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MCL coexpression mm9:326: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0045740;positive regulation of DNA replication;0.0402497060598641;13874!GO:0004360;glutamine-fructose-6-phosphate transaminase (isomerizing) activity;0.0402497060598641;14584!GO:0045741;positive regulation of epidermal growth factor receptor activity;0.0402497060598641;13874!GO:0005588;collagen type V;0.0402497060598641;12832!GO:0045840;positive regulation of mitosis;0.0402497060598641;13874!GO:0048661;positive regulation of smooth muscle cell proliferation;0.0402497060598641;13874!GO:0048660;regulation of smooth muscle cell proliferation;0.0402497060598641;13874!GO:0051054;positive regulation of DNA metabolic process;0.0402497060598641;13874!GO:0007176;regulation of epidermal growth factor receptor activity;0.0402497060598641;13874!GO:0045742;positive regulation of epidermal growth factor receptor signaling pathway;0.0425893257526012;13874!GO:0005583;fibrillar collagen;0.0425893257526012;12832!GO:0030036;actin cytoskeleton organization and biogenesis;0.0425893257526012;11641,80837!GO:0048659;smooth muscle cell proliferation;0.0425893257526012;13874!GO:0030029;actin filament-based process;0.0425893257526012;11641,80837!GO:0045410;positive regulation of interleukin-6 biosynthetic process;0.0425893257526012;13874!GO:0042058;regulation of epidermal growth factor receptor signaling pathway;0.0425893257526012;13874!GO:0004720;protein-lysine 6-oxidase activity;0.0425893257526012;94352!GO:0008284;positive regulation of cell proliferation;0.0433274084684527;13874,11535!GO:0005154;epidermal growth factor receptor binding;0.0444475374244391;13874!GO:0051018;protein kinase A binding;0.0482467528778367;11641!
|gostat_on_MCL_coexpression=GO:0045740;positive regulation of DNA replication;0.0402497060598641;13874!GO:0004360;glutamine-fructose-6-phosphate transaminase (isomerizing) activity;0.0402497060598641;14584!GO:0045741;positive regulation of epidermal growth factor receptor activity;0.0402497060598641;13874!GO:0005588;collagen type V;0.0402497060598641;12832!GO:0045840;positive regulation of mitosis;0.0402497060598641;13874!GO:0048661;positive regulation of smooth muscle cell proliferation;0.0402497060598641;13874!GO:0048660;regulation of smooth muscle cell proliferation;0.0402497060598641;13874!GO:0051054;positive regulation of DNA metabolic process;0.0402497060598641;13874!GO:0007176;regulation of epidermal growth factor receptor activity;0.0402497060598641;13874!GO:0045742;positive regulation of epidermal growth factor receptor signaling pathway;0.0425893257526012;13874!GO:0005583;fibrillar collagen;0.0425893257526012;12832!GO:0030036;actin cytoskeleton organization and biogenesis;0.0425893257526012;11641,80837!GO:0048659;smooth muscle cell proliferation;0.0425893257526012;13874!GO:0030029;actin filament-based process;0.0425893257526012;11641,80837!GO:0045410;positive regulation of interleukin-6 biosynthetic process;0.0425893257526012;13874!GO:0042058;regulation of epidermal growth factor receptor signaling pathway;0.0425893257526012;13874!GO:0004720;protein-lysine 6-oxidase activity;0.0425893257526012;94352!GO:0008284;positive regulation of cell proliferation;0.0433274084684527;13874,11535!GO:0005154;epidermal growth factor receptor binding;0.0444475374244391;13874!GO:0051018;protein kinase A binding;0.0482467528778367;11641!
}}
}}

Revision as of 12:40, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:49607659..49607686,+p1@Gfpt2
Mm9::chr12:76409326..76409345,+p4@Rhoj
Mm9::chr14:70008967..70008981,+p1@Loxl2
Mm9::chr1:45499562..45499597,-p@chr1:45499562..45499597
-
Mm9::chr1:45559410..45559413,-p@chr1:45559410..45559413
-
Mm9::chr1:45559901..45559916,-p1@Col5a2
Mm9::chr2:27806885..27806899,+p@chr2:27806885..27806899
+
Mm9::chr4:57858149..57858160,+p5@Akap2
Mm9::chr5:91503323..91503334,+p2@Ereg
Mm9::chr6:91162781..91162792,+p2@Fbln2
Mm9::chr6:91162793..91162838,+p1@Fbln2
Mm9::chr6:91162853..91162864,+p3@Fbln2
Mm9::chr6:91183204..91183213,+p@chr6:91183204..91183213
+
Mm9::chr6:91183472..91183486,+p@chr6:91183472..91183486
+
Mm9::chr6:91183490..91183501,+p@chr6:91183490..91183501
+
Mm9::chr6:91183746..91183762,+p@chr6:91183746..91183762
+
Mm9::chr6:91183788..91183800,+p@chr6:91183788..91183800
+
Mm9::chr6:91183906..91183958,-p@chr6:91183906..91183958
-
Mm9::chr6:91184210..91184231,+p@chr6:91184210..91184231
+
Mm9::chr6:91184284..91184295,+p@chr6:91184284..91184295
+
Mm9::chr6:91222095..91222107,+p@chr6:91222095..91222107
+
Mm9::chr7:105639067..105639106,+p@chr7:105639067..105639106
+
Mm9::chr7:117771164..117771180,+p1@Adm
Mm9::chr7:117772048..117772059,+p@chr7:117772048..117772059
+
Mm9::chr7:26573654..26573729,-p1@Axl


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045740positive regulation of DNA replication0.0402497060598641
GO:0004360glutamine-fructose-6-phosphate transaminase (isomerizing) activity0.0402497060598641
GO:0045741positive regulation of epidermal growth factor receptor activity0.0402497060598641
GO:0005588collagen type V0.0402497060598641
GO:0045840positive regulation of mitosis0.0402497060598641
GO:0048661positive regulation of smooth muscle cell proliferation0.0402497060598641
GO:0048660regulation of smooth muscle cell proliferation0.0402497060598641
GO:0051054positive regulation of DNA metabolic process0.0402497060598641
GO:0007176regulation of epidermal growth factor receptor activity0.0402497060598641
GO:0045742positive regulation of epidermal growth factor receptor signaling pathway0.0425893257526012
GO:0005583fibrillar collagen0.0425893257526012
GO:0030036actin cytoskeleton organization and biogenesis0.0425893257526012
GO:0048659smooth muscle cell proliferation0.0425893257526012
GO:0030029actin filament-based process0.0425893257526012
GO:0045410positive regulation of interleukin-6 biosynthetic process0.0425893257526012
GO:0042058regulation of epidermal growth factor receptor signaling pathway0.0425893257526012
GO:0004720protein-lysine 6-oxidase activity0.0425893257526012
GO:0008284positive regulation of cell proliferation0.0433274084684527
GO:0005154epidermal growth factor receptor binding0.0444475374244391
GO:0051018protein kinase A binding0.0482467528778367



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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