.047430336847142!GO:0007021;tubulin folding;0.0475312233774999!GO:0043280;positive regulation of caspase activity;0.0476957461655077!GO:0045061;thymic T cell selection;0.0479368597257143!GO:0005652;nuclear lamina;0.0481123799302738!GO:0006596;polyamine biosynthetic process;0.0482111686609014!GO:0043601;nuclear replisome;0.0482732198183657!GO:0030894;replisome;0.0482732198183657!GO:0043028;caspase regulator activity;0.0485054043212114!GO:0016491;oxidoreductase activity;0.0489887141762177!GO:0005096;GTPase activator activity;0.0489887141762177!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0497457053431964
|sample_id=11916
|sample_note=
|sample_sex=male
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=blood
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|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11916-125G8;search_select_hide=table117:FF:11916-125G8
}}
}}

Latest revision as of 18:29, 4 June 2020

Name:CD4+CD25+CD45RA- memory regulatory T cells expanded, donor2
Species:Human (Homo sapiens)
Library ID:CNhs13811
Sample type:primary cells
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2, 3, 4, 5, 6, 7
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexmale
age23
cell typeT cell
cell lineNA
companyNA
collaborationMichael Rehli (University of Regensberg)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot number59-60
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005387
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs13811 CAGE DRX008182 DRR009054
Accession ID Hg19

Library idBAMCTSS
CNhs13811 DRZ000479 DRZ001864
Accession ID Hg38

Library idBAMCTSS
CNhs13811 DRZ011829 DRZ013214
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0.306
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis-0.0299
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0.0151
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.189
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
C118-cerebellum-parietal-occipital-medial-middle-frontal-insula0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0.0523
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13811

Jaspar motifP-value
MA0002.22.77628e-5
MA0003.10.897
MA0004.10.848
MA0006.10.737
MA0007.10.839
MA0009.10.349
MA0014.10.944
MA0017.10.0838
MA0018.20.999
MA0019.10.103
MA0024.10.479
MA0025.10.188
MA0027.10.764
MA0028.10.0016
MA0029.10.381
MA0030.10.307
MA0031.10.833
MA0035.20.167
MA0038.10.0278
MA0039.20.941
MA0040.10.339
MA0041.10.237
MA0042.10.47
MA0043.10.131
MA0046.10.071
MA0047.20.899
MA0048.10.89
MA0050.11.8144e-7
MA0051.10.0206
MA0052.10.0095
MA0055.10.865
MA0057.10.866
MA0058.10.756
MA0059.10.373
MA0060.10.24
MA0061.10.00829
MA0062.24.39736e-10
MA0065.20.0296
MA0066.10.295
MA0067.10.578
MA0068.10.385
MA0069.10.683
MA0070.10.46
MA0071.10.464
MA0072.10.691
MA0073.10.832
MA0074.10.864
MA0076.11.83922e-4
MA0077.10.0659
MA0078.10.704
MA0079.20.419
MA0080.25.21874e-10
MA0081.10.0795
MA0083.10.132
MA0084.10.803
MA0087.10.379
MA0088.10.164
MA0090.12.48428e-4
MA0091.10.868
MA0092.10.709
MA0093.10.945
MA0099.27.87188e-4
MA0100.10.854
MA0101.10.544
MA0102.20.255
MA0103.10.0271
MA0104.20.286
MA0105.14.59636e-7
MA0106.10.636
MA0107.10.961
MA0108.22.99292e-11
MA0111.10.0489
MA0112.20.0785
MA0113.10.703
MA0114.10.148
MA0115.10.463
MA0116.11.96678e-6
MA0117.10.801
MA0119.10.903
MA0122.10.94
MA0124.10.37
MA0125.10.364
MA0131.10.457
MA0135.10.0872
MA0136.16.81159e-17
MA0137.20.391
MA0138.20.213
MA0139.10.0246
MA0140.10.386
MA0141.10.443
MA0142.10.629
MA0143.10.168
MA0144.10.383
MA0145.10.861
MA0146.10.0714
MA0147.10.255
MA0148.10.479
MA0149.10.0341
MA0150.10.892
MA0152.10.0386
MA0153.10.0702
MA0154.10.0132
MA0155.10.856
MA0156.11.10357e-11
MA0157.10.413
MA0159.10.227
MA0160.10.419
MA0162.10.518
MA0163.11.36512e-11
MA0164.10.821
MA0258.10.0253
MA0259.10.45



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13811

Novel motifP-value
10.0806
100.00715
1000.414
1010.0875
1020.455
1030.53
1040.807
1050.333
1060.223
1070.936
1080.864
1090.0359
110.0183
1100.37
1110.147
1120.111
1130.43
1140.113
1150.616
1160.316
1170.0023
1180.438
1190.316
120.601
1200.258
1210.563
1220.778
1231.69696e-6
1240.183
1250.954
1260.633
1270.411
1280.564
1290.331
130.308
1300.649
1310.811
1320.774
1330.131
1340.69
1350.651
1360.692
1370.0832
1380.218
1390.125
140.274
1400.127
1410.451
1420.7
1430.0109
1440.417
1450.121
1460.771
1470.105
1480.0262
1490.888
150.233
1500.506
1510.486
1520.716
1530.808
1540.473
1550.0361
1560.616
1570.186
1580.192
1590.77
160.506
1600.359
1610.0763
1620.327
1630.337
1640.0694
1650.312
1660.84
1670.228
1680.98
1690.108
170.692
180.554
190.751
20.992
200.594
210.166
220.866
230.955
240.857
250.183
260.0349
270.317
280.561
290.026
30.0267
300.0913
310.983
320.704
330.561
340.944
350.28
360.0141
370.139
380.526
390.759
40.917
400.217
410.692
420.0865
430.276
440.23
450.481
460.0588
470.00938
480.0324
490.0871
50.85
500.795
510.667
520.56
530.168
540.705
550.781
560.441
570.136
580.17
590.372
60.419
600.356
610.122
620.0844
630.36
640.14
650.547
660.779
670.949
680.958
690.798
70.327
700.0312
710.0347
720.0742
730.321
740.555
750.0258
760.279
770.964
780.044
790.939
80.342
800.304
810.245
820.05
830.56
840.0484
850.91
860.129
870.513
880.849
890.501
90.957
900.0601
910.36
920.363
930.459
940.17
950.013
960.0508
970.232
980.134
990.17



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs13811


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA

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