Novel motif:47

name:	motif47_CGAGTN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0005981	regulation of glycogen catabolic process	2.747538e-11
GO:0071585	detoxification of cadmium ion	8.379217e-10
GO:0034470	ncRNA processing	1.093058e-8
GO:0090281	negative regulation of calcium ion import	1.226882e-8
GO:0071584	negative regulation of zinc ion import	1.226882e-8
GO:0006364	rRNA processing	3.571556e-8
GO:0051955	regulation of amino acid transport	5.895484e-8
GO:0002036	regulation of L-glutamate transport	1.050165e-7
GO:0034766	negative regulation of ion transmembrane transport	1.661821e-7
GO:0032060	bleb assembly	2.120406e-7
GO:0016072	rRNA metabolic process	2.221501e-7
GO:0090075	relaxation of muscle	2.291216e-7
GO:0042254	ribosome biogenesis	3.897633e-7
GO:0002678	positive regulation of chronic inflammatory response	4.216360e-7
GO:0070574	cadmium ion transmembrane transport	5.074433e-7
GO:0070979	protein K11-linked ubiquitination	1.804715e-6
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.655361e-6
GO:0002676	regulation of chronic inflammatory response	2.779058e-6
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.944594e-6
GO:0015884	folic acid transport	3.811967e-6
GO:0006288	base-excision repair, DNA ligation	4.475891e-6
GO:0032790	ribosome disassembly	5.078915e-6
GO:0032532	regulation of microvillus length	5.087262e-6
GO:0048561	establishment of organ orientation	5.521828e-6
GO:0048752	semicircular canal morphogenesis	5.772351e-6
GO:0021819	layer formation in cerebral cortex	6.007234e-6
GO:0051299	centrosome separation	6.521758e-6
GO:0042538	hyperosmotic salinity response	7.996980e-6
GO:0071673	positive regulation of smooth muscle cell chemotaxis	9.613948e-6
GO:0031123	RNA 3'-end processing	1.260170e-5
GO:0055118	negative regulation of cardiac muscle contraction	1.294338e-5
GO:0043471	regulation of cellular carbohydrate catabolic process	1.353735e-5
GO:0045819	positive regulation of glycogen catabolic process	1.366651e-5
GO:0033169	histone H3-K9 demethylation	1.434456e-5
GO:0042696	menarche	1.444165e-5
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.918088e-5
GO:0032581	ER-dependent peroxisome organization	1.918482e-5
GO:0044070	regulation of anion transport	2.100198e-5
GO:0043487	regulation of RNA stability	2.322514e-5
GO:0071557	histone H3-K27 demethylation	2.392083e-5
GO:0035574	histone H4-K20 demethylation	2.392083e-5
GO:0051956	negative regulation of amino acid transport	2.406377e-5
GO:0022412	cellular process involved in reproduction in multicellular organism	2.663545e-5
GO:0001675	acrosome assembly	2.858984e-5
GO:0051645	Golgi localization	2.904789e-5
GO:0031124	mRNA 3'-end processing	2.953303e-5
GO:0046929	negative regulation of neurotransmitter secretion	3.196922e-5
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	3.212384e-5
GO:0042274	ribosomal small subunit biogenesis	3.376105e-5
GO:0010719	negative regulation of epithelial to mesenchymal transition	3.516666e-5
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3.825453e-5
GO:0006021	inositol biosynthetic process	4.266476e-5
GO:0042694	muscle cell fate specification	4.569491e-5
GO:0055119	relaxation of cardiac muscle	5.100908e-5
GO:0043488	regulation of mRNA stability	5.418727e-5
GO:0046655	folic acid metabolic process	5.662376e-5
GO:0045994	positive regulation of translational initiation by iron	5.894329e-5
GO:0002037	negative regulation of L-glutamate transport	5.894329e-5
GO:0018208	peptidyl-proline modification	6.156712e-5
GO:0060872	semicircular canal development	6.186358e-5
GO:0007100	mitotic centrosome separation	6.198045e-5
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	6.198045e-5
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.198045e-5
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.198045e-5
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	6.412555e-5
GO:0051452	intracellular pH reduction	6.818684e-5
GO:0040023	establishment of nucleus localization	7.320490e-5
GO:0000413	protein peptidyl-prolyl isomerization	7.471073e-5
GO:0040040	thermosensory behavior	8.362187e-5
GO:0015742	alpha-ketoglutarate transport	1.048052e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.115025e-4
GO:0034446	substrate adhesion-dependent cell spreading	1.129808e-4
GO:0048291	isotype switching to IgG isotypes	1.140851e-4
GO:0006844	acyl carnitine transport	1.140851e-4
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.140851e-4
GO:0002368	B cell cytokine production	1.140851e-4
GO:0034660	ncRNA metabolic process	1.151524e-4
GO:0035845	photoreceptor cell outer segment organization	1.278635e-4
GO:0030490	maturation of SSU-rRNA	1.383147e-4
GO:0010890	positive regulation of sequestering of triglyceride	1.514343e-4
GO:0045988	negative regulation of striated muscle contraction	1.514722e-4
GO:0035356	cellular triglyceride homeostasis	1.520595e-4
GO:0021759	globus pallidus development	1.558412e-4
GO:0060347	heart trabecula formation	1.562527e-4
GO:0014911	positive regulation of smooth muscle cell migration	1.619801e-4
GO:0048713	regulation of oligodendrocyte differentiation	1.733000e-4
GO:0006447	regulation of translational initiation by iron	1.844939e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	1.951750e-4
GO:0051181	cofactor transport	2.113750e-4
GO:0000416	positive regulation of histone H3-K36 methylation	2.167640e-4
GO:0048790	maintenance of presynaptic active zone structure	2.295497e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	2.295497e-4
GO:0046358	butyrate biosynthetic process	2.322824e-4
GO:0007614	short-term memory	2.324763e-4
GO:0019087	transformation of host cell by virus	2.612378e-4
GO:0042989	sequestering of actin monomers	2.698662e-4
GO:0090346	cellular organofluorine metabolic process	2.932252e-4
GO:0046210	nitric oxide catabolic process	2.932252e-4
GO:0043602	nitrate catabolic process	2.932252e-4
GO:0045851	pH reduction	3.162375e-4
GO:0097039	protein linear polyubiquitination	3.192364e-4
GO:0046939	nucleotide phosphorylation	3.222011e-4
GO:0010626	negative regulation of Schwann cell proliferation	3.246893e-4
GO:0071460	cellular response to cell-matrix adhesion	3.336748e-4
GO:0071671	regulation of smooth muscle cell chemotaxis	3.398203e-4
GO:0016340	calcium-dependent cell-matrix adhesion	3.425088e-4
GO:0043441	acetoacetic acid biosynthetic process	3.425088e-4
GO:0002002	regulation of angiotensin levels in blood	3.595106e-4
GO:0060033	anatomical structure regression	3.658009e-4
GO:0032717	negative regulation of interleukin-8 production	3.926028e-4
GO:0008033	tRNA processing	4.002524e-4
GO:0060913	cardiac cell fate determination	4.042741e-4
GO:0051298	centrosome duplication	4.242444e-4
GO:0034699	response to luteinizing hormone stimulus	4.286642e-4
GO:0060070	canonical Wnt receptor signaling pathway	4.353189e-4
GO:0051983	regulation of chromosome segregation	4.445959e-4
GO:0051790	short-chain fatty acid biosynthetic process	4.648814e-4
GO:0045175	basal protein localization	4.648814e-4
GO:0007109	cytokinesis, completion of separation	4.648814e-4
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	4.868215e-4
GO:0000154	rRNA modification	4.895968e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	4.916320e-4
GO:0030828	positive regulation of cGMP biosynthetic process	5.099518e-4
GO:0061384	heart trabecular morphogenesis	5.230425e-4
GO:0022601	menstrual cycle phase	5.581151e-4
GO:0045198	establishment of epithelial cell apical/basal polarity	5.907562e-4
GO:0060914	heart formation	5.952764e-4
GO:0008049	male courtship behavior	6.553313e-4
GO:0002016	regulation of blood volume by renin-angiotensin	6.873025e-4
GO:0034959	endothelin maturation	7.094969e-4
GO:0010814	substance P catabolic process	7.094969e-4
GO:0010816	calcitonin catabolic process	7.094969e-4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.126848e-4
GO:0015788	UDP-N-acetylglucosamine transport	7.164076e-4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.203380e-4
GO:0060430	lung saccule development	7.217804e-4
GO:0006482	protein demethylation	7.345951e-4
GO:0051103	DNA ligation involved in DNA repair	7.458444e-4
GO:0048384	retinoic acid receptor signaling pathway	7.493231e-4
GO:0045932	negative regulation of muscle contraction	7.542562e-4
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	7.621771e-4
GO:0003142	cardiogenic plate morphogenesis	7.621771e-4
GO:0030421	defecation	7.621771e-4
GO:0071816	tail-anchored membrane protein insertion into ER membrane	7.658920e-4
GO:0060042	retina morphogenesis in camera-type eye	7.850754e-4
GO:0048562	embryonic organ morphogenesis	7.993553e-4
GO:0030641	regulation of cellular pH	8.018398e-4
GO:0045948	positive regulation of translational initiation	8.213774e-4
GO:0033299	secretion of lysosomal enzymes	8.763978e-4
GO:0006659	phosphatidylserine biosynthetic process	8.955810e-4
GO:0060087	relaxation of vascular smooth muscle	9.076485e-4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	9.094429e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	9.335693e-4
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	9.612586e-4
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	9.923947e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	9.923947e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	9.923947e-4
GO:0045472	response to ether	9.981579e-4
GO:0035545	determination of left/right asymmetry in nervous system	9.981579e-4
GO:0046173	polyol biosynthetic process	1.003085e-3
GO:0044254	multicellular organismal protein catabolic process	1.150612e-3
GO:0014052	regulation of gamma-aminobutyric acid secretion	1.175224e-3
GO:0009648	photoperiodism	1.175224e-3
GO:0050847	progesterone receptor signaling pathway	1.231858e-3
GO:0060976	coronary vasculature development	1.231858e-3
GO:0003229	ventricular cardiac muscle tissue development	1.242131e-3
GO:0060009	Sertoli cell development	1.245060e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	1.273874e-3
GO:0070543	response to linoleic acid	1.319026e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.319026e-3
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	1.319026e-3
GO:0034696	response to prostaglandin F stimulus	1.319026e-3
GO:0009440	cyanate catabolic process	1.356793e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.364541e-3
GO:0007379	segment specification	1.364596e-3
GO:0051958	methotrexate transport	1.455369e-3
GO:0016557	peroxisome membrane biogenesis	1.455369e-3
GO:0001977	renal system process involved in regulation of blood volume	1.465493e-3
GO:0014044	Schwann cell development	1.550501e-3
GO:0045234	protein palmitoleylation	1.557408e-3
GO:0006948	induction by virus of host cell-cell fusion	1.557408e-3
GO:0060911	cardiac cell fate commitment	1.579966e-3
GO:0045637	regulation of myeloid cell differentiation	1.584749e-3
GO:0071934	thiamine transmembrane transport	1.659530e-3
GO:0016598	protein arginylation	1.659530e-3
GO:0032425	positive regulation of mismatch repair	1.688050e-3
GO:0001842	neural fold formation	1.688050e-3
GO:0051660	establishment of centrosome localization	1.745033e-3
GO:0021540	corpus callosum morphogenesis	1.745033e-3
GO:0014014	negative regulation of gliogenesis	1.745110e-3
GO:0010225	response to UV-C	1.830433e-3
GO:0035025	positive regulation of Rho protein signal transduction	1.834158e-3
GO:0007097	nuclear migration	1.834158e-3
GO:0060850	regulation of transcription involved in cell fate commitment	1.917550e-3
GO:0048664	neuron fate determination	1.921327e-3
GO:0060998	regulation of dendritic spine development	1.922870e-3
GO:0007163	establishment or maintenance of cell polarity	1.974894e-3
GO:0043585	nose morphogenesis	2.124952e-3
GO:0034389	lipid particle organization	2.153766e-3
GO:0042373	vitamin K metabolic process	2.153766e-3
GO:0032988	ribonucleoprotein complex disassembly	2.202938e-3
GO:0044268	multicellular organismal protein metabolic process	2.229033e-3
GO:0060177	regulation of angiotensin metabolic process	2.265077e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.285235e-3
GO:0051301	cell division	2.303165e-3
GO:0030538	embryonic genitalia morphogenesis	2.317259e-3
GO:0000088	mitotic prophase	2.344828e-3
GO:0006235	dTTP biosynthetic process	2.344828e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.374111e-3
GO:0018293	protein-FAD linkage	2.374111e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	2.374111e-3
GO:0035088	establishment or maintenance of apical/basal cell polarity	2.392590e-3
GO:0090307	spindle assembly involved in mitosis	2.409463e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	2.414183e-3
GO:0031064	negative regulation of histone deacetylation	2.450170e-3
GO:0032075	positive regulation of nuclease activity	2.586717e-3
GO:0060318	definitive erythrocyte differentiation	2.612597e-3
GO:0071529	cementum mineralization	2.612597e-3
GO:0032859	activation of Ral GTPase activity	2.612597e-3
GO:0034259	negative regulation of Rho GTPase activity	2.612597e-3
GO:2000119	negative regulation of sodium-dependent phosphate transport	2.616871e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.616871e-3
GO:0033126	positive regulation of GTP catabolic process	2.617551e-3
GO:0033505	floor plate morphogenesis	2.755531e-3
GO:0006999	nuclear pore organization	2.755531e-3
GO:0031167	rRNA methylation	2.755531e-3
GO:0048645	organ formation	2.792715e-3
GO:0007035	vacuolar acidification	2.857198e-3
GO:0070509	calcium ion import	2.857198e-3
GO:0061013	regulation of mRNA catabolic process	2.932463e-3
GO:0050779	RNA destabilization	2.987530e-3
GO:0007501	mesodermal cell fate specification	2.987530e-3
GO:0090241	negative regulation of histone H4 acetylation	3.097257e-3
GO:0014037	Schwann cell differentiation	3.099361e-3
GO:2000252	negative regulation of feeding behavior	3.124311e-3
GO:0072537	fibroblast activation	3.124311e-3
GO:0048557	embryonic digestive tract morphogenesis	3.137375e-3
GO:2000109	regulation of macrophage apoptosis	3.147483e-3
GO:0016577	histone demethylation	3.190768e-3
GO:0051453	regulation of intracellular pH	3.204801e-3
GO:0060005	vestibular reflex	3.230099e-3
GO:0043314	negative regulation of neutrophil degranulation	3.276507e-3
GO:0043461	proton-transporting ATP synthase complex assembly	3.327936e-3
GO:0061037	negative regulation of cartilage development	3.336801e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3.397498e-3
GO:0009584	detection of visible light	3.413226e-3
GO:0032926	negative regulation of activin receptor signaling pathway	3.470372e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	3.575616e-3
GO:0043456	regulation of pentose-phosphate shunt	3.595128e-3
GO:0042574	retinal metabolic process	3.683077e-3
GO:0048313	Golgi inheritance	3.684707e-3
GO:0002017	regulation of blood volume by renal aldosterone	3.684707e-3
GO:0031914	negative regulation of synaptic plasticity	3.684707e-3
GO:0060486	Clara cell differentiation	3.684725e-3
GO:0050717	positive regulation of interleukin-1 alpha secretion	3.763671e-3
GO:0006337	nucleosome disassembly	3.963442e-3
GO:0001773	myeloid dendritic cell activation	3.963442e-3
GO:0010701	positive regulation of norepinephrine secretion	4.054553e-3
GO:0040001	establishment of mitotic spindle localization	4.108587e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	4.216934e-3
GO:0022011	myelination in peripheral nervous system	4.217529e-3
GO:0001523	retinoid metabolic process	4.257082e-3
GO:0016101	diterpenoid metabolic process	4.316005e-3
GO:0034633	retinol transport	4.438893e-3
GO:0007141	male meiosis I	4.458179e-3
GO:0002367	cytokine production involved in immune response	4.479236e-3
GO:0006402	mRNA catabolic process	4.524619e-3
GO:0048663	neuron fate commitment	4.542203e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	4.557685e-3
GO:0043171	peptide catabolic process	4.606318e-3
GO:0060534	trachea cartilage development	4.808913e-3
GO:0060214	endocardium formation	4.808913e-3
GO:0032423	regulation of mismatch repair	4.813077e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	4.990414e-3
GO:0046293	formaldehyde biosynthetic process	5.129974e-3
GO:0019402	galactitol metabolic process	5.129974e-3
GO:0045908	negative regulation of vasodilation	5.129974e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	5.154843e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5.514750e-3
GO:0007522	visceral muscle development	5.531748e-3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	5.557273e-3
GO:0055098	response to low-density lipoprotein particle stimulus	5.558234e-3
GO:0014895	smooth muscle hypertrophy	5.573842e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	5.573842e-3
GO:0006843	mitochondrial citrate transport	5.573842e-3
GO:0051293	establishment of spindle localization	5.630029e-3
GO:0045818	negative regulation of glycogen catabolic process	5.732797e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	6.021322e-3
GO:0032312	regulation of ARF GTPase activity	6.078937e-3
GO:0000966	RNA 5'-end processing	6.085333e-3
GO:0060253	negative regulation of glial cell proliferation	6.311431e-3
GO:0043415	positive regulation of skeletal muscle tissue regeneration	6.312448e-3
GO:0060461	right lung morphogenesis	6.460414e-3
GO:0090131	mesenchyme migration	6.460414e-3
GO:0060446	branching involved in open tracheal system development	6.460414e-3
GO:0014822	detection of wounding	6.460414e-3
GO:0048371	lateral mesodermal cell differentiation	6.460414e-3
GO:0048613	embryonic ectodermal digestive tract morphogenesis	6.460414e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.469682e-3
GO:0006930	substrate-dependent cell migration, cell extension	6.528060e-3
GO:0043467	regulation of generation of precursor metabolites and energy	6.641948e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	6.680749e-3
GO:0090399	replicative senescence	6.690635e-3
GO:0051589	negative regulation of neurotransmitter transport	6.690635e-3
GO:0006265	DNA topological change	6.833201e-3
GO:0042572	retinol metabolic process	6.895285e-3
GO:0046015	regulation of transcription by glucose	6.913637e-3
GO:0000212	meiotic spindle organization	7.112998e-3
GO:0030220	platelet formation	7.130000e-3
GO:0006470	protein dephosphorylation	7.193388e-3
GO:0016311	dephosphorylation	7.356399e-3
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	7.406421e-3
GO:0045402	regulation of interleukin-4 biosynthetic process	7.477567e-3
GO:0042780	tRNA 3'-end processing	7.514857e-3
GO:0042418	epinephrine biosynthetic process	7.514857e-3
GO:0006585	dopamine biosynthetic process from tyrosine	7.514857e-3
GO:0032020	ISG15-protein conjugation	7.593823e-3
GO:0042662	negative regulation of mesodermal cell fate specification	7.637872e-3
GO:0051647	nucleus localization	7.785236e-3
GO:0045607	regulation of auditory receptor cell differentiation	7.830707e-3
GO:0033151	V(D)J recombination	7.969388e-3
GO:0060487	lung epithelial cell differentiation	7.986286e-3
GO:0048255	mRNA stabilization	8.000673e-3
GO:0014028	notochord formation	8.007345e-3
GO:0032661	regulation of interleukin-18 production	8.019930e-3
GO:0006885	regulation of pH	8.021090e-3
GO:0019478	D-amino acid catabolic process	8.058992e-3
GO:0001830	trophectodermal cell fate commitment	8.058992e-3
GO:0045684	positive regulation of epidermis development	8.173386e-3
GO:0001710	mesodermal cell fate commitment	8.173386e-3
GO:0000183	chromatin silencing at rDNA	8.330432e-3
GO:0003016	respiratory system process	8.372862e-3
GO:0060038	cardiac muscle cell proliferation	8.511287e-3
GO:0006369	termination of RNA polymerase II transcription	8.665907e-3
GO:0045039	protein import into mitochondrial inner membrane	8.708058e-3
GO:0046491	L-methylmalonyl-CoA metabolic process	8.939572e-3
GO:0002418	immune response to tumor cell	8.939572e-3
GO:0045875	negative regulation of sister chromatid cohesion	8.939572e-3
GO:0035886	vascular smooth muscle cell differentiation	9.018958e-3
GO:0014813	satellite cell commitment	9.119522e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	9.119522e-3
GO:0042214	terpene metabolic process	9.119522e-3
GO:0060282	positive regulation of oocyte development	9.131787e-3
GO:0032202	telomere assembly	9.146274e-3
GO:0072086	specification of loop of Henle identity	9.169118e-3
GO:0060999	positive regulation of dendritic spine development	9.185444e-3
GO:0007063	regulation of sister chromatid cohesion	9.185444e-3
GO:0030826	regulation of cGMP biosynthetic process	9.231691e-3
GO:0060216	definitive hemopoiesis	9.315991e-3
GO:0043313	regulation of neutrophil degranulation	9.476821e-3
GO:0060419	heart growth	9.477030e-3
GO:0018125	peptidyl-cysteine methylation	9.598072e-3
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	9.598072e-3
GO:0001921	positive regulation of receptor recycling	9.739907e-3
GO:0021801	cerebral cortex radial glia guided migration	9.875589e-3
GO:0007296	vitellogenesis	9.875589e-3
GO:0045773	positive regulation of axon extension	9.946945e-3
GO:0003417	growth plate cartilage development	9.961922e-3
GO:0042447	hormone catabolic process	9.997562e-3
GO:0046292	formaldehyde metabolic process	1.003139e-2
GO:0006401	RNA catabolic process	1.010245e-2
GO:0071168	protein localization to chromatin	1.025388e-2
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1.025388e-2
GO:0048368	lateral mesoderm development	1.025554e-2
GO:0070988	demethylation	1.068017e-2
GO:0016584	nucleosome positioning	1.074665e-2
GO:0045820	negative regulation of glycolysis	1.080597e-2
GO:0021895	cerebral cortex neuron differentiation	1.090654e-2
GO:0007216	metabotropic glutamate receptor signaling pathway	1.100217e-2
GO:0002357	defense response to tumor cell	1.101174e-2
GO:0060977	coronary vasculature morphogenesis	1.116901e-2
GO:0030917	midbrain-hindbrain boundary development	1.118169e-2
GO:0060008	Sertoli cell differentiation	1.132143e-2
GO:0040030	regulation of molecular function, epigenetic	1.155485e-2
GO:0003127	detection of nodal flow	1.155485e-2
GO:0090009	primitive streak formation	1.193911e-2
GO:0043091	L-arginine import	1.207701e-2
GO:0070839	divalent metal ion export	1.207701e-2
GO:0045342	MHC class II biosynthetic process	1.207701e-2
GO:0006876	cellular cadmium ion homeostasis	1.207701e-2
GO:0015707	nitrite transport	1.207701e-2
GO:0032632	interleukin-3 production	1.207701e-2
GO:0043132	NAD transport	1.208754e-2
GO:0043923	positive regulation by host of viral transcription	1.240110e-2
GO:0032730	positive regulation of interleukin-1 alpha production	1.242212e-2
GO:0001881	receptor recycling	1.242212e-2
GO:0070873	regulation of glycogen metabolic process	1.252638e-2
GO:0007098	centrosome cycle	1.254211e-2
GO:0045663	positive regulation of myoblast differentiation	1.254921e-2
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.255621e-2
GO:0048705	skeletal system morphogenesis	1.269998e-2
GO:0030309	poly-N-acetyllactosamine metabolic process	1.273319e-2
GO:0006942	regulation of striated muscle contraction	1.284651e-2
GO:0060712	spongiotrophoblast layer development	1.288163e-2
GO:0048568	embryonic organ development	1.302876e-2
GO:0007214	gamma-aminobutyric acid signaling pathway	1.317132e-2
GO:0006020	inositol metabolic process	1.331571e-2
GO:0060463	lung lobe morphogenesis	1.342937e-2
GO:0006310	DNA recombination	1.345438e-2
GO:0006430	lysyl-tRNA aminoacylation	1.347231e-2
GO:0006797	polyphosphate metabolic process	1.347231e-2
GO:0019805	quinolinate biosynthetic process	1.368051e-2
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.369265e-2
GO:0000132	establishment of mitotic spindle orientation	1.371034e-2
GO:0055012	ventricular cardiac muscle cell differentiation	1.374679e-2
GO:0055089	fatty acid homeostasis	1.380416e-2
GO:0002309	T cell proliferation involved in immune response	1.380416e-2
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.394611e-2
GO:0052314	phytoalexin metabolic process	1.395859e-2
GO:0060764	cell-cell signaling involved in mammary gland development	1.395859e-2
GO:0050908	detection of light stimulus involved in visual perception	1.395948e-2
GO:0006734	NADH metabolic process	1.402989e-2
GO:0071506	cellular response to mycophenolic acid	1.408990e-2
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.408990e-2
GO:0051953	negative regulation of amine transport	1.412841e-2
GO:0090239	regulation of histone H4 acetylation	1.433739e-2
GO:0048570	notochord morphogenesis	1.433739e-2
GO:0048617	embryonic foregut morphogenesis	1.453975e-2
GO:0002019	regulation of renal output by angiotensin	1.458760e-2
GO:0060711	labyrinthine layer development	1.460018e-2
GO:0045332	phospholipid translocation	1.483453e-2
GO:0048619	embryonic hindgut morphogenesis	1.500743e-2
GO:0006686	sphingomyelin biosynthetic process	1.514522e-2
GO:0006760	folic acid-containing compound metabolic process	1.515601e-2
GO:0051549	positive regulation of keratinocyte migration	1.520081e-2
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.520081e-2
GO:0006287	base-excision repair, gap-filling	1.521723e-2
GO:0051225	spindle assembly	1.533046e-2
GO:0045685	regulation of glial cell differentiation	1.542481e-2
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	1.548694e-2
GO:0043276	anoikis	1.548694e-2
GO:0060428	lung epithelium development	1.563263e-2
GO:0014013	regulation of gliogenesis	1.563441e-2
GO:0032530	regulation of microvillus organization	1.575605e-2
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.584473e-2
GO:0021532	neural tube patterning	1.652257e-2
GO:0051568	histone H3-K4 methylation	1.663089e-2
GO:0006929	substrate-dependent cell migration	1.665751e-2
GO:0006882	cellular zinc ion homeostasis	1.668026e-2
GO:0060795	cell fate commitment involved in formation of primary germ layers	1.677534e-2
GO:0048593	camera-type eye morphogenesis	1.694068e-2
GO:0032007	negative regulation of TOR signaling cascade	1.695238e-2
GO:0045608	negative regulation of auditory receptor cell differentiation	1.704935e-2
GO:0055017	cardiac muscle tissue growth	1.710795e-2
GO:0042693	muscle cell fate commitment	1.714692e-2
GO:0001522	pseudouridine synthesis	1.722750e-2
GO:0046931	pore complex assembly	1.729214e-2
GO:0043105	negative regulation of GTP cyclohydrolase I activity	1.729791e-2
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.729791e-2
GO:0035087	siRNA loading onto RISC involved in RNA interference	1.729791e-2
GO:2000111	positive regulation of macrophage apoptosis	1.734370e-2
GO:0051297	centrosome organization	1.742839e-2
GO:0019835	cytolysis	1.750073e-2
GO:0021670	lateral ventricle development	1.758137e-2
GO:0021591	ventricular system development	1.769499e-2
GO:0001845	phagolysosome assembly	1.780986e-2
GO:0051952	regulation of amine transport	1.784738e-2
GO:0072384	organelle transport along microtubule	1.827031e-2
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.827170e-2
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1.841806e-2
GO:0014051	gamma-aminobutyric acid secretion	1.845398e-2
GO:0072229	metanephric proximal convoluted tubule development	1.849769e-2
GO:0071799	cellular response to prostaglandin D stimulus	1.849769e-2
GO:0060816	random inactivation of X chromosome	1.849769e-2
GO:0007549	dosage compensation	1.852020e-2
GO:0060041	retina development in camera-type eye	1.870780e-2
GO:0071402	cellular response to lipoprotein particle stimulus	1.882875e-2
GO:0060458	right lung development	1.889226e-2
GO:0032836	glomerular basement membrane development	1.900057e-2
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.920161e-2
GO:0061162	establishment of monopolar cell polarity	1.923604e-2
GO:0009651	response to salt stress	1.943268e-2
GO:0030853	negative regulation of granulocyte differentiation	1.947929e-2
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.952704e-2
GO:0008292	acetylcholine biosynthetic process	1.952704e-2
GO:0060304	regulation of phosphatidylinositol dephosphorylation	2.026265e-2
GO:0051798	positive regulation of hair follicle development	2.056058e-2
GO:0071407	cellular response to organic cyclic compound	2.061545e-2
GO:0090231	regulation of spindle checkpoint	2.063667e-2
GO:0006266	DNA ligation	2.063667e-2
GO:0060479	lung cell differentiation	2.064976e-2
GO:0043543	protein acylation	2.066906e-2
GO:0048320	axial mesoderm formation	2.070747e-2
GO:0060947	cardiac vascular smooth muscle cell differentiation	2.075877e-2
GO:0055026	negative regulation of cardiac muscle tissue development	2.075877e-2
GO:0060242	contact inhibition	2.075877e-2
GO:0030225	macrophage differentiation	2.087919e-2
GO:0000959	mitochondrial RNA metabolic process	2.092171e-2
GO:0035928	rRNA import into mitochondrion	2.093476e-2
GO:2000249	regulation of actin cytoskeleton reorganization	2.098685e-2
GO:0006821	chloride transport	2.106037e-2
GO:0015872	dopamine transport	2.137520e-2
GO:0060438	trachea development	2.137567e-2
GO:0035089	establishment of apical/basal cell polarity	2.141125e-2
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	2.141125e-2
GO:0042136	neurotransmitter biosynthetic process	2.146671e-2
GO:0003206	cardiac chamber morphogenesis	2.166940e-2
GO:0042414	epinephrine metabolic process	2.175070e-2
GO:0071608	macrophage inflammatory protein-1 alpha production	2.175070e-2
GO:2000363	positive regulation of prostaglandin-E synthase activity	2.175070e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0033239	negative regulation of cellular amine metabolic process	5.087033e-12
GO:0016072	rRNA metabolic process	2.533845e-11
GO:0006364	rRNA processing	6.684822e-11
GO:0042254	ribosome biogenesis	1.213490e-10
GO:0045963	negative regulation of dopamine metabolic process	4.361248e-10
GO:0050668	positive regulation of homocysteine metabolic process	4.361248e-10
GO:0034660	ncRNA metabolic process	9.919417e-9
GO:0071843	cellular component biogenesis at cellular level	4.308772e-8
GO:0032418	lysosome localization	4.729760e-8
GO:0022613	ribonucleoprotein complex biogenesis	7.914233e-8
GO:0006396	RNA processing	1.160814e-7
GO:0031167	rRNA methylation	1.922333e-7
GO:0034470	ncRNA processing	1.960799e-7
GO:0051176	positive regulation of sulfur metabolic process	6.584683e-7
GO:0000154	rRNA modification	1.343611e-6
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.314629e-6
GO:0042424	catecholamine catabolic process	2.466051e-6
GO:0010498	proteasomal protein catabolic process	2.595797e-6
GO:0010467	gene expression	3.342525e-6
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	4.015976e-6
GO:0022417	protein maturation by protein folding	4.015976e-6
GO:0019047	provirus integration	7.263368e-6
GO:0090304	nucleic acid metabolic process	7.483733e-6
GO:0007049	cell cycle	8.810440e-6
GO:0044260	cellular macromolecule metabolic process	1.052194e-5
GO:0016070	RNA metabolic process	1.530563e-5
GO:0044265	cellular macromolecule catabolic process	2.016059e-5
GO:0070574	cadmium ion transmembrane transport	2.203699e-5
GO:0051303	establishment of chromosome localization	2.247464e-5
GO:0043558	regulation of translational initiation in response to stress	2.253408e-5
GO:0010900	negative regulation of phosphatidylcholine catabolic process	2.363713e-5
GO:0051603	proteolysis involved in cellular protein catabolic process	2.735538e-5
GO:0030163	protein catabolic process	2.975333e-5
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	3.176675e-5
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	3.176675e-5
GO:0034447	very-low-density lipoprotein particle clearance	3.507243e-5
GO:0006413	translational initiation	4.251695e-5
GO:0044257	cellular protein catabolic process	4.724973e-5
GO:0051310	metaphase plate congression	4.761740e-5
GO:0007214	gamma-aminobutyric acid signaling pathway	8.805305e-5
GO:0033091	positive regulation of immature T cell proliferation	1.032581e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	1.062846e-4
GO:0045116	protein neddylation	1.100092e-4
GO:0022403	cell cycle phase	1.117060e-4
GO:0043153	entrainment of circadian clock by photoperiod	1.127770e-4
GO:0070634	transepithelial ammonium transport	1.207387e-4
GO:0046502	uroporphyrinogen III metabolic process	1.230290e-4
GO:0032288	myelin assembly	1.265567e-4
GO:0021871	forebrain regionalization	1.329313e-4
GO:0006783	heme biosynthetic process	1.335999e-4
GO:0033238	regulation of cellular amine metabolic process	1.339567e-4
GO:0008380	RNA splicing	1.388618e-4
GO:0072061	inner medullary collecting duct development	1.397983e-4
GO:0072060	outer medullary collecting duct development	1.397983e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.397983e-4
GO:0010984	regulation of lipoprotein particle clearance	1.475231e-4
GO:0010891	negative regulation of sequestering of triglyceride	1.489873e-4
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.570085e-4
GO:0060535	trachea cartilage morphogenesis	1.673831e-4
GO:0010889	regulation of sequestering of triglyceride	1.719247e-4
GO:0032289	central nervous system myelin formation	1.735453e-4
GO:0009648	photoperiodism	1.735453e-4
GO:0015696	ammonium transport	1.796855e-4
GO:0072488	ammonium transmembrane transport	1.918529e-4
GO:0060482	lobar bronchus development	1.918529e-4
GO:0006427	histidyl-tRNA aminoacylation	1.957311e-4
GO:0044267	cellular protein metabolic process	1.993674e-4
GO:0042420	dopamine catabolic process	2.054663e-4
GO:0010468	regulation of gene expression	2.121845e-4
GO:0060534	trachea cartilage development	2.155808e-4
GO:0051568	histone H3-K4 methylation	2.315028e-4
GO:0000086	G2/M transition of mitotic cell cycle	2.363166e-4
GO:0006511	ubiquitin-dependent protein catabolic process	2.404877e-4
GO:0010870	positive regulation of receptor biosynthetic process	2.494008e-4
GO:0019941	modification-dependent protein catabolic process	2.628392e-4
GO:0007501	mesodermal cell fate specification	2.629490e-4
GO:0032922	circadian regulation of gene expression	2.629490e-4
GO:0034446	substrate adhesion-dependent cell spreading	2.802202e-4
GO:0043632	modification-dependent macromolecule catabolic process	3.079582e-4
GO:0000726	non-recombinational repair	3.079636e-4
GO:0045078	positive regulation of interferon-gamma biosynthetic process	3.160481e-4
GO:0051005	negative regulation of lipoprotein lipase activity	3.605890e-4
GO:0010556	regulation of macromolecule biosynthetic process	3.657039e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	3.773285e-4
GO:0009057	macromolecule catabolic process	3.980031e-4
GO:0007614	short-term memory	4.103781e-4
GO:0090042	tubulin deacetylation	4.777579e-4
GO:0070846	Hsp90 deacetylation	4.777579e-4
GO:0045072	regulation of interferon-gamma biosynthetic process	4.806186e-4
GO:2000971	negative regulation of detection of glucose	4.810999e-4
GO:2000976	regulation of transcription from RNA polymerase II promoter involved in detection of glucose	4.810999e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.810999e-4
GO:0000433	negative regulation of transcription from RNA polymerase II promoter by glucose	4.810999e-4
GO:0070165	positive regulation of adiponectin secretion	5.003742e-4
GO:0033031	positive regulation of neutrophil apoptosis	5.003742e-4
GO:0022402	cell cycle process	5.317930e-4
GO:0032929	negative regulation of superoxide anion generation	5.363089e-4
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	5.392177e-4
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	5.392177e-4
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	5.392177e-4
GO:0006268	DNA unwinding involved in replication	5.653047e-4
GO:0016071	mRNA metabolic process	5.674246e-4
GO:0048295	positive regulation of isotype switching to IgE isotypes	5.754647e-4
GO:0006713	glucocorticoid catabolic process	6.081873e-4
GO:0032060	bleb assembly	6.495203e-4
GO:0060696	regulation of phospholipid catabolic process	6.795003e-4
GO:0043060	meiotic metaphase I plate congression	7.077601e-4
GO:0072300	positive regulation of metanephric glomerulus development	7.553921e-4
GO:0060433	bronchus development	7.574025e-4
GO:0048665	neuron fate specification	7.593902e-4
GO:0006261	DNA-dependent DNA replication	7.998834e-4
GO:0060439	trachea morphogenesis	8.104127e-4
GO:0006367	transcription initiation from RNA polymerase II promoter	8.125130e-4
GO:0032928	regulation of superoxide anion generation	8.127967e-4
GO:0000279	M phase	8.284144e-4
GO:0010869	regulation of receptor biosynthetic process	8.972243e-4
GO:0010608	posttranscriptional regulation of gene expression	9.585253e-4
GO:0023019	signal transduction involved in regulation of gene expression	9.616447e-4
GO:0048478	replication fork protection	9.841941e-4
GO:0034501	protein localization to kinetochore	9.981952e-4
GO:0008611	ether lipid biosynthetic process	1.031841e-3
GO:0033083	regulation of immature T cell proliferation	1.086791e-3
GO:0048477	oogenesis	1.090282e-3
GO:0072054	renal outer medulla development	1.102048e-3
GO:0006306	DNA methylation	1.121854e-3
GO:0072053	renal inner medulla development	1.187579e-3
GO:0043555	regulation of translation in response to stress	1.187579e-3
GO:0032924	activin receptor signaling pathway	1.187579e-3
GO:0051301	cell division	1.264419e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.268450e-3
GO:0002016	regulation of blood volume by renin-angiotensin	1.268611e-3
GO:0072205	metanephric collecting duct development	1.273296e-3
GO:0042168	heme metabolic process	1.300390e-3
GO:0035566	regulation of metanephros size	1.365837e-3
GO:0006397	mRNA processing	1.373169e-3
GO:0014895	smooth muscle hypertrophy	1.378900e-3
GO:0046491	L-methylmalonyl-CoA metabolic process	1.378900e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	1.378900e-3
GO:0032446	protein modification by small protein conjugation	1.386205e-3
GO:0016568	chromatin modification	1.407632e-3
GO:0009649	entrainment of circadian clock	1.421530e-3
GO:0015780	nucleotide-sugar transport	1.470629e-3
GO:0070544	histone H3-K36 demethylation	1.593436e-3
GO:0009451	RNA modification	1.598937e-3
GO:0043412	macromolecule modification	1.619631e-3
GO:0008208	C21-steroid hormone catabolic process	1.649958e-3
GO:0006507	GPI anchor release	1.649958e-3
GO:0042178	xenobiotic catabolic process	1.683640e-3
GO:0006303	double-strand break repair via nonhomologous end joining	1.683640e-3
GO:0010985	negative regulation of lipoprotein particle clearance	1.737645e-3
GO:0002089	lens morphogenesis in camera-type eye	1.760980e-3
GO:0070179	D-serine biosynthetic process	1.802661e-3
GO:0009088	threonine biosynthetic process	1.802661e-3
GO:0010887	negative regulation of cholesterol storage	1.804365e-3
GO:0071243	cellular response to arsenic-containing substance	1.806703e-3
GO:0006352	transcription initiation, DNA-dependent	1.836322e-3
GO:0051594	detection of glucose	1.933866e-3
GO:0055015	ventricular cardiac muscle cell development	1.965662e-3
GO:0060425	lung morphogenesis	2.000182e-3
GO:0051386	regulation of nerve growth factor receptor signaling pathway	2.111603e-3
GO:0032259	methylation	2.115923e-3
GO:0034587	piRNA metabolic process	2.168903e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	2.170970e-3
GO:0001510	RNA methylation	2.333566e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2.343878e-3
GO:0030521	androgen receptor signaling pathway	2.373743e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	2.419588e-3
GO:0030421	defecation	2.513259e-3
GO:0006493	protein O-linked glycosylation	2.568870e-3
GO:0001705	ectoderm formation	2.591540e-3
GO:0019222	regulation of metabolic process	2.616565e-3
GO:0080090	regulation of primary metabolic process	2.642056e-3
GO:0031323	regulation of cellular metabolic process	2.668155e-3
GO:0050774	negative regulation of dendrite morphogenesis	2.668530e-3
GO:0031326	regulation of cellular biosynthetic process	2.678492e-3
GO:0035063	nuclear speck organization	2.700163e-3
GO:0018243	protein O-linked glycosylation via threonine	2.700163e-3
GO:0018242	protein O-linked glycosylation via serine	2.700163e-3
GO:0007080	mitotic metaphase plate congression	2.722477e-3
GO:0006325	chromatin organization	2.774723e-3
GO:0006904	vesicle docking involved in exocytosis	2.790767e-3
GO:0016567	protein ubiquitination	2.829948e-3
GO:0035967	cellular response to topologically incorrect protein	2.855198e-3
GO:0031507	heterochromatin formation	2.867250e-3
GO:0090212	negative regulation of establishment of blood-brain barrier	2.956459e-3
GO:0002638	negative regulation of immunoglobulin production	2.956459e-3
GO:0001811	negative regulation of type I hypersensitivity	2.956459e-3
GO:0071585	detoxification of cadmium ion	3.027427e-3
GO:0000255	allantoin metabolic process	3.084813e-3
GO:0006779	porphyrin-containing compound biosynthetic process	3.200713e-3
GO:0072298	regulation of metanephric glomerulus development	3.205871e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	3.206217e-3
GO:0010665	regulation of cardiac muscle cell apoptosis	3.230114e-3
GO:0009103	lipopolysaccharide biosynthetic process	3.265213e-3
GO:0060255	regulation of macromolecule metabolic process	3.285142e-3
GO:0090286	cytoskeletal anchoring at nuclear membrane	3.411680e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	3.411680e-3
GO:0033132	negative regulation of glucokinase activity	3.411680e-3
GO:0046882	negative regulation of follicle-stimulating hormone secretion	3.411680e-3
GO:0006417	regulation of translation	3.448846e-3
GO:0032508	DNA duplex unwinding	3.491691e-3
GO:0000819	sister chromatid segregation	3.583079e-3
GO:0070627	ferrous iron import	3.675936e-3
GO:0046416	D-amino acid metabolic process	3.675936e-3
GO:0015692	lead ion transport	3.675936e-3
GO:0015676	vanadium ion transport	3.675936e-3
GO:0006450	regulation of translational fidelity	3.696365e-3
GO:0090193	positive regulation of glomerulus development	3.837469e-3
GO:0061015	snRNA import into nucleus	3.940058e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	3.940058e-3
GO:0017187	peptidyl-glutamic acid carboxylation	3.940058e-3
GO:0051915	induction of synaptic plasticity by chemical substance	3.980635e-3
GO:0042135	neurotransmitter catabolic process	4.071347e-3
GO:0032099	negative regulation of appetite	4.240539e-3
GO:0090402	oncogene-induced senescence	4.290902e-3
GO:2000774	positive regulation of cellular senescence	4.290902e-3
GO:0035986	senescence-associated heterochromatin focus formation	4.290902e-3
GO:0072215	regulation of metanephros development	4.382459e-3
GO:0032392	DNA geometric change	4.524492e-3
GO:0070076	histone lysine demethylation	4.536046e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	4.577971e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	4.755456e-3
GO:0071480	cellular response to gamma radiation	4.877971e-3
GO:0032096	negative regulation of response to food	4.877971e-3
GO:0043984	histone H4-K16 acetylation	4.948590e-3
GO:0006668	sphinganine-1-phosphate metabolic process	4.948590e-3
GO:0034645	cellular macromolecule biosynthetic process	4.985069e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	5.086574e-3
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	5.127715e-3
GO:0034382	chylomicron remnant clearance	5.141873e-3
GO:0060536	cartilage morphogenesis	5.376534e-3
GO:0042231	interleukin-13 biosynthetic process	5.435160e-3
GO:2000256	positive regulation of male germ cell proliferation	5.435160e-3
GO:0019858	cytosine metabolic process	5.435160e-3
GO:0019428	allantoin biosynthetic process	5.435160e-3
GO:0007066	female meiosis sister chromatid cohesion	5.435160e-3
GO:0000070	mitotic sister chromatid segregation	5.571623e-3
GO:0022406	membrane docking	5.591286e-3
GO:0030575	nuclear body organization	5.640749e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	5.667398e-3
GO:0006463	steroid hormone receptor complex assembly	5.691413e-3
GO:0042053	regulation of dopamine metabolic process	5.730429e-3
GO:0035305	negative regulation of dephosphorylation	5.752388e-3
GO:0015879	carnitine transport	5.889474e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	5.907424e-3
GO:0006464	protein modification process	5.912814e-3
GO:0003254	regulation of membrane depolarization	6.129537e-3
GO:0051252	regulation of RNA metabolic process	6.235928e-3
GO:0016574	histone ubiquitination	6.247017e-3
GO:0008210	estrogen metabolic process	6.300781e-3
GO:0031503	protein complex localization	6.301517e-3
GO:0006366	transcription from RNA polymerase II promoter	6.318822e-3
GO:0046685	response to arsenic-containing substance	6.445565e-3
GO:0000729	DNA double-strand break processing	6.494527e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	6.494527e-3
GO:0000414	regulation of histone H3-K36 methylation	6.494527e-3
GO:0000089	mitotic metaphase	6.494527e-3
GO:0033240	positive regulation of cellular amine metabolic process	6.530956e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	6.631404e-3
GO:0051171	regulation of nitrogen compound metabolic process	6.697104e-3
GO:0006505	GPI anchor metabolic process	6.730409e-3
GO:0006264	mitochondrial DNA replication	6.757179e-3
GO:0000239	pachytene	6.757179e-3
GO:0051972	regulation of telomerase activity	6.784083e-3
GO:0045070	positive regulation of viral genome replication	6.804249e-3
GO:0051276	chromosome organization	6.908989e-3
GO:2000677	regulation of transcription regulatory region DNA binding	6.990840e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	7.012548e-3
GO:0042360	vitamin E metabolic process	7.082715e-3
GO:0060764	cell-cell signaling involved in mammary gland development	7.082715e-3
GO:2000678	negative regulation of transcription regulatory region DNA binding	7.345424e-3
GO:0048285	organelle fission	7.377950e-3
GO:0000278	mitotic cell cycle	7.698270e-3
GO:0008366	axon ensheathment	7.713969e-3
GO:0007059	chromosome segregation	7.758887e-3
GO:0060466	activation of meiosis involved in egg activation	7.972723e-3
GO:0048278	vesicle docking	8.037054e-3
GO:0018202	peptidyl-histidine modification	8.279663e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	8.361287e-3
GO:0070842	aggresome assembly	8.372446e-3
GO:0045918	negative regulation of cytolysis	8.372446e-3
GO:0051973	positive regulation of telomerase activity	8.372446e-3
GO:0007131	reciprocal meiotic recombination	8.398395e-3
GO:0006448	regulation of translational elongation	8.596108e-3
GO:0009889	regulation of biosynthetic process	8.608150e-3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	8.833517e-3
GO:0060586	multicellular organismal iron ion homeostasis	8.833517e-3
GO:0031915	positive regulation of synaptic plasticity	8.893077e-3
GO:0060037	pharyngeal system development	8.897701e-3
GO:0070163	regulation of adiponectin secretion	8.995932e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	8.995932e-3
GO:0060084	synaptic transmission involved in micturition	8.995932e-3
GO:0010986	positive regulation of lipoprotein particle clearance	8.995932e-3
GO:0006682	galactosylceramide biosynthetic process	8.995932e-3
GO:0016577	histone demethylation	9.086806e-3
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	9.099584e-3
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	9.099584e-3
GO:0031577	spindle checkpoint	9.233836e-3
GO:0016331	morphogenesis of embryonic epithelium	9.324238e-3
GO:0071557	histone H3-K27 demethylation	9.526742e-3
GO:0035574	histone H4-K20 demethylation	9.526742e-3
GO:0035518	histone H2A monoubiquitination	9.593738e-3
GO:0051318	G1 phase	9.879778e-3
GO:0070672	response to interleukin-15	9.945679e-3
GO:0071780	mitotic cell cycle G2/M transition checkpoint	1.003344e-2
GO:0001841	neural tube formation	1.005659e-2
GO:0009059	macromolecule biosynthetic process	1.009708e-2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.010091e-2
GO:0006433	prolyl-tRNA aminoacylation	1.010091e-2
GO:0072236	metanephric loop of Henle development	1.030656e-2
GO:0060033	anatomical structure regression	1.039953e-2
GO:0090319	positive regulation of chylomicron remodeling	1.044098e-2
GO:0090321	positive regulation of chylomicron remnant clearance	1.044098e-2
GO:0033315	meiotic cell cycle DNA replication checkpoint	1.044098e-2
GO:0010032	meiotic chromosome condensation	1.044098e-2
GO:0033084	regulation of immature T cell proliferation in thymus	1.048216e-2
GO:0034201	response to oleic acid	1.051281e-2
GO:0035444	nickel ion transmembrane transport	1.062058e-2
GO:0043170	macromolecule metabolic process	1.077607e-2
GO:0032277	negative regulation of gonadotropin secretion	1.086022e-2
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.086022e-2
GO:0016570	histone modification	1.148039e-2
GO:0000413	protein peptidyl-prolyl isomerization	1.151822e-2
GO:0042069	regulation of catecholamine metabolic process	1.166127e-2
GO:0045773	positive regulation of axon extension	1.172834e-2
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	1.183637e-2
GO:0048663	neuron fate commitment	1.186684e-2
GO:0000080	G1 phase of mitotic cell cycle	1.187722e-2
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.203453e-2
GO:0021549	cerebellum development	1.228801e-2
GO:0045132	meiotic chromosome segregation	1.249826e-2
GO:0055012	ventricular cardiac muscle cell differentiation	1.251194e-2
GO:0032107	regulation of response to nutrient levels	1.256995e-2
GO:0040029	regulation of gene expression, epigenetic	1.265890e-2
GO:0030968	endoplasmic reticulum unfolded protein response	1.267666e-2
GO:0006139	nucleobase-containing compound metabolic process	1.275939e-2
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.294692e-2
GO:0035434	copper ion transmembrane transport	1.313132e-2
GO:0018342	protein prenylation	1.321065e-2
GO:0001810	regulation of type I hypersensitivity	1.321065e-2
GO:0033683	nucleotide-excision repair, DNA incision	1.327649e-2
GO:0032571	response to vitamin K	1.327649e-2
GO:0042147	retrograde transport, endosome to Golgi	1.349895e-2
GO:0007067	mitosis	1.351408e-2
GO:0090218	positive regulation of lipid kinase activity	1.358718e-2
GO:0070368	positive regulation of hepatocyte differentiation	1.379145e-2
GO:0014805	smooth muscle adaptation	1.379145e-2
GO:0070671	response to interleukin-12	1.385749e-2
GO:0009082	branched chain family amino acid biosynthetic process	1.385749e-2
GO:0051188	cofactor biosynthetic process	1.387341e-2
GO:0070845	polyubiquitinated misfolded protein transport	1.389474e-2
GO:0009107	lipoate biosynthetic process	1.389474e-2
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	1.389474e-2
GO:0048705	skeletal system morphogenesis	1.464535e-2
GO:0060562	epithelial tube morphogenesis	1.472009e-2
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	1.479919e-2
GO:0006351	transcription, DNA-dependent	1.489572e-2
GO:0045143	homologous chromosome segregation	1.499022e-2
GO:0030513	positive regulation of BMP signaling pathway	1.504454e-2
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	1.511033e-2
GO:0009952	anterior/posterior pattern specification	1.522988e-2
GO:0018105	peptidyl-serine phosphorylation	1.530467e-2
GO:0061162	establishment of monopolar cell polarity	1.554449e-2
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.591190e-2
GO:0042696	menarche	1.591190e-2
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	1.591190e-2
GO:0017004	cytochrome complex assembly	1.591190e-2
GO:0009106	lipoate metabolic process	1.595484e-2
GO:0033211	adiponectin-mediated signaling pathway	1.604260e-2
GO:0000956	nuclear-transcribed mRNA catabolic process	1.625914e-2
GO:0006482	protein demethylation	1.635345e-2
GO:0021562	vestibulocochlear nerve development	1.637649e-2
GO:0090192	regulation of glomerulus development	1.646071e-2
GO:0051004	regulation of lipoprotein lipase activity	1.652882e-2
GO:0045666	positive regulation of neuron differentiation	1.655579e-2
GO:0016569	covalent chromatin modification	1.676154e-2
GO:0060096	serotonin secretion, neurotransmission	1.682027e-2
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	1.682027e-2
GO:0060691	epithelial cell maturation involved in salivary gland development	1.682027e-2
GO:0046604	positive regulation of mitotic centrosome separation	1.682027e-2
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	1.682027e-2
GO:0045609	positive regulation of auditory receptor cell differentiation	1.682027e-2
GO:2000682	positive regulation of rubidium ion transport	1.682027e-2
GO:0060975	cardioblast migration to the midline involved in heart field formation	1.682027e-2
GO:0060717	chorion development	1.682027e-2
GO:0042667	auditory receptor cell fate specification	1.682027e-2
GO:0003236	sinus venosus morphogenesis	1.682027e-2
GO:0003210	cardiac atrium formation	1.682027e-2
GO:0035826	rubidium ion transport	1.682027e-2
GO:0003259	cardioblast anterior-lateral migration	1.682027e-2
GO:0000416	positive regulation of histone H3-K36 methylation	1.682027e-2
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	1.682027e-2
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	1.682027e-2
GO:0010430	fatty acid omega-oxidation	1.682027e-2
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.684012e-2
GO:0031047	gene silencing by RNA	1.686510e-2
GO:2000036	regulation of stem cell maintenance	1.695256e-2
GO:0032774	RNA biosynthetic process	1.705299e-2
GO:0060347	heart trabecula formation	1.721018e-2
GO:0061001	regulation of dendritic spine morphogenesis	1.737674e-2
GO:0000002	mitochondrial genome maintenance	1.775508e-2
GO:0060579	ventral spinal cord interneuron fate commitment	1.779553e-2
GO:0045669	positive regulation of osteoblast differentiation	1.801271e-2
GO:0006563	L-serine metabolic process	1.833209e-2
GO:0043116	negative regulation of vascular permeability	1.841044e-2
GO:0007031	peroxisome organization	1.847587e-2
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	1.853965e-2
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	1.853965e-2
GO:0060179	male mating behavior	1.853965e-2
GO:0035519	protein K29-linked ubiquitination	1.853965e-2
GO:0051030	snRNA transport	1.853965e-2
GO:0051257	spindle midzone assembly involved in meiosis	1.853965e-2
GO:0000087	M phase of mitotic cell cycle	1.863843e-2
GO:0051325	interphase	1.886691e-2
GO:0042268	regulation of cytolysis	1.899020e-2
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.899020e-2
GO:0051546	keratinocyte migration	1.916661e-2
GO:0014012	peripheral nervous system axon regeneration	1.921378e-2
GO:0006101	citrate metabolic process	1.929727e-2
GO:0042273	ribosomal large subunit biogenesis	1.929727e-2
GO:0033169	histone H3-K9 demethylation	1.929727e-2
GO:0060438	trachea development	1.946067e-2
GO:0045663	positive regulation of myoblast differentiation	1.946067e-2
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	1.994231e-2
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	1.994231e-2
GO:0006235	dTTP biosynthetic process	1.994231e-2
GO:0003105	negative regulation of glomerular filtration	1.994231e-2
GO:0002019	regulation of renal output by angiotensin	1.995506e-2
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.008218e-2
GO:0000076	DNA replication checkpoint	2.008218e-2
GO:0001555	oocyte growth	2.008218e-2
GO:0006402	mRNA catabolic process	2.013664e-2
GO:0051329	interphase of mitotic cell cycle	2.032089e-2
GO:0060364	frontal suture morphogenesis	2.032308e-2
GO:0019374	galactolipid metabolic process	2.032308e-2
GO:0018209	peptidyl-serine modification	2.038655e-2
GO:0051149	positive regulation of muscle cell differentiation	2.039040e-2
GO:2000649	regulation of sodium ion transmembrane transporter activity	2.059853e-2
GO:0002663	positive regulation of B cell tolerance induction	2.059853e-2
GO:0032859	activation of Ral GTPase activity	2.059853e-2
GO:0006260	DNA replication	2.067762e-2
GO:0006355	regulation of transcription, DNA-dependent	2.083742e-2
GO:0045719	negative regulation of glycogen biosynthetic process	2.095493e-2
GO:0051351	positive regulation of ligase activity	2.129443e-2
GO:0032516	positive regulation of phosphoprotein phosphatase activity	2.145629e-2
GO:0006573	valine metabolic process	2.145629e-2
GO:0050685	positive regulation of mRNA processing	2.161748e-2
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.176794e-2
GO:0021521	ventral spinal cord interneuron specification	2.201259e-2
GO:0070633	transepithelial transport	2.230794e-2
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	2.242968e-2
GO:0006399	tRNA metabolic process	2.244234e-2
GO:0021759	globus pallidus development	2.247062e-2
GO:0021892	cerebral cortex GABAergic interneuron differentiation	2.265877e-2
GO:0046580	negative regulation of Ras protein signal transduction	2.278561e-2
GO:0015695	organic cation transport	2.312068e-2
GO:0032981	mitochondrial respiratory chain complex I assembly	2.327541e-2
GO:0060192	negative regulation of lipase activity	2.373625e-2
GO:0042552	myelination	2.376677e-2
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	2.390661e-2
GO:0071421	manganese ion transmembrane transport	2.390661e-2
GO:0001839	neural plate morphogenesis	2.395916e-2
GO:0070979	protein K11-linked ubiquitination	2.398427e-2
GO:0050691	regulation of defense response to virus by host	2.400192e-2
GO:0046836	glycolipid transport	2.410019e-2
GO:0061360	optic chiasma development	2.410019e-2
GO:2000597	positive regulation of optic nerve formation	2.410019e-2
GO:0090292	nuclear matrix anchoring at nuclear membrane	2.410019e-2
GO:0042095	interferon-gamma biosynthetic process	2.410019e-2
GO:0035799	ureter maturation	2.410019e-2
GO:0021633	optic nerve structural organization	2.410019e-2
GO:0016340	calcium-dependent cell-matrix adhesion	2.410019e-2
GO:0021650	vestibulocochlear nerve formation	2.410019e-2
GO:0046939	nucleotide phosphorylation	2.424118e-2
GO:0032479	regulation of type I interferon production	2.433200e-2
GO:0006730	one-carbon metabolic process	2.440999e-2
GO:0033131	regulation of glucokinase activity	2.446474e-2
GO:0007509	mesoderm migration involved in gastrulation	2.470922e-2
GO:0021798	forebrain dorsal/ventral pattern formation	2.479032e-2
GO:0021797	forebrain anterior/posterior pattern specification	2.479032e-2
GO:0045950	negative regulation of mitotic recombination	2.487783e-2
GO:0003406	retinal pigment epithelium development	2.487783e-2
GO:0040019	positive regulation of embryonic development	2.526698e-2
GO:0051457	maintenance of protein location in nucleus	2.556168e-2
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2.562589e-2
GO:0032364	oxygen homeostasis	2.578209e-2
GO:0042133	neurotransmitter metabolic process	2.584699e-2
GO:0003002	regionalization	2.602059e-2
GO:0030033	microvillus assembly	2.637675e-2
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	2.637675e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	2.637675e-2
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	2.682213e-2
GO:0071169	establishment of protein localization to chromatin	2.721813e-2
GO:0051790	short-chain fatty acid biosynthetic process	2.721813e-2
GO:2000781	positive regulation of double-strand break repair	2.721813e-2
GO:0032621	interleukin-18 production	2.721813e-2
GO:0007506	gonadal mesoderm development	2.721813e-2
GO:0032383	regulation of intracellular cholesterol transport	2.721813e-2
GO:0001546	preantral ovarian follicle growth	2.721813e-2
GO:0018344	protein geranylgeranylation	2.721813e-2