Novel motif:162

name:	motif162_AGTTACCGTCA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0046032	ADP catabolic process	7.070157e-13
GO:0046709	IDP catabolic process	7.070157e-13
GO:0045214	sarcomere organization	1.404690e-11
GO:0043623	cellular protein complex assembly	8.274964e-11
GO:0060415	muscle tissue morphogenesis	2.548972e-10
GO:0055008	cardiac muscle tissue morphogenesis	2.992114e-10
GO:0048769	sarcomerogenesis	3.853452e-10
GO:0015942	formate metabolic process	4.062762e-10
GO:0009181	purine ribonucleoside diphosphate catabolic process	1.034238e-9
GO:0002684	positive regulation of immune system process	1.270045e-9
GO:0006941	striated muscle contraction	3.227687e-9
GO:0048739	cardiac muscle fiber development	3.937335e-9
GO:0072594	establishment of protein localization to organelle	3.987017e-9
GO:0048644	muscle organ morphogenesis	5.224720e-9
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	7.754340e-9
GO:0009396	folic acid-containing compound biosynthetic process	8.397293e-9
GO:0009191	ribonucleoside diphosphate catabolic process	1.291323e-8
GO:0032467	positive regulation of cytokinesis	1.532394e-8
GO:0048205	COPI coating of Golgi vesicle	1.944970e-8
GO:0071777	positive regulation of cell cycle cytokinesis	2.288180e-8
GO:0003278	apoptosis involved in heart morphogenesis	2.573269e-8
GO:0010288	response to lead ion	2.922320e-8
GO:0022600	digestive system process	3.080184e-8
GO:0030241	skeletal muscle myosin thick filament assembly	4.525886e-8
GO:0048194	Golgi vesicle budding	5.205280e-8
GO:0043032	positive regulation of macrophage activation	5.654194e-8
GO:0006955	immune response	6.575948e-8
GO:0010038	response to metal ion	6.657861e-8
GO:0034622	cellular macromolecular complex assembly	1.072969e-7
GO:0007076	mitotic chromosome condensation	1.374698e-7
GO:0030239	myofibril assembly	1.920382e-7
GO:0030240	skeletal muscle thin filament assembly	1.931611e-7
GO:0033690	positive regulation of osteoblast proliferation	2.319838e-7
GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	2.334602e-7
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	2.334602e-7
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	2.334602e-7
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	2.334602e-7
GO:0051592	response to calcium ion	2.388413e-7
GO:0010927	cellular component assembly involved in morphogenesis	2.458361e-7
GO:2000505	regulation of energy homeostasis	2.862343e-7
GO:0022617	extracellular matrix disassembly	3.076501e-7
GO:0016558	protein import into peroxisome matrix	3.233605e-7
GO:0071800	podosome assembly	4.126065e-7
GO:0010759	positive regulation of macrophage chemotaxis	4.434998e-7
GO:0051649	establishment of localization in cell	4.599177e-7
GO:0031032	actomyosin structure organization	4.730288e-7
GO:0016064	immunoglobulin mediated immune response	4.961474e-7
GO:0071622	regulation of granulocyte chemotaxis	6.077843e-7
GO:0006457	protein folding	6.154242e-7
GO:0002576	platelet degranulation	6.418699e-7
GO:0010758	regulation of macrophage chemotaxis	7.194218e-7
GO:0009082	branched chain family amino acid biosynthetic process	7.280933e-7
GO:0006887	exocytosis	8.235726e-7
GO:0060164	regulation of timing of neuron differentiation	9.935507e-7
GO:0050892	intestinal absorption	1.035334e-6
GO:0002252	immune effector process	1.257163e-6
GO:0044267	cellular protein metabolic process	1.280095e-6
GO:0007586	digestion	1.319942e-6
GO:0043030	regulation of macrophage activation	1.353805e-6
GO:0006958	complement activation, classical pathway	1.353805e-6
GO:0032727	positive regulation of interferon-alpha production	1.601432e-6
GO:0071675	regulation of mononuclear cell migration	1.615039e-6
GO:0019724	B cell mediated immunity	1.900421e-6
GO:0006680	glucosylceramide catabolic process	1.924215e-6
GO:0070489	T cell aggregation	1.924215e-6
GO:0010623	developmental programmed cell death	1.935020e-6
GO:0002041	intussusceptive angiogenesis	1.967516e-6
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	2.204755e-6
GO:0055003	cardiac myofibril assembly	2.491755e-6
GO:2000304	positive regulation of ceramide biosynthetic process	2.768431e-6
GO:0002676	regulation of chronic inflammatory response	2.894872e-6
GO:0048747	muscle fiber development	3.340472e-6
GO:0010745	negative regulation of macrophage derived foam cell differentiation	3.615941e-6
GO:0048619	embryonic hindgut morphogenesis	3.849084e-6
GO:2000741	positive regulation of mesenchymal stem cell differentiation	4.027422e-6
GO:0006323	DNA packaging	4.084862e-6
GO:0007442	hindgut morphogenesis	4.568929e-6
GO:0032655	regulation of interleukin-12 production	4.881270e-6
GO:0023021	termination of signal transduction	5.030571e-6
GO:0002443	leukocyte mediated immunity	5.032504e-6
GO:2000303	regulation of ceramide biosynthetic process	5.859961e-6
GO:0019538	protein metabolic process	6.208263e-6
GO:0009083	branched chain family amino acid catabolic process	6.337626e-6
GO:0042559	pteridine-containing compound biosynthetic process	6.857917e-6
GO:0045321	leukocyte activation	7.380918e-6
GO:0061036	positive regulation of cartilage development	7.490146e-6
GO:0034621	cellular macromolecular complex subunit organization	7.993139e-6
GO:0007624	ultradian rhythm	8.565638e-6
GO:0046031	ADP metabolic process	9.344507e-6
GO:0010763	positive regulation of fibroblast migration	9.715898e-6
GO:2000507	positive regulation of energy homeostasis	1.047165e-5
GO:2000253	positive regulation of feeding behavior	1.047165e-5
GO:0032707	negative regulation of interleukin-23 production	1.154003e-5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.262966e-5
GO:0006605	protein targeting	1.296204e-5
GO:0051641	cellular localization	1.304224e-5
GO:0030299	intestinal cholesterol absorption	1.470888e-5
GO:0014866	skeletal myofibril assembly	1.555243e-5
GO:0003007	heart morphogenesis	1.570056e-5
GO:0000070	mitotic sister chromatid segregation	1.689514e-5
GO:0002577	regulation of antigen processing and presentation	1.717361e-5
GO:0032891	negative regulation of organic acid transport	1.753250e-5
GO:0002449	lymphocyte mediated immunity	1.904067e-5
GO:0044282	small molecule catabolic process	1.912375e-5
GO:0045075	regulation of interleukin-12 biosynthetic process	1.930051e-5
GO:0003181	atrioventricular valve morphogenesis	2.011533e-5
GO:0055002	striated muscle cell development	2.178354e-5
GO:0046967	cytosol to ER transport	2.295309e-5
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.324771e-5
GO:0002475	antigen processing and presentation via MHC class Ib	2.516814e-5
GO:0060658	nipple morphogenesis	2.920403e-5
GO:0006956	complement activation	3.053030e-5
GO:0002696	positive regulation of leukocyte activation	3.150242e-5
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	3.503319e-5
GO:0006542	glutamine biosynthetic process	3.719281e-5
GO:0000819	sister chromatid segregation	3.730848e-5
GO:0001775	cell activation	3.731843e-5
GO:0019320	hexose catabolic process	3.751331e-5
GO:0090161	Golgi ribbon formation	3.876864e-5
GO:0002682	regulation of immune system process	3.909933e-5
GO:0046365	monosaccharide catabolic process	4.055343e-5
GO:0010754	negative regulation of cGMP-mediated signaling	4.233131e-5
GO:0043652	engulfment of apoptotic cell	4.233131e-5
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	4.233131e-5
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	4.233131e-5
GO:0010751	negative regulation of nitric oxide mediated signal transduction	4.233131e-5
GO:0046512	sphingosine biosynthetic process	4.322713e-5
GO:0060649	mammary gland bud elongation	4.383409e-5
GO:0060659	nipple sheath formation	4.383409e-5
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	4.551642e-5
GO:0045760	positive regulation of action potential	4.672595e-5
GO:2000739	regulation of mesenchymal stem cell differentiation	4.710283e-5
GO:0016446	somatic hypermutation of immunoglobulin genes	4.951801e-5
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	5.069579e-5
GO:0019438	aromatic compound biosynthetic process	5.182701e-5
GO:0030431	sleep	5.359329e-5
GO:0046514	ceramide catabolic process	5.677472e-5
GO:0032369	negative regulation of lipid transport	5.996433e-5
GO:0032914	positive regulation of transforming growth factor beta1 production	6.141596e-5
GO:0006952	defense response	6.207531e-5
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	6.467241e-5
GO:0009179	purine ribonucleoside diphosphate metabolic process	7.130243e-5
GO:0051712	positive regulation of killing of cells of other organism	7.519632e-5
GO:0072376	protein activation cascade	8.094936e-5
GO:0070271	protein complex biogenesis	8.460722e-5
GO:0019371	cyclooxygenase pathway	8.582684e-5
GO:0050746	regulation of lipoprotein metabolic process	9.349473e-5
GO:0055078	sodium ion homeostasis	9.411482e-5
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	9.543201e-5
GO:0035545	determination of left/right asymmetry in nervous system	9.762301e-5
GO:0030538	embryonic genitalia morphogenesis	9.776708e-5
GO:0043412	macromolecule modification	9.939307e-5
GO:0009593	detection of chemical stimulus	1.008816e-4
GO:0032425	positive regulation of mismatch repair	1.009963e-4
GO:0051877	pigment granule aggregation in cell center	1.028794e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.054751e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.054751e-4
GO:0016046	detection of fungus	1.054751e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	1.072345e-4
GO:0050867	positive regulation of cell activation	1.078978e-4
GO:0006461	protein complex assembly	1.084483e-4
GO:0071403	cellular response to high density lipoprotein particle stimulus	1.097605e-4
GO:0071448	cellular response to alkyl hydroperoxide	1.097605e-4
GO:0031269	pseudopodium assembly	1.097605e-4
GO:0071315	cellular response to morphine	1.097605e-4
GO:0071307	cellular response to vitamin K	1.097605e-4
GO:0050904	diapedesis	1.097605e-4
GO:0009185	ribonucleoside diphosphate metabolic process	1.098702e-4
GO:0000413	protein peptidyl-prolyl isomerization	1.119034e-4
GO:0006464	protein modification process	1.134580e-4
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.154457e-4
GO:0048260	positive regulation of receptor-mediated endocytosis	1.183923e-4
GO:0006883	cellular sodium ion homeostasis	1.189593e-4
GO:0009081	branched chain family amino acid metabolic process	1.207814e-4
GO:0051258	protein polymerization	1.218851e-4
GO:0006954	inflammatory response	1.239693e-4
GO:0032465	regulation of cytokinesis	1.259968e-4
GO:0071103	DNA conformation change	1.274955e-4
GO:0010951	negative regulation of endopeptidase activity	1.301907e-4
GO:0006821	chloride transport	1.306685e-4
GO:0002678	positive regulation of chronic inflammatory response	1.307780e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1.318366e-4
GO:0045807	positive regulation of endocytosis	1.355723e-4
GO:0048245	eosinophil chemotaxis	1.359785e-4
GO:0060027	convergent extension involved in gastrulation	1.376319e-4
GO:0034613	cellular protein localization	1.411123e-4
GO:0007522	visceral muscle development	1.420798e-4
GO:0030048	actin filament-based movement	1.442886e-4
GO:0050776	regulation of immune response	1.470471e-4
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	1.525370e-4
GO:0046907	intracellular transport	1.572416e-4
GO:0006886	intracellular protein transport	1.576772e-4
GO:0065003	macromolecular complex assembly	1.578043e-4
GO:0050747	positive regulation of lipoprotein metabolic process	1.579204e-4
GO:0046968	peptide antigen transport	1.579204e-4
GO:0002281	macrophage activation involved in immune response	1.644616e-4
GO:0051606	detection of stimulus	1.727493e-4
GO:0051131	chaperone-mediated protein complex assembly	1.775096e-4
GO:0035234	germ cell programmed cell death	1.812229e-4
GO:0070727	cellular macromolecule localization	1.882339e-4
GO:0008634	negative regulation of survival gene product expression	1.904810e-4
GO:0046683	response to organophosphorus	1.929987e-4
GO:0033688	regulation of osteoblast proliferation	1.935658e-4
GO:0002251	organ or tissue specific immune response	1.944654e-4
GO:0002551	mast cell chemotaxis	2.003690e-4
GO:0046521	sphingoid catabolic process	2.042707e-4
GO:0045047	protein targeting to ER	2.070897e-4
GO:0006626	protein targeting to mitochondrion	2.076962e-4
GO:0042108	positive regulation of cytokine biosynthetic process	2.106110e-4
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	2.152090e-4
GO:0030261	chromosome condensation	2.155413e-4
GO:0046653	tetrahydrofolate metabolic process	2.204255e-4
GO:0002426	immunoglobulin production in mucosal tissue	2.209987e-4
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	2.278918e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	2.335318e-4
GO:0048199	vesicle targeting, to, from or within Golgi	2.453650e-4
GO:0002376	immune system process	2.459047e-4
GO:0002706	regulation of lymphocyte mediated immunity	2.464682e-4
GO:0072358	cardiovascular system development	2.647060e-4
GO:0033632	regulation of cell-cell adhesion mediated by integrin	2.712389e-4
GO:0015805	S-adenosylmethionine transport	2.753261e-4
GO:0055001	muscle cell development	2.777660e-4
GO:0002819	regulation of adaptive immune response	2.794644e-4
GO:0048280	vesicle fusion with Golgi apparatus	2.804275e-4
GO:0071477	cellular hypotonic salinity response	2.871338e-4
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	2.871338e-4
GO:0035635	entry of bacterium into host cell	2.871338e-4
GO:0051919	positive regulation of fibrinolysis	2.871338e-4
GO:0030049	muscle filament sliding	2.935119e-4
GO:0010666	positive regulation of cardiac muscle cell apoptosis	2.952244e-4
GO:0051650	establishment of vesicle localization	2.995556e-4
GO:0032695	negative regulation of interleukin-12 production	3.027463e-4
GO:0061035	regulation of cartilage development	3.069799e-4
GO:0003209	cardiac atrium morphogenesis	3.091669e-4
GO:0048259	regulation of receptor-mediated endocytosis	3.146540e-4
GO:0006625	protein targeting to peroxisome	3.173473e-4
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	3.433054e-4
GO:0060716	labyrinthine layer blood vessel development	3.486706e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.521478e-4
GO:0031508	centromeric heterochromatin formation	3.578092e-4
GO:0046500	S-adenosylmethionine metabolic process	3.578103e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	3.595538e-4
GO:0051246	regulation of protein metabolic process	3.638247e-4
GO:0044258	intestinal lipid catabolic process	3.680073e-4
GO:0018350	protein esterification	3.680073e-4
GO:0006259	DNA metabolic process	3.688222e-4
GO:0017085	response to insecticide	3.742232e-4
GO:0030277	maintenance of gastrointestinal epithelium	3.828743e-4
GO:0002385	mucosal immune response	3.848177e-4
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	3.916238e-4
GO:0035459	cargo loading into vesicle	3.978028e-4
GO:0072393	microtubule anchoring at microtubule organizing center	3.989344e-4
GO:0060648	mammary gland bud morphogenesis	3.989344e-4
GO:0034112	positive regulation of homotypic cell-cell adhesion	3.993615e-4
GO:0010888	negative regulation of lipid storage	4.054296e-4
GO:0006007	glucose catabolic process	4.176697e-4
GO:0071593	lymphocyte aggregation	4.241921e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	4.413876e-4
GO:0055013	cardiac muscle cell development	4.420916e-4
GO:0009236	cobalamin biosynthetic process	4.581684e-4
GO:0070252	actin-mediated cell contraction	4.613592e-4
GO:0031268	pseudopodium organization	4.737721e-4
GO:0050778	positive regulation of immune response	4.776286e-4
GO:0006911	phagocytosis, engulfment	4.793005e-4
GO:0051917	regulation of fibrinolysis	4.806538e-4
GO:0090307	spindle assembly involved in mitosis	5.010762e-4
GO:0043574	peroxisomal transport	5.029681e-4
GO:0072593	reactive oxygen species metabolic process	5.330613e-4
GO:0071569	protein ufmylation	5.514531e-4
GO:0006760	folic acid-containing compound metabolic process	5.645039e-4
GO:0000082	G1/S transition of mitotic cell cycle	5.650817e-4
GO:0045727	positive regulation of translation	5.723597e-4
GO:0032940	secretion by cell	5.726132e-4
GO:0007173	epidermal growth factor receptor signaling pathway	5.857362e-4
GO:0006546	glycine catabolic process	5.967099e-4
GO:0046164	alcohol catabolic process	6.425074e-4
GO:0021544	subpallium development	6.436798e-4
GO:0032332	positive regulation of chondrocyte differentiation	6.462530e-4
GO:0002699	positive regulation of immune effector process	6.489547e-4
GO:0048505	regulation of timing of cell differentiation	6.514843e-4
GO:0072678	T cell migration	6.599043e-4
GO:0006953	acute-phase response	6.744164e-4
GO:0043405	regulation of MAP kinase activity	6.927605e-4
GO:0060674	placenta blood vessel development	6.947703e-4
GO:0002366	leukocyte activation involved in immune response	7.017620e-4
GO:0002694	regulation of leukocyte activation	7.162726e-4
GO:0060632	regulation of microtubule-based movement	7.285161e-4
GO:0000165	MAPKKK cascade	7.520815e-4
GO:0003230	cardiac atrium development	7.608170e-4
GO:0043537	negative regulation of blood vessel endothelial cell migration	7.762140e-4
GO:0002697	regulation of immune effector process	7.764692e-4
GO:0051412	response to corticosterone stimulus	7.829878e-4
GO:0015780	nucleotide-sugar transport	8.233932e-4
GO:0042035	regulation of cytokine biosynthetic process	8.321300e-4
GO:0006839	mitochondrial transport	8.423944e-4
GO:0001525	angiogenesis	8.648026e-4
GO:0042984	regulation of amyloid precursor protein biosynthetic process	8.705829e-4
GO:0006909	phagocytosis	8.741384e-4
GO:0002687	positive regulation of leukocyte migration	8.947771e-4
GO:0042119	neutrophil activation	8.987899e-4
GO:0046649	lymphocyte activation	9.219624e-4
GO:0002537	nitric oxide production involved in inflammatory response	9.372122e-4
GO:0006412	translation	9.627735e-4
GO:0055119	relaxation of cardiac muscle	9.632999e-4
GO:0051895	negative regulation of focal adhesion assembly	9.752051e-4
GO:0007031	peroxisome organization	9.782788e-4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	9.800291e-4
GO:0080134	regulation of response to stress	9.821226e-4
GO:0002377	immunoglobulin production	9.851242e-4
GO:0051709	regulation of killing of cells of other organism	9.887986e-4
GO:0046395	carboxylic acid catabolic process	9.903750e-4
GO:0071353	cellular response to interleukin-4	1.004461e-3
GO:0046902	regulation of mitochondrial membrane permeability	1.004879e-3
GO:0017038	protein import	1.018926e-3
GO:0035518	histone H2A monoubiquitination	1.029577e-3
GO:0032908	regulation of transforming growth factor beta1 production	1.043545e-3
GO:0010466	negative regulation of peptidase activity	1.049087e-3
GO:0010661	positive regulation of muscle cell apoptosis	1.049248e-3
GO:0002200	somatic diversification of immune receptors	1.054524e-3
GO:0034446	substrate adhesion-dependent cell spreading	1.066142e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.093684e-3
GO:0032026	response to magnesium ion	1.111947e-3
GO:0032330	regulation of chondrocyte differentiation	1.141134e-3
GO:0070383	DNA cytosine deamination	1.145372e-3
GO:0070668	positive regulation of mast cell proliferation	1.167072e-3
GO:0043558	regulation of translational initiation in response to stress	1.170627e-3
GO:0034501	protein localization to kinetochore	1.170627e-3
GO:0006096	glycolysis	1.192653e-3
GO:0051648	vesicle localization	1.193851e-3
GO:0032423	regulation of mismatch repair	1.209975e-3
GO:0044241	lipid digestion	1.239248e-3
GO:0002250	adaptive immune response	1.240859e-3
GO:0060920	pacemaker cell differentiation	1.247495e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.253548e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.265539e-3
GO:2000425	regulation of apoptotic cell clearance	1.308845e-3
GO:0044068	modulation by symbiont of host cellular process	1.319937e-3
GO:0002253	activation of immune response	1.333185e-3
GO:0018208	peptidyl-proline modification	1.351373e-3
GO:0031341	regulation of cell killing	1.370069e-3
GO:0072655	establishment of protein localization in mitochondrion	1.386764e-3
GO:0006434	seryl-tRNA aminoacylation	1.391457e-3
GO:0045069	regulation of viral genome replication	1.394408e-3
GO:0071822	protein complex subunit organization	1.410438e-3
GO:0007005	mitochondrion organization	1.438558e-3
GO:0002709	regulation of T cell mediated immunity	1.441474e-3
GO:0002690	positive regulation of leukocyte chemotaxis	1.446256e-3
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	1.465429e-3
GO:0043933	macromolecular complex subunit organization	1.468707e-3
GO:0008298	intracellular mRNA localization	1.483366e-3
GO:0032647	regulation of interferon-alpha production	1.502078e-3
GO:0090197	positive regulation of chemokine secretion	1.506378e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1.506378e-3
GO:0060259	regulation of feeding behavior	1.507437e-3
GO:0048845	venous blood vessel morphogenesis	1.511857e-3
GO:0042450	arginine biosynthetic process via ornithine	1.517538e-3
GO:0006901	vesicle coating	1.530083e-3
GO:0002703	regulation of leukocyte mediated immunity	1.564291e-3
GO:0048285	organelle fission	1.568218e-3
GO:0051385	response to mineralocorticoid stimulus	1.577632e-3
GO:0042176	regulation of protein catabolic process	1.582680e-3
GO:0032890	regulation of organic acid transport	1.586043e-3
GO:0001816	cytokine production	1.588781e-3
GO:0008272	sulfate transport	1.608182e-3
GO:0044275	cellular carbohydrate catabolic process	1.615547e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.623737e-3
GO:0031295	T cell costimulation	1.628159e-3
GO:0072385	minus-end-directed organelle transport along microtubule	1.651772e-3
GO:0045061	thymic T cell selection	1.659356e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.662620e-3
GO:0031349	positive regulation of defense response	1.704695e-3
GO:0007018	microtubule-based movement	1.708231e-3
GO:0006891	intra-Golgi vesicle-mediated transport	1.715192e-3
GO:0055118	negative regulation of cardiac muscle contraction	1.735523e-3
GO:0006527	arginine catabolic process	1.735523e-3
GO:0002344	B cell affinity maturation	1.743285e-3
GO:0045039	protein import into mitochondrial inner membrane	1.778821e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	1.778987e-3
GO:0019220	regulation of phosphate metabolic process	1.786384e-3
GO:0006099	tricarboxylic acid cycle	1.790380e-3
GO:0046483	heterocycle metabolic process	1.790430e-3
GO:0071636	positive regulation of transforming growth factor beta production	1.823766e-3
GO:0034655	nucleobase-containing compound catabolic process	1.839389e-3
GO:0033365	protein localization to organelle	1.844894e-3
GO:0051384	response to glucocorticoid stimulus	1.849600e-3
GO:0010955	negative regulation of protein processing	1.853233e-3
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.905511e-3
GO:0030252	growth hormone secretion	1.922542e-3
GO:0046356	acetyl-CoA catabolic process	1.933266e-3
GO:0042663	regulation of endodermal cell fate specification	1.950159e-3
GO:0031343	positive regulation of cell killing	1.960300e-3
GO:0006084	acetyl-CoA metabolic process	1.973787e-3
GO:0060572	morphogenesis of an epithelial bud	2.016797e-3
GO:0070585	protein localization in mitochondrion	2.036158e-3
GO:0071361	cellular response to ethanol	2.046023e-3
GO:0032872	regulation of stress-activated MAPK cascade	2.092945e-3
GO:0002889	regulation of immunoglobulin mediated immune response	2.098360e-3
GO:0051918	negative regulation of fibrinolysis	2.111328e-3
GO:0045087	innate immune response	2.113605e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.152374e-3
GO:0030705	cytoskeleton-dependent intracellular transport	2.184742e-3
GO:0006687	glycosphingolipid metabolic process	2.188267e-3
GO:0006672	ceramide metabolic process	2.207232e-3
GO:0035606	peptidyl-cysteine S-trans-nitrosylation	2.227027e-3
GO:0043064	flagellum organization	2.299410e-3
GO:0002440	production of molecular mediator of immune response	2.324526e-3
GO:0060972	left/right pattern formation	2.331797e-3
GO:0060729	intestinal epithelial structure maintenance	2.331797e-3
GO:0051256	spindle midzone assembly involved in mitosis	2.369838e-3
GO:0002712	regulation of B cell mediated immunity	2.425806e-3
GO:0006730	one-carbon metabolic process	2.451695e-3
GO:0045006	DNA deamination	2.462946e-3
GO:0006458	'de novo' protein folding	2.484476e-3
GO:0016032	viral reproduction	2.495774e-3
GO:0010536	positive regulation of activation of Janus kinase activity	2.499069e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	2.499069e-3
GO:0018149	peptide cross-linking	2.522075e-3
GO:0003281	ventricular septum development	2.564246e-3
GO:0002274	myeloid leukocyte activation	2.614595e-3
GO:0050870	positive regulation of T cell activation	2.619105e-3
GO:0071560	cellular response to transforming growth factor beta stimulus	2.621429e-3
GO:0051084	'de novo' posttranslational protein folding	2.636005e-3
GO:0051881	regulation of mitochondrial membrane potential	2.677385e-3
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	2.714445e-3
GO:0045204	MAPK export from nucleus	2.714445e-3
GO:0048520	positive regulation of behavior	2.730307e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2.731607e-3
GO:0060009	Sertoli cell development	2.734537e-3
GO:0031347	regulation of defense response	2.766274e-3
GO:0010950	positive regulation of endopeptidase activity	2.770628e-3
GO:0048630	skeletal muscle tissue growth	2.773519e-3
GO:0007217	tachykinin receptor signaling pathway	2.773519e-3
GO:0002825	regulation of T-helper 1 type immune response	2.808338e-3
GO:0034605	cellular response to heat	2.835373e-3
GO:0015788	UDP-N-acetylglucosamine transport	2.867517e-3
GO:0035304	regulation of protein dephosphorylation	2.884900e-3
GO:0010035	response to inorganic substance	2.895412e-3
GO:0007507	heart development	2.909866e-3
GO:0090075	relaxation of muscle	2.924041e-3
GO:0010766	negative regulation of sodium ion transport	2.924041e-3
GO:0002831	regulation of response to biotic stimulus	2.954111e-3
GO:0032715	negative regulation of interleukin-6 production	2.973802e-3
GO:0072529	pyrimidine-containing compound catabolic process	3.035708e-3
GO:0010608	posttranscriptional regulation of gene expression	3.059990e-3
GO:0042116	macrophage activation	3.066808e-3
GO:0032103	positive regulation of response to external stimulus	3.107171e-3
GO:0046835	carbohydrate phosphorylation	3.113978e-3
GO:0015809	arginine transport	3.113978e-3
GO:0003222	ventricular trabecular myocardium morphogenesis	3.132384e-3
GO:0007006	mitochondrial membrane organization	3.142019e-3
GO:0032402	melanosome transport	3.219107e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	3.277227e-3
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	3.277227e-3
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	3.277227e-3
GO:0048806	genitalia development	3.361434e-3
GO:0010529	negative regulation of transposition	3.364154e-3
GO:0043549	regulation of kinase activity	3.380737e-3
GO:0043666	regulation of phosphoprotein phosphatase activity	3.389033e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	3.419984e-3
GO:0071476	cellular hypotonic response	3.517702e-3
GO:0001942	hair follicle development	3.523566e-3
GO:0060928	atrioventricular node cell development	3.581158e-3
GO:0060929	atrioventricular node cell fate commitment	3.581158e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	3.581158e-3
GO:0034120	positive regulation of erythrocyte aggregation	3.581158e-3
GO:0006437	tyrosyl-tRNA aminoacylation	3.581158e-3
GO:0003342	proepicardium development	3.581158e-3
GO:0010757	negative regulation of plasminogen activation	3.590264e-3
GO:0042558	pteridine-containing compound metabolic process	3.595213e-3
GO:0009063	cellular amino acid catabolic process	3.635363e-3
GO:0008652	cellular amino acid biosynthetic process	3.650630e-3
GO:0032790	ribosome disassembly	3.672583e-3
GO:0034763	negative regulation of transmembrane transport	3.694146e-3
GO:0006020	inositol metabolic process	3.717496e-3
GO:0042633	hair cycle	3.891183e-3
GO:0006003	fructose 2,6-bisphosphate metabolic process	3.926540e-3
GO:0042325	regulation of phosphorylation	3.930995e-3
GO:0000266	mitochondrial fission	3.932334e-3
GO:0014823	response to activity	3.954765e-3
GO:0042297	vocal learning	3.979173e-3
GO:0071472	cellular response to salt stress	3.979173e-3
GO:0030070	insulin processing	3.979173e-3
GO:0006903	vesicle targeting	4.003451e-3
GO:0009164	nucleoside catabolic process	4.027522e-3
GO:0045650	negative regulation of macrophage differentiation	4.078462e-3
GO:0090224	regulation of spindle organization	4.155574e-3
GO:0006413	translational initiation	4.163984e-3
GO:0033153	T cell receptor V(D)J recombination	4.165160e-3
GO:0030187	melatonin biosynthetic process	4.276384e-3
GO:0001914	regulation of T cell mediated cytotoxicity	4.283985e-3
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	4.286268e-3
GO:0048514	blood vessel morphogenesis	4.339538e-3
GO:0002339	B cell selection	4.406323e-3
GO:0002821	positive regulation of adaptive immune response	4.455346e-3
GO:0032224	positive regulation of synaptic transmission, cholinergic	4.483921e-3
GO:0043271	negative regulation of ion transport	4.518654e-3
GO:0072091	regulation of stem cell proliferation	4.524300e-3
GO:0016048	detection of temperature stimulus	4.570057e-3
GO:0002826	negative regulation of T-helper 1 type immune response	4.570057e-3
GO:0045070	positive regulation of viral genome replication	4.637683e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	4.859150e-9
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	7.766737e-7
GO:0033382	maintenance of granzyme B location in T cell secretory granule	8.689332e-7
GO:0033373	maintenance of protease location in mast cell secretory granule	8.689332e-7
GO:0060154	cellular process regulating host cell cycle in response to virus	1.829995e-6
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	2.045537e-6
GO:0055013	cardiac muscle cell development	3.523379e-6
GO:0010955	negative regulation of protein processing	3.594206e-6
GO:0018149	peptide cross-linking	3.699412e-6
GO:0003350	pulmonary myocardium development	4.656760e-6
GO:0046373	L-arabinose metabolic process	4.979264e-6
GO:0043366	beta selection	6.361060e-6
GO:0019054	modulation by virus of host cellular process	6.538998e-6
GO:0032609	interferon-gamma production	6.582643e-6
GO:0006507	GPI anchor release	8.421886e-6
GO:0034097	response to cytokine stimulus	8.454378e-6
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	9.726181e-6
GO:0048668	collateral sprouting	1.019395e-5
GO:0090307	spindle assembly involved in mitosis	1.019395e-5
GO:0055006	cardiac cell development	1.157403e-5
GO:0031396	regulation of protein ubiquitination	1.241526e-5
GO:0031397	negative regulation of protein ubiquitination	1.276247e-5
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	1.677114e-5
GO:0043056	forward locomotion	2.316209e-5
GO:0060658	nipple morphogenesis	2.772759e-5
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	3.025955e-5
GO:0051788	response to misfolded protein	3.132951e-5
GO:0071356	cellular response to tumor necrosis factor	3.147730e-5
GO:0008625	induction of apoptosis via death domain receptors	3.510478e-5
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	3.551852e-5
GO:0033364	mast cell secretory granule organization	3.620060e-5
GO:0061088	regulation of sequestering of zinc ion	3.720061e-5
GO:0045916	negative regulation of complement activation	3.733906e-5
GO:0006116	NADH oxidation	3.733906e-5
GO:0007099	centriole replication	4.286607e-5
GO:0034612	response to tumor necrosis factor	4.993235e-5
GO:0043543	protein acylation	5.736255e-5
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	6.148426e-5
GO:0070613	regulation of protein processing	6.740652e-5
GO:0051310	metaphase plate congression	7.238794e-5
GO:0030204	chondroitin sulfate metabolic process	7.526950e-5
GO:0033363	secretory granule organization	8.112865e-5
GO:0031018	endocrine pancreas development	8.684494e-5
GO:0050869	negative regulation of B cell activation	9.078363e-5
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	1.012310e-4
GO:0033143	regulation of steroid hormone receptor signaling pathway	1.097731e-4
GO:0060537	muscle tissue development	1.138627e-4
GO:0006955	immune response	1.190209e-4
GO:0001869	negative regulation of complement activation, lectin pathway	1.199863e-4
GO:0007229	integrin-mediated signaling pathway	1.205873e-4
GO:0033058	directional locomotion	1.315716e-4
GO:0002921	negative regulation of humoral immune response	1.379364e-4
GO:0043137	DNA replication, removal of RNA primer	1.393850e-4
GO:0018364	peptidyl-glutamine methylation	1.393850e-4
GO:0046632	alpha-beta T cell differentiation	1.487993e-4
GO:2000078	positive regulation of type B pancreatic cell development	1.594900e-4
GO:0035928	rRNA import into mitochondrion	1.594900e-4
GO:0034139	regulation of toll-like receptor 3 signaling pathway	1.649458e-4
GO:0051303	establishment of chromosome localization	1.701284e-4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.870269e-4
GO:0060841	venous blood vessel development	1.911426e-4
GO:0071345	cellular response to cytokine stimulus	1.916395e-4
GO:0046640	regulation of alpha-beta T cell proliferation	1.937875e-4
GO:0014706	striated muscle tissue development	1.939703e-4
GO:0030856	regulation of epithelial cell differentiation	1.978898e-4
GO:0010625	positive regulation of Schwann cell proliferation	2.022941e-4
GO:0043967	histone H4 acetylation	2.024094e-4
GO:0060427	lung connective tissue development	2.086044e-4
GO:0006278	RNA-dependent DNA replication	2.188977e-4
GO:0048213	Golgi vesicle prefusion complex stabilization	2.359051e-4
GO:0033209	tumor necrosis factor-mediated signaling pathway	2.544763e-4
GO:0050710	negative regulation of cytokine secretion	2.612194e-4
GO:0055003	cardiac myofibril assembly	2.693192e-4
GO:0008624	induction of apoptosis by extracellular signals	2.744623e-4
GO:0007080	mitotic metaphase plate congression	2.793210e-4
GO:0006273	lagging strand elongation	2.847092e-4
GO:0045579	positive regulation of B cell differentiation	2.929402e-4
GO:0046631	alpha-beta T cell activation	3.011267e-4
GO:0022007	convergent extension involved in neural plate elongation	3.052094e-4
GO:0006473	protein acetylation	3.251542e-4
GO:0045079	negative regulation of chemokine biosynthetic process	3.420639e-4
GO:0050821	protein stabilization	3.891984e-4
GO:0007144	female meiosis I	3.902791e-4
GO:0030449	regulation of complement activation	3.987431e-4
GO:0072259	metanephric interstitial cell development	4.143150e-4
GO:0072208	metanephric smooth muscle tissue development	4.143150e-4
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	4.143150e-4
GO:0072184	renal vesicle progenitor cell differentiation	4.143150e-4
GO:0072168	specification of anterior mesonephric tubule identity	4.143150e-4
GO:0072169	specification of posterior mesonephric tubule identity	4.143150e-4
GO:0002366	leukocyte activation involved in immune response	4.428746e-4
GO:0060174	limb bud formation	4.483807e-4
GO:0002281	macrophage activation involved in immune response	4.529460e-4
GO:0030388	fructose 1,6-bisphosphate metabolic process	4.726416e-4
GO:0007130	synaptonemal complex assembly	4.752205e-4
GO:0007340	acrosome reaction	5.179145e-4
GO:0071477	cellular hypotonic salinity response	5.229084e-4
GO:0072141	renal interstitial cell development	5.269014e-4
GO:0019221	cytokine-mediated signaling pathway	5.416633e-4
GO:0018193	peptidyl-amino acid modification	5.617164e-4
GO:0072608	interleukin-10 secretion	5.724153e-4
GO:0072643	interferon-gamma secretion	5.724153e-4
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	5.724153e-4
GO:0090198	negative regulation of chemokine secretion	5.724153e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	5.724153e-4
GO:0035926	chemokine (C-C motif) ligand 2 secretion	5.724153e-4
GO:0043311	positive regulation of eosinophil degranulation	5.724153e-4
GO:0007155	cell adhesion	6.040736e-4
GO:0034501	protein localization to kinetochore	6.060630e-4
GO:0070071	proton-transporting two-sector ATPase complex assembly	6.079567e-4
GO:0035966	response to topologically incorrect protein	6.108158e-4
GO:0006022	aminoglycan metabolic process	6.108158e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	6.204037e-4
GO:0035372	protein localization to microtubule	6.240948e-4
GO:0050930	induction of positive chemotaxis	6.301357e-4
GO:0032462	regulation of protein homooligomerization	6.303616e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	6.567847e-4
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	6.576729e-4
GO:0045401	positive regulation of interleukin-3 biosynthetic process	6.576729e-4
GO:0009750	response to fructose stimulus	6.805977e-4
GO:0006434	seryl-tRNA aminoacylation	6.867327e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	6.968437e-4
GO:0070536	protein K63-linked deubiquitination	7.025512e-4
GO:0003215	cardiac right ventricle morphogenesis	7.086570e-4
GO:0048840	otolith development	7.349789e-4
GO:0022407	regulation of cell-cell adhesion	7.538304e-4
GO:0022610	biological adhesion	7.787373e-4
GO:0051298	centrosome duplication	7.831550e-4
GO:0072190	ureter urothelium development	7.982572e-4
GO:0071174	mitotic cell cycle spindle checkpoint	7.982572e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	8.017976e-4
GO:0060373	regulation of ventricular cardiomyocyte membrane depolarization	8.017976e-4
GO:0034227	tRNA thio-modification	8.017976e-4
GO:0061364	apoptosis involved in luteolysis	8.860910e-4
GO:0007040	lysosome organization	9.138433e-4
GO:0060554	induction of necroptosis of activated-T cells	9.167016e-4
GO:0042628	mating plug formation	1.003175e-3
GO:0006915	apoptosis	1.019162e-3
GO:0042110	T cell activation	1.026776e-3
GO:0002312	B cell activation involved in immune response	1.031230e-3
GO:0022408	negative regulation of cell-cell adhesion	1.042743e-3
GO:0042176	regulation of protein catabolic process	1.063954e-3
GO:0031016	pancreas development	1.077109e-3
GO:0045090	retroviral genome replication	1.111225e-3
GO:0071712	ER-associated misfolded protein catabolic process	1.125499e-3
GO:0006302	double-strand break repair	1.129004e-3
GO:0030502	negative regulation of bone mineralization	1.159247e-3
GO:0032011	ARF protein signal transduction	1.161993e-3
GO:0072573	tolerance induction to lipopolysaccharide	1.175341e-3
GO:2000349	negative regulation of CD40 signaling pathway	1.175341e-3
GO:0002632	negative regulation of granuloma formation	1.175341e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.175341e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.175341e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.175341e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	1.179120e-3
GO:0009566	fertilization	1.202178e-3
GO:0022010	central nervous system myelination	1.218438e-3
GO:0030203	glycosaminoglycan metabolic process	1.238425e-3
GO:0031400	negative regulation of protein modification process	1.254796e-3
GO:0072560	type B pancreatic cell maturation	1.282963e-3
GO:0051142	positive regulation of NK T cell proliferation	1.282963e-3
GO:0070168	negative regulation of biomineral tissue development	1.350125e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.382937e-3
GO:0070537	histone H2A K63-linked deubiquitination	1.382937e-3
GO:0006709	progesterone catabolic process	1.545983e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.554899e-3
GO:0002507	tolerance induction	1.562468e-3
GO:0022409	positive regulation of cell-cell adhesion	1.650794e-3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	1.662456e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	1.665855e-3
GO:2000347	positive regulation of hepatocyte proliferation	1.682314e-3
GO:0032713	negative regulation of interleukin-4 production	1.708254e-3
GO:0018209	peptidyl-serine modification	1.728836e-3
GO:0006043	glucosamine catabolic process	1.740395e-3
GO:0071472	cellular response to salt stress	1.743234e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.743234e-3
GO:0007052	mitotic spindle organization	1.799502e-3
GO:0006260	DNA replication	1.815078e-3
GO:0032692	negative regulation of interleukin-1 production	1.822860e-3
GO:0005513	detection of calcium ion	1.885100e-3
GO:0007567	parturition	1.885100e-3
GO:2000657	negative regulation of apolipoprotein binding	1.887677e-3
GO:0048047	mating behavior, sex discrimination	1.887677e-3
GO:0001309	age-dependent telomere shortening	1.887677e-3
GO:0002124	territorial aggressive behavior	1.887677e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	1.887677e-3
GO:0002098	tRNA wobble uridine modification	1.919361e-3
GO:0046676	negative regulation of insulin secretion	1.986822e-3
GO:0016265	death	2.011414e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.028686e-3
GO:0034383	low-density lipoprotein particle clearance	2.057397e-3
GO:0031348	negative regulation of defense response	2.057581e-3
GO:0090076	relaxation of skeletal muscle	2.106662e-3
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.106662e-3
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.106662e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	2.106662e-3
GO:0045732	positive regulation of protein catabolic process	2.109137e-3
GO:0012501	programmed cell death	2.193574e-3
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	2.231103e-3
GO:0071777	positive regulation of cell cycle cytokinesis	2.234462e-3
GO:0000239	pachytene	2.286345e-3
GO:2000778	positive regulation of interleukin-6 secretion	2.299704e-3
GO:0007019	microtubule depolymerization	2.299704e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.348177e-3
GO:0033365	protein localization to organelle	2.393298e-3
GO:0019321	pentose metabolic process	2.397070e-3
GO:0042574	retinal metabolic process	2.456489e-3
GO:0030917	midbrain-hindbrain boundary development	2.501579e-3
GO:0051048	negative regulation of secretion	2.519731e-3
GO:0018393	internal peptidyl-lysine acetylation	2.527271e-3
GO:0043523	regulation of neuron apoptosis	2.543863e-3
GO:0022616	DNA strand elongation	2.578506e-3
GO:2000124	regulation of endocannabinoid signaling pathway	2.578506e-3
GO:0045321	leukocyte activation	2.581929e-3
GO:0007098	centrosome cycle	2.602011e-3
GO:0032463	negative regulation of protein homooligomerization	2.610852e-3
GO:0014819	regulation of skeletal muscle contraction	2.665665e-3
GO:0032094	response to food	2.710862e-3
GO:0018394	peptidyl-lysine acetylation	2.783240e-3
GO:0007519	skeletal muscle tissue development	2.851158e-3
GO:0043302	positive regulation of leukocyte degranulation	2.853385e-3
GO:0032817	regulation of natural killer cell proliferation	2.873743e-3
GO:0032465	regulation of cytokinesis	2.906614e-3
GO:2000256	positive regulation of male germ cell proliferation	2.931989e-3
GO:0042231	interleukin-13 biosynthetic process	2.931989e-3
GO:0090278	negative regulation of peptide hormone secretion	2.937478e-3
GO:0019853	L-ascorbic acid biosynthetic process	2.952859e-3
GO:0008219	cell death	2.968935e-3
GO:0005997	xylulose metabolic process	2.971369e-3
GO:0032691	negative regulation of interleukin-1 beta production	2.999562e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	3.000228e-3
GO:0070193	synaptonemal complex organization	3.000228e-3
GO:0002285	lymphocyte activation involved in immune response	3.023148e-3
GO:0071173	spindle assembly checkpoint	3.204655e-3
GO:2000348	regulation of CD40 signaling pathway	3.204655e-3
GO:0070936	protein K48-linked ubiquitination	3.255563e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	3.278671e-3
GO:0050727	regulation of inflammatory response	3.375057e-3
GO:0060100	positive regulation of phagocytosis, engulfment	3.446701e-3
GO:0009586	rhodopsin mediated phototransduction	3.446701e-3
GO:0030879	mammary gland development	3.466085e-3
GO:0044003	modification by symbiont of host morphology or physiology	3.518200e-3
GO:0034122	negative regulation of toll-like receptor signaling pathway	3.577478e-3
GO:0046649	lymphocyte activation	3.596515e-3
GO:0001754	eye photoreceptor cell differentiation	3.613228e-3
GO:0032232	negative regulation of actin filament bundle assembly	3.667716e-3
GO:0045602	negative regulation of endothelial cell differentiation	3.670896e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	3.670896e-3
GO:0048389	intermediate mesoderm development	3.670896e-3
GO:0043402	glucocorticoid mediated signaling pathway	3.670896e-3
GO:0032425	positive regulation of mismatch repair	3.670896e-3
GO:0061113	pancreas morphogenesis	3.673283e-3
GO:0006475	internal protein amino acid acetylation	3.737598e-3
GO:0042095	interferon-gamma biosynthetic process	3.765551e-3
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	3.765551e-3
GO:0015889	cobalamin transport	3.765551e-3
GO:0072012	glomerulus vasculature development	3.831357e-3
GO:0045824	negative regulation of innate immune response	3.831357e-3
GO:0033085	negative regulation of T cell differentiation in thymus	3.840474e-3
GO:0042953	lipoprotein transport	3.861818e-3
GO:0002315	marginal zone B cell differentiation	3.898282e-3
GO:0010754	negative regulation of cGMP-mediated signaling	3.939741e-3
GO:0010751	negative regulation of nitric oxide mediated signal transduction	3.939741e-3
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.939741e-3
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	3.939741e-3
GO:0042759	long-chain fatty acid biosynthetic process	4.175570e-3
GO:0048478	replication fork protection	4.269684e-3
GO:0042851	L-alanine metabolic process	4.269684e-3
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	4.285826e-3
GO:0071476	cellular hypotonic response	4.325944e-3
GO:0001554	luteolysis	4.325944e-3
GO:0031122	cytoplasmic microtubule organization	4.381076e-3
GO:0003341	cilium movement	4.483070e-3
GO:0070059	apoptosis in response to endoplasmic reticulum stress	4.499691e-3
GO:0060965	negative regulation of gene silencing by miRNA	4.516415e-3
GO:0000244	assembly of spliceosomal tri-snRNP	4.516415e-3
GO:0019464	glycine decarboxylation via glycine cleavage system	4.516415e-3
GO:0034629	cellular protein complex localization	4.569565e-3
GO:0042098	T cell proliferation	4.629592e-3
GO:0097028	dendritic cell differentiation	4.692020e-3
GO:0000189	MAPK import into nucleus	4.692020e-3
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	4.692020e-3
GO:0060414	aorta smooth muscle tissue morphogenesis	4.702322e-3
GO:0048846	axon extension involved in axon guidance	4.702322e-3
GO:0060538	skeletal muscle organ development	4.716344e-3
GO:0042384	cilium assembly	4.728572e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	4.734883e-3
GO:0003161	cardiac conduction system development	4.738285e-3
GO:0035413	positive regulation of catenin import into nucleus	4.928230e-3
GO:0070542	response to fatty acid	5.016745e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	5.060142e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	5.060142e-3
GO:0071874	cellular response to norepinephrine stimulus	5.075088e-3
GO:0006528	asparagine metabolic process	5.075088e-3
GO:0048844	artery morphogenesis	5.075911e-3
GO:0010749	regulation of nitric oxide mediated signal transduction	5.079624e-3
GO:0032930	positive regulation of superoxide anion generation	5.079624e-3
GO:0009791	post-embryonic development	5.141303e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	5.338715e-3
GO:0006505	GPI anchor metabolic process	5.438734e-3
GO:0032459	regulation of protein oligomerization	5.520578e-3
GO:0006029	proteoglycan metabolic process	5.620949e-3
GO:0031577	spindle checkpoint	5.627673e-3
GO:0043982	histone H4-K8 acetylation	5.732341e-3
GO:0043981	histone H4-K5 acetylation	5.732341e-3
GO:0030500	regulation of bone mineralization	5.739616e-3
GO:0046530	photoreceptor cell differentiation	5.742772e-3
GO:0060285	ciliary cell motility	5.878349e-3
GO:0032347	regulation of aldosterone biosynthetic process	5.878349e-3
GO:0043309	regulation of eosinophil degranulation	5.921986e-3
GO:0097029	mature dendritic cell differentiation	5.921986e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	6.000148e-3
GO:2000543	positive regulation of gastrulation	6.139314e-3
GO:0007635	chemosensory behavior	6.139314e-3
GO:0021903	rostrocaudal neural tube patterning	6.232556e-3
GO:0051276	chromosome organization	6.508845e-3
GO:0032467	positive regulation of cytokinesis	6.543766e-3
GO:0007160	cell-matrix adhesion	6.554402e-3
GO:0030217	T cell differentiation	6.588892e-3
GO:0035644	phosphoanandamide dephosphorylation	6.785340e-3
GO:0010757	negative regulation of plasminogen activation	6.844614e-3
GO:0030858	positive regulation of epithelial cell differentiation	6.882808e-3
GO:0050850	positive regulation of calcium-mediated signaling	6.965286e-3
GO:0009083	branched chain family amino acid catabolic process	6.970603e-3
GO:0032349	positive regulation of aldosterone biosynthetic process	6.978598e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	7.082847e-3
GO:0060252	positive regulation of glial cell proliferation	7.217987e-3
GO:0043652	engulfment of apoptotic cell	7.217987e-3
GO:0070509	calcium ion import	7.250656e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	7.267574e-3
GO:0050709	negative regulation of protein secretion	7.306872e-3
GO:0045087	innate immune response	7.328704e-3
GO:0030521	androgen receptor signaling pathway	7.428382e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	7.485145e-3
GO:0050810	regulation of steroid biosynthetic process	7.511360e-3
GO:0070933	histone H4 deacetylation	7.525331e-3
GO:0001556	oocyte maturation	7.620841e-3
GO:0055007	cardiac muscle cell differentiation	7.740462e-3
GO:0019236	response to pheromone	7.906191e-3
GO:0045190	isotype switching	7.957647e-3
GO:0035304	regulation of protein dephosphorylation	7.957647e-3
GO:0070167	regulation of biomineral tissue development	7.998664e-3
GO:0072162	metanephric mesenchymal cell differentiation	8.056729e-3
GO:0051029	rRNA transport	8.056729e-3
GO:0046898	response to cycloheximide	8.056729e-3
GO:0051224	negative regulation of protein transport	8.073386e-3
GO:0002634	regulation of germinal center formation	8.121379e-3
GO:0002011	morphogenesis of an epithelial sheet	8.148010e-3
GO:0051225	spindle assembly	8.177483e-3
GO:0045409	negative regulation of interleukin-6 biosynthetic process	8.254767e-3
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	8.254767e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	8.355797e-3
GO:0060426	lung vasculature development	8.362156e-3
GO:0045768	positive regulation of anti-apoptosis	8.408344e-3
GO:0055001	muscle cell development	8.424471e-3
GO:0007126	meiosis	8.447784e-3
GO:2000345	regulation of hepatocyte proliferation	8.545281e-3
GO:0031647	regulation of protein stability	8.621748e-3
GO:0006418	tRNA aminoacylation for protein translation	8.656005e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	8.796925e-3
GO:0060112	generation of ovulation cycle rhythm	8.796925e-3
GO:0050864	regulation of B cell activation	8.805908e-3
GO:0002792	negative regulation of peptide secretion	8.872322e-3
GO:0071218	cellular response to misfolded protein	8.884227e-3
GO:0055069	zinc ion homeostasis	8.951210e-3
GO:0007129	synapsis	8.951210e-3
GO:0060931	sinoatrial node cell development	8.963242e-3
GO:0003167	atrioventricular bundle cell differentiation	8.963242e-3
GO:0034114	regulation of heterotypic cell-cell adhesion	8.998022e-3
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	8.998022e-3
GO:0070661	leukocyte proliferation	9.001873e-3
GO:0045767	regulation of anti-apoptosis	9.020395e-3
GO:0006270	DNA-dependent DNA replication initiation	9.034883e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	9.034883e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	9.204764e-3
GO:0008228	opsonization	9.243745e-3
GO:0000226	microtubule cytoskeleton organization	9.740073e-3
GO:0043631	RNA polyadenylation	9.744810e-3
GO:0072239	metanephric glomerulus vasculature development	9.867628e-3
GO:0045217	cell-cell junction maintenance	9.867628e-3
GO:0046929	negative regulation of neurotransmitter secretion	9.899393e-3
GO:0043547	positive regulation of GTPase activity	9.910494e-3
GO:0002455	humoral immune response mediated by circulating immunoglobulin	9.957269e-3
GO:0035308	negative regulation of protein dephosphorylation	9.983849e-3
GO:0000012	single strand break repair	9.983849e-3
GO:0051583	dopamine uptake	1.008507e-2
GO:0090030	regulation of steroid hormone biosynthetic process	1.022813e-2
GO:0043134	regulation of hindgut contraction	1.023602e-2
GO:0032602	chemokine production	1.023602e-2
GO:0003417	growth plate cartilage development	1.027402e-2
GO:2000379	positive regulation of reactive oxygen species metabolic process	1.059918e-2
GO:0018205	peptidyl-lysine modification	1.061894e-2
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.075494e-2
GO:0003323	type B pancreatic cell development	1.075494e-2
GO:0030223	neutrophil differentiation	1.075494e-2
GO:0034201	response to oleic acid	1.076702e-2
GO:0070192	chromosome organization involved in meiosis	1.093061e-2
GO:0016573	histone acetylation	1.093182e-2
GO:0007603	phototransduction, visible light	1.099082e-2
GO:0001955	blood vessel maturation	1.099082e-2
GO:0006917	induction of apoptosis	1.099842e-2
GO:0070925	organelle assembly	1.115124e-2
GO:0035909	aorta morphogenesis	1.128413e-2
GO:0090185	negative regulation of kidney development	1.139254e-2
GO:0021993	initiation of neural tube closure	1.139254e-2
GO:0042116	macrophage activation	1.147483e-2
GO:0042036	negative regulation of cytokine biosynthetic process	1.149278e-2
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.159466e-2
GO:0071870	cellular response to catecholamine stimulus	1.159466e-2
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1.159466e-2
GO:0072133	metanephric mesenchyme morphogenesis	1.161648e-2
GO:0019543	propionate catabolic process	1.161648e-2
GO:0050908	detection of light stimulus involved in visual perception	1.169872e-2
GO:0034143	regulation of toll-like receptor 4 signaling pathway	1.179529e-2
GO:0003007	heart morphogenesis	1.187841e-2
GO:0051321	meiotic cell cycle	1.208943e-2
GO:0000819	sister chromatid segregation	1.230519e-2
GO:0046685	response to arsenic-containing substance	1.233931e-2
GO:0090103	cochlea morphogenesis	1.246743e-2
GO:0012502	induction of programmed cell death	1.261028e-2
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.262598e-2
GO:2000178	negative regulation of neural precursor cell proliferation	1.268026e-2
GO:0020028	hemoglobin import	1.281072e-2
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.281072e-2
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1.292194e-2
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.292194e-2
GO:0060376	positive regulation of mast cell differentiation	1.292194e-2
GO:0002508	central tolerance induction	1.292194e-2
GO:0009589	detection of UV	1.292194e-2
GO:0002897	positive regulation of central B cell tolerance induction	1.292194e-2
GO:0043535	regulation of blood vessel endothelial cell migration	1.303069e-2
GO:0045408	regulation of interleukin-6 biosynthetic process	1.315021e-2
GO:0021984	adenohypophysis development	1.315021e-2
GO:0001922	B-1 B cell homeostasis	1.315021e-2
GO:0006261	DNA-dependent DNA replication	1.317250e-2
GO:0007141	male meiosis I	1.338899e-2
GO:0009235	cobalamin metabolic process	1.351353e-2
GO:0006925	inflammatory cell apoptosis	1.351353e-2
GO:0030857	negative regulation of epithelial cell differentiation	1.368396e-2
GO:0070979	protein K11-linked ubiquitination	1.372451e-2
GO:0010755	regulation of plasminogen activation	1.376325e-2
GO:0009081	branched chain family amino acid metabolic process	1.386409e-2
GO:0071310	cellular response to organic substance	1.420016e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.427993e-2
GO:0003327	type B pancreatic cell fate commitment	1.427993e-2
GO:0010884	positive regulation of lipid storage	1.433207e-2
GO:0060312	regulation of blood vessel remodeling	1.434349e-2
GO:0002698	negative regulation of immune effector process	1.445544e-2
GO:0016032	viral reproduction	1.452002e-2
GO:0021592	fourth ventricle development	1.460923e-2
GO:0002376	immune system process	1.475589e-2
GO:0060445	branching involved in salivary gland morphogenesis	1.477365e-2
GO:0010159	specification of organ position	1.488770e-2
GO:2000352	negative regulation of endothelial cell apoptosis	1.539936e-2
GO:0046666	retinal cell programmed cell death	1.559639e-2
GO:0033345	asparagine catabolic process via L-aspartate	1.559639e-2
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	1.559639e-2
GO:0006312	mitotic recombination	1.559639e-2
GO:0030330	DNA damage response, signal transduction by p53 class mediator	1.561313e-2
GO:0010470	regulation of gastrulation	1.574166e-2
GO:0019048	virus-host interaction	1.585573e-2
GO:0051248	negative regulation of protein metabolic process	1.594929e-2
GO:0071727	cellular response to triacyl bacterial lipopeptide	1.597145e-2
GO:0060971	embryonic heart tube left/right pattern formation	1.597145e-2
GO:0090045	positive regulation of deacetylase activity	1.597145e-2
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	1.597145e-2
GO:0042495	detection of triacyl bacterial lipopeptide	1.597145e-2
GO:0042938	dipeptide transport	1.597145e-2
GO:0060921	sinoatrial node cell differentiation	1.597961e-2
GO:0047496	vesicle transport along microtubule	1.597961e-2
GO:0048294	negative regulation of isotype switching to IgE isotypes	1.607599e-2
GO:0043966	histone H3 acetylation	1.614535e-2
GO:0060134	prepulse inhibition	1.620969e-2
GO:0032673	regulation of interleukin-4 production	1.629867e-2
GO:0046488	phosphatidylinositol metabolic process	1.635253e-2
GO:0042035	regulation of cytokine biosynthetic process	1.644874e-2
GO:0001569	patterning of blood vessels	1.648391e-2
GO:0034121	regulation of toll-like receptor signaling pathway	1.661719e-2
GO:0090276	regulation of peptide hormone secretion	1.709140e-2
GO:0050796	regulation of insulin secretion	1.711640e-2
GO:0032101	regulation of response to external stimulus	1.715760e-2
GO:0046651	lymphocyte proliferation	1.725711e-2
GO:0018108	peptidyl-tyrosine phosphorylation	1.728644e-2
GO:0015937	coenzyme A biosynthetic process	1.732989e-2
GO:0072143	mesangial cell development	1.743622e-2
GO:0090273	regulation of somatostatin secretion	1.757233e-2
GO:0007262	STAT protein import into nucleus	1.757233e-2
GO:0071374	cellular response to parathyroid hormone stimulus	1.757233e-2
GO:2000172	regulation of branching morphogenesis of a nerve	1.776728e-2
GO:0030967	ER-nuclear sterol response pathway	1.776728e-2
GO:0010624	regulation of Schwann cell proliferation	1.776728e-2
GO:0019541	propionate metabolic process	1.787027e-2
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.790294e-2
GO:0019852	L-ascorbic acid metabolic process	1.820388e-2
GO:0050777	negative regulation of immune response	1.837119e-2
GO:0043687	post-translational protein modification	1.874986e-2
GO:0046825	regulation of protein export from nucleus	1.893370e-2
GO:0060926	pacemaker cell development	1.898136e-2
GO:0060932	His-Purkinje system cell differentiation	1.898136e-2
GO:0006474	N-terminal protein amino acid acetylation	1.898136e-2