Novel motif:117

name:	motif117_SKSNGCGCTSN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	6.786705e-9
GO:0043503	skeletal muscle fiber adaptation	1.645276e-8
GO:0031442	positive regulation of mRNA 3'-end processing	5.019044e-8
GO:0006768	biotin metabolic process	8.404805e-8
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.522595e-7
GO:0035470	positive regulation of vascular wound healing	2.476867e-7
GO:0009440	cyanate catabolic process	9.379166e-7
GO:0008033	tRNA processing	1.156828e-6
GO:0015878	biotin transport	1.331868e-6
GO:0015887	pantothenate transmembrane transport	1.331868e-6
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2.021992e-6
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	2.039557e-6
GO:0051898	negative regulation of protein kinase B signaling cascade	3.161718e-6
GO:0010982	regulation of high-density lipoprotein particle clearance	3.182567e-6
GO:0060038	cardiac muscle cell proliferation	3.349383e-6
GO:0006548	histidine catabolic process	4.883903e-6
GO:0050685	positive regulation of mRNA processing	5.244131e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	5.555120e-6
GO:0032383	regulation of intracellular cholesterol transport	6.191724e-6
GO:0042136	neurotransmitter biosynthetic process	6.450758e-6
GO:0002002	regulation of angiotensin levels in blood	7.897887e-6
GO:0031468	nuclear envelope reassembly	8.089306e-6
GO:0055075	potassium ion homeostasis	9.238019e-6
GO:0006884	cell volume homeostasis	9.836570e-6
GO:0048102	autophagic cell death	9.962930e-6
GO:0006420	arginyl-tRNA aminoacylation	1.064954e-5
GO:0035461	vitamin transmembrane transport	1.233034e-5
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.320360e-5
GO:0006268	DNA unwinding involved in replication	1.578898e-5
GO:0060419	heart growth	1.891984e-5
GO:0009264	deoxyribonucleotide catabolic process	1.901196e-5
GO:0048050	post-embryonic eye morphogenesis	2.218397e-5
GO:0018352	protein-pyridoxal-5-phosphate linkage	2.292720e-5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2.469677e-5
GO:0031440	regulation of mRNA 3'-end processing	2.536818e-5
GO:0010225	response to UV-C	2.792563e-5
GO:0043089	positive regulation of Cdc42 GTPase activity	2.898100e-5
GO:0043097	pyrimidine nucleoside salvage	3.143770e-5
GO:0051586	positive regulation of dopamine uptake	3.405032e-5
GO:0070988	demethylation	4.279808e-5
GO:0051534	negative regulation of NFAT protein import into nucleus	4.283097e-5
GO:0010897	negative regulation of triglyceride catabolic process	4.587298e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	4.587298e-5
GO:0016577	histone demethylation	4.593668e-5
GO:0010107	potassium ion import	5.097993e-5
GO:0035357	peroxisome proliferator activated receptor signaling pathway	5.739409e-5
GO:0010988	regulation of low-density lipoprotein particle clearance	5.870265e-5
GO:0060177	regulation of angiotensin metabolic process	5.899061e-5
GO:0006348	chromatin silencing at telomere	6.964059e-5
GO:0002071	glandular epithelial cell maturation	6.964059e-5
GO:0060999	positive regulation of dendritic spine development	7.312186e-5
GO:0055017	cardiac muscle tissue growth	8.906034e-5
GO:0050779	RNA destabilization	9.488761e-5
GO:0000724	double-strand break repair via homologous recombination	9.542175e-5
GO:0010984	regulation of lipoprotein particle clearance	1.033063e-4
GO:2000249	regulation of actin cytoskeleton reorganization	1.045644e-4
GO:0021568	rhombomere 2 development	1.152924e-4
GO:0032006	regulation of TOR signaling cascade	1.250712e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.272170e-4
GO:0072337	modified amino acid transport	1.334305e-4
GO:0030539	male genitalia development	1.470506e-4
GO:0009304	tRNA transcription	1.522234e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	1.522904e-4
GO:0061157	mRNA destabilization	1.522904e-4
GO:0002036	regulation of L-glutamate transport	1.560221e-4
GO:0048343	paraxial mesodermal cell fate commitment	1.600097e-4
GO:0001766	membrane raft polarization	1.601699e-4
GO:0007614	short-term memory	1.863058e-4
GO:0032862	activation of Rho GTPase activity	1.896885e-4
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.913483e-4
GO:0042420	dopamine catabolic process	1.938499e-4
GO:0031848	protection from non-homologous end joining at telomere	1.951112e-4
GO:0007379	segment specification	1.995164e-4
GO:0000725	recombinational repair	2.115556e-4
GO:0003326	pancreatic A cell fate commitment	2.161794e-4
GO:0003329	pancreatic PP cell fate commitment	2.161794e-4
GO:0001881	receptor recycling	2.170176e-4
GO:0070198	protein localization to chromosome, telomeric region	2.178836e-4
GO:0000731	DNA synthesis involved in DNA repair	2.205871e-4
GO:0071071	regulation of phospholipid biosynthetic process	2.226533e-4
GO:0022601	menstrual cycle phase	2.271488e-4
GO:0051764	actin crosslink formation	2.299341e-4
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.340984e-4
GO:0040015	negative regulation of multicellular organism growth	2.403575e-4
GO:0006482	protein demethylation	2.466053e-4
GO:0006540	glutamate decarboxylation to succinate	2.486651e-4
GO:0042424	catecholamine catabolic process	2.559010e-4
GO:2000786	positive regulation of autophagic vacuole assembly	2.596827e-4
GO:0071585	detoxification of cadmium ion	2.596827e-4
GO:0006778	porphyrin-containing compound metabolic process	2.834153e-4
GO:0072070	loop of Henle development	2.871402e-4
GO:0008272	sulfate transport	3.205815e-4
GO:0009451	RNA modification	3.243246e-4
GO:0034766	negative regulation of ion transmembrane transport	3.305143e-4
GO:0034723	DNA replication-dependent nucleosome organization	3.374492e-4
GO:0055026	negative regulation of cardiac muscle tissue development	3.374492e-4
GO:0071072	negative regulation of phospholipid biosynthetic process	3.448750e-4
GO:0045007	depurination	3.498614e-4
GO:0035356	cellular triglyceride homeostasis	3.498614e-4
GO:0030421	defecation	3.498614e-4
GO:0060430	lung saccule development	3.852040e-4
GO:0002357	defense response to tumor cell	3.853600e-4
GO:0045922	negative regulation of fatty acid metabolic process	3.880299e-4
GO:0007051	spindle organization	4.107491e-4
GO:0031558	induction of apoptosis in response to chemical stimulus	4.110167e-4
GO:0072086	specification of loop of Henle identity	4.111608e-4
GO:0071732	cellular response to nitric oxide	4.201713e-4
GO:0001946	lymphangiogenesis	4.332659e-4
GO:0006544	glycine metabolic process	4.821120e-4
GO:0031297	replication fork processing	5.125223e-4
GO:0051013	microtubule severing	5.196934e-4
GO:0070194	synaptonemal complex disassembly	5.219883e-4
GO:0044088	regulation of vacuole organization	5.219883e-4
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	5.219883e-4
GO:0045217	cell-cell junction maintenance	5.288544e-4
GO:0007288	sperm axoneme assembly	5.331109e-4
GO:0032312	regulation of ARF GTPase activity	5.439897e-4
GO:0006449	regulation of translational termination	5.679539e-4
GO:0006261	DNA-dependent DNA replication	5.884655e-4
GO:0048752	semicircular canal morphogenesis	5.982135e-4
GO:0006400	tRNA modification	6.111108e-4
GO:0051532	regulation of NFAT protein import into nucleus	6.671738e-4
GO:0006529	asparagine biosynthetic process	7.111688e-4
GO:0051181	cofactor transport	7.138749e-4
GO:0019264	glycine biosynthetic process from serine	7.227826e-4
GO:0090002	establishment of protein localization in plasma membrane	7.441672e-4
GO:0033013	tetrapyrrole metabolic process	7.560541e-4
GO:0000093	mitotic telophase	7.606177e-4
GO:0048561	establishment of organ orientation	7.678643e-4
GO:0015886	heme transport	7.750291e-4
GO:0045794	negative regulation of cell volume	7.910164e-4
GO:0006285	base-excision repair, AP site formation	7.972776e-4
GO:0042069	regulation of catecholamine metabolic process	8.950183e-4
GO:0032007	negative regulation of TOR signaling cascade	8.969008e-4
GO:0043088	regulation of Cdc42 GTPase activity	9.016631e-4
GO:0031936	negative regulation of chromatin silencing	9.025188e-4
GO:0031507	heterochromatin formation	9.296857e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	9.403938e-4
GO:0046134	pyrimidine nucleoside biosynthetic process	9.824927e-4
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	1.039055e-3
GO:0048627	myoblast development	1.086475e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.102818e-3
GO:0043973	histone H3-K4 acetylation	1.102818e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.102818e-3
GO:0006478	peptidyl-tyrosine sulfation	1.102818e-3
GO:0042417	dopamine metabolic process	1.112787e-3
GO:0032864	activation of Cdc42 GTPase activity	1.149051e-3
GO:0090398	cellular senescence	1.165228e-3
GO:0018993	somatic sex determination	1.191081e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	1.196699e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.197706e-3
GO:0090307	spindle assembly involved in mitosis	1.212448e-3
GO:0007182	common-partner SMAD protein phosphorylation	1.215182e-3
GO:0000413	protein peptidyl-prolyl isomerization	1.215538e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	1.223476e-3
GO:0014888	striated muscle adaptation	1.238872e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.394915e-3
GO:0010735	positive regulation of transcription via serum response element binding	1.400065e-3
GO:0033002	muscle cell proliferation	1.451244e-3
GO:0010835	regulation of protein ADP-ribosylation	1.468991e-3
GO:0046684	response to pyrethroid	1.488747e-3
GO:0090281	negative regulation of calcium ion import	1.515238e-3
GO:0071584	negative regulation of zinc ion import	1.515238e-3
GO:0031627	telomeric loop formation	1.515238e-3
GO:0051324	prophase	1.626483e-3
GO:0090303	positive regulation of wound healing	1.691402e-3
GO:0060969	negative regulation of gene silencing	1.716744e-3
GO:0043174	nucleoside salvage	1.760325e-3
GO:0002523	leukocyte migration involved in inflammatory response	1.765604e-3
GO:0031118	rRNA pseudouridine synthesis	1.812085e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.812085e-3
GO:0009155	purine deoxyribonucleotide catabolic process	1.856342e-3
GO:0032615	interleukin-12 production	1.859958e-3
GO:0031055	chromatin remodeling at centromere	1.874556e-3
GO:0070368	positive regulation of hepatocyte differentiation	1.894111e-3
GO:0046015	regulation of transcription by glucose	1.898767e-3
GO:0003360	brainstem development	1.915377e-3
GO:0045112	integrin biosynthetic process	1.952282e-3
GO:0042168	heme metabolic process	2.011926e-3
GO:0006760	folic acid-containing compound metabolic process	2.162298e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	2.167662e-3
GO:0071104	response to interleukin-9	2.233786e-3
GO:0042942	D-serine transport	2.233786e-3
GO:0002418	immune response to tumor cell	2.233786e-3
GO:0032863	activation of Rac GTPase activity	2.234669e-3
GO:0090344	negative regulation of cell aging	2.239346e-3
GO:0042133	neurotransmitter metabolic process	2.266482e-3
GO:0034776	response to histamine	2.297422e-3
GO:0071422	succinate transmembrane transport	2.297422e-3
GO:0007398	ectoderm development	2.303113e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	2.321835e-3
GO:0045660	positive regulation of neutrophil differentiation	2.340964e-3
GO:0031365	N-terminal protein amino acid modification	2.416631e-3
GO:0071956	cellular component maintenance at cellular level	2.417268e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	2.438314e-3
GO:0007386	compartment pattern specification	2.495000e-3
GO:0043542	endothelial cell migration	2.507081e-3
GO:0042053	regulation of dopamine metabolic process	2.515293e-3
GO:0006244	pyrimidine nucleotide catabolic process	2.538481e-3
GO:0006779	porphyrin-containing compound biosynthetic process	2.547579e-3
GO:0090141	positive regulation of mitochondrial fission	2.555478e-3
GO:0051590	positive regulation of neurotransmitter transport	2.559548e-3
GO:0070544	histone H3-K36 demethylation	2.577188e-3
GO:0031935	regulation of chromatin silencing	2.609095e-3
GO:0080111	DNA demethylation	2.609095e-3
GO:0031999	negative regulation of fatty acid beta-oxidation	2.649009e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.649009e-3
GO:0006391	transcription initiation from mitochondrial promoter	2.649009e-3
GO:0042538	hyperosmotic salinity response	2.672517e-3
GO:0045948	positive regulation of translational initiation	2.710542e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	2.711054e-3
GO:0051645	Golgi localization	2.752627e-3
GO:0045064	T-helper 2 cell differentiation	2.752627e-3
GO:0002315	marginal zone B cell differentiation	2.752627e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.775581e-3
GO:0033602	negative regulation of dopamine secretion	2.815452e-3
GO:0014034	neural crest cell fate commitment	2.818892e-3
GO:0070327	thyroid hormone transport	2.830661e-3
GO:0060580	ventral spinal cord interneuron fate determination	2.965297e-3
GO:0046984	regulation of hemoglobin biosynthetic process	2.965297e-3
GO:0003327	type B pancreatic cell fate commitment	2.965297e-3
GO:0030903	notochord development	3.038644e-3
GO:0000072	M phase specific microtubule process	3.068995e-3
GO:0032319	regulation of Rho GTPase activity	3.123132e-3
GO:0003310	pancreatic A cell differentiation	3.189641e-3
GO:0042732	D-xylose metabolic process	3.191912e-3
GO:0002522	leukocyte migration involved in immune response	3.191912e-3
GO:0044070	regulation of anion transport	3.220437e-3
GO:0060160	negative regulation of dopamine receptor signaling pathway	3.244398e-3
GO:0006335	DNA replication-dependent nucleosome assembly	3.244398e-3
GO:0002003	angiotensin maturation	3.244398e-3
GO:0090342	regulation of cell aging	3.271390e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	3.333643e-3
GO:0022027	interkinetic nuclear migration	3.405414e-3
GO:0070979	protein K11-linked ubiquitination	3.429502e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	3.486364e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	3.535278e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	3.556098e-3
GO:0009303	rRNA transcription	3.572062e-3
GO:0061014	positive regulation of mRNA catabolic process	3.600659e-3
GO:0006491	N-glycan processing	3.611897e-3
GO:0060017	parathyroid gland development	3.673448e-3
GO:0021871	forebrain regionalization	3.723085e-3
GO:0002921	negative regulation of humoral immune response	3.760661e-3
GO:0033604	negative regulation of catecholamine secretion	3.815003e-3
GO:0042703	menstruation	3.864760e-3
GO:0003406	retinal pigment epithelium development	3.864760e-3
GO:0019101	female somatic sex determination	3.864760e-3
GO:0021986	habenula development	3.910767e-3
GO:0045415	negative regulation of interleukin-8 biosynthetic process	3.984739e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	3.984739e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	3.984739e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	4.005633e-3
GO:0072610	interleukin-12 secretion	4.117701e-3
GO:0002408	myeloid dendritic cell chemotaxis	4.117701e-3
GO:0002074	extraocular skeletal muscle development	4.117701e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	4.230832e-3
GO:0007090	regulation of S phase of mitotic cell cycle	4.235667e-3
GO:2000465	regulation of glycogen (starch) synthase activity	4.235815e-3
GO:0070309	lens fiber cell morphogenesis	4.251944e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	4.326292e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	4.329511e-3
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	4.329511e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	4.463491e-3
GO:0071469	cellular response to alkalinity	4.465577e-3
GO:0031860	telomeric 3' overhang formation	4.465577e-3
GO:0071722	detoxification of arsenic-containing substance	4.465577e-3
GO:0019413	acetate biosynthetic process	4.465577e-3
GO:0019542	propionate biosynthetic process	4.465577e-3
GO:0031081	nuclear pore distribution	4.465577e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	4.561966e-3
GO:0042309	homoiothermy	4.708885e-3
GO:0046333	octopamine metabolic process	4.708885e-3
GO:0051225	spindle assembly	4.742760e-3
GO:0070307	lens fiber cell development	4.766897e-3
GO:0018208	peptidyl-proline modification	4.788682e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	4.998306e-3
GO:2000077	negative regulation of type B pancreatic cell development	5.156547e-3
GO:0044205	'de novo' UMP biosynthetic process	5.156547e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	5.259068e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	5.259068e-3
GO:0034470	ncRNA processing	5.272550e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	5.396800e-3
GO:0050772	positive regulation of axonogenesis	5.420742e-3
GO:0006538	glutamate catabolic process	5.533302e-3
GO:0030327	prenylated protein catabolic process	5.626692e-3
GO:0060178	regulation of exocyst localization	5.626692e-3
GO:0001928	regulation of exocyst assembly	5.626692e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	5.667824e-3
GO:0034969	histone arginine methylation	5.683938e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	5.688778e-3
GO:0006281	DNA repair	5.811310e-3
GO:0035414	negative regulation of catenin import into nucleus	5.877360e-3
GO:0051935	glutamate uptake involved in synaptic transmission	5.927361e-3
GO:0006013	mannose metabolic process	5.942210e-3
GO:0051725	protein de-ADP-ribosylation	6.097341e-3
GO:0000022	mitotic spindle elongation	6.097341e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	6.141211e-3
GO:0006419	alanyl-tRNA aminoacylation	6.294673e-3
GO:0032288	myelin assembly	6.300203e-3
GO:0016233	telomere capping	6.393833e-3
GO:0006447	regulation of translational initiation by iron	6.393833e-3
GO:0071218	cellular response to misfolded protein	6.427750e-3
GO:0042696	menarche	6.443491e-3
GO:0005997	xylulose metabolic process	6.443491e-3
GO:0002693	positive regulation of cellular extravasation	6.463929e-3
GO:0072061	inner medullary collecting duct development	6.549308e-3
GO:0097022	lymphocyte migration into lymph node	6.549308e-3
GO:0072060	outer medullary collecting duct development	6.549308e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	6.549308e-3
GO:0009798	axis specification	6.579837e-3
GO:0010816	calcitonin catabolic process	6.598159e-3
GO:0034959	endothelin maturation	6.598159e-3
GO:0010814	substance P catabolic process	6.598159e-3
GO:0071316	cellular response to nicotine	6.601396e-3
GO:0035419	activation of MAPK activity involved in innate immune response	6.617259e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	6.617259e-3
GO:0051882	mitochondrial depolarization	6.635171e-3
GO:0060286	flagellar cell motility	6.635171e-3
GO:0043622	cortical microtubule organization	6.635171e-3
GO:0030103	vasopressin secretion	6.635171e-3
GO:0045065	cytotoxic T cell differentiation	6.638861e-3
GO:0021796	cerebral cortex regionalization	6.638861e-3
GO:0016140	O-glycoside metabolic process	6.647276e-3
GO:0061205	paramesonephric duct development	6.657975e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	6.657975e-3
GO:0060242	contact inhibition	6.657975e-3
GO:0034198	cellular response to amino acid starvation	6.657975e-3
GO:0030953	astral microtubule organization	6.812665e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	6.812665e-3
GO:0032321	positive regulation of Rho GTPase activity	6.885635e-3
GO:0015816	glycine transport	6.912870e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	6.960311e-3
GO:0045994	positive regulation of translational initiation by iron	7.464846e-3
GO:0000076	DNA replication checkpoint	7.464846e-3
GO:0002037	negative regulation of L-glutamate transport	7.464846e-3
GO:0001522	pseudouridine synthesis	7.512571e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	7.519352e-3
GO:0060976	coronary vasculature development	7.555088e-3
GO:0043985	histone H4-R3 methylation	7.686661e-3
GO:0006547	histidine metabolic process	7.731451e-3
GO:0045820	negative regulation of glycolysis	7.829805e-3
GO:0007020	microtubule nucleation	7.871836e-3
GO:0072081	specification of nephron tubule identity	7.909586e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	7.938407e-3
GO:0009069	serine family amino acid metabolic process	7.949893e-3
GO:0042167	heme catabolic process	7.978662e-3
GO:0051956	negative regulation of amino acid transport	8.040203e-3
GO:0051955	regulation of amino acid transport	8.050575e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	8.463682e-3
GO:0045329	carnitine biosynthetic process	8.575819e-3
GO:0032793	positive regulation of CREB transcription factor activity	8.647368e-3
GO:0048149	behavioral response to ethanol	8.678771e-3
GO:0006189	'de novo' IMP biosynthetic process	8.828636e-3
GO:0051953	negative regulation of amine transport	8.851401e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	8.983590e-3
GO:0051220	cytoplasmic sequestering of protein	8.983590e-3
GO:0019083	viral transcription	9.011082e-3
GO:0060998	regulation of dendritic spine development	9.030347e-3
GO:0006415	translational termination	9.112340e-3
GO:0021592	fourth ventricle development	9.211556e-3
GO:0010529	negative regulation of transposition	9.211556e-3
GO:0070814	hydrogen sulfide biosynthetic process	9.295574e-3
GO:0071423	malate transmembrane transport	9.349443e-3
GO:0090324	negative regulation of oxidative phosphorylation	9.349443e-3
GO:0006844	acyl carnitine transport	9.349443e-3
GO:0015919	peroxisomal membrane transport	9.349443e-3
GO:0015709	thiosulfate transport	9.349443e-3
GO:0010255	glucose mediated signaling pathway	9.349443e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	9.493141e-3
GO:0060023	soft palate development	9.493141e-3
GO:0051584	regulation of dopamine uptake	9.534751e-3
GO:0030237	female sex determination	9.594499e-3
GO:0043501	skeletal muscle adaptation	9.624512e-3
GO:0044314	protein K27-linked ubiquitination	9.655168e-3
GO:0061099	negative regulation of protein tyrosine kinase activity	9.797394e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	9.920568e-3
GO:0021759	globus pallidus development	9.920568e-3
GO:0060061	Spemann organizer formation	9.920956e-3
GO:0090150	establishment of protein localization in membrane	1.003449e-2
GO:0060923	cardiac muscle cell fate commitment	1.005365e-2
GO:0097039	protein linear polyubiquitination	1.005365e-2
GO:0001768	establishment of T cell polarity	1.008230e-2
GO:0006707	cholesterol catabolic process	1.012709e-2
GO:0001826	inner cell mass cell differentiation	1.016108e-2
GO:0015864	pyrimidine nucleoside transport	1.016108e-2
GO:0031427	response to methotrexate	1.021992e-2
GO:0060028	convergent extension involved in axis elongation	1.021992e-2
GO:0019086	late viral mRNA transcription	1.021992e-2
GO:0018206	peptidyl-methionine modification	1.027777e-2
GO:0007140	male meiosis	1.029476e-2
GO:0032984	macromolecular complex disassembly	1.029683e-2
GO:0006646	phosphatidylethanolamine biosynthetic process	1.032248e-2
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.049359e-2
GO:0001510	RNA methylation	1.050991e-2
GO:0006998	nuclear envelope organization	1.055873e-2
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.059518e-2
GO:0097107	postsynaptic density assembly	1.059518e-2
GO:0045963	negative regulation of dopamine metabolic process	1.059518e-2
GO:0050668	positive regulation of homocysteine metabolic process	1.059518e-2
GO:0007128	meiotic prophase I	1.086151e-2
GO:0051684	maintenance of Golgi location	1.100458e-2
GO:0042664	negative regulation of endodermal cell fate specification	1.100458e-2
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	1.100458e-2
GO:0060975	cardioblast migration to the midline involved in heart field formation	1.100458e-2
GO:0060921	sinoatrial node cell differentiation	1.100458e-2
GO:0003236	sinus venosus morphogenesis	1.100458e-2
GO:0003210	cardiac atrium formation	1.100458e-2
GO:0010509	polyamine homeostasis	1.100458e-2
GO:0003241	growth involved in heart morphogenesis	1.100458e-2
GO:0006427	histidyl-tRNA aminoacylation	1.100458e-2
GO:0003259	cardioblast anterior-lateral migration	1.100458e-2
GO:0000089	mitotic metaphase	1.114306e-2
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.121726e-2
GO:0009262	deoxyribonucleotide metabolic process	1.130651e-2
GO:0006220	pyrimidine nucleotide metabolic process	1.142849e-2
GO:0030007	cellular potassium ion homeostasis	1.154991e-2
GO:0070212	protein poly-ADP-ribosylation	1.154991e-2
GO:0035510	DNA dealkylation	1.165627e-2
GO:0032933	SREBP-mediated signaling pathway	1.191529e-2
GO:0030262	apoptotic nuclear change	1.207047e-2
GO:0051255	spindle midzone assembly	1.227452e-2
GO:0045717	negative regulation of fatty acid biosynthetic process	1.237775e-2
GO:0031017	exocrine pancreas development	1.262487e-2
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.263313e-2
GO:0042711	maternal behavior	1.263313e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	1.263313e-2
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.271129e-2
GO:0001840	neural plate development	1.271129e-2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.296131e-2
GO:0042255	ribosome assembly	1.299052e-2
GO:0010890	positive regulation of sequestering of triglyceride	1.300342e-2
GO:0021569	rhombomere 3 development	1.310448e-2
GO:0010985	negative regulation of lipoprotein particle clearance	1.310448e-2
GO:0051292	nuclear pore complex assembly	1.325877e-2
GO:0042335	cuticle development	1.325877e-2
GO:0016486	peptide hormone processing	1.347268e-2
GO:0060377	negative regulation of mast cell differentiation	1.357771e-2
GO:0045403	negative regulation of interleukin-4 biosynthetic process	1.357771e-2
GO:0070512	positive regulation of histone H4-K20 methylation	1.357771e-2
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.357771e-2
GO:2000620	positive regulation of histone H4-K16 acetylation	1.357771e-2
GO:2000617	positive regulation of histone H3-K9 acetylation	1.357771e-2
GO:2000002	negative regulation of DNA damage checkpoint	1.357771e-2
GO:0003192	mitral valve formation	1.357771e-2
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.357771e-2
GO:0002295	T-helper cell lineage commitment	1.357771e-2
GO:0003195	tricuspid valve formation	1.357771e-2
GO:0014895	smooth muscle hypertrophy	1.357771e-2
GO:0021551	central nervous system morphogenesis	1.357771e-2
GO:0021588	cerebellum formation	1.357771e-2
GO:0033326	cerebrospinal fluid secretion	1.372116e-2
GO:0090129	positive regulation of synapse maturation	1.397129e-2
GO:0071731	response to nitric oxide	1.404116e-2
GO:0001757	somite specification	1.409022e-2
GO:0002380	immunoglobulin secretion involved in immune response	1.417390e-2
GO:0009235	cobalamin metabolic process	1.417390e-2
GO:0050872	white fat cell differentiation	1.423981e-2
GO:0043241	protein complex disassembly	1.430000e-2
GO:0045819	positive regulation of glycogen catabolic process	1.440582e-2
GO:0045606	positive regulation of epidermal cell differentiation	1.473351e-2
GO:0046628	positive regulation of insulin receptor signaling pathway	1.480721e-2
GO:0009972	cytidine deamination	1.482961e-2
GO:0060920	pacemaker cell differentiation	1.486160e-2
GO:0052565	response to defense-related host nitric oxide production	1.486160e-2
GO:0030844	positive regulation of intermediate filament depolymerization	1.486160e-2
GO:0003175	tricuspid valve development	1.486160e-2
GO:0071474	cellular hyperosmotic response	1.502650e-2
GO:0018105	peptidyl-serine phosphorylation	1.506245e-2
GO:0061013	regulation of mRNA catabolic process	1.508254e-2
GO:0006360	transcription from RNA polymerase I promoter	1.512486e-2
GO:0032008	positive regulation of TOR signaling cascade	1.515469e-2
GO:0032922	circadian regulation of gene expression	1.518460e-2
GO:0071470	cellular response to osmotic stress	1.523477e-2
GO:0070857	regulation of bile acid biosynthetic process	1.529988e-2
GO:0003218	cardiac left ventricle formation	1.529988e-2
GO:0070489	T cell aggregation	1.535679e-2
GO:0043461	proton-transporting ATP synthase complex assembly	1.553976e-2
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1.553976e-2
GO:0072144	glomerular mesangial cell development	1.569032e-2
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.569032e-2
GO:0072011	glomerular endothelium development	1.569032e-2
GO:0009637	response to blue light	1.573790e-2
GO:0034260	negative regulation of GTPase activity	1.585866e-2
GO:0021658	rhombomere 3 morphogenesis	1.588456e-2
GO:0051182	coenzyme transport	1.588456e-2
GO:0006546	glycine catabolic process	1.593654e-2
GO:0015862	uridine transport	1.596817e-2
GO:0003184	pulmonary valve morphogenesis	1.596817e-2
GO:0060179	male mating behavior	1.597501e-2
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.597501e-2
GO:0007063	regulation of sister chromatid cohesion	1.601338e-2
GO:0006284	base-excision repair	1.603961e-2
GO:0009394	2'-deoxyribonucleotide metabolic process	1.644682e-2
GO:0009070	serine family amino acid biosynthetic process	1.651787e-2
GO:0000712	resolution of meiotic recombination intermediates	1.657640e-2
GO:0072553	terminal button organization	1.696495e-2
GO:0034231	islet amyloid polypeptide processing	1.696495e-2
GO:0000088	mitotic prophase	1.696495e-2
GO:0034230	enkephalin processing	1.696495e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050668	positive regulation of homocysteine metabolic process	9.993106e-7
GO:0045963	negative regulation of dopamine metabolic process	9.993106e-7
GO:0055015	ventricular cardiac muscle cell development	2.535470e-6
GO:0071294	cellular response to zinc ion	3.386559e-6
GO:0043973	histone H3-K4 acetylation	4.228854e-6
GO:0046985	positive regulation of hemoglobin biosynthetic process	4.228854e-6
GO:0035269	protein O-linked mannosylation	4.228854e-6
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	4.228854e-6
GO:0006829	zinc ion transport	4.240007e-6
GO:2000020	positive regulation of male gonad development	6.673759e-6
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.584391e-5
GO:0035307	positive regulation of protein dephosphorylation	2.235522e-5
GO:0000183	chromatin silencing at rDNA	2.334561e-5
GO:0090161	Golgi ribbon formation	2.415763e-5
GO:0030035	microspike assembly	2.761058e-5
GO:0061034	olfactory bulb mitral cell layer development	2.842038e-5
GO:0035306	positive regulation of dephosphorylation	3.318695e-5
GO:0070316	regulation of G0 to G1 transition	3.399904e-5
GO:0046847	filopodium assembly	3.575974e-5
GO:2000195	negative regulation of female gonad development	5.229123e-5
GO:0021526	medial motor column neuron differentiation	5.347379e-5
GO:0071422	succinate transmembrane transport	5.347379e-5
GO:0046580	negative regulation of Ras protein signal transduction	5.422592e-5
GO:2000018	regulation of male gonad development	5.572383e-5
GO:0016925	protein sumoylation	5.623617e-5
GO:0006383	transcription from RNA polymerase III promoter	5.706498e-5
GO:0021696	cerebellar cortex morphogenesis	7.341940e-5
GO:0048672	positive regulation of collateral sprouting	8.248710e-5
GO:0021819	layer formation in cerebral cortex	8.251215e-5
GO:0021527	spinal cord association neuron differentiation	8.383226e-5
GO:0048665	neuron fate specification	9.139195e-5
GO:0070179	D-serine biosynthetic process	9.998660e-5
GO:0035674	tricarboxylic acid transmembrane transport	9.998660e-5
GO:0014028	notochord formation	9.998660e-5
GO:0046984	regulation of hemoglobin biosynthetic process	1.001283e-4
GO:0046416	D-amino acid metabolic process	1.191805e-4
GO:0051586	positive regulation of dopamine uptake	1.447431e-4
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.565917e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	1.687811e-4
GO:0021695	cerebellar cortex development	1.691995e-4
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	2.010220e-4
GO:0006011	UDP-glucose metabolic process	2.016877e-4
GO:0035520	monoubiquitinated protein deubiquitination	2.016877e-4
GO:0021511	spinal cord patterning	2.330415e-4
GO:0018205	peptidyl-lysine modification	2.407067e-4
GO:0021513	spinal cord dorsal/ventral patterning	2.430810e-4
GO:0035024	negative regulation of Rho protein signal transduction	2.437699e-4
GO:0015876	acetyl-CoA transport	2.511731e-4
GO:0006342	chromatin silencing	2.529235e-4
GO:0035444	nickel ion transmembrane transport	2.607722e-4
GO:0070278	extracellular matrix constituent secretion	2.636115e-4
GO:0010260	organ senescence	2.636115e-4
GO:0002098	tRNA wobble uridine modification	2.749667e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.970552e-4
GO:0060452	positive regulation of cardiac muscle contraction	2.970552e-4
GO:0051176	positive regulation of sulfur metabolic process	3.216518e-4
GO:0034227	tRNA thio-modification	3.817561e-4
GO:0018076	N-terminal peptidyl-lysine acetylation	3.817561e-4
GO:0032312	regulation of ARF GTPase activity	3.909787e-4
GO:2000194	regulation of female gonad development	3.930340e-4
GO:0021871	forebrain regionalization	4.107554e-4
GO:0055014	atrial cardiac muscle cell development	4.396171e-4
GO:0045647	negative regulation of erythrocyte differentiation	4.700188e-4
GO:0090083	regulation of inclusion body assembly	4.821897e-4
GO:0035855	megakaryocyte development	4.821897e-4
GO:0006474	N-terminal protein amino acid acetylation	4.924490e-4
GO:0070318	positive regulation of G0 to G1 transition	5.037032e-4
GO:0021514	ventral spinal cord interneuron differentiation	5.270274e-4
GO:0070831	basement membrane assembly	5.780599e-4
GO:0019255	glucose 1-phosphate metabolic process	5.906008e-4
GO:0019101	female somatic sex determination	6.309555e-4
GO:0072355	histone H3-T3 phosphorylation	6.309555e-4
GO:0042703	menstruation	6.309555e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	6.309555e-4
GO:0006258	UDP-glucose catabolic process	6.309555e-4
GO:0018293	protein-FAD linkage	6.309555e-4
GO:0060579	ventral spinal cord interneuron fate commitment	6.476981e-4
GO:0001825	blastocyst formation	6.648465e-4
GO:0021797	forebrain anterior/posterior pattern specification	6.656963e-4
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	7.018326e-4
GO:0043314	negative regulation of neutrophil degranulation	7.808992e-4
GO:0035802	adrenal cortex formation	7.948504e-4
GO:0002074	extraocular skeletal muscle development	7.948504e-4
GO:0042273	ribosomal large subunit biogenesis	8.019034e-4
GO:0046102	inosine metabolic process	8.894790e-4
GO:0016573	histone acetylation	9.422816e-4
GO:0007140	male meiosis	9.594259e-4
GO:0010735	positive regulation of transcription via serum response element binding	9.614174e-4
GO:0060896	neural plate pattern specification	9.799109e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.018121e-3
GO:0030851	granulocyte differentiation	1.035966e-3
GO:0031507	heterochromatin formation	1.060482e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	1.109625e-3
GO:0030431	sleep	1.184940e-3
GO:0015670	carbon dioxide transport	1.195536e-3
GO:0033239	negative regulation of cellular amine metabolic process	1.242820e-3
GO:0001829	trophectodermal cell differentiation	1.258818e-3
GO:0014909	smooth muscle cell migration	1.281764e-3
GO:0042428	serotonin metabolic process	1.466389e-3
GO:0071577	zinc ion transmembrane transport	1.481818e-3
GO:0032119	sequestering of zinc ion	1.540840e-3
GO:0006409	tRNA export from nucleus	1.584961e-3
GO:0071169	establishment of protein localization to chromatin	1.584961e-3
GO:0031468	nuclear envelope reassembly	1.584961e-3
GO:0040040	thermosensory behavior	1.611851e-3
GO:0002730	regulation of dendritic cell cytokine production	1.611851e-3
GO:0032319	regulation of Rho GTPase activity	1.613900e-3
GO:0019673	GDP-mannose metabolic process	1.645559e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.655260e-3
GO:0030219	megakaryocyte differentiation	1.659229e-3
GO:0021521	ventral spinal cord interneuron specification	1.694069e-3
GO:0009435	NAD biosynthetic process	1.731742e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.835854e-3
GO:0097107	postsynaptic density assembly	1.835854e-3
GO:0031914	negative regulation of synaptic plasticity	1.835854e-3
GO:0070845	polyubiquitinated misfolded protein transport	1.835854e-3
GO:0048384	retinoic acid receptor signaling pathway	1.847341e-3
GO:0010950	positive regulation of endopeptidase activity	1.866293e-3
GO:0071715	icosanoid transport	1.874354e-3
GO:0060033	anatomical structure regression	1.910299e-3
GO:0045908	negative regulation of vasodilation	1.911964e-3
GO:0030903	notochord development	1.936181e-3
GO:0060124	positive regulation of growth hormone secretion	1.968233e-3
GO:0030828	positive regulation of cGMP biosynthetic process	1.985239e-3
GO:0021697	cerebellar cortex formation	2.007510e-3
GO:0050685	positive regulation of mRNA processing	2.024195e-3
GO:0046498	S-adenosylhomocysteine metabolic process	2.072863e-3
GO:0021515	cell differentiation in spinal cord	2.124936e-3
GO:0043300	regulation of leukocyte degranulation	2.225941e-3
GO:0030902	hindbrain development	2.302367e-3
GO:0033158	regulation of protein import into nucleus, translocation	2.302706e-3
GO:0032774	RNA biosynthetic process	2.358491e-3
GO:0006601	creatine biosynthetic process	2.396398e-3
GO:0010544	negative regulation of platelet activation	2.499162e-3
GO:0046717	acid secretion	2.525320e-3
GO:0030046	parallel actin filament bundle assembly	2.668934e-3
GO:0042694	muscle cell fate specification	2.668934e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	2.694291e-3
GO:0021587	cerebellum morphogenesis	2.766016e-3
GO:0032784	regulation of transcription elongation, DNA-dependent	2.772369e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	2.898044e-3
GO:0045112	integrin biosynthetic process	2.910084e-3
GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	2.910084e-3
GO:0042866	pyruvate biosynthetic process	2.910084e-3
GO:0015747	urate transport	2.916217e-3
GO:0008612	peptidyl-lysine modification to hypusine	2.916217e-3
GO:0007143	female meiosis	2.977467e-3
GO:0060319	primitive erythrocyte differentiation	3.085430e-3
GO:0042053	regulation of dopamine metabolic process	3.086493e-3
GO:0030031	cell projection assembly	3.155171e-3
GO:0006351	transcription, DNA-dependent	3.175968e-3
GO:0018394	peptidyl-lysine acetylation	3.177114e-3
GO:2000772	regulation of cellular senescence	3.310945e-3
GO:0006473	protein acetylation	3.339276e-3
GO:0030970	retrograde protein transport, ER to cytosol	3.364034e-3
GO:0018393	internal peptidyl-lysine acetylation	3.401422e-3
GO:0021549	cerebellum development	3.481749e-3
GO:0045454	cell redox homeostasis	3.563828e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	3.669215e-3
GO:0035611	protein branching point deglutamylation	3.669215e-3
GO:0048663	neuron fate commitment	3.727215e-3
GO:0018364	peptidyl-glutamine methylation	3.737723e-3
GO:0046103	inosine biosynthetic process	3.737723e-3
GO:0006154	adenosine catabolic process	3.737723e-3
GO:0048227	plasma membrane to endosome transport	3.981374e-3
GO:0021528	commissural neuron differentiation in spinal cord	3.981374e-3
GO:0021516	dorsal spinal cord development	4.306356e-3
GO:0045162	clustering of voltage-gated sodium channels	4.346827e-3
GO:0019348	dolichol metabolic process	4.346827e-3
GO:0001840	neural plate development	4.454716e-3
GO:0042136	neurotransmitter biosynthetic process	4.464516e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	4.464516e-3
GO:0034453	microtubule anchoring	4.477718e-3
GO:0090084	negative regulation of inclusion body assembly	4.558234e-3
GO:2000383	regulation of ectoderm development	4.558234e-3
GO:0043543	protein acylation	4.563644e-3
GO:0006290	pyrimidine dimer repair	4.825750e-3
GO:0007352	zygotic specification of dorsal/ventral axis	4.916645e-3
GO:0032321	positive regulation of Rho GTPase activity	4.946513e-3
GO:0042420	dopamine catabolic process	4.961818e-3
GO:0048840	otolith development	4.977790e-3
GO:0042069	regulation of catecholamine metabolic process	5.280366e-3
GO:0051567	histone H3-K9 methylation	5.307952e-3
GO:0034059	response to anoxia	5.480393e-3
GO:0048670	regulation of collateral sprouting	5.499090e-3
GO:0016068	type I hypersensitivity	5.706935e-3
GO:0035621	ER to Golgi ceramide transport	5.706935e-3
GO:0009798	axis specification	5.711670e-3
GO:0072224	metanephric glomerulus development	5.984818e-3
GO:0021575	hindbrain morphogenesis	6.034701e-3
GO:0050891	multicellular organismal water homeostasis	6.081212e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	6.150168e-3
GO:2001076	positive regulation of metanephric ureteric bud development	6.150168e-3
GO:0018065	protein-cofactor linkage	6.150168e-3
GO:0007356	thorax and anterior abdomen determination	6.150168e-3
GO:0090218	positive regulation of lipid kinase activity	6.563241e-3
GO:0035928	rRNA import into mitochondrion	6.691318e-3
GO:0006668	sphinganine-1-phosphate metabolic process	6.691318e-3
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	6.691318e-3
GO:0048570	notochord morphogenesis	6.862669e-3
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	7.115672e-3
GO:0009452	RNA capping	7.223038e-3
GO:0032571	response to vitamin K	7.436684e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	7.436684e-3
GO:2000384	negative regulation of ectoderm development	7.436684e-3
GO:0018993	somatic sex determination	7.491491e-3
GO:0008611	ether lipid biosynthetic process	7.491491e-3
GO:0043457	regulation of cellular respiration	7.787230e-3
GO:0072166	posterior mesonephric tubule development	7.821569e-3
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	7.821569e-3
GO:0051238	sequestering of metal ion	7.873304e-3
GO:0023021	termination of signal transduction	7.873304e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	7.927011e-3
GO:0021794	thalamus development	8.171295e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	8.263002e-3
GO:0060928	atrioventricular node cell development	8.263002e-3
GO:0060929	atrioventricular node cell fate commitment	8.263002e-3
GO:0031119	tRNA pseudouridine synthesis	8.263002e-3
GO:0032782	bile acid secretion	8.263002e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	8.263002e-3
GO:0003342	proepicardium development	8.263002e-3
GO:0003168	cardiac Purkinje fiber cell differentiation	8.263002e-3
GO:0003096	renal sodium ion transport	8.263002e-3
GO:0015761	mannose transport	8.263002e-3
GO:0006837	serotonin transport	8.370684e-3
GO:0050482	arachidonic acid secretion	8.405538e-3
GO:0070309	lens fiber cell morphogenesis	8.743304e-3
GO:0015746	citrate transport	8.967865e-3
GO:0007614	short-term memory	9.217850e-3
GO:0022037	metencephalon development	9.644294e-3
GO:0072015	glomerular visceral epithelial cell development	9.857285e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	9.857285e-3
GO:0015696	ammonium transport	9.950588e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.000096e-2
GO:0051684	maintenance of Golgi location	1.000096e-2
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.000096e-2
GO:2000119	negative regulation of sodium-dependent phosphate transport	1.000096e-2
GO:0071624	positive regulation of granulocyte chemotaxis	1.000096e-2
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	1.000096e-2
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.000096e-2
GO:0019676	ammonia assimilation cycle	1.000096e-2
GO:0002368	B cell cytokine production	1.000096e-2
GO:0032707	negative regulation of interleukin-23 production	1.000096e-2
GO:0042450	arginine biosynthetic process via ornithine	1.000096e-2
GO:0045362	positive regulation of interleukin-1 biosynthetic process	1.000096e-2
GO:0048291	isotype switching to IgG isotypes	1.000096e-2
GO:0007144	female meiosis I	1.014357e-2
GO:0001678	cellular glucose homeostasis	1.027945e-2
GO:0034447	very-low-density lipoprotein particle clearance	1.038359e-2
GO:0090224	regulation of spindle organization	1.052144e-2
GO:0006403	RNA localization	1.069355e-2
GO:0048339	paraxial mesoderm development	1.082552e-2
GO:0048671	negative regulation of collateral sprouting	1.084827e-2
GO:0060123	regulation of growth hormone secretion	1.102284e-2
GO:0021702	cerebellar Purkinje cell differentiation	1.124839e-2
GO:0071157	negative regulation of cell cycle arrest	1.129609e-2
GO:0043302	positive regulation of leukocyte degranulation	1.140192e-2
GO:0032012	regulation of ARF protein signal transduction	1.141599e-2
GO:0042424	catecholamine catabolic process	1.147507e-2
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	1.147507e-2
GO:0001831	trophectodermal cellular morphogenesis	1.147507e-2
GO:0071394	cellular response to testosterone stimulus	1.172243e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.174361e-2
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.180766e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.189867e-2
GO:0006475	internal protein amino acid acetylation	1.191020e-2
GO:0033160	positive regulation of protein import into nucleus, translocation	1.195776e-2
GO:0003091	renal water homeostasis	1.214079e-2
GO:0021997	neural plate axis specification	1.219898e-2
GO:0032855	positive regulation of Rac GTPase activity	1.253762e-2
GO:0060948	cardiac vascular smooth muscle cell development	1.263527e-2
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.263527e-2
GO:0045814	negative regulation of gene expression, epigenetic	1.265970e-2
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.273236e-2
GO:0060729	intestinal epithelial structure maintenance	1.275614e-2
GO:0007418	ventral midline development	1.275614e-2
GO:0021681	cerebellar granular layer development	1.315284e-2
GO:0055012	ventricular cardiac muscle cell differentiation	1.318447e-2
GO:0051351	positive regulation of ligase activity	1.367024e-2
GO:0048340	paraxial mesoderm morphogenesis	1.409282e-2
GO:0043304	regulation of mast cell degranulation	1.434531e-2
GO:0048368	lateral mesoderm development	1.438582e-2
GO:0032792	negative regulation of CREB transcription factor activity	1.446826e-2
GO:0001778	plasma membrane repair	1.446826e-2
GO:0006405	RNA export from nucleus	1.468534e-2
GO:0060163	subpallium neuron fate commitment	1.474487e-2
GO:0060217	hemangioblast cell differentiation	1.474487e-2
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.474487e-2
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.474487e-2
GO:2000016	negative regulation of determination of dorsal identity	1.474487e-2
GO:0006408	snRNA export from nucleus	1.474487e-2
GO:0000073	spindle pole body separation	1.474487e-2
GO:0045799	positive regulation of chromatin assembly or disassembly	1.474487e-2
GO:0022417	protein maturation by protein folding	1.474487e-2
GO:0045299	otolith mineralization	1.474487e-2
GO:0010447	response to acidity	1.494362e-2
GO:0060911	cardiac cell fate commitment	1.517469e-2
GO:0031365	N-terminal protein amino acid modification	1.533315e-2
GO:0010669	epithelial structure maintenance	1.576470e-2
GO:0006884	cell volume homeostasis	1.581944e-2
GO:0033006	regulation of mast cell activation involved in immune response	1.628879e-2
GO:0060215	primitive hemopoiesis	1.634056e-2
GO:0007616	long-term memory	1.664769e-2
GO:0032836	glomerular basement membrane development	1.665246e-2
GO:0072239	metanephric glomerulus vasculature development	1.665741e-2
GO:0051313	attachment of spindle microtubules to chromosome	1.665741e-2
GO:0060923	cardiac muscle cell fate commitment	1.669301e-2
GO:0060971	embryonic heart tube left/right pattern formation	1.687591e-2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.687591e-2
GO:0016191	synaptic vesicle uncoating	1.687591e-2
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	1.687591e-2
GO:0043306	positive regulation of mast cell degranulation	1.690943e-2
GO:0048251	elastic fiber assembly	1.717247e-2
GO:0060177	regulation of angiotensin metabolic process	1.722207e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.741367e-2
GO:0043313	regulation of neutrophil degranulation	1.741367e-2
GO:0015879	carnitine transport	1.778341e-2
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	1.818008e-2
GO:2000774	positive regulation of cellular senescence	1.819913e-2
GO:0090402	oncogene-induced senescence	1.819913e-2
GO:0035986	senescence-associated heterochromatin focus formation	1.819913e-2
GO:0035810	positive regulation of urine volume	1.819913e-2
GO:0001880	Mullerian duct regression	1.832961e-2
GO:0032853	positive regulation of Ran GTPase activity	1.835985e-2
GO:0030322	stabilization of membrane potential	1.835985e-2
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.835985e-2
GO:0072104	glomerular capillary formation	1.836274e-2
GO:0015692	lead ion transport	1.841222e-2
GO:0070627	ferrous iron import	1.841222e-2
GO:0015676	vanadium ion transport	1.841222e-2
GO:0010312	detoxification of zinc ion	1.841222e-2
GO:0045880	positive regulation of smoothened signaling pathway	1.844742e-2
GO:0051865	protein autoubiquitination	1.874797e-2
GO:0003002	regionalization	1.882298e-2
GO:0002886	regulation of myeloid leukocyte mediated immunity	1.924898e-2
GO:0050772	positive regulation of axonogenesis	1.929561e-2
GO:0006824	cobalt ion transport	1.944308e-2
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.946993e-2
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.985779e-2
GO:0060024	rhythmic synaptic transmission	1.985779e-2
GO:0030221	basophil differentiation	2.014796e-2
GO:0021508	floor plate formation	2.014796e-2
GO:0006189	'de novo' IMP biosynthetic process	2.014796e-2
GO:0015824	proline transport	2.019782e-2
GO:0014047	glutamate secretion	2.019782e-2
GO:0016572	histone phosphorylation	2.024949e-2
GO:0060561	apoptosis involved in morphogenesis	2.039129e-2
GO:0032926	negative regulation of activin receptor signaling pathway	2.045019e-2
GO:0042747	circadian sleep/wake cycle, REM sleep	2.052689e-2
GO:0019388	galactose catabolic process	2.052689e-2
GO:0031442	positive regulation of mRNA 3'-end processing	2.058339e-2
GO:0045905	positive regulation of translational termination	2.063203e-2
GO:0045901	positive regulation of translational elongation	2.063203e-2
GO:0051639	actin filament network formation	2.063203e-2
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	2.063203e-2
GO:0030505	inorganic diphosphate transport	2.063203e-2
GO:0006452	translational frameshifting	2.063203e-2
GO:0034653	retinoic acid catabolic process	2.063203e-2
GO:2000381	negative regulation of mesoderm development	2.067116e-2
GO:0065001	specification of axis polarity	2.067116e-2
GO:0010991	negative regulation of SMAD protein complex assembly	2.067116e-2
GO:0030837	negative regulation of actin filament polymerization	2.072141e-2
GO:0035886	vascular smooth muscle cell differentiation	2.157125e-2
GO:0045657	positive regulation of monocyte differentiation	2.163074e-2
GO:0030968	endoplasmic reticulum unfolded protein response	2.167856e-2
GO:0070293	renal absorption	2.221275e-2
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.255754e-2
GO:0033120	positive regulation of RNA splicing	2.259051e-2
GO:0021510	spinal cord development	2.266035e-2
GO:0014056	regulation of acetylcholine secretion	2.350872e-2
GO:0061104	adrenal chromaffin cell differentiation	2.434126e-2
GO:0061103	carotid body glomus cell differentiation	2.434126e-2
GO:0071247	cellular response to chromate	2.434126e-2
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	2.434126e-2
GO:0061102	stomach neuroendocrine cell differentiation	2.434126e-2
GO:0071259	cellular response to magnetism	2.434126e-2
GO:0003359	noradrenergic neuron fate commitment	2.434126e-2
GO:0007400	neuroblast fate determination	2.434126e-2
GO:0000059	protein import into nucleus, docking	2.434126e-2
GO:0034259	negative regulation of Rho GTPase activity	2.434126e-2
GO:0048697	positive regulation of collateral sprouting in absence of injury	2.434126e-2
GO:0060165	regulation of timing of subpallium neuron differentiation	2.434126e-2
GO:0061100	lung neuroendocrine cell differentiation	2.434126e-2
GO:0032849	positive regulation of cellular pH reduction	2.448145e-2
GO:0085029	extracellular matrix assembly	2.467963e-2
GO:0021683	cerebellar granular layer morphogenesis	2.508679e-2
GO:0080164	regulation of nitric oxide metabolic process	2.512144e-2
GO:0070317	negative regulation of G0 to G1 transition	2.512144e-2
GO:0035502	metanephric ureteric bud development	2.512144e-2
GO:0060035	notochord cell development	2.512144e-2
GO:0006882	cellular zinc ion homeostasis	2.537424e-2
GO:2000210	positive regulation of anoikis	2.547187e-2
GO:0072112	glomerular visceral epithelial cell differentiation	2.627671e-2
GO:0060359	response to ammonium ion	2.647480e-2
GO:0021612	facial nerve structural organization	2.748343e-2
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	2.813234e-2
GO:0071333	cellular response to glucose stimulus	2.814998e-2
GO:0033566	gamma-tubulin complex localization	2.840995e-2
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2.840995e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	2.840995e-2
GO:0006235	dTTP biosynthetic process	2.840995e-2
GO:0010966	regulation of phosphate transport	2.840995e-2
GO:0018230	peptidyl-L-cysteine S-palmitoylation	2.840995e-2
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	2.840995e-2
GO:0070574	cadmium ion transmembrane transport	2.848880e-2
GO:0008608	attachment of spindle microtubules to kinetochore	2.848880e-2
GO:0035313	wound healing, spreading of epidermal cells	2.877688e-2
GO:0033083	regulation of immature T cell proliferation	2.908229e-2
GO:0021546	rhombomere development	2.908229e-2
GO:0009649	entrainment of circadian clock	2.912371e-2
GO:0032481	positive regulation of type I interferon production	2.926533e-2
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	2.943509e-2
GO:0000072	M phase specific microtubule process	2.947926e-2
GO:0055075	potassium ion homeostasis	2.948085e-2
GO:0007097	nuclear migration	2.989652e-2
GO:0021517	ventral spinal cord development	3.005197e-2
GO:0051303	establishment of chromosome localization	3.034442e-2
GO:0031584	activation of phospholipase D activity	3.043962e-2
GO:0042363	fat-soluble vitamin catabolic process	3.043962e-2
GO:0034587	piRNA metabolic process	3.060216e-2
GO:0001820	serotonin secretion	3.061349e-2
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	3.064946e-2
GO:0043276	anoikis	3.088729e-2
GO:0021569	rhombomere 3 development	3.088729e-2
GO:0001955	blood vessel maturation	3.088729e-2
GO:0042360	vitamin E metabolic process	3.106497e-2
GO:0031129	inductive cell-cell signaling	3.106497e-2
GO:0007264	small GTPase mediated signal transduction	3.107628e-2
GO:0006449	regulation of translational termination	3.135010e-2
GO:0005981	regulation of glycogen catabolic process	3.146950e-2
GO:0055069	zinc ion homeostasis	3.189796e-2
GO:0006415	translational termination	3.235235e-2
GO:0035912	dorsal aorta morphogenesis	3.269200e-2
GO:0034421	post-translational protein acetylation	3.269200e-2
GO:0046952	ketone body catabolic process	3.269200e-2
GO:0046940	nucleoside monophosphate phosphorylation	3.269200e-2
GO:0033572	transferrin transport	3.269200e-2
GO:0008216	spermidine metabolic process	3.269200e-2
GO:0021979	hypothalamus cell differentiation	3.269200e-2
GO:0030038	contractile actin filament bundle assembly	3.269200e-2
GO:0090234	regulation of kinetochore assembly	3.291018e-2
GO:0090169	regulation of spindle assembly	3.291018e-2
GO:2000124	regulation of endocannabinoid signaling pathway	3.291018e-2
GO:0022616	DNA strand elongation	3.291018e-2
GO:0003056	regulation of vascular smooth muscle contraction	3.291018e-2
GO:0051292	nuclear pore complex assembly	3.348141e-2
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	3.348141e-2
GO:0006438	valyl-tRNA aminoacylation	3.348141e-2
GO:0032933	SREBP-mediated signaling pathway	3.355352e-2
GO:0021523	somatic motor neuron differentiation	3.355352e-2
GO:0015891	siderophore transport	3.357140e-2
GO:0000415	negative regulation of histone H3-K36 methylation	3.357140e-2
GO:0001830	trophectodermal cell fate commitment	3.357140e-2
GO:0043923	positive regulation by host of viral transcription	3.359909e-2
GO:0007090	regulation of S phase of mitotic cell cycle	3.363239e-2
GO:0060032	notochord regression	3.383944e-2
GO:0032613	interleukin-10 production	3.383944e-2
GO:0045906	negative regulation of vasoconstriction	3.387624e-2
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	3.387624e-2
GO:0015937	coenzyme A biosynthetic process	3.390002e-2
GO:0034498	early endosome to Golgi transport	3.390512e-2
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	3.390512e-2
GO:0021530	spinal cord oligodendrocyte cell fate specification	3.390512e-2
GO:0009953	dorsal/ventral pattern formation	3.397682e-2
GO:0072488	ammonium transmembrane transport	3.545847e-2
GO:0009264	deoxyribonucleotide catabolic process	3.545847e-2
GO:0042733	embryonic digit morphogenesis	3.627837e-2
GO:0043624	cellular protein complex disassembly	3.638947e-2
GO:0010665	regulation of cardiac muscle cell apoptosis	3.692693e-2
GO:0070584	mitochondrion morphogenesis	3.739984e-2
GO:0006364	rRNA processing	3.747501e-2
GO:0021707	cerebellar granule cell differentiation	3.757792e-2
GO:0035176	social behavior	3.759008e-2
GO:0001824	blastocyst development	3.795818e-2
GO:0043967	histone H4 acetylation	3.869058e-2
GO:2000015	regulation of determination of dorsal identity	3.879108e-2
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	3.879108e-2
GO:0010667	negative regulation of cardiac muscle cell apoptosis	3.919402e-2
GO:0009113	purine base biosynthetic process	3.932515e-2
GO:0007182	common-partner SMAD protein phosphorylation	3.957427e-2
GO:0042942	D-serine transport	4.009888e-2
GO:0034725	DNA replication-dependent nucleosome disassembly	4.009888e-2
GO:0051160	L-xylitol catabolic process	4.009888e-2
GO:0071352	cellular response to interleukin-2	4.009888e-2
GO:0046604	positive regulation of mitotic centrosome separation	4.009888e-2
GO:0046370	fructose biosynthetic process	4.009888e-2
GO:0034276	kynurenic acid biosynthetic process	4.009888e-2
GO:0000027	ribosomal large subunit assembly	4.009888e-2
GO:0002534	cytokine production involved in inflammatory response	4.009888e-2
GO:0002357	defense response to tumor cell	4.009888e-2
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	4.009888e-2
GO:0006062	sorbitol catabolic process	4.009888e-2
GO:0060026	convergent extension	4.046004e-2
GO:0031333	negative regulation of protein complex assembly	4.122744e-2
GO:0043586	tongue development	4.134537e-2
GO:0055089	fatty acid homeostasis	4.135120e-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.168434e-2
GO:0006999	nuclear pore organization	4.168434e-2
GO:0002524	hypersensitivity	4.168434e-2
GO:0045862	positive regulation of proteolysis	4.176391e-2