Novel motif:136

name:	motif136_GTCTGCGTCTCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	7.522400e-16
GO:0048266	behavioral response to pain	8.549039e-13
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	7.971425e-11
GO:0045994	positive regulation of translational initiation by iron	1.075178e-10
GO:0002037	negative regulation of L-glutamate transport	1.075178e-10
GO:0003009	skeletal muscle contraction	2.722083e-10
GO:0051533	positive regulation of NFAT protein import into nucleus	3.747504e-10
GO:0006447	regulation of translational initiation by iron	5.661582e-10
GO:0050881	musculoskeletal movement	9.332360e-10
GO:0002761	regulation of myeloid leukocyte differentiation	2.504013e-9
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	2.756526e-9
GO:0042506	tyrosine phosphorylation of Stat5 protein	6.929905e-9
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	8.475426e-9
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.124418e-8
GO:0002922	positive regulation of humoral immune response	1.656191e-8
GO:0051956	negative regulation of amino acid transport	1.828583e-8
GO:0030225	macrophage differentiation	2.354672e-8
GO:0002861	regulation of inflammatory response to antigenic stimulus	2.585420e-8
GO:0002920	regulation of humoral immune response	3.323776e-8
GO:0044236	multicellular organismal metabolic process	5.632153e-8
GO:0055093	response to hyperoxia	6.514266e-8
GO:0008625	induction of apoptosis via death domain receptors	7.068589e-8
GO:0010765	positive regulation of sodium ion transport	9.324983e-8
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	9.755443e-8
GO:0006958	complement activation, classical pathway	1.062444e-7
GO:0006956	complement activation	1.423207e-7
GO:0045662	negative regulation of myoblast differentiation	2.409421e-7
GO:0046985	positive regulation of hemoglobin biosynthetic process	2.486069e-7
GO:0043973	histone H3-K4 acetylation	2.486069e-7
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	2.486069e-7
GO:0060033	anatomical structure regression	2.917756e-7
GO:0061048	negative regulation of branching involved in lung morphogenesis	3.001939e-7
GO:0045835	negative regulation of meiosis	3.986964e-7
GO:0010868	negative regulation of triglyceride biosynthetic process	4.250076e-7
GO:0030574	collagen catabolic process	4.295102e-7
GO:0002573	myeloid leukocyte differentiation	4.764832e-7
GO:0010866	regulation of triglyceride biosynthetic process	5.083788e-7
GO:0045661	regulation of myoblast differentiation	5.174837e-7
GO:0090207	regulation of triglyceride metabolic process	5.795036e-7
GO:0045112	integrin biosynthetic process	6.262775e-7
GO:0006959	humoral immune response	6.467553e-7
GO:0002455	humoral immune response mediated by circulating immunoglobulin	6.676489e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	7.394014e-7
GO:0046108	uridine metabolic process	7.394014e-7
GO:0032929	negative regulation of superoxide anion generation	8.104019e-7
GO:0010625	positive regulation of Schwann cell proliferation	8.626079e-7
GO:0044243	multicellular organismal catabolic process	8.724804e-7
GO:0060319	primitive erythrocyte differentiation	1.106258e-6
GO:0002575	basophil chemotaxis	1.106258e-6
GO:0048771	tissue remodeling	1.157032e-6
GO:0048705	skeletal system morphogenesis	1.286591e-6
GO:0030828	positive regulation of cGMP biosynthetic process	1.407292e-6
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.435164e-6
GO:0002678	positive regulation of chronic inflammatory response	1.453326e-6
GO:0045760	positive regulation of action potential	1.471725e-6
GO:0044259	multicellular organismal macromolecule metabolic process	1.476664e-6
GO:0035441	cell migration involved in vasculogenesis	1.987525e-6
GO:0071347	cellular response to interleukin-1	2.030038e-6
GO:0001300	chronological cell aging	2.396258e-6
GO:0030852	regulation of granulocyte differentiation	2.431516e-6
GO:0032963	collagen metabolic process	2.566136e-6
GO:0045948	positive regulation of translational initiation	2.588982e-6
GO:0030224	monocyte differentiation	2.768941e-6
GO:0051216	cartilage development	2.865795e-6
GO:0002676	regulation of chronic inflammatory response	3.126844e-6
GO:0030826	regulation of cGMP biosynthetic process	3.244845e-6
GO:0051023	regulation of immunoglobulin secretion	3.639656e-6
GO:0003417	growth plate cartilage development	3.756841e-6
GO:0035304	regulation of protein dephosphorylation	3.992101e-6
GO:0030100	regulation of endocytosis	4.028738e-6
GO:0042508	tyrosine phosphorylation of Stat1 protein	4.348303e-6
GO:0002036	regulation of L-glutamate transport	4.610084e-6
GO:0002230	positive regulation of defense response to virus by host	5.049448e-6
GO:0045649	regulation of macrophage differentiation	5.075987e-6
GO:0050830	defense response to Gram-positive bacterium	5.254720e-6
GO:0003416	endochondral bone growth	5.724888e-6
GO:0051971	positive regulation of transmission of nerve impulse	5.771541e-6
GO:0001894	tissue homeostasis	6.501925e-6
GO:0035356	cellular triglyceride homeostasis	6.929625e-6
GO:2000097	regulation of smooth muscle cell-matrix adhesion	7.213027e-6
GO:0046849	bone remodeling	7.228061e-6
GO:0090279	regulation of calcium ion import	7.430299e-6
GO:0031646	positive regulation of neurological system process	7.573561e-6
GO:0035725	sodium ion transmembrane transport	8.173506e-6
GO:0006540	glutamate decarboxylation to succinate	8.388227e-6
GO:0050806	positive regulation of synaptic transmission	8.623676e-6
GO:0002016	regulation of blood volume by renin-angiotensin	1.027815e-5
GO:0048265	response to pain	1.075568e-5
GO:0042391	regulation of membrane potential	1.102926e-5
GO:0002028	regulation of sodium ion transport	1.107040e-5
GO:0035305	negative regulation of dephosphorylation	1.293095e-5
GO:0045651	positive regulation of macrophage differentiation	1.330163e-5
GO:0060696	regulation of phospholipid catabolic process	1.360186e-5
GO:0090209	negative regulation of triglyceride metabolic process	1.368547e-5
GO:0030853	negative regulation of granulocyte differentiation	1.387286e-5
GO:0043982	histone H4-K8 acetylation	1.395763e-5
GO:0043981	histone H4-K5 acetylation	1.395763e-5
GO:0072277	metanephric glomerular capillary formation	1.404737e-5
GO:0046684	response to pyrethroid	1.522882e-5
GO:0046984	regulation of hemoglobin biosynthetic process	1.535217e-5
GO:0035272	exocrine system development	1.567374e-5
GO:0007422	peripheral nervous system development	1.638115e-5
GO:0035036	sperm-egg recognition	1.647962e-5
GO:0006707	cholesterol catabolic process	1.701812e-5
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.728507e-5
GO:0002675	positive regulation of acute inflammatory response	1.769565e-5
GO:0090197	positive regulation of chemokine secretion	1.849802e-5
GO:0032754	positive regulation of interleukin-5 production	1.856757e-5
GO:0007296	vitellogenesis	1.864182e-5
GO:0043271	negative regulation of ion transport	1.931487e-5
GO:0034502	protein localization to chromosome	1.975542e-5
GO:0035306	positive regulation of dephosphorylation	1.991649e-5
GO:0001508	regulation of action potential	2.598686e-5
GO:0035307	positive regulation of protein dephosphorylation	2.606281e-5
GO:0002316	follicular B cell differentiation	2.766017e-5
GO:0070079	histone H4-R3 demethylation	2.805420e-5
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.805420e-5
GO:0070078	histone H3-R2 demethylation	2.805420e-5
GO:0035117	embryonic arm morphogenesis	2.903728e-5
GO:0016337	cell-cell adhesion	2.964604e-5
GO:0048661	positive regulation of smooth muscle cell proliferation	3.060556e-5
GO:0051798	positive regulation of hair follicle development	3.174250e-5
GO:0060688	regulation of morphogenesis of a branching structure	3.177141e-5
GO:0045926	negative regulation of growth	3.189472e-5
GO:0010624	regulation of Schwann cell proliferation	3.200927e-5
GO:0060591	chondroblast differentiation	3.203771e-5
GO:0071585	detoxification of cadmium ion	3.264995e-5
GO:0060561	apoptosis involved in morphogenesis	3.311787e-5
GO:0002673	regulation of acute inflammatory response	3.417763e-5
GO:0071670	smooth muscle cell chemotaxis	3.617574e-5
GO:0060981	cell migration involved in coronary angiogenesis	3.617574e-5
GO:0060977	coronary vasculature morphogenesis	3.670868e-5
GO:0039020	pronephric nephron tubule development	3.819140e-5
GO:0035565	regulation of pronephros size	3.819140e-5
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	3.819140e-5
GO:0002763	positive regulation of myeloid leukocyte differentiation	4.337298e-5
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4.352238e-5
GO:0033138	positive regulation of peptidyl-serine phosphorylation	4.454909e-5
GO:0007159	leukocyte cell-cell adhesion	4.651787e-5
GO:0090196	regulation of chemokine secretion	4.713301e-5
GO:0009988	cell-cell recognition	4.801379e-5
GO:0060349	bone morphogenesis	4.968972e-5
GO:0048167	regulation of synaptic plasticity	4.980550e-5
GO:0052565	response to defense-related host nitric oxide production	5.172985e-5
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	5.438563e-5
GO:0060754	positive regulation of mast cell chemotaxis	5.489578e-5
GO:0005984	disaccharide metabolic process	5.504230e-5
GO:0046902	regulation of mitochondrial membrane permeability	5.620597e-5
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	5.822904e-5
GO:0042088	T-helper 1 type immune response	6.107849e-5
GO:0071258	cellular response to gravity	6.148238e-5
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	6.148238e-5
GO:0061044	negative regulation of vascular wound healing	6.148238e-5
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	6.148238e-5
GO:0045721	negative regulation of gluconeogenesis	6.176447e-5
GO:0010900	negative regulation of phosphatidylcholine catabolic process	6.212092e-5
GO:0071803	positive regulation of podosome assembly	6.501432e-5
GO:0044403	symbiosis, encompassing mutualism through parasitism	6.749871e-5
GO:0006972	hyperosmotic response	6.849706e-5
GO:0015696	ammonium transport	7.030656e-5
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	7.363607e-5
GO:0001798	positive regulation of type IIa hypersensitivity	7.530817e-5
GO:2000465	regulation of glycogen (starch) synthase activity	7.558826e-5
GO:0045684	positive regulation of epidermis development	7.627874e-5
GO:0043088	regulation of Cdc42 GTPase activity	7.627874e-5
GO:0045940	positive regulation of steroid metabolic process	7.712811e-5
GO:0032241	positive regulation of nucleobase-containing compound transport	7.968894e-5
GO:0030099	myeloid cell differentiation	8.363688e-5
GO:0007612	learning	8.690512e-5
GO:0018125	peptidyl-cysteine methylation	8.846764e-5
GO:0002712	regulation of B cell mediated immunity	8.888760e-5
GO:0001649	osteoblast differentiation	8.992037e-5
GO:0071168	protein localization to chromatin	9.220285e-5
GO:0045453	bone resorption	9.584711e-5
GO:0002889	regulation of immunoglobulin mediated immune response	9.878664e-5
GO:0071456	cellular response to hypoxia	9.905880e-5
GO:0060557	positive regulation of vitamin D biosynthetic process	1.015599e-4
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	1.017937e-4
GO:0048742	regulation of skeletal muscle fiber development	1.018877e-4
GO:0072385	minus-end-directed organelle transport along microtubule	1.019970e-4
GO:0033135	regulation of peptidyl-serine phosphorylation	1.027888e-4
GO:0072376	protein activation cascade	1.029498e-4
GO:0002762	negative regulation of myeloid leukocyte differentiation	1.036811e-4
GO:2000369	regulation of clathrin-mediated endocytosis	1.071015e-4
GO:0010959	regulation of metal ion transport	1.079568e-4
GO:0060291	long-term synaptic potentiation	1.085874e-4
GO:0060627	regulation of vesicle-mediated transport	1.095791e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.118712e-4
GO:0051701	interaction with host	1.181871e-4
GO:0006538	glutamate catabolic process	1.188146e-4
GO:0060348	bone development	1.206357e-4
GO:0090281	negative regulation of calcium ion import	1.214602e-4
GO:0071584	negative regulation of zinc ion import	1.214602e-4
GO:0051497	negative regulation of stress fiber assembly	1.226714e-4
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	1.234494e-4
GO:0002274	myeloid leukocyte activation	1.268550e-4
GO:0006534	cysteine metabolic process	1.270946e-4
GO:0002250	adaptive immune response	1.288963e-4
GO:0006998	nuclear envelope organization	1.327589e-4
GO:0042117	monocyte activation	1.359231e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.378858e-4
GO:0032571	response to vitamin K	1.384215e-4
GO:0000413	protein peptidyl-prolyl isomerization	1.428750e-4
GO:0034765	regulation of ion transmembrane transport	1.464829e-4
GO:0032959	inositol trisphosphate biosynthetic process	1.515388e-4
GO:0060087	relaxation of vascular smooth muscle	1.553135e-4
GO:0044319	wound healing, spreading of cells	1.565453e-4
GO:0045670	regulation of osteoclast differentiation	1.613572e-4
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.666213e-4
GO:0001933	negative regulation of protein phosphorylation	1.679703e-4
GO:0070482	response to oxygen levels	1.680023e-4
GO:0019048	virus-host interaction	1.708925e-4
GO:0035573	N-terminal peptidyl-serine trimethylation	1.713694e-4
GO:0035572	N-terminal peptidyl-serine dimethylation	1.713694e-4
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.713694e-4
GO:0018016	N-terminal peptidyl-proline dimethylation	1.713694e-4
GO:0016226	iron-sulfur cluster assembly	1.733594e-4
GO:0046732	active induction of host immune response by virus	1.757880e-4
GO:0035313	wound healing, spreading of epidermal cells	1.764932e-4
GO:0051055	negative regulation of lipid biosynthetic process	1.791136e-4
GO:0035771	interleukin-4-mediated signaling pathway	1.888063e-4
GO:0061037	negative regulation of cartilage development	1.955974e-4
GO:0046730	induction of host immune response by virus	1.981065e-4
GO:0043269	regulation of ion transport	1.981109e-4
GO:0071034	CUT catabolic process	2.040942e-4
GO:0045541	negative regulation of cholesterol biosynthetic process	2.040942e-4
GO:0015747	urate transport	2.042891e-4
GO:0045630	positive regulation of T-helper 2 cell differentiation	2.149915e-4
GO:0007435	salivary gland morphogenesis	2.152127e-4
GO:0001502	cartilage condensation	2.193421e-4
GO:0003073	regulation of systemic arterial blood pressure	2.217906e-4
GO:0005989	lactose biosynthetic process	2.237728e-4
GO:0044140	negative regulation of growth of symbiont on or near host surface	2.382025e-4
GO:0071316	cellular response to nicotine	2.404254e-4
GO:0002883	regulation of hypersensitivity	2.404563e-4
GO:0019228	regulation of action potential in neuron	2.413770e-4
GO:0010739	positive regulation of protein kinase A signaling cascade	2.423973e-4
GO:0052200	response to host defenses	2.494593e-4
GO:0042503	tyrosine phosphorylation of Stat3 protein	2.503502e-4
GO:0045918	negative regulation of cytolysis	2.515915e-4
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.607233e-4
GO:0048569	post-embryonic organ development	2.642152e-4
GO:0048873	homeostasis of number of cells within a tissue	2.646193e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	2.742226e-4
GO:0061157	mRNA destabilization	2.742226e-4
GO:0043060	meiotic metaphase I plate congression	2.755799e-4
GO:0051324	prophase	2.783953e-4
GO:0001569	patterning of blood vessels	2.808703e-4
GO:0010872	regulation of cholesterol esterification	2.845856e-4
GO:0043983	histone H4-K12 acetylation	2.849631e-4
GO:0019226	transmission of nerve impulse	2.872664e-4
GO:0035308	negative regulation of protein dephosphorylation	2.931081e-4
GO:0051935	glutamate uptake involved in synaptic transmission	2.937607e-4
GO:2000273	positive regulation of receptor activity	2.957704e-4
GO:0010873	positive regulation of cholesterol esterification	2.974223e-4
GO:0015914	phospholipid transport	3.001904e-4
GO:0060020	Bergmann glial cell differentiation	3.038538e-4
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	3.053425e-4
GO:0061098	positive regulation of protein tyrosine kinase activity	3.141084e-4
GO:0046886	positive regulation of hormone biosynthetic process	3.173342e-4
GO:0001970	positive regulation of activation of membrane attack complex	3.186790e-4
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	3.296321e-4
GO:0032958	inositol phosphate biosynthetic process	3.355765e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	3.368609e-4
GO:0070345	negative regulation of fat cell proliferation	3.521718e-4
GO:0008050	female courtship behavior	3.521718e-4
GO:0042823	pyridoxal phosphate biosynthetic process	3.521718e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	3.559140e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.633378e-4
GO:0008298	intracellular mRNA localization	3.676896e-4
GO:2000370	positive regulation of clathrin-mediated endocytosis	3.710786e-4
GO:0032900	negative regulation of neurotrophin production	3.710786e-4
GO:0032244	positive regulation of nucleoside transport	3.710786e-4
GO:0032462	regulation of protein homooligomerization	3.732147e-4
GO:0007338	single fertilization	3.805929e-4
GO:0001654	eye development	3.846828e-4
GO:0003333	amino acid transmembrane transport	3.897767e-4
GO:0034389	lipid particle organization	3.950326e-4
GO:0001990	regulation of systemic arterial blood pressure by hormone	3.965293e-4
GO:0070483	detection of hypoxia	3.973934e-4
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	4.032777e-4
GO:0007161	calcium-independent cell-matrix adhesion	4.032777e-4
GO:0072236	metanephric loop of Henle development	4.040828e-4
GO:0072329	monocarboxylic acid catabolic process	4.056302e-4
GO:0050804	regulation of synaptic transmission	4.089790e-4
GO:0040040	thermosensory behavior	4.092167e-4
GO:0001503	ossification	4.104718e-4
GO:0006422	aspartyl-tRNA aminoacylation	4.169941e-4
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	4.226973e-4
GO:0071460	cellular response to cell-matrix adhesion	4.229404e-4
GO:0071312	cellular response to alkaloid	4.251770e-4
GO:0006105	succinate metabolic process	4.304918e-4
GO:0006303	double-strand break repair via nonhomologous end joining	4.331912e-4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.344030e-4
GO:0007339	binding of sperm to zona pellucida	4.465337e-4
GO:0033700	phospholipid efflux	4.492300e-4
GO:0001501	skeletal system development	4.508340e-4
GO:0051899	membrane depolarization	4.511175e-4
GO:0021523	somatic motor neuron differentiation	4.514978e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	4.547028e-4
GO:0042552	myelination	4.569812e-4
GO:0050764	regulation of phagocytosis	4.569957e-4
GO:0048871	multicellular organismal homeostasis	4.759293e-4
GO:0035524	proline transmembrane transport	4.807488e-4
GO:0035303	regulation of dephosphorylation	4.857445e-4
GO:0032800	receptor biosynthetic process	4.945970e-4
GO:0010669	epithelial structure maintenance	5.275958e-4
GO:0031017	exocrine pancreas development	5.291726e-4
GO:0048671	negative regulation of collateral sprouting	5.483069e-4
GO:0045936	negative regulation of phosphate metabolic process	5.602086e-4
GO:0046325	negative regulation of glucose import	5.654834e-4
GO:0050957	equilibrioception	5.696896e-4
GO:0045986	negative regulation of smooth muscle contraction	5.732237e-4
GO:0001843	neural tube closure	5.848691e-4
GO:0002885	positive regulation of hypersensitivity	5.942742e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	5.988649e-4
GO:0055012	ventricular cardiac muscle cell differentiation	6.084390e-4
GO:0051969	regulation of transmission of nerve impulse	6.114722e-4
GO:0009062	fatty acid catabolic process	6.163983e-4
GO:0045123	cellular extravasation	6.244986e-4
GO:0007184	SMAD protein import into nucleus	6.327971e-4
GO:0051797	regulation of hair follicle development	6.404165e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	6.505334e-4
GO:0030260	entry into host cell	6.565039e-4
GO:0006873	cellular ion homeostasis	6.623102e-4
GO:0072239	metanephric glomerulus vasculature development	6.839479e-4
GO:0044154	histone H3-K14 acetylation	7.039473e-4
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	7.310352e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	7.374390e-4
GO:0046512	sphingosine biosynthetic process	7.454277e-4
GO:2000210	positive regulation of anoikis	7.614568e-4
GO:0072089	stem cell proliferation	7.614568e-4
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	7.661665e-4
GO:0048703	embryonic viscerocranium morphogenesis	7.669857e-4
GO:0034766	negative regulation of ion transmembrane transport	7.674046e-4
GO:0042538	hyperosmotic salinity response	7.674241e-4
GO:0007621	negative regulation of female receptivity	7.674241e-4
GO:0014013	regulation of gliogenesis	7.774334e-4
GO:0030449	regulation of complement activation	7.788998e-4
GO:0050765	negative regulation of phagocytosis	7.910245e-4
GO:0014020	primary neural tube formation	8.091173e-4
GO:0035105	sterol regulatory element binding protein import into nucleus	8.092506e-4
GO:0032425	positive regulation of mismatch repair	8.092506e-4
GO:0050766	positive regulation of phagocytosis	8.242057e-4
GO:0051588	regulation of neurotransmitter transport	8.359510e-4
GO:0032928	regulation of superoxide anion generation	8.474692e-4
GO:0060606	tube closure	8.652621e-4
GO:0070489	T cell aggregation	8.760459e-4
GO:0031329	regulation of cellular catabolic process	8.889266e-4
GO:0055082	cellular chemical homeostasis	8.941947e-4
GO:0048568	embryonic organ development	9.132523e-4
GO:0050729	positive regulation of inflammatory response	9.184428e-4
GO:0007431	salivary gland development	9.372641e-4
GO:0072104	glomerular capillary formation	9.448152e-4
GO:0006268	DNA unwinding involved in replication	9.448152e-4
GO:0051932	synaptic transmission, GABAergic	9.576429e-4
GO:0032074	negative regulation of nuclease activity	9.576429e-4
GO:0060249	anatomical structure homeostasis	9.797063e-4
GO:0006670	sphingosine metabolic process	1.000651e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.006179e-3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.022564e-3
GO:0003062	regulation of heart rate by chemical signal	1.022564e-3
GO:0031063	regulation of histone deacetylation	1.057519e-3
GO:2000438	negative regulation of monocyte extravasation	1.068205e-3
GO:0080154	regulation of fertilization	1.068205e-3
GO:0035723	interleukin-15-mediated signaling pathway	1.068205e-3
GO:0035724	CD24 biosynthetic process	1.068205e-3
GO:0031915	positive regulation of synaptic plasticity	1.069658e-3
GO:0071731	response to nitric oxide	1.078559e-3
GO:0043966	histone H3 acetylation	1.094864e-3
GO:0035136	forelimb morphogenesis	1.094864e-3
GO:0015816	glycine transport	1.104537e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1.107593e-3
GO:0046426	negative regulation of JAK-STAT cascade	1.130820e-3
GO:0010172	embryonic body morphogenesis	1.139069e-3
GO:0032909	regulation of transforming growth factor beta2 production	1.167589e-3
GO:0032792	negative regulation of CREB transcription factor activity	1.168537e-3
GO:0072234	metanephric nephron tubule development	1.180482e-3
GO:0072488	ammonium transmembrane transport	1.185812e-3
GO:0042634	regulation of hair cycle	1.186742e-3
GO:0048010	vascular endothelial growth factor receptor signaling pathway	1.196978e-3
GO:0007128	meiotic prophase I	1.208296e-3
GO:0007626	locomotory behavior	1.210647e-3
GO:0030952	establishment or maintenance of cytoskeleton polarity	1.211357e-3
GO:0006012	galactose metabolic process	1.224486e-3
GO:0030902	hindbrain development	1.240109e-3
GO:0030166	proteoglycan biosynthetic process	1.240409e-3
GO:0043547	positive regulation of GTPase activity	1.248736e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.287364e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	1.291738e-3
GO:0035854	eosinophil fate commitment	1.297869e-3
GO:0030222	eosinophil differentiation	1.297869e-3
GO:0072355	histone H3-T3 phosphorylation	1.311598e-3
GO:0042780	tRNA 3'-end processing	1.311598e-3
GO:0070141	response to UV-A	1.331349e-3
GO:0032864	activation of Cdc42 GTPase activity	1.333874e-3
GO:0019087	transformation of host cell by virus	1.342194e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	1.348336e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.373946e-3
GO:0048592	eye morphogenesis	1.378026e-3
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.443806e-3
GO:0007402	ganglion mother cell fate determination	1.464831e-3
GO:0006657	CDP-choline pathway	1.476406e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.516215e-3
GO:0040020	regulation of meiosis	1.552238e-3
GO:0008366	axon ensheathment	1.567070e-3
GO:0048593	camera-type eye morphogenesis	1.573171e-3
GO:0046588	negative regulation of calcium-dependent cell-cell adhesion	1.623105e-3
GO:0051890	regulation of cardioblast differentiation	1.629375e-3
GO:0050773	regulation of dendrite development	1.636743e-3
GO:0051005	negative regulation of lipoprotein lipase activity	1.636867e-3
GO:2000346	negative regulation of hepatocyte proliferation	1.702271e-3
GO:2000639	negative regulation of SREBP-mediated signaling pathway	1.702271e-3
GO:0046208	spermine catabolic process	1.706033e-3
GO:0043117	positive regulation of vascular permeability	1.740462e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.743659e-3
GO:0072054	renal outer medulla development	1.760115e-3
GO:0072053	renal inner medulla development	1.760115e-3
GO:0045143	homologous chromosome segregation	1.763469e-3
GO:0007156	homophilic cell adhesion	1.771981e-3
GO:0045116	protein neddylation	1.792393e-3
GO:0060896	neural plate pattern specification	1.799626e-3
GO:0060710	chorio-allantoic fusion	1.814576e-3
GO:0060221	retinal rod cell differentiation	1.818505e-3
GO:0070255	regulation of mucus secretion	1.818505e-3
GO:0043932	ossification involved in bone remodeling	1.875720e-3
GO:0009792	embryo development ending in birth or egg hatching	1.898923e-3
GO:2000744	positive regulation of anterior head development	1.912019e-3
GO:0060018	astrocyte fate commitment	1.945914e-3
GO:0045807	positive regulation of endocytosis	1.989434e-3
GO:0010954	positive regulation of protein processing	1.989866e-3
GO:0046520	sphingoid biosynthetic process	1.996238e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	2.011284e-3
GO:0072080	nephron tubule development	2.051187e-3
GO:0050886	endocrine process	2.099449e-3
GO:0002637	regulation of immunoglobulin production	2.103424e-3
GO:0043009	chordate embryonic development	2.108952e-3
GO:0071453	cellular response to oxygen levels	2.111495e-3
GO:0072170	metanephric tubule development	2.116843e-3
GO:0006706	steroid catabolic process	2.120281e-3
GO:0045924	regulation of female receptivity	2.150978e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	2.194894e-3
GO:0072181	mesonephric duct formation	2.208000e-3
GO:0070672	response to interleukin-15	2.215097e-3
GO:0021569	rhombomere 3 development	2.215097e-3
GO:0060215	primitive hemopoiesis	2.248271e-3
GO:0060976	coronary vasculature development	2.253561e-3
GO:0010889	regulation of sequestering of triglyceride	2.253561e-3
GO:0007389	pattern specification process	2.255641e-3
GO:0000726	non-recombinational repair	2.272007e-3
GO:0060973	cell migration involved in heart development	2.275577e-3
GO:0003218	cardiac left ventricle formation	2.321920e-3
GO:0021533	cell differentiation in hindbrain	2.331371e-3
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	2.343206e-3
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	2.343206e-3
GO:0030277	maintenance of gastrointestinal epithelium	2.368286e-3
GO:0048702	embryonic neurocranium morphogenesis	2.380856e-3
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	2.395682e-3
GO:0030037	actin filament reorganization involved in cell cycle	2.397247e-3
GO:0016064	immunoglobulin mediated immune response	2.406660e-3
GO:0033120	positive regulation of RNA splicing	2.419741e-3
GO:0060040	retinal bipolar neuron differentiation	2.422793e-3
GO:0031065	positive regulation of histone deacetylation	2.438545e-3
GO:0048745	smooth muscle tissue development	2.463698e-3
GO:0071593	lymphocyte aggregation	2.475070e-3
GO:0033057	multicellular organismal reproductive behavior	2.502396e-3
GO:0045663	positive regulation of myoblast differentiation	2.507656e-3
GO:0060350	endochondral bone morphogenesis	2.584633e-3
GO:0048634	regulation of muscle organ development	2.594532e-3
GO:0060980	cell migration involved in coronary vasculogenesis	2.632187e-3
GO:0070555	response to interleukin-1	2.641871e-3
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	2.689981e-3
GO:0045637	regulation of myeloid cell differentiation	2.703271e-3
GO:0021797	forebrain anterior/posterior pattern specification	2.706935e-3
GO:0001666	response to hypoxia	2.744549e-3
GO:0019725	cellular homeostasis	2.756611e-3
GO:0060133	somatotropin secreting cell development	2.765426e-3
GO:0001974	blood vessel remodeling	2.779751e-3
GO:0031099	regeneration	2.796024e-3
GO:0016075	rRNA catabolic process	2.823139e-3
GO:0060047	heart contraction	2.898128e-3
GO:0061046	regulation of branching involved in lung morphogenesis	2.916134e-3
GO:0035295	tube development	2.920707e-3
GO:0019233	sensory perception of pain	3.034451e-3
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	3.038199e-3
GO:0031022	nuclear migration along microfilament	3.084800e-3
GO:0018208	peptidyl-proline modification	3.095386e-3
GO:0045657	positive regulation of monocyte differentiation	3.106126e-3
GO:0002076	osteoblast development	3.115976e-3
GO:0021702	cerebellar Purkinje cell differentiation	3.143067e-3
GO:0030823	regulation of cGMP metabolic process	3.194309e-3
GO:0090193	positive regulation of glomerulus development	3.225540e-3
GO:0021547	midbrain-hindbrain boundary initiation	3.241125e-3
GO:0021501	prechordal plate formation	3.241125e-3
GO:0042297	vocal learning	3.260443e-3
GO:0034227	tRNA thio-modification	3.260443e-3
GO:0002098	tRNA wobble uridine modification	3.260443e-3
GO:0043010	camera-type eye development	3.267359e-3
GO:0060466	activation of meiosis involved in egg activation	3.279545e-3
GO:0044130	negative regulation of growth of symbiont in host	3.300626e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0030488	tRNA methylation	1.121286e-15
GO:0010565	regulation of cellular ketone metabolic process	2.354649e-12
GO:0042304	regulation of fatty acid biosynthetic process	1.467479e-11
GO:0051049	regulation of transport	1.526393e-11
GO:0043269	regulation of ion transport	8.563847e-10
GO:0009895	negative regulation of catabolic process	1.732906e-9
GO:0060341	regulation of cellular localization	3.118345e-9
GO:0070588	calcium ion transmembrane transport	3.154181e-9
GO:0072595	maintenance of protein localization to organelle	3.452567e-9
GO:0019217	regulation of fatty acid metabolic process	5.347112e-9
GO:0033238	regulation of cellular amine metabolic process	6.807600e-9
GO:0031330	negative regulation of cellular catabolic process	8.904047e-9
GO:0050995	negative regulation of lipid catabolic process	9.322636e-9
GO:0006081	cellular aldehyde metabolic process	1.016406e-8
GO:0003008	system process	1.242722e-8
GO:0033700	phospholipid efflux	1.258294e-8
GO:0032369	negative regulation of lipid transport	1.490925e-8
GO:0006400	tRNA modification	1.532504e-8
GO:0046092	deoxycytidine metabolic process	1.570220e-8
GO:0034762	regulation of transmembrane transport	1.768362e-8
GO:0050994	regulation of lipid catabolic process	1.976295e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.585118e-8
GO:0034382	chylomicron remnant clearance	3.751707e-8
GO:0051457	maintenance of protein location in nucleus	4.064424e-8
GO:0010985	negative regulation of lipoprotein particle clearance	4.840275e-8
GO:0032368	regulation of lipid transport	5.184579e-8
GO:0045723	positive regulation of fatty acid biosynthetic process	5.628950e-8
GO:0001510	RNA methylation	5.669007e-8
GO:0051924	regulation of calcium ion transport	6.414978e-8
GO:0007586	digestion	1.252322e-7
GO:0045923	positive regulation of fatty acid metabolic process	1.928747e-7
GO:0008033	tRNA processing	2.085625e-7
GO:0010984	regulation of lipoprotein particle clearance	2.304442e-7
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2.422321e-7
GO:0071529	cementum mineralization	3.392142e-7
GO:0046184	aldehyde biosynthetic process	3.442618e-7
GO:0034765	regulation of ion transmembrane transport	3.564012e-7
GO:0051046	regulation of secretion	3.819695e-7
GO:0006942	regulation of striated muscle contraction	4.839396e-7
GO:0051047	positive regulation of secretion	4.844764e-7
GO:0009185	ribonucleoside diphosphate metabolic process	6.729437e-7
GO:0046501	protoporphyrinogen IX metabolic process	1.019947e-6
GO:0043932	ossification involved in bone remodeling	1.032255e-6
GO:0010522	regulation of calcium ion transport into cytosol	1.312481e-6
GO:0032502	developmental process	1.581503e-6
GO:0016074	snoRNA metabolic process	1.584135e-6
GO:0010936	negative regulation of macrophage cytokine production	1.686904e-6
GO:0010959	regulation of metal ion transport	1.696245e-6
GO:0045922	negative regulation of fatty acid metabolic process	1.714262e-6
GO:0023052	signaling	1.723258e-6
GO:0071456	cellular response to hypoxia	1.838332e-6
GO:0030819	positive regulation of cAMP biosynthetic process	1.947923e-6
GO:0035249	synaptic transmission, glutamatergic	2.159352e-6
GO:0015780	nucleotide-sugar transport	2.277635e-6
GO:0002407	dendritic cell chemotaxis	2.439502e-6
GO:0030801	positive regulation of cyclic nucleotide metabolic process	2.457890e-6
GO:0055117	regulation of cardiac muscle contraction	2.685103e-6
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	2.884202e-6
GO:0009132	nucleoside diphosphate metabolic process	3.036715e-6
GO:0033002	muscle cell proliferation	3.115856e-6
GO:0007154	cell communication	3.257471e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.681422e-6
GO:0018022	peptidyl-lysine methylation	3.681422e-6
GO:0009125	nucleoside monophosphate catabolic process	3.746112e-6
GO:0032375	negative regulation of cholesterol transport	4.103754e-6
GO:0018192	enzyme active site formation via L-cysteine persulfide	4.226701e-6
GO:0006117	acetaldehyde metabolic process	4.272019e-6
GO:0021670	lateral ventricle development	4.469951e-6
GO:0060338	regulation of type I interferon-mediated signaling pathway	4.484745e-6
GO:2000021	regulation of ion homeostasis	4.561393e-6
GO:0050789	regulation of biological process	4.919442e-6
GO:0065005	protein-lipid complex assembly	5.291356e-6
GO:0046939	nucleotide phosphorylation	5.453145e-6
GO:0045806	negative regulation of endocytosis	5.718461e-6
GO:0010676	positive regulation of cellular carbohydrate metabolic process	5.960170e-6
GO:0046889	positive regulation of lipid biosynthetic process	5.988925e-6
GO:0045576	mast cell activation	6.057388e-6
GO:0030855	epithelial cell differentiation	6.156476e-6
GO:0032501	multicellular organismal process	6.179843e-6
GO:0031000	response to caffeine	6.443586e-6
GO:0043279	response to alkaloid	6.453786e-6
GO:0051279	regulation of release of sequestered calcium ion into cytosol	6.482442e-6
GO:0071248	cellular response to metal ion	6.574626e-6
GO:0051005	negative regulation of lipoprotein lipase activity	6.743154e-6
GO:0010907	positive regulation of glucose metabolic process	6.966010e-6
GO:0045834	positive regulation of lipid metabolic process	7.848993e-6
GO:0032374	regulation of cholesterol transport	7.910516e-6
GO:0032891	negative regulation of organic acid transport	8.688812e-6
GO:0021591	ventricular system development	8.715943e-6
GO:0031536	positive regulation of exit from mitosis	8.858496e-6
GO:0070482	response to oxygen levels	8.893943e-6
GO:0060696	regulation of phospholipid catabolic process	9.185924e-6
GO:0010452	histone H3-K36 methylation	9.847502e-6
GO:0010900	negative regulation of phosphatidylcholine catabolic process	9.889531e-6
GO:0045598	regulation of fat cell differentiation	1.044527e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	1.076068e-5
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.170012e-5
GO:0071453	cellular response to oxygen levels	1.186469e-5
GO:0050708	regulation of protein secretion	1.270920e-5
GO:0034220	ion transmembrane transport	1.461678e-5
GO:0044057	regulation of system process	1.473890e-5
GO:0032409	regulation of transporter activity	1.534587e-5
GO:0009134	nucleoside diphosphate catabolic process	1.574179e-5
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.722961e-5
GO:0032655	regulation of interleukin-12 production	1.818106e-5
GO:0007270	neuron-neuron synaptic transmission	1.850160e-5
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	1.883653e-5
GO:0042559	pteridine-containing compound biosynthetic process	1.909502e-5
GO:0051901	positive regulation of mitochondrial depolarization	2.003001e-5
GO:0003254	regulation of membrane depolarization	2.013707e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.130392e-5
GO:0010897	negative regulation of triglyceride catabolic process	2.130392e-5
GO:0030300	regulation of intestinal cholesterol absorption	2.156723e-5
GO:0031326	regulation of cellular biosynthetic process	2.228238e-5
GO:0065007	biological regulation	2.310196e-5
GO:0045055	regulated secretory pathway	2.313997e-5
GO:0080090	regulation of primary metabolic process	2.324563e-5
GO:0007613	memory	2.361270e-5
GO:0009817	defense response to fungus, incompatible interaction	2.424610e-5
GO:0009214	cyclic nucleotide catabolic process	2.537600e-5
GO:0032412	regulation of ion transmembrane transporter activity	2.542665e-5
GO:0031327	negative regulation of cellular biosynthetic process	2.590337e-5
GO:0051239	regulation of multicellular organismal process	2.634587e-5
GO:0009191	ribonucleoside diphosphate catabolic process	2.643993e-5
GO:0071496	cellular response to external stimulus	2.709658e-5
GO:0009636	response to toxin	2.718820e-5
GO:0050880	regulation of blood vessel size	2.737332e-5
GO:0032879	regulation of localization	2.765462e-5
GO:0055085	transmembrane transport	3.018142e-5
GO:0006376	mRNA splice site selection	3.021456e-5
GO:0003018	vascular process in circulatory system	3.029545e-5
GO:0035150	regulation of tube size	3.045574e-5
GO:0016579	protein deubiquitination	3.047339e-5
GO:0001666	response to hypoxia	3.147596e-5
GO:0042249	establishment of planar polarity of embryonic epithelium	3.227112e-5
GO:0042311	vasodilation	3.353087e-5
GO:0051764	actin crosslink formation	3.372397e-5
GO:0009890	negative regulation of biosynthetic process	3.392577e-5
GO:0048731	system development	3.413041e-5
GO:0006779	porphyrin-containing compound biosynthetic process	3.469427e-5
GO:0055017	cardiac muscle tissue growth	3.487384e-5
GO:0006399	tRNA metabolic process	3.703058e-5
GO:0046330	positive regulation of JNK cascade	3.706758e-5
GO:0042177	negative regulation of protein catabolic process	3.715275e-5
GO:0048261	negative regulation of receptor-mediated endocytosis	3.751957e-5
GO:0009892	negative regulation of metabolic process	3.803331e-5
GO:0051099	positive regulation of binding	3.987385e-5
GO:0050794	regulation of cellular process	4.002530e-5
GO:0019438	aromatic compound biosynthetic process	4.230415e-5
GO:0014034	neural crest cell fate commitment	4.552845e-5
GO:0060079	regulation of excitatory postsynaptic membrane potential	4.559019e-5
GO:0015862	uridine transport	4.586718e-5
GO:0001832	blastocyst growth	4.642790e-5
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	4.806715e-5
GO:0044241	lipid digestion	4.820167e-5
GO:0017157	regulation of exocytosis	4.924624e-5
GO:0043691	reverse cholesterol transport	5.037223e-5
GO:0032488	Cdc42 protein signal transduction	5.273483e-5
GO:0009396	folic acid-containing compound biosynthetic process	5.381556e-5
GO:0001539	ciliary or flagellar motility	5.546511e-5
GO:0043587	tongue morphogenesis	5.739499e-5
GO:0002739	regulation of cytokine secretion involved in immune response	5.739499e-5
GO:0006109	regulation of carbohydrate metabolic process	5.787410e-5
GO:0031323	regulation of cellular metabolic process	5.794404e-5
GO:0060627	regulation of vesicle-mediated transport	5.873155e-5
GO:0050714	positive regulation of protein secretion	5.877954e-5
GO:0035725	sodium ion transmembrane transport	5.903171e-5
GO:0007275	multicellular organismal development	5.908620e-5
GO:0046890	regulation of lipid biosynthetic process	5.991017e-5
GO:0007165	signal transduction	6.079425e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	6.079430e-5
GO:0035887	aortic smooth muscle cell differentiation	6.079430e-5
GO:0014074	response to purine-containing compound	6.203745e-5
GO:0015864	pyrimidine nucleoside transport	6.315947e-5
GO:0050916	sensory perception of sweet taste	6.660725e-5
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	6.784859e-5
GO:0010873	positive regulation of cholesterol esterification	6.826219e-5
GO:0072531	pyrimidine-containing compound transmembrane transport	7.000712e-5
GO:0043303	mast cell degranulation	7.006319e-5
GO:0010675	regulation of cellular carbohydrate metabolic process	7.550870e-5
GO:0009451	RNA modification	7.559826e-5
GO:0032965	regulation of collagen biosynthetic process	7.571374e-5
GO:0033013	tetrapyrrole metabolic process	7.640130e-5
GO:0009889	regulation of biosynthetic process	7.756759e-5
GO:0043653	mitochondrial fragmentation involved in apoptosis	7.813213e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	7.824738e-5
GO:0008156	negative regulation of DNA replication	7.869582e-5
GO:0046031	ADP metabolic process	7.908986e-5
GO:0022898	regulation of transmembrane transporter activity	8.349471e-5
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	8.837393e-5
GO:0045722	positive regulation of gluconeogenesis	8.837393e-5
GO:0002718	regulation of cytokine production involved in immune response	8.863535e-5
GO:0006778	porphyrin-containing compound metabolic process	8.909393e-5
GO:0043299	leukocyte degranulation	9.325870e-5
GO:0071169	establishment of protein localization to chromatin	9.347612e-5
GO:0035865	cellular response to potassium ion	9.347612e-5
GO:0019047	provirus integration	9.347612e-5
GO:0034651	cortisol biosynthetic process	9.347612e-5
GO:0045601	regulation of endothelial cell differentiation	9.492020e-5
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	9.592615e-5
GO:0044240	multicellular organismal lipid catabolic process	9.909567e-5
GO:2000300	regulation of synaptic vesicle exocytosis	1.006385e-4
GO:0031328	positive regulation of cellular biosynthetic process	1.006442e-4
GO:0009891	positive regulation of biosynthetic process	1.056861e-4
GO:0051171	regulation of nitrogen compound metabolic process	1.061796e-4
GO:0045074	regulation of interleukin-10 biosynthetic process	1.067885e-4
GO:0007610	behavior	1.091992e-4
GO:0007422	peripheral nervous system development	1.108849e-4
GO:0090257	regulation of muscle system process	1.136719e-4
GO:0051051	negative regulation of transport	1.145560e-4
GO:0015824	proline transport	1.145755e-4
GO:0035524	proline transmembrane transport	1.150351e-4
GO:0046341	CDP-diacylglycerol metabolic process	1.164789e-4
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	1.164789e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.164789e-4
GO:0015684	ferrous iron transport	1.186406e-4
GO:0070201	regulation of establishment of protein localization	1.203223e-4
GO:0019722	calcium-mediated signaling	1.234283e-4
GO:0010906	regulation of glucose metabolic process	1.237986e-4
GO:0070328	triglyceride homeostasis	1.254644e-4
GO:0009894	regulation of catabolic process	1.291043e-4
GO:0071407	cellular response to organic cyclic compound	1.297252e-4
GO:0006739	NADP metabolic process	1.317983e-4
GO:0014037	Schwann cell differentiation	1.319944e-4
GO:0048856	anatomical structure development	1.327895e-4
GO:0030799	regulation of cyclic nucleotide metabolic process	1.372367e-4
GO:0018026	peptidyl-lysine monomethylation	1.375831e-4
GO:0043414	macromolecule methylation	1.428738e-4
GO:0032967	positive regulation of collagen biosynthetic process	1.437296e-4
GO:0031324	negative regulation of cellular metabolic process	1.466934e-4
GO:2000191	regulation of fatty acid transport	1.481121e-4
GO:0043255	regulation of carbohydrate biosynthetic process	1.481834e-4
GO:0002274	myeloid leukocyte activation	1.505424e-4
GO:0060419	heart growth	1.535564e-4
GO:0014070	response to organic cyclic compound	1.565916e-4
GO:0070483	detection of hypoxia	1.643555e-4
GO:0010633	negative regulation of epithelial cell migration	1.687072e-4
GO:0002444	myeloid leukocyte mediated immunity	1.721929e-4
GO:0021592	fourth ventricle development	1.755546e-4
GO:0030154	cell differentiation	1.764730e-4
GO:0045940	positive regulation of steroid metabolic process	1.768755e-4
GO:0042255	ribosome assembly	1.793762e-4
GO:0046186	acetaldehyde biosynthetic process	1.887272e-4
GO:0044342	type B pancreatic cell proliferation	1.887272e-4
GO:0055015	ventricular cardiac muscle cell development	1.924637e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.937677e-4
GO:0001817	regulation of cytokine production	1.949918e-4
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.952036e-4
GO:0031329	regulation of cellular catabolic process	1.975099e-4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	2.010657e-4
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	2.046535e-4
GO:0048869	cellular developmental process	2.060724e-4
GO:0031914	negative regulation of synaptic plasticity	2.090721e-4
GO:0003032	detection of oxygen	2.107990e-4
GO:0014051	gamma-aminobutyric acid secretion	2.126970e-4
GO:0046373	L-arabinose metabolic process	2.193030e-4
GO:0000238	zygotene	2.193030e-4
GO:0010721	negative regulation of cell development	2.224029e-4
GO:0010872	regulation of cholesterol esterification	2.259334e-4
GO:0045082	positive regulation of interleukin-10 biosynthetic process	2.271044e-4
GO:0007096	regulation of exit from mitosis	2.271044e-4
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	2.279691e-4
GO:0007611	learning or memory	2.286234e-4
GO:0060347	heart trabecula formation	2.315182e-4
GO:0016539	intein-mediated protein splicing	2.341651e-4
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	2.388699e-4
GO:0032933	SREBP-mediated signaling pathway	2.487331e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.487331e-4
GO:0042482	positive regulation of odontogenesis	2.521882e-4
GO:0045906	negative regulation of vasoconstriction	2.544888e-4
GO:0033344	cholesterol efflux	2.587577e-4
GO:0003012	muscle system process	2.589037e-4
GO:0071773	cellular response to BMP stimulus	2.627352e-4
GO:0060620	regulation of cholesterol import	2.627352e-4
GO:0040007	growth	2.807709e-4
GO:0044058	regulation of digestive system process	2.959688e-4
GO:0002507	tolerance induction	2.969141e-4
GO:0070646	protein modification by small protein removal	3.111402e-4
GO:0017085	response to insecticide	3.161279e-4
GO:0061001	regulation of dendritic spine morphogenesis	3.200465e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	3.210673e-4
GO:0006241	CTP biosynthetic process	3.215499e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.302094e-4
GO:0051930	regulation of sensory perception of pain	3.312582e-4
GO:0006959	humoral immune response	3.416625e-4
GO:0001833	inner cell mass cell proliferation	3.419136e-4
GO:0003229	ventricular cardiac muscle tissue development	3.461405e-4
GO:0046293	formaldehyde biosynthetic process	3.518406e-4
GO:0007202	activation of phospholipase C activity	3.529026e-4
GO:0033136	serine phosphorylation of STAT3 protein	3.550341e-4
GO:0042035	regulation of cytokine biosynthetic process	3.558502e-4
GO:0001649	osteoblast differentiation	3.562098e-4
GO:0010595	positive regulation of endothelial cell migration	3.637269e-4
GO:0003009	skeletal muscle contraction	3.718384e-4
GO:0033363	secretory granule organization	3.721488e-4
GO:0033205	cell cycle cytokinesis	3.784178e-4
GO:0042755	eating behavior	3.789607e-4
GO:0010896	regulation of triglyceride catabolic process	3.806858e-4
GO:0061337	cardiac conduction	3.814269e-4
GO:0060038	cardiac muscle cell proliferation	3.814269e-4
GO:0000045	autophagic vacuole assembly	3.833869e-4
GO:0070584	mitochondrion morphogenesis	3.860418e-4
GO:0045833	negative regulation of lipid metabolic process	3.867080e-4
GO:0006937	regulation of muscle contraction	3.883893e-4
GO:0034101	erythrocyte homeostasis	4.002665e-4
GO:0030814	regulation of cAMP metabolic process	4.006584e-4
GO:0010863	positive regulation of phospholipase C activity	4.034051e-4
GO:0010605	negative regulation of macromolecule metabolic process	4.059706e-4
GO:0010629	negative regulation of gene expression	4.068277e-4
GO:0006198	cAMP catabolic process	4.068835e-4
GO:0031644	regulation of neurological system process	4.133001e-4
GO:0030817	regulation of cAMP biosynthetic process	4.236764e-4
GO:0071241	cellular response to inorganic substance	4.332910e-4
GO:0030431	sleep	4.357944e-4
GO:0032099	negative regulation of appetite	4.424476e-4
GO:0060621	negative regulation of cholesterol import	4.477829e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	4.499304e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.499310e-4
GO:0060192	negative regulation of lipase activity	4.633649e-4
GO:0045600	positive regulation of fat cell differentiation	4.723592e-4
GO:0008286	insulin receptor signaling pathway	4.864410e-4
GO:0050890	cognition	4.965400e-4
GO:0009201	ribonucleoside triphosphate biosynthetic process	5.013184e-4
GO:0045368	positive regulation of interleukin-13 biosynthetic process	5.037742e-4
GO:0006982	response to lipid hydroperoxide	5.037742e-4
GO:0070875	positive regulation of glycogen metabolic process	5.047990e-4
GO:0034699	response to luteinizing hormone stimulus	5.076694e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	5.076694e-4
GO:0042558	pteridine-containing compound metabolic process	5.123050e-4
GO:0035235	ionotropic glutamate receptor signaling pathway	5.126984e-4
GO:0065009	regulation of molecular function	5.292367e-4
GO:0060078	regulation of postsynaptic membrane potential	5.391094e-4
GO:0043687	post-translational protein modification	5.411717e-4
GO:0034695	response to prostaglandin E stimulus	5.411717e-4
GO:0070169	positive regulation of biomineral tissue development	5.442571e-4
GO:0009142	nucleoside triphosphate biosynthetic process	5.557725e-4
GO:0048343	paraxial mesodermal cell fate commitment	5.594953e-4
GO:0000245	spliceosome assembly	5.610641e-4
GO:0048143	astrocyte activation	5.660134e-4
GO:0060193	positive regulation of lipase activity	5.664806e-4
GO:0008615	pyridoxine biosynthetic process	5.837280e-4
GO:0006930	substrate-dependent cell migration, cell extension	5.837280e-4
GO:0060281	regulation of oocyte development	5.852076e-4
GO:0060282	positive regulation of oocyte development	5.852076e-4
GO:0048167	regulation of synaptic plasticity	5.923046e-4
GO:0032096	negative regulation of response to food	6.018095e-4
GO:0051533	positive regulation of NFAT protein import into nucleus	6.050864e-4
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.183262e-4
GO:0044246	regulation of multicellular organismal metabolic process	6.196546e-4
GO:0030802	regulation of cyclic nucleotide biosynthetic process	6.306209e-4
GO:0051223	regulation of protein transport	6.512814e-4
GO:0034633	retinol transport	6.528227e-4
GO:0071622	regulation of granulocyte chemotaxis	6.552894e-4
GO:0033239	negative regulation of cellular amine metabolic process	6.558015e-4
GO:0021678	third ventricle development	6.578542e-4
GO:0050713	negative regulation of interleukin-1 beta secretion	6.578542e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	6.596487e-4
GO:0050877	neurological system process	6.651607e-4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	6.669871e-4
GO:0051241	negative regulation of multicellular organismal process	6.728547e-4
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	6.739763e-4
GO:0051489	regulation of filopodium assembly	6.740589e-4
GO:0006816	calcium ion transport	6.817237e-4
GO:0051403	stress-activated MAPK cascade	6.998185e-4
GO:0051586	positive regulation of dopamine uptake	7.050966e-4
GO:0019682	glyceraldehyde-3-phosphate metabolic process	7.050966e-4
GO:0006936	muscle contraction	7.211634e-4
GO:0051900	regulation of mitochondrial depolarization	7.224242e-4
GO:0007184	SMAD protein import into nucleus	7.260640e-4
GO:0007517	muscle organ development	7.274290e-4
GO:0048259	regulation of receptor-mediated endocytosis	7.401228e-4
GO:0070838	divalent metal ion transport	7.590951e-4
GO:0055010	ventricular cardiac muscle tissue morphogenesis	7.679293e-4
GO:0050849	negative regulation of calcium-mediated signaling	7.877603e-4
GO:0048659	smooth muscle cell proliferation	7.882282e-4
GO:0090037	positive regulation of protein kinase C signaling cascade	7.918441e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	8.095466e-4
GO:0044093	positive regulation of molecular function	8.246572e-4
GO:0016126	sterol biosynthetic process	8.334574e-4
GO:0052200	response to host defenses	8.386646e-4
GO:0031668	cellular response to extracellular stimulus	8.431973e-4
GO:0002675	positive regulation of acute inflammatory response	8.675686e-4
GO:0015804	neutral amino acid transport	8.709052e-4
GO:0014916	regulation of lung blood pressure	8.731393e-4
GO:0006695	cholesterol biosynthetic process	8.758097e-4
GO:0007181	transforming growth factor beta receptor complex assembly	8.821219e-4
GO:0090086	negative regulation of protein deubiquitination	8.821219e-4
GO:0003094	glomerular filtration	8.821219e-4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	8.952431e-4
GO:0034504	protein localization to nucleus	9.121993e-4
GO:0090209	negative regulation of triglyceride metabolic process	9.204542e-4
GO:0033240	positive regulation of cellular amine metabolic process	9.204542e-4
GO:0060491	regulation of cell projection assembly	9.427402e-4
GO:0003013	circulatory system process	9.465611e-4
GO:0034377	plasma lipoprotein particle assembly	9.560150e-4
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	9.560150e-4
GO:0050804	regulation of synaptic transmission	9.979755e-4
GO:0060998	regulation of dendritic spine development	1.000978e-3
GO:0018023	peptidyl-lysine trimethylation	1.014958e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	1.034423e-3
GO:0006098	pentose-phosphate shunt	1.044197e-3
GO:0009145	purine nucleoside triphosphate biosynthetic process	1.066457e-3
GO:0046321	positive regulation of fatty acid oxidation	1.069976e-3
GO:0031998	regulation of fatty acid beta-oxidation	1.089804e-3
GO:0072511	divalent inorganic cation transport	1.090501e-3
GO:0006481	C-terminal protein methylation	1.092397e-3
GO:0035269	protein O-linked mannosylation	1.092397e-3
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.107426e-3
GO:0006704	glucocorticoid biosynthetic process	1.107721e-3
GO:0048518	positive regulation of biological process	1.110682e-3
GO:0060124	positive regulation of growth hormone secretion	1.124320e-3
GO:2000377	regulation of reactive oxygen species metabolic process	1.132417e-3
GO:0051098	regulation of binding	1.137982e-3
GO:0007399	nervous system development	1.175193e-3
GO:0009893	positive regulation of metabolic process	1.196715e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.200864e-3
GO:0007386	compartment pattern specification	1.238633e-3
GO:0018027	peptidyl-lysine dimethylation	1.238668e-3
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	1.267255e-3
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	1.267255e-3
GO:2000664	positive regulation of interleukin-5 secretion	1.267255e-3
GO:2000667	positive regulation of interleukin-13 secretion	1.267255e-3
GO:0001806	type IV hypersensitivity	1.267255e-3
GO:0060374	mast cell differentiation	1.267255e-3
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	1.267255e-3
GO:0044253	positive regulation of multicellular organismal metabolic process	1.276719e-3
GO:0072220	metanephric descending thin limb development	1.324283e-3
GO:0072230	metanephric proximal straight tubule development	1.324283e-3
GO:0072232	metanephric proximal convoluted tubule segment 2 development	1.324283e-3
GO:0051458	corticotropin secretion	1.324283e-3
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	1.324283e-3
GO:0035378	carbon dioxide transmembrane transport	1.324283e-3
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.324283e-3
GO:0016142	O-glycoside catabolic process	1.324283e-3
GO:0035377	transepithelial water transport	1.324283e-3
GO:0034447	very-low-density lipoprotein particle clearance	1.342144e-3
GO:0044030	regulation of DNA methylation	1.355324e-3
GO:0043113	receptor clustering	1.364062e-3
GO:0045603	positive regulation of endothelial cell differentiation	1.372387e-3
GO:0048644	muscle organ morphogenesis	1.383922e-3
GO:0071277	cellular response to calcium ion	1.412236e-3
GO:0050709	negative regulation of protein secretion	1.459569e-3
GO:0060155	platelet dense granule organization	1.471678e-3
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	1.471678e-3
GO:0001867	complement activation, lectin pathway	1.473030e-3
GO:0034380	high-density lipoprotein particle assembly	1.497121e-3
GO:0032526	response to retinoic acid	1.504031e-3
GO:0050765	negative regulation of phagocytosis	1.505795e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.506993e-3
GO:0001503	ossification	1.515802e-3
GO:0043583	ear development	1.516588e-3
GO:0051135	positive regulation of NK T cell activation	1.526085e-3
GO:0061098	positive regulation of protein tyrosine kinase activity	1.562429e-3
GO:0048738	cardiac muscle tissue development	1.570209e-3
GO:0006756	AMP phosphorylation	1.591035e-3
GO:0050823	peptide antigen stabilization	1.591035e-3
GO:0032342	aldosterone biosynthetic process	1.591035e-3
GO:0002897	positive regulation of central B cell tolerance induction	1.591035e-3
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.591035e-3
GO:0002508	central tolerance induction	1.591035e-3
GO:0030501	positive regulation of bone mineralization	1.636363e-3
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	1.642399e-3
GO:0007267	cell-cell signaling	1.650281e-3
GO:0061035	regulation of cartilage development	1.657488e-3
GO:0046415	urate metabolic process	1.669201e-3
GO:0001969	regulation of activation of membrane attack complex	1.669748e-3
GO:0018193	peptidyl-amino acid modification	1.682612e-3
GO:0032649	regulation of interferon-gamma production	1.686818e-3
GO:0050771	negative regulation of axonogenesis	1.688469e-3
GO:0032615	interleukin-12 production	1.722193e-3
GO:0071205	protein localization to juxtaparanode region of axon	1.722193e-3
GO:0048535	lymph node development	1.724416e-3
GO:0019222	regulation of metabolic process	1.728374e-3
GO:0048144	fibroblast proliferation	1.744708e-3
GO:0031325	positive regulation of cellular metabolic process	1.780037e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.807271e-3
GO:0051050	positive regulation of transport	1.834737e-3
GO:0003015	heart process	1.851583e-3
GO:0008625	induction of apoptosis via death domain receptors	1.851635e-3
GO:0010887	negative regulation of cholesterol storage	1.872885e-3
GO:0060976	coronary vasculature development	1.878357e-3
GO:0032863	activation of Rac GTPase activity	1.897539e-3
GO:0010954	positive regulation of protein processing	1.897539e-3
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.897539e-3
GO:0009236	cobalamin biosynthetic process	1.902027e-3
GO:0033120	positive regulation of RNA splicing	1.911061e-3
GO:0032000	positive regulation of fatty acid beta-oxidation	1.918977e-3
GO:0046320	regulation of fatty acid oxidation	1.928883e-3
GO:0006111	regulation of gluconeogenesis	1.988903e-3
GO:0046928	regulation of neurotransmitter secretion	1.995695e-3
GO:0045725	positive regulation of glycogen biosynthetic process	2.047899e-3
GO:0051899	membrane depolarization	2.052164e-3
GO:0001970	positive regulation of activation of membrane attack complex	2.073737e-3
GO:0007440	foregut morphogenesis	2.125118e-3
GO:0042823	pyridoxal phosphate biosynthetic process	2.135198e-3
GO:0031508	centromeric heterochromatin formation	2.135198e-3
GO:0032890	regulation of organic acid transport	2.147066e-3
GO:0050729	positive regulation of inflammatory response	2.153247e-3
GO:0048016	inositol phosphate-mediated signaling	2.189572e-3
GO:0050881	musculoskeletal movement	2.196139e-3