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|full_id=C1976_Neutrophils_Whole_Eosinophils_CD8_CD19_CD4_blood
|full_id=C1976_Neutrophils_Whole_Eosinophils_CD8_CD19_CD4_blood
|id=C1976
|id=C1976
|ontology_enrichment_celltype=CL:0000738!4.28e-51!140;CL:0000037!1.34e-46!172;CL:0000566!1.34e-46!172;CL:0002032!1.85e-43!165;CL:0000837!1.85e-43!165;CL:0002087!1.90e-42!119;CL:0000988!3.75e-42!182;CL:0002031!3.32e-41!124;CL:0000542!8.67e-26!53;CL:0000051!8.67e-26!53;CL:0000838!2.48e-25!52;CL:0000766!5.80e-21!76;CL:0000763!1.71e-18!112;CL:0000049!1.71e-18!112;CL:0002057!1.87e-18!42;CL:0000557!8.95e-17!71;CL:0000839!2.21e-16!70;CL:0002194!2.42e-15!63;CL:0000576!2.42e-15!63;CL:0000040!2.42e-15!63;CL:0000559!2.42e-15!63;CL:0002009!2.52e-15!65;CL:0000860!4.16e-15!45;CL:0000084!1.61e-12!25;CL:0000827!1.61e-12!25;CL:0000945!2.34e-12!24;CL:0000826!2.34e-12!24;CL:0000791!8.41e-12!18;CL:0000789!8.41e-12!18;CL:0002420!8.41e-12!18;CL:0002419!8.41e-12!18;CL:0000790!8.41e-12!18;CL:0000134!8.07e-09!358;CL:0000236!1.14e-08!14;CL:0000625!3.65e-08!11;CL:0002320!1.01e-07!365
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!6.40e-23!102;UBERON:0003061!6.40e-23!102;UBERON:0002193!7.11e-23!112;UBERON:0007023!2.94e-15!115;UBERON:0002371!1.78e-13!80;UBERON:0002405!1.21e-11!115;UBERON:0001474!2.89e-11!86;UBERON:0004765!1.57e-09!101;UBERON:0001434!1.57e-09!101;UBERON:0000178!1.30e-08!15;UBERON:0000179!1.30e-08!15;UBERON:0000463!1.30e-08!15;UBERON:0003081!2.62e-08!216
}}
}}

Revision as of 14:18, 21 May 2012


Full id: C1976_Neutrophils_Whole_Eosinophils_CD8_CD19_CD4_blood



Phase1 CAGE Peaks

Hg19::chr6:24851973..24851977,-p@chr6:24851973..24851977
-
Hg19::chr6:24923083..24923087,-p@chr6:24923083..24923087
-
Hg19::chr6:24936170..24936199,-p1@FAM65B
Hg19::chr6:31548877..31548898,+p2@AK095821
Hg19::chr8:101963707..101963755,-p8@YWHAZ


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
leukocyte4.28e-51140
hematopoietic stem cell1.34e-46172
angioblastic mesenchymal cell1.34e-46172
hematopoietic oligopotent progenitor cell1.85e-43165
hematopoietic multipotent progenitor cell1.85e-43165
nongranular leukocyte1.90e-42119
hematopoietic cell3.75e-42182
hematopoietic lineage restricted progenitor cell3.32e-41124
lymphocyte8.67e-2653
common lymphoid progenitor8.67e-2653
lymphoid lineage restricted progenitor cell2.48e-2552
myeloid leukocyte5.80e-2176
myeloid cell1.71e-18112
common myeloid progenitor1.71e-18112
CD14-positive, CD16-negative classical monocyte1.87e-1842
granulocyte monocyte progenitor cell8.95e-1771
myeloid lineage restricted progenitor cell2.21e-1670
monopoietic cell2.42e-1563
monocyte2.42e-1563
monoblast2.42e-1563
promonocyte2.42e-1563
macrophage dendritic cell progenitor2.52e-1565
classical monocyte4.16e-1545
T cell1.61e-1225
pro-T cell1.61e-1225
lymphocyte of B lineage2.34e-1224
pro-B cell2.34e-1224
mature alpha-beta T cell8.41e-1218
alpha-beta T cell8.41e-1218
immature T cell8.41e-1218
mature T cell8.41e-1218
immature alpha-beta T cell8.41e-1218
mesenchymal cell8.07e-09358
B cell1.14e-0814
CD8-positive, alpha-beta T cell3.65e-0811
connective tissue cell1.01e-07365
Uber Anatomy
Ontology termp-valuen
hematopoietic system6.40e-23102
blood island6.40e-23102
hemolymphoid system7.11e-23112
adult organism2.94e-15115
bone marrow1.78e-1380
immune system1.21e-11115
bone element2.89e-1186
skeletal element1.57e-09101
skeletal system1.57e-09101
blood1.30e-0815
haemolymphatic fluid1.30e-0815
organism substance1.30e-0815
lateral plate mesoderm2.62e-08216


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.