Novel motif:66

name:	motif66_ACCGRTCA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0000075	cell cycle checkpoint	1.015005e-9
GO:0016071	mRNA metabolic process	1.376030e-9
GO:0051320	S phase	1.423869e-9
GO:0016574	histone ubiquitination	1.484186e-9
GO:0065004	protein-DNA complex assembly	1.951621e-9
GO:0006334	nucleosome assembly	6.584413e-9
GO:0006259	DNA metabolic process	7.660741e-9
GO:0031497	chromatin assembly	2.048582e-8
GO:0043316	cytotoxic T cell degranulation	4.513280e-8
GO:0033314	mitotic cell cycle DNA replication checkpoint	7.958157e-8
GO:0022403	cell cycle phase	8.393494e-8
GO:0006323	DNA packaging	9.902063e-8
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	1.030336e-7
GO:0006281	DNA repair	1.043887e-7
GO:0000278	mitotic cell cycle	1.190387e-7
GO:0006807	nitrogen compound metabolic process	1.476675e-7
GO:0010564	regulation of cell cycle process	1.605664e-7
GO:0071156	regulation of cell cycle arrest	1.674863e-7
GO:0070535	histone H2A K63-linked ubiquitination	2.376011e-7
GO:0006397	mRNA processing	2.390791e-7
GO:0071103	DNA conformation change	2.684460e-7
GO:0046605	regulation of centrosome cycle	3.915154e-7
GO:0051438	regulation of ubiquitin-protein ligase activity	4.930716e-7
GO:0071824	protein-DNA complex subunit organization	5.633217e-7
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.968685e-7
GO:0051340	regulation of ligase activity	6.919717e-7
GO:0034641	cellular nitrogen compound metabolic process	7.055903e-7
GO:0006139	nucleobase-containing compound metabolic process	8.403345e-7
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	1.179277e-6
GO:0021905	forebrain-midbrain boundary formation	1.179277e-6
GO:0003322	pancreatic A cell development	1.179277e-6
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.179277e-6
GO:0000398	nuclear mRNA splicing, via spliceosome	1.190486e-6
GO:0000375	RNA splicing, via transesterification reactions	1.234728e-6
GO:0021903	rostrocaudal neural tube patterning	1.644347e-6
GO:0071934	thiamine transmembrane transport	1.712841e-6
GO:0090304	nucleic acid metabolic process	1.741423e-6
GO:0034728	nucleosome organization	2.013530e-6
GO:0006369	termination of RNA polymerase II transcription	2.061609e-6
GO:0060066	oviduct development	2.102654e-6
GO:0032055	negative regulation of translation in response to stress	2.109817e-6
GO:0007093	mitotic cell cycle checkpoint	2.258713e-6
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	2.806293e-6
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	3.146997e-6
GO:0022402	cell cycle process	3.368791e-6
GO:0010498	proteasomal protein catabolic process	3.544683e-6
GO:0034622	cellular macromolecular complex assembly	3.547129e-6
GO:0051443	positive regulation of ubiquitin-protein ligase activity	3.703590e-6
GO:0009452	RNA capping	4.520920e-6
GO:0051276	chromosome organization	4.620756e-6
GO:0051983	regulation of chromosome segregation	4.676151e-6
GO:0044265	cellular macromolecule catabolic process	4.735533e-6
GO:0006348	chromatin silencing at telomere	4.780427e-6
GO:0034621	cellular macromolecular complex subunit organization	4.950393e-6
GO:0061307	cardiac neural crest cell differentiation involved in heart development	4.984991e-6
GO:0051351	positive regulation of ligase activity	5.409933e-6
GO:0051325	interphase	6.619597e-6
GO:0042347	negative regulation of NF-kappaB import into nucleus	7.028175e-6
GO:0000084	S phase of mitotic cell cycle	7.736089e-6
GO:0033523	histone H2B ubiquitination	8.301671e-6
GO:0045019	negative regulation of nitric oxide biosynthetic process	8.446551e-6
GO:0051131	chaperone-mediated protein complex assembly	8.807469e-6
GO:0044237	cellular metabolic process	9.313028e-6
GO:0006695	cholesterol biosynthetic process	1.028978e-5
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.045064e-5
GO:0044248	cellular catabolic process	1.055984e-5
GO:0044238	primary metabolic process	1.088834e-5
GO:0006473	protein acetylation	1.098853e-5
GO:0006333	chromatin assembly or disassembly	1.174697e-5
GO:0008380	RNA splicing	1.176009e-5
GO:0006396	RNA processing	1.195263e-5
GO:0002553	histamine secretion by mast cell	1.234565e-5
GO:0046853	inositol or phosphatidylinositol phosphorylation	1.238657e-5
GO:0008299	isoprenoid biosynthetic process	1.296626e-5
GO:0006398	histone mRNA 3'-end processing	1.331265e-5
GO:0006366	transcription from RNA polymerase II promoter	1.358306e-5
GO:0051220	cytoplasmic sequestering of protein	1.388295e-5
GO:0008054	cyclin catabolic process	1.563779e-5
GO:0033365	protein localization to organelle	1.779083e-5
GO:0070507	regulation of microtubule cytoskeleton organization	1.844383e-5
GO:0042994	cytoplasmic sequestering of transcription factor	2.018306e-5
GO:0048172	regulation of short-term neuronal synaptic plasticity	2.093547e-5
GO:0006370	mRNA capping	2.271443e-5
GO:0051567	histone H3-K9 methylation	2.462366e-5
GO:0021796	cerebral cortex regionalization	2.480405e-5
GO:0045540	regulation of cholesterol biosynthetic process	2.681717e-5
GO:0031576	G2/M transition checkpoint	2.693894e-5
GO:0000072	M phase specific microtubule process	2.861579e-5
GO:0002344	B cell affinity maturation	2.875968e-5
GO:0000492	box C/D snoRNP assembly	2.913618e-5
GO:0006353	transcription termination, DNA-dependent	2.990033e-5
GO:0006626	protein targeting to mitochondrion	3.118781e-5
GO:0043299	leukocyte degranulation	3.159035e-5
GO:0016126	sterol biosynthetic process	3.314726e-5
GO:0018394	peptidyl-lysine acetylation	3.408598e-5
GO:0071777	positive regulation of cell cycle cytokinesis	3.718932e-5
GO:0003266	regulation of secondary heart field cardioblast proliferation	3.773969e-5
GO:0000090	mitotic anaphase	3.909973e-5
GO:0072655	establishment of protein localization in mitochondrion	3.943165e-5
GO:0006379	mRNA cleavage	4.001988e-5
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	4.024088e-5
GO:0031117	positive regulation of microtubule depolymerization	4.024088e-5
GO:0031124	mRNA 3'-end processing	4.037112e-5
GO:0018393	internal peptidyl-lysine acetylation	4.385582e-5
GO:0007049	cell cycle	4.478954e-5
GO:0014719	satellite cell activation	4.575695e-5
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	4.575695e-5
GO:0016090	prenol metabolic process	4.578946e-5
GO:0048285	organelle fission	4.641991e-5
GO:0033152	immunoglobulin V(D)J recombination	4.711648e-5
GO:0051464	positive regulation of cortisol secretion	5.115060e-5
GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep	5.115060e-5
GO:0006974	response to DNA damage stimulus	5.280677e-5
GO:0016567	protein ubiquitination	5.652017e-5
GO:0007506	gonadal mesoderm development	5.669136e-5
GO:0008610	lipid biosynthetic process	5.675972e-5
GO:0002448	mast cell mediated immunity	5.688520e-5
GO:0060968	regulation of gene silencing	5.743113e-5
GO:0000087	M phase of mitotic cell cycle	6.092507e-5
GO:0000076	DNA replication checkpoint	6.215755e-5
GO:0007017	microtubule-based process	6.323662e-5
GO:0043149	stress fiber assembly	6.635369e-5
GO:0070585	protein localization in mitochondrion	6.876418e-5
GO:0000216	M/G1 transition of mitotic cell cycle	6.886938e-5
GO:0070986	left/right axis specification	6.974636e-5
GO:0043555	regulation of translation in response to stress	7.226579e-5
GO:0051322	anaphase	7.331420e-5
GO:0006475	internal protein amino acid acetylation	7.350605e-5
GO:0051444	negative regulation of ubiquitin-protein ligase activity	7.609670e-5
GO:0007067	mitosis	7.707911e-5
GO:0015755	fructose transport	8.308032e-5
GO:0000733	DNA strand renaturation	8.523874e-5
GO:0032543	mitochondrial translation	9.363415e-5
GO:0000279	M phase	9.383571e-5
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.494905e-5
GO:0044249	cellular biosynthetic process	1.005963e-4
GO:0044257	cellular protein catabolic process	1.086114e-4
GO:0009057	macromolecule catabolic process	1.116757e-4
GO:0043320	natural killer cell degranulation	1.286898e-4
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	1.299829e-4
GO:0006607	NLS-bearing substrate import into nucleus	1.313367e-4
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.334675e-4
GO:0002339	B cell selection	1.334675e-4
GO:0006310	DNA recombination	1.336262e-4
GO:0021983	pituitary gland development	1.409416e-4
GO:0031398	positive regulation of protein ubiquitination	1.457105e-4
GO:0043543	protein acylation	1.516224e-4
GO:2000195	negative regulation of female gonad development	1.519385e-4
GO:0010912	positive regulation of isomerase activity	1.616268e-4
GO:0031570	DNA integrity checkpoint	1.657169e-4
GO:0006325	chromatin organization	1.706261e-4
GO:2000194	regulation of female gonad development	1.706705e-4
GO:0000073	spindle pole body separation	1.729573e-4
GO:0001546	preantral ovarian follicle growth	1.729573e-4
GO:0006511	ubiquitin-dependent protein catabolic process	1.753458e-4
GO:0042992	negative regulation of transcription factor import into nucleus	1.766872e-4
GO:0051329	interphase of mitotic cell cycle	1.836762e-4
GO:0016573	histone acetylation	1.861313e-4
GO:0006283	transcription-coupled nucleotide-excision repair	1.864812e-4
GO:0009058	biosynthetic process	1.904677e-4
GO:0021523	somatic motor neuron differentiation	1.922699e-4
GO:0060236	regulation of mitotic spindle organization	1.968144e-4
GO:0048753	pigment granule organization	1.991433e-4
GO:0007059	chromosome segregation	2.001417e-4
GO:0000077	DNA damage checkpoint	2.047004e-4
GO:0060972	left/right pattern formation	2.060169e-4
GO:0006996	organelle organization	2.068884e-4
GO:0032886	regulation of microtubule-based process	2.110532e-4
GO:0046108	uridine metabolic process	2.385168e-4
GO:0014842	regulation of satellite cell proliferation	2.385168e-4
GO:0050973	detection of mechanical stimulus involved in equilibrioception	2.454808e-4
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.514481e-4
GO:0007346	regulation of mitotic cell cycle	2.531477e-4
GO:0051726	regulation of cell cycle	2.560272e-4
GO:0051899	membrane depolarization	2.570056e-4
GO:0010025	wax biosynthetic process	2.590774e-4
GO:0046459	short-chain fatty acid metabolic process	2.704152e-4
GO:0019941	modification-dependent protein catabolic process	2.711522e-4
GO:0032438	melanosome organization	2.735065e-4
GO:0031123	RNA 3'-end processing	2.846916e-4
GO:0090307	spindle assembly involved in mitosis	2.883588e-4
GO:0046485	ether lipid metabolic process	2.883588e-4
GO:0034436	glycoprotein transport	2.895271e-4
GO:0031642	negative regulation of myelination	2.895271e-4
GO:0009720	detection of hormone stimulus	2.895271e-4
GO:0008152	metabolic process	2.906676e-4
GO:0035461	vitamin transmembrane transport	2.990853e-4
GO:0006986	response to unfolded protein	3.156542e-4
GO:0008611	ether lipid biosynthetic process	3.173613e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3.244374e-4
GO:0019441	tryptophan catabolic process to kynurenine	3.375061e-4
GO:0042982	amyloid precursor protein metabolic process	3.415867e-4
GO:0051603	proteolysis involved in cellular protein catabolic process	3.435125e-4
GO:0030317	sperm motility	3.525224e-4
GO:0051301	cell division	3.605827e-4
GO:0016139	glycoside catabolic process	3.696691e-4
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.724927e-4
GO:0070682	proteasome regulatory particle assembly	3.742363e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	3.920424e-4
GO:0006605	protein targeting	4.053206e-4
GO:0090181	regulation of cholesterol metabolic process	4.155215e-4
GO:0001711	endodermal cell fate commitment	4.164151e-4
GO:0045338	farnesyl diphosphate metabolic process	4.171706e-4
GO:0006694	steroid biosynthetic process	4.235265e-4
GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	4.253555e-4
GO:0035754	B cell chemotaxis	4.253555e-4
GO:0002518	lymphocyte chemotaxis across high endothelial venule	4.253555e-4
GO:0043438	acetoacetic acid metabolic process	4.281741e-4
GO:0006595	polyamine metabolic process	4.325899e-4
GO:0017038	protein import	4.331488e-4
GO:0043632	modification-dependent macromolecule catabolic process	4.369740e-4
GO:0006302	double-strand break repair	4.458056e-4
GO:0006573	valine metabolic process	4.487058e-4
GO:0002551	mast cell chemotaxis	5.242257e-4
GO:0060554	induction of necroptosis of activated-T cells	5.456601e-4
GO:0032057	negative regulation of translational initiation in response to stress	5.577300e-4
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	5.715405e-4
GO:0061303	cornea development in camera-type eye	5.715405e-4
GO:0051462	regulation of cortisol secretion	5.817152e-4
GO:0016570	histone modification	5.937263e-4
GO:0030219	megakaryocyte differentiation	6.108270e-4
GO:0019605	butyrate metabolic process	6.294801e-4
GO:0033059	cellular pigmentation	6.487506e-4
GO:0032808	lacrimal gland development	6.615673e-4
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	6.822706e-4
GO:0008625	induction of apoptosis via death domain receptors	6.838998e-4
GO:0019509	L-methionine salvage from methylthioadenosine	6.904950e-4
GO:0017121	phospholipid scrambling	6.995762e-4
GO:0006659	phosphatidylserine biosynthetic process	7.152107e-4
GO:0002071	glandular epithelial cell maturation	7.152389e-4
GO:0006435	threonyl-tRNA aminoacylation	7.187438e-4
GO:0009064	glutamine family amino acid metabolic process	7.210039e-4
GO:0016569	covalent chromatin modification	7.248509e-4
GO:0009056	catabolic process	7.288416e-4
GO:0016032	viral reproduction	7.329086e-4
GO:0010824	regulation of centrosome duplication	7.344691e-4
GO:0014821	phasic smooth muscle contraction	7.438901e-4
GO:0001714	endodermal cell fate specification	7.702353e-4
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	7.851538e-4
GO:0007352	zygotic specification of dorsal/ventral axis	7.851538e-4
GO:0034394	protein localization at cell surface	7.864745e-4
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	7.975802e-4
GO:0031572	G2/M transition DNA damage checkpoint	8.038446e-4
GO:0001706	endoderm formation	8.177479e-4
GO:0070189	kynurenine metabolic process	8.229449e-4
GO:0035966	response to topologically incorrect protein	8.267980e-4
GO:0090321	positive regulation of chylomicron remnant clearance	8.444571e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.520783e-4
GO:0000085	G2 phase of mitotic cell cycle	8.813906e-4
GO:0003264	regulation of cardioblast proliferation	9.197397e-4
GO:0035315	hair cell differentiation	9.403399e-4
GO:0010825	positive regulation of centrosome duplication	9.538184e-4
GO:0030163	protein catabolic process	9.591311e-4
GO:0032446	protein modification by small protein conjugation	9.641065e-4
GO:0048505	regulation of timing of cell differentiation	1.019000e-3
GO:0043631	RNA polyadenylation	1.042906e-3
GO:0071985	multivesicular body sorting pathway	1.053869e-3
GO:2000020	positive regulation of male gonad development	1.060274e-3
GO:0000723	telomere maintenance	1.061416e-3
GO:0006001	fructose catabolic process	1.069027e-3
GO:0001676	long-chain fatty acid metabolic process	1.069536e-3
GO:0035987	endodermal cell differentiation	1.069731e-3
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	1.111982e-3
GO:0050684	regulation of mRNA processing	1.113031e-3
GO:0045650	negative regulation of macrophage differentiation	1.140652e-3
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	1.148847e-3
GO:0006768	biotin metabolic process	1.148847e-3
GO:0006552	leucine catabolic process	1.148847e-3
GO:0006378	mRNA polyadenylation	1.178151e-3
GO:0072594	establishment of protein localization to organelle	1.199828e-3
GO:0021707	cerebellar granule cell differentiation	1.237817e-3
GO:0019853	L-ascorbic acid biosynthetic process	1.246801e-3
GO:0010986	positive regulation of lipoprotein particle clearance	1.246801e-3
GO:0032467	positive regulation of cytokinesis	1.282144e-3
GO:0055094	response to lipoprotein stimulus	1.297008e-3
GO:0046666	retinal cell programmed cell death	1.309246e-3
GO:0070647	protein modification by small protein conjugation or removal	1.316683e-3
GO:0002329	pre-B cell differentiation	1.332472e-3
GO:0051256	spindle midzone assembly involved in mitosis	1.354179e-3
GO:0042339	keratan sulfate metabolic process	1.425045e-3
GO:0001821	histamine secretion	1.437057e-3
GO:0003272	endocardial cushion formation	1.463798e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.487346e-3
GO:0046835	carbohydrate phosphorylation	1.492902e-3
GO:0046590	embryonic leg morphogenesis	1.492902e-3
GO:0030432	peristalsis	1.527716e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	1.534210e-3
GO:2000243	positive regulation of reproductive process	1.549162e-3
GO:0006103	2-oxoglutarate metabolic process	1.553965e-3
GO:0009081	branched chain family amino acid metabolic process	1.562994e-3
GO:0000082	G1/S transition of mitotic cell cycle	1.570380e-3
GO:0070345	negative regulation of fat cell proliferation	1.587071e-3
GO:0009785	blue light signaling pathway	1.588567e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	1.632338e-3
GO:0072274	metanephric glomerular basement membrane development	1.632338e-3
GO:0048677	axon extension involved in regeneration	1.632338e-3
GO:0007113	endomitotic cell cycle	1.632338e-3
GO:0009063	cellular amino acid catabolic process	1.663166e-3
GO:0043303	mast cell degranulation	1.702855e-3
GO:0060216	definitive hemopoiesis	1.706830e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	1.721748e-3
GO:0060359	response to ammonium ion	1.730908e-3
GO:0001831	trophectodermal cellular morphogenesis	1.782638e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1.800882e-3
GO:0006895	Golgi to endosome transport	1.817257e-3
GO:0008654	phospholipid biosynthetic process	1.830940e-3
GO:0009310	amine catabolic process	1.887348e-3
GO:0009067	aspartate family amino acid biosynthetic process	1.960200e-3
GO:0007006	mitochondrial membrane organization	1.987531e-3
GO:0060409	positive regulation of acetylcholine metabolic process	2.024457e-3
GO:0007051	spindle organization	2.050234e-3
GO:0051791	medium-chain fatty acid metabolic process	2.092250e-3
GO:0031468	nuclear envelope reassembly	2.092250e-3
GO:0061072	iris morphogenesis	2.106338e-3
GO:0016476	regulation of embryonic cell shape	2.145367e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	2.168851e-3
GO:0043409	negative regulation of MAPKKK cascade	2.182620e-3
GO:0016137	glycoside metabolic process	2.289041e-3
GO:0010952	positive regulation of peptidase activity	2.297415e-3
GO:0009083	branched chain family amino acid catabolic process	2.347452e-3
GO:0032200	telomere organization	2.388028e-3
GO:2000227	negative regulation of pancreatic A cell differentiation	2.390066e-3
GO:2000978	negative regulation of forebrain neuron differentiation	2.390066e-3
GO:0048014	Tie receptor signaling pathway	2.390066e-3
GO:0046331	lateral inhibition	2.390066e-3
GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	2.390066e-3
GO:0051608	histamine transport	2.402997e-3
GO:0018205	peptidyl-lysine modification	2.409829e-3
GO:0043923	positive regulation by host of viral transcription	2.427493e-3
GO:0008228	opsonization	2.450741e-3
GO:0046477	glycosylceramide catabolic process	2.483723e-3
GO:0045654	positive regulation of megakaryocyte differentiation	2.483723e-3
GO:0002052	positive regulation of neuroblast proliferation	2.494534e-3
GO:0035590	purinergic nucleotide receptor signaling pathway	2.573373e-3
GO:0046496	nicotinamide nucleotide metabolic process	2.622607e-3
GO:0030261	chromosome condensation	2.622680e-3
GO:0000018	regulation of DNA recombination	2.650970e-3
GO:0045746	negative regulation of Notch signaling pathway	2.652294e-3
GO:2000018	regulation of male gonad development	2.679134e-3
GO:0031133	regulation of axon diameter	2.690663e-3
GO:0021558	trochlear nerve development	2.696888e-3
GO:0006533	aspartate catabolic process	2.701207e-3
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	2.701207e-3
GO:0035026	leading edge cell differentiation	2.701207e-3
GO:0031579	membrane raft organization	2.719990e-3
GO:0035852	horizontal cell localization	2.761125e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	2.761125e-3
GO:0035849	nephric duct elongation	2.761125e-3
GO:0035502	metanephric ureteric bud development	2.761125e-3
GO:0035846	oviduct epithelium development	2.761125e-3
GO:0035847	uterine epithelium development	2.761125e-3
GO:0016525	negative regulation of angiogenesis	2.779834e-3
GO:0007005	mitochondrion organization	2.781035e-3
GO:0032861	activation of Rap GTPase activity	2.805807e-3
GO:0006601	creatine biosynthetic process	2.825519e-3
GO:0042987	amyloid precursor protein catabolic process	2.876396e-3
GO:0021877	forebrain neuron fate commitment	2.876396e-3
GO:0043388	positive regulation of DNA binding	2.982645e-3
GO:0006926	virus-infected cell apoptosis	2.986345e-3
GO:0007018	microtubule-based movement	3.095909e-3
GO:0021536	diencephalon development	3.097728e-3
GO:0003175	tricuspid valve development	3.106668e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	3.149978e-3
GO:0046968	peptide antigen transport	3.177535e-3
GO:0033151	V(D)J recombination	3.287556e-3
GO:2000833	positive regulation of steroid hormone secretion	3.307059e-3
GO:0006839	mitochondrial transport	3.404273e-3
GO:0006020	inositol metabolic process	3.424912e-3
GO:0043484	regulation of RNA splicing	3.427143e-3
GO:0045040	protein import into mitochondrial outer membrane	3.589222e-3
GO:0000188	inactivation of MAPK activity	3.644034e-3
GO:0046504	glycerol ether biosynthetic process	3.677194e-3
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	3.691625e-3
GO:0009912	auditory receptor cell fate commitment	3.691625e-3
GO:0051365	cellular response to potassium ion starvation	3.705190e-3
GO:0043148	mitotic spindle stabilization	3.716895e-3
GO:0051355	proprioception involved in equilibrioception	3.716895e-3
GO:0045947	negative regulation of translational initiation	3.726310e-3
GO:0006391	transcription initiation from mitochondrial promoter	3.780617e-3
GO:0006189	'de novo' IMP biosynthetic process	3.780617e-3
GO:0007595	lactation	3.912474e-3
GO:0072348	sulfur compound transport	3.953786e-3
GO:0000819	sister chromatid segregation	3.954999e-3
GO:0016445	somatic diversification of immunoglobulins	3.992694e-3
GO:0034763	negative regulation of transmembrane transport	4.048547e-3
GO:0009072	aromatic amino acid family metabolic process	4.183655e-3
GO:0016070	RNA metabolic process	4.203556e-3
GO:0043558	regulation of translational initiation in response to stress	4.242343e-3
GO:0031161	phosphatidylinositol catabolic process	4.270512e-3
GO:0007321	sperm displacement	4.270512e-3
GO:0044260	cellular macromolecule metabolic process	4.423030e-3
GO:0006271	DNA strand elongation involved in DNA replication	4.429378e-3
GO:0032185	septin cytoskeleton organization	4.433802e-3
GO:0031396	regulation of protein ubiquitination	4.517943e-3
GO:0030851	granulocyte differentiation	4.530079e-3
GO:0014074	response to purine-containing compound	4.539800e-3
GO:0010994	free ubiquitin chain polymerization	4.553070e-3
GO:0007156	homophilic cell adhesion	4.715752e-3
GO:0051255	spindle midzone assembly	4.718111e-3
GO:0007182	common-partner SMAD protein phosphorylation	4.718111e-3
GO:0042308	negative regulation of protein import into nucleus	4.749222e-3
GO:0006658	phosphatidylserine metabolic process	4.785819e-3
GO:0043933	macromolecular complex subunit organization	4.809876e-3
GO:0002639	positive regulation of immunoglobulin production	4.928968e-3
GO:0045055	regulated secretory pathway	5.054118e-3
GO:0009086	methionine biosynthetic process	5.168980e-3
GO:0008628	induction of apoptosis by hormones	5.233708e-3
GO:0006244	pyrimidine nucleotide catabolic process	5.337059e-3
GO:0035854	eosinophil fate commitment	5.350139e-3
GO:0030222	eosinophil differentiation	5.350139e-3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	5.351383e-3
GO:0072334	UDP-galactose transmembrane transport	5.431396e-3
GO:0071242	cellular response to ammonium ion	5.431396e-3
GO:0006265	DNA topological change	5.548617e-3
GO:0051775	response to redox state	5.645778e-3
GO:0045608	negative regulation of auditory receptor cell differentiation	5.645778e-3
GO:0014827	intestine smooth muscle contraction	5.725415e-3
GO:0009637	response to blue light	5.725415e-3
GO:0010984	regulation of lipoprotein particle clearance	5.728086e-3
GO:0007029	endoplasmic reticulum organization	5.775824e-3
GO:0032507	maintenance of protein location in cell	5.810715e-3
GO:0045814	negative regulation of gene expression, epigenetic	5.838649e-3
GO:0006637	acyl-CoA metabolic process	5.847701e-3
GO:0006740	NADPH regeneration	5.965023e-3
GO:0007080	mitotic metaphase plate congression	6.165801e-3
GO:0045870	positive regulation of retroviral genome replication	6.192715e-3
GO:0002769	natural killer cell inhibitory signaling pathway	6.192715e-3
GO:2000045	regulation of G1/S transition of mitotic cell cycle	6.194153e-3
GO:0006733	oxidoreduction coenzyme metabolic process	6.224483e-3
GO:0010745	negative regulation of macrophage derived foam cell differentiation	6.242144e-3
GO:0032201	telomere maintenance via semi-conservative replication	6.278708e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	6.319773e-3
GO:0006479	protein methylation	6.369499e-3
GO:0097084	vascular smooth muscle cell development	6.392745e-3
GO:0060040	retinal bipolar neuron differentiation	6.392745e-3
GO:0006116	NADH oxidation	6.422844e-3
GO:0065003	macromolecular complex assembly	6.434228e-3
GO:0021872	forebrain generation of neurons	6.458227e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	6.475258e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.545022e-3
GO:0006000	fructose metabolic process	6.580993e-3
GO:0000731	DNA synthesis involved in DNA repair	6.629327e-3
GO:0007063	regulation of sister chromatid cohesion	6.635399e-3
GO:0035587	purinergic receptor signaling pathway	6.768591e-3
GO:0000070	mitotic sister chromatid segregation	6.854864e-3
GO:0021557	oculomotor nerve development	6.920727e-3
GO:0006662	glycerol ether metabolic process	7.012934e-3
GO:0051225	spindle assembly	7.052410e-3
GO:0006536	glutamate metabolic process	7.124720e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	7.156969e-3
GO:0002456	T cell mediated immunity	7.213560e-3
GO:0071844	cellular component assembly at cellular level	7.353416e-3
GO:0045008	depyrimidination	7.489155e-3
GO:0001957	intramembranous ossification	7.526189e-3
GO:0090084	negative regulation of inclusion body assembly	7.564464e-3
GO:0051313	attachment of spindle microtubules to chromosome	7.637837e-3
GO:0030856	regulation of epithelial cell differentiation	7.757317e-3
GO:0021984	adenohypophysis development	7.769833e-3
GO:0003310	pancreatic A cell differentiation	7.883787e-3
GO:0031952	regulation of protein autophosphorylation	7.925306e-3
GO:0033344	cholesterol efflux	8.032201e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	8.064408e-3
GO:0090068	positive regulation of cell cycle process	8.106747e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	8.218315e-3
GO:0021517	ventral spinal cord development	8.256502e-3
GO:0048015	phosphatidylinositol-mediated signaling	8.305955e-3
GO:0021683	cerebellar granular layer morphogenesis	8.341430e-3
GO:0033238	regulation of cellular amine metabolic process	8.349010e-3
GO:0001704	formation of primary germ layer	8.372110e-3
GO:0006734	NADH metabolic process	8.403069e-3
GO:0055107	Golgi to secretory granule transport	8.553216e-3
GO:0090149	membrane fission involved in mitochondrial fission	8.553216e-3
GO:0051160	L-xylitol catabolic process	8.553216e-3
GO:0046370	fructose biosynthetic process	8.553216e-3
GO:0006062	sorbitol catabolic process	8.553216e-3
GO:0003374	dynamin polymerization involved in mitochondrial fission	8.553216e-3
GO:0061038	uterus morphogenesis	8.761776e-3
GO:0022616	DNA strand elongation	8.771710e-3
GO:0032536	regulation of cell projection size	8.914209e-3
GO:0019852	L-ascorbic acid metabolic process	8.963139e-3
GO:0000910	cytokinesis	9.024900e-3
GO:0048617	embryonic foregut morphogenesis	9.116592e-3
GO:0006551	leucine metabolic process	9.228968e-3
GO:0032621	interleukin-18 production	9.228968e-3
GO:0050957	equilibrioception	9.281597e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	9.343906e-3
GO:0006312	mitotic recombination	9.344953e-3
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	9.512153e-3
GO:0022605	oogenesis stage	9.636703e-3
GO:2000831	regulation of steroid hormone secretion	9.653778e-3
GO:0006913	nucleocytoplasmic transport	9.694606e-3
GO:0044281	small molecule metabolic process	9.710730e-3
GO:0031557	induction of programmed cell death in response to chemical stimulus	9.834848e-3
GO:0043280	positive regulation of caspase activity	9.986152e-3
GO:0032237	activation of store-operated calcium channel activity	1.004592e-2
GO:2000602	regulation of interphase of mitotic cell cycle	1.009437e-2
GO:0042668	auditory receptor cell fate determination	1.013519e-2
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	1.014569e-2
GO:2000826	regulation of heart morphogenesis	1.016633e-2
GO:0002200	somatic diversification of immune receptors	1.019356e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006334	nucleosome assembly	1.635400e-17
GO:0034728	nucleosome organization	9.386695e-17
GO:0031497	chromatin assembly	3.940995e-15
GO:0065004	protein-DNA complex assembly	8.888518e-15
GO:0006333	chromatin assembly or disassembly	2.062082e-14
GO:0071824	protein-DNA complex subunit organization	2.292289e-14
GO:0007283	spermatogenesis	8.733324e-14
GO:0071103	DNA conformation change	2.764090e-13
GO:0006323	DNA packaging	1.168165e-12
GO:0051276	chromosome organization	1.075129e-10
GO:0007276	gamete generation	1.483458e-10
GO:0006986	response to unfolded protein	4.203903e-10
GO:0060968	regulation of gene silencing	4.498855e-10
GO:0030970	retrograde protein transport, ER to cytosol	1.766923e-9
GO:0090307	spindle assembly involved in mitosis	2.273360e-9
GO:0006325	chromatin organization	3.030007e-9
GO:0019953	sexual reproduction	4.463288e-9
GO:0030968	endoplasmic reticulum unfolded protein response	2.089634e-8
GO:0035966	response to topologically incorrect protein	3.319583e-8
GO:0043503	skeletal muscle fiber adaptation	7.733978e-8
GO:0030210	heparin biosynthetic process	1.551777e-7
GO:0006259	DNA metabolic process	1.685968e-7
GO:0071777	positive regulation of cell cycle cytokinesis	1.765594e-7
GO:0035967	cellular response to topologically incorrect protein	1.981100e-7
GO:0070925	organelle assembly	3.433034e-7
GO:0032782	bile acid secretion	5.302562e-7
GO:0003096	renal sodium ion transport	5.302562e-7
GO:0000279	M phase	8.650344e-7
GO:0048609	multicellular organismal reproductive process	8.697610e-7
GO:0006475	internal protein amino acid acetylation	9.644336e-7
GO:0045653	negative regulation of megakaryocyte differentiation	1.660420e-6
GO:0018393	internal peptidyl-lysine acetylation	1.726799e-6
GO:0006102	isocitrate metabolic process	1.867381e-6
GO:0006457	protein folding	1.953141e-6
GO:0018394	peptidyl-lysine acetylation	2.070776e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	2.273063e-6
GO:0007049	cell cycle	2.939300e-6
GO:0034622	cellular macromolecular complex assembly	4.009476e-6
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	4.058883e-6
GO:0061034	olfactory bulb mitral cell layer development	4.579546e-6
GO:0034621	cellular macromolecular complex subunit organization	4.701882e-6
GO:0034635	glutathione transport	4.813804e-6
GO:0006473	protein acetylation	6.277680e-6
GO:0014707	branchiomeric skeletal muscle development	6.396168e-6
GO:0006099	tricarboxylic acid cycle	6.992548e-6
GO:0051932	synaptic transmission, GABAergic	7.558182e-6
GO:0080164	regulation of nitric oxide metabolic process	7.558182e-6
GO:0035750	protein localization to myelin sheath abaxonal region	7.608743e-6
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	7.625732e-6
GO:0021993	initiation of neural tube closure	8.532907e-6
GO:0030202	heparin metabolic process	1.125864e-5
GO:0016139	glycoside catabolic process	1.325360e-5
GO:0006913	nucleocytoplasmic transport	1.425932e-5
GO:0021756	striatum development	1.890909e-5
GO:0006370	mRNA capping	1.901518e-5
GO:0015761	mannose transport	1.940622e-5
GO:0022403	cell cycle phase	1.947980e-5
GO:0046356	acetyl-CoA catabolic process	2.223233e-5
GO:0034976	response to endoplasmic reticulum stress	2.243576e-5
GO:0043967	histone H4 acetylation	2.289617e-5
GO:0046885	regulation of hormone biosynthetic process	2.423632e-5
GO:0046477	glycosylceramide catabolic process	2.437018e-5
GO:0016573	histone acetylation	2.463694e-5
GO:0045652	regulation of megakaryocyte differentiation	2.570170e-5
GO:0051169	nuclear transport	2.614074e-5
GO:0018205	peptidyl-lysine modification	2.781561e-5
GO:0009109	coenzyme catabolic process	3.026294e-5
GO:0046886	positive regulation of hormone biosynthetic process	3.132299e-5
GO:0021794	thalamus development	3.143422e-5
GO:0000819	sister chromatid segregation	3.259086e-5
GO:0021544	subpallium development	3.691065e-5
GO:0032859	activation of Ral GTPase activity	3.903331e-5
GO:0006482	protein demethylation	3.950268e-5
GO:0032467	positive regulation of cytokinesis	3.979522e-5
GO:0010155	regulation of proton transport	4.313380e-5
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	4.322069e-5
GO:0006507	GPI anchor release	4.322069e-5
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.594929e-5
GO:0071922	regulation of cohesin localization to chromatin	4.882689e-5
GO:0007052	mitotic spindle organization	5.698727e-5
GO:0000070	mitotic sister chromatid segregation	5.812573e-5
GO:0051302	regulation of cell division	5.818470e-5
GO:0006450	regulation of translational fidelity	6.579710e-5
GO:0046514	ceramide catabolic process	6.683265e-5
GO:0070988	demethylation	6.748025e-5
GO:0046466	membrane lipid catabolic process	8.340959e-5
GO:0007067	mitosis	8.354117e-5
GO:0010226	response to lithium ion	8.447152e-5
GO:0034587	piRNA metabolic process	8.627441e-5
GO:0051029	rRNA transport	9.165826e-5
GO:0048011	nerve growth factor receptor signaling pathway	9.343407e-5
GO:0032465	regulation of cytokinesis	1.020291e-4
GO:0000087	M phase of mitotic cell cycle	1.032116e-4
GO:0071844	cellular component assembly at cellular level	1.035271e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	1.040729e-4
GO:0051187	cofactor catabolic process	1.123139e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	1.143815e-4
GO:0006637	acyl-CoA metabolic process	1.264369e-4
GO:0006996	organelle organization	1.432622e-4
GO:0035852	horizontal cell localization	1.441831e-4
GO:0035849	nephric duct elongation	1.441831e-4
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	1.441831e-4
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.441831e-4
GO:0035847	uterine epithelium development	1.441831e-4
GO:0035846	oviduct epithelium development	1.441831e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.608255e-4
GO:0009452	RNA capping	1.627505e-4
GO:0021680	cerebellar Purkinje cell layer development	1.699409e-4
GO:0070383	DNA cytosine deamination	1.704213e-4
GO:0010529	negative regulation of transposition	1.704213e-4
GO:0030433	ER-associated protein catabolic process	1.761300e-4
GO:0071379	cellular response to prostaglandin stimulus	1.797325e-4
GO:0060264	regulation of respiratory burst involved in inflammatory response	1.925216e-4
GO:0021678	third ventricle development	1.949203e-4
GO:0044260	cellular macromolecule metabolic process	2.055305e-4
GO:0006304	DNA modification	2.090344e-4
GO:0060272	embryonic skeletal joint morphogenesis	2.173958e-4
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	2.259952e-4
GO:0010025	wax biosynthetic process	2.259952e-4
GO:0016236	macroautophagy	2.320680e-4
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	2.326917e-4
GO:0009229	thiamine diphosphate biosynthetic process	2.326917e-4
GO:0022402	cell cycle process	2.344777e-4
GO:0000045	autophagic vacuole assembly	2.547584e-4
GO:0030149	sphingolipid catabolic process	2.587439e-4
GO:0021592	fourth ventricle development	2.754200e-4
GO:0043501	skeletal muscle adaptation	2.796039e-4
GO:0021860	pyramidal neuron development	2.943284e-4
GO:0015816	glycine transport	2.996869e-4
GO:0016137	glycoside metabolic process	3.025753e-4
GO:0072498	embryonic skeletal joint development	3.098151e-4
GO:0032352	positive regulation of hormone metabolic process	3.433063e-4
GO:0043543	protein acylation	3.437908e-4
GO:0070293	renal absorption	3.471981e-4
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	3.550227e-4
GO:0021985	neurohypophysis development	3.572941e-4
GO:0051457	maintenance of protein location in nucleus	3.718602e-4
GO:0051168	nuclear export	3.764565e-4
GO:0031018	endocrine pancreas development	3.876331e-4
GO:0044267	cellular protein metabolic process	4.302253e-4
GO:0010725	regulation of primitive erythrocyte differentiation	4.459773e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	4.592180e-4
GO:0006732	coenzyme metabolic process	4.735190e-4
GO:0043968	histone H2A acetylation	4.838465e-4
GO:0019377	glycolipid catabolic process	5.268925e-4
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	5.292569e-4
GO:0035502	metanephric ureteric bud development	5.540580e-4
GO:0051568	histone H3-K4 methylation	5.655931e-4
GO:0006704	glucocorticoid biosynthetic process	5.782395e-4
GO:0016568	chromatin modification	5.802397e-4
GO:0048002	antigen processing and presentation of peptide antigen	6.233075e-4
GO:0009108	coenzyme biosynthetic process	6.397007e-4
GO:0019882	antigen processing and presentation	6.420888e-4
GO:0043524	negative regulation of neuron apoptosis	6.939872e-4
GO:0034694	response to prostaglandin stimulus	7.138285e-4
GO:0033143	regulation of steroid hormone receptor signaling pathway	7.176099e-4
GO:0007076	mitotic chromosome condensation	7.348699e-4
GO:0035928	rRNA import into mitochondrion	7.468223e-4
GO:0021979	hypothalamus cell differentiation	7.632562e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	7.693473e-4
GO:0016577	histone demethylation	7.804533e-4
GO:0031047	gene silencing by RNA	7.956941e-4
GO:0051001	negative regulation of nitric-oxide synthase activity	8.053145e-4
GO:0032594	protein transport within lipid bilayer	8.115436e-4
GO:0008206	bile acid metabolic process	8.215443e-4
GO:0048285	organelle fission	8.551661e-4
GO:0009060	aerobic respiration	9.111467e-4
GO:0006306	DNA methylation	9.448801e-4
GO:0051260	protein homooligomerization	9.449366e-4
GO:0034118	regulation of erythrocyte aggregation	9.657820e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	9.657820e-4
GO:0070474	positive regulation of uterine smooth muscle contraction	9.681931e-4
GO:0007126	meiosis	1.009987e-3
GO:0006270	DNA-dependent DNA replication initiation	1.057944e-3
GO:0051781	positive regulation of cell division	1.074447e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	1.088042e-3
GO:0007157	heterophilic cell-cell adhesion	1.096748e-3
GO:0007059	chromosome segregation	1.127804e-3
GO:0032350	regulation of hormone metabolic process	1.131157e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	1.148123e-3
GO:0006984	ER-nucleus signaling pathway	1.190577e-3
GO:0021702	cerebellar Purkinje cell differentiation	1.202314e-3
GO:0032715	negative regulation of interleukin-6 production	1.228248e-3
GO:0072259	metanephric interstitial cell development	1.228978e-3
GO:0072208	metanephric smooth muscle tissue development	1.228978e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	1.228978e-3
GO:0051775	response to redox state	1.228978e-3
GO:0072184	renal vesicle progenitor cell differentiation	1.228978e-3
GO:0072168	specification of anterior mesonephric tubule identity	1.228978e-3
GO:0072169	specification of posterior mesonephric tubule identity	1.228978e-3
GO:0045426	quinone cofactor biosynthetic process	1.277306e-3
GO:0042450	arginine biosynthetic process via ornithine	1.330835e-3
GO:0019676	ammonia assimilation cycle	1.330835e-3
GO:0051983	regulation of chromosome segregation	1.387768e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	1.440272e-3
GO:0043170	macromolecule metabolic process	1.531832e-3
GO:0031999	negative regulation of fatty acid beta-oxidation	1.548241e-3
GO:0001705	ectoderm formation	1.548241e-3
GO:0051403	stress-activated MAPK cascade	1.555106e-3
GO:0046825	regulation of protein export from nucleus	1.575262e-3
GO:0042375	quinone cofactor metabolic process	1.588489e-3
GO:0043011	myeloid dendritic cell differentiation	1.635104e-3
GO:0051321	meiotic cell cycle	1.698545e-3
GO:0002329	pre-B cell differentiation	1.761743e-3
GO:0014888	striated muscle adaptation	1.825915e-3
GO:0009972	cytidine deamination	1.852157e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.852157e-3
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	1.908560e-3
GO:0051382	kinetochore assembly	1.908560e-3
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	1.908560e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	1.944961e-3
GO:0007549	dosage compensation	1.944961e-3
GO:0032415	regulation of sodium:hydrogen antiporter activity	1.995188e-3
GO:0006003	fructose 2,6-bisphosphate metabolic process	1.998962e-3
GO:0035904	aorta development	2.045338e-3
GO:0045494	photoreceptor cell maintenance	2.045559e-3
GO:0016570	histone modification	2.070672e-3
GO:0021695	cerebellar cortex development	2.155255e-3
GO:0070189	kynurenine metabolic process	2.223345e-3
GO:0050658	RNA transport	2.284658e-3
GO:0071322	cellular response to carbohydrate stimulus	2.345813e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	2.365939e-3
GO:0046323	glucose import	2.365939e-3
GO:0030033	microvillus assembly	2.365939e-3
GO:0042159	lipoprotein catabolic process	2.422122e-3
GO:0014842	regulation of satellite cell proliferation	2.479090e-3
GO:0007080	mitotic metaphase plate congression	2.496203e-3
GO:0042362	fat-soluble vitamin biosynthetic process	2.600219e-3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.659135e-3
GO:0006772	thiamine metabolic process	2.661858e-3
GO:0072385	minus-end-directed organelle transport along microtubule	2.661858e-3
GO:0035087	siRNA loading onto RISC involved in RNA interference	2.750071e-3
GO:0033315	meiotic cell cycle DNA replication checkpoint	2.750071e-3
GO:0010032	meiotic chromosome condensation	2.750071e-3
GO:0001712	ectodermal cell fate commitment	2.750071e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.787528e-3
GO:0007127	meiosis I	2.842011e-3
GO:0000278	mitotic cell cycle	2.876767e-3
GO:0097039	protein linear polyubiquitination	2.877979e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.913992e-3
GO:0050810	regulation of steroid biosynthetic process	3.031177e-3
GO:0021517	ventral spinal cord development	3.060425e-3
GO:0035434	copper ion transmembrane transport	3.081669e-3
GO:0014002	astrocyte development	3.091157e-3
GO:0010744	positive regulation of macrophage derived foam cell differentiation	3.103295e-3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	3.113513e-3
GO:0044337	canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis	3.163884e-3
GO:0048143	astrocyte activation	3.264346e-3
GO:0048242	epinephrine secretion	3.275452e-3
GO:0018106	peptidyl-histidine phosphorylation	3.275452e-3
GO:0006403	RNA localization	3.287673e-3
GO:0016569	covalent chromatin modification	3.307625e-3
GO:0015698	inorganic anion transport	3.397487e-3
GO:0033552	response to vitamin B3	3.469608e-3
GO:0046135	pyrimidine nucleoside catabolic process	3.469945e-3
GO:0006084	acetyl-CoA metabolic process	3.476451e-3
GO:0032507	maintenance of protein location in cell	3.510773e-3
GO:0070076	histone lysine demethylation	3.546425e-3
GO:0018202	peptidyl-histidine modification	3.671003e-3
GO:0051496	positive regulation of stress fiber assembly	3.732589e-3
GO:0031573	intra-S DNA damage checkpoint	3.737447e-3
GO:0071333	cellular response to glucose stimulus	3.765156e-3
GO:0043149	stress fiber assembly	3.786833e-3
GO:0048840	otolith development	3.800896e-3
GO:0045454	cell redox homeostasis	3.913097e-3
GO:0030070	insulin processing	3.975014e-3
GO:0060840	artery development	4.001118e-3
GO:0018193	peptidyl-amino acid modification	4.122650e-3
GO:0072194	kidney smooth muscle tissue development	4.147028e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	4.160454e-3
GO:0032910	regulation of transforming growth factor beta3 production	4.248199e-3
GO:0003357	noradrenergic neuron differentiation	4.307718e-3
GO:0051301	cell division	4.366418e-3
GO:0045006	DNA deamination	4.401773e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.401773e-3
GO:0021782	glial cell development	4.716326e-3
GO:0007229	integrin-mediated signaling pathway	4.776723e-3
GO:0061113	pancreas morphogenesis	4.810976e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	4.810976e-3
GO:0010631	epithelial cell migration	4.849465e-3
GO:0007525	somatic muscle development	4.868573e-3
GO:0006465	signal peptide processing	4.868573e-3
GO:0006089	lactate metabolic process	4.868573e-3
GO:0033625	positive regulation of integrin activation	4.917329e-3
GO:0001732	formation of translation initiation complex	4.917329e-3
GO:0032119	sequestering of zinc ion	4.917329e-3
GO:0061370	testosterone biosynthetic process	4.924482e-3
GO:0051383	kinetochore organization	4.924482e-3
GO:0001881	receptor recycling	4.924482e-3
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	4.947841e-3
GO:0007174	epidermal growth factor catabolic process	4.947841e-3
GO:0010884	positive regulation of lipid storage	5.012414e-3
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	5.071642e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	5.071642e-3
GO:0048680	positive regulation of axon regeneration	5.420818e-3
GO:0043933	macromolecular complex subunit organization	5.457667e-3
GO:0006144	purine base metabolic process	5.527057e-3
GO:0071285	cellular response to lithium ion	5.527057e-3
GO:0030002	cellular anion homeostasis	5.671551e-3
GO:0046827	positive regulation of protein export from nucleus	5.788672e-3
GO:0043508	negative regulation of JUN kinase activity	5.788672e-3
GO:0035909	aorta morphogenesis	5.900116e-3
GO:0030163	protein catabolic process	5.902112e-3
GO:0031647	regulation of protein stability	5.948890e-3
GO:0071248	cellular response to metal ion	5.963628e-3
GO:0022618	ribonucleoprotein complex assembly	6.007002e-3
GO:0006268	DNA unwinding involved in replication	6.020244e-3
GO:0021997	neural plate axis specification	6.024121e-3
GO:0006419	alanyl-tRNA aminoacylation	6.024121e-3
GO:0048708	astrocyte differentiation	6.040995e-3
GO:0060174	limb bud formation	6.040995e-3
GO:0016584	nucleosome positioning	6.105961e-3
GO:0040029	regulation of gene expression, epigenetic	6.180015e-3
GO:0048844	artery morphogenesis	6.366424e-3
GO:0048679	regulation of axon regeneration	6.397931e-3
GO:0035307	positive regulation of protein dephosphorylation	6.397931e-3
GO:0001975	response to amphetamine	6.475268e-3
GO:0006700	C21-steroid hormone biosynthetic process	6.486774e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	6.544467e-3
GO:0044090	positive regulation of vacuole organization	6.614458e-3
GO:0009234	menaquinone biosynthetic process	6.614458e-3
GO:0000379	tRNA-type intron splice site recognition and cleavage	6.614458e-3
GO:0007033	vacuole organization	6.660012e-3
GO:0051186	cofactor metabolic process	6.661191e-3
GO:0097115	neurexin clustering	6.669409e-3
GO:0007021	tubulin complex assembly	6.669409e-3
GO:0007281	germ cell development	6.720669e-3
GO:0043117	positive regulation of vascular permeability	6.765047e-3
GO:0021750	vestibular nucleus development	6.765047e-3
GO:0021679	cerebellar molecular layer development	6.765047e-3
GO:0021590	cerebellum maturation	6.765047e-3
GO:0071634	regulation of transforming growth factor beta production	6.829738e-3
GO:0006730	one-carbon metabolic process	6.868460e-3
GO:0070830	tight junction assembly	6.882862e-3
GO:0035306	positive regulation of dephosphorylation	6.882862e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	6.887339e-3
GO:0035910	ascending aorta morphogenesis	6.887339e-3
GO:0032769	negative regulation of monooxygenase activity	6.887339e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	6.887339e-3
GO:0006261	DNA-dependent DNA replication	6.936141e-3
GO:0006260	DNA replication	7.185353e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	7.285494e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	7.285494e-3
GO:0046668	regulation of retinal cell programmed cell death	7.370895e-3
GO:0071826	ribonucleoprotein complex subunit organization	7.413521e-3
GO:0060252	positive regulation of glial cell proliferation	7.542570e-3
GO:0010388	cullin deneddylation	7.542570e-3
GO:0006596	polyamine biosynthetic process	7.542570e-3
GO:0044257	cellular protein catabolic process	7.848348e-3
GO:0046039	GTP metabolic process	7.880202e-3
GO:0050821	protein stabilization	7.922982e-3
GO:0045070	positive regulation of viral genome replication	7.939839e-3
GO:0018960	4-nitrophenol metabolic process	7.961847e-3
GO:0000244	assembly of spliceosomal tri-snRNP	7.961847e-3
GO:0021670	lateral ventricle development	8.233510e-3
GO:0035519	protein K29-linked ubiquitination	8.271890e-3
GO:0045185	maintenance of protein location	8.346247e-3
GO:0002042	cell migration involved in sprouting angiogenesis	8.398856e-3
GO:0032873	negative regulation of stress-activated MAPK cascade	8.523099e-3
GO:0019538	protein metabolic process	8.618910e-3
GO:0033554	cellular response to stress	8.628932e-3
GO:0043526	neuroprotection	8.665116e-3
GO:0044272	sulfur compound biosynthetic process	8.713877e-3
GO:0006591	ornithine metabolic process	8.719807e-3
GO:0033036	macromolecule localization	8.821675e-3
GO:0060405	regulation of penile erection	8.941287e-3
GO:0070534	protein K63-linked ubiquitination	9.199526e-3
GO:0006405	RNA export from nucleus	9.269206e-3
GO:0046907	intracellular transport	9.305720e-3
GO:0030522	intracellular receptor mediated signaling pathway	9.309027e-3
GO:0046854	phosphatidylinositol phosphorylation	9.310939e-3
GO:0001678	cellular glucose homeostasis	9.359947e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	9.469165e-3
GO:0044314	protein K27-linked ubiquitination	9.537013e-3
GO:0071228	cellular response to tumor cell	9.537013e-3
GO:0043500	muscle adaptation	9.641180e-3
GO:0018208	peptidyl-proline modification	9.689268e-3
GO:0021903	rostrocaudal neural tube patterning	9.857122e-3
GO:0001569	patterning of blood vessels	9.895504e-3
GO:0043154	negative regulation of caspase activity	9.921593e-3
GO:0035270	endocrine system development	1.003637e-2
GO:0034504	protein localization to nucleus	1.011737e-2
GO:0046014	negative regulation of T cell homeostatic proliferation	1.037393e-2
GO:0042103	positive regulation of T cell homeostatic proliferation	1.037393e-2
GO:0046836	glycolipid transport	1.037393e-2
GO:0090292	nuclear matrix anchoring at nuclear membrane	1.037393e-2
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.037393e-2
GO:0035562	negative regulation of chromatin binding	1.037393e-2
GO:0032600	chemokine receptor transport out of membrane raft	1.037393e-2
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.037393e-2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.037393e-2
GO:0032913	negative regulation of transforming growth factor beta3 production	1.037393e-2
GO:0034107	negative regulation of erythrocyte clearance	1.037393e-2
GO:0034119	negative regulation of erythrocyte aggregation	1.037393e-2
GO:0010886	positive regulation of cholesterol storage	1.037634e-2
GO:0050883	musculoskeletal movement, spinal reflex action	1.041002e-2
GO:0045634	regulation of melanocyte differentiation	1.062059e-2
GO:0032508	DNA duplex unwinding	1.062059e-2
GO:0071383	cellular response to steroid hormone stimulus	1.074615e-2
GO:2000543	positive regulation of gastrulation	1.075245e-2
GO:0021884	forebrain neuron development	1.084731e-2
GO:0046887	positive regulation of hormone secretion	1.101749e-2
GO:0046532	regulation of photoreceptor cell differentiation	1.105050e-2
GO:0021515	cell differentiation in spinal cord	1.120187e-2
GO:0044237	cellular metabolic process	1.120331e-2
GO:0019674	NAD metabolic process	1.152239e-2
GO:0070544	histone H3-K36 demethylation	1.152271e-2
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.156256e-2
GO:0006914	autophagy	1.170579e-2
GO:0042384	cilium assembly	1.173755e-2
GO:0072141	renal interstitial cell development	1.188534e-2
GO:0001672	regulation of chromatin assembly or disassembly	1.188534e-2
GO:0048496	maintenance of organ identity	1.188534e-2
GO:0021527	spinal cord association neuron differentiation	1.190499e-2
GO:0051028	mRNA transport	1.196084e-2
GO:0043666	regulation of phosphoprotein phosphatase activity	1.199308e-2
GO:0000413	protein peptidyl-prolyl isomerization	1.208757e-2
GO:0034383	low-density lipoprotein particle clearance	1.211277e-2
GO:0048133	male germ-line stem cell division	1.214980e-2
GO:0035441	cell migration involved in vasculogenesis	1.214980e-2
GO:0032392	DNA geometric change	1.248153e-2
GO:0071635	negative regulation of transforming growth factor beta production	1.248153e-2
GO:0042446	hormone biosynthetic process	1.254718e-2
GO:0031017	exocrine pancreas development	1.267266e-2
GO:0050796	regulation of insulin secretion	1.269021e-2
GO:0006611	protein export from nucleus	1.273193e-2
GO:0042770	signal transduction in response to DNA damage	1.273939e-2
GO:0030490	maturation of SSU-rRNA	1.277668e-2
GO:0006857	oligopeptide transport	1.277668e-2
GO:0071242	cellular response to ammonium ion	1.279260e-2
GO:0042373	vitamin K metabolic process	1.279260e-2
GO:0045875	negative regulation of sister chromatid cohesion	1.279260e-2
GO:0045345	positive regulation of MHC class I biosynthetic process	1.279260e-2
GO:0002328	pro-B cell differentiation	1.280886e-2
GO:0070060	'de novo' actin filament nucleation	1.309760e-2
GO:0008295	spermidine biosynthetic process	1.309760e-2
GO:0030240	skeletal muscle thin filament assembly	1.312204e-2
GO:0090030	regulation of steroid hormone biosynthetic process	1.314179e-2
GO:0034968	histone lysine methylation	1.315752e-2
GO:0051225	spindle assembly	1.319061e-2
GO:0046883	regulation of hormone secretion	1.324001e-2
GO:0010927	cellular component assembly involved in morphogenesis	1.333172e-2
GO:0045930	negative regulation of mitotic cell cycle	1.343760e-2
GO:0006024	glycosaminoglycan biosynthetic process	1.349115e-2
GO:0060563	neuroepithelial cell differentiation	1.350012e-2
GO:0035372	protein localization to microtubule	1.350178e-2
GO:0051238	sequestering of metal ion	1.350178e-2
GO:0031394	positive regulation of prostaglandin biosynthetic process	1.350178e-2
GO:0010724	regulation of definitive erythrocyte differentiation	1.350178e-2
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.350178e-2
GO:0008356	asymmetric cell division	1.350178e-2
GO:0071841	cellular component organization or biogenesis at cellular level	1.360783e-2
GO:0060022	hard palate development	1.373533e-2
GO:0015804	neutral amino acid transport	1.401682e-2
GO:0021905	forebrain-midbrain boundary formation	1.416542e-2
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	1.416542e-2
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	1.416542e-2
GO:0003322	pancreatic A cell development	1.416542e-2
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	1.417275e-2
GO:0006366	transcription from RNA polymerase II promoter	1.497776e-2
GO:0035907	dorsal aorta development	1.498670e-2
GO:0060075	regulation of resting membrane potential	1.498670e-2
GO:0016458	gene silencing	1.505947e-2
GO:0031016	pancreas development	1.507188e-2
GO:0060112	generation of ovulation cycle rhythm	1.536964e-2
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	1.536964e-2
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.536964e-2
GO:0045404	positive regulation of interleukin-4 biosynthetic process	1.540673e-2
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.540673e-2
GO:0051235	maintenance of location	1.548024e-2
GO:0002575	basophil chemotaxis	1.554287e-2
GO:0045333	cellular respiration	1.564373e-2
GO:0007063	regulation of sister chromatid cohesion	1.571903e-2
GO:0006677	glycosylceramide metabolic process	1.583383e-2
GO:0007051	spindle organization	1.601360e-2
GO:0071529	cementum mineralization	1.639371e-2
GO:0046591	embryonic leg joint morphogenesis	1.639371e-2
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.639371e-2
GO:0031282	regulation of guanylate cyclase activity	1.639371e-2
GO:0000041	transition metal ion transport	1.639566e-2
GO:0006354	transcription elongation, DNA-dependent	1.647178e-2
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.653549e-2
GO:0006406	mRNA export from nucleus	1.659886e-2
GO:0003065	positive regulation of heart rate by epinephrine	1.660556e-2
GO:0006103	2-oxoglutarate metabolic process	1.661221e-2
GO:0045022	early endosome to late endosome transport	1.668546e-2
GO:0051651	maintenance of location in cell	1.670975e-2
GO:0006821	chloride transport	1.708968e-2
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	1.718271e-2
GO:0015879	carnitine transport	1.718271e-2
GO:0021578	hindbrain maturation	1.718271e-2
GO:0015680	intracellular copper ion transport	1.731501e-2
GO:0044088	regulation of vacuole organization	1.731501e-2
GO:0000053	argininosuccinate metabolic process	1.731501e-2
GO:0046329	negative regulation of JNK cascade	1.747307e-2
GO:0051354	negative regulation of oxidoreductase activity	1.776767e-2
GO:0007032	endosome organization	1.776962e-2
GO:0072668	tubulin complex biogenesis	1.784061e-2
GO:0006568	tryptophan metabolic process	1.784061e-2
GO:0065003	macromolecular complex assembly	1.784134e-2