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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C969_mature_insula_mesodermal_occipital_Preadipocyte_temporal_heart
|full_id=C969_mature_insula_mesodermal_occipital_Preadipocyte_temporal_heart
|gostat_on_coexpression_clusters=GO:0005200!structural constituent of cytoskeleton!4.99147211879799e-05!6709;83660;6711$GO:0008091!spectrin!9.70308090475593e-05!6709;6711$GO:0030864!cortical actin cytoskeleton!0.000136243055220067!6709;6711$GO:0051693!actin filament capping!0.000136243055220067!6709;6711$GO:0051016!barbed-end actin filament capping!0.000136243055220067!6709;6711$GO:0030835!negative regulation of actin filament depolymerization!0.000136243055220067!6709;6711$GO:0030834!regulation of actin filament depolymerization!0.000136243055220067!6709;6711$GO:0030042!actin filament depolymerization!0.000136243055220067!6709;6711$GO:0030863!cortical cytoskeleton!0.000143580142384078!6709;6711$GO:0015629!actin cytoskeleton!0.000213216949059869!6709;83660;6711$GO:0008064!regulation of actin polymerization and/or depolymerization!0.000290516615129923!6709;6711$GO:0044448!cell cortex part!0.000290516615129923!6709;6711$GO:0051261!protein depolymerization!0.000290516615129923!6709;6711$GO:0030832!regulation of actin filament length!0.000290516615129923!6709;6711$GO:0032535!regulation of cellular component size!0.000290516615129923!6709;6711$GO:0032956!regulation of actin cytoskeleton organization and biogenesis!0.000290516615129923!6709;6711$GO:0051129!negative regulation of cellular component organization and biogenesis!0.000335265835546014!6709;6711$GO:0051493!regulation of cytoskeleton organization and biogenesis!0.000343288446968344!6709;6711$GO:0033043!regulation of organelle organization and biogenesis!0.000343288446968344!6709;6711$GO:0003779!actin binding!0.000343288446968344!6709;83660;6711$GO:0008154!actin polymerization and/or depolymerization!0.000374299671112961!6709;6711$GO:0005938!cell cortex!0.000393507614964763!6709;6711$GO:0008092!cytoskeletal protein binding!0.000771815799853878!6709;83660;6711$GO:0051128!regulation of cellular component organization and biogenesis!0.000883182958994439!6709;6711$GO:0051248!negative regulation of protein metabolic process!0.000917108549270258!6709;6711$GO:0007010!cytoskeleton organization and biogenesis!0.00100030724883964!6709;83660;6711$GO:0005516!calmodulin binding!0.00156030768475826!6709;6711$GO:0030036!actin cytoskeleton organization and biogenesis!0.00459280999558969!6709;6711$GO:0030029!actin filament-based process!0.00488493878915314!6709;6711$GO:0043121!neurotrophin binding!0.00488493878915314!4915$GO:0048488!synaptic vesicle endocytosis!0.00567241467434988!6453$GO:0016043!cellular component organization and biogenesis!0.00573061625175347!6709;83660;6711;6453$GO:0005856!cytoskeleton!0.00662604076192401!6709;83660;6711$GO:0006996!organelle organization and biogenesis!0.00797412921710054!6709;83660;6711$GO:0007016!cytoskeletal anchoring!0.0091139899944362!83660$GO:0005886!plasma membrane!0.0091139899944362!4915;83660;6711;6453$GO:0051246!regulation of protein metabolic process!0.0100232053533945!6709;6711$GO:0030054!cell junction!0.0100807159878271!83660;6453$GO:0009892!negative regulation of metabolic process!0.0101401678185353!6709;6711$GO:0007043!intercellular junction assembly!0.0102515793004705!83660$GO:0045216!intercellular junction assembly and maintenance!0.0125492597196398!83660$GO:0048489!synaptic vesicle transport!0.0125492597196398!6453$GO:0007028!cytoplasm organization and biogenesis!0.0163360075800794!83660$GO:0044459!plasma membrane part!0.0196488111773652!4915;83660;6453$GO:0005624!membrane fraction!0.0211664538902833!6709;6453$GO:0005925!focal adhesion!0.0215907385342878!83660$GO:0005515!protein binding!0.0215907385342878!4915;6709;83660;6711;6453$GO:0019717!synaptosome!0.0219321352358375!6453$GO:0005924!cell-substrate adherens junction!0.0226747890717908!83660$GO:0030055!cell-matrix junction!0.0233873930407654!83660$GO:0001726!ruffle!0.0246430376281777!83660$GO:0005912!adherens junction!0.0302912053126019!83660$GO:0000267!cell fraction!0.0302912053126019!6709;6453$GO:0019538!protein metabolic process!0.0302912053126019!4915;6709;83660;6711$GO:0044430!cytoskeletal part!0.0302912053126019!6709;6711$GO:0043232!intracellular non-membrane-bound organelle!0.0302912053126019!6709;83660;6711$GO:0043228!non-membrane-bound organelle!0.0302912053126019!6709;83660;6711$GO:0065008!regulation of biological quality!0.0313083760599613!6709;6711$GO:0031252!leading edge!0.0355917882053961!83660$GO:0016323!basolateral plasma membrane!0.0412782857834084!83660$GO:0048523!negative regulation of cellular process!0.0417652213505117!6709;6711$GO:0019838!growth factor binding!0.0418142683574165!4915$GO:0048519!negative regulation of biological process!0.0435488653287554!6709;6711$GO:0004714!transmembrane receptor protein tyrosine kinase activity!0.0495374653713563!4915
|id=C969
|id=C969
}}
}}

Revision as of 17:42, 18 May 2012


Full id: C969_mature_insula_mesodermal_occipital_Preadipocyte_temporal_heart



Phase1 CAGE Peaks

Hg19::chr10:118502070..118502084,-p1@HSPA12A
Hg19::chr15:62682733..62682759,+p1@TLN2
Hg19::chr21:35014829..35014912,+p1@ITSN1
Hg19::chr2:54683419..54683442,+p2@SPTBN1
Hg19::chr2:54683448..54683470,+p1@SPTBN1
Hg19::chr2:54684327..54684399,+p4@SPTBN1
Hg19::chr9:131314859..131314877,+p1@SPTAN1
Hg19::chr9:87285539..87285560,+p21@NTRK2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005200structural constituent of cytoskeleton4.99147211879799e-05
GO:0008091spectrin9.70308090475593e-05
GO:0030864cortical actin cytoskeleton0.000136243055220067
GO:0051693actin filament capping0.000136243055220067
GO:0051016barbed-end actin filament capping0.000136243055220067
GO:0030835negative regulation of actin filament depolymerization0.000136243055220067
GO:0030834regulation of actin filament depolymerization0.000136243055220067
GO:0030042actin filament depolymerization0.000136243055220067
GO:0030863cortical cytoskeleton0.000143580142384078
GO:0015629actin cytoskeleton0.000213216949059869
GO:0008064regulation of actin polymerization and/or depolymerization0.000290516615129923
GO:0044448cell cortex part0.000290516615129923
GO:0051261protein depolymerization0.000290516615129923
GO:0030832regulation of actin filament length0.000290516615129923
GO:0032535regulation of cellular component size0.000290516615129923
GO:0032956regulation of actin cytoskeleton organization and biogenesis0.000290516615129923
GO:0051129negative regulation of cellular component organization and biogenesis0.000335265835546014
GO:0051493regulation of cytoskeleton organization and biogenesis0.000343288446968344
GO:0033043regulation of organelle organization and biogenesis0.000343288446968344
GO:0003779actin binding0.000343288446968344
GO:0008154actin polymerization and/or depolymerization0.000374299671112961
GO:0005938cell cortex0.000393507614964763
GO:0008092cytoskeletal protein binding0.000771815799853878
GO:0051128regulation of cellular component organization and biogenesis0.000883182958994439
GO:0051248negative regulation of protein metabolic process0.000917108549270258
GO:0007010cytoskeleton organization and biogenesis0.00100030724883964
GO:0005516calmodulin binding0.00156030768475826
GO:0030036actin cytoskeleton organization and biogenesis0.00459280999558969
GO:0030029actin filament-based process0.00488493878915314
GO:0043121neurotrophin binding0.00488493878915314
GO:0048488synaptic vesicle endocytosis0.00567241467434988
GO:0016043cellular component organization and biogenesis0.00573061625175347
GO:0005856cytoskeleton0.00662604076192401
GO:0006996organelle organization and biogenesis0.00797412921710054
GO:0007016cytoskeletal anchoring0.0091139899944362
GO:0005886plasma membrane0.0091139899944362
GO:0051246regulation of protein metabolic process0.0100232053533945
GO:0030054cell junction0.0100807159878271
GO:0009892negative regulation of metabolic process0.0101401678185353
GO:0007043intercellular junction assembly0.0102515793004705
GO:0045216intercellular junction assembly and maintenance0.0125492597196398
GO:0048489synaptic vesicle transport0.0125492597196398
GO:0007028cytoplasm organization and biogenesis0.0163360075800794
GO:0044459plasma membrane part0.0196488111773652
GO:0005624membrane fraction0.0211664538902833
GO:0005925focal adhesion0.0215907385342878
GO:0005515protein binding0.0215907385342878
GO:0019717synaptosome0.0219321352358375
GO:0005924cell-substrate adherens junction0.0226747890717908
GO:0030055cell-matrix junction0.0233873930407654
GO:0001726ruffle0.0246430376281777
GO:0005912adherens junction0.0302912053126019
GO:0000267cell fraction0.0302912053126019
GO:0019538protein metabolic process0.0302912053126019
GO:0044430cytoskeletal part0.0302912053126019
GO:0043232intracellular non-membrane-bound organelle0.0302912053126019
GO:0043228non-membrane-bound organelle0.0302912053126019
GO:0065008regulation of biological quality0.0313083760599613
GO:0031252leading edge0.0355917882053961
GO:0016323basolateral plasma membrane0.0412782857834084
GO:0048523negative regulation of cellular process0.0417652213505117
GO:0019838growth factor binding0.0418142683574165
GO:0048519negative regulation of biological process0.0435488653287554
GO:0004714transmembrane receptor protein tyrosine kinase activity0.0495374653713563



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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