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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0046655;folic acid metabolic process;0.0129926996099939;14275!GO:0006620;posttranslational protein targeting to membrane;0.0129926996099939;14275!GO:0008517;folic acid transporter activity;0.0129926996099939;14275!GO:0042744;hydrogen peroxide catabolic process;0.0129926996099939;14778!GO:0051183;vitamin transporter activity;0.0129926996099939;14275!GO:0051184;cofactor transporter activity;0.0129926996099939;14275!GO:0042743;hydrogen peroxide metabolic process;0.0129926996099939;14778!GO:0004602;glutathione peroxidase activity;0.0129926996099939;14778!GO:0042221;response to chemical stimulus;0.0129926996099939;110877,14778!GO:0042542;response to hydrogen peroxide;0.0129926996099939;14778!GO:0005542;folic acid binding;0.0129926996099939;14275!GO:0006760;folic acid and derivative metabolic process;0.0131002542059473;14275!GO:0042558;pteridine and derivative metabolic process;0.0132689330088039;14275!GO:0015893;drug transport;0.0132689330088039;110877!GO:0015238;drug transporter activity;0.0133362479456937;110877!GO:0000302;response to reactive oxygen species;0.0142872710132106;14778!GO:0045047;protein targeting to ER;0.0159655011936602;14275!GO:0006612;protein targeting to membrane;0.0204800353436179;14275!GO:0006800;oxygen and reactive oxygen species metabolic process;0.0204800353436179;14778!GO:0042493;response to drug;0.0204800353436179;110877!GO:0008430;selenium binding;0.0204800353436179;14778!GO:0004601;peroxidase activity;0.0204800353436179;14778!GO:0016684;oxidoreductase activity, acting on peroxide as acceptor;0.0204800353436179;14778!GO:0006767;water-soluble vitamin metabolic process;0.0231875628053499;14275!GO:0006979;response to oxidative stress;0.0256762365123254;14778!GO:0006836;neurotransmitter transport;0.0263302697303201;110877!GO:0006752;group transfer coenzyme metabolic process;0.0285150748081131;14275!GO:0006766;vitamin metabolic process;0.0315564122737057;14275!GO:0046483;heterocycle metabolic process;0.0324268387677364;14275!GO:0019842;vitamin binding;0.049761938506236;14275!}}
{{MCL_coexpression_mm9
|coexpression_dpi_cluster_scores_mean=-0.0443627545745107,-0.00994553272089218,-0.0142650111703229,-0.0347670242510549,-0.0274855523046066,-0.0157457798897987,-0.010148539372847,-0.0730230804855385,-0.0716526569345937,-0.0704892392728878,-0.0741951111163523,-0.0741951111163523,-0.0726699703523267,-0.0725774454687959,-0.0392204888079678,-0.0308106923429762,-0.0582888057540841,-0.0630213710777952,-0.0679161883655137,-0.0707811375638887,0.907219693527317,-0.0732814966031336,-0.0741951111163523,0.0130606800594569,-0.000406806515516856,-0.0187914708576864,-0.0203447140574684,-0.00518481108568026,-0.029090264022098,-0.0300090073017004,-0.0113916096719603,-0.0441176754418613,-0.0367816290229722,-0.0741951111163523,-0.0643343976573449,-0.0655865191462168,-0.0588396874277809,-0.028627670873603,-0.0237597635407112,-0.0442496107339611,-0.0415511966728652,-0.0395265433822553,-0.0431646193246327,-0.0711028522458373,-0.0714814947606103,-0.0693160832501053,0.295381734527513,0.132701368884709,0.330029402850709,0.369184105432792,0.135287558009503,0.0135349847014524,-0.06876352280871,-0.0741951111163523,-0.0741951111163523,0.562661243122518,0.893076063667282,0.822115005138028,-0.0277576006765435,-0.0315499446826373,-0.0462395305355911,0.0872020763395588,0.107353407250247,0.12887487010962,0.175945095722769,0.185707790401166,0.0546694658325397,0.0767205106075091,-0.0531311457106907,-0.0439340791097867,-0.0564296044856807,0.0371874056648139,0.0280596205731353,-0.0516922904620262,-0.0502620739577574,-0.0614191764260941,-0.00345370827240406,0.0398315944678364,0.041923514644208,-0.0307619882895006,-0.0229993118183113,-0.0277383608845702,0.0820342072504017,0.149517358741923,0.129017946160258,0.0180535625453052,0.0274496011755899,0.00200799014007201,-0.0389982241610768,-0.0254546005073914,-0.0376328994714402,-0.0198473759301164,-0.0615166766053428,-0.0560292609520892,-0.0443558191310981,-0.0425678120294955,0.601723916673948,0.0519819095160984,0.0341297759703456,0.0541843461495188,-0.0580237380679331,-0.0662271938611423,-0.0741951111163523,-0.0741951111163523,-0.0431334064322819,-0.0347121734354458,-0.0345714513994439,0.715944300631233,0.113171781494227,0.145656753726366,0.0074505790337336,0.000885560287595798,0.0383861211449129,0.0265420684874507,0.0626507578558529,0.152969496394295,1.09890615658682,0.735692182779516,0.14951388816145,0.0830781429306947,0.138572318244071,0.140573187917292,0.0173652804971735,-0.0206639922372743,-0.0327929625683605,0.0512167768327102,-0.0617130567557124,-0.0623855729810356,-0.0564886950313735,0.0133674289697145,-0.0119608241342473,-0.0443845898183905,-0.0428077892609376,-0.038527686982686,0.00876132154770365,-0.0171156997695925,0.113391851889346,0.315332005985249,0.640218239486431,0.0718111520890368,-0.0166105552859501,-0.0148959407123084,-0.00763647650279303,-0.024284489702137,-0.0220505453739986,-0.00947641126725692,-0.0155635572284257,0.0211051289425021,-0.0202454268818801,0.000205023266937993,-0.031006310220681,-0.0104110509018751,0.00727329909441897,0.0519448683084743,-0.0318324683298707,0.0124113482848567,-0.0559571680884203,-0.0358598619235259,-0.0407218329446125,0.325548145718418,0.269650117012337,0.273745895225308,0.263897825760421,0.194133076714761,0.238408687063311,0.216879276394062,0.217423985479596,0.224277130069145,0.190197349293365,0.160916857974906,0.169004988728212,0.173811217160605,0.201212524329137,0.255050824400716,-0.0375077733500031,-0.0215645984273546,0.0203019125692297,0.0660180082510677,0.0165983005947611,0.041318963497479,0.0673692461966171,0.201904706370733,0.374369879479895,0.622273988092038,0.0872639645098741,0.824589586297943,0.782862597697263,0.846165050001555,0.778247620312475,0.089119016055071,0.0697809237390869,0.0841376820347441,0.0217277495760599,0.0243227017599221,0.104381255824863,0.221669313190792,0.317503934023362,0.51904319385136,0.797398381822558,1.12761626357789,1.19873084392994,1.37058903517094,-0.0142535313824301,0.0158270872905517,-0.0164326202679048,-0.00884971816996573,0.00214832265298111,0.0148179395513519,0.00451921112474096,0.0168043165964941,0.0658849543619174,0.00919773824310376,0.0334032153112421,0.0172720381697521,-0.0122016551276649,-0.0197764995093201,-0.0116487377543959,-0.00690498469883522,0.399022507593451,0.0755178294886974,0.0320685235137447,0.0378989718385197,0.0246612686261416,0.0866508283655704,0.200129918512895,0.354854349988428,0.0431936229984481,0.0594602732401798,0.0734772343666015,0.354678559052308,0.371561888516948,0.463508725195465,0.0842607965398867,0.0238365317657704,0.137823085703655,0.248893751640952,0.0144728011538612,0.00238688298080862,-0.0727300287293367,0.181491457850205,-0.0320635164138931,-0.017955208725777,-0.049730581181465,-0.0397363603362874,-0.0293615599461788,-0.0471282031984344,-0.0275915324211976,-0.011279751265632,-0.0170590568533364,-0.0349114952746395,0.299161669687552,0.0327307283069327,0.0347593295916467,0.218917378726188,0.0467677286585951,0.0194370829677984,0.0141972728524884,0.00773439834696813,0.04155870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|gostat_on_MCL_coexpression=GO:0046655;folic acid metabolic process;0.0129926996099939;14275!GO:0006620;posttranslational protein targeting to membrane;0.0129926996099939;14275!GO:0008517;folic acid transporter activity;0.0129926996099939;14275!GO:0042744;hydrogen peroxide catabolic process;0.0129926996099939;14778!GO:0051183;vitamin transporter activity;0.0129926996099939;14275!GO:0051184;cofactor transporter activity;0.0129926996099939;14275!GO:0042743;hydrogen peroxide metabolic process;0.0129926996099939;14778!GO:0004602;glutathione peroxidase activity;0.0129926996099939;14778!GO:0042221;response to chemical stimulus;0.0129926996099939;110877,14778!GO:0042542;response to hydrogen peroxide;0.0129926996099939;14778!GO:0005542;folic acid binding;0.0129926996099939;14275!GO:0006760;folic acid and derivative metabolic process;0.0131002542059473;14275!GO:0042558;pteridine and derivative metabolic process;0.0132689330088039;14275!GO:0015893;drug transport;0.0132689330088039;110877!GO:0015238;drug transporter activity;0.0133362479456937;110877!GO:0000302;response to reactive oxygen species;0.0142872710132106;14778!GO:0045047;protein targeting to ER;0.0159655011936602;14275!GO:0006612;protein targeting to membrane;0.0204800353436179;14275!GO:0006800;oxygen and reactive oxygen species metabolic process;0.0204800353436179;14778!GO:0042493;response to drug;0.0204800353436179;110877!GO:0008430;selenium binding;0.0204800353436179;14778!GO:0004601;peroxidase activity;0.0204800353436179;14778!GO:0016684;oxidoreductase activity, acting on peroxide as acceptor;0.0204800353436179;14778!GO:0006767;water-soluble vitamin metabolic process;0.0231875628053499;14275!GO:0006979;response to oxidative stress;0.0256762365123254;14778!GO:0006836;neurotransmitter transport;0.0263302697303201;110877!GO:0006752;group transfer coenzyme metabolic process;0.0285150748081131;14275!GO:0006766;vitamin metabolic process;0.0315564122737057;14275!GO:0046483;heterocycle metabolic process;0.0324268387677364;14275!GO:0019842;vitamin binding;0.049761938506236;14275!
}}

Revision as of 11:04, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:54716245..54716271,+p1@ENSMUST00000082430
Mm9::chr11:54716419..54716434,+p1@Gpx3
Mm9::chr11:54717503..54717508,+p@chr11:54717503..54717508
+
Mm9::chr11:54720620..54720632,+p@chr11:54720620..54720632
+
Mm9::chr11:54720634..54720662,+p@chr11:54720634..54720662
+
Mm9::chr11:54720669..54720679,+p@chr11:54720669..54720679
+
Mm9::chr11:54720687..54720702,+p@chr11:54720687..54720702
+
Mm9::chr11:54720706..54720748,+p@chr11:54720706..54720748
+
Mm9::chr11:54720735..54720787,-p@chr11:54720735..54720787
-
Mm9::chr11:54722037..54722059,+p@chr11:54722037..54722059
+
Mm9::chr11:54722061..54722106,+p@chr11:54722061..54722106
+
Mm9::chr11:54722066..54722076,-p@chr11:54722066..54722076
-
Mm9::chr11:54722111..54722118,+p@chr11:54722111..54722118
+
Mm9::chr11:54722125..54722139,+p@chr11:54722125..54722139
+
Mm9::chr11:54722126..54722137,-p@chr11:54722126..54722137
-
Mm9::chr11:54722142..54722153,-p@chr11:54722142..54722153
-
Mm9::chr11:54722554..54722569,+p@chr11:54722554..54722569
+
Mm9::chr11:54722563..54722573,-p@chr11:54722563..54722573
-
Mm9::chr11:54722604..54722615,+p@chr11:54722604..54722615
+
Mm9::chr11:54722965..54722978,+p@chr11:54722965..54722978
+
Mm9::chr11:54723041..54723052,+p@chr11:54723041..54723052
+
Mm9::chr11:54723124..54723135,+p@chr11:54723124..54723135
+
Mm9::chr11:54723146..54723186,+p@chr11:54723146..54723186
+
Mm9::chr11:54723159..54723189,-p@chr11:54723159..54723189
-
Mm9::chr11:54723193..54723270,-p@chr11:54723193..54723270
-
Mm9::chr11:54723200..54723262,+p@chr11:54723200..54723262
+
Mm9::chr11:54723287..54723290,-p@chr11:54723287..54723290
-
Mm9::chr11:54723294..54723305,-p@chr11:54723294..54723305
-
Mm9::chr11:54723295..54723306,+p@chr11:54723295..54723306
+
Mm9::chr11:54723332..54723333,+p@chr11:54723332..54723333
+
Mm9::chr11:54723346..54723358,+p@chr11:54723346..54723358
+
Mm9::chr11:54723377..54723386,-p@chr11:54723377..54723386
-
Mm9::chr11:54723394..54723405,+p@chr11:54723394..54723405
+
Mm9::chr11:54723408..54723426,+p@chr11:54723408..54723426
+
Mm9::chr11:54723429..54723448,-p@chr11:54723429..54723448
-
Mm9::chr11:54723437..54723448,+p@chr11:54723437..54723448
+
Mm9::chr11:54723480..54723489,-p@chr11:54723480..54723489
-
Mm9::chr11:54723495..54723510,-p@chr11:54723495..54723510
-
Mm9::chr11:54723520..54723533,+p@chr11:54723520..54723533
+
Mm9::chr11:54723531..54723579,-p@chr11:54723531..54723579
-
Mm9::chr11:54723607..54723615,-p@chr11:54723607..54723615
-
Mm9::chr11:54723871..54723882,-p@chr11:54723871..54723882
-
Mm9::chr5:104224204..104224209,-p@chr5:104224204..104224209
-
Mm9::chr7:109017821..109017858,-p3@Folr1
Mm9::chr8:71613099..71613114,-p1@Slc18a1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0046655folic acid metabolic process0.0129926996099939
GO:0006620posttranslational protein targeting to membrane0.0129926996099939
GO:0008517folic acid transporter activity0.0129926996099939
GO:0042744hydrogen peroxide catabolic process0.0129926996099939
GO:0051183vitamin transporter activity0.0129926996099939
GO:0051184cofactor transporter activity0.0129926996099939
GO:0042743hydrogen peroxide metabolic process0.0129926996099939
GO:0004602glutathione peroxidase activity0.0129926996099939
GO:0042221response to chemical stimulus0.0129926996099939
GO:0042542response to hydrogen peroxide0.0129926996099939
GO:0005542folic acid binding0.0129926996099939
GO:0006760folic acid and derivative metabolic process0.0131002542059473
GO:0042558pteridine and derivative metabolic process0.0132689330088039
GO:0015893drug transport0.0132689330088039
GO:0015238drug transporter activity0.0133362479456937
GO:0000302response to reactive oxygen species0.0142872710132106
GO:0045047protein targeting to ER0.0159655011936602
GO:0006612protein targeting to membrane0.0204800353436179
GO:0006800oxygen and reactive oxygen species metabolic process0.0204800353436179
GO:0042493response to drug0.0204800353436179
GO:0008430selenium binding0.0204800353436179
GO:0004601peroxidase activity0.0204800353436179
GO:0016684oxidoreductase activity, acting on peroxide as acceptor0.0204800353436179
GO:0006767water-soluble vitamin metabolic process0.0231875628053499
GO:0006979response to oxidative stress0.0256762365123254
GO:0006836neurotransmitter transport0.0263302697303201
GO:0006752group transfer coenzyme metabolic process0.0285150748081131
GO:0006766vitamin metabolic process0.0315564122737057
GO:0046483heterocycle metabolic process0.0324268387677364
GO:0019842vitamin binding0.049761938506236



Relative expression of the co-expression cluster over median <br>Analyst:


"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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