Novel motif:103

name:	motif103_CGGCTAWWT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0090304	nucleic acid metabolic process	2.543609e-16
GO:0032774	RNA biosynthetic process	1.565633e-15
GO:0006351	transcription, DNA-dependent	5.202064e-15
GO:0016070	RNA metabolic process	2.252945e-13
GO:2000119	negative regulation of sodium-dependent phosphate transport	7.723673e-13
GO:0010467	gene expression	1.638894e-12
GO:0034645	cellular macromolecule biosynthetic process	9.398832e-12
GO:0009059	macromolecule biosynthetic process	5.432259e-11
GO:0006139	nucleobase-containing compound metabolic process	5.283164e-10
GO:0034641	cellular nitrogen compound metabolic process	6.300595e-10
GO:0010468	regulation of gene expression	6.815122e-10
GO:2000112	regulation of cellular macromolecule biosynthetic process	8.533025e-10
GO:0006807	nitrogen compound metabolic process	9.220636e-10
GO:0006355	regulation of transcription, DNA-dependent	2.193709e-9
GO:0051252	regulation of RNA metabolic process	2.782201e-9
GO:0071333	cellular response to glucose stimulus	7.696120e-9
GO:0001678	cellular glucose homeostasis	1.245457e-8
GO:0010556	regulation of macromolecule biosynthetic process	1.529219e-8
GO:0010628	positive regulation of gene expression	2.664246e-8
GO:0071322	cellular response to carbohydrate stimulus	2.767967e-8
GO:0045893	positive regulation of transcription, DNA-dependent	3.023475e-8
GO:0044249	cellular biosynthetic process	5.302293e-8
GO:0072132	mesenchyme morphogenesis	5.316031e-8
GO:0009058	biosynthetic process	6.514579e-8
GO:0060056	mammary gland involution	7.596701e-8
GO:0010966	regulation of phosphate transport	1.770332e-7
GO:0031345	negative regulation of cell projection organization	2.457732e-7
GO:0060395	SMAD protein signal transduction	2.487253e-7
GO:0051254	positive regulation of RNA metabolic process	2.551172e-7
GO:0006695	cholesterol biosynthetic process	3.464066e-7
GO:0072234	metanephric nephron tubule development	4.223664e-7
GO:0072282	metanephric nephron tubule morphogenesis	5.321325e-7
GO:0072170	metanephric tubule development	6.060445e-7
GO:0045065	cytotoxic T cell differentiation	6.534067e-7
GO:0006600	creatine metabolic process	7.641803e-7
GO:0001945	lymph vessel development	1.223743e-6
GO:0051290	protein heterotetramerization	1.428216e-6
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.478580e-6
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	2.101991e-6
GO:0031326	regulation of cellular biosynthetic process	2.186580e-6
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	2.533595e-6
GO:0045717	negative regulation of fatty acid biosynthetic process	2.820389e-6
GO:0000082	G1/S transition of mitotic cell cycle	3.251446e-6
GO:0090086	negative regulation of protein deubiquitination	3.380699e-6
GO:0072148	epithelial cell fate commitment	3.486956e-6
GO:0072207	metanephric epithelium development	3.654303e-6
GO:0046314	phosphocreatine biosynthetic process	3.718385e-6
GO:0003188	heart valve formation	3.944262e-6
GO:0009889	regulation of biosynthetic process	3.986636e-6
GO:0045444	fat cell differentiation	4.361806e-6
GO:0060088	auditory receptor cell stereocilium organization	4.516835e-6
GO:0050771	negative regulation of axonogenesis	4.716349e-6
GO:0018027	peptidyl-lysine dimethylation	4.919513e-6
GO:0060376	positive regulation of mast cell differentiation	6.287844e-6
GO:0044260	cellular macromolecule metabolic process	6.486206e-6
GO:0010983	positive regulation of high-density lipoprotein particle clearance	6.519767e-6
GO:0045750	positive regulation of S phase of mitotic cell cycle	6.547568e-6
GO:0060255	regulation of macromolecule metabolic process	6.882493e-6
GO:0022601	menstrual cycle phase	8.011988e-6
GO:0060375	regulation of mast cell differentiation	9.032706e-6
GO:0051329	interphase of mitotic cell cycle	1.045724e-5
GO:0035048	splicing factor protein import into nucleus	1.051835e-5
GO:0002093	auditory receptor cell morphogenesis	1.054496e-5
GO:0003197	endocardial cushion development	1.064565e-5
GO:0090085	regulation of protein deubiquitination	1.134999e-5
GO:0043461	proton-transporting ATP synthase complex assembly	1.134999e-5
GO:0002092	positive regulation of receptor internalization	1.281970e-5
GO:0045606	positive regulation of epidermal cell differentiation	1.333851e-5
GO:0071569	protein ufmylation	1.415578e-5
GO:0035871	protein K11-linked deubiquitination	1.629089e-5
GO:0016126	sterol biosynthetic process	1.876768e-5
GO:0051325	interphase	1.972170e-5
GO:0043267	negative regulation of potassium ion transport	2.089875e-5
GO:0006281	DNA repair	2.173431e-5
GO:0006302	double-strand break repair	2.465021e-5
GO:0045922	negative regulation of fatty acid metabolic process	2.654129e-5
GO:0055062	phosphate ion homeostasis	2.704859e-5
GO:0021553	olfactory nerve development	2.868095e-5
GO:0045446	endothelial cell differentiation	3.148241e-5
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.188767e-5
GO:0006413	translational initiation	3.189132e-5
GO:0048562	embryonic organ morphogenesis	3.840818e-5
GO:0042396	phosphagen biosynthetic process	3.865052e-5
GO:0001839	neural plate morphogenesis	3.899423e-5
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3.904720e-5
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.057214e-5
GO:0030177	positive regulation of Wnt receptor signaling pathway	4.073233e-5
GO:0008333	endosome to lysosome transport	4.144164e-5
GO:0006974	response to DNA damage stimulus	4.192120e-5
GO:0006549	isoleucine metabolic process	4.413774e-5
GO:0060122	inner ear receptor stereocilium organization	4.515228e-5
GO:0090074	negative regulation of protein homodimerization activity	4.652820e-5
GO:0000578	embryonic axis specification	4.883772e-5
GO:0010986	positive regulation of lipoprotein particle clearance	5.007230e-5
GO:0016055	Wnt receptor signaling pathway	5.383687e-5
GO:0072289	metanephric nephron tubule formation	5.467385e-5
GO:0007548	sex differentiation	5.488526e-5
GO:0042471	ear morphogenesis	5.559508e-5
GO:0042552	myelination	5.757440e-5
GO:0060839	endothelial cell fate commitment	6.217524e-5
GO:0006357	regulation of transcription from RNA polymerase II promoter	6.313348e-5
GO:0021933	radial glia guided migration of cerebellar granule cell	6.377746e-5
GO:0048213	Golgi vesicle prefusion complex stabilization	6.377746e-5
GO:0015853	adenine transport	6.618847e-5
GO:0030967	ER-nuclear sterol response pathway	6.710095e-5
GO:0016575	histone deacetylation	6.899180e-5
GO:0001756	somitogenesis	7.021123e-5
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	7.437150e-5
GO:0014063	negative regulation of serotonin secretion	7.493166e-5
GO:0046479	glycosphingolipid catabolic process	7.614996e-5
GO:0030308	negative regulation of cell growth	7.778618e-5
GO:0051084	'de novo' posttranslational protein folding	7.926078e-5
GO:0051173	positive regulation of nitrogen compound metabolic process	8.099228e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	8.153594e-5
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	8.176695e-5
GO:0046415	urate metabolic process	8.218557e-5
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	8.312868e-5
GO:0051171	regulation of nitrogen compound metabolic process	8.986242e-5
GO:0060737	prostate gland morphogenetic growth	9.366014e-5
GO:0010557	positive regulation of macromolecule biosynthetic process	9.692650e-5
GO:0042472	inner ear morphogenesis	9.717840e-5
GO:0048343	paraxial mesodermal cell fate commitment	1.040183e-4
GO:0072189	ureter development	1.146337e-4
GO:0050768	negative regulation of neurogenesis	1.179143e-4
GO:0048568	embryonic organ development	1.234684e-4
GO:0090324	negative regulation of oxidative phosphorylation	1.237353e-4
GO:0010255	glucose mediated signaling pathway	1.237353e-4
GO:0007034	vacuolar transport	1.241322e-4
GO:0010991	negative regulation of SMAD protein complex assembly	1.249849e-4
GO:0019915	lipid storage	1.273983e-4
GO:0061136	regulation of proteasomal protein catabolic process	1.320457e-4
GO:0051320	S phase	1.388922e-4
GO:0003203	endocardial cushion morphogenesis	1.395264e-4
GO:0007041	lysosomal transport	1.473288e-4
GO:0071557	histone H3-K27 demethylation	1.476846e-4
GO:0035574	histone H4-K20 demethylation	1.476846e-4
GO:0018026	peptidyl-lysine monomethylation	1.483882e-4
GO:0001840	neural plate development	1.560335e-4
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.580404e-4
GO:0070682	proteasome regulatory particle assembly	1.641482e-4
GO:0021545	cranial nerve development	1.707164e-4
GO:0003158	endothelium development	1.753982e-4
GO:0009636	response to toxin	1.764393e-4
GO:0001514	selenocysteine incorporation	1.800731e-4
GO:0048846	axon extension involved in axon guidance	1.825390e-4
GO:0001656	metanephros development	1.896262e-4
GO:0030111	regulation of Wnt receptor signaling pathway	1.922722e-4
GO:0000084	S phase of mitotic cell cycle	1.924714e-4
GO:0007352	zygotic specification of dorsal/ventral axis	1.956609e-4
GO:0071479	cellular response to ionizing radiation	1.971748e-4
GO:0060485	mesenchyme development	2.037880e-4
GO:0006325	chromatin organization	2.062252e-4
GO:0031323	regulation of cellular metabolic process	2.063996e-4
GO:0007213	muscarinic acetylcholine receptor signaling pathway	2.089028e-4
GO:0003214	cardiac left ventricle morphogenesis	2.125203e-4
GO:0000185	activation of MAPKKK activity	2.125203e-4
GO:0030903	notochord development	2.148053e-4
GO:0008299	isoprenoid biosynthetic process	2.196163e-4
GO:0010950	positive regulation of endopeptidase activity	2.253283e-4
GO:0007090	regulation of S phase of mitotic cell cycle	2.435287e-4
GO:0003338	metanephros morphogenesis	2.460316e-4
GO:0031129	inductive cell-cell signaling	2.467044e-4
GO:0072273	metanephric nephron morphogenesis	2.528945e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	2.549045e-4
GO:0035622	intrahepatic bile duct development	2.619426e-4
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	2.619426e-4
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	2.619426e-4
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	2.619426e-4
GO:0003415	chondrocyte hypertrophy	2.619426e-4
GO:0014034	neural crest cell fate commitment	2.619426e-4
GO:0019100	male germ-line sex determination	2.619426e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	2.716850e-4
GO:0003002	regionalization	2.788454e-4
GO:0006476	protein deacetylation	2.803325e-4
GO:0006458	'de novo' protein folding	2.851310e-4
GO:0035282	segmentation	2.896595e-4
GO:0006333	chromatin assembly or disassembly	2.917232e-4
GO:0048333	mesodermal cell differentiation	3.061385e-4
GO:0051253	negative regulation of RNA metabolic process	3.066800e-4
GO:0000724	double-strand break repair via homologous recombination	3.067192e-4
GO:0008366	axon ensheathment	3.069443e-4
GO:0010756	positive regulation of plasminogen activation	3.175995e-4
GO:0006573	valine metabolic process	3.193779e-4
GO:0045926	negative regulation of growth	3.288010e-4
GO:0032825	positive regulation of natural killer cell differentiation	3.407706e-4
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	3.428482e-4
GO:0002082	regulation of oxidative phosphorylation	3.493497e-4
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	3.493497e-4
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	3.493497e-4
GO:0032200	telomere organization	3.584927e-4
GO:0035601	protein deacylation	3.597217e-4
GO:0030238	male sex determination	3.702633e-4
GO:0000725	recombinational repair	3.703808e-4
GO:0045665	negative regulation of neuron differentiation	3.798365e-4
GO:0060135	maternal process involved in female pregnancy	4.005691e-4
GO:0071922	regulation of cohesin localization to chromatin	4.034441e-4
GO:0060117	auditory receptor cell development	4.108855e-4
GO:0033598	mammary gland epithelial cell proliferation	4.200984e-4
GO:0070668	positive regulation of mast cell proliferation	4.226372e-4
GO:0044070	regulation of anion transport	4.259142e-4
GO:0030719	P granule organization	4.261417e-4
GO:0006259	DNA metabolic process	4.366033e-4
GO:0050686	negative regulation of mRNA processing	4.759424e-4
GO:0035459	cargo loading into vesicle	4.785746e-4
GO:0060644	mammary gland epithelial cell differentiation	4.827176e-4
GO:0060847	endothelial cell fate specification	5.017836e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	5.131196e-4
GO:0031120	snRNA pseudouridine synthesis	5.326043e-4
GO:0060286	flagellar cell motility	5.326043e-4
GO:0016142	O-glycoside catabolic process	5.326043e-4
GO:0006037	cell wall chitin metabolic process	5.326043e-4
GO:0008595	anterior/posterior axis specification, embryo	5.683610e-4
GO:0043266	regulation of potassium ion transport	5.779852e-4
GO:0000086	G2/M transition of mitotic cell cycle	6.048859e-4
GO:0060221	retinal rod cell differentiation	6.335076e-4
GO:0048839	inner ear development	6.342562e-4
GO:0045299	otolith mineralization	6.346248e-4
GO:0045137	development of primary sexual characteristics	6.608236e-4
GO:0080090	regulation of primary metabolic process	6.775667e-4
GO:0009956	radial pattern formation	6.831128e-4
GO:0051276	chromosome organization	6.971056e-4
GO:0060014	granulosa cell differentiation	7.110217e-4
GO:0007168	receptor guanylyl cyclase signaling pathway	7.139157e-4
GO:0015680	intracellular copper ion transport	7.241863e-4
GO:0030178	negative regulation of Wnt receptor signaling pathway	7.284367e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	7.406417e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	7.559151e-4
GO:0010044	response to aluminum ion	7.560445e-4
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	7.573360e-4
GO:0045885	positive regulation of survival gene product expression	7.606814e-4
GO:0001661	conditioned taste aversion	7.711682e-4
GO:0060764	cell-cell signaling involved in mammary gland development	7.751104e-4
GO:0033577	protein glycosylation in endoplasmic reticulum	7.751104e-4
GO:0009098	leucine biosynthetic process	7.751104e-4
GO:0006550	isoleucine catabolic process	7.751104e-4
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	7.772627e-4
GO:0046544	development of secondary male sexual characteristics	7.772627e-4
GO:0072034	renal vesicle induction	8.352616e-4
GO:0021707	cerebellar granule cell differentiation	8.437184e-4
GO:0043170	macromolecule metabolic process	8.446825e-4
GO:0060446	branching involved in open tracheal system development	8.973633e-4
GO:0090131	mesenchyme migration	8.973633e-4
GO:0060461	right lung morphogenesis	8.973633e-4
GO:0014822	detection of wounding	8.973633e-4
GO:0048371	lateral mesodermal cell differentiation	8.973633e-4
GO:0048613	embryonic ectodermal digestive tract morphogenesis	8.973633e-4
GO:0007350	blastoderm segmentation	8.981467e-4
GO:0010923	negative regulation of phosphatase activity	9.156435e-4
GO:0021524	visceral motor neuron differentiation	9.224035e-4
GO:0006362	transcription elongation from RNA polymerase I promoter	9.501353e-4
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	9.753892e-4
GO:0033119	negative regulation of RNA splicing	9.770481e-4
GO:0061364	apoptosis involved in luteolysis	9.811300e-4
GO:0061053	somite development	9.829762e-4
GO:0018993	somatic sex determination	9.991666e-4
GO:0048370	lateral mesoderm formation	9.991666e-4
GO:0043271	negative regulation of ion transport	9.995064e-4
GO:0010721	negative regulation of cell development	1.003178e-3
GO:0008406	gonad development	1.017140e-3
GO:0000723	telomere maintenance	1.040908e-3
GO:0043583	ear development	1.054172e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.080100e-3
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	1.086301e-3
GO:0043534	blood vessel endothelial cell migration	1.091662e-3
GO:0042593	glucose homeostasis	1.099919e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.128028e-3
GO:0048936	peripheral nervous system neuron axonogenesis	1.155345e-3
GO:0006313	transposition, DNA-mediated	1.155345e-3
GO:0031327	negative regulation of cellular biosynthetic process	1.182212e-3
GO:0051457	maintenance of protein location in nucleus	1.192653e-3
GO:0045862	positive regulation of proteolysis	1.195284e-3
GO:0019377	glycolipid catabolic process	1.212382e-3
GO:0002456	T cell mediated immunity	1.212382e-3
GO:0016139	glycoside catabolic process	1.223290e-3
GO:0033205	cell cycle cytokinesis	1.263219e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	1.269012e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.288520e-3
GO:0072009	nephron epithelium development	1.292247e-3
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.301266e-3
GO:0072073	kidney epithelium development	1.328294e-3
GO:0060745	mammary gland branching involved in pregnancy	1.338755e-3
GO:0070071	proton-transporting two-sector ATPase complex assembly	1.354480e-3
GO:0006368	transcription elongation from RNA polymerase II promoter	1.364353e-3
GO:0007072	positive regulation of transcription on exit from mitosis	1.413443e-3
GO:0006747	FAD biosynthetic process	1.413443e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.430812e-3
GO:0032916	positive regulation of transforming growth factor beta3 production	1.456475e-3
GO:0001675	acrosome assembly	1.456475e-3
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	1.491230e-3
GO:0045892	negative regulation of transcription, DNA-dependent	1.507242e-3
GO:0055081	anion homeostasis	1.510383e-3
GO:0060042	retina morphogenesis in camera-type eye	1.526295e-3
GO:0042703	menstruation	1.530254e-3
GO:0019101	female somatic sex determination	1.530254e-3
GO:0009057	macromolecule catabolic process	1.533646e-3
GO:0072078	nephron tubule morphogenesis	1.544360e-3
GO:0042491	auditory receptor cell differentiation	1.552104e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.562187e-3
GO:0048339	paraxial mesoderm development	1.647452e-3
GO:0007538	primary sex determination	1.651304e-3
GO:0031497	chromatin assembly	1.664929e-3
GO:0018022	peptidyl-lysine methylation	1.698770e-3
GO:0071504	cellular response to heparin	1.698770e-3
GO:0030514	negative regulation of BMP signaling pathway	1.747036e-3
GO:0060749	mammary gland alveolus development	1.779590e-3
GO:0006334	nucleosome assembly	1.793778e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.813056e-3
GO:0043249	erythrocyte maturation	1.816163e-3
GO:0006744	ubiquinone biosynthetic process	1.816163e-3
GO:0019530	taurine metabolic process	1.818093e-3
GO:0014029	neural crest formation	1.818093e-3
GO:0072080	nephron tubule development	1.860615e-3
GO:0009890	negative regulation of biosynthetic process	1.862088e-3
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	1.889605e-3
GO:0035089	establishment of apical/basal cell polarity	1.902795e-3
GO:0072088	nephron epithelium morphogenesis	1.913922e-3
GO:0048588	developmental cell growth	1.937303e-3
GO:0048368	lateral mesoderm development	1.940171e-3
GO:0032910	regulation of transforming growth factor beta3 production	1.940171e-3
GO:0046940	nucleoside monophosphate phosphorylation	1.952554e-3
GO:0006366	transcription from RNA polymerase II promoter	1.978805e-3
GO:0006344	maintenance of chromatin silencing	1.981130e-3
GO:0071786	endoplasmic reticulum tubular network organization	1.998075e-3
GO:0035385	Roundabout signaling pathway	1.998075e-3
GO:0060426	lung vasculature development	2.012168e-3
GO:0051298	centrosome duplication	2.030030e-3
GO:0031324	negative regulation of cellular metabolic process	2.054338e-3
GO:0003407	neural retina development	2.054484e-3
GO:0001843	neural tube closure	2.068906e-3
GO:0070934	CRD-mediated mRNA stabilization	2.069628e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.078755e-3
GO:0048598	embryonic morphogenesis	2.084622e-3
GO:0070544	histone H3-K36 demethylation	2.147744e-3
GO:0010092	specification of organ identity	2.194219e-3
GO:0009313	oligosaccharide catabolic process	2.200339e-3
GO:0000077	DNA damage checkpoint	2.233332e-3
GO:0006991	response to sterol depletion	2.238285e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2.238285e-3
GO:0072668	tubulin complex biogenesis	2.266054e-3
GO:0071503	response to heparin	2.354701e-3
GO:0045426	quinone cofactor biosynthetic process	2.354701e-3
GO:0042375	quinone cofactor metabolic process	2.363270e-3
GO:0006304	DNA modification	2.387039e-3
GO:0033026	negative regulation of mast cell apoptosis	2.396892e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	2.403009e-3
GO:0003017	lymph circulation	2.403009e-3
GO:0010629	negative regulation of gene expression	2.418675e-3
GO:0031987	locomotion involved in locomotory behavior	2.438893e-3
GO:0021675	nerve development	2.439102e-3
GO:0060606	tube closure	2.499649e-3
GO:0030237	female sex determination	2.558940e-3
GO:0006430	lysyl-tRNA aminoacylation	2.580316e-3
GO:0006689	ganglioside catabolic process	2.624568e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.654799e-3
GO:0050770	regulation of axonogenesis	2.661995e-3
GO:0009952	anterior/posterior pattern specification	2.665682e-3
GO:0002074	extraocular skeletal muscle development	2.763840e-3
GO:0060119	inner ear receptor cell development	2.776727e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	2.826364e-3
GO:0021681	cerebellar granular layer development	2.834175e-3
GO:0006863	purine base transport	2.864174e-3
GO:0060729	intestinal epithelial structure maintenance	2.864806e-3
GO:0045198	establishment of epithelial cell apical/basal polarity	2.871101e-3
GO:0014020	primary neural tube formation	2.957493e-3
GO:0061326	renal tubule development	2.965288e-3
GO:0031328	positive regulation of cellular biosynthetic process	3.092928e-3
GO:0006363	termination of RNA polymerase I transcription	3.160738e-3
GO:0008089	anterograde axon cargo transport	3.161019e-3
GO:0031570	DNA integrity checkpoint	3.164965e-3
GO:0044265	cellular macromolecule catabolic process	3.167844e-3
GO:0051097	negative regulation of helicase activity	3.205883e-3
GO:0044273	sulfur compound catabolic process	3.211592e-3
GO:0033238	regulation of cellular amine metabolic process	3.264246e-3
GO:0045408	regulation of interleukin-6 biosynthetic process	3.302291e-3
GO:0010634	positive regulation of epithelial cell migration	3.302291e-3
GO:0060463	lung lobe morphogenesis	3.362172e-3
GO:0006542	glutamine biosynthetic process	3.397186e-3
GO:0060841	venous blood vessel development	3.497325e-3
GO:0060914	heart formation	3.555624e-3
GO:0043060	meiotic metaphase I plate congression	3.575779e-3
GO:2000438	negative regulation of monocyte extravasation	3.575779e-3
GO:0080154	regulation of fertilization	3.575779e-3
GO:0035724	CD24 biosynthetic process	3.575779e-3
GO:0035723	interleukin-15-mediated signaling pathway	3.575779e-3
GO:0015684	ferrous iron transport	3.575779e-3
GO:0018205	peptidyl-lysine modification	3.580632e-3
GO:0048205	COPI coating of Golgi vesicle	3.608696e-3
GO:0030033	microvillus assembly	3.608696e-3
GO:0032933	SREBP-mediated signaling pathway	3.726055e-3
GO:0034213	quinolinate catabolic process	3.762442e-3
GO:0019439	aromatic compound catabolic process	3.777822e-3
GO:0072028	nephron morphogenesis	3.847875e-3
GO:0071108	protein K48-linked deubiquitination	3.902716e-3
GO:0048340	paraxial mesoderm morphogenesis	3.918452e-3
GO:0046449	creatinine metabolic process	3.947584e-3
GO:0016140	O-glycoside metabolic process	4.000095e-3
GO:0070100	negative regulation of chemokine-mediated signaling pathway	4.004307e-3
GO:0019941	modification-dependent protein catabolic process	4.023670e-3
GO:0010604	positive regulation of macromolecule metabolic process	4.064009e-3
GO:0090102	cochlea development	4.132063e-3
GO:0090162	establishment of epithelial cell polarity	4.163204e-3
GO:0060113	inner ear receptor cell differentiation	4.231173e-3
GO:0034616	response to laminar fluid shear stress	4.239541e-3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4.301382e-3
GO:0006825	copper ion transport	4.301382e-3
GO:0061034	olfactory bulb mitral cell layer development	4.320753e-3
GO:0016568	chromatin modification	4.466671e-3
GO:0061180	mammary gland epithelium development	4.498484e-3
GO:0001553	luteinization	4.564920e-3
GO:0006521	regulation of cellular amino acid metabolic process	4.589203e-3
GO:0030070	insulin processing	4.623001e-3
GO:0051310	metaphase plate congression	4.689789e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	4.720452e-3
GO:0021683	cerebellar granular layer morphogenesis	4.799444e-3
GO:0010984	regulation of lipoprotein particle clearance	4.800691e-3
GO:0006729	tetrahydrobiopterin biosynthetic process	4.800691e-3
GO:0021983	pituitary gland development	4.827151e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	4.905211e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.908042e-3
GO:0042503	tyrosine phosphorylation of Stat3 protein	5.042528e-3
GO:0009074	aromatic amino acid family catabolic process	5.046005e-3
GO:0006686	sphingomyelin biosynthetic process	5.070179e-3
GO:0060018	astrocyte fate commitment	5.070179e-3
GO:0072210	metanephric nephron development	5.087260e-3
GO:0050673	epithelial cell proliferation	5.172302e-3
GO:0046618	drug export	5.225196e-3
GO:0045596	negative regulation of cell differentiation	5.239382e-3
GO:0040008	regulation of growth	5.244471e-3
GO:0035264	multicellular organism growth	5.368784e-3
GO:0033147	negative regulation of estrogen receptor signaling pathway	5.396496e-3
GO:0046827	positive regulation of protein export from nucleus	5.418778e-3
GO:0060011	Sertoli cell proliferation	5.425188e-3
GO:0019222	regulation of metabolic process	5.454726e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	5.512354e-3
GO:0016137	glycoside metabolic process	5.512354e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	5.548024e-3
GO:0061301	cerebellum vasculature morphogenesis	5.632241e-3
GO:0048352	paraxial mesoderm structural organization	5.632241e-3
GO:0045964	positive regulation of dopamine metabolic process	5.632241e-3
GO:0021998	neural plate mediolateral regionalization	5.632241e-3
GO:0048194	Golgi vesicle budding	5.653249e-3
GO:0009072	aromatic amino acid family metabolic process	5.668034e-3
GO:0043632	modification-dependent macromolecule catabolic process	5.676304e-3
GO:0030879	mammary gland development	5.698730e-3
GO:0034728	nucleosome organization	5.700645e-3
GO:0003382	epithelial cell morphogenesis	5.705451e-3
GO:0009790	embryo development	5.715191e-3
GO:0030431	sleep	5.847386e-3
GO:0072092	ureteric bud invasion	5.894581e-3
GO:0035426	extracellular matrix-cell signaling	5.941728e-3
GO:0001885	endothelial cell development	5.943647e-3
GO:0010212	response to ionizing radiation	5.976192e-3
GO:0033261	regulation of S phase	6.048261e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	6.079944e-3
GO:0060535	trachea cartilage morphogenesis	6.090752e-3
GO:0002268	follicular dendritic cell differentiation	6.090752e-3
GO:0045636	positive regulation of melanocyte differentiation	6.234187e-3
GO:0016584	nucleosome positioning	6.343657e-3
GO:0042737	drug catabolic process	6.343657e-3
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	6.343657e-3
GO:0006533	aspartate catabolic process	6.471658e-3
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	6.525281e-3
GO:0009891	positive regulation of biosynthetic process	6.604905e-3
GO:0045634	regulation of melanocyte differentiation	6.613638e-3
GO:0006511	ubiquitin-dependent protein catabolic process	6.619636e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	6.680095e-3
GO:0007498	mesoderm development	6.683234e-3
GO:0051412	response to corticosterone stimulus	6.683619e-3
GO:0060290	transdifferentiation	6.731259e-3
GO:0006457	protein folding	6.755414e-3
GO:0051403	stress-activated MAPK cascade	6.786229e-3
GO:0009948	anterior/posterior axis specification	6.786404e-3
GO:0010870	positive regulation of receptor biosynthetic process	6.872923e-3
GO:0031441	negative regulation of mRNA 3'-end processing	6.984918e-3
GO:0009798	axis specification	7.007913e-3
GO:0065004	protein-DNA complex assembly	7.101985e-3
GO:0060084	synaptic transmission involved in micturition	7.152551e-3
GO:0050783	cocaine metabolic process	7.152551e-3
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	7.159167e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	7.259604e-3
GO:0040038	polar body extrusion after meiotic divisions	7.269745e-3
GO:0072197	ureter morphogenesis	7.320190e-3
GO:0060897	neural plate regionalization	7.341697e-3
GO:0033169	histone H3-K9 demethylation	7.341697e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	7.394942e-3
GO:0033555	multicellular organismal response to stress	7.457666e-3
GO:0045879	negative regulation of smoothened signaling pathway	7.477230e-3
GO:0048880	sensory system development	7.591080e-3
GO:0046627	negative regulation of insulin receptor signaling pathway	7.672130e-3
GO:0021801	cerebral cortex radial glia guided migration	7.722795e-3
GO:0048554	positive regulation of metalloenzyme activity	7.743542e-3
GO:0051297	centrosome organization	7.798939e-3
GO:0006516	glycoprotein catabolic process	7.807041e-3
GO:0030855	epithelial cell differentiation	7.834102e-3
GO:0061333	renal tubule morphogenesis	7.888315e-3
GO:0051085	chaperone mediated protein folding requiring cofactor	7.955794e-3
GO:0060041	retina development in camera-type eye	7.973471e-3
GO:0031325	positive regulation of cellular metabolic process	7.978844e-3
GO:0009649	entrainment of circadian clock	7.991288e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	8.119319e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0060299	negative regulation of sarcomere organization	2.794852e-10
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	2.794852e-10
GO:0070925	organelle assembly	4.660084e-10
GO:0006975	DNA damage induced protein phosphorylation	2.508045e-9
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.988816e-8
GO:0072355	histone H3-T3 phosphorylation	2.957493e-8
GO:0090086	negative regulation of protein deubiquitination	6.357251e-8
GO:0017158	regulation of calcium ion-dependent exocytosis	1.043486e-7
GO:0072075	metanephric mesenchyme development	1.236271e-7
GO:0045056	transcytosis	1.879016e-7
GO:0000045	autophagic vacuole assembly	2.290644e-7
GO:0071459	protein localization to chromosome, centromeric region	2.878004e-7
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	4.487744e-7
GO:0016068	type I hypersensitivity	4.487744e-7
GO:0006986	response to unfolded protein	5.089835e-7
GO:0001822	kidney development	6.566282e-7
GO:0071670	smooth muscle cell chemotaxis	8.728631e-7
GO:0060981	cell migration involved in coronary angiogenesis	8.728631e-7
GO:0006713	glucocorticoid catabolic process	8.728631e-7
GO:0007099	centriole replication	1.023614e-6
GO:0030505	inorganic diphosphate transport	1.073711e-6
GO:0051932	synaptic transmission, GABAergic	1.077671e-6
GO:0006756	AMP phosphorylation	1.576474e-6
GO:0030433	ER-associated protein catabolic process	1.644522e-6
GO:0010519	negative regulation of phospholipase activity	1.924483e-6
GO:0010467	gene expression	2.016188e-6
GO:0072074	kidney mesenchyme development	2.045556e-6
GO:0008208	C21-steroid hormone catabolic process	2.683045e-6
GO:0090084	negative regulation of inclusion body assembly	2.705728e-6
GO:0090085	regulation of protein deubiquitination	2.705728e-6
GO:0001656	metanephros development	2.956101e-6
GO:0072001	renal system development	3.387552e-6
GO:0015705	iodide transport	3.584974e-6
GO:0072239	metanephric glomerulus vasculature development	3.634431e-6
GO:0035966	response to topologically incorrect protein	4.124002e-6
GO:0046940	nucleoside monophosphate phosphorylation	4.348976e-6
GO:0009948	anterior/posterior axis specification	5.121127e-6
GO:0016236	macroautophagy	6.205016e-6
GO:0072203	cell proliferation involved in metanephros development	6.434216e-6
GO:0072172	mesonephric tubule formation	6.913317e-6
GO:0051204	protein insertion into mitochondrial membrane	9.912944e-6
GO:0007498	mesoderm development	1.046639e-5
GO:0051084	'de novo' posttranslational protein folding	1.083795e-5
GO:0032863	activation of Rac GTPase activity	1.109939e-5
GO:0032232	negative regulation of actin filament bundle assembly	1.196383e-5
GO:0033566	gamma-tubulin complex localization	1.362243e-5
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	1.483989e-5
GO:0006011	UDP-glucose metabolic process	1.483989e-5
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	1.534345e-5
GO:0072012	glomerulus vasculature development	1.571766e-5
GO:0072109	glomerular mesangium development	1.898733e-5
GO:0010457	centriole-centriole cohesion	1.934007e-5
GO:0003100	regulation of systemic arterial blood pressure by endothelin	2.343337e-5
GO:2000249	regulation of actin cytoskeleton reorganization	2.910168e-5
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	3.002853e-5
GO:0070301	cellular response to hydrogen peroxide	3.048606e-5
GO:0016070	RNA metabolic process	3.125591e-5
GO:0023061	signal release	3.276709e-5
GO:0010637	negative regulation of mitochondrial fusion	3.346057e-5
GO:0071279	cellular response to cobalt ion	3.346057e-5
GO:0007269	neurotransmitter secretion	3.491968e-5
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	3.528143e-5
GO:0045116	protein neddylation	3.534952e-5
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	3.534952e-5
GO:0007023	post-chaperonin tubulin folding pathway	3.594975e-5
GO:0090083	regulation of inclusion body assembly	3.903978e-5
GO:0032682	negative regulation of chemokine production	3.991312e-5
GO:0090218	positive regulation of lipid kinase activity	4.217097e-5
GO:0072111	cell proliferation involved in kidney development	4.271731e-5
GO:0072143	mesangial cell development	4.568314e-5
GO:0072224	metanephric glomerulus development	4.619773e-5
GO:0010001	glial cell differentiation	4.706759e-5
GO:0031023	microtubule organizing center organization	4.925064e-5
GO:0090304	nucleic acid metabolic process	5.182577e-5
GO:0006930	substrate-dependent cell migration, cell extension	5.443126e-5
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	6.116776e-5
GO:0032940	secretion by cell	6.434256e-5
GO:0072171	mesonephric tubule morphogenesis	6.553699e-5
GO:0009059	macromolecule biosynthetic process	6.596311e-5
GO:0019858	cytosine metabolic process	6.797130e-5
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	7.024776e-5
GO:0032916	positive regulation of transforming growth factor beta3 production	7.341554e-5
GO:0051297	centrosome organization	8.118596e-5
GO:0031133	regulation of axon diameter	8.119343e-5
GO:0018279	protein N-linked glycosylation via asparagine	8.197125e-5
GO:0072162	metanephric mesenchymal cell differentiation	8.587027e-5
GO:0071480	cellular response to gamma radiation	9.178779e-5
GO:0051001	negative regulation of nitric-oxide synthase activity	9.499360e-5
GO:0031077	post-embryonic camera-type eye development	9.588036e-5
GO:0048793	pronephros development	1.035298e-4
GO:0045687	positive regulation of glial cell differentiation	1.065191e-4
GO:0072277	metanephric glomerular capillary formation	1.092274e-4
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	1.125201e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	1.125201e-4
GO:0034614	cellular response to reactive oxygen species	1.186733e-4
GO:0070625	zymogen granule exocytosis	1.192107e-4
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.192107e-4
GO:0048240	sperm capacitation	1.202198e-4
GO:0006661	phosphatidylinositol biosynthetic process	1.218397e-4
GO:0034645	cellular macromolecule biosynthetic process	1.248040e-4
GO:0046474	glycerophospholipid biosynthetic process	1.249568e-4
GO:0035282	segmentation	1.275984e-4
GO:0003334	keratinocyte development	1.289163e-4
GO:0042501	serine phosphorylation of STAT protein	1.318272e-4
GO:0018106	peptidyl-histidine phosphorylation	1.379786e-4
GO:0042063	gliogenesis	1.444499e-4
GO:0045665	negative regulation of neuron differentiation	1.504571e-4
GO:0048627	myoblast development	1.551651e-4
GO:0019255	glucose 1-phosphate metabolic process	1.580742e-4
GO:0032536	regulation of cell projection size	1.640278e-4
GO:0014909	smooth muscle cell migration	1.844208e-4
GO:0035441	cell migration involved in vasculogenesis	1.844208e-4
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.854148e-4
GO:0032910	regulation of transforming growth factor beta3 production	1.854210e-4
GO:0006351	transcription, DNA-dependent	1.861297e-4
GO:0045662	negative regulation of myoblast differentiation	1.923909e-4
GO:0072259	metanephric interstitial cell development	1.935949e-4
GO:0072208	metanephric smooth muscle tissue development	1.935949e-4
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	1.935949e-4
GO:0072168	specification of anterior mesonephric tubule identity	1.935949e-4
GO:0072169	specification of posterior mesonephric tubule identity	1.935949e-4
GO:0072184	renal vesicle progenitor cell differentiation	1.935949e-4
GO:0061298	retina vasculature development in camera-type eye	2.040067e-4
GO:0032774	RNA biosynthetic process	2.082127e-4
GO:0048569	post-embryonic organ development	2.112643e-4
GO:0017156	calcium ion-dependent exocytosis	2.154146e-4
GO:0060459	left lung development	2.232381e-4
GO:0014812	muscle cell migration	2.272239e-4
GO:0048859	formation of anatomical boundary	2.283265e-4
GO:0006603	phosphocreatine metabolic process	2.283265e-4
GO:0043065	positive regulation of apoptosis	2.478735e-4
GO:0008360	regulation of cell shape	2.526302e-4
GO:0042921	glucocorticoid receptor signaling pathway	2.548085e-4
GO:0007501	mesodermal cell fate specification	2.621320e-4
GO:0016044	cellular membrane organization	2.749706e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	2.762940e-4
GO:0043550	regulation of lipid kinase activity	2.783102e-4
GO:0061024	membrane organization	2.963805e-4
GO:0002355	detection of tumor cell	2.964362e-4
GO:0046488	phosphatidylinositol metabolic process	3.130721e-4
GO:0071874	cellular response to norepinephrine stimulus	3.206322e-4
GO:0030878	thyroid gland development	3.237145e-4
GO:0070830	tight junction assembly	3.266751e-4
GO:0060046	regulation of acrosome reaction	3.294677e-4
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	3.318124e-4
GO:0032495	response to muramyl dipeptide	3.318124e-4
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	3.405514e-4
GO:0044260	cellular macromolecule metabolic process	3.408801e-4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.541530e-4
GO:0072182	regulation of nephron tubule epithelial cell differentiation	3.583590e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	3.599205e-4
GO:0035284	brain segmentation	3.599205e-4
GO:0034111	negative regulation of homotypic cell-cell adhesion	3.599205e-4
GO:0007256	activation of JNKK activity	3.760145e-4
GO:0032956	regulation of actin cytoskeleton organization	3.813808e-4
GO:0043068	positive regulation of programmed cell death	3.877721e-4
GO:0045213	neurotransmitter receptor metabolic process	3.910451e-4
GO:0045727	positive regulation of translation	4.011201e-4
GO:0008595	anterior/posterior axis specification, embryo	4.048036e-4
GO:0002347	response to tumor cell	4.108086e-4
GO:0090399	replicative senescence	4.139590e-4
GO:0035115	embryonic forelimb morphogenesis	4.144767e-4
GO:0016925	protein sumoylation	4.184708e-4
GO:0017157	regulation of exocytosis	4.199833e-4
GO:0048522	positive regulation of cellular process	4.247274e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	4.332897e-4
GO:0002826	negative regulation of T-helper 1 type immune response	4.332897e-4
GO:0000073	spindle pole body separation	4.332897e-4
GO:0051298	centrosome duplication	4.485930e-4
GO:0007379	segment specification	4.495677e-4
GO:0006338	chromatin remodeling	4.550797e-4
GO:0032855	positive regulation of Rac GTPase activity	4.556956e-4
GO:0021660	rhombomere 3 formation	4.582180e-4
GO:0021666	rhombomere 5 formation	4.582180e-4
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	4.675518e-4
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	4.675518e-4
GO:0021740	principal sensory nucleus of trigeminal nerve development	4.675518e-4
GO:0061141	lung ciliated cell differentiation	4.675518e-4
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	4.675518e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	4.833495e-4
GO:0021658	rhombomere 3 morphogenesis	4.918804e-4
GO:0007064	mitotic sister chromatid cohesion	4.994295e-4
GO:0072189	ureter development	5.226772e-4
GO:0051205	protein insertion into membrane	5.226772e-4
GO:0032970	regulation of actin filament-based process	5.232558e-4
GO:0000578	embryonic axis specification	5.262405e-4
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	5.271611e-4
GO:0018105	peptidyl-serine phosphorylation	5.333826e-4
GO:0007229	integrin-mediated signaling pathway	5.354776e-4
GO:0022604	regulation of cell morphogenesis	5.383644e-4
GO:0072079	nephron tubule formation	5.592065e-4
GO:0043631	RNA polyadenylation	5.726117e-4
GO:0046501	protoporphyrinogen IX metabolic process	5.772879e-4
GO:0048532	anatomical structure arrangement	6.025262e-4
GO:0045017	glycerolipid biosynthetic process	6.121596e-4
GO:0009798	axis specification	6.234692e-4
GO:0003167	atrioventricular bundle cell differentiation	6.383347e-4
GO:0060931	sinoatrial node cell development	6.383347e-4
GO:0042981	regulation of apoptosis	6.787215e-4
GO:0032902	nerve growth factor production	6.909427e-4
GO:0002331	pre-B cell allelic exclusion	6.909427e-4
GO:0000186	activation of MAPKK activity	7.002365e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	7.074198e-4
GO:0009880	embryonic pattern specification	7.108464e-4
GO:0072133	metanephric mesenchyme morphogenesis	7.181324e-4
GO:0072006	nephron development	7.273011e-4
GO:0001710	mesodermal cell fate commitment	7.540336e-4
GO:0043067	regulation of programmed cell death	7.868035e-4
GO:2000573	positive regulation of DNA biosynthetic process	8.112976e-4
GO:0090185	negative regulation of kidney development	8.112976e-4
GO:0015760	glucose-6-phosphate transport	8.112976e-4
GO:0042044	fluid transport	8.287183e-4
GO:0072161	mesenchymal cell differentiation involved in kidney development	8.300535e-4
GO:0050774	negative regulation of dendrite morphogenesis	8.303024e-4
GO:0060012	synaptic transmission, glycinergic	8.320669e-4
GO:0046103	inosine biosynthetic process	8.320669e-4
GO:0006154	adenosine catabolic process	8.320669e-4
GO:0032769	negative regulation of monooxygenase activity	8.327900e-4
GO:0048524	positive regulation of viral reproduction	8.485087e-4
GO:0060236	regulation of mitotic spindle organization	8.831392e-4
GO:0010991	negative regulation of SMAD protein complex assembly	8.831392e-4
GO:0048332	mesoderm morphogenesis	8.931225e-4
GO:0021700	developmental maturation	9.194567e-4
GO:0060326	cell chemotaxis	9.211895e-4
GO:0046887	positive regulation of hormone secretion	9.245273e-4
GO:0016572	histone phosphorylation	9.404333e-4
GO:0045792	negative regulation of cell size	9.419760e-4
GO:0014826	vein smooth muscle contraction	9.419760e-4
GO:0090183	regulation of kidney development	9.462457e-4
GO:0014015	positive regulation of gliogenesis	9.532583e-4
GO:0032535	regulation of cellular component size	1.012321e-3
GO:0006506	GPI anchor biosynthetic process	1.012411e-3
GO:0072081	specification of nephron tubule identity	1.026720e-3
GO:0001780	neutrophil homeostasis	1.026720e-3
GO:0032321	positive regulation of Rho GTPase activity	1.030481e-3
GO:0019358	nicotinate nucleotide salvage	1.062259e-3
GO:0021831	embryonic olfactory bulb interneuron precursor migration	1.062259e-3
GO:0010085	polarity specification of proximal/distal axis	1.062259e-3
GO:0006409	tRNA export from nucleus	1.062259e-3
GO:0010822	positive regulation of mitochondrion organization	1.065330e-3
GO:0033205	cell cycle cytokinesis	1.098429e-3
GO:0090197	positive regulation of chemokine secretion	1.099924e-3
GO:0051225	spindle assembly	1.208062e-3
GO:0051354	negative regulation of oxidoreductase activity	1.268289e-3
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.270836e-3
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	1.270836e-3
GO:0072202	cell differentiation involved in metanephros development	1.271674e-3
GO:0021773	striatal medium spiny neuron differentiation	1.310918e-3
GO:0060921	sinoatrial node cell differentiation	1.349155e-3
GO:0051252	regulation of RNA metabolic process	1.357882e-3
GO:0046486	glycerolipid metabolic process	1.361589e-3
GO:0010941	regulation of cell death	1.377994e-3
GO:0018193	peptidyl-amino acid modification	1.385973e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	1.387038e-3
GO:0007097	nuclear migration	1.428880e-3
GO:0046102	inosine metabolic process	1.436810e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	1.436810e-3
GO:0045109	intermediate filament organization	1.446007e-3
GO:0007109	cytokinesis, completion of separation	1.461308e-3
GO:0050892	intestinal absorption	1.462231e-3
GO:0072164	mesonephric tubule development	1.476519e-3
GO:0031958	corticosteroid receptor signaling pathway	1.476519e-3
GO:0003002	regionalization	1.483773e-3
GO:0007033	vacuole organization	1.500028e-3
GO:0016192	vesicle-mediated transport	1.527667e-3
GO:0006378	mRNA polyadenylation	1.544626e-3
GO:0051451	myoblast migration	1.548094e-3
GO:0019348	dolichol metabolic process	1.548094e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.548094e-3
GO:0051254	positive regulation of RNA metabolic process	1.561029e-3
GO:0048711	positive regulation of astrocyte differentiation	1.563030e-3
GO:0046148	pigment biosynthetic process	1.612188e-3
GO:0048863	stem cell differentiation	1.614645e-3
GO:0035909	aorta morphogenesis	1.617764e-3
GO:0010611	regulation of cardiac muscle hypertrophy	1.630850e-3
GO:0001987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	1.658832e-3
GO:0045818	negative regulation of glycogen catabolic process	1.658832e-3
GO:0072110	glomerular mesangial cell proliferation	1.672758e-3
GO:0060932	His-Purkinje system cell differentiation	1.689090e-3
GO:0060926	pacemaker cell development	1.689090e-3
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.693124e-3
GO:0010942	positive regulation of cell death	1.720582e-3
GO:0032494	response to peptidoglycan	1.771740e-3
GO:0048662	negative regulation of smooth muscle cell proliferation	1.820345e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.831162e-3
GO:0035269	protein O-linked mannosylation	1.831162e-3
GO:0033590	response to cobalamin	1.831162e-3
GO:0007144	female meiosis I	1.831162e-3
GO:0051148	negative regulation of muscle cell differentiation	1.831171e-3
GO:0060708	spongiotrophoblast differentiation	1.835000e-3
GO:0071044	histone mRNA catabolic process	1.847931e-3
GO:0051402	neuron apoptosis	1.893928e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.893928e-3
GO:0045212	neurotransmitter receptor biosynthetic process	1.906636e-3
GO:0031987	locomotion involved in locomotory behavior	1.906636e-3
GO:0009225	nucleotide-sugar metabolic process	1.913873e-3
GO:0000910	cytokinesis	1.935770e-3
GO:0035404	histone-serine phosphorylation	2.092049e-3
GO:0046884	follicle-stimulating hormone secretion	2.092049e-3
GO:0032275	luteinizing hormone secretion	2.092049e-3
GO:0010614	negative regulation of cardiac muscle hypertrophy	2.092049e-3
GO:0042471	ear morphogenesis	2.109910e-3
GO:0006783	heme biosynthetic process	2.124272e-3
GO:0055091	phospholipid homeostasis	2.140451e-3
GO:0009952	anterior/posterior pattern specification	2.147053e-3
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	2.152247e-3
GO:0090196	regulation of chemokine secretion	2.164422e-3
GO:0007179	transforming growth factor beta receptor signaling pathway	2.173929e-3
GO:0055006	cardiac cell development	2.206171e-3
GO:0060712	spongiotrophoblast layer development	2.214265e-3
GO:0022614	membrane to membrane docking	2.214265e-3
GO:0000189	MAPK import into nucleus	2.294598e-3
GO:0016568	chromatin modification	2.317959e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2.320726e-3
GO:0014743	regulation of muscle hypertrophy	2.353431e-3
GO:0046777	protein autophosphorylation	2.366414e-3
GO:0046903	secretion	2.381706e-3
GO:2000648	positive regulation of stem cell proliferation	2.471898e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	2.491956e-3
GO:0072194	kidney smooth muscle tissue development	2.522625e-3
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	2.522625e-3
GO:0014807	regulation of somitogenesis	2.522625e-3
GO:0042472	inner ear morphogenesis	2.523754e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	2.565484e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	2.565484e-3
GO:0035405	histone-threonine phosphorylation	2.565484e-3
GO:0040023	establishment of nucleus localization	2.602592e-3
GO:0015698	inorganic anion transport	2.614742e-3
GO:0042759	long-chain fatty acid biosynthetic process	2.630929e-3
GO:0006139	nucleobase-containing compound metabolic process	2.704178e-3
GO:0051153	regulation of striated muscle cell differentiation	2.721188e-3
GO:0006650	glycerophospholipid metabolic process	2.749763e-3
GO:0090280	positive regulation of calcium ion import	2.757772e-3
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	2.757772e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	2.757772e-3
GO:0043297	apical junction assembly	2.820567e-3
GO:0006917	induction of apoptosis	2.827703e-3
GO:0003163	sinoatrial node development	2.831041e-3
GO:0051901	positive regulation of mitochondrial depolarization	2.831041e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	2.832813e-3
GO:0032608	interferon-beta production	2.832813e-3
GO:0007089	traversing start control point of mitotic cell cycle	2.832813e-3
GO:0090066	regulation of anatomical structure size	2.846731e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	2.870443e-3
GO:0006325	chromatin organization	2.933925e-3
GO:0035904	aorta development	2.965913e-3
GO:0003161	cardiac conduction system development	2.973746e-3
GO:0007423	sensory organ development	2.993155e-3
GO:0006807	nitrogen compound metabolic process	2.996220e-3
GO:0060297	regulation of sarcomere organization	3.013291e-3
GO:0001655	urogenital system development	3.024173e-3
GO:0034394	protein localization at cell surface	3.073958e-3
GO:0007354	zygotic determination of anterior/posterior axis, embryo	3.096418e-3
GO:0006897	endocytosis	3.112727e-3
GO:0060920	pacemaker cell differentiation	3.117146e-3
GO:0007098	centrosome cycle	3.129508e-3
GO:0048469	cell maturation	3.150392e-3
GO:0006833	water transport	3.158134e-3
GO:0070972	protein localization in endoplasmic reticulum	3.166113e-3
GO:0008637	apoptotic mitochondrial changes	3.175660e-3
GO:0006505	GPI anchor metabolic process	3.207967e-3
GO:0010639	negative regulation of organelle organization	3.237639e-3
GO:0012502	induction of programmed cell death	3.270925e-3
GO:0010556	regulation of macromolecule biosynthetic process	3.297938e-3
GO:0042770	signal transduction in response to DNA damage	3.321412e-3
GO:0030216	keratinocyte differentiation	3.325327e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	3.349901e-3
GO:0042310	vasoconstriction	3.361699e-3
GO:0060509	Type I pneumocyte differentiation	3.378177e-3
GO:0048280	vesicle fusion with Golgi apparatus	3.380015e-3
GO:0033299	secretion of lysosomal enzymes	3.380015e-3
GO:0006269	DNA replication, synthesis of RNA primer	3.380015e-3
GO:0060973	cell migration involved in heart development	3.381062e-3
GO:0021604	cranial nerve structural organization	3.381062e-3
GO:0034110	regulation of homotypic cell-cell adhesion	3.424808e-3
GO:0007009	plasma membrane organization	3.433493e-3
GO:0006189	'de novo' IMP biosynthetic process	3.451361e-3
GO:0042440	pigment metabolic process	3.554289e-3
GO:0071870	cellular response to catecholamine stimulus	3.662920e-3
GO:0006281	DNA repair	3.747828e-3
GO:0050792	regulation of viral reproduction	3.819129e-3
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3.865491e-3
GO:0060948	cardiac vascular smooth muscle cell development	3.879148e-3
GO:0043117	positive regulation of vascular permeability	3.879148e-3
GO:0019673	GDP-mannose metabolic process	3.879148e-3
GO:0051641	cellular localization	3.911283e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.962600e-3
GO:0006497	protein lipidation	3.982220e-3
GO:0060284	regulation of cell development	4.047551e-3
GO:0071173	spindle assembly checkpoint	4.108905e-3
GO:0014741	negative regulation of muscle hypertrophy	4.108905e-3
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	4.155630e-3
GO:0017121	phospholipid scrambling	4.155630e-3
GO:0034340	response to type I interferon	4.155630e-3
GO:0043502	regulation of muscle adaptation	4.264432e-3
GO:0048318	axial mesoderm development	4.299089e-3
GO:0021569	rhombomere 3 development	4.299089e-3
GO:0042542	response to hydrogen peroxide	4.372560e-3
GO:0043154	negative regulation of caspase activity	4.438978e-3
GO:0042178	xenobiotic catabolic process	4.487419e-3
GO:0006355	regulation of transcription, DNA-dependent	4.488953e-3
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	4.618358e-3
GO:0045596	negative regulation of cell differentiation	4.678585e-3
GO:0018209	peptidyl-serine modification	4.704435e-3
GO:0007088	regulation of mitosis	4.715945e-3
GO:0051494	negative regulation of cytoskeleton organization	4.759362e-3
GO:0051147	regulation of muscle cell differentiation	4.763279e-3
GO:0000920	cytokinetic cell separation	4.767523e-3
GO:0010604	positive regulation of macromolecule metabolic process	4.776744e-3
GO:0014031	mesenchymal cell development	4.844025e-3
GO:0090004	positive regulation of establishment of protein localization in plasma membrane	4.878521e-3
GO:0022603	regulation of anatomical structure morphogenesis	4.933946e-3
GO:0060460	left lung morphogenesis	4.950817e-3
GO:0035928	rRNA import into mitochondrion	4.950817e-3
GO:0014040	positive regulation of Schwann cell differentiation	4.950817e-3
GO:0035435	phosphate ion transmembrane transport	4.950817e-3
GO:0018202	peptidyl-histidine modification	4.975919e-3
GO:0030002	cellular anion homeostasis	4.986566e-3
GO:0021571	rhombomere 5 development	5.031762e-3
GO:0046013	regulation of T cell homeostatic proliferation	5.031762e-3
GO:0007352	zygotic specification of dorsal/ventral axis	5.031762e-3
GO:0034641	cellular nitrogen compound metabolic process	5.075445e-3
GO:0032862	activation of Rho GTPase activity	5.113524e-3
GO:0071695	anatomical structure maturation	5.192746e-3
GO:0060319	primitive erythrocyte differentiation	5.272394e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	5.272394e-3
GO:0010159	specification of organ position	5.322643e-3
GO:0021960	anterior commissure morphogenesis	5.354270e-3
GO:0045685	regulation of glial cell differentiation	5.362624e-3
GO:0007062	sister chromatid cohesion	5.506800e-3
GO:0050434	positive regulation of viral transcription	5.610713e-3
GO:0032642	regulation of chemokine production	5.711440e-3
GO:0010468	regulation of gene expression	5.731621e-3
GO:0035767	endothelial cell chemotaxis	5.781480e-3
GO:0010557	positive regulation of macromolecule biosynthetic process	5.782762e-3
GO:0071174	mitotic cell cycle spindle checkpoint	5.815302e-3
GO:0060556	regulation of vitamin D biosynthetic process	5.815302e-3
GO:0019987	negative regulation of anti-apoptosis	5.815302e-3
GO:0006613	cotranslational protein targeting to membrane	5.815302e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	5.841908e-3
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	5.915972e-3
GO:0007389	pattern specification process	5.924119e-3
GO:0072089	stem cell proliferation	5.967431e-3
GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	5.967431e-3
GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	5.967431e-3
GO:0048327	axial mesodermal cell fate specification	5.967431e-3
GO:0006552	leucine catabolic process	5.967431e-3
GO:0030844	positive regulation of intermediate filament depolymerization	5.967431e-3
GO:0002085	inhibition of neuroepithelial cell differentiation	5.967431e-3
GO:0032814	regulation of natural killer cell activation	6.128641e-3
GO:0042267	natural killer cell mediated cytotoxicity	6.176382e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	6.290221e-3
GO:0043583	ear development	6.389937e-3
GO:0090307	spindle assembly involved in mitosis	6.407851e-3
GO:0021612	facial nerve structural organization	6.407851e-3
GO:0048319	axial mesoderm morphogenesis	6.407851e-3
GO:0042168	heme metabolic process	6.470550e-3
GO:0060977	coronary vasculature morphogenesis	6.659235e-3
GO:0048762	mesenchymal cell differentiation	6.701715e-3
GO:0035886	vascular smooth muscle cell differentiation	6.731478e-3
GO:0031577	spindle checkpoint	6.786952e-3
GO:0000460	maturation of 5.8S rRNA	6.786952e-3
GO:0051693	actin filament capping	6.861978e-3
GO:0014910	regulation of smooth muscle cell migration	6.938919e-3
GO:0072017	distal tubule development	7.018363e-3
GO:0072193	ureter smooth muscle cell differentiation	7.021606e-3
GO:0031579	membrane raft organization	7.090824e-3
GO:0016074	snoRNA metabolic process	7.090824e-3
GO:0002076	osteoblast development	7.158266e-3
GO:2001020	regulation of response to DNA damage stimulus	7.161298e-3
GO:2000243	positive regulation of reproductive process	7.213006e-3
GO:0072104	glomerular capillary formation	7.335732e-3
GO:0048864	stem cell development	7.480714e-3
GO:0045837	negative regulation of membrane potential	7.507798e-3
GO:0042552	myelination	7.579296e-3
GO:0061004	pattern specification involved in kidney development	7.584601e-3
GO:0019827	stem cell maintenance	7.615405e-3
GO:0006402	mRNA catabolic process	7.652743e-3
GO:0006887	exocytosis	7.673840e-3
GO:0006474	N-terminal protein amino acid acetylation	7.688171e-3
GO:0072078	nephron tubule morphogenesis	7.860693e-3
GO:0043254	regulation of protein complex assembly	7.892249e-3
GO:0009650	UV protection	7.916638e-3
GO:0031333	negative regulation of protein complex assembly	7.924106e-3
GO:0032816	positive regulation of natural killer cell activation	7.981350e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	8.028080e-3
GO:0030730	sequestering of triglyceride	8.028080e-3
GO:0043010	camera-type eye development	8.306526e-3
GO:0034767	positive regulation of ion transmembrane transport	8.399102e-3
GO:0060840	artery development	8.401860e-3
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	8.530106e-3
GO:0042633	hair cycle	8.572266e-3
GO:0051493	regulation of cytoskeleton organization	8.594372e-3
GO:0051173	positive regulation of nitrogen compound metabolic process	8.605063e-3
GO:0001837	epithelial to mesenchymal transition	8.662890e-3
GO:0042157	lipoprotein metabolic process	8.722451e-3
GO:0045893	positive regulation of transcription, DNA-dependent	8.788714e-3
GO:0072215	regulation of metanephros development	8.802685e-3
GO:0071436	sodium ion export	8.935983e-3
GO:0071479	cellular response to ionizing radiation	8.979698e-3