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MCL coexpression mm9:2386: Difference between revisions

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{{MCL_coexpression_mm9
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biosynthetic process;0.00361584397085411;74596!GO:0046341;CDP-diacylglycerol metabolic process;0.00361584397085411;74596!GO:0004605;phosphatidate cytidylyltransferase activity;0.00482099322332118;74596!GO:0006651;diacylglycerol biosynthetic process;0.0064269343952206;74596!GO:0046460;neutral lipid biosynthetic process;0.0064269343952206;74596!GO:0046463;acylglycerol biosynthetic process;0.0064269343952206;74596!GO:0046339;diacylglycerol metabolic process;0.0064269343952206;74596!GO:0046504;glycerol ether biosynthetic process;0.0064269343952206;74596!GO:0045017;glycerolipid biosynthetic process;0.0064269343952206;74596!GO:0001533;cornified envelope;0.0121947814690103;16447!GO:0030216;keratinocyte differentiation;0.0121947814690103;16447!GO:0006639;acylglycerol metabolic process;0.0121947814690103;74596!GO:0046486;glycerolipid metabolic process;0.0121947814690103;74596!GO:0006638;neutral lipid metabolic process;0.0121947814690103;74596!GO:0006662;glycerol ether metabolic 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|ontology_enrichment_uberon=UBERON:0000065!2.80e-07!41;UBERON:0000014!5.45e-07!5;UBERON:0001003!5.45e-07!5;UBERON:0002097!5.45e-07!5;UBERON:0002199!5.45e-07!5;UBERON:0007029!5.45e-07!5;UBERON:0007376!5.45e-07!5;UBERON:0002416!5.45e-07!5;UBERON:0007383!5.45e-07!5;UBERON:0001004!6.03e-07!42
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}}

Latest revision as of 18:27, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr3:92377648..92377664,-p1@Ivl
Mm9::chr3:92377667..92377678,-p2@Ivl
Mm9::chr3:92377789..92377793,-p3@Ivl
Mm9::chr5:102193870..102193883,+p7@Cds1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016024CDP-diacylglycerol biosynthetic process0.00361584397085411
GO:0046341CDP-diacylglycerol metabolic process0.00361584397085411
GO:0004605phosphatidate cytidylyltransferase activity0.00482099322332118
GO:0006651diacylglycerol biosynthetic process0.0064269343952206
GO:0046460neutral lipid biosynthetic process0.0064269343952206
GO:0046463acylglycerol biosynthetic process0.0064269343952206
GO:0046339diacylglycerol metabolic process0.0064269343952206
GO:0046504glycerol ether biosynthetic process0.0064269343952206
GO:0045017glycerolipid biosynthetic process0.0064269343952206
GO:0001533cornified envelope0.0121947814690103
GO:0030216keratinocyte differentiation0.0121947814690103
GO:0006639acylglycerol metabolic process0.0121947814690103
GO:0046486glycerolipid metabolic process0.0121947814690103
GO:0006638neutral lipid metabolic process0.0121947814690103
GO:0006662glycerol ether metabolic process0.0121947814690103
GO:0031424keratinization0.0121947814690103
GO:0009913epidermal cell differentiation0.0148749018209019
GO:0048730epidermis morphogenesis0.0196603756735073
GO:0008654phospholipid biosynthetic process0.022041208409552
GO:0046467membrane lipid biosynthetic process0.025775100156972
GO:0048729tissue morphogenesis0.025775100156972
GO:0008544epidermis development0.0314743322299509
GO:0007398ectoderm development0.0316695480076329
GO:0016779nucleotidyltransferase activity0.0318480830814946
GO:0006644phospholipid metabolic process0.0334493223003014
GO:0006643membrane lipid metabolic process0.0418268369940089



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
respiratory tract2.80e-0741
zone of skin5.45e-075
skin epidermis5.45e-075
skin of body5.45e-075
integument5.45e-075
surface5.45e-075
outer epithelium5.45e-075
integumental system5.45e-075
enveloping layer of ectoderm5.45e-075
respiratory system6.03e-0742


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.600426
MA0004.10.6888
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.10.581929
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.266382
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.396346
MA0056.10
MA0057.10.251896
MA0058.10.581673
MA0059.10.59559
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.12.03055
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.11.0551
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.201215
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.10.519148
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.10.605676
MA0103.10.540576
MA0105.10.313353
MA0106.10.899777
MA0107.10.533522
MA0108.22.26367
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.10.606338
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.11.91256
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.12.05562
MA0144.10.439506
MA0145.11.14526
MA0146.10.0944145
MA0147.10.453952
MA0148.10.706718
MA0149.10.611881
MA0062.20.319836
MA0035.20.788288
MA0039.20.238019
MA0138.20.951653
MA0002.20.368961
MA0137.20.559766
MA0104.20.386166
MA0047.20.845655
MA0112.20.211985
MA0065.20.212467
MA0150.11.61189
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.728853
MA0155.10.650923
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.10.10667
MA0163.10.672192
MA0164.10.817786
MA0080.21.32296
MA0018.20.828253
MA0099.22.17387
MA0079.20.000201415
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10
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