Coexpression cluster:C144: Difference between revisions
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{{Coexpression_clusters | {{Coexpression_clusters | ||
|full_id=C144_CD4_tonsil_NK_appendix_CD8_splenic_mycosis | |full_id=C144_CD4_tonsil_NK_appendix_CD8_splenic_mycosis | ||
|gostat_on_coexpression_clusters=GO:0002440!production of molecular mediator of immune response!0.00683967092024917!3565;50943$GO:0006417!regulation of translation!0.00683967092024917!5045;3565;50943$GO:0002573!myeloid leukocyte differentiation!0.00683967092024917!1435;3565$GO:0031326!regulation of cellular biosynthetic process!0.00683967092024917!5045;3565;50943$GO:0042129!regulation of T cell proliferation!0.00683967092024917!3565;50943$GO:0009889!regulation of biosynthetic process!0.00683967092024917!5045;3565;50943$GO:0042098!T cell proliferation!0.00683967092024917!3565;50943$GO:0017148!negative regulation of translation!0.00683967092024917!5045;50943$GO:0032944!regulation of mononuclear cell proliferation!0.00683967092024917!3565;50943$GO:0050670!regulation of lymphocyte proliferation!0.00683967092024917!3565;50943$GO:0031327!negative regulation of cellular biosynthetic process!0.00683967092024917!5045;50943$GO:0009890!negative regulation of biosynthetic process!0.00683967092024917!5045;50943$GO:0002376!immune system process!0.00683967092024917!1435;7850;3565;50943;1235$GO:0032943!mononuclear cell proliferation!0.00683967092024917!3565;50943$GO:0046651!lymphocyte proliferation!0.00683967092024917!3565;50943$GO:0050863!regulation of T cell activation!0.00683967092024917!3565;50943$GO:0042089!cytokine biosynthetic process!0.00683967092024917!3565;50943$GO:0042107!cytokine metabolic process!0.00683967092024917!3565;50943$GO:0005157!macrophage colony stimulating factor receptor binding!0.00683967092024917!1435$GO:0032693!negative regulation of interleukin-10 production!0.00683967092024917!50943$GO:0050164!oxoglutarate dehydrogenase (NADP+) activity!0.00683967092024917!4967$GO:0032689!negative regulation of interferon-gamma production!0.00683967092024917!50943$GO:0032673!regulation of interleukin-4 production!0.00683967092024917!50943$GO:0032601!connective tissue growth factor production!0.00683967092024917!3565$GO:0005136!interleukin-4 receptor binding!0.00683967092024917!3565$GO:0004276!furin activity!0.00683967092024917!5045$GO:0002725!negative regulation of T cell cytokine production!0.00683967092024917!50943$GO:0032713!negative regulation of interleukin-4 production!0.00683967092024917!50943$GO:0045189!connective tissue growth factor biosynthetic process!0.00683967092024917!3565$GO:0051525!NFAT protein binding!0.00683967092024917!50943$GO:0032804!negative regulation of low-density lipoprotein receptor catabolic process!0.00683967092024917!5045$GO:0046007!negative regulation of activated T cell proliferation!0.00683967092024917!50943$GO:0006968!cellular defense response!0.00683967092024917!3565;1235$GO:0002449!lymphocyte mediated immunity!0.00683967092024917!3565;50943$GO:0002250!adaptive immune response!0.00699486912992422!3565;50943$GO:0002460!adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains!0.00699486912992422!3565;50943$GO:0051249!regulation of lymphocyte activation!0.00699486912992422!3565;50943$GO:0030099!myeloid cell differentiation!0.00699486912992422!1435;3565$GO:0002443!leukocyte mediated immunity!0.00699486912992422!3565;50943$GO:0050865!regulation of cell activation!0.00717289543612794!3565;50943$GO:0002521!leukocyte differentiation!0.00774819298077369!1435;3565$GO:0051246!regulation of protein metabolic process!0.00774819298077369!5045;3565;50943$GO:0042110!T cell activation!0.00774819298077369!3565;50943$GO:0050776!regulation of immune response!0.00774819298077369!3565;50943$GO:0019955!cytokine binding!0.00774819298077369!7850;1235$GO:0002682!regulation of immune system process!0.00774819298077369!3565;50943$GO:0032653!regulation of interleukin-10 production!0.00774819298077369!50943$GO:0004910!interleukin-1, Type II, blocking receptor activity!0.00774819298077369!7850$GO:0032803!regulation of low-density lipoprotein receptor catabolic process!0.00774819298077369!5045$GO:0002704!negative regulation of leukocyte mediated immunity!0.00774819298077369!50943$GO:0032703!negative regulation of interleukin-2 production!0.00774819298077369!50943$GO:0032801!receptor catabolic process!0.00774819298077369!5045$GO:0002710!negative regulation of T cell mediated immunity!0.00774819298077369!50943$GO:0048295!positive regulation of isotype switching to IgE isotypes!0.00774819298077369!3565$GO:0002707!negative regulation of lymphocyte mediated immunity!0.00774819298077369!50943$GO:0032802!low-density lipoprotein receptor catabolic process!0.00774819298077369!5045$GO:0032792!inhibition of CREB transcription factor!0.00774819298077369!50943$GO:0019968!interleukin-1, Type II, blocking binding!0.00774819298077369!7850$GO:0051248!negative regulation of protein metabolic process!0.00819216705586183!5045;50943$GO:0042127!regulation of cell proliferation!0.00885534337479167!1435;3565;50943$GO:0002252!immune effector process!0.00885534337479167!3565;50943$GO:0001816!cytokine production!0.0090803420662768!3565;50943$GO:0042592!homeostatic process!0.0090803420662768!9990;50943;1235$GO:0032799!low-density lipoprotein receptor metabolic process!0.00949230836421774!5045$GO:0048289!isotype switching to IgE isotypes!0.00949230836421774!3565$GO:0002701!negative regulation of production of molecular mediator of immune response!0.00949230836421774!50943$GO:0016565!general transcriptional repressor activity!0.00949230836421774!50943$GO:0048293!regulation of isotype switching to IgE isotypes!0.00949230836421774!3565$GO:0045085!negative regulation of interleukin-2 biosynthetic process!0.00949230836421774!50943$GO:0048304!positive regulation of isotype switching to IgG isotypes!0.00949230836421774!3565$GO:0002719!negative regulation of cytokine production during immune response!0.00949230836421774!50943$GO:0006955!immune response!0.0105740373439106!7850;3565;50943;1235$GO:0050710!negative regulation of cytokine secretion!0.0113544630907996!50943$GO:0048302!regulation of isotype switching to IgG isotypes!0.0113544630907996!3565$GO:0015379!potassium:chloride symporter activity!0.0113544630907996!9990$GO:0032633!interleukin-4 production!0.0113544630907996!50943$GO:0002698!negative regulation of immune effector process!0.0113544630907996!50943$GO:0032088!inhibition of NF-kappaB transcription factor!0.0113544630907996!50943$GO:0048291!isotype switching to IgG isotypes!0.0113544630907996!3565$GO:0042330!taxis!0.0113544630907996!3565;1235$GO:0006935!chemotaxis!0.0113544630907996!3565;1235$GO:0046649!lymphocyte activation!0.01275901911404!3565;50943$GO:0002820!negative regulation of adaptive immune response!0.01275901911404!50943$GO:0002369!T cell cytokine production!0.01275901911404!50943$GO:0032613!interleukin-10 production!0.01275901911404!50943$GO:0045348!positive regulation of MHC class II biosynthetic process!0.01275901911404!3565$GO:0002823!negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains!0.01275901911404!50943$GO:0002724!regulation of T cell cytokine production!0.01275901911404!50943$GO:0030097!hemopoiesis!0.0128714643838124!1435;3565$GO:0048534!hemopoietic or lymphoid organ development!0.0136068165663078!1435;3565$GO:0045342!MHC class II biosynthetic process!0.0136068165663078!3565$GO:0045830!positive regulation of isotype switching!0.0136068165663078!3565$GO:0045346!regulation of MHC class II biosynthetic process!0.0136068165663078!3565$GO:0002709!regulation of T cell mediated immunity!0.0136068165663078!50943$GO:0050709!negative regulation of protein secretion!0.0136068165663078!50943$GO:0006884!regulation of cell volume!0.0136068165663078!9990$GO:0043029!T cell homeostasis!0.0136068165663078!50943$GO:0032663!regulation of interleukin-2 production!0.0136068165663078!50943$GO:0032649!regulation of interferon-gamma production!0.0136068165663078!50943$GO:0045321!leukocyte activation!0.0142592197625642!3565;50943$GO:0007626!locomotory behavior!0.0142721472839673!3565;1235$GO:0002520!immune system development!0.0142856100530098!1435;3565$GO:0046006!regulation of activated T cell proliferation!0.0148232410809889!50943$GO:0045671!negative regulation of osteoclast differentiation!0.0148232410809889!3565$GO:0004591!oxoglutarate dehydrogenase (succinyl-transferring) activity!0.0148232410809889!4967$GO:0050798!activated T cell proliferation!0.0148232410809889!50943$GO:0042130!negative regulation of T cell proliferation!0.0166237024164733!50943$GO:0004908!interleukin-1 receptor activity!0.0166237024164733!7850$GO:0001775!cell activation!0.0167419623278427!3565;50943$GO:0008283!cell proliferation!0.0167419623278427!1435;3565;50943$GO:0002718!regulation of cytokine production during immune response!0.0167419623278427!50943$GO:0002700!regulation of production of molecular mediator of immune response!0.0167419623278427!50943$GO:0045670!regulation of osteoclast differentiation!0.0167419623278427!3565$GO:0004945!angiotensin type II receptor activity!0.0167419623278427!1235$GO:0001595!angiotensin receptor activity!0.0167419623278427!1235$GO:0050777!negative regulation of immune response!0.0167419623278427!50943$GO:0002762!negative regulation of myeloid leukocyte differentiation!0.0167419623278427!3565$GO:0045191!regulation of isotype switching!0.0167419623278427!3565$GO:0002367!cytokine production during immune response!0.0167419623278427!50943$GO:0030890!positive regulation of B cell proliferation!0.0167419623278427!3565$GO:0065007!biological regulation!0.0167419623278427!9990;5045;1235;94039;1435;50943;3565;9882$GO:0002683!negative regulation of immune system process!0.0174971254258332!50943$GO:0042092!T-helper 2 type immune response!0.0174971254258332!3565$GO:0002456!T cell mediated immunity!0.0174971254258332!50943$GO:0019966!interleukin-1 binding!0.0174971254258332!7850$GO:0002260!lymphocyte homeostasis!0.0174971254258332!50943$GO:0001818!negative regulation of cytokine production!0.0174971254258332!50943$GO:0030888!regulation of B cell proliferation!0.0174971254258332!3565$GO:0008284!positive regulation of cell proliferation!0.0174971254258332!1435;3565$GO:0006873!cellular ion homeostasis!0.0174971254258332!9990;1235$GO:0055082!cellular chemical homeostasis!0.0174971254258332!9990;1235$GO:0043112!receptor metabolic process!0.0174971254258332!5045$GO:0030316!osteoclast differentiation!0.0174971254258332!3565$GO:0002208!somatic diversification of immunoglobulins during immune response!0.0174971254258332!3565$GO:0002381!immunoglobulin production during immune response!0.0174971254258332!3565$GO:0050868!negative regulation of T cell activation!0.0174971254258332!50943$GO:0030225!macrophage differentiation!0.0174971254258332!1435$GO:0050672!negative regulation of lymphocyte proliferation!0.0174971254258332!50943$GO:0002204!somatic recombination of immunoglobulin genes during immune response!0.0174971254258332!3565$GO:0045190!isotype switching!0.0174971254258332!3565$GO:0032945!negative regulation of mononuclear cell proliferation!0.0174971254258332!50943$GO:0002703!regulation of leukocyte mediated immunity!0.0186862618924103!50943$GO:0002706!regulation of lymphocyte mediated immunity!0.0186862618924103!50943$GO:0015377!cation:chloride symporter activity!0.0186862618924103!9990$GO:0008083!growth factor activity!0.0191008012011806!1435;3565$GO:0016447!somatic recombination of immunoglobulin gene segments!0.0196922737065576!3565$GO:0002819!regulation of adaptive immune response!0.0196922737065576!50943$GO:0002822!regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.!0.0196922737065576!50943$GO:0050801!ion homeostasis!0.0206327863999324!9990;1235$GO:0001776!leukocyte homeostasis!0.0209199940569343!50943$GO:0005515!protein binding!0.0210090596731958!5045;140691;1235;55930;1435;7850;50943;3565;55795$GO:0051239!regulation of multicellular organismal process!0.0210090596731958!3565;50943$GO:0045941!positive regulation of transcription!0.0210090596731958!3565;50943$GO:0016444!somatic cell DNA recombination!0.0210090596731958!3565$GO:0048872!homeostasis of number of cells!0.0210090596731958!50943$GO:0016445!somatic diversification of immunoglobulins!0.0210090596731958!3565$GO:0045076!regulation of interleukin-2 biosynthetic process!0.0210090596731958!50943$GO:0002697!regulation of immune effector process!0.0210090596731958!50943$GO:0002761!regulation of myeloid leukocyte differentiation!0.0210090596731958!3565$GO:0002562!somatic diversification of immune receptors via germline recombination within a single locus!0.0210090596731958!3565$GO:0045935!positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!0.0214659153375232!3565;50943$GO:0042094!interleukin-2 biosynthetic process!0.0214659153375232!50943$GO:0002200!somatic diversification of immune receptors!0.0214659153375232!3565$GO:0043433!negative regulation of transcription factor activity!0.0214659153375232!50943$GO:0006465!signal peptide processing!0.0214659153375232!5045$GO:0050707!regulation of cytokine secretion!0.0214659153375232!50943$GO:0042036!negative regulation of cytokine biosynthetic process!0.0214659153375232!50943$GO:0007610!behavior!0.022043145403191!3565;1235$GO:0051048!negative regulation of secretion!0.0225329827501509!50943$GO:0048878!chemical homeostasis!0.0226474620966088!9990;1235$GO:0065008!regulation of biological quality!0.0226474620966088!9990;50943;1235$GO:0048522!positive regulation of cellular process!0.0226474620966088!1435;3565;50943$GO:0051059!NF-kappaB binding!0.0226474620966088!50943$GO:0002377!immunoglobulin production!0.0226474620966088!3565$GO:0050871!positive regulation of B cell activation!0.0226474620966088!3565$GO:0032609!interferon-gamma production!0.0226474620966088!50943$GO:0042100!B cell proliferation!0.0226474620966088!3565$GO:0045638!negative regulation of myeloid cell differentiation!0.0226474620966088!3565$GO:0005125!cytokine activity!0.0229122396093299!1435;3565$GO:0051250!negative regulation of lymphocyte activation!0.0236351688993002!50943$GO:0050663!cytokine secretion!0.0247365777129357!50943$GO:0032623!interleukin-2 production!0.0256842556334335!50943$GO:0016624!oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor!0.0256842556334335!4967$GO:0048518!positive regulation of biological process!0.0288621617302424!1435;3565;50943$GO:0019957!C-C chemokine binding!0.0288621617302424!1235$GO:0016493!C-C chemokine receptor activity!0.0288621617302424!1235$GO:0051241!negative regulation of multicellular organismal process!0.0295234892360718!50943$GO:0042102!positive regulation of T cell proliferation!0.0295234892360718!3565$GO:0050864!regulation of B cell activation!0.0295234892360718!3565$GO:0031325!positive regulation of cellular metabolic process!0.0295234892360718!3565;50943$GO:0050708!regulation of protein secretion!0.0304362923968099!50943$GO:0019725!cellular homeostasis!0.0307627271557973!9990;1235$GO:0031324!negative regulation of cellular metabolic process!0.031543669199429!5045;50943$GO:0006518!peptide metabolic process!0.0322573951588899!5045$GO:0009893!positive regulation of metabolic process!0.032689212371392!3565;50943$GO:0048523!negative regulation of cellular process!0.032689212371392!5045;3565;50943$GO:0030183!B cell differentiation!0.032727770443523!3565$GO:0030140!trans-Golgi network transport vesicle!0.032727770443523!5045$GO:0032946!positive regulation of mononuclear cell proliferation!0.0335108540097155!3565$GO:0050671!positive regulation of lymphocyte proliferation!0.0335108540097155!3565$GO:0048519!negative regulation of biological process!0.0353893559769884!5045;3565;50943$GO:0006412!translation!0.0372036479975713!5045;3565;50943$GO:0045637!regulation of myeloid cell differentiation!0.0372036479975713!3565$GO:0004907!interleukin receptor activity!0.0372036479975713!7850$GO:0004289!subtilase activity!0.0381032136950474!5045$GO:0009892!negative regulation of metabolic process!0.0381769303645508!5045;50943$GO:0004950!chemokine receptor activity!0.0386186634662823!1235$GO:0001637!G-protein chemoattractant receptor activity!0.0386186634662823!1235$GO:0006066!alcohol metabolic process!0.0391107838973536!4967;3565$GO:0019956!chemokine binding!0.0403593060030109!1235$GO:0015296!anion:cation symporter activity!0.0410221858338763!9990$GO:0051015!actin filament binding!0.0410221858338763!55930$GO:0019965!interleukin binding!0.0418678931946746!7850$GO:0050870!positive regulation of T cell activation!0.0425066411937473!3565$GO:0001817!regulation of cytokine production!0.0425066411937473!50943 | |||
|id=C144 | |id=C144 | ||
}} | }} |
Revision as of 17:34, 18 May 2012
Full id: C144_CD4_tonsil_NK_appendix_CD8_splenic_mycosis
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0002440 | production of molecular mediator of immune response | 0.00683967092024917 |
GO:0006417 | regulation of translation | 0.00683967092024917 |
GO:0002573 | myeloid leukocyte differentiation | 0.00683967092024917 |
GO:0031326 | regulation of cellular biosynthetic process | 0.00683967092024917 |
GO:0042129 | regulation of T cell proliferation | 0.00683967092024917 |
GO:0009889 | regulation of biosynthetic process | 0.00683967092024917 |
GO:0042098 | T cell proliferation | 0.00683967092024917 |
GO:0017148 | negative regulation of translation | 0.00683967092024917 |
GO:0032944 | regulation of mononuclear cell proliferation | 0.00683967092024917 |
GO:0050670 | regulation of lymphocyte proliferation | 0.00683967092024917 |
GO:0031327 | negative regulation of cellular biosynthetic process | 0.00683967092024917 |
GO:0009890 | negative regulation of biosynthetic process | 0.00683967092024917 |
GO:0002376 | immune system process | 0.00683967092024917 |
GO:0032943 | mononuclear cell proliferation | 0.00683967092024917 |
GO:0046651 | lymphocyte proliferation | 0.00683967092024917 |
GO:0050863 | regulation of T cell activation | 0.00683967092024917 |
GO:0042089 | cytokine biosynthetic process | 0.00683967092024917 |
GO:0042107 | cytokine metabolic process | 0.00683967092024917 |
GO:0005157 | macrophage colony stimulating factor receptor binding | 0.00683967092024917 |
GO:0032693 | negative regulation of interleukin-10 production | 0.00683967092024917 |
GO:0050164 | oxoglutarate dehydrogenase (NADP+) activity | 0.00683967092024917 |
GO:0032689 | negative regulation of interferon-gamma production | 0.00683967092024917 |
GO:0032673 | regulation of interleukin-4 production | 0.00683967092024917 |
GO:0032601 | connective tissue growth factor production | 0.00683967092024917 |
GO:0005136 | interleukin-4 receptor binding | 0.00683967092024917 |
GO:0004276 | furin activity | 0.00683967092024917 |
GO:0002725 | negative regulation of T cell cytokine production | 0.00683967092024917 |
GO:0032713 | negative regulation of interleukin-4 production | 0.00683967092024917 |
GO:0045189 | connective tissue growth factor biosynthetic process | 0.00683967092024917 |
GO:0051525 | NFAT protein binding | 0.00683967092024917 |
GO:0032804 | negative regulation of low-density lipoprotein receptor catabolic process | 0.00683967092024917 |
GO:0046007 | negative regulation of activated T cell proliferation | 0.00683967092024917 |
GO:0006968 | cellular defense response | 0.00683967092024917 |
GO:0002449 | lymphocyte mediated immunity | 0.00683967092024917 |
GO:0002250 | adaptive immune response | 0.00699486912992422 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.00699486912992422 |
GO:0051249 | regulation of lymphocyte activation | 0.00699486912992422 |
GO:0030099 | myeloid cell differentiation | 0.00699486912992422 |
GO:0002443 | leukocyte mediated immunity | 0.00699486912992422 |
GO:0050865 | regulation of cell activation | 0.00717289543612794 |
GO:0002521 | leukocyte differentiation | 0.00774819298077369 |
GO:0051246 | regulation of protein metabolic process | 0.00774819298077369 |
GO:0042110 | T cell activation | 0.00774819298077369 |
GO:0050776 | regulation of immune response | 0.00774819298077369 |
GO:0019955 | cytokine binding | 0.00774819298077369 |
GO:0002682 | regulation of immune system process | 0.00774819298077369 |
GO:0032653 | regulation of interleukin-10 production | 0.00774819298077369 |
GO:0004910 | interleukin-1, Type II, blocking receptor activity | 0.00774819298077369 |
GO:0032803 | regulation of low-density lipoprotein receptor catabolic process | 0.00774819298077369 |
GO:0002704 | negative regulation of leukocyte mediated immunity | 0.00774819298077369 |
GO:0032703 | negative regulation of interleukin-2 production | 0.00774819298077369 |
GO:0032801 | receptor catabolic process | 0.00774819298077369 |
GO:0002710 | negative regulation of T cell mediated immunity | 0.00774819298077369 |
GO:0048295 | positive regulation of isotype switching to IgE isotypes | 0.00774819298077369 |
GO:0002707 | negative regulation of lymphocyte mediated immunity | 0.00774819298077369 |
GO:0032802 | low-density lipoprotein receptor catabolic process | 0.00774819298077369 |
GO:0032792 | inhibition of CREB transcription factor | 0.00774819298077369 |
GO:0019968 | interleukin-1, Type II, blocking binding | 0.00774819298077369 |
GO:0051248 | negative regulation of protein metabolic process | 0.00819216705586183 |
GO:0042127 | regulation of cell proliferation | 0.00885534337479167 |
GO:0002252 | immune effector process | 0.00885534337479167 |
GO:0001816 | cytokine production | 0.0090803420662768 |
GO:0042592 | homeostatic process | 0.0090803420662768 |
GO:0032799 | low-density lipoprotein receptor metabolic process | 0.00949230836421774 |
GO:0048289 | isotype switching to IgE isotypes | 0.00949230836421774 |
GO:0002701 | negative regulation of production of molecular mediator of immune response | 0.00949230836421774 |
GO:0016565 | general transcriptional repressor activity | 0.00949230836421774 |
GO:0048293 | regulation of isotype switching to IgE isotypes | 0.00949230836421774 |
GO:0045085 | negative regulation of interleukin-2 biosynthetic process | 0.00949230836421774 |
GO:0048304 | positive regulation of isotype switching to IgG isotypes | 0.00949230836421774 |
GO:0002719 | negative regulation of cytokine production during immune response | 0.00949230836421774 |
GO:0006955 | immune response | 0.0105740373439106 |
GO:0050710 | negative regulation of cytokine secretion | 0.0113544630907996 |
GO:0048302 | regulation of isotype switching to IgG isotypes | 0.0113544630907996 |
GO:0015379 | potassium:chloride symporter activity | 0.0113544630907996 |
GO:0032633 | interleukin-4 production | 0.0113544630907996 |
GO:0002698 | negative regulation of immune effector process | 0.0113544630907996 |
GO:0032088 | inhibition of NF-kappaB transcription factor | 0.0113544630907996 |
GO:0048291 | isotype switching to IgG isotypes | 0.0113544630907996 |
GO:0042330 | taxis | 0.0113544630907996 |
GO:0006935 | chemotaxis | 0.0113544630907996 |
GO:0046649 | lymphocyte activation | 0.01275901911404 |
GO:0002820 | negative regulation of adaptive immune response | 0.01275901911404 |
GO:0002369 | T cell cytokine production | 0.01275901911404 |
GO:0032613 | interleukin-10 production | 0.01275901911404 |
GO:0045348 | positive regulation of MHC class II biosynthetic process | 0.01275901911404 |
GO:0002823 | negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.01275901911404 |
GO:0002724 | regulation of T cell cytokine production | 0.01275901911404 |
GO:0030097 | hemopoiesis | 0.0128714643838124 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.0136068165663078 |
GO:0045342 | MHC class II biosynthetic process | 0.0136068165663078 |
GO:0045830 | positive regulation of isotype switching | 0.0136068165663078 |
GO:0045346 | regulation of MHC class II biosynthetic process | 0.0136068165663078 |
GO:0002709 | regulation of T cell mediated immunity | 0.0136068165663078 |
GO:0050709 | negative regulation of protein secretion | 0.0136068165663078 |
GO:0006884 | regulation of cell volume | 0.0136068165663078 |
GO:0043029 | T cell homeostasis | 0.0136068165663078 |
GO:0032663 | regulation of interleukin-2 production | 0.0136068165663078 |
GO:0032649 | regulation of interferon-gamma production | 0.0136068165663078 |
GO:0045321 | leukocyte activation | 0.0142592197625642 |
GO:0007626 | locomotory behavior | 0.0142721472839673 |
GO:0002520 | immune system development | 0.0142856100530098 |
GO:0046006 | regulation of activated T cell proliferation | 0.0148232410809889 |
GO:0045671 | negative regulation of osteoclast differentiation | 0.0148232410809889 |
GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 0.0148232410809889 |
GO:0050798 | activated T cell proliferation | 0.0148232410809889 |
GO:0042130 | negative regulation of T cell proliferation | 0.0166237024164733 |
GO:0004908 | interleukin-1 receptor activity | 0.0166237024164733 |
GO:0001775 | cell activation | 0.0167419623278427 |
GO:0008283 | cell proliferation | 0.0167419623278427 |
GO:0002718 | regulation of cytokine production during immune response | 0.0167419623278427 |
GO:0002700 | regulation of production of molecular mediator of immune response | 0.0167419623278427 |
GO:0045670 | regulation of osteoclast differentiation | 0.0167419623278427 |
GO:0004945 | angiotensin type II receptor activity | 0.0167419623278427 |
GO:0001595 | angiotensin receptor activity | 0.0167419623278427 |
GO:0050777 | negative regulation of immune response | 0.0167419623278427 |
GO:0002762 | negative regulation of myeloid leukocyte differentiation | 0.0167419623278427 |
GO:0045191 | regulation of isotype switching | 0.0167419623278427 |
GO:0002367 | cytokine production during immune response | 0.0167419623278427 |
GO:0030890 | positive regulation of B cell proliferation | 0.0167419623278427 |
GO:0065007 | biological regulation | 0.0167419623278427 |
GO:0002683 | negative regulation of immune system process | 0.0174971254258332 |
GO:0042092 | T-helper 2 type immune response | 0.0174971254258332 |
GO:0002456 | T cell mediated immunity | 0.0174971254258332 |
GO:0019966 | interleukin-1 binding | 0.0174971254258332 |
GO:0002260 | lymphocyte homeostasis | 0.0174971254258332 |
GO:0001818 | negative regulation of cytokine production | 0.0174971254258332 |
GO:0030888 | regulation of B cell proliferation | 0.0174971254258332 |
GO:0008284 | positive regulation of cell proliferation | 0.0174971254258332 |
GO:0006873 | cellular ion homeostasis | 0.0174971254258332 |
GO:0055082 | cellular chemical homeostasis | 0.0174971254258332 |
GO:0043112 | receptor metabolic process | 0.0174971254258332 |
GO:0030316 | osteoclast differentiation | 0.0174971254258332 |
GO:0002208 | somatic diversification of immunoglobulins during immune response | 0.0174971254258332 |
GO:0002381 | immunoglobulin production during immune response | 0.0174971254258332 |
GO:0050868 | negative regulation of T cell activation | 0.0174971254258332 |
GO:0030225 | macrophage differentiation | 0.0174971254258332 |
GO:0050672 | negative regulation of lymphocyte proliferation | 0.0174971254258332 |
GO:0002204 | somatic recombination of immunoglobulin genes during immune response | 0.0174971254258332 |
GO:0045190 | isotype switching | 0.0174971254258332 |
GO:0032945 | negative regulation of mononuclear cell proliferation | 0.0174971254258332 |
GO:0002703 | regulation of leukocyte mediated immunity | 0.0186862618924103 |
GO:0002706 | regulation of lymphocyte mediated immunity | 0.0186862618924103 |
GO:0015377 | cation:chloride symporter activity | 0.0186862618924103 |
GO:0008083 | growth factor activity | 0.0191008012011806 |
GO:0016447 | somatic recombination of immunoglobulin gene segments | 0.0196922737065576 |
GO:0002819 | regulation of adaptive immune response | 0.0196922737065576 |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 0.0196922737065576 |
GO:0050801 | ion homeostasis | 0.0206327863999324 |
GO:0001776 | leukocyte homeostasis | 0.0209199940569343 |
GO:0005515 | protein binding | 0.0210090596731958 |
GO:0051239 | regulation of multicellular organismal process | 0.0210090596731958 |
GO:0045941 | positive regulation of transcription | 0.0210090596731958 |
GO:0016444 | somatic cell DNA recombination | 0.0210090596731958 |
GO:0048872 | homeostasis of number of cells | 0.0210090596731958 |
GO:0016445 | somatic diversification of immunoglobulins | 0.0210090596731958 |
GO:0045076 | regulation of interleukin-2 biosynthetic process | 0.0210090596731958 |
GO:0002697 | regulation of immune effector process | 0.0210090596731958 |
GO:0002761 | regulation of myeloid leukocyte differentiation | 0.0210090596731958 |
GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 0.0210090596731958 |
GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0214659153375232 |
GO:0042094 | interleukin-2 biosynthetic process | 0.0214659153375232 |
GO:0002200 | somatic diversification of immune receptors | 0.0214659153375232 |
GO:0043433 | negative regulation of transcription factor activity | 0.0214659153375232 |
GO:0006465 | signal peptide processing | 0.0214659153375232 |
GO:0050707 | regulation of cytokine secretion | 0.0214659153375232 |
GO:0042036 | negative regulation of cytokine biosynthetic process | 0.0214659153375232 |
GO:0007610 | behavior | 0.022043145403191 |
GO:0051048 | negative regulation of secretion | 0.0225329827501509 |
GO:0048878 | chemical homeostasis | 0.0226474620966088 |
GO:0065008 | regulation of biological quality | 0.0226474620966088 |
GO:0048522 | positive regulation of cellular process | 0.0226474620966088 |
GO:0051059 | NF-kappaB binding | 0.0226474620966088 |
GO:0002377 | immunoglobulin production | 0.0226474620966088 |
GO:0050871 | positive regulation of B cell activation | 0.0226474620966088 |
GO:0032609 | interferon-gamma production | 0.0226474620966088 |
GO:0042100 | B cell proliferation | 0.0226474620966088 |
GO:0045638 | negative regulation of myeloid cell differentiation | 0.0226474620966088 |
GO:0005125 | cytokine activity | 0.0229122396093299 |
GO:0051250 | negative regulation of lymphocyte activation | 0.0236351688993002 |
GO:0050663 | cytokine secretion | 0.0247365777129357 |
GO:0032623 | interleukin-2 production | 0.0256842556334335 |
GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 0.0256842556334335 |
GO:0048518 | positive regulation of biological process | 0.0288621617302424 |
GO:0019957 | C-C chemokine binding | 0.0288621617302424 |
GO:0016493 | C-C chemokine receptor activity | 0.0288621617302424 |
GO:0051241 | negative regulation of multicellular organismal process | 0.0295234892360718 |
GO:0042102 | positive regulation of T cell proliferation | 0.0295234892360718 |
GO:0050864 | regulation of B cell activation | 0.0295234892360718 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0295234892360718 |
GO:0050708 | regulation of protein secretion | 0.0304362923968099 |
GO:0019725 | cellular homeostasis | 0.0307627271557973 |
GO:0031324 | negative regulation of cellular metabolic process | 0.031543669199429 |
GO:0006518 | peptide metabolic process | 0.0322573951588899 |
GO:0009893 | positive regulation of metabolic process | 0.032689212371392 |
GO:0048523 | negative regulation of cellular process | 0.032689212371392 |
GO:0030183 | B cell differentiation | 0.032727770443523 |
GO:0030140 | trans-Golgi network transport vesicle | 0.032727770443523 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0335108540097155 |
GO:0050671 | positive regulation of lymphocyte proliferation | 0.0335108540097155 |
GO:0048519 | negative regulation of biological process | 0.0353893559769884 |
GO:0006412 | translation | 0.0372036479975713 |
GO:0045637 | regulation of myeloid cell differentiation | 0.0372036479975713 |
GO:0004907 | interleukin receptor activity | 0.0372036479975713 |
GO:0004289 | subtilase activity | 0.0381032136950474 |
GO:0009892 | negative regulation of metabolic process | 0.0381769303645508 |
GO:0004950 | chemokine receptor activity | 0.0386186634662823 |
GO:0001637 | G-protein chemoattractant receptor activity | 0.0386186634662823 |
GO:0006066 | alcohol metabolic process | 0.0391107838973536 |
GO:0019956 | chemokine binding | 0.0403593060030109 |
GO:0015296 | anion:cation symporter activity | 0.0410221858338763 |
GO:0051015 | actin filament binding | 0.0410221858338763 |
GO:0019965 | interleukin binding | 0.0418678931946746 |
GO:0050870 | positive regulation of T cell activation | 0.0425066411937473 |
GO:0001817 | regulation of cytokine production | 0.0425066411937473 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.