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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0006368;RNA elongation from RNA polymerase II promoter;0.00849082427874535;192657!GO:0008159;positive transcription elongation factor activity;0.00849082427874535;192657!GO:0003711;transcription elongation regulator activity;0.00849082427874535;192657!GO:0006354;RNA elongation;0.00849082427874535;192657!GO:0031018;endocrine pancreas development;0.00950920211147191;18576!GO:0050796;regulation of insulin secretion;0.01245116183932;18576!GO:0031016;pancreas development;0.0126121740103004;18576!GO:0046883;regulation of hormone secretion;0.0131238398324806;18576!GO:0030073;insulin secretion;0.0131238398324806;18576!GO:0004114;3',5'-cyclic-nucleotide phosphodiesterase activity;0.0131238398324806;18576!GO:0004112;cyclic-nucleotide phosphodiesterase activity;0.0131238398324806;18576!GO:0042593;glucose homeostasis;0.0131238398324806;18576!GO:0030072;peptide hormone secretion;0.0131238398324806;18576!GO:0033500;carbohydrate homeostasis;0.0131238398324806;18576!GO:0002790;peptide secretion;0.0131238398324806;18576!GO:0003746;translation elongation factor activity;0.0131514028315503;192657!GO:0015833;peptide transport;0.0151698640205953;18576!GO:0046879;hormone secretion;0.0154569084645442;18576!GO:0035270;endocrine system development;0.0171401863879458;18576!GO:0051046;regulation of secretion;0.0176381730482426;18576!GO:0008081;phosphoric diester hydrolase activity;0.0209903367375198;18576!GO:0003001;generation of a signal involved in cell-cell signaling;0.0268015332072241;18576!GO:0008135;translation factor activity, nucleic acid binding;0.0341544463540627;192657!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0006368;RNA elongation from RNA polymerase II promoter;0.00849082427874535;192657!GO:0008159;positive transcription elongation factor activity;0.00849082427874535;192657!GO:0003711;transcription elongation regulator activity;0.00849082427874535;192657!GO:0006354;RNA elongation;0.00849082427874535;192657!GO:0031018;endocrine pancreas development;0.00950920211147191;18576!GO:0050796;regulation of insulin secretion;0.01245116183932;18576!GO:0031016;pancreas development;0.0126121740103004;18576!GO:0046883;regulation of hormone secretion;0.0131238398324806;18576!GO:0030073;insulin secretion;0.0131238398324806;18576!GO:0004114;3',5'-cyclic-nucleotide phosphodiesterase activity;0.0131238398324806;18576!GO:0004112;cyclic-nucleotide phosphodiesterase activity;0.0131238398324806;18576!GO:0042593;glucose homeostasis;0.0131238398324806;18576!GO:0030072;peptide hormone secretion;0.0131238398324806;18576!GO:0033500;carbohydrate homeostasis;0.0131238398324806;18576!GO:0002790;peptide secretion;0.0131238398324806;18576!GO:0003746;translation elongation factor activity;0.0131514028315503;192657!GO:0015833;peptide transport;0.0151698640205953;18576!GO:0046879;hormone secretion;0.0154569084645442;18576!GO:0035270;endocrine system development;0.0171401863879458;18576!GO:0051046;regulation of secretion;0.0176381730482426;18576!GO:0008081;phosphoric diester hydrolase activity;0.0209903367375198;18576!GO:0003001;generation of a signal involved in cell-cell signaling;0.0268015332072241;18576!GO:0008135;translation factor activity, nucleic acid binding;0.0341544463540627;192657!
}}

Revision as of 11:31, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr13:75901337..75901359,+p@chr13:75901337..75901359
+
Mm9::chr5:35385070..35385084,+p@chr5:35385070..35385084
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Mm9::chr5:35389132..35389142,+p@chr5:35389132..35389142
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Mm9::chr7:121638077..121638090,+p@chr7:121638077..121638090
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006368RNA elongation from RNA polymerase II promoter0.00849082427874535
GO:0008159positive transcription elongation factor activity0.00849082427874535
GO:0003711transcription elongation regulator activity0.00849082427874535
GO:0006354RNA elongation0.00849082427874535
GO:0031018endocrine pancreas development0.00950920211147191
GO:0050796regulation of insulin secretion0.01245116183932
GO:0031016pancreas development0.0126121740103004
GO:0046883regulation of hormone secretion0.0131238398324806
GO:0030073insulin secretion0.0131238398324806
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.0131238398324806
GO:0004112cyclic-nucleotide phosphodiesterase activity0.0131238398324806
GO:0042593glucose homeostasis0.0131238398324806
GO:0030072peptide hormone secretion0.0131238398324806
GO:0033500carbohydrate homeostasis0.0131238398324806
GO:0002790peptide secretion0.0131238398324806
GO:0003746translation elongation factor activity0.0131514028315503
GO:0015833peptide transport0.0151698640205953
GO:0046879hormone secretion0.0154569084645442
GO:0035270endocrine system development0.0171401863879458
GO:0051046regulation of secretion0.0176381730482426
GO:0008081phosphoric diester hydrolase activity0.0209903367375198
GO:0003001generation of a signal involved in cell-cell signaling0.0268015332072241
GO:0008135translation factor activity, nucleic acid binding0.0341544463540627



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}