Novel motif:24

name:	motif24_AGAACT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	4.009464e-31
GO:0006952	defense response	2.521652e-26
GO:0051716	cellular response to stimulus	1.782302e-23
GO:0007165	signal transduction	5.847529e-22
GO:0002376	immune system process	2.688806e-20
GO:0006950	response to stress	6.852033e-18
GO:0002684	positive regulation of immune system process	1.407509e-17
GO:0023052	signaling	1.409427e-17
GO:0050776	regulation of immune response	1.202762e-16
GO:0051704	multi-organism process	1.000204e-15
GO:0002697	regulation of immune effector process	1.695142e-15
GO:0009611	response to wounding	1.771248e-15
GO:0007166	cell surface receptor linked signaling pathway	3.126810e-15
GO:0051707	response to other organism	3.938528e-15
GO:0045087	innate immune response	4.230931e-15
GO:0007154	cell communication	7.650626e-15
GO:0050778	positive regulation of immune response	7.934593e-15
GO:0006955	immune response	1.683802e-14
GO:0006954	inflammatory response	6.009832e-14
GO:0009607	response to biotic stimulus	1.146968e-13
GO:0002682	regulation of immune system process	1.817365e-13
GO:0032675	regulation of interleukin-6 production	2.162795e-13
GO:0002253	activation of immune response	3.741575e-13
GO:0002694	regulation of leukocyte activation	4.943230e-13
GO:0042221	response to chemical stimulus	5.804271e-13
GO:0002764	immune response-regulating signaling pathway	6.142081e-13
GO:0019538	protein metabolic process	8.298669e-13
GO:0009617	response to bacterium	9.648901e-13
GO:0051249	regulation of lymphocyte activation	9.699867e-13
GO:0031349	positive regulation of defense response	1.384495e-12
GO:0002757	immune response-activating signal transduction	1.886535e-12
GO:0051384	response to glucocorticoid stimulus	4.340190e-12
GO:0032755	positive regulation of interleukin-6 production	5.223567e-12
GO:0050865	regulation of cell activation	6.866255e-12
GO:0014041	regulation of neuron maturation	7.341109e-12
GO:0019441	tryptophan catabolic process to kynurenine	1.210660e-11
GO:0045137	development of primary sexual characteristics	1.356985e-11
GO:0042742	defense response to bacterium	1.411454e-11
GO:0045088	regulation of innate immune response	1.812311e-11
GO:0042325	regulation of phosphorylation	2.648889e-11
GO:0007548	sex differentiation	4.191779e-11
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	4.807457e-11
GO:0048608	reproductive structure development	4.825922e-11
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	4.871845e-11
GO:0051046	regulation of secretion	6.521357e-11
GO:0050794	regulation of cellular process	7.276498e-11
GO:0002696	positive regulation of leukocyte activation	8.898915e-11
GO:0019220	regulation of phosphate metabolic process	1.006109e-10
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.018968e-10
GO:0051251	positive regulation of lymphocyte activation	1.066623e-10
GO:0044267	cellular protein metabolic process	1.459563e-10
GO:0045624	positive regulation of T-helper cell differentiation	1.510011e-10
GO:0045089	positive regulation of innate immune response	1.513053e-10
GO:0045622	regulation of T-helper cell differentiation	1.638725e-10
GO:0060341	regulation of cellular localization	1.642824e-10
GO:0001775	cell activation	2.361397e-10
GO:0046661	male sex differentiation	2.770287e-10
GO:0034329	cell junction assembly	3.220511e-10
GO:0008406	gonad development	3.528524e-10
GO:0046637	regulation of alpha-beta T cell differentiation	4.678215e-10
GO:0031960	response to corticosteroid stimulus	5.598295e-10
GO:0019046	reactivation of latent virus	5.928504e-10
GO:0034341	response to interferon-gamma	6.287682e-10
GO:0070189	kynurenine metabolic process	6.308277e-10
GO:0034330	cell junction organization	9.183612e-10
GO:0050867	positive regulation of cell activation	1.119702e-9
GO:0031347	regulation of defense response	1.127699e-9
GO:0046635	positive regulation of alpha-beta T cell activation	1.204133e-9
GO:0001932	regulation of protein phosphorylation	1.268968e-9
GO:0006508	proteolysis	1.453817e-9
GO:0051179	localization	2.032177e-9
GO:0046638	positive regulation of alpha-beta T cell differentiation	2.155889e-9
GO:0046546	development of primary male sexual characteristics	2.354755e-9
GO:0009100	glycoprotein metabolic process	2.744394e-9
GO:0048583	regulation of response to stimulus	3.273378e-9
GO:0002218	activation of innate immune response	3.467375e-9
GO:0002237	response to molecule of bacterial origin	3.848769e-9
GO:0001817	regulation of cytokine production	4.104649e-9
GO:0045628	regulation of T-helper 2 cell differentiation	5.434514e-9
GO:0043170	macromolecule metabolic process	6.310025e-9
GO:0043004	cytoplasmic sequestering of CFTR protein	7.083046e-9
GO:0032496	response to lipopolysaccharide	9.797049e-9
GO:0050870	positive regulation of T cell activation	1.116789e-8
GO:0051050	positive regulation of transport	1.257702e-8
GO:0051023	regulation of immunoglobulin secretion	1.279127e-8
GO:0034097	response to cytokine stimulus	1.382647e-8
GO:0046634	regulation of alpha-beta T cell activation	1.391084e-8
GO:0065007	biological regulation	1.622709e-8
GO:0051049	regulation of transport	1.642803e-8
GO:0070887	cellular response to chemical stimulus	1.745821e-8
GO:0050830	defense response to Gram-positive bacterium	1.781936e-8
GO:0030216	keratinocyte differentiation	1.805518e-8
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.862254e-8
GO:0032649	regulation of interferon-gamma production	2.130787e-8
GO:0014043	negative regulation of neuron maturation	2.270011e-8
GO:0008584	male gonad development	2.608691e-8
GO:0019359	nicotinamide nucleotide biosynthetic process	2.610799e-8
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	3.276252e-8
GO:0010033	response to organic substance	3.682635e-8
GO:0009435	NAD biosynthetic process	4.207475e-8
GO:0050789	regulation of biological process	4.595673e-8
GO:0046330	positive regulation of JNK cascade	4.742342e-8
GO:0080134	regulation of response to stress	5.119484e-8
GO:0002429	immune response-activating cell surface receptor signaling pathway	6.011236e-8
GO:0002825	regulation of T-helper 1 type immune response	6.782823e-8
GO:0001819	positive regulation of cytokine production	7.644866e-8
GO:0009101	glycoprotein biosynthetic process	7.742701e-8
GO:0031581	hemidesmosome assembly	7.897950e-8
GO:0016192	vesicle-mediated transport	8.231897e-8
GO:0045630	positive regulation of T-helper 2 cell differentiation	8.314146e-8
GO:0045621	positive regulation of lymphocyte differentiation	8.551063e-8
GO:0002819	regulation of adaptive immune response	8.920010e-8
GO:0001655	urogenital system development	8.926689e-8
GO:0006468	protein phosphorylation	9.923324e-8
GO:0007044	cell-substrate junction assembly	1.046852e-7
GO:0023051	regulation of signaling	1.111818e-7
GO:0050851	antigen receptor-mediated signaling pathway	1.115402e-7
GO:0050708	regulation of protein secretion	1.131920e-7
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.140665e-7
GO:0002758	innate immune response-activating signal transduction	1.141826e-7
GO:0032729	positive regulation of interferon-gamma production	1.194731e-7
GO:0048245	eosinophil chemotaxis	1.212103e-7
GO:0032879	regulation of localization	1.358822e-7
GO:0006569	tryptophan catabolic process	1.368026e-7
GO:0007018	microtubule-based movement	1.378763e-7
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.393542e-7
GO:0050930	induction of positive chemotaxis	1.504910e-7
GO:0002221	pattern recognition receptor signaling pathway	1.792698e-7
GO:0006568	tryptophan metabolic process	1.993465e-7
GO:0044257	cellular protein catabolic process	2.098763e-7
GO:2000348	regulation of CD40 signaling pathway	2.137192e-7
GO:0046660	female sex differentiation	2.184384e-7
GO:0090084	negative regulation of inclusion body assembly	2.369212e-7
GO:0051607	defense response to virus	2.407276e-7
GO:0032663	regulation of interleukin-2 production	2.407276e-7
GO:0031424	keratinization	2.506760e-7
GO:0006464	protein modification process	2.526138e-7
GO:0007186	G-protein coupled receptor protein signaling pathway	2.770082e-7
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	2.889968e-7
GO:0016337	cell-cell adhesion	3.056841e-7
GO:0031110	regulation of microtubule polymerization or depolymerization	3.072519e-7
GO:0030855	epithelial cell differentiation	3.134662e-7
GO:0009888	tissue development	3.211309e-7
GO:0072001	renal system development	3.446237e-7
GO:0051188	cofactor biosynthetic process	3.582173e-7
GO:0048935	peripheral nervous system neuron development	3.643811e-7
GO:0016101	diterpenoid metabolic process	3.743713e-7
GO:0071219	cellular response to molecule of bacterial origin	3.767243e-7
GO:0042904	9-cis-retinoic acid biosynthetic process	3.768285e-7
GO:0006968	cellular defense response	3.815269e-7
GO:0000278	mitotic cell cycle	4.016790e-7
GO:0009913	epidermal cell differentiation	4.064489e-7
GO:0051902	negative regulation of mitochondrial depolarization	4.621918e-7
GO:0048015	phosphatidylinositol-mediated signaling	4.713173e-7
GO:0002828	regulation of type 2 immune response	5.077757e-7
GO:0051603	proteolysis involved in cellular protein catabolic process	5.131099e-7
GO:0050863	regulation of T cell activation	5.132719e-7
GO:0035556	intracellular signal transduction	5.184607e-7
GO:0007155	cell adhesion	5.234153e-7
GO:0051047	positive regulation of secretion	5.409659e-7
GO:0048660	regulation of smooth muscle cell proliferation	5.572777e-7
GO:0002699	positive regulation of immune effector process	5.620187e-7
GO:0046545	development of primary female sexual characteristics	6.253689e-7
GO:0043632	modification-dependent macromolecule catabolic process	6.269383e-7
GO:0010982	regulation of high-density lipoprotein particle clearance	6.350912e-7
GO:0043412	macromolecule modification	6.478748e-7
GO:0006348	chromatin silencing at telomere	6.607829e-7
GO:0071844	cellular component assembly at cellular level	7.294647e-7
GO:0008544	epidermis development	7.325413e-7
GO:0071222	cellular response to lipopolysaccharide	7.683950e-7
GO:0051412	response to corticosterone stimulus	7.736126e-7
GO:0019941	modification-dependent protein catabolic process	7.759424e-7
GO:0032880	regulation of protein localization	8.027515e-7
GO:0065009	regulation of molecular function	8.161831e-7
GO:0048511	rhythmic process	8.608293e-7
GO:0045730	respiratory burst	9.034800e-7
GO:0044260	cellular macromolecule metabolic process	9.071112e-7
GO:0048566	embryonic digestive tract development	9.428212e-7
GO:0042445	hormone metabolic process	9.480682e-7
GO:0030031	cell projection assembly	9.691882e-7
GO:0034754	cellular hormone metabolic process	9.997431e-7
GO:0006887	exocytosis	1.023442e-6
GO:0050829	defense response to Gram-negative bacterium	1.023826e-6
GO:0048769	sarcomerogenesis	1.078540e-6
GO:0016310	phosphorylation	1.113447e-6
GO:0006511	ubiquitin-dependent protein catabolic process	1.143380e-6
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	1.155315e-6
GO:0009072	aromatic amino acid family metabolic process	1.236382e-6
GO:0050715	positive regulation of cytokine secretion	1.255374e-6
GO:0043420	anthranilate metabolic process	1.286882e-6
GO:0034516	response to vitamin B6	1.286882e-6
GO:0030241	skeletal muscle myosin thick filament assembly	1.322852e-6
GO:0002831	regulation of response to biotic stimulus	1.365032e-6
GO:0050714	positive regulation of protein secretion	1.380557e-6
GO:0010040	response to iron(II) ion	1.400703e-6
GO:0051641	cellular localization	1.447617e-6
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.464592e-6
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.464592e-6
GO:0008152	metabolic process	1.471629e-6
GO:0050729	positive regulation of inflammatory response	1.482029e-6
GO:0061043	regulation of vascular wound healing	1.548546e-6
GO:0006586	indolalkylamine metabolic process	1.577578e-6
GO:0043497	regulation of protein heterodimerization activity	1.644859e-6
GO:0032735	positive regulation of interleukin-12 production	1.650895e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	1.660289e-6
GO:0045582	positive regulation of T cell differentiation	1.860286e-6
GO:0006796	phosphate-containing compound metabolic process	1.886237e-6
GO:0008585	female gonad development	1.914680e-6
GO:0009966	regulation of signal transduction	1.991438e-6
GO:0008104	protein localization	2.005283e-6
GO:0051234	establishment of localization	2.062485e-6
GO:0050707	regulation of cytokine secretion	2.074155e-6
GO:0042996	regulation of Golgi to plasma membrane protein transport	2.086524e-6
GO:0001523	retinoid metabolic process	2.122478e-6
GO:0071346	cellular response to interferon-gamma	2.142081e-6
GO:2000345	regulation of hepatocyte proliferation	2.149850e-6
GO:0006447	regulation of translational initiation by iron	2.345099e-6
GO:0045623	negative regulation of T-helper cell differentiation	2.381153e-6
GO:0016199	axon midline choice point recognition	2.393423e-6
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2.459523e-6
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	2.471163e-6
GO:0048584	positive regulation of response to stimulus	2.498936e-6
GO:0019363	pyridine nucleotide biosynthetic process	2.499382e-6
GO:0051338	regulation of transferase activity	2.670323e-6
GO:0019674	NAD metabolic process	2.837377e-6
GO:0032330	regulation of chondrocyte differentiation	2.876467e-6
GO:0045625	regulation of T-helper 1 cell differentiation	2.899194e-6
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	2.920651e-6
GO:0044238	primary metabolic process	2.936671e-6
GO:0045069	regulation of viral genome replication	2.983826e-6
GO:0022607	cellular component assembly	2.994734e-6
GO:0032467	positive regulation of cytokinesis	3.147182e-6
GO:0032501	multicellular organismal process	3.172518e-6
GO:0043549	regulation of kinase activity	3.199509e-6
GO:0018874	benzoate metabolic process	3.282684e-6
GO:0044070	regulation of anion transport	3.417782e-6
GO:0060409	positive regulation of acetylcholine metabolic process	3.445571e-6
GO:0051223	regulation of protein transport	3.449394e-6
GO:0045626	negative regulation of T-helper 1 cell differentiation	3.455275e-6
GO:0010817	regulation of hormone levels	3.472791e-6
GO:0007156	homophilic cell adhesion	3.514420e-6
GO:0050864	regulation of B cell activation	3.609980e-6
GO:0042384	cilium assembly	3.662400e-6
GO:0010741	negative regulation of intracellular protein kinase cascade	3.925749e-6
GO:0048857	neural nucleus development	4.278920e-6
GO:2000351	regulation of endothelial cell apoptosis	4.315488e-6
GO:0070201	regulation of establishment of protein localization	4.476960e-6
GO:0015827	tryptophan transport	4.667265e-6
GO:0050790	regulation of catalytic activity	4.778661e-6
GO:0043269	regulation of ion transport	4.804251e-6
GO:0045321	leukocyte activation	4.844825e-6
GO:0010627	regulation of intracellular protein kinase cascade	4.868587e-6
GO:0065008	regulation of biological quality	5.418000e-6
GO:0001656	metanephros development	5.729010e-6
GO:0061039	ovum-producing ovary development	5.835043e-6
GO:0050691	regulation of defense response to virus by host	5.844217e-6
GO:0050727	regulation of inflammatory response	6.062985e-6
GO:0030163	protein catabolic process	6.276262e-6
GO:0042060	wound healing	6.495663e-6
GO:0042574	retinal metabolic process	6.807200e-6
GO:0044093	positive regulation of molecular function	6.870855e-6
GO:0007049	cell cycle	7.000813e-6
GO:0045994	positive regulation of translational initiation by iron	7.356632e-6
GO:0002037	negative regulation of L-glutamate transport	7.356632e-6
GO:0043550	regulation of lipid kinase activity	8.370661e-6
GO:0006810	transport	8.443863e-6
GO:0050673	epithelial cell proliferation	8.473150e-6
GO:0007264	small GTPase mediated signal transduction	8.497698e-6
GO:0048513	organ development	8.606514e-6
GO:0000165	MAPKKK cascade	8.860766e-6
GO:0006928	cellular component movement	9.232764e-6
GO:0022402	cell cycle process	9.314600e-6
GO:0061035	regulation of cartilage development	9.416914e-6
GO:0007076	mitotic chromosome condensation	9.789815e-6
GO:0016043	cellular component organization	1.002116e-5
GO:0045619	regulation of lymphocyte differentiation	1.030734e-5
GO:0019722	calcium-mediated signaling	1.033484e-5
GO:0032825	positive regulation of natural killer cell differentiation	1.044517e-5
GO:0002224	toll-like receptor signaling pathway	1.059729e-5
GO:0009108	coenzyme biosynthetic process	1.086764e-5
GO:0051222	positive regulation of protein transport	1.102145e-5
GO:0032495	response to muramyl dipeptide	1.138072e-5
GO:0001822	kidney development	1.233486e-5
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.240774e-5
GO:0006875	cellular metal ion homeostasis	1.274490e-5
GO:0055065	metal ion homeostasis	1.296567e-5
GO:0008209	androgen metabolic process	1.308914e-5
GO:0007173	epidermal growth factor receptor signaling pathway	1.338236e-5
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.377192e-5
GO:0016265	death	1.389933e-5
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.412421e-5
GO:0016044	cellular membrane organization	1.419179e-5
GO:0051250	negative regulation of lymphocyte activation	1.495646e-5
GO:0032494	response to peptidoglycan	1.533755e-5
GO:0014065	phosphatidylinositol 3-kinase cascade	1.548262e-5
GO:0022403	cell cycle phase	1.551244e-5
GO:0034139	regulation of toll-like receptor 3 signaling pathway	1.579924e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.623577e-5
GO:0010897	negative regulation of triglyceride catabolic process	1.623577e-5
GO:0043331	response to dsRNA	1.628553e-5
GO:0009987	cellular process	1.672740e-5
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	1.700984e-5
GO:0046883	regulation of hormone secretion	1.723839e-5
GO:0007043	cell-cell junction assembly	1.735086e-5
GO:0061024	membrane organization	1.739531e-5
GO:0070663	regulation of leukocyte proliferation	1.740346e-5
GO:0046649	lymphocyte activation	1.740470e-5
GO:0071840	cellular component organization or biogenesis	1.752115e-5
GO:0043408	regulation of MAPKKK cascade	1.770339e-5
GO:0009181	purine ribonucleoside diphosphate catabolic process	1.772441e-5
GO:0072573	tolerance induction to lipopolysaccharide	1.782266e-5
GO:2000347	positive regulation of hepatocyte proliferation	1.782266e-5
GO:2000349	negative regulation of CD40 signaling pathway	1.782266e-5
GO:0090291	negative regulation of osteoclast proliferation	1.782266e-5
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.782266e-5
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.782266e-5
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.782266e-5
GO:0009074	aromatic amino acid family catabolic process	1.829019e-5
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	1.836988e-5
GO:0006436	tryptophanyl-tRNA aminoacylation	1.843088e-5
GO:0032653	regulation of interleukin-10 production	1.859196e-5
GO:0008219	cell death	1.887953e-5
GO:0043623	cellular protein complex assembly	1.916920e-5
GO:0006915	apoptosis	1.976004e-5
GO:0002252	immune effector process	2.039353e-5
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	2.044632e-5
GO:0050688	regulation of defense response to virus	2.059979e-5
GO:0001101	response to acid	2.210636e-5
GO:0050852	T cell receptor signaling pathway	2.245993e-5
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	2.279341e-5
GO:0034121	regulation of toll-like receptor signaling pathway	2.294224e-5
GO:0050900	leukocyte migration	2.312570e-5
GO:2000612	regulation of thyroid-stimulating hormone secretion	2.313369e-5
GO:0007026	negative regulation of microtubule depolymerization	2.314493e-5
GO:0051056	regulation of small GTPase mediated signal transduction	2.341641e-5
GO:0012501	programmed cell death	2.401406e-5
GO:0042345	regulation of NF-kappaB import into nucleus	2.461882e-5
GO:0044419	interspecies interaction between organisms	2.657081e-5
GO:0040017	positive regulation of locomotion	2.661157e-5
GO:0060675	ureteric bud morphogenesis	2.686259e-5
GO:0008283	cell proliferation	2.703369e-5
GO:0032103	positive regulation of response to external stimulus	2.830520e-5
GO:0000087	M phase of mitotic cell cycle	2.893941e-5
GO:0031114	regulation of microtubule depolymerization	2.922905e-5
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	2.959529e-5
GO:0006486	protein glycosylation	3.043085e-5
GO:0007497	posterior midgut development	3.112612e-5
GO:0048009	insulin-like growth factor receptor signaling pathway	3.137505e-5
GO:0033036	macromolecule localization	3.150831e-5
GO:0002576	platelet degranulation	3.235675e-5
GO:0070375	BMK cascade	3.283074e-5
GO:0016050	vesicle organization	3.293958e-5
GO:0051385	response to mineralocorticoid stimulus	3.295983e-5
GO:0050853	B cell receptor signaling pathway	3.312721e-5
GO:0016198	axon choice point recognition	3.343234e-5
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	3.402522e-5
GO:0001774	microglial cell activation	3.442429e-5
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	3.458677e-5
GO:0040007	growth	3.478077e-5
GO:0071216	cellular response to biotic stimulus	3.638946e-5
GO:0060627	regulation of vesicle-mediated transport	3.639007e-5
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	3.780837e-5
GO:0006776	vitamin A metabolic process	3.826758e-5
GO:0031341	regulation of cell killing	3.827717e-5
GO:0022602	ovulation cycle process	3.913730e-5
GO:0050927	positive regulation of positive chemotaxis	3.971678e-5
GO:0045006	DNA deamination	4.058413e-5
GO:0010466	negative regulation of peptidase activity	4.063326e-5
GO:0042698	ovulation cycle	4.249806e-5
GO:0035411	catenin import into nucleus	4.254126e-5
GO:0072503	cellular divalent inorganic cation homeostasis	4.303782e-5
GO:0048016	inositol phosphate-mediated signaling	4.309162e-5
GO:0016079	synaptic vesicle exocytosis	4.429449e-5
GO:0006721	terpenoid metabolic process	4.617995e-5
GO:0055003	cardiac myofibril assembly	4.642701e-5
GO:0043330	response to exogenous dsRNA	4.697745e-5
GO:0051649	establishment of localization in cell	4.708031e-5
GO:0001541	ovarian follicle development	4.807968e-5
GO:0045859	regulation of protein kinase activity	4.856267e-5
GO:0043410	positive regulation of MAPKKK cascade	4.859009e-5
GO:0009629	response to gravity	4.876547e-5
GO:0044237	cellular metabolic process	4.881250e-5
GO:0034135	regulation of toll-like receptor 2 signaling pathway	4.910381e-5
GO:2000352	negative regulation of endothelial cell apoptosis	5.059111e-5
GO:0019932	second-messenger-mediated signaling	5.292765e-5
GO:0002274	myeloid leukocyte activation	5.295958e-5
GO:0071777	positive regulation of cell cycle cytokinesis	5.319155e-5
GO:0035645	enteric smooth muscle cell differentiation	5.454946e-5
GO:0007067	mitosis	5.455145e-5
GO:0070085	glycosylation	5.465444e-5
GO:0051961	negative regulation of nervous system development	5.497899e-5
GO:0048806	genitalia development	5.609110e-5
GO:0001519	peptide amidation	5.623162e-5
GO:0031622	positive regulation of fever generation	5.710009e-5
GO:0007030	Golgi organization	5.737023e-5
GO:0014732	skeletal muscle atrophy	5.743793e-5
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	5.855374e-5
GO:0032848	negative regulation of cellular pH reduction	5.855374e-5
GO:0021747	cochlear nucleus development	5.855374e-5
GO:0014042	positive regulation of neuron maturation	5.855374e-5
GO:0035771	interleukin-4-mediated signaling pathway	5.882251e-5
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	5.944181e-5
GO:0048518	positive regulation of biological process	5.956324e-5
GO:0043900	regulation of multi-organism process	6.067562e-5
GO:0031399	regulation of protein modification process	6.075481e-5
GO:0042362	fat-soluble vitamin biosynthetic process	6.079152e-5
GO:0042116	macrophage activation	6.169883e-5
GO:0032940	secretion by cell	6.188020e-5
GO:0030335	positive regulation of cell migration	6.422098e-5
GO:0032854	positive regulation of Rap GTPase activity	6.513179e-5
GO:0043085	positive regulation of catalytic activity	6.533520e-5
GO:0050713	negative regulation of interleukin-1 beta secretion	6.552763e-5
GO:0071338	positive regulation of hair follicle cell proliferation	6.553257e-5
GO:0006678	glucosylceramide metabolic process	6.626144e-5
GO:0046620	regulation of organ growth	6.774504e-5
GO:0060271	cilium morphogenesis	6.940363e-5
GO:0046324	regulation of glucose import	6.940363e-5
GO:0071345	cellular response to cytokine stimulus	7.021552e-5
GO:0002700	regulation of production of molecular mediator of immune response	7.052273e-5
GO:0051346	negative regulation of hydrolase activity	7.069894e-5
GO:0019439	aromatic compound catabolic process	7.084865e-5
GO:0010646	regulation of cell communication	7.267718e-5
GO:0032642	regulation of chemokine production	7.301745e-5
GO:0003006	developmental process involved in reproduction	7.465315e-5
GO:0033598	mammary gland epithelial cell proliferation	7.543705e-5
GO:0051592	response to calcium ion	7.569042e-5
GO:0072278	metanephric comma-shaped body morphogenesis	7.627529e-5
GO:0043200	response to amino acid stimulus	7.739430e-5
GO:0002548	monocyte chemotaxis	7.996211e-5
GO:0072221	metanephric distal convoluted tubule development	8.209675e-5
GO:0040011	locomotion	8.295778e-5
GO:0010039	response to iron ion	8.346247e-5
GO:0050706	regulation of interleukin-1 beta secretion	8.401147e-5
GO:0006775	fat-soluble vitamin metabolic process	8.464078e-5
GO:0045786	negative regulation of cell cycle	8.479238e-5
GO:0046326	positive regulation of glucose import	8.640704e-5
GO:0048285	organelle fission	8.730215e-5
GO:0090276	regulation of peptide hormone secretion	8.810132e-5
GO:0010288	response to lead ion	8.874481e-5
GO:0001658	branching involved in ureteric bud morphogenesis	8.953283e-5
GO:0044085	cellular component biogenesis	9.116763e-5
GO:0051651	maintenance of location in cell	9.275201e-5
GO:0009750	response to fructose stimulus	9.342387e-5
GO:0010038	response to metal ion	9.412989e-5
GO:0051971	positive regulation of transmission of nerve impulse	9.418172e-5
GO:0051336	regulation of hydrolase activity	9.418594e-5
GO:0003323	type B pancreatic cell development	9.511444e-5
GO:0055080	cation homeostasis	9.513175e-5
GO:2000173	negative regulation of branching morphogenesis of a nerve	9.529104e-5
GO:0031647	regulation of protein stability	9.824340e-5
GO:0051224	negative regulation of protein transport	9.851708e-5
GO:0048731	system development	9.864455e-5
GO:0007204	elevation of cytosolic calcium ion concentration	9.910316e-5
GO:0003014	renal system process	9.949196e-5
GO:0045185	maintenance of protein location	1.009544e-4
GO:0048522	positive regulation of cellular process	1.017185e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.025620e-4
GO:0007623	circadian rhythm	1.027361e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	1.030289e-4
GO:0046639	negative regulation of alpha-beta T cell differentiation	1.035939e-4
GO:0071310	cellular response to organic substance	1.042864e-4
GO:0042990	regulation of transcription factor import into nucleus	1.047138e-4
GO:0032722	positive regulation of chemokine production	1.049692e-4
GO:0010722	regulation of ferrochelatase activity	1.055594e-4
GO:0051235	maintenance of location	1.066317e-4
GO:0043374	CD8-positive, alpha-beta T cell differentiation	1.084099e-4
GO:0032715	negative regulation of interleukin-6 production	1.086744e-4
GO:0006725	cellular aromatic compound metabolic process	1.089016e-4
GO:0015801	aromatic amino acid transport	1.096747e-4
GO:0030098	lymphocyte differentiation	1.106529e-4
GO:0002839	positive regulation of immune response to tumor cell	1.108891e-4
GO:0042572	retinol metabolic process	1.130691e-4
GO:0014866	skeletal myofibril assembly	1.138327e-4
GO:0030728	ovulation	1.146535e-4
GO:0006892	post-Golgi vesicle-mediated transport	1.159543e-4
GO:0034122	negative regulation of toll-like receptor signaling pathway	1.181048e-4
GO:0032507	maintenance of protein location in cell	1.198911e-4
GO:0051726	regulation of cell cycle	1.204086e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.227601e-4
GO:0001776	leukocyte homeostasis	1.235762e-4
GO:0030203	glycosaminoglycan metabolic process	1.235955e-4
GO:0072087	renal vesicle development	1.236651e-4
GO:0002260	lymphocyte homeostasis	1.248282e-4
GO:0002729	positive regulation of natural killer cell cytokine production	1.296982e-4
GO:2000147	positive regulation of cell motility	1.325227e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.343069e-4
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	1.363191e-4
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	1.388626e-4
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.419021e-4
GO:0072283	metanephric renal vesicle morphogenesis	1.434734e-4
GO:0030538	embryonic genitalia morphogenesis	1.450139e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.474598e-4
GO:0030003	cellular cation homeostasis	1.474945e-4
GO:0044265	cellular macromolecule catabolic process	1.476182e-4
GO:0002282	microglial cell activation involved in immune response	1.477511e-4
GO:0042110	T cell activation	1.500613e-4
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.506708e-4
GO:0002827	positive regulation of T-helper 1 type immune response	1.511027e-4
GO:0001657	ureteric bud development	1.514069e-4
GO:0032652	regulation of interleukin-1 production	1.515061e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0055114	oxidation-reduction process	1.822295e-11
GO:0042180	cellular ketone metabolic process	2.325840e-11
GO:0019752	carboxylic acid metabolic process	2.360056e-11
GO:0006082	organic acid metabolic process	7.628522e-11
GO:0022414	reproductive process	2.332809e-10
GO:0000003	reproduction	3.568517e-10
GO:0044283	small molecule biosynthetic process	3.693631e-10
GO:0050860	negative regulation of T cell receptor signaling pathway	5.784780e-10
GO:0046395	carboxylic acid catabolic process	1.349689e-8
GO:0032787	monocarboxylic acid metabolic process	1.720737e-8
GO:0048378	regulation of lateral mesodermal cell fate specification	1.913882e-8
GO:0051704	multi-organism process	2.027135e-8
GO:0046394	carboxylic acid biosynthetic process	2.072374e-8
GO:0050854	regulation of antigen receptor-mediated signaling pathway	2.787175e-8
GO:0008206	bile acid metabolic process	2.917875e-8
GO:0050777	negative regulation of immune response	3.055230e-8
GO:0006629	lipid metabolic process	4.154609e-8
GO:0090329	regulation of DNA-dependent DNA replication	4.577601e-8
GO:0051013	microtubule severing	6.045849e-8
GO:0042127	regulation of cell proliferation	6.586080e-8
GO:0010033	response to organic substance	9.350758e-8
GO:0042398	cellular modified amino acid biosynthetic process	1.010327e-7
GO:0050856	regulation of T cell receptor signaling pathway	1.368229e-7
GO:0019285	glycine betaine biosynthetic process from choline	1.393415e-7
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.639708e-7
GO:0002376	immune system process	1.723254e-7
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.962529e-7
GO:0051707	response to other organism	2.246061e-7
GO:0045671	negative regulation of osteoclast differentiation	2.497001e-7
GO:0044255	cellular lipid metabolic process	2.620347e-7
GO:0001953	negative regulation of cell-matrix adhesion	2.758925e-7
GO:0002684	positive regulation of immune system process	3.142103e-7
GO:0046381	CMP-N-acetylneuraminate metabolic process	4.205179e-7
GO:0034214	protein hexamerization	4.207148e-7
GO:0009750	response to fructose stimulus	5.375000e-7
GO:0030183	B cell differentiation	5.472159e-7
GO:0001542	ovulation from ovarian follicle	5.658471e-7
GO:0072329	monocarboxylic acid catabolic process	6.196139e-7
GO:0045226	extracellular polysaccharide biosynthetic process	7.068686e-7
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	7.185604e-7
GO:0045070	positive regulation of viral genome replication	7.453024e-7
GO:0006952	defense response	7.485694e-7
GO:0001775	cell activation	8.903193e-7
GO:0042221	response to chemical stimulus	1.011469e-6
GO:0002707	negative regulation of lymphocyte mediated immunity	1.012528e-6
GO:0051546	keratinocyte migration	1.373867e-6
GO:0006575	cellular modified amino acid metabolic process	1.405731e-6
GO:0006955	immune response	1.477683e-6
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.584990e-6
GO:0019731	antibacterial humoral response	1.629028e-6
GO:0009607	response to biotic stimulus	1.827291e-6
GO:0042448	progesterone metabolic process	2.020154e-6
GO:0008617	guanosine metabolic process	2.175103e-6
GO:0030098	lymphocyte differentiation	2.208181e-6
GO:2000104	negative regulation of DNA-dependent DNA replication	2.213168e-6
GO:0010966	regulation of phosphate transport	2.240508e-6
GO:0008652	cellular amino acid biosynthetic process	2.403416e-6
GO:0035644	phosphoanandamide dephosphorylation	2.562336e-6
GO:0018931	naphthalene metabolic process	2.822049e-6
GO:0019442	tryptophan catabolic process to acetyl-CoA	2.822049e-6
GO:0009408	response to heat	2.865451e-6
GO:0002683	negative regulation of immune system process	2.992598e-6
GO:0003417	growth plate cartilage development	3.222686e-6
GO:0050878	regulation of body fluid levels	3.636901e-6
GO:0006054	N-acetylneuraminate metabolic process	3.661441e-6
GO:0046128	purine ribonucleoside metabolic process	3.782829e-6
GO:0046649	lymphocyte activation	4.112730e-6
GO:0044281	small molecule metabolic process	4.390956e-6
GO:0007166	cell surface receptor linked signaling pathway	4.582178e-6
GO:0002521	leukocyte differentiation	4.590505e-6
GO:0022900	electron transport chain	4.734962e-6
GO:0044282	small molecule catabolic process	5.252797e-6
GO:0042278	purine nucleoside metabolic process	6.095731e-6
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	6.213860e-6
GO:0043270	positive regulation of ion transport	6.744905e-6
GO:0046500	S-adenosylmethionine metabolic process	7.004478e-6
GO:0046689	response to mercury ion	7.007213e-6
GO:0045321	leukocyte activation	7.224174e-6
GO:0010812	negative regulation of cell-substrate adhesion	7.478602e-6
GO:0007253	cytoplasmic sequestering of NF-kappaB	7.715765e-6
GO:0050896	response to stimulus	9.459571e-6
GO:0046545	development of primary female sexual characteristics	1.060135e-5
GO:0032423	regulation of mismatch repair	1.204437e-5
GO:0006749	glutathione metabolic process	1.256741e-5
GO:0002762	negative regulation of myeloid leukocyte differentiation	1.256741e-5
GO:0055014	atrial cardiac muscle cell development	1.372617e-5
GO:0010459	negative regulation of heart rate	1.377185e-5
GO:0030728	ovulation	1.446302e-5
GO:0061181	regulation of chondrocyte development	1.498883e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.558068e-5
GO:0006790	sulfur compound metabolic process	1.591287e-5
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.687006e-5
GO:0019836	hemolysis by symbiont of host erythrocytes	1.701009e-5
GO:0034644	cellular response to UV	1.730215e-5
GO:0002483	antigen processing and presentation of endogenous peptide antigen	1.841098e-5
GO:0031342	negative regulation of cell killing	1.903668e-5
GO:0050865	regulation of cell activation	2.262735e-5
GO:0000038	very long-chain fatty acid metabolic process	2.384026e-5
GO:0014743	regulation of muscle hypertrophy	2.405553e-5
GO:0007621	negative regulation of female receptivity	2.413911e-5
GO:0006116	NADH oxidation	2.413911e-5
GO:0007165	signal transduction	2.507119e-5
GO:0032876	negative regulation of DNA endoreduplication	2.565653e-5
GO:0046660	female sex differentiation	2.915721e-5
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	2.990829e-5
GO:0002694	regulation of leukocyte activation	3.004401e-5
GO:0007007	inner mitochondrial membrane organization	3.055765e-5
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	3.110747e-5
GO:0070189	kynurenine metabolic process	3.160881e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	3.166685e-5
GO:0006556	S-adenosylmethionine biosynthetic process	3.304383e-5
GO:0006091	generation of precursor metabolites and energy	3.378740e-5
GO:0042113	B cell activation	3.398231e-5
GO:0008585	female gonad development	3.556675e-5
GO:0051179	localization	3.601366e-5
GO:0008202	steroid metabolic process	3.612484e-5
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	3.778106e-5
GO:0006520	cellular amino acid metabolic process	3.785605e-5
GO:0016042	lipid catabolic process	3.796263e-5
GO:0051701	interaction with host	3.807335e-5
GO:0043652	engulfment of apoptotic cell	3.829854e-5
GO:0019060	intracellular transport of viral proteins in host cell	3.842502e-5
GO:0046967	cytosol to ER transport	3.842502e-5
GO:0007618	mating	3.942415e-5
GO:0042347	negative regulation of NF-kappaB import into nucleus	4.054241e-5
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	4.084795e-5
GO:0019882	antigen processing and presentation	4.117067e-5
GO:0002238	response to molecule of fungal origin	4.331688e-5
GO:0042364	water-soluble vitamin biosynthetic process	4.442900e-5
GO:0009617	response to bacterium	4.543914e-5
GO:0042270	protection from natural killer cell mediated cytotoxicity	4.737922e-5
GO:0010611	regulation of cardiac muscle hypertrophy	4.896889e-5
GO:0070541	response to platinum ion	5.105314e-5
GO:0006950	response to stress	5.251636e-5
GO:0046129	purine ribonucleoside biosynthetic process	5.417444e-5
GO:0007608	sensory perception of smell	5.645433e-5
GO:0022415	viral reproductive process	5.771039e-5
GO:0042473	outer ear morphogenesis	6.287345e-5
GO:0007006	mitochondrial membrane organization	6.353712e-5
GO:0043502	regulation of muscle adaptation	6.526644e-5
GO:0043069	negative regulation of programmed cell death	6.660858e-5
GO:0006508	proteolysis	6.708740e-5
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	7.101217e-5
GO:0031667	response to nutrient levels	7.318107e-5
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	7.370284e-5
GO:0050680	negative regulation of epithelial cell proliferation	7.457787e-5
GO:0005996	monosaccharide metabolic process	7.494782e-5
GO:0044242	cellular lipid catabolic process	7.918011e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	7.918033e-5
GO:0016032	viral reproduction	7.935796e-5
GO:0015805	S-adenosylmethionine transport	7.970681e-5
GO:0019541	propionate metabolic process	8.026795e-5
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	8.210170e-5
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	8.557997e-5
GO:0071394	cellular response to testosterone stimulus	8.906373e-5
GO:2000353	positive regulation of endothelial cell apoptosis	9.043642e-5
GO:0019730	antimicrobial humoral response	9.070316e-5
GO:0051716	cellular response to stimulus	9.088518e-5
GO:0043616	keratinocyte proliferation	9.428520e-5
GO:0051651	maintenance of location in cell	9.573135e-5
GO:0043066	negative regulation of apoptosis	1.007040e-4
GO:0050852	T cell receptor signaling pathway	1.047066e-4
GO:0032655	regulation of interleukin-12 production	1.053072e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	1.053792e-4
GO:0006665	sphingolipid metabolic process	1.075211e-4
GO:0050873	brown fat cell differentiation	1.126988e-4
GO:0016998	cell wall macromolecule catabolic process	1.165264e-4
GO:0010817	regulation of hormone levels	1.179735e-4
GO:0009062	fatty acid catabolic process	1.186764e-4
GO:0003416	endochondral bone growth	1.196167e-4
GO:0060548	negative regulation of cell death	1.222242e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.276044e-4
GO:0051023	regulation of immunoglobulin secretion	1.284799e-4
GO:0006578	betaine biosynthetic process	1.332724e-4
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.368127e-4
GO:0009620	response to fungus	1.382735e-4
GO:0048609	multicellular organismal reproductive process	1.388707e-4
GO:0009071	serine family amino acid catabolic process	1.398958e-4
GO:0002820	negative regulation of adaptive immune response	1.404854e-4
GO:0045910	negative regulation of DNA recombination	1.415986e-4
GO:0050867	positive regulation of cell activation	1.453750e-4
GO:0045668	negative regulation of osteoblast differentiation	1.490434e-4
GO:0007154	cell communication	1.539149e-4
GO:0045919	positive regulation of cytolysis	1.548335e-4
GO:0032695	negative regulation of interleukin-12 production	1.579203e-4
GO:0014741	negative regulation of muscle hypertrophy	1.602239e-4
GO:0008610	lipid biosynthetic process	1.628061e-4
GO:0050708	regulation of protein secretion	1.644344e-4
GO:0051053	negative regulation of DNA metabolic process	1.659388e-4
GO:0002682	regulation of immune system process	1.759454e-4
GO:0035036	sperm-egg recognition	1.761280e-4
GO:0006212	uracil catabolic process	1.809214e-4
GO:0042753	positive regulation of circadian rhythm	1.821436e-4
GO:0019098	reproductive behavior	1.883275e-4
GO:0023052	signaling	1.895662e-4
GO:0031960	response to corticosteroid stimulus	1.957727e-4
GO:0010941	regulation of cell death	1.969779e-4
GO:0051531	NFAT protein import into nucleus	1.978201e-4
GO:0048305	immunoglobulin secretion	1.980290e-4
GO:0010751	negative regulation of nitric oxide mediated signal transduction	1.986843e-4
GO:0010754	negative regulation of cGMP-mediated signaling	1.986843e-4
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	1.986843e-4
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	1.986843e-4
GO:0007109	cytokinesis, completion of separation	1.986843e-4
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.986843e-4
GO:0051234	establishment of localization	2.064356e-4
GO:0031341	regulation of cell killing	2.184179e-4
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	2.257379e-4
GO:0051260	protein homooligomerization	2.306590e-4
GO:0031348	negative regulation of defense response	2.332519e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	2.389683e-4
GO:0051384	response to glucocorticoid stimulus	2.418537e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.433781e-4
GO:0019228	regulation of action potential in neuron	2.470677e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.481494e-4
GO:0042594	response to starvation	2.484422e-4
GO:0002666	positive regulation of T cell tolerance induction	2.485251e-4
GO:0032074	negative regulation of nuclease activity	2.530024e-4
GO:0072539	T-helper 17 cell differentiation	2.551738e-4
GO:0006083	acetate metabolic process	2.551738e-4
GO:0002253	activation of immune response	2.622386e-4
GO:0009914	hormone transport	2.628197e-4
GO:0050778	positive regulation of immune response	2.645679e-4
GO:0045824	negative regulation of innate immune response	2.714088e-4
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	2.718224e-4
GO:0034097	response to cytokine stimulus	2.788502e-4
GO:0006518	peptide metabolic process	2.847798e-4
GO:0051928	positive regulation of calcium ion transport	2.864940e-4
GO:0002252	immune effector process	2.897787e-4
GO:0050907	detection of chemical stimulus involved in sensory perception	2.915163e-4
GO:0043268	positive regulation of potassium ion transport	2.937550e-4
GO:0009225	nucleotide-sugar metabolic process	3.053223e-4
GO:0002696	positive regulation of leukocyte activation	3.139448e-4
GO:0009110	vitamin biosynthetic process	3.152970e-4
GO:0006643	membrane lipid metabolic process	3.180797e-4
GO:0021847	ventricular zone neuroblast division	3.195694e-4
GO:0019543	propionate catabolic process	3.198037e-4
GO:0071482	cellular response to light stimulus	3.322972e-4
GO:0007617	mating behavior	3.413141e-4
GO:0000238	zygotene	3.462861e-4
GO:0008616	queuosine biosynthetic process	3.462861e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	3.463520e-4
GO:0007548	sex differentiation	3.507518e-4
GO:0016445	somatic diversification of immunoglobulins	3.533159e-4
GO:0050678	regulation of epithelial cell proliferation	3.553520e-4
GO:0010614	negative regulation of cardiac muscle hypertrophy	3.634285e-4
GO:0045345	positive regulation of MHC class I biosynthetic process	3.728929e-4
GO:0035881	amacrine cell differentiation	3.728929e-4
GO:0045190	isotype switching	3.815936e-4
GO:0007622	rhythmic behavior	3.853018e-4
GO:0007584	response to nutrient	3.862030e-4
GO:0048584	positive regulation of response to stimulus	4.017968e-4
GO:0031645	negative regulation of neurological system process	4.049704e-4
GO:0019853	L-ascorbic acid biosynthetic process	4.083429e-4
GO:0045577	regulation of B cell differentiation	4.288864e-4
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	4.364090e-4
GO:0032355	response to estradiol stimulus	4.402470e-4
GO:0010749	regulation of nitric oxide mediated signal transduction	4.463308e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	4.502967e-4
GO:0051249	regulation of lymphocyte activation	4.508100e-4
GO:0001906	cell killing	4.524371e-4
GO:0050727	regulation of inflammatory response	4.574474e-4
GO:0043420	anthranilate metabolic process	4.578728e-4
GO:0034516	response to vitamin B6	4.578728e-4
GO:0050863	regulation of T cell activation	4.632949e-4
GO:0043266	regulation of potassium ion transport	4.657811e-4
GO:0050805	negative regulation of synaptic transmission	4.675401e-4
GO:0006810	transport	4.736708e-4
GO:0043060	meiotic metaphase I plate congression	4.766539e-4
GO:0046903	secretion	4.797339e-4
GO:2000119	negative regulation of sodium-dependent phosphate transport	5.044923e-4
GO:0048239	negative regulation of DNA recombination at telomere	5.044923e-4
GO:0006430	lysyl-tRNA aminoacylation	5.044923e-4
GO:0007063	regulation of sister chromatid cohesion	5.072839e-4
GO:0048002	antigen processing and presentation of peptide antigen	5.191109e-4
GO:0051970	negative regulation of transmission of nerve impulse	5.345693e-4
GO:0051883	killing of cells in other organism involved in symbiotic interaction	5.414980e-4
GO:2000271	positive regulation of fibroblast apoptosis	5.418285e-4
GO:2000270	negative regulation of fibroblast apoptosis	5.418285e-4
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	5.418285e-4
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	5.418285e-4
GO:0030522	intracellular receptor mediated signaling pathway	5.454663e-4
GO:0022610	biological adhesion	5.512237e-4
GO:0071872	cellular response to epinephrine stimulus	5.579781e-4
GO:0042891	antibiotic transport	5.579781e-4
GO:0051025	negative regulation of immunoglobulin secretion	5.698877e-4
GO:0071228	cellular response to tumor cell	5.698877e-4
GO:0009116	nucleoside metabolic process	5.728564e-4
GO:0010269	response to selenium ion	5.893237e-4
GO:0071379	cellular response to prostaglandin stimulus	5.894427e-4
GO:0034374	low-density lipoprotein particle remodeling	6.057113e-4
GO:0002034	regulation of blood vessel size by renin-angiotensin	6.160050e-4
GO:0015893	drug transport	6.234901e-4
GO:0042661	regulation of mesodermal cell fate specification	6.247233e-4
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	6.255091e-4
GO:0015939	pantothenate metabolic process	6.283120e-4
GO:0002698	negative regulation of immune effector process	6.447648e-4
GO:0031640	killing of cells of other organism	6.512941e-4
GO:0002377	immunoglobulin production	6.584786e-4
GO:0006732	coenzyme metabolic process	6.685419e-4
GO:0005513	detection of calcium ion	6.748246e-4
GO:0046640	regulation of alpha-beta T cell proliferation	6.975283e-4
GO:0034104	negative regulation of tissue remodeling	6.989834e-4
GO:0050655	dermatan sulfate proteoglycan metabolic process	7.102276e-4
GO:0048512	circadian behavior	7.129302e-4
GO:0032507	maintenance of protein location in cell	7.138118e-4
GO:0071214	cellular response to abiotic stimulus	7.224035e-4
GO:0007263	nitric oxide mediated signal transduction	7.329079e-4
GO:0045137	development of primary sexual characteristics	7.341365e-4
GO:0001937	negative regulation of endothelial cell proliferation	7.465546e-4
GO:0030003	cellular cation homeostasis	7.536133e-4
GO:0071396	cellular response to lipid	7.681161e-4
GO:0042938	dipeptide transport	7.804708e-4
GO:0008615	pyridoxine biosynthetic process	7.804708e-4
GO:0034341	response to interferon-gamma	7.808651e-4
GO:0044060	regulation of endocrine process	7.882489e-4
GO:0006094	gluconeogenesis	7.900587e-4
GO:0050709	negative regulation of protein secretion	7.925669e-4
GO:0010942	positive regulation of cell death	7.966481e-4
GO:0006040	amino sugar metabolic process	8.130666e-4
GO:0009069	serine family amino acid metabolic process	8.219871e-4
GO:0030828	positive regulation of cGMP biosynthetic process	8.298479e-4
GO:0022010	central nervous system myelination	8.324040e-4
GO:0001889	liver development	8.344646e-4
GO:0006210	thymine catabolic process	8.398971e-4
GO:0050880	regulation of blood vessel size	8.668542e-4
GO:0006546	glycine catabolic process	8.794283e-4
GO:0060279	positive regulation of ovulation	8.794283e-4
GO:0021869	forebrain ventricular zone progenitor cell division	8.936898e-4
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	9.033333e-4
GO:0002312	B cell activation involved in immune response	9.270905e-4
GO:0035150	regulation of tube size	9.334222e-4
GO:0006911	phagocytosis, engulfment	9.485038e-4
GO:0050830	defense response to Gram-positive bacterium	9.612383e-4
GO:0008207	C21-steroid hormone metabolic process	9.614826e-4
GO:0045116	protein neddylation	9.645581e-4
GO:0045087	innate immune response	9.911811e-4
GO:0006707	cholesterol catabolic process	9.980028e-4
GO:0006873	cellular ion homeostasis	1.011759e-3
GO:0008406	gonad development	1.035490e-3
GO:0016525	negative regulation of angiogenesis	1.038403e-3
GO:0007566	embryo implantation	1.056052e-3
GO:0071380	cellular response to prostaglandin E stimulus	1.057410e-3
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.057410e-3
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	1.057738e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	1.064586e-3
GO:0006066	alcohol metabolic process	1.072883e-3
GO:0042759	long-chain fatty acid biosynthetic process	1.094110e-3
GO:0071496	cellular response to external stimulus	1.097533e-3
GO:0033865	nucleoside bisphosphate metabolic process	1.103795e-3
GO:0006706	steroid catabolic process	1.103795e-3
GO:0070682	proteasome regulatory particle assembly	1.108701e-3
GO:0019805	quinolinate biosynthetic process	1.108701e-3
GO:0019852	L-ascorbic acid metabolic process	1.114517e-3
GO:0016188	synaptic vesicle maturation	1.137935e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	1.137935e-3
GO:0042981	regulation of apoptosis	1.153468e-3
GO:0043067	regulation of programmed cell death	1.167734e-3
GO:0043648	dicarboxylic acid metabolic process	1.205107e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.210299e-3
GO:0010955	negative regulation of protein processing	1.219513e-3
GO:0002443	leukocyte mediated immunity	1.224182e-3
GO:0009108	coenzyme biosynthetic process	1.226628e-3
GO:0051782	negative regulation of cell division	1.266404e-3
GO:0060452	positive regulation of cardiac muscle contraction	1.266404e-3
GO:0009309	amine biosynthetic process	1.267428e-3
GO:0044106	cellular amine metabolic process	1.277029e-3
GO:0019884	antigen processing and presentation of exogenous antigen	1.304294e-3
GO:0006916	anti-apoptosis	1.304393e-3
GO:0010757	negative regulation of plasminogen activation	1.304506e-3
GO:0007034	vacuolar transport	1.311407e-3
GO:0006631	fatty acid metabolic process	1.311586e-3
GO:0048608	reproductive structure development	1.323079e-3
GO:0060766	negative regulation of androgen receptor signaling pathway	1.325111e-3
GO:0048545	response to steroid hormone stimulus	1.331412e-3
GO:0060180	female mating behavior	1.358456e-3
GO:0002669	positive regulation of T cell anergy	1.358456e-3
GO:0019695	choline metabolic process	1.363455e-3
GO:0006954	inflammatory response	1.385517e-3
GO:0001952	regulation of cell-matrix adhesion	1.386108e-3
GO:0044262	cellular carbohydrate metabolic process	1.389013e-3
GO:0008286	insulin receptor signaling pathway	1.389942e-3
GO:0046327	glycerol biosynthetic process from pyruvate	1.407272e-3
GO:0060427	lung connective tissue development	1.407272e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.407272e-3
GO:0030162	regulation of proteolysis	1.413606e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	1.428881e-3
GO:0032354	response to follicle-stimulating hormone stimulus	1.432318e-3
GO:0045185	maintenance of protein location	1.456357e-3
GO:0006672	ceramide metabolic process	1.476336e-3
GO:0002449	lymphocyte mediated immunity	1.501905e-3
GO:0031343	positive regulation of cell killing	1.514241e-3
GO:0007155	cell adhesion	1.531390e-3
GO:0002551	mast cell chemotaxis	1.538348e-3
GO:0034605	cellular response to heat	1.542517e-3
GO:0046851	negative regulation of bone remodeling	1.552305e-3
GO:0031338	regulation of vesicle fusion	1.552305e-3
GO:0014070	response to organic cyclic compound	1.560442e-3
GO:0071877	regulation of adrenergic receptor signaling pathway	1.571673e-3
GO:0006214	thymidine catabolic process	1.571673e-3
GO:0070201	regulation of establishment of protein localization	1.578854e-3
GO:0046902	regulation of mitochondrial membrane permeability	1.594374e-3
GO:0042311	vasodilation	1.628709e-3
GO:0003018	vascular process in circulatory system	1.636455e-3
GO:0050776	regulation of immune response	1.639454e-3
GO:0046879	hormone secretion	1.677599e-3
GO:0001959	regulation of cytokine-mediated signaling pathway	1.685333e-3
GO:0051235	maintenance of location	1.703097e-3
GO:0006878	cellular copper ion homeostasis	1.720865e-3
GO:0032944	regulation of mononuclear cell proliferation	1.732089e-3
GO:0007008	outer mitochondrial membrane organization	1.733545e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	1.734595e-3
GO:0006684	sphingomyelin metabolic process	1.790921e-3
GO:0019953	sexual reproduction	1.791212e-3
GO:0007589	body fluid secretion	1.797218e-3
GO:0010466	negative regulation of peptidase activity	1.826668e-3
GO:0019441	tryptophan catabolic process to kynurenine	1.839370e-3
GO:0009308	amine metabolic process	1.850568e-3
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.859300e-3
GO:0031347	regulation of defense response	1.868612e-3
GO:0061008	hepaticobiliary system development	1.870174e-3
GO:0060525	prostate glandular acinus development	1.881250e-3
GO:0006114	glycerol biosynthetic process	1.911241e-3
GO:0006145	purine base catabolic process	1.911241e-3
GO:0032980	keratinocyte activation	1.913057e-3
GO:0017144	drug metabolic process	1.955085e-3
GO:0071805	potassium ion transmembrane transport	1.970700e-3
GO:0009119	ribonucleoside metabolic process	1.979806e-3
GO:0015697	quaternary ammonium group transport	1.998215e-3
GO:0006000	fructose metabolic process	2.002986e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	2.009293e-3
GO:0050670	regulation of lymphocyte proliferation	2.024227e-3
GO:0048790	maintenance of presynaptic active zone structure	2.043664e-3
GO:0055108	Golgi to transport vesicle transport	2.043664e-3
GO:0001552	ovarian follicle atresia	2.043664e-3
GO:0008285	negative regulation of cell proliferation	2.049082e-3
GO:0002757	immune response-activating signal transduction	2.069486e-3
GO:0009266	response to temperature stimulus	2.110994e-3
GO:0009063	cellular amino acid catabolic process	2.112042e-3
GO:0042245	RNA repair	2.135130e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	2.135130e-3
GO:0002352	B cell negative selection	2.135130e-3
GO:0031117	positive regulation of microtubule depolymerization	2.136224e-3
GO:0032880	regulation of protein localization	2.150646e-3
GO:0032276	regulation of gonadotropin secretion	2.160828e-3
GO:0006568	tryptophan metabolic process	2.160828e-3
GO:0000012	single strand break repair	2.160828e-3
GO:0042035	regulation of cytokine biosynthetic process	2.163693e-3
GO:0046632	alpha-beta T cell differentiation	2.179968e-3
GO:0009267	cellular response to starvation	2.203885e-3
GO:0090361	regulation of platelet-derived growth factor production	2.224084e-3
GO:0045768	positive regulation of anti-apoptosis	2.233197e-3
GO:0046173	polyol biosynthetic process	2.236654e-3
GO:0000920	cytokinetic cell separation	2.236654e-3
GO:0015793	glycerol transport	2.256565e-3
GO:0010963	regulation of L-arginine import	2.282784e-3
GO:0051223	regulation of protein transport	2.295346e-3
GO:0001984	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure	2.303087e-3
GO:0032781	positive regulation of ATPase activity	2.327503e-3
GO:0034553	mitochondrial respiratory chain complex II assembly	2.328566e-3
GO:0030573	bile acid catabolic process	2.328566e-3
GO:0046641	positive regulation of alpha-beta T cell proliferation	2.375140e-3
GO:0009725	response to hormone stimulus	2.380404e-3
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	2.417844e-3
GO:0007599	hemostasis	2.453483e-3
GO:0006282	regulation of DNA repair	2.454582e-3
GO:0055082	cellular chemical homeostasis	2.456249e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.460540e-3
GO:0003006	developmental process involved in reproduction	2.481434e-3
GO:0021548	pons development	2.522733e-3
GO:0045767	regulation of anti-apoptosis	2.542415e-3
GO:0009056	catabolic process	2.547579e-3
GO:0051224	negative regulation of protein transport	2.556464e-3
GO:0042992	negative regulation of transcription factor import into nucleus	2.571153e-3
GO:0006635	fatty acid beta-oxidation	2.633558e-3
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	2.679327e-3
GO:0030149	sphingolipid catabolic process	2.690153e-3
GO:0010758	regulation of macrophage chemotaxis	2.690153e-3
GO:0006071	glycerol metabolic process	2.693052e-3
GO:0060759	regulation of response to cytokine stimulus	2.711084e-3
GO:0033574	response to testosterone stimulus	2.730051e-3
GO:0006720	isoprenoid metabolic process	2.730051e-3
GO:0042036	negative regulation of cytokine biosynthetic process	2.736843e-3
GO:0009991	response to extracellular stimulus	2.756264e-3
GO:0005975	carbohydrate metabolic process	2.788863e-3
GO:0051251	positive regulation of lymphocyte activation	2.793199e-3
GO:0071731	response to nitric oxide	2.807346e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	2.816418e-3
GO:0070663	regulation of leukocyte proliferation	2.877107e-3
GO:0045765	regulation of angiogenesis	2.884593e-3
GO:0000712	resolution of meiotic recombination intermediates	2.887410e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	2.895759e-3
GO:0035883	enteroendocrine cell differentiation	2.895759e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	2.895759e-3
GO:0050801	ion homeostasis	2.933555e-3
GO:0042701	progesterone secretion	2.969134e-3
GO:0071397	cellular response to cholesterol	2.981763e-3
GO:0045670	regulation of osteoclast differentiation	2.992427e-3
GO:0055070	copper ion homeostasis	3.075713e-3
GO:0051641	cellular localization	3.168129e-3