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(Replaced content with "CNhs11844.10717-109I6.xgmml {{Tf motif cytoscapenw|CNhs=11844|FFid=10717-109I6}}")
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<html>
CNhs11844.10717-109I6.xgmml


<!-- F5 Cytoscape App HTML -->
{{Tf motif cytoscapenw|CNhs=11844|FFid=10717-109I6}}
<div id="f5_cytoscapeweb">
 
<div id="tabs">
<ul>
<li><a href="#style_panel">Layout</a></li>
<li><a href="#filter_panel">Filter</a></li>
<li><a href="#export_panel">Export</a></li>
<li><a href="#properties_panel_nodes">Nodes</a></li>
<li><a href="#properties_panel_edges">Edges</a></li>
</ul>
<div id="style_panel">
<label class="style">Layout:</label>
<select id="cyto_layout" class="ui-button ui-widget ui-state-default ui-corner-all ui-button-text-only">
  <option value="Preset">Preset</option>
  <option value="ForceDirected">Force Directed</option>
  <option value="Circle">Circle</option>
  <option value="Radial">Radial</option>
  <option value="Tree">Tree</option>
</select>
<button id="cyto_recalc">Recalculate</button>
<label class="style">Labels:</label>
<input type="checkbox" id="cyto_node_labels" checked> Nodes</td></tr>
<br /><input type="checkbox" id="cyto_edge_labels"> Edges</td></tr>
</div>
<div id="filter_panel">
<label class="filter">Show edges:</label>
<input type="checkbox" id="cyto_edges_binds_to" checked>TF->MOTIF</input>
<br /><input type="checkbox" id="cyto_edges_promotes" checked>Promoters</input>
<label class="filter">Z-Score filter:</label>
<table class="slider">
<tr><td></td><td><div id="data_bar"></div></td><td></td></tr>
<tr valign="bottom"><td id="cyto_zscore_min" >0.00</td><td ><div id="slider1" class="sliderbar"></div></td><td id="cyto_zscore_max">1</td></tr>
</table>
<label class="filter">Show nodes:</label>
<input type="checkbox" id="cyto_nodes_tf_src" checked>Source TF (Outdegree = 1)</input>
<br /><input type="checkbox" id="cyto_nodes_tf" checked>Target TF (Outdegree = 0)</input>
<br /><input type="checkbox" id="cyto_nodes_motif" checked>MOTIF</input>
<p />
</div>
<div id="properties_panel_nodes" class="properties_panel">
<div>
<button id="btn_show_select_nodes" class="rt_btn">Show only these nodes</button>
<p /><table id="nodes_list" class="wikitable">
</table>
</div>
</div>
<div id="properties_panel_edges" class="properties_panel">
<div>
<button id="btn_show_select_edges" class="rt_btn">Show only these edges</button>
<p /><table id="edges_list" class="wikitable">
</table>
</div>
</div>
<div id="export_panel">
<label class="export">Export Network:</label>
  <button id="btn_exportGraphml">graphml</button>
  <button id="btn_exportXgmml">xgmml</button>
  <button id="btn_exportSIF">sif</button>
  <button id="btn_exportJSON">JSON</button>
<label class="export">Export Image:</label>
  <button id="btn_exportPDF">PDF</button>
  <button id="btn_exportPNG">PNG</button>
  <button id="btn_exportSVG">SVG</button>
</div>
</div>
 
<div id="cytoscapeweb"></div>
<p /><b>LEGEND:</b> <span class="tf">TF <img src="/resource_browser/nwfiles/tf.png" /></span>, <span class="motif">MOTIF <img src="/resource_browser/nwfiles/motif.png" /></span>,
<br /><span class="tf">MOTIF->TF <img src="/resource_browser/nwfiles/motif-tf.png" /></span>, <span class="motif">TF->MOTIF <img src="/resource_browser/nwfiles/tf-motif.png" /></span>
 
</div>
 
<!-- Header Section -->
<!-- JQuery UI -->
<script type="text/javascript" src="/resource_browser/nwfiles/jquery-ui.min.js"></script>
<link href="//ajax.googleapis.com/ajax/libs/jqueryui/1.8.10/themes/base/jquery-ui.css" rel="stylesheet" />
<link href="//ajax.googleapis.com/ajax/libs/jqueryui/1.8.10/themes/redmond/jquery-ui.css" rel="stylesheet" />
 
        <!-- JSON support for IE (needed to use JS API) -->
        <script type="text/javascript" src="/resource_browser/rb_js/cytoscapeweb/js/min/json2.min.js"></script>
       
        <!-- Flash embedding utility (needed to embed Cytoscape Web) -->
        <script type="text/javascript" src="/resource_browser/rb_js/cytoscapeweb/js/min/AC_OETags.min.js"></script>
       
        <!-- Cytoscape Web JS API (needed to reference org.cytoscapeweb.Visualization) -->
        <script type="text/javascript" src="/resource_browser/rb_js/cytoscapeweb/js/min/cytoscapeweb.min.js"></script>
 
<!-- F5 Cytoscape app -->
<link href="/resource_browser/nwfiles/f5_cytoview.css" rel="stylesheet"/>
        <script type="text/javascript" src="/resource_browser/nwfiles/f5_cytoview_4.js"></script>
 
<!-- Data Loading Section -->
<script type="text/javascript">
// Load Data
//var durl = "/resource_browser/nwfiles/</html>{{{CNhs}}}.{{{FFid}}}.xgmml<html>";
                var durl = "/resource_browser/nwfiles/CNhs11844.10717-109I6.xgmml";
 
//$.get(durl, function(data) {
// xml = data;
// //alert('Load was performed.');
//})
 
var request = new XMLHttpRequest();
request.open("GET", durl , false);
request.send(null);
var xml = request.responseText;
 
// initialization cytoscape options
var options = {
swfPath: "/resource_browser/rb_js/cytoscapeweb/swf/CytoscapeWeb",
flashInstallerPath: "/resource_browser/rb_js/cytoscapeweb/swf/playerProductInstall"
};
</script>
 
</html>

Revision as of 13:53, 5 June 2012

CNhs11844.10717-109I6.xgmml

TF
, MOTIF
Promoter
TF-MOTIF Binding
Nodes
Edges
TF-MOTIF Binding
Promoters
Promoter Z-Score filter:

Motif degree filter:
TF indegree filter:
Source TF (Outdegree > 0)
Target TF (Outdegree = 0)


Union: A || B
Intersection: A && B
Difference: A - B
Difference: B - A
Subnetwork: A
Subnetwork: B

About this network view.

Motifs shown are the top motifs in the sample (maximum 30). TFs shown have at least one CAGE promoter with at at least 10 TPM expression (RLE normalized) in the sample. Edges shown have a z-score of at least 1.5 (based on correlation between motif activity and promoter expression).

In the single sample view motifs are shown in orange, TFs are shown in blue. Promoter and z-score are attributes of the Motif to TF edges (blue arrow). TF to Motif edges are shown in orange.

How to interact with the network?

Zoom using the control panel in the lower right.
Click and drag to move nodes.
Double click to search for label in resource browser.
Mouse over nodes and edges to see additional attributes.
Hover over a node to highlight its first neighbors.
Click and drag or shift-click on the canvas to highlight many nodes and edges.
Right click on a node to select its first neighbors.
Right click to show only selected nodes.
When nodes are selected additional information is available in the pull out panel.
Addition filters are available within the pull out panel.

Acknowledgments

Analyst: Erik Arner
Application Developer: Jayson Harshbarger

Research Grant for RIKEN Omics Science Center from MEXT to Yoshihide Hayashizaki
Grant of the Innovative Cell Biology by Innovative Technology (Cell Innovation Program) from the MEXT, Japan to Yoshihide Hayashizaki