Novel motif:80

name:	motif80_CTCTGAGAGAA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002684	positive regulation of immune system process	1.245783e-19
GO:0002694	regulation of leukocyte activation	8.453855e-19
GO:0051249	regulation of lymphocyte activation	2.032633e-18
GO:0050865	regulation of cell activation	2.695439e-18
GO:0006954	inflammatory response	3.447635e-17
GO:0006952	defense response	4.332402e-16
GO:0032757	positive regulation of interleukin-8 production	1.372406e-15
GO:0050896	response to stimulus	1.900053e-15
GO:0002696	positive regulation of leukocyte activation	3.317499e-15
GO:0050789	regulation of biological process	6.077914e-15
GO:0050867	positive regulation of cell activation	6.962142e-15
GO:0050863	regulation of T cell activation	7.940664e-15
GO:0032103	positive regulation of response to external stimulus	1.227455e-14
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.236948e-14
GO:0051251	positive regulation of lymphocyte activation	6.381776e-14
GO:0051716	cellular response to stimulus	1.160174e-13
GO:0002376	immune system process	1.397223e-13
GO:0048584	positive regulation of response to stimulus	1.660470e-13
GO:0065007	biological regulation	4.388029e-13
GO:0050778	positive regulation of immune response	7.615781e-13
GO:0050794	regulation of cellular process	8.450537e-13
GO:0048583	regulation of response to stimulus	9.234657e-13
GO:0046709	IDP catabolic process	1.051943e-12
GO:0046032	ADP catabolic process	1.051943e-12
GO:0050727	regulation of inflammatory response	1.195710e-12
GO:0031349	positive regulation of defense response	1.663404e-12
GO:0031442	positive regulation of mRNA 3'-end processing	2.500376e-12
GO:0050870	positive regulation of T cell activation	3.435436e-12
GO:0050729	positive regulation of inflammatory response	4.750179e-12
GO:0002682	regulation of immune system process	8.335605e-12
GO:0031440	regulation of mRNA 3'-end processing	1.055598e-11
GO:0080134	regulation of response to stress	2.717471e-11
GO:0061014	positive regulation of mRNA catabolic process	2.781065e-11
GO:0032880	regulation of protein localization	5.126339e-11
GO:0006955	immune response	8.025659e-11
GO:0050776	regulation of immune response	8.849260e-11
GO:0007165	signal transduction	1.007319e-10
GO:0019216	regulation of lipid metabolic process	2.663451e-10
GO:0002526	acute inflammatory response	3.123034e-10
GO:0015889	cobalamin transport	3.674666e-10
GO:0009181	purine ribonucleoside diphosphate catabolic process	6.755795e-10
GO:0031347	regulation of defense response	7.277288e-10
GO:0030595	leukocyte chemotaxis	7.984017e-10
GO:0042493	response to drug	8.266300e-10
GO:0045321	leukocyte activation	9.540270e-10
GO:0032101	regulation of response to external stimulus	1.078410e-9
GO:0009595	detection of biotic stimulus	1.166180e-9
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	2.208883e-9
GO:0034114	regulation of heterotypic cell-cell adhesion	2.208883e-9
GO:0042993	positive regulation of transcription factor import into nucleus	3.491047e-9
GO:0023052	signaling	3.979466e-9
GO:0007166	cell surface receptor linked signaling pathway	4.943510e-9
GO:0007155	cell adhesion	5.045888e-9
GO:0048518	positive regulation of biological process	8.388423e-9
GO:0002253	activation of immune response	8.724397e-9
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	9.003800e-9
GO:0046649	lymphocyte activation	1.266377e-8
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.491470e-8
GO:0009611	response to wounding	1.642191e-8
GO:0045834	positive regulation of lipid metabolic process	1.722367e-8
GO:0009191	ribonucleoside diphosphate catabolic process	1.848636e-8
GO:0042110	T cell activation	1.902539e-8
GO:0060326	cell chemotaxis	2.113262e-8
GO:0007154	cell communication	2.168868e-8
GO:0032874	positive regulation of stress-activated MAPK cascade	2.755607e-8
GO:0061013	regulation of mRNA catabolic process	3.360987e-8
GO:0002439	chronic inflammatory response to antigenic stimulus	3.395138e-8
GO:0016576	histone dephosphorylation	4.678645e-8
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.841960e-8
GO:0034605	cellular response to heat	5.167277e-8
GO:0030324	lung development	5.282654e-8
GO:0030593	neutrophil chemotaxis	5.298323e-8
GO:0070163	regulation of adiponectin secretion	5.746278e-8
GO:0045216	cell-cell junction organization	6.118558e-8
GO:0031295	T cell costimulation	6.576850e-8
GO:0006953	acute-phase response	7.548784e-8
GO:0001660	fever generation	8.124619e-8
GO:0009607	response to biotic stimulus	8.248572e-8
GO:0014050	negative regulation of glutamate secretion	8.532794e-8
GO:0071637	regulation of monocyte chemotactic protein-1 production	8.871595e-8
GO:0032677	regulation of interleukin-8 production	9.638890e-8
GO:0034330	cell junction organization	1.013400e-7
GO:0070372	regulation of ERK1 and ERK2 cascade	1.044659e-7
GO:0048745	smooth muscle tissue development	1.055566e-7
GO:0072277	metanephric glomerular capillary formation	1.094489e-7
GO:0050685	positive regulation of mRNA processing	1.125523e-7
GO:0071726	cellular response to diacyl bacterial lipopeptide	1.329604e-7
GO:0042496	detection of diacyl bacterial lipopeptide	1.329604e-7
GO:0045086	positive regulation of interleukin-2 biosynthetic process	1.680079e-7
GO:0070164	negative regulation of adiponectin secretion	1.695607e-7
GO:0060355	positive regulation of cell adhesion molecule production	1.695607e-7
GO:0035505	positive regulation of myosin light chain kinase activity	1.695607e-7
GO:0072104	glomerular capillary formation	1.749502e-7
GO:0032728	positive regulation of interferon-beta production	1.789041e-7
GO:0030323	respiratory tube development	1.905035e-7
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.969754e-7
GO:0009605	response to external stimulus	2.013978e-7
GO:0045089	positive regulation of innate immune response	2.247930e-7
GO:0032735	positive regulation of interleukin-12 production	2.313961e-7
GO:0051707	response to other organism	2.559294e-7
GO:0002673	regulation of acute inflammatory response	2.577677e-7
GO:0034764	positive regulation of transmembrane transport	2.588723e-7
GO:0030155	regulation of cell adhesion	3.168088e-7
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	3.174049e-7
GO:0051930	regulation of sensory perception of pain	3.451674e-7
GO:0002764	immune response-regulating signaling pathway	3.457561e-7
GO:0045076	regulation of interleukin-2 biosynthetic process	3.902189e-7
GO:0010627	regulation of intracellular protein kinase cascade	4.006444e-7
GO:0010740	positive regulation of intracellular protein kinase cascade	4.211198e-7
GO:0010470	regulation of gastrulation	4.383151e-7
GO:0007181	transforming growth factor beta receptor complex assembly	4.835411e-7
GO:0009966	regulation of signal transduction	4.849393e-7
GO:0043410	positive regulation of MAPKKK cascade	4.940662e-7
GO:0034123	positive regulation of toll-like receptor signaling pathway	5.074996e-7
GO:0007565	female pregnancy	5.814648e-7
GO:0006950	response to stress	5.857500e-7
GO:0048522	positive regulation of cellular process	6.022394e-7
GO:0009386	translational attenuation	6.724137e-7
GO:0045940	positive regulation of steroid metabolic process	7.325774e-7
GO:0031341	regulation of cell killing	7.680922e-7
GO:0032648	regulation of interferon-beta production	8.005344e-7
GO:0002544	chronic inflammatory response	8.608491e-7
GO:0051050	positive regulation of transport	8.660024e-7
GO:0002709	regulation of T cell mediated immunity	8.799682e-7
GO:0072224	metanephric glomerulus development	9.133495e-7
GO:0016045	detection of bacterium	9.133495e-7
GO:0070663	regulation of leukocyte proliferation	9.489103e-7
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	9.587509e-7
GO:0046889	positive regulation of lipid biosynthetic process	9.777518e-7
GO:0045088	regulation of innate immune response	9.915295e-7
GO:0035690	cellular response to drug	1.028875e-6
GO:0002757	immune response-activating signal transduction	1.064568e-6
GO:0002706	regulation of lymphocyte mediated immunity	1.191078e-6
GO:2000193	positive regulation of fatty acid transport	1.224859e-6
GO:0044060	regulation of endocrine process	1.263103e-6
GO:0071670	smooth muscle cell chemotaxis	1.319873e-6
GO:0060981	cell migration involved in coronary angiogenesis	1.319873e-6
GO:0000255	allantoin metabolic process	1.326141e-6
GO:0008037	cell recognition	1.360094e-6
GO:0008283	cell proliferation	1.441776e-6
GO:0002440	production of molecular mediator of immune response	1.455489e-6
GO:0070542	response to fatty acid	1.487595e-6
GO:0070340	detection of bacterial lipopeptide	1.567032e-6
GO:0002699	positive regulation of immune effector process	1.650822e-6
GO:0070201	regulation of establishment of protein localization	1.691344e-6
GO:0010193	response to ozone	1.803096e-6
GO:0010535	positive regulation of activation of JAK2 kinase activity	1.839524e-6
GO:0032608	interferon-beta production	1.868327e-6
GO:0030730	sequestering of triglyceride	2.002843e-6
GO:0032872	regulation of stress-activated MAPK cascade	2.214992e-6
GO:0008284	positive regulation of cell proliferation	2.227898e-6
GO:0002708	positive regulation of lymphocyte mediated immunity	2.439217e-6
GO:0071727	cellular response to triacyl bacterial lipopeptide	2.443118e-6
GO:0042495	detection of triacyl bacterial lipopeptide	2.443118e-6
GO:0021858	GABAergic neuron differentiation in basal ganglia	2.708724e-6
GO:0009988	cell-cell recognition	2.854952e-6
GO:0042063	gliogenesis	2.972535e-6
GO:0032663	regulation of interleukin-2 production	3.003270e-6
GO:0032944	regulation of mononuclear cell proliferation	3.098092e-6
GO:0070374	positive regulation of ERK1 and ERK2 cascade	3.376421e-6
GO:0042744	hydrogen peroxide catabolic process	3.386562e-6
GO:0001967	suckling behavior	3.453508e-6
GO:0032308	positive regulation of prostaglandin secretion	3.484839e-6
GO:0051272	positive regulation of cellular component movement	3.733473e-6
GO:0008306	associative learning	3.885931e-6
GO:0042990	regulation of transcription factor import into nucleus	4.170803e-6
GO:0070665	positive regulation of leukocyte proliferation	4.206985e-6
GO:0002703	regulation of leukocyte mediated immunity	4.403427e-6
GO:0050900	leukocyte migration	4.431347e-6
GO:0015893	drug transport	4.519562e-6
GO:0032879	regulation of localization	4.564620e-6
GO:0002675	positive regulation of acute inflammatory response	4.733852e-6
GO:0032675	regulation of interleukin-6 production	4.757179e-6
GO:0042178	xenobiotic catabolic process	4.975447e-6
GO:0002820	negative regulation of adaptive immune response	5.321941e-6
GO:0035295	tube development	5.523911e-6
GO:0032892	positive regulation of organic acid transport	5.725586e-6
GO:0043408	regulation of MAPKKK cascade	5.758414e-6
GO:0023051	regulation of signaling	6.058121e-6
GO:0042129	regulation of T cell proliferation	6.155668e-6
GO:0032946	positive regulation of mononuclear cell proliferation	6.517348e-6
GO:0050670	regulation of lymphocyte proliferation	6.929451e-6
GO:0040017	positive regulation of locomotion	6.958245e-6
GO:0009617	response to bacterium	7.033463e-6
GO:0042221	response to chemical stimulus	7.066738e-6
GO:0016998	cell wall macromolecule catabolic process	7.099537e-6
GO:0032760	positive regulation of tumor necrosis factor production	7.353923e-6
GO:0033523	histone H2B ubiquitination	7.498631e-6
GO:0045087	innate immune response	7.703144e-6
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	7.782506e-6
GO:0020028	hemoglobin import	7.855297e-6
GO:0002449	lymphocyte mediated immunity	7.912937e-6
GO:0032481	positive regulation of type I interferon production	8.784138e-6
GO:0016477	cell migration	8.996745e-6
GO:0010646	regulation of cell communication	9.149451e-6
GO:0051240	positive regulation of multicellular organismal process	9.177344e-6
GO:0032370	positive regulation of lipid transport	9.339357e-6
GO:0090030	regulation of steroid hormone biosynthetic process	9.790917e-6
GO:0001771	immunological synapse formation	1.009447e-5
GO:0010647	positive regulation of cell communication	1.050109e-5
GO:0014826	vein smooth muscle contraction	1.055811e-5
GO:0030091	protein repair	1.092261e-5
GO:0032733	positive regulation of interleukin-10 production	1.099745e-5
GO:0044036	cell wall macromolecule metabolic process	1.174219e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.193478e-5
GO:0046890	regulation of lipid biosynthetic process	1.205293e-5
GO:0002437	inflammatory response to antigenic stimulus	1.225716e-5
GO:0023056	positive regulation of signaling	1.244378e-5
GO:0045410	positive regulation of interleukin-6 biosynthetic process	1.317095e-5
GO:2000465	regulation of glycogen (starch) synthase activity	1.326901e-5
GO:0009410	response to xenobiotic stimulus	1.326928e-5
GO:2000147	positive regulation of cell motility	1.396541e-5
GO:0032490	detection of molecule of bacterial origin	1.397118e-5
GO:0002697	regulation of immune effector process	1.402324e-5
GO:0051222	positive regulation of protein transport	1.419422e-5
GO:0006629	lipid metabolic process	1.472258e-5
GO:0050671	positive regulation of lymphocyte proliferation	1.583778e-5
GO:0050996	positive regulation of lipid catabolic process	1.589023e-5
GO:0006805	xenobiotic metabolic process	1.628540e-5
GO:0045058	T cell selection	1.645011e-5
GO:0051223	regulation of protein transport	1.651373e-5
GO:0014821	phasic smooth muscle contraction	1.689030e-5
GO:0034329	cell junction assembly	1.701203e-5
GO:0018108	peptidyl-tyrosine phosphorylation	1.744470e-5
GO:0010893	positive regulation of steroid biosynthetic process	1.760049e-5
GO:0032355	response to estradiol stimulus	1.830575e-5
GO:0042269	regulation of natural killer cell mediated cytotoxicity	1.831971e-5
GO:0030335	positive regulation of cell migration	1.905466e-5
GO:0071466	cellular response to xenobiotic stimulus	1.914193e-5
GO:0043687	post-translational protein modification	1.940660e-5
GO:0051345	positive regulation of hydrolase activity	1.987975e-5
GO:0001775	cell activation	2.074593e-5
GO:0009967	positive regulation of signal transduction	2.137001e-5
GO:0034201	response to oleic acid	2.166847e-5
GO:2000191	regulation of fatty acid transport	2.177495e-5
GO:0031343	positive regulation of cell killing	2.189452e-5
GO:0030098	lymphocyte differentiation	2.196982e-5
GO:0032741	positive regulation of interleukin-18 production	2.320965e-5
GO:0060479	lung cell differentiation	2.336600e-5
GO:0042307	positive regulation of protein import into nucleus	2.458319e-5
GO:0070301	cellular response to hydrogen peroxide	2.465186e-5
GO:0051336	regulation of hydrolase activity	2.479712e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.535124e-5
GO:0016046	detection of fungus	2.535124e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.535124e-5
GO:0051302	regulation of cell division	2.554400e-5
GO:0035645	enteric smooth muscle cell differentiation	2.583064e-5
GO:0051602	response to electrical stimulus	2.588509e-5
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	2.603643e-5
GO:0030855	epithelial cell differentiation	2.656582e-5
GO:0060745	mammary gland branching involved in pregnancy	2.797270e-5
GO:0034115	negative regulation of heterotypic cell-cell adhesion	2.902628e-5
GO:0071221	cellular response to bacterial lipopeptide	2.976986e-5
GO:0034121	regulation of toll-like receptor signaling pathway	2.978677e-5
GO:0034767	positive regulation of ion transmembrane transport	3.008383e-5
GO:0033566	gamma-tubulin complex localization	3.011686e-5
GO:0007566	embryo implantation	3.051301e-5
GO:0051270	regulation of cellular component movement	3.077136e-5
GO:0043462	regulation of ATPase activity	3.259345e-5
GO:0048013	ephrin receptor signaling pathway	3.275601e-5
GO:0032386	regulation of intracellular transport	3.288497e-5
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	3.312873e-5
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	3.312873e-5
GO:0032738	positive regulation of interleukin-15 production	3.312873e-5
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	3.375708e-5
GO:0033127	regulation of histone phosphorylation	3.502513e-5
GO:0009791	post-embryonic development	3.539491e-5
GO:2000178	negative regulation of neural precursor cell proliferation	3.561441e-5
GO:0018212	peptidyl-tyrosine modification	3.643176e-5
GO:0001659	temperature homeostasis	3.730552e-5
GO:0032543	mitochondrial translation	3.762120e-5
GO:0050921	positive regulation of chemotaxis	3.774183e-5
GO:0008272	sulfate transport	3.837240e-5
GO:0043603	cellular amide metabolic process	3.930859e-5
GO:0033993	response to lipid	4.335334e-5
GO:0045879	negative regulation of smoothened signaling pathway	4.390583e-5
GO:0002819	regulation of adaptive immune response	4.403535e-5
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	4.509653e-5
GO:0072239	metanephric glomerulus vasculature development	4.548136e-5
GO:0043085	positive regulation of catalytic activity	4.627033e-5
GO:0032501	multicellular organismal process	4.656116e-5
GO:0009987	cellular process	4.733908e-5
GO:0019477	L-lysine catabolic process	4.812908e-5
GO:0006911	phagocytosis, engulfment	4.931008e-5
GO:2001022	positive regulation of response to DNA damage stimulus	4.981383e-5
GO:0006349	regulation of gene expression by genetic imprinting	5.055571e-5
GO:0032722	positive regulation of chemokine production	5.218824e-5
GO:0051135	positive regulation of NK T cell activation	5.230138e-5
GO:0014070	response to organic cyclic compound	5.232133e-5
GO:0009649	entrainment of circadian clock	5.369752e-5
GO:0030728	ovulation	5.443709e-5
GO:0050715	positive regulation of cytokine secretion	5.683988e-5
GO:0019218	regulation of steroid metabolic process	5.792113e-5
GO:0048520	positive regulation of behavior	5.886408e-5
GO:0060487	lung epithelial cell differentiation	5.926983e-5
GO:0033129	positive regulation of histone phosphorylation	6.335094e-5
GO:0042345	regulation of NF-kappaB import into nucleus	6.497231e-5
GO:0033077	T cell differentiation in thymus	6.539852e-5
GO:0030217	T cell differentiation	6.559183e-5
GO:0032715	negative regulation of interleukin-6 production	6.615727e-5
GO:0032496	response to lipopolysaccharide	6.814893e-5
GO:0051049	regulation of transport	6.848373e-5
GO:0060429	epithelium development	6.894215e-5
GO:0007252	I-kappaB phosphorylation	6.952726e-5
GO:0060541	respiratory system development	7.235007e-5
GO:0006083	acetate metabolic process	7.417603e-5
GO:0070309	lens fiber cell morphogenesis	7.603828e-5
GO:0032661	regulation of interleukin-18 production	7.603828e-5
GO:0014829	vascular smooth muscle contraction	7.632761e-5
GO:0061138	morphogenesis of a branching epithelium	7.703934e-5
GO:0043255	regulation of carbohydrate biosynthetic process	8.425592e-5
GO:0002377	immunoglobulin production	8.506792e-5
GO:0002521	leukocyte differentiation	8.517978e-5
GO:0051238	sequestering of metal ion	8.791129e-5
GO:0042127	regulation of cell proliferation	8.818441e-5
GO:0030201	heparan sulfate proteoglycan metabolic process	8.877020e-5
GO:0001819	positive regulation of cytokine production	9.018750e-5
GO:0032388	positive regulation of intracellular transport	9.297054e-5
GO:0071223	cellular response to lipoteichoic acid	9.499625e-5
GO:0048246	macrophage chemotaxis	9.623587e-5
GO:0048585	negative regulation of response to stimulus	9.641923e-5
GO:0050714	positive regulation of protein secretion	9.709539e-5
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	9.815333e-5
GO:0002088	lens development in camera-type eye	9.835009e-5
GO:0050777	negative regulation of immune response	9.925107e-5
GO:0042743	hydrogen peroxide metabolic process	1.008475e-4
GO:0032755	positive regulation of interleukin-6 production	1.058621e-4
GO:2000736	regulation of stem cell differentiation	1.059202e-4
GO:0090398	cellular senescence	1.087284e-4
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	1.096533e-4
GO:2000756	regulation of peptidyl-lysine acetylation	1.102481e-4
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.110903e-4
GO:0002711	positive regulation of T cell mediated immunity	1.123756e-4
GO:0046323	glucose import	1.163690e-4
GO:0007497	posterior midgut development	1.163690e-4
GO:2000278	regulation of DNA biosynthetic process	1.202265e-4
GO:0045619	regulation of lymphocyte differentiation	1.202909e-4
GO:0034332	adherens junction organization	1.208403e-4
GO:0046688	response to copper ion	1.216189e-4
GO:0009888	tissue development	1.241174e-4
GO:0008211	glucocorticoid metabolic process	1.269976e-4
GO:0045580	regulation of T cell differentiation	1.296187e-4
GO:0070593	dendrite self-avoidance	1.312369e-4
GO:0048870	cell motility	1.328705e-4
GO:0002639	positive regulation of immunoglobulin production	1.342477e-4
GO:0032655	regulation of interleukin-12 production	1.342689e-4
GO:0043627	response to estrogen stimulus	1.347295e-4
GO:0090316	positive regulation of intracellular protein transport	1.373346e-4
GO:0002237	response to molecule of bacterial origin	1.374390e-4
GO:0009628	response to abiotic stimulus	1.388122e-4
GO:0032680	regulation of tumor necrosis factor production	1.393742e-4
GO:0001543	ovarian follicle rupture	1.441797e-4
GO:0055080	cation homeostasis	1.488564e-4
GO:0014048	regulation of glutamate secretion	1.497207e-4
GO:0034629	cellular protein complex localization	1.529786e-4
GO:0032729	positive regulation of interferon-gamma production	1.539975e-4
GO:0032700	negative regulation of interleukin-17 production	1.540418e-4
GO:0016064	immunoglobulin mediated immune response	1.542014e-4
GO:0044093	positive regulation of molecular function	1.577782e-4
GO:0071157	negative regulation of cell cycle arrest	1.578703e-4
GO:0046330	positive regulation of JNK cascade	1.579251e-4
GO:0045726	positive regulation of integrin biosynthetic process	1.625335e-4
GO:0046824	positive regulation of nucleocytoplasmic transport	1.639821e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.649819e-4
GO:0048790	maintenance of presynaptic active zone structure	1.649819e-4
GO:0002355	detection of tumor cell	1.649819e-4
GO:0019227	neuronal action potential propagation	1.651132e-4
GO:0048541	Peyer's patch development	1.652169e-4
GO:0042742	defense response to bacterium	1.655518e-4
GO:0042443	phenylethylamine metabolic process	1.703524e-4
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	1.715614e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.737836e-4
GO:0033033	negative regulation of myeloid cell apoptosis	1.822760e-4
GO:0033211	adiponectin-mediated signaling pathway	1.825736e-4
GO:0032387	negative regulation of intracellular transport	1.840955e-4
GO:0051704	multi-organism process	1.881318e-4
GO:0007174	epidermal growth factor catabolic process	1.887188e-4
GO:0008219	cell death	1.898273e-4
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	1.907689e-4
GO:0002218	activation of innate immune response	1.970794e-4
GO:0051781	positive regulation of cell division	1.985082e-4
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.990836e-4
GO:0035065	regulation of histone acetylation	1.998621e-4
GO:0042306	regulation of protein import into nucleus	2.025222e-4
GO:0050728	negative regulation of inflammatory response	2.084771e-4
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	2.122291e-4
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	2.122291e-4
GO:0050920	regulation of chemotaxis	2.141200e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	2.141565e-4
GO:0046449	creatinine metabolic process	2.142206e-4
GO:0048754	branching morphogenesis of a tube	2.200421e-4
GO:0033157	regulation of intracellular protein transport	2.208328e-4
GO:0009266	response to temperature stimulus	2.337324e-4
GO:0032368	regulation of lipid transport	2.355708e-4
GO:0019724	B cell mediated immunity	2.359161e-4
GO:0001914	regulation of T cell mediated cytotoxicity	2.453843e-4
GO:0048015	phosphatidylinositol-mediated signaling	2.458486e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	2.531542e-4
GO:0010536	positive regulation of activation of Janus kinase activity	2.537268e-4
GO:0042102	positive regulation of T cell proliferation	2.665461e-4
GO:0060341	regulation of cellular localization	2.682435e-4
GO:0002329	pre-B cell differentiation	2.791308e-4
GO:0035247	peptidyl-arginine omega-N-methylation	2.796762e-4
GO:0040012	regulation of locomotion	2.832949e-4
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.860738e-4
GO:0007162	negative regulation of cell adhesion	2.882590e-4
GO:0030334	regulation of cell migration	2.890124e-4
GO:0034103	regulation of tissue remodeling	2.896966e-4
GO:0006069	ethanol oxidation	2.937015e-4
GO:0033026	negative regulation of mast cell apoptosis	2.938442e-4
GO:0016265	death	3.019212e-4
GO:0009620	response to fungus	3.041624e-4
GO:0002252	immune effector process	3.089297e-4
GO:0050829	defense response to Gram-negative bacterium	3.114942e-4
GO:0061290	canonical Wnt receptor signaling pathway involved in metanephric kidney development	3.141784e-4
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	3.166471e-4
GO:0007009	plasma membrane organization	3.183829e-4
GO:0006880	intracellular sequestering of iron ion	3.196108e-4
GO:0050790	regulation of catalytic activity	3.231002e-4
GO:0009101	glycoprotein biosynthetic process	3.280716e-4
GO:0002426	immunoglobulin production in mucosal tissue	3.281626e-4
GO:0010001	glial cell differentiation	3.299862e-4
GO:0010693	negative regulation of alkaline phosphatase activity	3.371152e-4
GO:0002282	microglial cell activation involved in immune response	3.469957e-4
GO:0051145	smooth muscle cell differentiation	3.480588e-4
GO:0080135	regulation of cellular response to stress	3.516066e-4
GO:2000036	regulation of stem cell maintenance	3.569003e-4
GO:0002839	positive regulation of immune response to tumor cell	3.597425e-4
GO:0006487	protein N-linked glycosylation	3.653224e-4
GO:0009408	response to heat	3.709692e-4
GO:2000145	regulation of cell motility	3.719127e-4
GO:0050707	regulation of cytokine secretion	3.850872e-4
GO:0007549	dosage compensation	3.892390e-4
GO:0060416	response to growth hormone stimulus	3.903569e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	3.913090e-4
GO:0030259	lipid glycosylation	3.947220e-4
GO:0015914	phospholipid transport	3.974517e-4
GO:0070207	protein homotrimerization	3.981713e-4
GO:2000171	negative regulation of dendrite development	3.985958e-4
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	4.051419e-4
GO:2000836	positive regulation of androgen secretion	4.051419e-4
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	4.051419e-4
GO:0060236	regulation of mitotic spindle organization	4.051419e-4
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	4.051419e-4
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	4.051922e-4
GO:0048286	lung alveolus development	4.078302e-4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	4.084183e-4
GO:0002669	positive regulation of T cell anergy	4.086266e-4
GO:0014909	smooth muscle cell migration	4.121639e-4
GO:0022603	regulation of anatomical structure morphogenesis	4.168904e-4
GO:0033591	response to L-ascorbic acid	4.264547e-4
GO:0050708	regulation of protein secretion	4.348062e-4
GO:0048537	mucosal-associated lymphoid tissue development	4.393209e-4
GO:0002230	positive regulation of defense response to virus by host	4.405547e-4
GO:0035066	positive regulation of histone acetylation	4.428570e-4
GO:0051128	regulation of cellular component organization	4.451375e-4
GO:0008347	glial cell migration	4.476986e-4
GO:0071624	positive regulation of granulocyte chemotaxis	4.542306e-4
GO:0019428	allantoin biosynthetic process	4.542306e-4
GO:0032328	alanine transport	4.557948e-4
GO:0050926	regulation of positive chemotaxis	4.578453e-4
GO:0051047	positive regulation of secretion	4.596355e-4
GO:0030258	lipid modification	4.638816e-4
GO:0045785	positive regulation of cell adhesion	4.646858e-4
GO:0033032	regulation of myeloid cell apoptosis	4.679111e-4
GO:0012501	programmed cell death	4.863495e-4
GO:0014012	peripheral nervous system axon regeneration	4.865897e-4
GO:0060135	maternal process involved in female pregnancy	4.929479e-4
GO:0007156	homophilic cell adhesion	4.966737e-4
GO:0002710	negative regulation of T cell mediated immunity	4.992844e-4
GO:0010243	response to organic nitrogen	5.036015e-4
GO:0006855	drug transmembrane transport	5.250511e-4
GO:0034454	microtubule anchoring at centrosome	5.296666e-4
GO:0040011	locomotion	5.350376e-4
GO:0045582	positive regulation of T cell differentiation	5.385524e-4
GO:0071514	genetic imprinting	5.406631e-4
GO:0070257	positive regulation of mucus secretion	5.446127e-4
GO:0005989	lactose biosynthetic process	5.446127e-4
GO:0071780	mitotic cell cycle G2/M transition checkpoint	5.448633e-4
GO:0018279	protein N-linked glycosylation via asparagine	5.499684e-4
GO:0072102	glomerulus morphogenesis	5.502565e-4
GO:0043550	regulation of lipid kinase activity	5.632543e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	5.722257e-4
GO:0031329	regulation of cellular catabolic process	5.774018e-4
GO:0072210	metanephric nephron development	5.890014e-4
GO:0051494	negative regulation of cytoskeleton organization	6.032527e-4
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	6.067778e-4
GO:0048523	negative regulation of cellular process	6.106297e-4
GO:0032781	positive regulation of ATPase activity	6.147079e-4
GO:0032367	intracellular cholesterol transport	6.148332e-4
GO:0032647	regulation of interferon-alpha production	6.209338e-4
GO:0014805	smooth muscle adaptation	6.209338e-4
GO:0045113	regulation of integrin biosynthetic process	6.210851e-4
GO:0046544	development of secondary male sexual characteristics	6.469006e-4
GO:0007601	visual perception	6.484879e-4
GO:0051016	barbed-end actin filament capping	6.548835e-4
GO:0070085	glycosylation	6.592713e-4
GO:0043242	negative regulation of protein complex disassembly	6.814868e-4
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	6.832262e-4
GO:0065008	regulation of biological quality	6.868920e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0009605	response to external stimulus	8.248572e-15
GO:0050896	response to stimulus	1.810927e-13
GO:0002252	immune effector process	6.736472e-13
GO:0051704	multi-organism process	1.163459e-12
GO:0006955	immune response	8.960929e-12
GO:0002443	leukocyte mediated immunity	1.051069e-11
GO:0042221	response to chemical stimulus	1.176168e-11
GO:0009617	response to bacterium	2.134715e-11
GO:0051707	response to other organism	3.243943e-11
GO:0016064	immunoglobulin mediated immune response	4.147130e-11
GO:0019724	B cell mediated immunity	4.438112e-11
GO:0035645	enteric smooth muscle cell differentiation	1.183310e-10
GO:0007497	posterior midgut development	1.183310e-10
GO:0002376	immune system process	1.472516e-10
GO:0010822	positive regulation of mitochondrion organization	1.621725e-10
GO:0009607	response to biotic stimulus	4.118529e-10
GO:0050727	regulation of inflammatory response	7.685553e-10
GO:0019362	pyridine nucleotide metabolic process	9.272420e-10
GO:0031667	response to nutrient levels	1.493303e-9
GO:0046496	nicotinamide nucleotide metabolic process	1.748381e-9
GO:0007584	response to nutrient	1.827805e-9
GO:0061162	establishment of monopolar cell polarity	2.414633e-9
GO:0006959	humoral immune response	3.037588e-9
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3.192750e-9
GO:0010033	response to organic substance	3.208348e-9
GO:0044130	negative regulation of growth of symbiont in host	3.707595e-9
GO:0010867	positive regulation of triglyceride biosynthetic process	7.866472e-9
GO:0032355	response to estradiol stimulus	8.944124e-9
GO:0009991	response to extracellular stimulus	1.091490e-8
GO:0050776	regulation of immune response	1.414075e-8
GO:0032846	positive regulation of homeostatic process	1.439712e-8
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.593447e-8
GO:0003008	system process	2.229734e-8
GO:0048585	negative regulation of response to stimulus	2.233667e-8
GO:0002035	brain renin-angiotensin system	2.263445e-8
GO:0035419	activation of MAPK activity involved in innate immune response	2.310997e-8
GO:0014043	negative regulation of neuron maturation	2.402404e-8
GO:0032733	positive regulation of interleukin-10 production	3.229137e-8
GO:0032879	regulation of localization	3.286037e-8
GO:0002682	regulation of immune system process	3.604809e-8
GO:0022407	regulation of cell-cell adhesion	3.647712e-8
GO:0032496	response to lipopolysaccharide	3.741475e-8
GO:0031915	positive regulation of synaptic plasticity	3.844613e-8
GO:0043627	response to estrogen stimulus	3.928827e-8
GO:0030183	B cell differentiation	4.106595e-8
GO:0006733	oxidoreduction coenzyme metabolic process	4.201747e-8
GO:0051915	induction of synaptic plasticity by chemical substance	5.197410e-8
GO:0048545	response to steroid hormone stimulus	6.542781e-8
GO:0002830	positive regulation of type 2 immune response	8.447470e-8
GO:0019441	tryptophan catabolic process to kynurenine	9.177304e-8
GO:0002377	immunoglobulin production	1.018850e-7
GO:0002237	response to molecule of bacterial origin	1.046006e-7
GO:0002449	lymphocyte mediated immunity	1.081963e-7
GO:0030595	leukocyte chemotaxis	1.145499e-7
GO:0002016	regulation of blood volume by renin-angiotensin	1.159111e-7
GO:0048676	axon extension involved in development	1.548407e-7
GO:0051901	positive regulation of mitochondrial depolarization	1.711241e-7
GO:0050778	positive regulation of immune response	1.947047e-7
GO:0046483	heterocycle metabolic process	1.984147e-7
GO:0042113	B cell activation	2.104421e-7
GO:0006952	defense response	2.705114e-7
GO:0006568	tryptophan metabolic process	2.793792e-7
GO:0002440	production of molecular mediator of immune response	3.067865e-7
GO:0032653	regulation of interleukin-10 production	3.105822e-7
GO:0002253	activation of immune response	3.209156e-7
GO:0017085	response to insecticide	3.419334e-7
GO:0051384	response to glucocorticoid stimulus	3.561446e-7
GO:0042742	defense response to bacterium	3.860728e-7
GO:0003013	circulatory system process	4.088590e-7
GO:0019674	NAD metabolic process	4.207237e-7
GO:0043901	negative regulation of multi-organism process	4.519053e-7
GO:0051049	regulation of transport	5.277398e-7
GO:0048662	negative regulation of smooth muscle cell proliferation	5.365667e-7
GO:0032501	multicellular organismal process	6.356580e-7
GO:0009750	response to fructose stimulus	6.488931e-7
GO:0008217	regulation of blood pressure	6.666095e-7
GO:0009743	response to carbohydrate stimulus	6.667296e-7
GO:0000238	zygotene	7.083831e-7
GO:0003051	angiotensin-mediated drinking behavior	7.116906e-7
GO:0006732	coenzyme metabolic process	1.114015e-6
GO:0002684	positive regulation of immune system process	1.136770e-6
GO:0010866	regulation of triglyceride biosynthetic process	1.142974e-6
GO:0001878	response to yeast	1.151058e-6
GO:0009725	response to hormone stimulus	1.180907e-6
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.237998e-6
GO:0009306	protein secretion	1.290169e-6
GO:0008015	blood circulation	1.304911e-6
GO:0030010	establishment of cell polarity	1.311768e-6
GO:0010043	response to zinc ion	1.387097e-6
GO:0003018	vascular process in circulatory system	1.552956e-6
GO:0002700	regulation of production of molecular mediator of immune response	1.565754e-6
GO:0047497	mitochondrion transport along microtubule	1.777160e-6
GO:0031960	response to corticosteroid stimulus	1.779812e-6
GO:0017144	drug metabolic process	1.860260e-6
GO:0045807	positive regulation of endocytosis	1.869132e-6
GO:0048588	developmental cell growth	1.950714e-6
GO:0002819	regulation of adaptive immune response	2.143558e-6
GO:2000110	negative regulation of macrophage apoptosis	2.156663e-6
GO:0007154	cell communication	2.253823e-6
GO:0007166	cell surface receptor linked signaling pathway	2.299613e-6
GO:0001775	cell activation	2.401246e-6
GO:0055091	phospholipid homeostasis	2.403282e-6
GO:0033189	response to vitamin A	2.418837e-6
GO:0002250	adaptive immune response	3.548780e-6
GO:0051900	regulation of mitochondrial depolarization	3.667190e-6
GO:0006950	response to stress	3.841913e-6
GO:0009719	response to endogenous stimulus	4.249450e-6
GO:0050865	regulation of cell activation	4.506207e-6
GO:0070189	kynurenine metabolic process	4.745595e-6
GO:0051716	cellular response to stimulus	5.135694e-6
GO:0051654	establishment of mitochondrion localization	5.221105e-6
GO:0032101	regulation of response to external stimulus	5.294641e-6
GO:0009117	nucleotide metabolic process	5.351000e-6
GO:0060326	cell chemotaxis	5.360052e-6
GO:0045416	positive regulation of interleukin-8 biosynthetic process	5.404610e-6
GO:0031347	regulation of defense response	5.697576e-6
GO:0010942	positive regulation of cell death	5.781512e-6
GO:0002694	regulation of leukocyte activation	5.888669e-6
GO:0007586	digestion	6.265432e-6
GO:0055086	nucleobase-containing small molecule metabolic process	6.487295e-6
GO:0019731	antibacterial humoral response	6.528894e-6
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	6.646852e-6
GO:0045321	leukocyte activation	6.692753e-6
GO:0035644	phosphoanandamide dephosphorylation	6.936976e-6
GO:2000107	negative regulation of leukocyte apoptosis	7.174212e-6
GO:0032844	regulation of homeostatic process	7.700974e-6
GO:0001990	regulation of systemic arterial blood pressure by hormone	7.964961e-6
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	8.546307e-6
GO:0071496	cellular response to external stimulus	9.675846e-6
GO:0042493	response to drug	9.709911e-6
GO:0050880	regulation of blood vessel size	9.957473e-6
GO:0043549	regulation of kinase activity	1.035934e-5
GO:0001867	complement activation, lectin pathway	1.071309e-5
GO:0035150	regulation of tube size	1.075992e-5
GO:0050764	regulation of phagocytosis	1.218635e-5
GO:0070542	response to fatty acid	1.244087e-5
GO:0048675	axon extension	1.306573e-5
GO:0002702	positive regulation of production of molecular mediator of immune response	1.308216e-5
GO:0009968	negative regulation of signal transduction	1.312102e-5
GO:0051649	establishment of localization in cell	1.331766e-5
GO:0065008	regulation of biological quality	1.432107e-5
GO:0031334	positive regulation of protein complex assembly	1.447977e-5
GO:0031000	response to caffeine	1.516525e-5
GO:0009074	aromatic amino acid family catabolic process	1.535592e-5
GO:0051338	regulation of transferase activity	1.602580e-5
GO:0051186	cofactor metabolic process	1.636413e-5
GO:0023052	signaling	1.666377e-5
GO:0042325	regulation of phosphorylation	1.679352e-5
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.697151e-5
GO:0032722	positive regulation of chemokine production	1.737466e-5
GO:0051234	establishment of localization	1.739703e-5
GO:0006812	cation transport	1.843362e-5
GO:0009651	response to salt stress	1.945048e-5
GO:0014041	regulation of neuron maturation	1.977120e-5
GO:0034762	regulation of transmembrane transport	2.048181e-5
GO:0030001	metal ion transport	2.057152e-5
GO:0050900	leukocyte migration	2.179440e-5
GO:0061084	negative regulation of protein refolding	2.216602e-5
GO:0060555	induction of necroptosis by extracellular signals	2.233308e-5
GO:0055085	transmembrane transport	2.233492e-5
GO:0008366	axon ensheathment	2.304355e-5
GO:0014826	vein smooth muscle contraction	2.342616e-5
GO:0014829	vascular smooth muscle contraction	2.357034e-5
GO:0051103	DNA ligation involved in DNA repair	2.409634e-5
GO:0019228	regulation of action potential in neuron	2.462022e-5
GO:0032868	response to insulin stimulus	2.548859e-5
GO:0045333	cellular respiration	2.758884e-5
GO:0045576	mast cell activation	2.823638e-5
GO:0006970	response to osmotic stress	2.835340e-5
GO:0051249	regulation of lymphocyte activation	2.869809e-5
GO:0048305	immunoglobulin secretion	2.901853e-5
GO:0010821	regulation of mitochondrion organization	2.930210e-5
GO:0007229	integrin-mediated signaling pathway	2.979833e-5
GO:0002034	regulation of blood vessel size by renin-angiotensin	3.055992e-5
GO:0001932	regulation of protein phosphorylation	3.163310e-5
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	3.165330e-5
GO:0002149	hypochlorous acid biosynthetic process	3.249904e-5
GO:0032273	positive regulation of protein polymerization	3.249910e-5
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	3.283841e-5
GO:0002637	regulation of immunoglobulin production	3.334686e-5
GO:0071594	thymocyte aggregation	3.492856e-5
GO:0043434	response to peptide hormone stimulus	3.531233e-5
GO:0051179	localization	3.685465e-5
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	3.851599e-5
GO:0042552	myelination	3.860422e-5
GO:0000902	cell morphogenesis	3.937973e-5
GO:0030890	positive regulation of B cell proliferation	4.060395e-5
GO:0072376	protein activation cascade	4.115313e-5
GO:0051646	mitochondrion localization	4.150065e-5
GO:0050729	positive regulation of inflammatory response	4.383162e-5
GO:0070374	positive regulation of ERK1 and ERK2 cascade	4.764963e-5
GO:0006810	transport	4.914329e-5
GO:0001934	positive regulation of protein phosphorylation	5.035432e-5
GO:0022010	central nervous system myelination	5.117456e-5
GO:0019363	pyridine nucleotide biosynthetic process	5.155740e-5
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	5.234759e-5
GO:0070887	cellular response to chemical stimulus	5.251892e-5
GO:0009636	response to toxin	5.309484e-5
GO:0006207	'de novo' pyrimidine base biosynthetic process	5.386736e-5
GO:0071375	cellular response to peptide hormone stimulus	5.398696e-5
GO:0032675	regulation of interleukin-6 production	5.608320e-5
GO:0032765	positive regulation of mast cell cytokine production	5.734913e-5
GO:0002431	Fc receptor mediated stimulatory signaling pathway	5.734913e-5
GO:0002444	myeloid leukocyte mediated immunity	5.794552e-5
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	5.873007e-5
GO:0034220	ion transmembrane transport	6.038458e-5
GO:0001817	regulation of cytokine production	6.065552e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	6.142016e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	6.142016e-5
GO:0032707	negative regulation of interleukin-23 production	6.142016e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	6.142016e-5
GO:0043388	positive regulation of DNA binding	6.162646e-5
GO:0006811	ion transport	6.272693e-5
GO:0043068	positive regulation of programmed cell death	6.286647e-5
GO:0042127	regulation of cell proliferation	6.325306e-5
GO:0051531	NFAT protein import into nucleus	6.426921e-5
GO:0010940	positive regulation of necrotic cell death	6.426921e-5
GO:0006956	complement activation	6.564535e-5
GO:0035458	cellular response to interferon-beta	6.749313e-5
GO:0010648	negative regulation of cell communication	6.971907e-5
GO:0046684	response to pyrethroid	7.106934e-5
GO:0006586	indolalkylamine metabolic process	7.135091e-5
GO:0007165	signal transduction	7.347112e-5
GO:0043550	regulation of lipid kinase activity	7.477513e-5
GO:0048519	negative regulation of biological process	7.555838e-5
GO:0009125	nucleoside monophosphate catabolic process	7.642182e-5
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.756863e-5
GO:0050877	neurological system process	8.196051e-5
GO:0050830	defense response to Gram-positive bacterium	8.303324e-5
GO:0030002	cellular anion homeostasis	8.417823e-5
GO:0050766	positive regulation of phagocytosis	8.537568e-5
GO:0023051	regulation of signaling	8.750262e-5
GO:0033273	response to vitamin	8.843356e-5
GO:0014074	response to purine-containing compound	8.957425e-5
GO:0002761	regulation of myeloid leukocyte differentiation	9.017208e-5
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	9.193129e-5
GO:0055081	anion homeostasis	9.287188e-5
GO:0048246	macrophage chemotaxis	9.298536e-5
GO:0033152	immunoglobulin V(D)J recombination	9.339413e-5
GO:0006631	fatty acid metabolic process	9.541007e-5
GO:0023057	negative regulation of signaling	9.597829e-5
GO:0010623	developmental programmed cell death	9.642660e-5
GO:0009620	response to fungus	9.676352e-5
GO:0014012	peripheral nervous system axon regeneration	9.895544e-5
GO:0046092	deoxycytidine metabolic process	9.942093e-5
GO:0043065	positive regulation of apoptosis	9.993189e-5
GO:0007026	negative regulation of microtubule depolymerization	1.002770e-4
GO:0006266	DNA ligation	1.032800e-4
GO:0043558	regulation of translational initiation in response to stress	1.038847e-4
GO:0032989	cellular component morphogenesis	1.043380e-4
GO:0019220	regulation of phosphate metabolic process	1.076932e-4
GO:0070265	necrotic cell death	1.109463e-4
GO:0042311	vasodilation	1.121815e-4
GO:0070229	negative regulation of lymphocyte apoptosis	1.134963e-4
GO:0031114	regulation of microtubule depolymerization	1.153771e-4
GO:0048484	enteric nervous system development	1.157280e-4
GO:0032870	cellular response to hormone stimulus	1.174609e-4
GO:0042360	vitamin E metabolic process	1.188471e-4
GO:0002508	central tolerance induction	1.188471e-4
GO:0002897	positive regulation of central B cell tolerance induction	1.188471e-4
GO:0034765	regulation of ion transmembrane transport	1.222168e-4
GO:0009746	response to hexose stimulus	1.223574e-4
GO:0009612	response to mechanical stimulus	1.230084e-4
GO:0050863	regulation of T cell activation	1.241290e-4
GO:0002697	regulation of immune effector process	1.301271e-4
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.325482e-4
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.336809e-4
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.336809e-4
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.340726e-4
GO:0050832	defense response to fungus	1.340726e-4
GO:0046889	positive regulation of lipid biosynthetic process	1.341827e-4
GO:0032869	cellular response to insulin stimulus	1.459541e-4
GO:0007631	feeding behavior	1.462523e-4
GO:0032387	negative regulation of intracellular transport	1.465902e-4
GO:0048013	ephrin receptor signaling pathway	1.520130e-4
GO:0048583	regulation of response to stimulus	1.569361e-4
GO:0046112	nucleobase biosynthetic process	1.572983e-4
GO:0016074	snoRNA metabolic process	1.576973e-4
GO:0031223	auditory behavior	1.594261e-4
GO:2000036	regulation of stem cell maintenance	1.621833e-4
GO:0050663	cytokine secretion	1.621833e-4
GO:0002446	neutrophil mediated immunity	1.621833e-4
GO:0010716	negative regulation of extracellular matrix disassembly	1.625446e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.653240e-4
GO:0043269	regulation of ion transport	1.655202e-4
GO:0046907	intracellular transport	1.701366e-4
GO:0032661	regulation of interleukin-18 production	1.731806e-4
GO:0030643	cellular phosphate ion homeostasis	1.735877e-4
GO:0048518	positive regulation of biological process	1.761912e-4
GO:0043543	protein acylation	1.776067e-4
GO:0090199	regulation of release of cytochrome c from mitochondria	1.800879e-4
GO:0007163	establishment or maintenance of cell polarity	1.819318e-4
GO:0051641	cellular localization	1.841857e-4
GO:0015837	amine transport	1.859921e-4
GO:0048523	negative regulation of cellular process	1.870142e-4
GO:0002274	myeloid leukocyte activation	1.873122e-4
GO:0034284	response to monosaccharide stimulus	1.888068e-4
GO:0048790	maintenance of presynaptic active zone structure	1.901250e-4
GO:0001818	negative regulation of cytokine production	1.932593e-4
GO:0090066	regulation of anatomical structure size	1.949855e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	2.066530e-4
GO:0046813	virion attachment, binding of host cell surface receptor	2.118017e-4
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	2.118017e-4
GO:0002635	negative regulation of germinal center formation	2.118017e-4
GO:0072384	organelle transport along microtubule	2.125983e-4
GO:0050866	negative regulation of cell activation	2.135294e-4
GO:0044419	interspecies interaction between organisms	2.165869e-4
GO:0007010	cytoskeleton organization	2.173057e-4
GO:0048660	regulation of smooth muscle cell proliferation	2.189689e-4
GO:0003254	regulation of membrane depolarization	2.210363e-4
GO:0000186	activation of MAPKK activity	2.252834e-4
GO:0045834	positive regulation of lipid metabolic process	2.292206e-4
GO:0010646	regulation of cell communication	2.346269e-4
GO:0045346	regulation of MHC class II biosynthetic process	2.362429e-4
GO:0046627	negative regulation of insulin receptor signaling pathway	2.367726e-4
GO:0006766	vitamin metabolic process	2.381019e-4
GO:0032185	septin cytoskeleton organization	2.451169e-4
GO:2000189	positive regulation of cholesterol homeostasis	2.451169e-4
GO:0045414	regulation of interleukin-8 biosynthetic process	2.499380e-4
GO:0050801	ion homeostasis	2.506968e-4
GO:0032787	monocarboxylic acid metabolic process	2.510390e-4
GO:0032944	regulation of mononuclear cell proliferation	2.531321e-4
GO:0002764	immune response-regulating signaling pathway	2.577034e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.598714e-4
GO:0031650	regulation of heat generation	2.605781e-4
GO:0051246	regulation of protein metabolic process	2.619349e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	2.639037e-4
GO:0002695	negative regulation of leukocyte activation	2.641729e-4
GO:0048856	anatomical structure development	2.702813e-4
GO:0030574	collagen catabolic process	2.711706e-4
GO:0009072	aromatic amino acid family metabolic process	2.711706e-4
GO:0030162	regulation of proteolysis	2.771797e-4
GO:0019216	regulation of lipid metabolic process	2.790381e-4
GO:0055024	regulation of cardiac muscle tissue development	2.812276e-4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	2.812865e-4
GO:0050670	regulation of lymphocyte proliferation	2.896921e-4
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	2.926088e-4
GO:0031113	regulation of microtubule polymerization	2.942378e-4
GO:0019730	antimicrobial humoral response	3.043856e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.084026e-4
GO:0030888	regulation of B cell proliferation	3.106324e-4
GO:0042327	positive regulation of phosphorylation	3.175843e-4
GO:0051851	modification by host of symbiont morphology or physiology	3.178515e-4
GO:0034725	DNA replication-dependent nucleosome disassembly	3.243765e-4
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	3.243765e-4
GO:2000363	positive regulation of prostaglandin-E synthase activity	3.243765e-4
GO:0071608	macrophage inflammatory protein-1 alpha production	3.243765e-4
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	3.243765e-4
GO:0032498	detection of muramyl dipeptide	3.243765e-4
GO:0032701	negative regulation of interleukin-18 production	3.243765e-4
GO:0014056	regulation of acetylcholine secretion	3.301628e-4
GO:0016197	endosome transport	3.474699e-4
GO:0002720	positive regulation of cytokine production involved in immune response	3.484398e-4
GO:0002673	regulation of acute inflammatory response	3.562293e-4
GO:0010939	regulation of necrotic cell death	3.570694e-4
GO:0007638	mechanosensory behavior	3.678935e-4
GO:0008286	insulin receptor signaling pathway	3.745054e-4
GO:0032570	response to progesterone stimulus	3.747638e-4
GO:0000072	M phase specific microtubule process	3.749315e-4
GO:0002903	negative regulation of B cell apoptosis	3.791296e-4
GO:0002757	immune response-activating signal transduction	3.834525e-4
GO:0031112	positive regulation of microtubule polymerization or depolymerization	3.879503e-4
GO:0043966	histone H3 acetylation	3.905328e-4
GO:0006576	cellular biogenic amine metabolic process	3.906325e-4
GO:0090193	positive regulation of glomerulus development	3.998457e-4
GO:0070663	regulation of leukocyte proliferation	4.025315e-4
GO:0050790	regulation of catalytic activity	4.032979e-4
GO:0032147	activation of protein kinase activity	4.111986e-4
GO:0032763	regulation of mast cell cytokine production	4.114051e-4
GO:0035023	regulation of Rho protein signal transduction	4.134437e-4
GO:0032502	developmental process	4.231663e-4
GO:0072274	metanephric glomerular basement membrane development	4.272611e-4
GO:0072249	metanephric glomerular visceral epithelial cell development	4.272611e-4
GO:0061015	snRNA import into nucleus	4.272611e-4
GO:0048677	axon extension involved in regeneration	4.272611e-4
GO:0065009	regulation of molecular function	4.291864e-4
GO:0051023	regulation of immunoglobulin secretion	4.362927e-4
GO:2000736	regulation of stem cell differentiation	4.462827e-4
GO:0006935	chemotaxis	4.467262e-4
GO:0070278	extracellular matrix constituent secretion	4.535020e-4
GO:0002693	positive regulation of cellular extravasation	4.535020e-4
GO:0010260	organ senescence	4.535020e-4
GO:0045348	positive regulation of MHC class II biosynthetic process	4.567382e-4
GO:0010970	microtubule-based transport	4.576675e-4
GO:0071593	lymphocyte aggregation	4.600922e-4
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	4.600922e-4
GO:0016573	histone acetylation	4.613453e-4
GO:0007167	enzyme linked receptor protein signaling pathway	4.641455e-4
GO:0002426	immunoglobulin production in mucosal tissue	4.641676e-4
GO:0051702	interaction with symbiont	4.653191e-4
GO:0033151	V(D)J recombination	4.668316e-4
GO:0031399	regulation of protein modification process	4.678621e-4
GO:0006775	fat-soluble vitamin metabolic process	4.736557e-4
GO:0002064	epithelial cell development	4.757366e-4
GO:0009214	cyclic nucleotide catabolic process	4.808586e-4
GO:0006633	fatty acid biosynthetic process	4.971367e-4
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	4.987189e-4
GO:0043900	regulation of multi-organism process	5.025496e-4
GO:0060043	regulation of cardiac muscle cell proliferation	5.034173e-4
GO:0070602	regulation of centromeric sister chromatid cohesion	5.069081e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	5.069081e-4
GO:0061181	regulation of chondrocyte development	5.120381e-4
GO:0002906	negative regulation of mature B cell apoptosis	5.151708e-4
GO:0010638	positive regulation of organelle organization	5.167933e-4
GO:0030098	lymphocyte differentiation	5.177208e-4
GO:0045368	positive regulation of interleukin-13 biosynthetic process	5.200556e-4
GO:0050868	negative regulation of T cell activation	5.232811e-4
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	5.275500e-4
GO:0042297	vocal learning	5.275500e-4
GO:0007034	vacuolar transport	5.391461e-4
GO:0014823	response to activity	5.465192e-4
GO:0042330	taxis	5.477664e-4
GO:0002889	regulation of immunoglobulin mediated immune response	5.600191e-4
GO:0071260	cellular response to mechanical stimulus	5.716492e-4
GO:0042756	drinking behavior	5.756655e-4
GO:0045087	innate immune response	5.783563e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	5.826136e-4
GO:0044270	cellular nitrogen compound catabolic process	5.841926e-4
GO:0002828	regulation of type 2 immune response	5.851959e-4
GO:0006882	cellular zinc ion homeostasis	5.902700e-4
GO:0002521	leukocyte differentiation	5.952280e-4
GO:0055021	regulation of cardiac muscle tissue growth	6.076461e-4
GO:0045670	regulation of osteoclast differentiation	6.078556e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	6.106816e-4
GO:0031103	axon regeneration	6.277145e-4
GO:0015813	L-glutamate transport	6.297484e-4
GO:0030100	regulation of endocytosis	6.383555e-4
GO:0051250	negative regulation of lymphocyte activation	6.405173e-4
GO:0007032	endosome organization	6.564165e-4
GO:0051873	killing by host of symbiont cells	6.564303e-4
GO:0006739	NADP metabolic process	6.566426e-4
GO:0045859	regulation of protein kinase activity	6.580029e-4
GO:0032462	regulation of protein homooligomerization	6.636560e-4
GO:0046942	carboxylic acid transport	6.664329e-4
GO:0009628	response to abiotic stimulus	6.712465e-4
GO:0051101	regulation of DNA binding	6.729488e-4
GO:0010661	positive regulation of muscle cell apoptosis	6.741529e-4
GO:0007141	male meiosis I	6.741529e-4
GO:0006098	pentose-phosphate shunt	6.829849e-4
GO:0042119	neutrophil activation	6.940095e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	7.075984e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	7.075984e-4
GO:0006824	cobalt ion transport	7.075984e-4
GO:0032202	telomere assembly	7.094467e-4
GO:0046890	regulation of lipid biosynthetic process	7.183914e-4
GO:0042384	cilium assembly	7.187940e-4
GO:0031349	positive regulation of defense response	7.337543e-4
GO:0016049	cell growth	7.372624e-4
GO:0018393	internal peptidyl-lysine acetylation	7.385238e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	7.517550e-4
GO:0032755	positive regulation of interleukin-6 production	7.525436e-4
GO:0010040	response to iron(II) ion	7.541380e-4
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	7.541380e-4
GO:0048630	skeletal muscle tissue growth	7.541380e-4
GO:0046649	lymphocyte activation	7.721106e-4
GO:0033993	response to lipid	7.840914e-4
GO:0070309	lens fiber cell morphogenesis	7.888174e-4
GO:0070970	interleukin-2 secretion	7.927149e-4
GO:0070236	negative regulation of activation-induced cell death of T cells	7.927149e-4
GO:0002366	leukocyte activation involved in immune response	8.101232e-4
GO:0043171	peptide catabolic process	8.202004e-4
GO:0032102	negative regulation of response to external stimulus	8.266734e-4
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	8.276361e-4
GO:0052548	regulation of endopeptidase activity	8.322279e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	8.356986e-4
GO:0046058	cAMP metabolic process	8.392692e-4
GO:0071214	cellular response to abiotic stimulus	8.483705e-4
GO:0071705	nitrogen compound transport	8.493574e-4
GO:0035249	synaptic transmission, glutamatergic	8.515657e-4
GO:0044243	multicellular organismal catabolic process	8.521945e-4
GO:0040008	regulation of growth	8.692539e-4
GO:0034121	regulation of toll-like receptor signaling pathway	8.746037e-4
GO:0034143	regulation of toll-like receptor 4 signaling pathway	9.079995e-4
GO:0018394	peptidyl-lysine acetylation	9.125372e-4
GO:0015849	organic acid transport	9.154122e-4
GO:0006288	base-excision repair, DNA ligation	9.180201e-4
GO:0048678	response to axon injury	9.582669e-4
GO:0070838	divalent metal ion transport	9.649390e-4
GO:0060452	positive regulation of cardiac muscle contraction	9.721387e-4
GO:2000188	regulation of cholesterol homeostasis	9.771650e-4
GO:0051239	regulation of multicellular organismal process	9.821828e-4
GO:0031620	regulation of fever generation	9.865545e-4
GO:0050808	synapse organization	9.895893e-4
GO:0022408	negative regulation of cell-cell adhesion	9.936514e-4
GO:0032459	regulation of protein oligomerization	1.008430e-3
GO:0051128	regulation of cellular component organization	1.009326e-3
GO:0060341	regulation of cellular localization	1.011169e-3
GO:0000041	transition metal ion transport	1.020285e-3
GO:0050864	regulation of B cell activation	1.046674e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1.076896e-3
GO:0044205	'de novo' UMP biosynthetic process	1.079084e-3
GO:0010536	positive regulation of activation of Janus kinase activity	1.079084e-3
GO:0050728	negative regulation of inflammatory response	1.082835e-3
GO:2000425	regulation of apoptotic cell clearance	1.088467e-3
GO:0050771	negative regulation of axonogenesis	1.095731e-3
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.098514e-3
GO:0001889	liver development	1.109802e-3
GO:0002676	regulation of chronic inflammatory response	1.121128e-3
GO:0033674	positive regulation of kinase activity	1.125652e-3
GO:0006650	glycerophospholipid metabolic process	1.140130e-3