Novel motif:95

name:	motif95_AGCGAGCTAGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0033058	directional locomotion	7.809214e-10
GO:2000209	regulation of anoikis	6.531413e-9
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.778711e-8
GO:0042696	menarche	2.592152e-8
GO:0021759	globus pallidus development	2.721691e-8
GO:0060430	lung saccule development	4.415573e-8
GO:0097039	protein linear polyubiquitination	6.366894e-8
GO:0042538	hyperosmotic salinity response	1.770010e-7
GO:0010172	embryonic body morphogenesis	2.010459e-7
GO:0051365	cellular response to potassium ion starvation	5.606264e-7
GO:0006348	chromatin silencing at telomere	6.362752e-7
GO:0003108	negative regulation of the force of heart contraction by chemical signal	8.438815e-7
GO:0061084	negative regulation of protein refolding	1.286194e-6
GO:0006284	base-excision repair	1.599429e-6
GO:0031848	protection from non-homologous end joining at telomere	1.857533e-6
GO:0021986	habenula development	2.171918e-6
GO:0030262	apoptotic nuclear change	2.498104e-6
GO:0031627	telomeric loop formation	3.073622e-6
GO:0001774	microglial cell activation	3.556106e-6
GO:0060004	reflex	4.168960e-6
GO:2000210	positive regulation of anoikis	4.266174e-6
GO:0021892	cerebral cortex GABAergic interneuron differentiation	5.074060e-6
GO:0031442	positive regulation of mRNA 3'-end processing	5.663767e-6
GO:0021506	anterior neuropore closure	6.093758e-6
GO:0033083	regulation of immature T cell proliferation	6.385618e-6
GO:0090305	nucleic acid phosphodiester bond hydrolysis	7.781863e-6
GO:0021895	cerebral cortex neuron differentiation	8.706485e-6
GO:0046599	regulation of centriole replication	8.720106e-6
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	9.293691e-6
GO:0033088	negative regulation of immature T cell proliferation in thymus	1.176134e-5
GO:0006353	transcription termination, DNA-dependent	1.177359e-5
GO:0006308	DNA catabolic process	1.194716e-5
GO:0060484	lung-associated mesenchyme development	1.449192e-5
GO:0072203	cell proliferation involved in metanephros development	1.657840e-5
GO:0006105	succinate metabolic process	1.702663e-5
GO:0018993	somatic sex determination	1.874896e-5
GO:0006370	mRNA capping	2.076708e-5
GO:0006208	pyrimidine base catabolic process	2.242810e-5
GO:0006356	regulation of transcription from RNA polymerase I promoter	2.245022e-5
GO:0071105	response to interleukin-11	2.266511e-5
GO:0023035	CD40 signaling pathway	2.266511e-5
GO:0009304	tRNA transcription	2.442715e-5
GO:0043543	protein acylation	2.575727e-5
GO:0042335	cuticle development	2.704348e-5
GO:0048808	male genitalia morphogenesis	2.740763e-5
GO:0021513	spinal cord dorsal/ventral patterning	2.777133e-5
GO:0010509	polyamine homeostasis	2.923447e-5
GO:0006363	termination of RNA polymerase I transcription	3.164263e-5
GO:0043973	histone H3-K4 acetylation	3.457829e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.457829e-5
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.457829e-5
GO:0051647	nucleus localization	3.699963e-5
GO:0006538	glutamate catabolic process	3.743069e-5
GO:0046604	positive regulation of mitotic centrosome separation	3.820394e-5
GO:0043923	positive regulation by host of viral transcription	3.953435e-5
GO:0018283	iron incorporation into metallo-sulfur cluster	4.102011e-5
GO:0033108	mitochondrial respiratory chain complex assembly	4.274472e-5
GO:0033084	regulation of immature T cell proliferation in thymus	4.350508e-5
GO:0048339	paraxial mesoderm development	4.765794e-5
GO:0046605	regulation of centrosome cycle	4.778844e-5
GO:0014040	positive regulation of Schwann cell differentiation	4.780599e-5
GO:0015789	UDP-N-acetylgalactosamine transport	4.805709e-5
GO:0015787	UDP-glucuronic acid transport	4.805709e-5
GO:0018393	internal peptidyl-lysine acetylation	5.296787e-5
GO:0018394	peptidyl-lysine acetylation	5.485352e-5
GO:0035026	leading edge cell differentiation	5.621695e-5
GO:0051584	regulation of dopamine uptake	5.871243e-5
GO:0070170	regulation of tooth mineralization	6.656520e-5
GO:0006289	nucleotide-excision repair	6.729853e-5
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	7.605516e-5
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	7.605516e-5
GO:0048291	isotype switching to IgG isotypes	8.105519e-5
GO:0006844	acyl carnitine transport	8.105519e-5
GO:0050883	musculoskeletal movement, spinal reflex action	8.105519e-5
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	8.105519e-5
GO:0002368	B cell cytokine production	8.105519e-5
GO:0006473	protein acetylation	8.273694e-5
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	8.756227e-5
GO:0043149	stress fiber assembly	9.019574e-5
GO:0021877	forebrain neuron fate commitment	9.086893e-5
GO:0050685	positive regulation of mRNA processing	9.188960e-5
GO:0042797	tRNA transcription from RNA polymerase III promoter	9.635193e-5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	9.635193e-5
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	9.647833e-5
GO:0009452	RNA capping	9.662504e-5
GO:0016573	histone acetylation	9.958087e-5
GO:0000114	regulation of transcription involved in G1 phase of mitotic cell cycle	1.043175e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	1.148793e-4
GO:0046113	nucleobase catabolic process	1.166262e-4
GO:0032981	mitochondrial respiratory chain complex I assembly	1.267011e-4
GO:0016570	histone modification	1.278879e-4
GO:0033590	response to cobalamin	1.294953e-4
GO:0006117	acetaldehyde metabolic process	1.294953e-4
GO:0048148	behavioral response to cocaine	1.313129e-4
GO:0006379	mRNA cleavage	1.390539e-4
GO:0060596	mammary placode formation	1.410852e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.442311e-4
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.525878e-4
GO:0031860	telomeric 3' overhang formation	1.572937e-4
GO:0002031	G-protein coupled receptor internalization	1.626944e-4
GO:0048733	sebaceous gland development	1.665858e-4
GO:0043921	modulation by host of viral transcription	1.691563e-4
GO:0048663	neuron fate commitment	1.696899e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	1.842598e-4
GO:0031440	regulation of mRNA 3'-end processing	1.871450e-4
GO:0021623	oculomotor nerve formation	1.927263e-4
GO:0003404	optic vesicle morphogenesis	1.927263e-4
GO:0003409	optic cup structural organization	1.927263e-4
GO:0007217	tachykinin receptor signaling pathway	1.997862e-4
GO:0050434	positive regulation of viral transcription	2.021618e-4
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	2.038355e-4
GO:0016233	telomere capping	2.156149e-4
GO:0033262	regulation of DNA replication involved in S phase	2.174680e-4
GO:0003140	determination of left/right asymmetry in lateral mesoderm	2.189059e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	2.209097e-4
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.312641e-4
GO:0018205	peptidyl-lysine modification	2.358771e-4
GO:0021511	spinal cord patterning	2.378000e-4
GO:0045647	negative regulation of erythrocyte differentiation	2.442459e-4
GO:0008033	tRNA processing	2.462924e-4
GO:0035308	negative regulation of protein dephosphorylation	2.567586e-4
GO:0035725	sodium ion transmembrane transport	2.601057e-4
GO:0072111	cell proliferation involved in kidney development	2.612840e-4
GO:0016569	covalent chromatin modification	2.613126e-4
GO:0042699	follicle-stimulating hormone signaling pathway	2.616579e-4
GO:0010452	histone H3-K36 methylation	2.616579e-4
GO:0070845	polyubiquitinated misfolded protein transport	2.662735e-4
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	2.693018e-4
GO:0000731	DNA synthesis involved in DNA repair	2.760633e-4
GO:0060178	regulation of exocyst localization	2.830188e-4
GO:0061157	mRNA destabilization	2.830188e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	2.830188e-4
GO:0001928	regulation of exocyst assembly	2.830188e-4
GO:0006475	internal protein amino acid acetylation	2.873574e-4
GO:0071542	dopaminergic neuron differentiation	3.016596e-4
GO:0006540	glutamate decarboxylation to succinate	3.162618e-4
GO:0072093	metanephric renal vesicle formation	3.268864e-4
GO:0006369	termination of RNA polymerase II transcription	3.295501e-4
GO:0006405	RNA export from nucleus	3.496279e-4
GO:0006283	transcription-coupled nucleotide-excision repair	3.519742e-4
GO:0002098	tRNA wobble uridine modification	3.521035e-4
GO:0034227	tRNA thio-modification	3.521035e-4
GO:0065002	intracellular protein transmembrane transport	3.855629e-4
GO:0032074	negative regulation of nuclease activity	3.883175e-4
GO:0022038	corpus callosum development	4.172165e-4
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	4.260047e-4
GO:0007418	ventral midline development	4.314968e-4
GO:0006406	mRNA export from nucleus	4.489186e-4
GO:0033627	cell adhesion mediated by integrin	4.771317e-4
GO:0006972	hyperosmotic response	4.851975e-4
GO:2000617	positive regulation of histone H3-K9 acetylation	4.863640e-4
GO:2000620	positive regulation of histone H4-K16 acetylation	4.863640e-4
GO:0070512	positive regulation of histone H4-K20 methylation	4.863640e-4
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	4.863640e-4
GO:0043400	cortisol secretion	4.938651e-4
GO:0070179	D-serine biosynthetic process	4.938651e-4
GO:0010571	positive regulation of DNA replication involved in S phase	4.938651e-4
GO:0042703	menstruation	5.096315e-4
GO:0019101	female somatic sex determination	5.096315e-4
GO:0032092	positive regulation of protein binding	5.167075e-4
GO:0046782	regulation of viral transcription	5.182672e-4
GO:0090239	regulation of histone H4 acetylation	5.230931e-4
GO:0043280	positive regulation of caspase activity	5.495666e-4
GO:0007626	locomotory behavior	5.502037e-4
GO:0006612	protein targeting to membrane	5.648230e-4
GO:0007228	positive regulation of hh target transcription factor activity	6.168534e-4
GO:0006206	pyrimidine base metabolic process	6.600930e-4
GO:0071281	cellular response to iron ion	6.733244e-4
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	6.821057e-4
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	6.821057e-4
GO:0030539	male genitalia development	6.849666e-4
GO:0043922	negative regulation by host of viral transcription	6.906940e-4
GO:0046607	positive regulation of centrosome cycle	6.934571e-4
GO:0070172	positive regulation of tooth mineralization	6.975532e-4
GO:0035304	regulation of protein dephosphorylation	7.100215e-4
GO:0070194	synaptonemal complex disassembly	7.469270e-4
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	7.469270e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	7.577557e-4
GO:0071421	manganese ion transmembrane transport	7.577557e-4
GO:0060347	heart trabecula formation	7.621159e-4
GO:0006119	oxidative phosphorylation	7.623075e-4
GO:0003334	keratinocyte development	7.726721e-4
GO:0016539	intein-mediated protein splicing	7.751334e-4
GO:0006921	cellular component disassembly involved in apoptosis	7.976232e-4
GO:0030046	parallel actin filament bundle assembly	8.232592e-4
GO:0000022	mitotic spindle elongation	8.232592e-4
GO:0006360	transcription from RNA polymerase I promoter	8.297787e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	8.383045e-4
GO:0016926	protein desumoylation	8.670830e-4
GO:0046600	negative regulation of centriole replication	9.172857e-4
GO:0001842	neural fold formation	9.696939e-4
GO:0006359	regulation of transcription from RNA polymerase III promoter	9.961999e-4
GO:0043576	regulation of respiratory gaseous exchange	1.033394e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	1.062621e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	1.062621e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	1.062621e-3
GO:0009236	cobalamin biosynthetic process	1.062621e-3
GO:0007371	ventral midline determination	1.062621e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	1.117091e-3
GO:0035306	positive regulation of dephosphorylation	1.120902e-3
GO:0061384	heart trabecular morphogenesis	1.141252e-3
GO:0071104	response to interleukin-9	1.161283e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	1.177734e-3
GO:0090324	negative regulation of oxidative phosphorylation	1.181882e-3
GO:0010255	glucose mediated signaling pathway	1.181882e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.181882e-3
GO:0019264	glycine biosynthetic process from serine	1.222480e-3
GO:0045819	positive regulation of glycogen catabolic process	1.248701e-3
GO:0006919	activation of caspase activity	1.256031e-3
GO:0060482	lobar bronchus development	1.264340e-3
GO:0035307	positive regulation of protein dephosphorylation	1.267520e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	1.269833e-3
GO:0022027	interkinetic nuclear migration	1.288717e-3
GO:0021559	trigeminal nerve development	1.294644e-3
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	1.301253e-3
GO:0070875	positive regulation of glycogen metabolic process	1.305809e-3
GO:0034470	ncRNA processing	1.344252e-3
GO:0060486	Clara cell differentiation	1.438139e-3
GO:0061056	sclerotome development	1.439806e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.447427e-3
GO:0010225	response to UV-C	1.457379e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	1.474737e-3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	1.496655e-3
GO:0022417	protein maturation by protein folding	1.514938e-3
GO:0002074	extraocular skeletal muscle development	1.565456e-3
GO:0018202	peptidyl-histidine modification	1.595927e-3
GO:0090224	regulation of spindle organization	1.602369e-3
GO:2000465	regulation of glycogen (starch) synthase activity	1.621288e-3
GO:0021798	forebrain dorsal/ventral pattern formation	1.622695e-3
GO:0045078	positive regulation of interferon-gamma biosynthetic process	1.627019e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.653693e-3
GO:0014038	regulation of Schwann cell differentiation	1.653693e-3
GO:0060764	cell-cell signaling involved in mammary gland development	1.714259e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	1.714259e-3
GO:0009589	detection of UV	1.714259e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.714259e-3
GO:0070534	protein K63-linked ubiquitination	1.737206e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	1.750752e-3
GO:0060438	trachea development	1.772505e-3
GO:0030309	poly-N-acetyllactosamine metabolic process	1.844378e-3
GO:0050919	negative chemotaxis	1.898123e-3
GO:0021954	central nervous system neuron development	1.931881e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	1.952339e-3
GO:0046602	regulation of mitotic centrosome separation	1.954146e-3
GO:0060685	regulation of prostatic bud formation	1.994549e-3
GO:0030238	male sex determination	2.082452e-3
GO:0071545	inositol phosphate catabolic process	2.083428e-3
GO:0010952	positive regulation of peptidase activity	2.116779e-3
GO:0070918	production of small RNA involved in gene silencing by RNA	2.149431e-3
GO:0035425	autocrine signaling	2.167916e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	2.242964e-3
GO:0001302	replicative cell aging	2.307112e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	2.309340e-3
GO:0021952	central nervous system projection neuron axonogenesis	2.314191e-3
GO:0051851	modification by host of symbiont morphology or physiology	2.323139e-3
GO:0048368	lateral mesoderm development	2.347406e-3
GO:0030237	female sex determination	2.394690e-3
GO:0021955	central nervous system neuron axonogenesis	2.401781e-3
GO:0060167	regulation of adenosine receptor signaling pathway	2.495875e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	2.495875e-3
GO:0070193	synaptonemal complex organization	2.496136e-3
GO:0030718	germ-line stem cell maintenance	2.534183e-3
GO:0048343	paraxial mesodermal cell fate commitment	2.550138e-3
GO:0010824	regulation of centrosome duplication	2.592169e-3
GO:0035305	negative regulation of dephosphorylation	2.592169e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	2.642659e-3
GO:0046621	negative regulation of organ growth	2.658329e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	2.683585e-3
GO:0018924	mandelate metabolic process	2.801898e-3
GO:0018105	peptidyl-serine phosphorylation	2.838753e-3
GO:0046092	deoxycytidine metabolic process	2.850780e-3
GO:0034241	positive regulation of macrophage fusion	2.850780e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	2.850780e-3
GO:0007100	mitotic centrosome separation	2.850780e-3
GO:2000009	negative regulation of protein localization at cell surface	2.873275e-3
GO:0043456	regulation of pentose-phosphate shunt	2.873275e-3
GO:0046984	regulation of hemoglobin biosynthetic process	2.954521e-3
GO:0060580	ventral spinal cord interneuron fate determination	2.954521e-3
GO:0006409	tRNA export from nucleus	2.954521e-3
GO:0003327	type B pancreatic cell fate commitment	2.954521e-3
GO:0002282	microglial cell activation involved in immune response	3.018505e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3.043006e-3
GO:0042551	neuron maturation	3.079750e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	3.089755e-3
GO:0055089	fatty acid homeostasis	3.089755e-3
GO:0032536	regulation of cell projection size	3.133678e-3
GO:0050872	white fat cell differentiation	3.159722e-3
GO:0048524	positive regulation of viral reproduction	3.212610e-3
GO:0008344	adult locomotory behavior	3.225210e-3
GO:0050432	catecholamine secretion	3.287021e-3
GO:0015801	aromatic amino acid transport	3.403302e-3
GO:0021603	cranial nerve formation	3.438343e-3
GO:0034776	response to histamine	3.538031e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	3.538031e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	3.538031e-3
GO:0016046	detection of fungus	3.538031e-3
GO:0006313	transposition, DNA-mediated	3.538031e-3
GO:0045905	positive regulation of translational termination	3.558507e-3
GO:0045901	positive regulation of translational elongation	3.558507e-3
GO:0006452	translational frameshifting	3.558507e-3
GO:0044154	histone H3-K14 acetylation	3.558507e-3
GO:0060579	ventral spinal cord interneuron fate commitment	3.584173e-3
GO:0040023	establishment of nucleus localization	3.649103e-3
GO:0009262	deoxyribonucleotide metabolic process	3.687515e-3
GO:0070873	regulation of glycogen metabolic process	3.754239e-3
GO:0071359	cellular response to dsRNA	3.782662e-3
GO:0006610	ribosomal protein import into nucleus	3.793687e-3
GO:0050775	positive regulation of dendrite morphogenesis	3.834144e-3
GO:0072236	metanephric loop of Henle development	3.834929e-3
GO:0008635	activation of caspase activity by cytochrome c	3.905299e-3
GO:0072011	glomerular endothelium development	3.949943e-3
GO:0072144	glomerular mesangial cell development	3.949943e-3
GO:0071206	establishment of protein localization to juxtaparanode region of axon	3.949943e-3
GO:0060168	positive regulation of adenosine receptor signaling pathway	3.949943e-3
GO:0003151	outflow tract morphogenesis	3.985584e-3
GO:0043314	negative regulation of neutrophil degranulation	4.064205e-3
GO:0009264	deoxyribonucleotide catabolic process	4.075245e-3
GO:0021979	hypothalamus cell differentiation	4.108627e-3
GO:0015742	alpha-ketoglutarate transport	4.115555e-3
GO:0032897	negative regulation of viral transcription	4.207798e-3
GO:0045047	protein targeting to ER	4.238210e-3
GO:0060013	righting reflex	4.273611e-3
GO:0021853	cerebral cortex GABAergic interneuron migration	4.273611e-3
GO:0045200	establishment of neuroblast polarity	4.288433e-3
GO:0043048	dolichyl monophosphate biosynthetic process	4.288433e-3
GO:0002082	regulation of oxidative phosphorylation	4.288433e-3
GO:0021819	layer formation in cerebral cortex	4.293182e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	4.314654e-3
GO:0042989	sequestering of actin monomers	4.318199e-3
GO:2000467	positive regulation of glycogen (starch) synthase activity	4.500808e-3
GO:0002016	regulation of blood volume by renin-angiotensin	4.636272e-3
GO:0032929	negative regulation of superoxide anion generation	4.916574e-3
GO:0046501	protoporphyrinogen IX metabolic process	4.916574e-3
GO:0072092	ureteric bud invasion	4.949287e-3
GO:0006545	glycine biosynthetic process	5.001834e-3
GO:0051532	regulation of NFAT protein import into nucleus	5.015582e-3
GO:0031297	replication fork processing	5.017978e-3
GO:0008589	regulation of smoothened signaling pathway	5.031545e-3
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	5.073211e-3
GO:0031017	exocrine pancreas development	5.073211e-3
GO:0071539	protein localization to centrosome	5.144734e-3
GO:0042417	dopamine metabolic process	5.158908e-3
GO:0006481	C-terminal protein methylation	5.189213e-3
GO:0021953	central nervous system neuron differentiation	5.233690e-3
GO:0043097	pyrimidine nucleoside salvage	5.551923e-3
GO:0043983	histone H4-K12 acetylation	5.553924e-3
GO:0060534	trachea cartilage development	5.582148e-3
GO:0070671	response to interleukin-12	5.638679e-3
GO:0043966	histone H3 acetylation	5.639387e-3
GO:0043174	nucleoside salvage	5.695427e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	5.769831e-3
GO:0048340	paraxial mesoderm morphogenesis	5.795395e-3
GO:0051292	nuclear pore complex assembly	5.802019e-3
GO:0051660	establishment of centrosome localization	5.802019e-3
GO:0048561	establishment of organ orientation	5.802019e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	5.802019e-3
GO:0021540	corpus callosum morphogenesis	5.802019e-3
GO:0042694	muscle cell fate specification	5.802019e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5.865592e-3
GO:0031133	regulation of axon diameter	5.888032e-3
GO:0010907	positive regulation of glucose metabolic process	5.896937e-3
GO:0014044	Schwann cell development	5.933233e-3
GO:0071897	DNA biosynthetic process	5.934083e-3
GO:0072143	mesangial cell development	6.010750e-3
GO:0043467	regulation of generation of precursor metabolites and energy	6.026247e-3
GO:0042780	tRNA 3'-end processing	6.045821e-3
GO:0006713	glucocorticoid catabolic process	6.045821e-3
GO:0035195	gene silencing by miRNA	6.119681e-3
GO:0010815	bradykinin catabolic process	6.126320e-3
GO:0051196	regulation of coenzyme metabolic process	6.129138e-3
GO:0060459	left lung development	6.130092e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	6.186420e-3
GO:0021879	forebrain neuron differentiation	6.272484e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	6.290889e-3
GO:0006563	L-serine metabolic process	6.325737e-3
GO:0010868	negative regulation of triglyceride biosynthetic process	6.341038e-3
GO:0048752	semicircular canal morphogenesis	6.508249e-3
GO:0046884	follicle-stimulating hormone secretion	6.635301e-3
GO:0032275	luteinizing hormone secretion	6.635301e-3
GO:0017004	cytochrome complex assembly	6.635301e-3
GO:0045875	negative regulation of sister chromatid cohesion	6.673766e-3
GO:0046620	regulation of organ growth	6.681454e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	6.709210e-3
GO:0035552	oxidative single-stranded DNA demethylation	6.709210e-3
GO:0048242	epinephrine secretion	6.709210e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	6.746699e-3
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	6.887948e-3
GO:0043538	regulation of actin phosphorylation	6.906865e-3
GO:0008052	sensory organ boundary specification	6.906865e-3
GO:0014813	satellite cell commitment	7.064197e-3
GO:0051573	negative regulation of histone H3-K9 methylation	7.082349e-3
GO:0048859	formation of anatomical boundary	7.082349e-3
GO:0006244	pyrimidine nucleotide catabolic process	7.082349e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	7.082349e-3
GO:0021843	substrate-independent telencephalic tangential interneuron migration	7.082349e-3
GO:0001710	mesodermal cell fate commitment	7.191383e-3
GO:0051205	protein insertion into membrane	7.216793e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	7.259094e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	7.278302e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	7.282205e-3
GO:0031129	inductive cell-cell signaling	7.288886e-3
GO:0061097	regulation of protein tyrosine kinase activity	7.321805e-3
GO:0035194	posttranscriptional gene silencing by RNA	7.386793e-3
GO:0048332	mesoderm morphogenesis	7.585973e-3
GO:0003057	regulation of the force of heart contraction by chemical signal	7.616124e-3
GO:0006352	transcription initiation, DNA-dependent	7.649938e-3
GO:0060359	response to ammonium ion	7.670080e-3
GO:0045217	cell-cell junction maintenance	7.714046e-3
GO:0035435	phosphate ion transmembrane transport	7.798168e-3
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	7.828084e-3
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	7.828084e-3
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	7.828084e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	7.828084e-3
GO:0007502	digestive tract mesoderm development	7.828084e-3
GO:0080125	multicellular structure septum development	7.828084e-3
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	7.828084e-3
GO:0035511	oxidative DNA demethylation	7.828084e-3
GO:0014858	positive regulation of skeletal muscle cell proliferation	7.828084e-3
GO:0072592	oxygen metabolic process	7.828084e-3
GO:0046534	positive regulation of photoreceptor cell differentiation	7.828084e-3
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	7.828084e-3
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	7.828084e-3
GO:0009151	purine deoxyribonucleotide metabolic process	7.900250e-3
GO:0050886	endocrine process	7.960960e-3
GO:0014816	satellite cell differentiation	7.983470e-3
GO:0070309	lens fiber cell morphogenesis	8.101117e-3
GO:0006654	phosphatidic acid biosynthetic process	8.101117e-3
GO:0051702	interaction with symbiont	8.209787e-3
GO:0035137	hindlimb morphogenesis	8.212551e-3
GO:0071294	cellular response to zinc ion	8.299481e-3
GO:0035356	cellular triglyceride homeostasis	8.515927e-3
GO:0021997	neural plate axis specification	8.548159e-3
GO:0035470	positive regulation of vascular wound healing	8.548159e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	8.682927e-3
GO:0009450	gamma-aminobutyric acid catabolic process	8.770932e-3
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	8.795647e-3
GO:0072529	pyrimidine-containing compound catabolic process	8.880513e-3
GO:0090303	positive regulation of wound healing	9.075297e-3
GO:0090230	regulation of centromere complex assembly	9.199566e-3
GO:0051318	G1 phase	9.235202e-3
GO:0003148	outflow tract septum morphogenesis	9.363401e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	9.382226e-3
GO:0043628	ncRNA 3'-end processing	9.487864e-3
GO:0019230	proprioception	9.523539e-3
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	9.571398e-3
GO:0034969	histone arginine methylation	9.647738e-3
GO:0021557	oculomotor nerve development	9.647738e-3
GO:0043967	histone H4 acetylation	9.688117e-3
GO:0045880	positive regulation of smoothened signaling pathway	1.000107e-2
GO:0070972	protein localization in endoplasmic reticulum	1.011731e-2
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.013219e-2
GO:0021871	forebrain regionalization	1.016188e-2
GO:0061099	negative regulation of protein tyrosine kinase activity	1.028671e-2
GO:0033692	cellular polysaccharide biosynthetic process	1.032824e-2
GO:0022011	myelination in peripheral nervous system	1.033394e-2
GO:0022601	menstrual cycle phase	1.036023e-2
GO:0051572	negative regulation of histone H3-K4 methylation	1.036535e-2
GO:0051567	histone H3-K9 methylation	1.036535e-2
GO:0016540	protein autoprocessing	1.036893e-2
GO:0007498	mesoderm development	1.042995e-2
GO:0014707	branchiomeric skeletal muscle development	1.047742e-2
GO:0048048	embryonic eye morphogenesis	1.059546e-2
GO:0043313	regulation of neutrophil degranulation	1.064073e-2
GO:2000773	negative regulation of cellular senescence	1.068943e-2
GO:0045039	protein import into mitochondrial inner membrane	1.068943e-2
GO:0006285	base-excision repair, AP site formation	1.068943e-2
GO:0043697	cell dedifferentiation	1.068943e-2
GO:0050779	RNA destabilization	1.069767e-2
GO:0019102	male somatic sex determination	1.071366e-2
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	1.071366e-2
GO:0045720	negative regulation of integrin biosynthetic process	1.071366e-2
GO:0060480	lung goblet cell differentiation	1.074509e-2
GO:0032707	negative regulation of interleukin-23 production	1.074509e-2
GO:0051725	protein de-ADP-ribosylation	1.074509e-2
GO:0010675	regulation of cellular carbohydrate metabolic process	1.080730e-2
GO:0003309	type B pancreatic cell differentiation	1.084693e-2
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.088558e-2
GO:0034971	histone H3-R17 methylation	1.088558e-2
GO:0032900	negative regulation of neurotrophin production	1.090976e-2
GO:2000370	positive regulation of clathrin-mediated endocytosis	1.090976e-2
GO:0010760	negative regulation of macrophage chemotaxis	1.090976e-2
GO:0032244	positive regulation of nucleoside transport	1.090976e-2
GO:0048814	regulation of dendrite morphogenesis	1.096002e-2
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	1.098766e-2
GO:0033566	gamma-tubulin complex localization	1.098766e-2
GO:0070256	negative regulation of mucus secretion	1.098766e-2
GO:0006384	transcription initiation from RNA polymerase III promoter	1.098766e-2
GO:0010722	regulation of ferrochelatase activity	1.098766e-2
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.098766e-2
GO:0010430	fatty acid omega-oxidation	1.098766e-2
GO:0007130	synaptonemal complex assembly	1.101259e-2
GO:0042473	outer ear morphogenesis	1.105300e-2
GO:0048488	synaptic vesicle endocytosis	1.106887e-2
GO:0060592	mammary gland formation	1.107368e-2
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.121840e-2
GO:0046134	pyrimidine nucleoside biosynthetic process	1.123229e-2
GO:0070544	histone H3-K36 demethylation	1.126489e-2
GO:0032225	regulation of synaptic transmission, dopaminergic	1.145056e-2
GO:0071472	cellular response to salt stress	1.148807e-2
GO:0034442	regulation of lipoprotein oxidation	1.148807e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010467	gene expression	6.717491e-10
GO:0090304	nucleic acid metabolic process	1.110372e-9
GO:0016070	RNA metabolic process	1.450240e-9
GO:0016072	rRNA metabolic process	5.941831e-9
GO:0006351	transcription, DNA-dependent	9.406280e-9
GO:0032774	RNA biosynthetic process	1.229146e-8
GO:0071422	succinate transmembrane transport	2.768741e-8
GO:0006139	nucleobase-containing compound metabolic process	2.858394e-8
GO:0070936	protein K48-linked ubiquitination	5.123335e-8
GO:0006364	rRNA processing	9.513938e-8
GO:0051252	regulation of RNA metabolic process	1.139211e-7
GO:0000154	rRNA modification	1.645688e-7
GO:0001579	medium-chain fatty acid transport	2.709436e-7
GO:0097022	lymphocyte migration into lymph node	3.057172e-7
GO:0072610	interleukin-12 secretion	3.057172e-7
GO:0010468	regulation of gene expression	3.284973e-7
GO:0031167	rRNA methylation	3.986902e-7
GO:0050775	positive regulation of dendrite morphogenesis	5.407371e-7
GO:0044260	cellular macromolecule metabolic process	6.091167e-7
GO:2000112	regulation of cellular macromolecule biosynthetic process	6.427430e-7
GO:0006355	regulation of transcription, DNA-dependent	6.685277e-7
GO:0097026	dendritic cell dendrite assembly	6.718713e-7
GO:0045084	positive regulation of interleukin-12 biosynthetic process	9.668338e-7
GO:0034645	cellular macromolecule biosynthetic process	1.073909e-6
GO:0009059	macromolecule biosynthetic process	1.282814e-6
GO:0030031	cell projection assembly	1.748677e-6
GO:0019219	regulation of nucleobase-containing compound metabolic process	2.355336e-6
GO:0010629	negative regulation of gene expression	3.497655e-6
GO:0070534	protein K63-linked ubiquitination	4.009649e-6
GO:0010556	regulation of macromolecule biosynthetic process	4.838100e-6
GO:0042760	very long-chain fatty acid catabolic process	5.759846e-6
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	5.807153e-6
GO:0010498	proteasomal protein catabolic process	7.992750e-6
GO:0000738	DNA catabolic process, exonucleolytic	8.472131e-6
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	8.760552e-6
GO:0006281	DNA repair	1.026395e-5
GO:0051583	dopamine uptake	1.038794e-5
GO:0031508	centromeric heterochromatin formation	1.050550e-5
GO:0051171	regulation of nitrogen compound metabolic process	1.052056e-5
GO:0034660	ncRNA metabolic process	1.109766e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.245606e-5
GO:0032119	sequestering of zinc ion	1.285364e-5
GO:0016568	chromatin modification	1.290787e-5
GO:0045948	positive regulation of translational initiation	1.336996e-5
GO:2000036	regulation of stem cell maintenance	1.410495e-5
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.646288e-5
GO:0060591	chondroblast differentiation	1.646288e-5
GO:0006325	chromatin organization	1.717049e-5
GO:0051099	positive regulation of binding	1.853314e-5
GO:0006434	seryl-tRNA aminoacylation	2.152589e-5
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.372566e-5
GO:2000412	positive regulation of thymocyte migration	2.586832e-5
GO:0002518	lymphocyte chemotaxis across high endothelial venule	2.586832e-5
GO:0042278	purine nucleoside metabolic process	2.760180e-5
GO:0010558	negative regulation of macromolecule biosynthetic process	2.786559e-5
GO:0001710	mesodermal cell fate commitment	2.865093e-5
GO:0051956	negative regulation of amino acid transport	2.920066e-5
GO:0032446	protein modification by small protein conjugation	2.974353e-5
GO:0045892	negative regulation of transcription, DNA-dependent	2.997863e-5
GO:0034695	response to prostaglandin E stimulus	3.152750e-5
GO:0009452	RNA capping	3.371935e-5
GO:0061084	negative regulation of protein refolding	3.687416e-5
GO:0045075	regulation of interleukin-12 biosynthetic process	3.696310e-5
GO:0051253	negative regulation of RNA metabolic process	3.784231e-5
GO:0034641	cellular nitrogen compound metabolic process	4.125499e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	4.127807e-5
GO:0045994	positive regulation of translational initiation by iron	4.127807e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	4.127807e-5
GO:0002037	negative regulation of L-glutamate transport	4.127807e-5
GO:0030866	cortical actin cytoskeleton organization	4.247302e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	4.294032e-5
GO:0033590	response to cobalamin	4.294032e-5
GO:0032092	positive regulation of protein binding	4.526301e-5
GO:0014826	vein smooth muscle contraction	4.729525e-5
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	4.973434e-5
GO:0002036	regulation of L-glutamate transport	5.216931e-5
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	5.270560e-5
GO:0016567	protein ubiquitination	5.512368e-5
GO:0045624	positive regulation of T-helper cell differentiation	5.757490e-5
GO:0038007	netrin-activated signaling pathway	6.555305e-5
GO:2000772	regulation of cellular senescence	6.567401e-5
GO:0051953	negative regulation of amine transport	6.624643e-5
GO:0071843	cellular component biogenesis at cellular level	6.646174e-5
GO:0030035	microspike assembly	6.699149e-5
GO:0031323	regulation of cellular metabolic process	6.988292e-5
GO:0015939	pantothenate metabolic process	7.238955e-5
GO:0043632	modification-dependent macromolecule catabolic process	7.479487e-5
GO:0006511	ubiquitin-dependent protein catabolic process	7.620401e-5
GO:0046452	dihydrofolate metabolic process	7.865151e-5
GO:0071105	response to interleukin-11	7.865151e-5
GO:0009119	ribonucleoside metabolic process	8.001729e-5
GO:0031128	developmental induction	8.067181e-5
GO:0031326	regulation of cellular biosynthetic process	8.246530e-5
GO:0046128	purine ribonucleoside metabolic process	8.419846e-5
GO:0007498	mesoderm development	8.726049e-5
GO:0031098	stress-activated protein kinase signaling cascade	8.830935e-5
GO:2000242	negative regulation of reproductive process	8.832867e-5
GO:0019941	modification-dependent protein catabolic process	9.324444e-5
GO:0046847	filopodium assembly	1.019488e-4
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.054629e-4
GO:0022613	ribonucleoprotein complex biogenesis	1.117650e-4
GO:0006346	methylation-dependent chromatin silencing	1.213972e-4
GO:0010605	negative regulation of macromolecule metabolic process	1.249027e-4
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	1.254695e-4
GO:0014040	positive regulation of Schwann cell differentiation	1.291776e-4
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.291776e-4
GO:0033088	negative regulation of immature T cell proliferation in thymus	1.310687e-4
GO:0031327	negative regulation of cellular biosynthetic process	1.331242e-4
GO:0051276	chromosome organization	1.350158e-4
GO:0035674	tricarboxylic acid transmembrane transport	1.408803e-4
GO:0071104	response to interleukin-9	1.408803e-4
GO:0031507	heterochromatin formation	1.453777e-4
GO:0045627	positive regulation of T-helper 1 cell differentiation	1.462473e-4
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.557460e-4
GO:0060235	lens induction in camera-type eye	1.598364e-4
GO:0042398	cellular modified amino acid biosynthetic process	1.625469e-4
GO:0030219	megakaryocyte differentiation	1.652528e-4
GO:0021549	cerebellum development	1.656680e-4
GO:0045905	positive regulation of translational termination	1.689457e-4
GO:0045901	positive regulation of translational elongation	1.689457e-4
GO:0006452	translational frameshifting	1.689457e-4
GO:0072093	metanephric renal vesicle formation	1.689524e-4
GO:0007254	JNK cascade	1.728146e-4
GO:0035195	gene silencing by miRNA	1.735582e-4
GO:0021983	pituitary gland development	1.846862e-4
GO:0048332	mesoderm morphogenesis	1.884009e-4
GO:0045168	cell-cell signaling involved in cell fate commitment	2.015035e-4
GO:0035725	sodium ion transmembrane transport	2.035090e-4
GO:0007141	male meiosis I	2.104168e-4
GO:0000729	DNA double-strand break processing	2.137891e-4
GO:0006807	nitrogen compound metabolic process	2.150843e-4
GO:0048333	mesodermal cell differentiation	2.304764e-4
GO:0051238	sequestering of metal ion	2.311475e-4
GO:0006556	S-adenosylmethionine biosynthetic process	2.311475e-4
GO:0032615	interleukin-12 production	2.311475e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.487293e-4
GO:0051603	proteolysis involved in cellular protein catabolic process	2.489918e-4
GO:0034470	ncRNA processing	2.505494e-4
GO:0009890	negative regulation of biosynthetic process	2.609946e-4
GO:0009116	nucleoside metabolic process	2.697816e-4
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2.755096e-4
GO:0043524	negative regulation of neuron apoptosis	3.010576e-4
GO:0042254	ribosome biogenesis	3.044410e-4
GO:0035269	protein O-linked mannosylation	3.114114e-4
GO:0035194	posttranscriptional gene silencing by RNA	3.253416e-4
GO:0071233	cellular response to leucine	3.366054e-4
GO:0010070	zygote asymmetric cell division	3.366054e-4
GO:0006391	transcription initiation from mitochondrial promoter	3.442311e-4
GO:0006986	response to unfolded protein	3.606942e-4
GO:0022037	metencephalon development	3.630494e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	3.695660e-4
GO:0071423	malate transmembrane transport	4.125133e-4
GO:2000682	positive regulation of rubidium ion transport	4.125133e-4
GO:0046491	L-methylmalonyl-CoA metabolic process	4.125133e-4
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	4.125133e-4
GO:0015709	thiosulfate transport	4.125133e-4
GO:0001682	tRNA 5'-leader removal	4.125133e-4
GO:0035826	rubidium ion transport	4.125133e-4
GO:0016078	tRNA catabolic process	4.125133e-4
GO:0032065	cortical protein anchoring	4.125133e-4
GO:0071281	cellular response to iron ion	4.298863e-4
GO:0046881	positive regulation of follicle-stimulating hormone secretion	4.347893e-4
GO:0009889	regulation of biosynthetic process	4.429898e-4
GO:0051254	positive regulation of RNA metabolic process	4.468445e-4
GO:2000774	positive regulation of cellular senescence	4.745116e-4
GO:0090402	oncogene-induced senescence	4.745116e-4
GO:0035986	senescence-associated heterochromatin focus formation	4.745116e-4
GO:0021696	cerebellar cortex morphogenesis	4.938489e-4
GO:0072124	regulation of glomerular mesangial cell proliferation	4.999660e-4
GO:0060216	definitive hemopoiesis	5.018852e-4
GO:0042473	outer ear morphogenesis	5.171738e-4
GO:0035645	enteric smooth muscle cell differentiation	5.258525e-4
GO:0007497	posterior midgut development	5.258525e-4
GO:0035553	oxidative single-stranded RNA demethylation	5.393389e-4
GO:0035461	vitamin transmembrane transport	5.393389e-4
GO:0035520	monoubiquitinated protein deubiquitination	5.393389e-4
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	5.457899e-4
GO:0034508	centromere complex assembly	5.496462e-4
GO:0070170	regulation of tooth mineralization	5.520492e-4
GO:0006449	regulation of translational termination	5.833679e-4
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	5.833679e-4
GO:0046500	S-adenosylmethionine metabolic process	5.871505e-4
GO:0070647	protein modification by small protein conjugation or removal	6.126973e-4
GO:0034661	ncRNA catabolic process	6.154771e-4
GO:0001672	regulation of chromatin assembly or disassembly	6.170388e-4
GO:0050901	leukocyte tethering or rolling	6.238800e-4
GO:0015746	citrate transport	6.398406e-4
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	6.559535e-4
GO:0015872	dopamine transport	6.559535e-4
GO:0001787	natural killer cell proliferation	6.592436e-4
GO:0010944	negative regulation of transcription by competitive promoter binding	6.656814e-4
GO:0060712	spongiotrophoblast layer development	6.924646e-4
GO:2000016	negative regulation of determination of dorsal identity	7.021696e-4
GO:0045893	positive regulation of transcription, DNA-dependent	7.395417e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	7.623305e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	7.674479e-4
GO:0030865	cortical cytoskeleton organization	7.834879e-4
GO:0043461	proton-transporting ATP synthase complex assembly	8.393674e-4
GO:0002407	dendritic cell chemotaxis	8.421421e-4
GO:0010216	maintenance of DNA methylation	8.465340e-4
GO:0060347	heart trabecula formation	8.521832e-4
GO:0042921	glucocorticoid receptor signaling pathway	8.521832e-4
GO:0033128	negative regulation of histone phosphorylation	8.876504e-4
GO:0043393	regulation of protein binding	9.099800e-4
GO:0045625	regulation of T-helper 1 cell differentiation	9.175687e-4
GO:0044257	cellular protein catabolic process	9.584739e-4
GO:0001570	vasculogenesis	9.736386e-4
GO:0070672	response to interleukin-15	1.073188e-3
GO:0045869	negative regulation of retroviral genome replication	1.073188e-3
GO:0001771	immunological synapse formation	1.078864e-3
GO:0043523	regulation of neuron apoptosis	1.110163e-3
GO:0034589	hydroxyproline transport	1.110402e-3
GO:0015826	threonine transport	1.110402e-3
GO:0019509	L-methionine salvage from methylthioadenosine	1.110402e-3
GO:0008635	activation of caspase activity by cytochrome c	1.129160e-3
GO:0060375	regulation of mast cell differentiation	1.132633e-3
GO:0007412	axon target recognition	1.148671e-3
GO:0019348	dolichol metabolic process	1.148671e-3
GO:0030163	protein catabolic process	1.163528e-3
GO:0090303	positive regulation of wound healing	1.172690e-3
GO:0003404	optic vesicle morphogenesis	1.182538e-3
GO:0021623	oculomotor nerve formation	1.182538e-3
GO:0071803	positive regulation of podosome assembly	1.182538e-3
GO:0003409	optic cup structural organization	1.182538e-3
GO:0051098	regulation of binding	1.188797e-3
GO:0070997	neuron death	1.228258e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.262823e-3
GO:0008625	induction of apoptosis via death domain receptors	1.265042e-3
GO:0061035	regulation of cartilage development	1.282617e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	1.322878e-3
GO:0060379	cardiac muscle cell myoblast differentiation	1.322878e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	1.322878e-3
GO:0031129	inductive cell-cell signaling	1.322878e-3
GO:0045123	cellular extravasation	1.336058e-3
GO:0061046	regulation of branching involved in lung morphogenesis	1.349500e-3
GO:0001707	mesoderm formation	1.390506e-3
GO:0072076	nephrogenic mesenchyme development	1.398422e-3
GO:0061364	apoptosis involved in luteolysis	1.398422e-3
GO:0045919	positive regulation of cytolysis	1.436789e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	1.480444e-3
GO:0043457	regulation of cellular respiration	1.502573e-3
GO:2000736	regulation of stem cell differentiation	1.510358e-3
GO:0031958	corticosteroid receptor signaling pathway	1.544476e-3
GO:0070842	aggresome assembly	1.565720e-3
GO:0048935	peripheral nervous system neuron development	1.573484e-3
GO:0030202	heparin metabolic process	1.583961e-3
GO:0045738	negative regulation of DNA repair	1.583961e-3
GO:0072092	ureteric bud invasion	1.583961e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.583961e-3
GO:0035988	chondrocyte proliferation	1.634130e-3
GO:2000685	positive regulation of cellular response to X-ray	1.634130e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	1.634130e-3
GO:2001038	regulation of cellular response to drug	1.634130e-3
GO:0035978	histone H2A-S139 phosphorylation	1.634130e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.634130e-3
GO:0006117	acetaldehyde metabolic process	1.634130e-3
GO:0003131	mesodermal-endodermal cell signaling	1.634130e-3
GO:0031052	chromosome breakage	1.634130e-3
GO:0060557	positive regulation of vitamin D biosynthetic process	1.635558e-3
GO:0045218	zonula adherens maintenance	1.635558e-3
GO:0033578	protein glycosylation in Golgi	1.635558e-3
GO:0006297	nucleotide-excision repair, DNA gap filling	1.635558e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	1.683793e-3
GO:0032288	myelin assembly	1.785986e-3
GO:0071711	basement membrane organization	1.813674e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.816364e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.820615e-3
GO:0043973	histone H3-K4 acetylation	1.820615e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.820615e-3
GO:0003017	lymph circulation	1.820615e-3
GO:0060686	negative regulation of prostatic bud formation	1.846539e-3
GO:0014741	negative regulation of muscle hypertrophy	1.846539e-3
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	1.883624e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	1.967873e-3
GO:0021559	trigeminal nerve development	1.981792e-3
GO:0015937	coenzyme A biosynthetic process	1.986845e-3
GO:0003338	metanephros morphogenesis	2.033792e-3
GO:0006342	chromatin silencing	2.057764e-3
GO:0060319	primitive erythrocyte differentiation	2.096891e-3
GO:0060992	response to fungicide	2.097810e-3
GO:0043949	regulation of cAMP-mediated signaling	2.105179e-3
GO:0016075	rRNA catabolic process	2.107711e-3
GO:0042245	RNA repair	2.121147e-3
GO:0021758	putamen development	2.121147e-3
GO:0021757	caudate nucleus development	2.121147e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	2.202592e-3
GO:0000042	protein targeting to Golgi	2.202592e-3
GO:0006396	RNA processing	2.203885e-3
GO:0019673	GDP-mannose metabolic process	2.218353e-3
GO:0060255	regulation of macromolecule metabolic process	2.230847e-3
GO:0031999	negative regulation of fatty acid beta-oxidation	2.258966e-3
GO:0043353	enucleate erythrocyte differentiation	2.259307e-3
GO:0006268	DNA unwinding involved in replication	2.259307e-3
GO:0006165	nucleoside diphosphate phosphorylation	2.259307e-3
GO:0006228	UTP biosynthetic process	2.259307e-3
GO:0034227	tRNA thio-modification	2.278563e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	2.289015e-3
GO:0046670	positive regulation of retinal cell programmed cell death	2.289015e-3
GO:0045226	extracellular polysaccharide biosynthetic process	2.301525e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	2.301525e-3
GO:0038027	apolipoprotein A-I-mediated signaling pathway	2.301525e-3
GO:0030514	negative regulation of BMP signaling pathway	2.326784e-3
GO:0006448	regulation of translational elongation	2.347586e-3
GO:0006241	CTP biosynthetic process	2.406114e-3
GO:0060996	dendritic spine development	2.429025e-3
GO:0090342	regulation of cell aging	2.501591e-3
GO:0060318	definitive erythrocyte differentiation	2.564138e-3
GO:0031324	negative regulation of cellular metabolic process	2.605726e-3
GO:0007288	sperm axoneme assembly	2.632610e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	2.653120e-3
GO:0035621	ER to Golgi ceramide transport	2.757008e-3
GO:0030902	hindbrain development	2.763518e-3
GO:0007127	meiosis I	2.838751e-3
GO:0045345	positive regulation of MHC class I biosynthetic process	2.845636e-3
GO:0071545	inositol phosphate catabolic process	2.897343e-3
GO:0010002	cardioblast differentiation	2.937744e-3
GO:0072355	histone H3-T3 phosphorylation	2.947210e-3
GO:0060821	inactivation of X chromosome by DNA methylation	2.947210e-3
GO:0019428	allantoin biosynthetic process	2.947210e-3
GO:0019858	cytosine metabolic process	2.947210e-3
GO:0008612	peptidyl-lysine modification to hypusine	2.962351e-3
GO:0002098	tRNA wobble uridine modification	2.962351e-3
GO:0006282	regulation of DNA repair	2.970412e-3
GO:0043922	negative regulation by host of viral transcription	3.017742e-3
GO:0035082	axoneme assembly	3.017742e-3
GO:0080090	regulation of primary metabolic process	3.032307e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3.111781e-3
GO:0045071	negative regulation of viral genome replication	3.151486e-3
GO:0007257	activation of JUN kinase activity	3.285431e-3
GO:0010159	specification of organ position	3.319370e-3
GO:0006183	GTP biosynthetic process	3.319370e-3
GO:0010557	positive regulation of macromolecule biosynthetic process	3.354627e-3
GO:0006308	DNA catabolic process	3.364197e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.409105e-3
GO:0061042	vascular wound healing	3.447365e-3
GO:0071298	cellular response to L-ascorbic acid	3.447365e-3
GO:0042335	cuticle development	3.447365e-3
GO:2000366	positive regulation of STAT protein import into nucleus	3.447365e-3
GO:0060587	regulation of lipoprotein lipid oxidation	3.447365e-3
GO:0015854	guanine transport	3.447365e-3
GO:0033686	positive regulation of luteinizing hormone secretion	3.447365e-3
GO:0035344	hypoxanthine transport	3.447365e-3
GO:0035364	thymine transport	3.447365e-3
GO:0015853	adenine transport	3.447365e-3
GO:0048525	negative regulation of viral reproduction	3.539287e-3
GO:2000195	negative regulation of female gonad development	3.582393e-3
GO:0030730	sequestering of triglyceride	3.582393e-3
GO:0032897	negative regulation of viral transcription	3.585912e-3
GO:0032252	secretory granule localization	3.713532e-3
GO:2000380	regulation of mesoderm development	3.729123e-3
GO:0061037	negative regulation of cartilage development	3.729123e-3
GO:0002921	negative regulation of humoral immune response	3.729123e-3
GO:0060419	heart growth	3.743332e-3
GO:0009451	RNA modification	3.749853e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	3.755498e-3
GO:0007140	male meiosis	3.869057e-3
GO:0010628	positive regulation of gene expression	3.869544e-3
GO:0016458	gene silencing	3.888432e-3
GO:0070172	positive regulation of tooth mineralization	3.896087e-3
GO:0007352	zygotic specification of dorsal/ventral axis	3.896087e-3
GO:0006471	protein ADP-ribosylation	3.936081e-3
GO:0032851	positive regulation of Rab GTPase activity	3.975936e-3
GO:0048846	axon extension involved in axon guidance	3.987685e-3
GO:0071316	cellular response to nicotine	4.123076e-3
GO:0035552	oxidative single-stranded DNA demethylation	4.172865e-3
GO:0031055	chromatin remodeling at centromere	4.172865e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.184237e-3
GO:0060977	coronary vasculature morphogenesis	4.204338e-3
GO:0043921	modulation by host of viral transcription	4.210774e-3
GO:0010665	regulation of cardiac muscle cell apoptosis	4.345141e-3
GO:0007064	mitotic sister chromatid cohesion	4.357070e-3
GO:0090074	negative regulation of protein homodimerization activity	4.434629e-3
GO:0048343	paraxial mesodermal cell fate commitment	4.434629e-3
GO:0032313	regulation of Rab GTPase activity	4.448263e-3
GO:0009892	negative regulation of metabolic process	4.479517e-3
GO:0001835	blastocyst hatching	4.583788e-3
GO:0035966	response to topologically incorrect protein	4.616679e-3
GO:2000272	negative regulation of receptor activity	4.726710e-3
GO:0043170	macromolecule metabolic process	4.752981e-3
GO:0060612	adipose tissue development	4.791224e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	4.811847e-3
GO:0060217	hemangioblast cell differentiation	4.811847e-3
GO:0050689	negative regulation of defense response to virus by host	4.811847e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	4.811847e-3
GO:0003241	growth involved in heart morphogenesis	4.811847e-3
GO:0006713	glucocorticoid catabolic process	4.811847e-3
GO:0032927	positive regulation of activin receptor signaling pathway	4.811847e-3
GO:0031503	protein complex localization	4.928277e-3
GO:0032364	oxygen homeostasis	4.991407e-3
GO:0000185	activation of MAPKKK activity	5.166031e-3
GO:0030510	regulation of BMP signaling pathway	5.210632e-3
GO:0021697	cerebellar cortex formation	5.210760e-3
GO:0051955	regulation of amino acid transport	5.278830e-3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.440409e-3
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	5.502679e-3
GO:0000422	mitochondrion degradation	5.502679e-3
GO:0045647	negative regulation of erythrocyte differentiation	5.625730e-3
GO:0002649	regulation of tolerance induction to self antigen	5.644518e-3
GO:0033108	mitochondrial respiratory chain complex assembly	5.717519e-3
GO:0000209	protein polyubiquitination	5.739310e-3
GO:0003108	negative regulation of the force of heart contraction by chemical signal	5.807169e-3
GO:0010312	detoxification of zinc ion	5.812795e-3
GO:0009755	hormone-mediated signaling pathway	5.820463e-3
GO:0015936	coenzyme A metabolic process	5.847623e-3
GO:0051798	positive regulation of hair follicle development	5.848687e-3
GO:0003100	regulation of systemic arterial blood pressure by endothelin	5.893246e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	6.042017e-3
GO:0021528	commissural neuron differentiation in spinal cord	6.042017e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	6.042017e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	6.042017e-3
GO:0003210	cardiac atrium formation	6.042017e-3
GO:0003236	sinus venosus morphogenesis	6.042017e-3
GO:0003259	cardioblast anterior-lateral migration	6.042017e-3
GO:0015811	L-cystine transport	6.183761e-3
GO:0006418	tRNA aminoacylation for protein translation	6.343506e-3
GO:0060754	positive regulation of mast cell chemotaxis	6.538169e-3
GO:0060911	cardiac cell fate commitment	6.636863e-3
GO:0033483	gas homeostasis	6.636863e-3
GO:0051103	DNA ligation involved in DNA repair	6.688313e-3
GO:0048640	negative regulation of developmental growth	6.732172e-3
GO:0072205	metanephric collecting duct development	6.780526e-3
GO:0003281	ventricular septum development	6.808905e-3
GO:0060556	regulation of vitamin D biosynthetic process	6.899480e-3
GO:0006338	chromatin remodeling	6.993249e-3
GO:0051533	positive regulation of NFAT protein import into nucleus	7.144841e-3
GO:2000194	regulation of female gonad development	7.256112e-3
GO:0045065	cytotoxic T cell differentiation	7.275587e-3
GO:0010614	negative regulation of cardiac muscle hypertrophy	7.275587e-3
GO:0035404	histone-serine phosphorylation	7.275587e-3
GO:0051321	meiotic cell cycle	7.424501e-3
GO:0006366	transcription from RNA polymerase II promoter	7.531372e-3
GO:0001963	synaptic transmission, dopaminergic	7.579955e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	7.795711e-3
GO:0042659	regulation of cell fate specification	7.797720e-3
GO:0032342	aldosterone biosynthetic process	7.802392e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	7.813143e-3
GO:0045814	negative regulation of gene expression, epigenetic	7.836554e-3
GO:0048671	negative regulation of collateral sprouting	7.884799e-3
GO:0072348	sulfur compound transport	7.884799e-3
GO:0032060	bleb assembly	7.884799e-3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	7.887874e-3
GO:0060004	reflex	8.145416e-3
GO:0010724	regulation of definitive erythrocyte differentiation	8.173024e-3
GO:0006705	mineralocorticoid biosynthetic process	8.173024e-3
GO:0000395	nuclear mRNA 5'-splice site recognition	8.348041e-3
GO:0060921	sinoatrial node cell differentiation	8.368075e-3
GO:0006863	purine base transport	8.368075e-3
GO:0006513	protein monoubiquitination	8.470767e-3
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	8.495904e-3
GO:0072198	mesenchymal cell proliferation involved in ureter development	8.607322e-3
GO:0072192	ureter epithelial cell differentiation	8.607322e-3
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	8.607322e-3
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	8.607322e-3
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	8.607322e-3
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	8.607322e-3
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	8.607322e-3
GO:0090194	negative regulation of glomerulus development	8.607322e-3
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	8.607322e-3
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	8.607322e-3
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	8.607322e-3
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	8.607322e-3
GO:0048392	intermediate mesodermal cell differentiation	8.607322e-3
GO:0007500	mesodermal cell fate determination	8.607322e-3
GO:0060503	bud dilation involved in lung branching	8.607322e-3
GO:0055020	positive regulation of cardiac muscle fiber development	8.607322e-3
GO:0071893	BMP signaling pathway involved in nephric duct formation	8.607322e-3
GO:0061155	pulmonary artery endothelial tube morphogenesis	8.607322e-3
GO:0061151	BMP signaling pathway involved in renal system segmentation	8.607322e-3
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	8.607322e-3
GO:0009108	coenzyme biosynthetic process	8.611906e-3
GO:0001869	negative regulation of complement activation, lectin pathway	8.683831e-3
GO:2000737	negative regulation of stem cell differentiation	8.683831e-3
GO:0032915	positive regulation of transforming growth factor beta2 production	8.683831e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	8.724257e-3
GO:0060033	anatomical structure regression	8.863781e-3
GO:2000779	regulation of double-strand break repair	8.959379e-3
GO:0007525	somatic muscle development	8.971248e-3
GO:0048246	macrophage chemotaxis	8.971248e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	8.988815e-3
GO:0042384	cilium assembly	8.994642e-3
GO:0043526	neuroprotection	9.156005e-3
GO:0046498	S-adenosylhomocysteine metabolic process	9.170176e-3
GO:0032508	DNA duplex unwinding	9.170176e-3
GO:0043484	regulation of RNA splicing	9.174593e-3
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	9.286458e-3
GO:0007369	gastrulation	9.543507e-3
GO:0001816	cytokine production	9.555936e-3
GO:0070989	oxidative demethylation	9.614207e-3
GO:0021603	cranial nerve formation	9.614207e-3
GO:0070584	mitochondrion morphogenesis	1.007425e-2
GO:0060038	cardiac muscle cell proliferation	1.012832e-2
GO:0071459	protein localization to chromosome, centromeric region	1.013768e-2
GO:0070194	synaptonemal complex disassembly	1.017755e-2
GO:0014063	negative regulation of serotonin secretion	1.017755e-2
GO:0010424	DNA methylation on cytosine within a CG sequence	1.021330e-2
GO:0035511	oxidative DNA demethylation	1.021330e-2
GO:0003156	regulation of organ formation	1.030168e-2
GO:0015851	nucleobase transport	1.039342e-2
GO:0007619	courtship behavior	1.039342e-2
GO:0034067	protein localization in Golgi apparatus	1.042034e-2