MCL coexpression mm9:1067

Phase1 CAGE Peaks

	Short description
Mm9::chr11:3166345..3166356,-	p2@Drg1
Mm9::chr11:57981969..57982046,-	p1@Gemin5
Mm9::chr11:82594646..82594726,+	p1@Lig3
Mm9::chr19:42007766..42007809,-	p1@Exosc1
Mm9::chr2:30141926..30141962,+	p1@Nup188
Mm9::chr3:137806393..137806441,+	p1@Rg9mtd2
Mm9::chr7:52650585..52650599,-	p2@Snrnp70

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003723	RNA binding	0.00283615803609444
GO:0006396	RNA processing	0.00986854879041573
GO:0044428	nuclear part	0.00986854879041573
GO:0005634	nucleus	0.0170882624622196
GO:0003676	nucleic acid binding	0.0229985721377707
GO:0005681	spliceosome	0.0229985721377707
GO:0003909	DNA ligase activity	0.0229985721377707
GO:0003910	DNA ligase (ATP) activity	0.0229985721377707
GO:0016886	ligase activity, forming phosphoric ester bonds	0.0255497690801792
GO:0032991	macromolecular complex	0.0417743685416616
GO:0000178	exosome (RNase complex)	0.0417743685416616
GO:0008175	tRNA methyltransferase activity	0.042115565933889
GO:0045576	mast cell activation	0.0424031109006837

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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