MCL coexpression mm9:700

Phase1 CAGE Peaks

	Short description
Mm9::chr11:113427054..113427106,-	p1@Slc39a11
Mm9::chr11:5420973..5420992,+	p1@Xbp1
Mm9::chr11:84683690..84683732,-	p4@Ggnbp2
Mm9::chr12:70285164..70285205,+	p1@Mgat2
Mm9::chr15:88906488..88906535,+	p1@Trabd
Mm9::chr17:74738503..74738558,+	p@chr17:74738503..74738558 +
Mm9::chr5:31262609..31262693,-	p1@Preb
Mm9::chr5:31262699..31262712,-	p2@Preb
Mm9::chr6:108778627..108778715,+	p1@Edem1
Mm9::chr8:72826660..72826703,+	p1@Cope

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005783	endoplasmic reticulum	0.0226217276537667
GO:0046462	monoacylglycerol metabolic process	0.0380066257364183
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	0.0380066257364183
GO:0003846	2-acylglycerol O-acyltransferase activity	0.0380066257364183
GO:0019432	triacylglycerol biosynthetic process	0.0380066257364183
GO:0006651	diacylglycerol biosynthetic process	0.0380066257364183
GO:0030433	ER-associated protein catabolic process	0.0380066257364183
GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	0.0380066257364183
GO:0006515	misfolded or incompletely synthesized protein catabolic process	0.0380066257364183
GO:0043231	intracellular membrane-bound organelle	0.0380066257364183
GO:0043227	membrane-bound organelle	0.0380066257364183
GO:0015924	mannosyl-oligosaccharide mannosidase activity	0.0380066257364183
GO:0046460	neutral lipid biosynthetic process	0.0380066257364183
GO:0046463	acylglycerol biosynthetic process	0.0380066257364183
GO:0046504	glycerol ether biosynthetic process	0.0380066257364183
GO:0045017	glycerolipid biosynthetic process	0.0380066257364183
GO:0046339	diacylglycerol metabolic process	0.0380066257364183
GO:0050892	intestinal absorption	0.0380066257364183
GO:0030126	COPI vesicle coat	0.0380066257364183
GO:0030663	COPI coated vesicle membrane	0.0380066257364183
GO:0044444	cytoplasmic part	0.042213393607381
GO:0030137	COPI-coated vesicle	0.042213393607381
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	0.0429068815323417
GO:0022600	digestive system process	0.0429068815323417
GO:0016411	acylglycerol O-acyltransferase activity	0.0429068815323417
GO:0015923	mannosidase activity	0.0429068815323417
GO:0031410	cytoplasmic vesicle	0.0429068815323417
GO:0043229	intracellular organelle	0.0429068815323417
GO:0012505	endomembrane system	0.0429068815323417
GO:0043226	organelle	0.0429068815323417
GO:0031982	vesicle	0.0431141534842245
GO:0006641	triacylglycerol metabolic process	0.0481607130753447
GO:0006071	glycerol metabolic process	0.0481607130753447
GO:0019751	polyol metabolic process	0.0481607130753447
GO:0030176	integral to endoplasmic reticulum membrane	0.0481607130753447
GO:0006829	zinc ion transport	0.0497453160918431
GO:0005737	cytoplasm	0.0497453160918431
GO:0031227	intrinsic to endoplasmic reticulum membrane	0.0497453160918431
GO:0030120	vesicle coat	0.0497453160918431
GO:0006639	acylglycerol metabolic process	0.0497453160918431
GO:0046486	glycerolipid metabolic process	0.0497453160918431
GO:0006638	neutral lipid metabolic process	0.0497453160918431
GO:0030662	coated vesicle membrane	0.0497453160918431
GO:0006662	glycerol ether metabolic process	0.0497453160918431

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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