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MCL coexpression mm9:200: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0016860;intramolecular oxidoreductase activity;0.0364528008759897;68180,68177!GO:0008903;hydroxypyruvate isomerase activity;0.0364528008759897;68180!GO:0016125;sterol metabolic process;0.0364528008759897;11816,68177!GO:0005159;insulin-like growth factor receptor binding;0.0364528008759897;16000!GO:0047750;cholestenol delta-isomerase activity;0.0364528008759897;68177!GO:0018445;prothoracicotrophic hormone activity;0.0364528008759897;16000!GO:0033143;regulation of steroid hormone receptor signaling pathway;0.0364528008759897;16000!GO:0009653;anatomical structure morphogenesis;0.0364528008759897;11816,16010,16000,18081!GO:0006707;cholesterol catabolic process;0.0364528008759897;11816!GO:0016127;sterol catabolic process;0.0364528008759897;11816!GO:0033344;cholesterol efflux;0.0364528008759897;11816!GO:0008202;steroid metabolic process;0.0364528008759897;11816,68177!GO:0050650;chondroitin sulfate proteoglycan biosynthetic process;0.0364528008759897;16000!GO:0050654;chondroitin sulfate proteoglycan metabolic process;0.0364528008759897;16000!GO:0035239;tube morphogenesis;0.0364528008759897;11816,16000!GO:0016853;isomerase activity;0.0364528008759897;68180,68177!GO:0006706;steroid catabolic process;0.0364528008759897;11816!GO:0065008;regulation of biological quality;0.0364528008759897;11816,16010,16000!GO:0042627;chylomicron;0.0364528008759897;11816!GO:0030104;water homeostasis;0.0364528008759897;16000!GO:0017127;cholesterol transporter activity;0.0364528008759897;11816!GO:0015198;oligopeptide transporter activity;0.0364528008759897;65221!GO:0015248;sterol transporter activity;0.0364528008759897;11816!GO:0015197;peptide transporter activity;0.0364528008759897;65221!GO:0006857;oligopeptide transport;0.0364528008759897;65221!GO:0018987;osmoregulation;0.0364528008759897;16000!GO:0021940;positive regulation of granule cell precursor proliferation;0.0364528008759897;16000!GO:0021936;regulation of granule cell precursor proliferation;0.0364528008759897;16000!GO:0048009;insulin-like growth factor receptor signaling pathway;0.0364528008759897;16000!GO:0035295;tube development;0.0364528008759897;11816,16000!GO:0021534;cell proliferation in hindbrain;0.0364528008759897;16000!GO:0021924;cell proliferation in the external granule layer;0.0364528008759897;16000!GO:0021930;granule cell precursor proliferation;0.0364528008759897;16000!GO:0016861;intramolecular oxidoreductase activity, interconverting aldoses and ketoses;0.0364528008759897;68180!GO:0048878;chemical homeostasis;0.0364528008759897;11816,16000!GO:0031099;regeneration;0.0378566317807004;18081!GO:0042246;tissue regeneration;0.0378566317807004;18081!GO:0006950;response to stress;0.0389874105240323;11816,116891,18081!GO:0030518;steroid hormone receptor signaling pathway;0.0413637874716506;16000!GO:0008034;lipoprotein binding;0.0413637874716506;11816!GO:0042311;vasodilation;0.0424139434841373;11816!GO:0030301;cholesterol transport;0.0424139434841373;11816!GO:0006066;alcohol metabolic process;0.0432302520435786;11816,68177!GO:0015918;sterol transport;0.0432302520435786;11816!GO:0030166;proteoglycan biosynthetic process;0.0432302520435786;16000!GO:0030246;carbohydrate binding;0.0432302520435786;11816,66205!GO:0016863;intramolecular oxidoreductase activity, transposing C=C bonds;0.0432302520435786;68177!GO:0042632;cholesterol homeostasis;0.0432302520435786;11816!GO:0055088;lipid homeostasis;0.0432302520435786;11816!GO:0055092;sterol homeostasis;0.0432302520435786;11816!GO:0030522;intracellular receptor-mediated signaling pathway;0.0448646382369213;16000!GO:0005184;neuropeptide hormone activity;0.0455588305976605;16000!GO:0006029;proteoglycan metabolic process;0.0455588305976605;16000!GO:0005520;insulin-like growth factor binding;0.0493976601030036;16010!}}
{{MCL_coexpression_mm9
|coexpression_dpi_cluster_scores_mean=0.0577601396449535,-0.0617911854930446,-0.0501911964374468,-0.0857313498467563,-0.0914588229465496,-0.093900139165452,-0.0914160483173782,-0.0926236813283793,-0.149558769635981,-0.151352115145198,-0.164330234321684,-0.16254461220186,-0.136911137243573,-0.129391457833858,0.000316878957978749,-0.04210158195144,0.171892442339382,-0.0305747817775088,-0.0208719522261708,0.00436309277926141,0.122268922198373,-0.0997982944725418,-0.118994151258434,0.0497614810308162,0.102211230519983,-0.0577917902679668,-0.0562038834300855,-0.0706184833281575,-0.00444224599576175,-0.0261626965545074,-0.0263627827615751,-0.135592901981357,-0.137874931336803,-0.166296342258835,-0.0808829218602068,-0.0799876370153489,-0.0903384314745974,-0.0834760444100094,-0.0499601169175782,-0.0973247281474649,-0.0576999649640701,-0.0624118249069048,-0.084592506121287,-0.0319833413412078,-0.0392867202762208,-0.0379844266122166,0.454144917800324,0.33335826601472,0.268055511201662,0.427931687469661,0.221292646739217,0.21154077911562,-0.0186609296707444,-0.104381753156211,-0.111898208742664,0.0695699347887097,0.142036427164627,0.319810269700457,-0.069972163536783,-0.0709209991206558,-0.0556284402465282,0.158205416404564,0.174714935530667,1.4953100769316,1.60154396096866,1.47775193844159,1.07954219719503,1.15069562986075,-0.103304907880292,-0.060957149800491,-0.0969916828295288,0.465522615447767,0.495367490739773,-0.104386346535271,-0.103698157790599,-0.108904675738121,0.315458281335413,0.25376897865302,0.262396295905078,-0.0813804356279676,-0.0647885853164605,-0.0792104949233775,0.431536166871323,0.5198252050658,0.460044186994719,0.273587556463035,0.327618447159068,-0.0261642026786641,-0.066579737067926,-0.0170820252839882,0.368675959113,1.25821473271203,1.17323348232251,1.3114261135525,1.39191443176143,1.20395258377389,0.511251232323486,-0.081301466028276,-0.0649713153940709,-0.075420457696284,0.0445769000757438,-0.0715046177036232,-0.142044262676018,-0.158480623528264,-0.0882211917600781,-0.102422290764077,-0.0776258337952624,0.697475071032524,0.0682567528586153,0.141435547171654,0.0301988761151464,0.0756218282817609,0.109873083358308,0.111206997983299,0.0362161026461771,0.0656254667645887,0.302319722477829,0.127297456814489,0.018954476676543,-0.0469015135745128,-0.0410559664440792,0.00226463655464782,0.0106674306942801,0.0486596942353891,0.0805519786255365,0.045711983905679,0.0355501812709355,-0.0093716808397244,-0.00932841297522215,0.112521978050227,0.119067014578137,-0.0498403588788751,0.10283401069289,0.0671104414902978,0.184052165552671,0.0921023863393595,0.0464850457527362,0.0439434012037247,0.143076283761434,0.0893243193521786,-0.018995988992038,-0.014473321639784,-0.0470113634072866,0.0251434143618672,-0.0390790384729196,-0.0282468760077733,-0.00529623739871225,0.10016364167059,-0.109865009226053,-0.0751130473214682,-0.0591441183957195,-0.0160632501242769,-0.038694153518803,-0.046069483685523,-0.0136701186936527,-0.00298028203882804,-0.049251596044702,-0.0410279358313894,-0.0315096841272816,-0.0597497901685814,-0.025189350917974,-0.00999190178982978,-0.0214153858917267,-0.0137646209539294,-0.00494871740295806,-0.0136024072325822,-0.0124078327564509,-0.0396244883392027,-0.0296913619411131,0.00869696270012124,0.00923047821548535,0.0659744798536548,0.0218641720360388,0.0844475582241815,0.0890094471474828,-0.038089758267045,-0.0223072520050586,-0.0338889618640627,-0.0559522734584181,-0.0337778461422442,-0.055658269794327,-0.0410657462338241,-0.0168949616246868,0.015363720668976,0.0704811882282401,0.0689548756980801,0.109821632755345,0.0641557411291031,0.0456426736612247,0.0381378914546252,0.0426106607025461,0.0564662754716751,-0.0433774047913926,-0.0237459085189792,-0.0516718004308452,-0.0238611502806224,-0.00119381604687681,-0.00732287777217106,0.0520271381613092,0.112130077070582,0.0640615336175343,0.0758500258480264,1.03575353963603,0.0154692279921022,0.0470987574489076,0.0956004560916875,0.159759389832096,0.30518173174509,0.491415678190569,0.579712630171623,0.652581655564989,0.850922318392056,1.38588868626593,0.916355767044783,0.987741693103633,0.861376520455719,0.811602762714252,1.00060647577318,0.0672180032072781,-0.0453180768733038,-0.0783026953127058,-0.0545282549246739,-0.0311497191692728,-0.037490004054966,0.0284090083530488,0.0775033604923199,-0.0171656786746028,-0.0102517754786481,-0.00158188136649085,0.0761181418673202,0.066089722059064,0.117878961323862,0.794225864975352,0.474064644660259,0.077423738874325,0.0748136427935716,0.139604533305965,0.111397274358034,-0.151204143252098,0.0170891019169253,0.0516028950229922,0.0424173780992055,0.0814076909203043,0.208413207562879,0.216283723351436,0.192160835622528,0.165814199370187,0.252563941921021,0.164448688078246,0.150590990477096,0.0478407761099605,0.107028003068592,0.00426747746440125,0.100473012677457,-0.00676076537726487,-0.0128273428863179,-0.0122176282571013,-0.00283912781648144,0.0239088360688087,0.0342609155937089,0.0404976533126929,0.05134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|gostat_on_MCL_coexpression=GO:0016860;intramolecular oxidoreductase activity;0.0364528008759897;68180,68177!GO:0008903;hydroxypyruvate isomerase activity;0.0364528008759897;68180!GO:0016125;sterol metabolic process;0.0364528008759897;11816,68177!GO:0005159;insulin-like growth factor receptor binding;0.0364528008759897;16000!GO:0047750;cholestenol delta-isomerase activity;0.0364528008759897;68177!GO:0018445;prothoracicotrophic hormone activity;0.0364528008759897;16000!GO:0033143;regulation of steroid hormone receptor signaling pathway;0.0364528008759897;16000!GO:0009653;anatomical structure morphogenesis;0.0364528008759897;11816,16010,16000,18081!GO:0006707;cholesterol catabolic process;0.0364528008759897;11816!GO:0016127;sterol catabolic process;0.0364528008759897;11816!GO:0033344;cholesterol efflux;0.0364528008759897;11816!GO:0008202;steroid metabolic process;0.0364528008759897;11816,68177!GO:0050650;chondroitin sulfate proteoglycan biosynthetic process;0.0364528008759897;16000!GO:0050654;chondroitin sulfate proteoglycan metabolic process;0.0364528008759897;16000!GO:0035239;tube morphogenesis;0.0364528008759897;11816,16000!GO:0016853;isomerase activity;0.0364528008759897;68180,68177!GO:0006706;steroid catabolic process;0.0364528008759897;11816!GO:0065008;regulation of biological quality;0.0364528008759897;11816,16010,16000!GO:0042627;chylomicron;0.0364528008759897;11816!GO:0030104;water homeostasis;0.0364528008759897;16000!GO:0017127;cholesterol transporter activity;0.0364528008759897;11816!GO:0015198;oligopeptide transporter activity;0.0364528008759897;65221!GO:0015248;sterol transporter activity;0.0364528008759897;11816!GO:0015197;peptide transporter activity;0.0364528008759897;65221!GO:0006857;oligopeptide transport;0.0364528008759897;65221!GO:0018987;osmoregulation;0.0364528008759897;16000!GO:0021940;positive regulation of granule cell precursor proliferation;0.0364528008759897;16000!GO:0021936;regulation of granule cell precursor proliferation;0.0364528008759897;16000!GO:0048009;insulin-like growth factor receptor signaling pathway;0.0364528008759897;16000!GO:0035295;tube development;0.0364528008759897;11816,16000!GO:0021534;cell proliferation in hindbrain;0.0364528008759897;16000!GO:0021924;cell proliferation in the external granule layer;0.0364528008759897;16000!GO:0021930;granule cell precursor proliferation;0.0364528008759897;16000!GO:0016861;intramolecular oxidoreductase activity, interconverting aldoses and ketoses;0.0364528008759897;68180!GO:0048878;chemical homeostasis;0.0364528008759897;11816,16000!GO:0031099;regeneration;0.0378566317807004;18081!GO:0042246;tissue regeneration;0.0378566317807004;18081!GO:0006950;response to stress;0.0389874105240323;11816,116891,18081!GO:0030518;steroid hormone receptor signaling pathway;0.0413637874716506;16000!GO:0008034;lipoprotein binding;0.0413637874716506;11816!GO:0042311;vasodilation;0.0424139434841373;11816!GO:0030301;cholesterol transport;0.0424139434841373;11816!GO:0006066;alcohol metabolic process;0.0432302520435786;11816,68177!GO:0015918;sterol transport;0.0432302520435786;11816!GO:0030166;proteoglycan biosynthetic process;0.0432302520435786;16000!GO:0030246;carbohydrate binding;0.0432302520435786;11816,66205!GO:0016863;intramolecular oxidoreductase activity, transposing C
}}

Revision as of 11:04, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:87322381..87322392,+p20@Igf1
Mm9::chr11:70832735..70832769,-p1@Derl2
Mm9::chr11:98913110..98913132,+p@chr11:98913110..98913132
+
Mm9::chr13:49282854..49282908,+p1@Ninj1
Mm9::chr14:25852233..25852235,-p@chr14:25852233..25852235
-
Mm9::chr14:61979232..61979299,-p1@Ebpl
Mm9::chr19:10917253..10917258,+p4@Slc15a3
Mm9::chr2:60122349..60122358,-p3@Cd302
Mm9::chr4:118032587..118032637,+p1@Hyi
Mm9::chr4:144483030..144483054,+p3@Dhrs3
Mm9::chr4:144483208..144483223,+p4@Dhrs3
Mm9::chr7:135036978..135036995,-p@chr7:135036978..135036995
-
Mm9::chr7:20281617..20281623,+p@chr7:20281617..20281623
+
Mm9::chr7:20281641..20281678,-p@chr7:20281641..20281678
-
Mm9::chr7:20281669..20281686,+p@chr7:20281669..20281686
+
Mm9::chr7:20281713..20281745,+p@chr7:20281713..20281745
+
Mm9::chr7:20281715..20281736,-p@chr7:20281715..20281736
-
Mm9::chr7:20281750..20281788,-p@chr7:20281750..20281788
-
Mm9::chr7:20281778..20281790,+p@chr7:20281778..20281790
+
Mm9::chr7:20281798..20281809,-p@chr7:20281798..20281809
-
Mm9::chr7:20281847..20281854,-p@chr7:20281847..20281854
-
Mm9::chr7:20281878..20281903,+p@chr7:20281878..20281903
+
Mm9::chr7:20281910..20281921,+p@chr7:20281910..20281921
+
Mm9::chr7:20281932..20281988,-p@chr7:20281932..20281988
-
Mm9::chr7:20281997..20282023,-p@chr7:20281997..20282023
-
Mm9::chr7:20282030..20282052,-p@chr7:20282030..20282052
-
Mm9::chr7:20282060..20282097,-p@chr7:20282060..20282097
-
Mm9::chr7:20282155..20282173,-p@chr7:20282155..20282173
-
Mm9::chr7:20282217..20282244,-p@chr7:20282217..20282244
-
Mm9::chr7:20282223..20282246,+p@chr7:20282223..20282246
+
Mm9::chr7:20282263..20282292,-p@chr7:20282263..20282292
-
Mm9::chr7:20282292..20282308,+p@chr7:20282292..20282308
+
Mm9::chr7:20282296..20282318,-p@chr7:20282296..20282318
-
Mm9::chr7:20282325..20282339,+p@chr7:20282325..20282339
+
Mm9::chr7:20282330..20282384,-p@chr7:20282330..20282384
-
Mm9::chr7:20282360..20282433,+p@chr7:20282360..20282433
+
Mm9::chr7:20282392..20282404,-p@chr7:20282392..20282404
-
Mm9::chr7:20282410..20282460,-p@chr7:20282410..20282460
-
Mm9::chr7:20282814..20282847,+p@chr7:20282814..20282847
+
Mm9::chr7:20282853..20282871,-p@chr7:20282853..20282871
-
Mm9::chr7:20282883..20282937,-p@chr7:20282883..20282937
-
Mm9::chr7:20282943..20282956,-p@chr7:20282943..20282956
-
Mm9::chr7:20282961..20282984,-p@chr7:20282961..20282984
-
Mm9::chr7:20282989..20283002,-p@chr7:20282989..20283002
-
Mm9::chr7:20283555..20283610,-p2@Apoe
Mm9::chr7:20284394..20284412,-p1@Apoe
Mm9::chr7:56653449..56653462,+p@chr7:56653449..56653462
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016860intramolecular oxidoreductase activity0.0364528008759897
GO:0008903hydroxypyruvate isomerase activity0.0364528008759897
GO:0016125sterol metabolic process0.0364528008759897
GO:0005159insulin-like growth factor receptor binding0.0364528008759897
GO:0047750cholestenol delta-isomerase activity0.0364528008759897
GO:0018445prothoracicotrophic hormone activity0.0364528008759897
GO:0033143regulation of steroid hormone receptor signaling pathway0.0364528008759897
GO:0009653anatomical structure morphogenesis0.0364528008759897
GO:0006707cholesterol catabolic process0.0364528008759897
GO:0016127sterol catabolic process0.0364528008759897
GO:0033344cholesterol efflux0.0364528008759897
GO:0008202steroid metabolic process0.0364528008759897
GO:0050650chondroitin sulfate proteoglycan biosynthetic process0.0364528008759897
GO:0050654chondroitin sulfate proteoglycan metabolic process0.0364528008759897
GO:0035239tube morphogenesis0.0364528008759897
GO:0016853isomerase activity0.0364528008759897
GO:0006706steroid catabolic process0.0364528008759897
GO:0065008regulation of biological quality0.0364528008759897
GO:0042627chylomicron0.0364528008759897
GO:0030104water homeostasis0.0364528008759897
GO:0017127cholesterol transporter activity0.0364528008759897
GO:0015198oligopeptide transporter activity0.0364528008759897
GO:0015248sterol transporter activity0.0364528008759897
GO:0015197peptide transporter activity0.0364528008759897
GO:0006857oligopeptide transport0.0364528008759897
GO:0018987osmoregulation0.0364528008759897
GO:0021940positive regulation of granule cell precursor proliferation0.0364528008759897
GO:0021936regulation of granule cell precursor proliferation0.0364528008759897
GO:0048009insulin-like growth factor receptor signaling pathway0.0364528008759897
GO:0035295tube development0.0364528008759897
GO:0021534cell proliferation in hindbrain0.0364528008759897
GO:0021924cell proliferation in the external granule layer0.0364528008759897
GO:0021930granule cell precursor proliferation0.0364528008759897
GO:0016861intramolecular oxidoreductase activity, interconverting aldoses and ketoses0.0364528008759897
GO:0048878chemical homeostasis0.0364528008759897
GO:0031099regeneration0.0378566317807004
GO:0042246tissue regeneration0.0378566317807004
GO:0006950response to stress0.0389874105240323
GO:0030518steroid hormone receptor signaling pathway0.0413637874716506
GO:0008034lipoprotein binding0.0413637874716506
GO:0042311vasodilation0.0424139434841373
GO:0030301cholesterol transport0.0424139434841373
GO:0006066alcohol metabolic process0.0432302520435786
GO:0015918sterol transport0.0432302520435786
GO:0030166proteoglycan biosynthetic process0.0432302520435786
GO:0030246carbohydrate binding0.0432302520435786
GO:0016863intramolecular oxidoreductase activity, transposing C



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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